Pub Date : 2023-07-13DOI: 10.52888/0514-2515-2023-357-2-86-93
U. M. Pirov, A. A. Razzokov
Aim. To enhance the outcomes of surgical treatment of unstable uncomplicated vertebral fractures.Materials and Methods. This research involves an analysis of surgical treatment data from 237 patients aged 18 to 74 years, all with unstable uncomplicated vertebral fractures. These patients underwent surgery using the technique of posterior transpedicular fusion. The primary group, constituting 51.9% of cases, utilized enhanced approaches, while the control group (48.1% of cases) employed standard methods. The treatment outcomes were evaluated using a newly developed scale, while the Oswestry scale was used to gauge the quality of life.Results and Discussion. The primary components of the refined surgical treatment tactics used in the main group were low-traumatic manipulations, which aimed to minimize tissue trauma and avert intraoperative complications. Utilizing the proposed objective scoring method, a statistically significant improvement in long-term outcomes was established in the primary group compared to the control group, with scores of 95.5±0.4 points and 88.7±0.7 points respectively (P<0.05). According to the Oswestry scale, the sum of points in the main group was 2.5±0.05, compared to 5.1±0.06 in the control group. The Oswestry index in the analyzed groups was 7.1±1.6 and 22.4±1.2 respectively.Conclusion. The findings demonstrate a statistically significant increase in the proportion of favorable outcomes, and the absence of unsatisfactory results, in the primary group as compared to the control group. Furthermore, an improvement in the quality of life for patients in the primary group was observed.
{"title":"Surgical treatment of unstable uncomplicated vertebral fractures","authors":"U. M. Pirov, A. A. Razzokov","doi":"10.52888/0514-2515-2023-357-2-86-93","DOIUrl":"https://doi.org/10.52888/0514-2515-2023-357-2-86-93","url":null,"abstract":"Aim. To enhance the outcomes of surgical treatment of unstable uncomplicated vertebral fractures.Materials and Methods. This research involves an analysis of surgical treatment data from 237 patients aged 18 to 74 years, all with unstable uncomplicated vertebral fractures. These patients underwent surgery using the technique of posterior transpedicular fusion. The primary group, constituting 51.9% of cases, utilized enhanced approaches, while the control group (48.1% of cases) employed standard methods. The treatment outcomes were evaluated using a newly developed scale, while the Oswestry scale was used to gauge the quality of life.Results and Discussion. The primary components of the refined surgical treatment tactics used in the main group were low-traumatic manipulations, which aimed to minimize tissue trauma and avert intraoperative complications. Utilizing the proposed objective scoring method, a statistically significant improvement in long-term outcomes was established in the primary group compared to the control group, with scores of 95.5±0.4 points and 88.7±0.7 points respectively (P<0.05). According to the Oswestry scale, the sum of points in the main group was 2.5±0.05, compared to 5.1±0.06 in the control group. The Oswestry index in the analyzed groups was 7.1±1.6 and 22.4±1.2 respectively.Conclusion. The findings demonstrate a statistically significant increase in the proportion of favorable outcomes, and the absence of unsatisfactory results, in the primary group as compared to the control group. Furthermore, an improvement in the quality of life for patients in the primary group was observed.","PeriodicalId":345517,"journal":{"name":"Health care of Tajikistan","volume":"20 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126396007","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-07-13DOI: 10.52888/0514-2515-2023-357-2-113-119
M. Shoev
The study incorporated treatment for 75 patients experiencing chronic purulent maxillitis exacerbation, employing the use of phytopreparations. After comprehensive examination, all patients were prescribed antibiotic therapy and decongestants, and subsequently underwent a maxillary sinus puncture. Patients in the first primary group underwent thrice-daily sinus cavity washes with a medicinal sage infusion. In contrast, the second primary group was treated with a hypericum perforatum infusion. For the comparison group, a 0.02% furacilin solution was utilized as an antiseptic for the puncture and wash of the maxillary sinus. The findings substantiate the advisability of prescribing the examined drugs to patients enduring an exacerbation of chronic purulent maxillitis.
