Pub Date : 2022-07-22DOI: 10.52888/0514-2515-2022-353-2-113-120
D. Radjabov
This review of the literature presents current understanding about the etiology, pathogenesis, complications, contemporary methods of treatment, outcomes, and the tactics of managing patients with deep venous thrombosis (DVT) of the lower limbs. Analysis of the data in a literature shows that despite significant advances in the diagnosis and treatment of DVT of the lower extremities, there are still many unresolved problems in terms of complex treatment and prevention of severe consequences of this pathology. The advent of new oral anticoagulants has led to a significant reduction in the incidence of post-thrombotic disease. However, the severity of post-thrombotic disease directly depends on the effectiveness of treatment in acute period of DVT, as well as the presence of hereditary risk factors. In this regard, the optimization of therapy in acute phase of disease and further rehabilitation therapy, management of patients in the long-term period, aimed at better recanalization of thrombosed segments of the lower limbs deep veins, seem to be relevant, requiring further research.
{"title":"Some aspects of etiopathogenesis and treatment of the deep venous thrombosis of lower limbs","authors":"D. Radjabov","doi":"10.52888/0514-2515-2022-353-2-113-120","DOIUrl":"https://doi.org/10.52888/0514-2515-2022-353-2-113-120","url":null,"abstract":" This review of the literature presents current understanding about the etiology, pathogenesis, complications, contemporary methods of treatment, outcomes, and the tactics of managing patients with deep venous thrombosis (DVT) of the lower limbs. Analysis of the data in a literature shows that despite significant advances in the diagnosis and treatment of DVT of the lower extremities, there are still many unresolved problems in terms of complex treatment and prevention of severe consequences of this pathology. The advent of new oral anticoagulants has led to a significant reduction in the incidence of post-thrombotic disease. However, the severity of post-thrombotic disease directly depends on the effectiveness of treatment in acute period of DVT, as well as the presence of hereditary risk factors. In this regard, the optimization of therapy in acute phase of disease and further rehabilitation therapy, management of patients in the long-term period, aimed at better recanalization of thrombosed segments of the lower limbs deep veins, seem to be relevant, requiring further research.","PeriodicalId":345517,"journal":{"name":"Health care of Tajikistan","volume":"27 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129169673","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-07-22DOI: 10.52888/0514-2515-2022-353-2-105-109
S. Rasulov, A. A. Khudzhamkulov
A patient with complaints of difficult passage of solid food through the oesophagus, putrid breath, general weakness, a CT scan of the oesophagus revealed signs of a fistulous passage in the lower third of the oesophagus with a cavity in 9-10 segments of the right lung, with fluid resembling an abscess with perifocal infiltrative changes in lung tissue. Esophagogastroduodenoscopy revealed a diverticulum in the lower third of the esophagus with two fistulous passages into the pleural cavity. The patient underwent right thoracotomy to empty the abscess cavity, excision of the fibrous capsule of the abscess wall, excision of the diverticula and restoration of the esophageal wall integrity. A complication of oesophageal diverticula in the form of a fistula with formation of an abscess in the pleural cavity is a casuistic case. The main treatment for this complication is surgery.
{"title":"Surgical treatment of esophageal diverticula with a rare complication","authors":"S. Rasulov, A. A. Khudzhamkulov","doi":"10.52888/0514-2515-2022-353-2-105-109","DOIUrl":"https://doi.org/10.52888/0514-2515-2022-353-2-105-109","url":null,"abstract":" A patient with complaints of difficult passage of solid food through the oesophagus, putrid breath, general weakness, a CT scan of the oesophagus revealed signs of a fistulous passage in the lower third of the oesophagus with a cavity in 9-10 segments of the right lung, with fluid resembling an abscess with perifocal infiltrative changes in lung tissue. Esophagogastroduodenoscopy revealed a diverticulum in the lower third of the esophagus with two fistulous passages into the pleural cavity. The patient underwent right thoracotomy to empty the abscess cavity, excision of the fibrous capsule of the abscess wall, excision of the diverticula and restoration of the esophageal wall integrity. A complication of oesophageal diverticula in the form of a fistula with formation of an abscess in the pleural cavity is a casuistic case. The main treatment for this complication is surgery.","PeriodicalId":345517,"journal":{"name":"Health care of Tajikistan","volume":"42 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126650421","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-07-22DOI: 10.52888/0514-2515-2022-353-2-109-112
Z. Azizzoda, B. K. Khakimov, M. B. Sangov, A. T. Murodov, F. Safarov
The paper presents a case of the practice of diagnosis and surgical treatment of a 26-year-old woman with multiple liver echinococcosis. The diagnosis was established on the basis of ultrasound. The cyst in the left lobe located partially extreparenchymatous. An open drainage of the residual cavity was performed. According to intraoperative ultrasound data, there was also a second cyst located deep in the projection of VII and VIII segments with signs of suppuration. Due to the threat of massive bleeding and trauma to the liver tissue, it was decided to perform a transhepatic puncture of the cyst. Approximately 200 ml of thick pus was released. The cyst was dreined by echinococcectomy with «pig tail» 16Fr drainage. The postoperative period is also conservative complications. The patient was discharged on the 14 th day after surgery in Key multiple hydatid cysts.
