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AC impedance of Ag/AgCl reference electrodes for use in disposable biosensors 一次性生物传感器用Ag/AgCl参比电极的交流阻抗
Dm Zhou, E. McAdams, A. Lackermeier, J.G. Jones
The AC impedance characteristics of chloridized silver-ink electrodes have been investigated. The interface impedance decreases for light deposits and increases upon further coating. There exists, therefore, an optimal chloride deposit which ensures a low interface impedance. This deposit depends on the silver ink used and on the frequency range of interest.<>
研究了氯化银墨电极的交流阻抗特性。界面阻抗在轻沉积时减小,在进一步涂层时增大。因此,存在一种保证低界面阻抗的最佳氯化物沉积。这取决于所使用的银墨水和频率范围的兴趣。
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引用次数: 7
Change of the relationship between superimposed M wave and preceding background activity during muscular fatigue 肌肉疲劳时叠加M波与前期背景活动关系的变化
T. Kiryu, M. Okada, Y. Saitoh
A superimposed M wave is the M wave during a sustained contraction. We estimated a relationship between the instantaneous frequencies (IFs) at specific times of the superimposed M wave and the mean power frequency (MPF) of the preceding background activity during muscular fatigue. The results showed that the relationship was classified into two (complex and simple) types. In the complex type, each behavior of the MPF-IF relationship showed a different manner. Three explicitly separated and the same inclination pattern appeared in the simple type. The decrease in the IFs was higher for the simple type than for the complex type. These types were possibly produced by the individual differences in the contribution of the fast twitch muscle fibers near the surface electrodes to the conduction velocity.<>
叠加的M波是持续收缩时的M波。我们估计了特定时间叠加M波的瞬时频率(if)与肌肉疲劳期间前一背景活动的平均工频(MPF)之间的关系。结果表明,该关系可分为复杂和简单两种类型。在复合型中,强积金-中频关系的各行为表现出不同的方式。在简单型中出现了三个明显分离且相同的倾斜模式。简单型的IFs下降幅度大于复杂型。这些类型可能是由表面电极附近的快肌纤维对传导速度的贡献的个体差异产生的
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引用次数: 3
Control processes in fast movements end before the peak velocity: evidence based on experimental analysis and modelling 快速运动中的控制过程在峰值速度之前结束:基于实验分析和建模的证据
A. G. Feldman, S. Adamovich, N. St-Onge, M. Levin
Both experimental effects of perturbations and computer simulation indicate that shifts in the equilibrium position underlying fast discrete movements of the elbow are completed before the peak velocity of movement and thus before the end of the phasic EMG activity. The authors' results imply that EMG patterns and the resulting kinematics are not preprogrammed but represent long-lasting dynamic responses of the system to this short-duration control pattern combined with the effects of load and peripheral feedback.<>
微扰的实验效果和计算机模拟都表明,肘关节快速离散运动的平衡位置的变化在运动的峰值速度之前完成,因此在相肌电活动结束之前完成。作者的结果表明,肌电图模式和由此产生的运动学不是预先编程的,而是系统对这种短时间控制模式的长期动态响应,结合负载和外围反馈的影响
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引用次数: 1
Computer modeling of the effects of aortic valve stenosis and arterial system afterload on left ventricular hypertrophy 主动脉瓣狭窄及动脉系统后负荷对左室肥厚影响的计算机模拟
Ying Zhu, M. Nanna, J. Li
The degree of left ventricular (LV) hypertrophy is generally thought to reflect the severity of aortic stenosis. However the influence of arterial system characteristics is poorly understood. The authors developed a computer model to investigate the effects of aortic stenosis in combination with various systemic arterial parameters in the development of LV hypertrophy. Data show that an increased peripheral resistance and/or valve resistance, results in an increase in LV wall thickness and mass, while peak systolic wall stress remains constant. Changing arterial compliance to above normal level would not induce changes in wall thickness, while results below normal would cause an increase in wall thickness. When the heart is double loaded, the hypertrophic process is aggregated and shows a greater increase in wall thickness.<>