{"title":"Experience in the use of phytotherapy in patients with exacerbation of chronic sinusitis","authors":"M. Shoev","doi":"10.52888/0514-2515-2023-357-2-113-119","DOIUrl":"https://doi.org/10.52888/0514-2515-2023-357-2-113-119","url":null,"abstract":"The study incorporated treatment for 75 patients experiencing chronic purulent maxillitis exacerbation, employing the use of phytopreparations. After comprehensive examination, all patients were prescribed antibiotic therapy and decongestants, and subsequently underwent a maxillary sinus puncture. Patients in the first primary group underwent thrice-daily sinus cavity washes with a medicinal sage infusion. In contrast, the second primary group was treated with a hypericum perforatum infusion. For the comparison group, a 0.02% furacilin solution was utilized as an antiseptic for the puncture and wash of the maxillary sinus. The findings substantiate the advisability of prescribing the examined drugs to patients enduring an exacerbation of chronic purulent maxillitis.","PeriodicalId":345517,"journal":{"name":"Health care of Tajikistan","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129854373","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-07-13DOI: 10.52888/0514-2515-2023-357-2-100-105
S. Satorov, S. N. Mavlonazarova, S. Yusufi
This work presents the results of studies on the extract obtained from the root of Ferula kuhistanica Korov, in relation to 2 strains of the influenza virus: A/Vlad/2/09(H1N1) and A/Almaty/8/98(H3N2). It has been shown that the F. kuhistanica Korov extract exhibits selective antiviral activity and primarily acts on the influenza virus strain A/Vlad/2/09(H1N1), not showing an inhibitory effect against another antigenic variant of this virus – the strain A/ Almaty/8/98(H3N2). The tested extract was characterized by high IC50, EC50, and IS50 indicators. Its chemotherapeutic effect (XTI) is 23 times higher than that of the commercial anti-influenza drug - Tamiflu. The data obtained open up prospects for the possible use of extracts obtained from the root of various species of the genus Ferula, growing in our country, in the development of anti-influenza drugs.
{"title":"Antiviral effect of the Ferula Kuhistanica Korovin plant, growing in the high-mountain conditions of the Republic of Tajikistan","authors":"S. Satorov, S. N. Mavlonazarova, S. Yusufi","doi":"10.52888/0514-2515-2023-357-2-100-105","DOIUrl":"https://doi.org/10.52888/0514-2515-2023-357-2-100-105","url":null,"abstract":"This work presents the results of studies on the extract obtained from the root of Ferula kuhistanica Korov, in relation to 2 strains of the influenza virus: A/Vlad/2/09(H1N1) and A/Almaty/8/98(H3N2). It has been shown that the F. kuhistanica Korov extract exhibits selective antiviral activity and primarily acts on the influenza virus strain A/Vlad/2/09(H1N1), not showing an inhibitory effect against another antigenic variant of this virus – the strain A/ Almaty/8/98(H3N2). The tested extract was characterized by high IC50, EC50, and IS50 indicators. Its chemotherapeutic effect (XTI) is 23 times higher than that of the commercial anti-influenza drug - Tamiflu. The data obtained open up prospects for the possible use of extracts obtained from the root of various species of the genus Ferula, growing in our country, in the development of anti-influenza drugs.","PeriodicalId":345517,"journal":{"name":"Health care of Tajikistan","volume":"9 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128315146","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-07-13DOI: 10.52888/0514-2515-2023-357-2-105-112
Z. Tilloeva, A. Mirzoev
Aim. To evaluate the shifts in demographic, clinical, and epidemiological characteristics of patients with multidrugresistant tuberculosis (MDR TB) amidst the COVID-19 pandemic.Materials and Methods. A cross-sectional study was conducted on patients with MDR TB registered in Dushanbe, before (2017-2019) and during the COVID-19 pandemic (2020-2021).Results. The average age of patients prior to the COVID-19 pandemic was 36.5±16.9 years (1.7-79.4), whereas during the COVID-19 period, it was 34.4±17 years (2.9-80.2). The pandemic era witnessed a statistically significant rise in the proportion of workers among MDR TB patients compared to the unemployed (OR = 1.4; 95% CI 1.02-1.91; p = 0.05). Furthermore, an increase was observed in the proportion of patients with lung destruction in both newly diagnosed (OR 3.4; 95% CI 1.99–5.87; p<0.001) and previously treated patients (OR 4.2; 95% CI 1.38–12.99; p =0.002). There was also an increase in extrapulmonary tuberculosis registration (OR=1.7; 95% CI 1.34-2.22; p<0.001), indicating an unfavorable epidemiological situation in terms of MDR-TB. However, there were no statistically significant changes in the registration of concomitant diseases.Conclusion. We recommend the improvement of TB infection prevention and control measures at all levels, as well as the enhancement of early detection of TB and MDR TB patients by primary health care workers.