{"title":"Combination of traditional open and perkutaneous-transhepatic echinococcectomy for multiple liver echinococcus cysts","authors":"Z. Azizzoda, B. K. Khakimov, M. B. Sangov, A. T. Murodov, F. Safarov","doi":"10.52888/0514-2515-2022-353-2-109-112","DOIUrl":"https://doi.org/10.52888/0514-2515-2022-353-2-109-112","url":null,"abstract":" The paper presents a case of the practice of diagnosis and surgical treatment of a 26-year-old woman with multiple liver echinococcosis. The diagnosis was established on the basis of ultrasound. The cyst in the left lobe located partially extreparenchymatous. An open drainage of the residual cavity was performed. According to intraoperative ultrasound data, there was also a second cyst located deep in the projection of VII and VIII segments with signs of suppuration. Due to the threat of massive bleeding and trauma to the liver tissue, it was decided to perform a transhepatic puncture of the cyst. Approximately 200 ml of thick pus was released. The cyst was dreined by echinococcectomy with «pig tail» 16Fr drainage. The postoperative period is also conservative complications. The patient was discharged on the 14 th day after surgery in Key multiple hydatid cysts.","PeriodicalId":345517,"journal":{"name":"Health care of Tajikistan","volume":"76 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123085943","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-07-21DOI: 10.52888/0514-2515-2022-353-2-88-93
Z. Tilloeva, B. P. Pirmakhmadzoda, A. K. Mahmadov, K. R. Safarov, A. M. Shokarimov, G. B. Sharvonova, S. Y. Bakhromova
Aim. To assess the informativeness and acceptability of the use of the annual reporting form No. 8 on tuberculosis in the Republic of Tajikistan. Materials and methods. This article studied the formation of the TB annual reporting form (form No. 8), assessment of dependence of TB indicators from TB annual reporting form in the Republic of Tajikistan. Results. The data indicate that the form of annual reporting on tuberculosis (form 8) cannot provide complete and reliable information about the incidence and prevalence of tuberculosis, does not note the migration processes inside of country and changing trends in the TB and DR TB epidemic which were calculated in the basis of Dushanbe data. Conclusion. The authors recommend to revise the annual reporting form on tuberculosis according to World Health Organization recommendation.
{"title":"Evaluation of the reporting of tuberculosis in Tajikistan","authors":"Z. Tilloeva, B. P. Pirmakhmadzoda, A. K. Mahmadov, K. R. Safarov, A. M. Shokarimov, G. B. Sharvonova, S. Y. Bakhromova","doi":"10.52888/0514-2515-2022-353-2-88-93","DOIUrl":"https://doi.org/10.52888/0514-2515-2022-353-2-88-93","url":null,"abstract":" Aim. To assess the informativeness and acceptability of the use of the annual reporting form No. 8 on tuberculosis in the Republic of Tajikistan. Materials and methods. This article studied the formation of the TB annual reporting form (form No. 8), assessment of dependence of TB indicators from TB annual reporting form in the Republic of Tajikistan. Results. The data indicate that the form of annual reporting on tuberculosis (form 8) cannot provide complete and reliable information about the incidence and prevalence of tuberculosis, does not note the migration processes inside of country and changing trends in the TB and DR TB epidemic which were calculated in the basis of Dushanbe data. Conclusion. The authors recommend to revise the annual reporting form on tuberculosis according to World Health Organization recommendation.","PeriodicalId":345517,"journal":{"name":"Health care of Tajikistan","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-07-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129849859","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-07-21DOI: 10.52888/0514-2515-2022-353-2-100-105
S. Yusuf, S. S. Jaborova, M. A. Khaidarova, S. Sattorov, Z. Sakipova
{"title":"Antioxidant activity of the roots of rhodiola multiflorum and the catnip herb in Tajikistan","authors":"S. Yusuf, S. S. Jaborova, M. A. Khaidarova, S. Sattorov, Z. Sakipova","doi":"10.52888/0514-2515-2022-353-2-100-105","DOIUrl":"https://doi.org/10.52888/0514-2515-2022-353-2-100-105","url":null,"abstract":"","PeriodicalId":345517,"journal":{"name":"Health care of Tajikistan","volume":"44 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-07-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131764595","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-07-21DOI: 10.52888/0514-2515-2022-353-2-60-67
H. S. Nazarov, S. Nazarov, N. Hasanov
Aim. To improve the results of surgical treatment of patients with acute intestinal obstruction of tumor genesis during radical surgery. Material and methods. Results of observation and treatment of 31 patients with acute colonic obstruction of tumorous genesis at the age from 34 till 72 years are presented. The most frequently observed was rectosigmoidal location of the tumor. The study group included 14 patients (45,2 %), in the control group - 17 (54,8 %). For diagnostic purposes general clinical and biochemical blood tests, ultrasound, MRI, CT, colonoscopy, rectoromonoscopy and video laparoscopy when indicated as well as pathohistological examination of biopsy specimens, taken from macro preparations of removed celiac tumor were carried out. Results and discussion. It was found out that more expressed decrease of inflammatory processes and intoxication indexes is observed in the patients of the main group, which were preoperatively prepared according to the method suggested in the clinic; early normalization of the laboratory and instrumental indexes in the postoperative period in comparison with the control group of patients, in which preoperative preparation was performed according to the traditional schemes. In 2 (11,8 %) cases of the control group patients suture inconsistency was revealed, in 3 (17,6 %) cases - purulence of the postoperative wound. In 1 case (5.9 %) lethal outcome was registered due to myocardial infarction. Inflammation of the postoperative wound was observed only in 1 (7,1 %) case among the main group patients. Conclusion. Decompression of the upper section of the bowel loop in combination to enterosorption in the preoperative period is the effective method of the bowel preparation for the radical surgery and promotes to decrease the frequency of the early postoperative purulent-inflammatory complications.