左室肥厚的程度通常被认为反映主动脉狭窄的严重程度。然而,动脉系统特征的影响尚不清楚。作者建立了一个计算机模型来研究主动脉瓣狭窄与各种全身动脉参数在左室肥厚发展中的作用。数据显示,外周阻力和/或瓣膜阻力增加,导致左室壁厚度和质量增加,而收缩壁应力峰值保持不变。动脉顺应性高于正常值不会引起壁厚变化,低于正常值则会引起壁厚增加。当心脏受到双重负荷时,肥厚过程聚集,壁厚增加更大
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引用次数: 19
Miniature microcontroller-based heart rate telemeter processes single precordial lead 基于微型微控制器的心率遥测仪处理单个心前导联
J.M. Darnieder, D. Jeutter
A miniature single-channel heart rate monitoring device has been developed specifically for use in critical care situations, such as intensive care units. The externally-worn device is placed directly on the chest above the heart, allowing acquisition of the electrocardiogram without the use of leads. The 8-bit microcontroller-based transmitter digitizes the preconditioned ECG and identifies the signal in real-time using a robust QRS detection algorithm. Data is output from the microcontroller only when an abnormal heart rate or low battery voltage is detected. When it is necessary to output data from the device, the digital data is transmitted by frequency modulation to a nearby nurses' station. At the monitoring station, the transmitted data is demodulated by the receiver and processed by another microcontroller which then activates the appropriate alarms.<>
一种微型单通道心率监测装置已经开发出来,专门用于重症监护情况,如重症监护病房。外部佩戴设备直接放置在心脏上方的胸部,无需使用导线即可获取心电图。基于8位微控制器的发射器数字化预处理心电,并使用鲁棒QRS检测算法实时识别信号。只有当检测到心率异常或电池电压过低时,单片机才会输出数据。当需要从设备输出数据时,数字数据通过调频传输到附近的护士站。在监测站,传输的数据由接收器解调,并由另一个微控制器处理,然后激活相应的警报
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引用次数: 3
Simulated action potentials and extracellular potentials in a bundle of muscle fibers 肌肉纤维束的模拟动作电位和细胞外电位
K. Henneberg
In this investigation, computer simulations are used to study the propagating action potential in skeletal muscle. The model considers the influence of the transverse tubular system and the electrical interaction between an active fiber and a single layer of surrounding passive fibers in a fiber bundle.<>
本研究采用计算机模拟的方法研究了骨骼肌的传导动作电位。该模型考虑了横向管状系统的影响以及光纤束中有源光纤与周围单层无源光纤之间的电相互作用。
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引用次数: 0
Use of the fast Hartley transform for efficient 3D convolution in calculation of radiation dose 利用快速哈特利变换进行有效的三维卷积计算辐射剂量
A. Erdi, M. Loew, E. Yorke, Y. Erdi, B. Wessels
In radionuclide therapy, absorbed dose is calculated by convolution of a three-dimensional activity matrix with a three-dimensional dose point kernel. A technique employing the fast Hartley Transform (FHT) has been developed to perform this calculation. An important part of that development was the indexing scheme for 3D data. The results of this new FHT convolution technique were compared to direct convolution. A cube was convolved with itself by these two techniques. The results differed by less than 2 percent. In an effort to show the practical applicability of 3D convolution, a three-dimensional activity matrix from a I-131-labeled 16.88 monoclonal antibody patient was convolved with beta and photon dose point kernels using direct convolution. Isodose contours were then generated from the calculated absorbed dose matrix and overlaid on a CT image of the patient.<>
在放射性核素治疗中,吸收剂量是通过三维活度矩阵与三维剂量点核的卷积来计算的。一种采用快速哈特利变换(FHT)的技术已被开发来执行这种计算。这一发展的一个重要部分是3D数据的索引方案。并与直接卷积的结果进行了比较。一个立方体通过这两种技术与自身进行卷积。结果相差不到2%。为了展示三维卷积的实际适用性,使用直接卷积将来自i -131标记的16.88单克隆抗体患者的三维活性矩阵与β和光子剂量点核进行卷积。然后从计算的吸收剂量矩阵生成等剂量轮廓,并覆盖在患者的CT图像上。
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引用次数: 9
Health care modelling and the lessons from liver transplantation 卫生保健模式和肝移植的经验教训
E. Carson, D. Cramp, H. Leicester
A paradigm is presented for decision support in high dependency patient care. The control loop structure emphasises integrated feedback of data and information, while computerised decision support supplements planning in the clinical context. Liver transplantation highlights the relevance of the paradigm and omissions in the health care system.