的目标。评估在COVID-19大流行期间耐多药结核病(MDR TB)患者的人口统计学、临床和流行病学特征的变化。材料与方法。对2019冠状病毒病大流行之前(2017-2019)和期间(2020-2021)在杜尚别登记的耐多药结核病患者进行了横断面研究。新冠肺炎流行前患者平均年龄为36.5±16.9岁(1.7 ~ 79.4岁)，新冠肺炎流行期间患者平均年龄为34.4±17岁(2.9 ~ 80.2岁)。在大流行时期，与失业者相比，耐多药结核病患者中工人的比例在统计上显著上升(OR = 1.4;95% ci 1.02-1.91;P = 0.05)。此外，在新诊断的两组患者中，观察到肺破坏患者的比例增加(OR 3.4;95% ci 1.99-5.87;p<0.001)和以前治疗过的患者(OR 4.2;95% ci 1.38-12.99;p = 0.002)。肺外结核登记也有所增加(OR=1.7;95% ci 1.34-2.22;p<0.001)，表明在耐多药结核病方面存在不利的流行病学形势。然而，伴随疾病的登记没有统计学上的显著变化。我们建议改进各级结核病感染预防和控制措施，并加强初级卫生保健工作者对结核病和耐多药结核病患者的早期发现。
{"title":"Multi-drug-resistant tuberculosis in COVID-19 pandemic period, Dushanbe","authors":"Z. Tilloeva, A. Mirzoev","doi":"10.52888/0514-2515-2023-357-2-105-112","DOIUrl":"https://doi.org/10.52888/0514-2515-2023-357-2-105-112","url":null,"abstract":"Aim. To evaluate the shifts in demographic, clinical, and epidemiological characteristics of patients with multidrugresistant tuberculosis (MDR TB) amidst the COVID-19 pandemic.Materials and Methods. A cross-sectional study was conducted on patients with MDR TB registered in Dushanbe, before (2017-2019) and during the COVID-19 pandemic (2020-2021).Results. The average age of patients prior to the COVID-19 pandemic was 36.5±16.9 years (1.7-79.4), whereas during the COVID-19 period, it was 34.4±17 years (2.9-80.2). The pandemic era witnessed a statistically significant rise in the proportion of workers among MDR TB patients compared to the unemployed (OR = 1.4; 95% CI 1.02-1.91; p = 0.05). Furthermore, an increase was observed in the proportion of patients with lung destruction in both newly diagnosed (OR 3.4; 95% CI 1.99–5.87; p<0.001) and previously treated patients (OR 4.2; 95% CI 1.38–12.99; p =0.002). There was also an increase in extrapulmonary tuberculosis registration (OR=1.7; 95% CI 1.34-2.22; p<0.001), indicating an unfavorable epidemiological situation in terms of MDR-TB. However, there were no statistically significant changes in the registration of concomitant diseases.Conclusion. We recommend the improvement of TB infection prevention and control measures at all levels, as well as the enhancement of early detection of TB and MDR TB patients by primary health care workers.","PeriodicalId":345517,"journal":{"name":"Health care of Tajikistan","volume":"40 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133993805","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-07-12DOI: 10.52888/0514-2515-2023-357-2-37-44
M. K. Gulov, J. S. Salimov, J. K. Mukhabbatov, S. Ali-Zade, K. N. Nosiri
Aim. To detect intestinal ischemia promptly in patients with acute adhesive small bowel obstruction.Methods. A total of 124 patients with acute adhesive small bowel obstruction were studied. Logistic regression analysis was performed to determine the most significant prognostic factors for intestinal ischemia. The derived regression coefficient indicators were utilized in a scoring system.Results. Six independent prognostic factors of intestinal ischemia were identified: age, duration of pain, body temperature, white blood cell count, reduced intestinal wall contrast, and localized mesenteric edema visible on a CT scan. Regression coefficient scores were attributed to each variable associated with intestinal ischemia. The predicted occurrence of bowel ischemia was computed as a sum of scores ranging from 0 to 24. A threshold of 6 points was used to define the low-probability group (risk of bowel ischemia was 1.13%). A score between 7 and 15 determined the intermediate-probability group (the risk of intestinal ischemia was 44%). A score of ≥16 defined the high-probability group (all patients in this group had intestinal ischemia).Conclusions. The risk prediction assessment of bowel ischemia was performed with high accuracy (above 90%). This evaluation is reliable and reproducible, hence it may aid the surgeon to differentiate patients with intestinal ischemia for surgical intervention. Since ischemic disorders may be reversible, this could prevent the development of intestinal necrosis.
{"title":"Predicting of intestinal ischemia in patients with adhesive small bowel obstruction","authors":"M. K. Gulov, J. S. Salimov, J. K. Mukhabbatov, S. Ali-Zade, K. N. Nosiri","doi":"10.52888/0514-2515-2023-357-2-37-44","DOIUrl":"https://doi.org/10.52888/0514-2515-2023-357-2-37-44","url":null,"abstract":"Aim. To detect intestinal ischemia promptly in patients with acute adhesive small bowel obstruction.Methods. A total of 124 patients with acute adhesive small bowel obstruction were studied. Logistic regression analysis was performed to determine the most significant prognostic factors for intestinal ischemia. The derived regression coefficient indicators were utilized in a scoring system.Results. Six independent prognostic factors of intestinal ischemia were identified: age, duration of pain, body temperature, white blood cell count, reduced intestinal wall contrast, and localized mesenteric edema visible on a CT scan. Regression coefficient scores were attributed to each variable associated with intestinal ischemia. The predicted occurrence of bowel ischemia was computed as a sum of scores ranging from 0 to 24. A threshold of 6 points was used to define the low-probability group (risk of bowel ischemia was 1.13%). A score between 7 and 15 determined the intermediate-probability group (the risk of intestinal ischemia was 44%). A score of ≥16 defined the high-probability group (all patients in this group had intestinal ischemia).Conclusions. The risk prediction assessment of bowel ischemia was performed with high accuracy (above 90%). This evaluation is reliable and reproducible, hence it may aid the surgeon to differentiate patients with intestinal ischemia for surgical intervention. Since ischemic disorders may be reversible, this could prevent the development of intestinal necrosis.","PeriodicalId":345517,"journal":{"name":"Health care of Tajikistan","volume":"71 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126514040","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-07-12DOI: 10.52888/0514-2515-2023-357-2-15-22
N. G. Asilova
Aim. To assess cognitive and speech functions in patients with cerebral palsy and their relationship with the location of the pathological focus and gender.Material and methods. We examined 125 children aged 7-9 years with a final diagnosis of cerebral palsy, hemiplegic form (G80.2). The patients were divided into 2 groups depending on the location of the hemispheric focus. Group I consisted of 72 patients with left-sided hemiparesis (LHP), 33 girls and 39 boys. Group II consisted of 53 patients with right-sided hemiparesis (RHP), 23 girls and 30 boys. The control group included 30 practically healthy children (16 boys and 14 girls) without neurological pathology with an average age of 7.3±1.5 years.Results and discussion. Children with LHP more often had disturbances in the tempo and prosodic characteristics of speech (43.7%). The rate of speech was disturbed in 33.8% of children, narrative speech - in 14.1%. These disorders are called "right hemispheric cortical dysarthria". Counting disorders were noted in 4.2% of children.In the group with RHP, violations of expressive speech were stated: "monologic" - in 88.7%, "dialogical" - in 86.8%, "automated" - in 17.0% of patients, not fluent speech - in 66.0%, slow - in 64.2%.Conclusion. The results of the study indicate a high degree of correlation of speech disorders and impaired cognitive functions with the severity of hemiparesis and structural changes on MRI of the brain. These results significantly differ from the corresponding indicators depending on the side of hemiparesis and sex. Determination of cognitive evoked potentials makes it possible to obtain additional information about the cognitive status of patients with cerebral palsy, depending on the lateralization of the lesion.