提出了一个范例,为决策支持在高依赖病人护理。控制回路结构强调数据和信息的综合反馈,而计算机化决策支持补充了临床环境中的计划。肝移植突出了范例的相关性和卫生保健系统的遗漏。
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引用次数: 0
Wrist flexion/extension control in C5 and C4 quadriplegic subjects using functional neuromuscular stimulation 应用功能性神经肌肉刺激控制C5和C4四肢瘫痪患者的腕屈伸
M. Lemay, P. Crago, M. Keith, P. Peckham
The authors investigated the feasibility of using functional neuromuscular stimulation (FNS) to control wrist angle in C5 tetraplegics. They measured the moments available from the wrist muscles, the moments produced at the wrist by the finger muscles during grasp, and the passive properties of the wrist joint. Furthermore, the authors evaluated three wrist position controllers. They found that the passive and finger muscle moments are significant compared with the moment produced by single wrist muscles and will affect the maximal range of wrist angle obtainable and the stability of the wrist during grasp. Feedback regulation would provide increase wrist stability in the presence of disturbances, with possibly less wrist muscle activation.<>
探讨了应用功能性神经肌肉刺激(FNS)控制C5四肢瘫痪患者手腕角度的可行性。他们测量了手腕肌肉提供的力矩,手指肌肉在抓握时在手腕产生的力矩,以及手腕关节的被动特性。此外,作者评估了三种手腕位置控制器。他们发现,与单个手腕肌肉产生的力矩相比,被动和手指肌肉的力矩是显著的,并且会影响手腕可获得的最大角度范围和手腕在抓握过程中的稳定性。反馈调节将在有干扰的情况下增加手腕的稳定性,可能减少手腕肌肉的激活
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引用次数: 1
Compression of ECG using a code excited linear prediction (CELP) 基于编码激励线性预测(CELP)的心电压缩
L. Wang, J. Belina, A. Vasinonta, M. Berner, S. Ramprashad
A lossy ECG signal compression method using CELP is introduced here. Linear predictive coding (LPC) has been widely used as a compression technique in the field of speech coding. Similar to speech signals, ECG signals can be thought of as being produced by spectrally shaping excitation pulses. The encoder presented uses an analysis by synthesis structure. The short term spectral characteristics of the ECG signal are approximated by an IIR filter using LPC coefficients. Optimal excitations are selected from two codebooks, an adaptive codebook which takes advantage of long term correlation between pulses, and a fixed codebook which models short term changes in the characteristics of individual pulses. Using the MIT/BIH arrhythmia database with a rudimentary fixed codebook the authors were able to achieve a compression ratio of approximately 13:1 with a typical normalized MSE's ranging from 0.017 to 0.033 using a frame size of 200 samples.
本文介绍了一种基于CELP的有损心电信号压缩方法。线性预测编码(LPC)作为一种压缩技术在语音编码领域得到了广泛的应用。与语音信号类似,心电信号可以被认为是由频谱整形激励脉冲产生的。所提出的编码器采用综合结构分析。心电信号的短期频谱特性是由使用LPC系数的IIR滤波器近似。从两个码本中选择最优激励,一个是利用脉冲间长期相关性的自适应码本,另一个是模拟单个脉冲特性短期变化的固定码本。使用MIT/BIH心律失常数据库和一个基本的固定码本,作者能够实现大约13:1的压缩比,典型的归一化MSE范围为0.017到0.033,使用200个样本的帧大小。
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引用次数: 6
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Proceedings of 16th Annual International Conference of the IEEE Engineering in Medicine and Biology Society
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