{"title":"Cognitive and speech disorders in patients with hemiparetic form of childhood cerebral palsy","authors":"N. G. Asilova","doi":"10.52888/0514-2515-2023-357-2-15-22","DOIUrl":"https://doi.org/10.52888/0514-2515-2023-357-2-15-22","url":null,"abstract":"Aim. To assess cognitive and speech functions in patients with cerebral palsy and their relationship with the location of the pathological focus and gender.Material and methods. We examined 125 children aged 7-9 years with a final diagnosis of cerebral palsy, hemiplegic form (G80.2). The patients were divided into 2 groups depending on the location of the hemispheric focus. Group I consisted of 72 patients with left-sided hemiparesis (LHP), 33 girls and 39 boys. Group II consisted of 53 patients with right-sided hemiparesis (RHP), 23 girls and 30 boys. The control group included 30 practically healthy children (16 boys and 14 girls) without neurological pathology with an average age of 7.3±1.5 years.Results and discussion. Children with LHP more often had disturbances in the tempo and prosodic characteristics of speech (43.7%). The rate of speech was disturbed in 33.8% of children, narrative speech - in 14.1%. These disorders are called \"right hemispheric cortical dysarthria\". Counting disorders were noted in 4.2% of children.In the group with RHP, violations of expressive speech were stated: \"monologic\" - in 88.7%, \"dialogical\" - in 86.8%, \"automated\" - in 17.0% of patients, not fluent speech - in 66.0%, slow - in 64.2%.Conclusion. The results of the study indicate a high degree of correlation of speech disorders and impaired cognitive functions with the severity of hemiparesis and structural changes on MRI of the brain. These results significantly differ from the corresponding indicators depending on the side of hemiparesis and sex. Determination of cognitive evoked potentials makes it possible to obtain additional information about the cognitive status of patients with cerebral palsy, depending on the lateralization of the lesion.","PeriodicalId":345517,"journal":{"name":"Health care of Tajikistan","volume":"437 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122883417","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-07-12DOI: 10.52888/0514-2515-2023-357-2-29-37
M. Akhmadzoda, A. T. Khomidov, F. Rashidov, H. Boboev, B. D. Safarov
Aim. To evaluate comparatively the outcomes of diagnostic procedures and surgical treatment for combined echinococcosis of the liver and lungs, utilizing state-of-the-art diagnostic methods and innovative echinococcectomy technologies.Materials and Methods. A comparative assessment was undertaken on the surgical treatment outcomes for 188 patients (100 in the control group; 88 in the main group) afflicted with combined liver and lung echinococcosis (CLLE). The main group of patients were subjected to contemporary diagnostic techniques and cryotechnology during the echinococcectomy process. A total of 188 patients with CLLE were hospitalized and underwent 234 surgical procedures. The surgical treatment for combined echinococcosis of the liver and lungs was conducted, adhering strictly to the principles of aparasitism and antiparasitism.Results. Specific postoperative complications, such as localized hydrothorax and pneumothorax, bronchial fistula, biloma, perihepatic fluid accumulations, and wound suppurations, were identified in 24% of the surgically treated patients in the control group, leading to repeat surgical interventions in 6% of these cases. In the main group, postoperative complications were observed in 9.7% of patients, with only a single case (1.38%) necessitating relaparotomy. No fatalities were reported in either of the study groups.Conclusion. The application of ultra-low temperature liquid nitrogen in surgery for combined echinococcosis of the liver and lungs, as an integral part of aparasitic and antiparasitic measures, proves to be a highly effective therapeutic technology. The uncomplicated progression of liver and lung echinococcosis facilitates a one-stage surgical operation.
{"title":"Surgical treatment of combined echinococcosis of the liver and lungs","authors":"M. Akhmadzoda, A. T. Khomidov, F. Rashidov, H. Boboev, B. D. Safarov","doi":"10.52888/0514-2515-2023-357-2-29-37","DOIUrl":"https://doi.org/10.52888/0514-2515-2023-357-2-29-37","url":null,"abstract":"Aim. To evaluate comparatively the outcomes of diagnostic procedures and surgical treatment for combined echinococcosis of the liver and lungs, utilizing state-of-the-art diagnostic methods and innovative echinococcectomy technologies.Materials and Methods. A comparative assessment was undertaken on the surgical treatment outcomes for 188 patients (100 in the control group; 88 in the main group) afflicted with combined liver and lung echinococcosis (CLLE). The main group of patients were subjected to contemporary diagnostic techniques and cryotechnology during the echinococcectomy process. A total of 188 patients with CLLE were hospitalized and underwent 234 surgical procedures. The surgical treatment for combined echinococcosis of the liver and lungs was conducted, adhering strictly to the principles of aparasitism and antiparasitism.Results. Specific postoperative complications, such as localized hydrothorax and pneumothorax, bronchial fistula, biloma, perihepatic fluid accumulations, and wound suppurations, were identified in 24% of the surgically treated patients in the control group, leading to repeat surgical interventions in 6% of these cases. In the main group, postoperative complications were observed in 9.7% of patients, with only a single case (1.38%) necessitating relaparotomy. No fatalities were reported in either of the study groups.Conclusion. The application of ultra-low temperature liquid nitrogen in surgery for combined echinococcosis of the liver and lungs, as an integral part of aparasitic and antiparasitic measures, proves to be a highly effective therapeutic technology. The uncomplicated progression of liver and lung echinococcosis facilitates a one-stage surgical operation.","PeriodicalId":345517,"journal":{"name":"Health care of Tajikistan","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131169233","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-07-12DOI: 10.52888/0514-2515-2023-357-2-77-86
О. Nematzoda, D. D. Sultanov, A. Gaibov, B. G. Muminzoda, O. F. Soliev, H. Yunusov
Aim. To evaluate effectiveness of the scleroobliteration in the treatment of small-diameter varicose veins.Materials and Methods. The analysis incorporated the results of sclerotherapy in 135 patients, comprising those with telangiectasias and reticular varicose veins (n=95) and those with varicose dilation of aberrant subcutaneous veins (n=40) with intact trunks of major and/or minor subcutaneous veins of the lower extremities. The sample included 111 women (82.2%) and 24 men (17.8%), with an average age of 35.2±6.5 years.For the obliteration of expanded subcutaneous veins, two sclerotherapy techniques were employed: liquid (n=65) and foam-form (n=70), prepared as per the L. Tessari method. Sclerosants used were a 0.5–3% sodium tetradecyl sulfate solution (“Fibro vein”) (ATC code: C05BB04) (n=69) or a 1-3% polidocanol solution (“Ethoxisclerol”) (ATC code: C05BB02) (n=66).A detailed analysis was carried out of all complications that developed during and at various times post-sclerotherapy, and the effectiveness of the treatment, which depended on the diameter of the expanded veins and the thoroughness of the procedure.Results. The technical success of the procedure was registered at 100%. The overall frequency of complications post-sclerotherapy was 20.7%, including 27.7% with the liquid form and 14.3% with the foam form of sclerosants (p<0.001). Intradermal and subcutaneous hemorrhages were observed in 10 (7.4%) patients, allergic reactions in 8 (5.9%), localized skin necrosis in 3 (2.2%), folliculitis in 3 (2.2%), and localized purulent complications in 2 (1.5%). Micro-air embolism of the pulmonary artery branches due to exceeding the established norm of air volume during foam sclerotherapy was recorded in 2 (2.9%) cases.Following one session, a positive sclerotherapy effect was noted in 45.9% of patients. The necessity for additional sclerotherapy courses was indicated for over half the patients, with the effectiveness rising to 97.8% after 3 or more courses.Conclusion. Sclerotherapy, being an effective minimally invasive method, is significantly impactful in treating reticular varices and telangiectasias. Greater efficiency and a lower rate of complications have been observed with the use of foam form sclerosant. Proper selection of sclerosant volume and concentration is essential for the prevention and reduction of sclerotherapy complications.
{"title":"The place of sclerotherapy in the treatment of varicose vein disease","authors":"О. Nematzoda, D. D. Sultanov, A. Gaibov, B. G. Muminzoda, O. F. Soliev, H. Yunusov","doi":"10.52888/0514-2515-2023-357-2-77-86","DOIUrl":"https://doi.org/10.52888/0514-2515-2023-357-2-77-86","url":null,"abstract":"Aim. To evaluate effectiveness of the scleroobliteration in the treatment of small-diameter varicose veins.Materials and Methods. The analysis incorporated the results of sclerotherapy in 135 patients, comprising those with telangiectasias and reticular varicose veins (n=95) and those with varicose dilation of aberrant subcutaneous veins (n=40) with intact trunks of major and/or minor subcutaneous veins of the lower extremities. The sample included 111 women (82.2%) and 24 men (17.8%), with an average age of 35.2±6.5 years.For the obliteration of expanded subcutaneous veins, two sclerotherapy techniques were employed: liquid (n=65) and foam-form (n=70), prepared as per the L. Tessari method. Sclerosants used were a 0.5–3% sodium tetradecyl sulfate solution (“Fibro vein”) (ATC code: C05BB04) (n=69) or a 1-3% polidocanol solution (“Ethoxisclerol”) (ATC code: C05BB02) (n=66).A detailed analysis was carried out of all complications that developed during and at various times post-sclerotherapy, and the effectiveness of the treatment, which depended on the diameter of the expanded veins and the thoroughness of the procedure.Results. The technical success of the procedure was registered at 100%. The overall frequency of complications post-sclerotherapy was 20.7%, including 27.7% with the liquid form and 14.3% with the foam form of sclerosants (p<0.001). Intradermal and subcutaneous hemorrhages were observed in 10 (7.4%) patients, allergic reactions in 8 (5.9%), localized skin necrosis in 3 (2.2%), folliculitis in 3 (2.2%), and localized purulent complications in 2 (1.5%). Micro-air embolism of the pulmonary artery branches due to exceeding the established norm of air volume during foam sclerotherapy was recorded in 2 (2.9%) cases.Following one session, a positive sclerotherapy effect was noted in 45.9% of patients. The necessity for additional sclerotherapy courses was indicated for over half the patients, with the effectiveness rising to 97.8% after 3 or more courses.Conclusion. Sclerotherapy, being an effective minimally invasive method, is significantly impactful in treating reticular varices and telangiectasias. Greater efficiency and a lower rate of complications have been observed with the use of foam form sclerosant. Proper selection of sclerosant volume and concentration is essential for the prevention and reduction of sclerotherapy complications.","PeriodicalId":345517,"journal":{"name":"Health care of Tajikistan","volume":"15 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122666353","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-07-12DOI: 10.52888/0514-2515-2023-357-2-44-50
I. Ziyoratsho
Aim. To ascertain the diagnostic reliability of puncture and trepan biopsy of salivary gland tumors under ultrasound controlMaterials and Methods. The study included 26 patients diagnosed with benign tumors and 16 patients with malignant tumors of the salivary glands. To determine the final diagnosis, a cystology test was conducted using the Romanov Giemsa staining method on the materials. Histological examinations were stained using the hematoxylin-eosin technique.Results and Discussion. All 42 patients (100% of cases) with salivary gland tumors were divided into two groups based on the morphological features of their tumors: Group I comprised 20 patients (47.6% of cases) from a retrospective study conducted from 2013 to 2016, and Group II encompassed 22 patients (52.4% of cases) from a prospective study conducted from 2017 to 2020. Our uniquely developed method of puncture and trepan biopsy under ultrasound control demonstrated that the results derived from this approach closely aligned with those obtained from incisional and excisional biopsies. This correspondence underlines the successful diagnosis and treatment of patients with benign and malignant tumors of the salivary glands.Conclusion. The method of puncture and trepan-biopsy under ultrasound control exhibits high diagnostic reliability in confirming cells of benign and malignant tumors of the salivary glands, thereby eliminating the need for incisional and excisional biopsy of these tumors in subsequent treatment strategies. In Group I, the discrepancy between the investigative methods was 35%, while in Group II, which employed our method of puncture and trepan biopsy under ultrasound control, no inconsistency was observed.
{"title":"Diagnostic significance of puncture and trepan biopsy of salivary gland tumors under ultrasound control and its reliability in doubtful situations","authors":"I. Ziyoratsho","doi":"10.52888/0514-2515-2023-357-2-44-50","DOIUrl":"https://doi.org/10.52888/0514-2515-2023-357-2-44-50","url":null,"abstract":"Aim. To ascertain the diagnostic reliability of puncture and trepan biopsy of salivary gland tumors under ultrasound controlMaterials and Methods. The study included 26 patients diagnosed with benign tumors and 16 patients with malignant tumors of the salivary glands. To determine the final diagnosis, a cystology test was conducted using the Romanov Giemsa staining method on the materials. Histological examinations were stained using the hematoxylin-eosin technique.Results and Discussion. All 42 patients (100% of cases) with salivary gland tumors were divided into two groups based on the morphological features of their tumors: Group I comprised 20 patients (47.6% of cases) from a retrospective study conducted from 2013 to 2016, and Group II encompassed 22 patients (52.4% of cases) from a prospective study conducted from 2017 to 2020. Our uniquely developed method of puncture and trepan biopsy under ultrasound control demonstrated that the results derived from this approach closely aligned with those obtained from incisional and excisional biopsies. This correspondence underlines the successful diagnosis and treatment of patients with benign and malignant tumors of the salivary glands.Conclusion. The method of puncture and trepan-biopsy under ultrasound control exhibits high diagnostic reliability in confirming cells of benign and malignant tumors of the salivary glands, thereby eliminating the need for incisional and excisional biopsy of these tumors in subsequent treatment strategies. In Group I, the discrepancy between the investigative methods was 35%, while in Group II, which employed our method of puncture and trepan biopsy under ultrasound control, no inconsistency was observed.","PeriodicalId":345517,"journal":{"name":"Health care of Tajikistan","volume":"70 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125390988","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-07-12DOI: 10.52888/0514-2515-2023-357-2-69-76
F. Makhmadov, A. S. Ashurov, E. H. Tagoikulov
Aim. To examine the morphology of the liver in controlled obstructive jaundice in experimental animalsMaterials and Methods. This research was conducted through an experimental study involving 24 male Shingilla rabbits and 18 white rats of both sexes, all of which were maintained under identical conditions of care and diet. To establish a model of varying degrees of obstructive jaundice, the animals were divided into three groups. Group I comprised animals (n=8) which, following cholecystectomy and drainage of the choledochus, experienced a complete block of hepaticocholedochus within 48 hours. Group II (n=8) included animals wherein the block of hepaticocholedochus persisted for 48-60 hours, and Group III (n=8) involved animals experiencing more than 60 hours of hepaticocholedochus blockage.Results. Histological examination of liver biopsy specimens from the experimental animals revealed distinctive morphological changes in the parenchyma based on the duration of obstructive jaundice modeling, as compared to the liver of a healthy animal. In the pathohistological study of the Group I animals, liver micro-preparations displayed uneven color throughout the entire area of the sections, central vein expansion with altered shape, and traces of a small number of erythrocytes. Analysis of biopsy specimens from Groups II and III revealed irreversible dystrophic and necrotic processes in hepatocytes.Conclusion. Thus, experimental studies, premised on the modeling of controlled obstructive jaundice, revealed that complete blockage of the hepaticocholedochus, over varying time intervals, corresponded with hepatocyte damage, underpinned by escalating cholestatic processes.
{"title":"Liver morphology in regulated mechanical jaundice (experimental study)","authors":"F. Makhmadov, A. S. Ashurov, E. H. Tagoikulov","doi":"10.52888/0514-2515-2023-357-2-69-76","DOIUrl":"https://doi.org/10.52888/0514-2515-2023-357-2-69-76","url":null,"abstract":"Aim. To examine the morphology of the liver in controlled obstructive jaundice in experimental animalsMaterials and Methods. This research was conducted through an experimental study involving 24 male Shingilla rabbits and 18 white rats of both sexes, all of which were maintained under identical conditions of care and diet. To establish a model of varying degrees of obstructive jaundice, the animals were divided into three groups. Group I comprised animals (n=8) which, following cholecystectomy and drainage of the choledochus, experienced a complete block of hepaticocholedochus within 48 hours. Group II (n=8) included animals wherein the block of hepaticocholedochus persisted for 48-60 hours, and Group III (n=8) involved animals experiencing more than 60 hours of hepaticocholedochus blockage.Results. Histological examination of liver biopsy specimens from the experimental animals revealed distinctive morphological changes in the parenchyma based on the duration of obstructive jaundice modeling, as compared to the liver of a healthy animal. In the pathohistological study of the Group I animals, liver micro-preparations displayed uneven color throughout the entire area of the sections, central vein expansion with altered shape, and traces of a small number of erythrocytes. Analysis of biopsy specimens from Groups II and III revealed irreversible dystrophic and necrotic processes in hepatocytes.Conclusion. Thus, experimental studies, premised on the modeling of controlled obstructive jaundice, revealed that complete blockage of the hepaticocholedochus, over varying time intervals, corresponded with hepatocyte damage, underpinned by escalating cholestatic processes.","PeriodicalId":345517,"journal":{"name":"Health care of Tajikistan","volume":"18 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130636400","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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