{"title":"Efficiency of pre-operative preparation of intestines at treatment of sharp intestinal impassability tumoral genesis","authors":"H. S. Nazarov, S. Nazarov, N. Hasanov","doi":"10.52888/0514-2515-2022-353-2-60-67","DOIUrl":"https://doi.org/10.52888/0514-2515-2022-353-2-60-67","url":null,"abstract":" Aim. To improve the results of surgical treatment of patients with acute intestinal obstruction of tumor genesis during radical surgery. Material and methods. Results of observation and treatment of 31 patients with acute colonic obstruction of tumorous genesis at the age from 34 till 72 years are presented. The most frequently observed was rectosigmoidal location of the tumor. The study group included 14 patients (45,2 %), in the control group - 17 (54,8 %). For diagnostic purposes general clinical and biochemical blood tests, ultrasound, MRI, CT, colonoscopy, rectoromonoscopy and video laparoscopy when indicated as well as pathohistological examination of biopsy specimens, taken from macro preparations of removed celiac tumor were carried out. Results and discussion. It was found out that more expressed decrease of inflammatory processes and intoxication indexes is observed in the patients of the main group, which were preoperatively prepared according to the method suggested in the clinic; early normalization of the laboratory and instrumental indexes in the postoperative period in comparison with the control group of patients, in which preoperative preparation was performed according to the traditional schemes. In 2 (11,8 %) cases of the control group patients suture inconsistency was revealed, in 3 (17,6 %) cases - purulence of the postoperative wound. In 1 case (5.9 %) lethal outcome was registered due to myocardial infarction. Inflammation of the postoperative wound was observed only in 1 (7,1 %) case among the main group patients. Conclusion. Decompression of the upper section of the bowel loop in combination to enterosorption in the preoperative period is the effective method of the bowel preparation for the radical surgery and promotes to decrease the frequency of the early postoperative purulent-inflammatory complications.","PeriodicalId":345517,"journal":{"name":"Health care of Tajikistan","volume":"9 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-07-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134258915","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-07-21DOI: 10.52888/0514-2515-2022-353-2-49-54
P. G. Kurbanova, E. I. Nazarov, A. V. Vohidov
Aim. To study the incidence of rachitis in children of Tajikistan. Materials and methods. The main methodology used in the analysis of the incidence of rickets was a retrospective study (conducted between 2009 and 2016), using descriptive and analytical methods of modern epidemiology. The mean value (M) and mean error (m) were calculated, and the annual average rate of increase and decrease (Tpr/dec, %) were calculated. The dynamic analysis of rachitis incidence rates covered a 7-year interval. Results. An analysis of the incidence of rickets over a 7-year period showed that in 2009 the incidence rate across the country was 40733.4 %, and in 2016 it decreased to 13500.9 %. The rate of decline for this period was 66.8 %, and the average annual rate of decline was 9.5 %. In 2009, the incidence rate among rural residents was 72990.2 % which is 1.6 times higher than in the city. After seven years, the incidence rate tended to decrease but remained 1.9 times higher than in the city. The highest rate of rickets was found among children 1 year of age. Conclusion. The highest incidence rate of rickets was found in in 2009 in GBAO , Dushanbe, and RRS. In these regions, the rate of decline in 2016 was also significant. The morbidity rate among children living in rural areas in the analyzed years tended to decrease by 3.9 % on average. The highest incidence rate of rickets was found among children of 1 year of age.
{"title":"Incidence of rachit in children of Tajikistan","authors":"P. G. Kurbanova, E. I. Nazarov, A. V. Vohidov","doi":"10.52888/0514-2515-2022-353-2-49-54","DOIUrl":"https://doi.org/10.52888/0514-2515-2022-353-2-49-54","url":null,"abstract":" Aim. To study the incidence of rachitis in children of Tajikistan. Materials and methods. The main methodology used in the analysis of the incidence of rickets was a retrospective study (conducted between 2009 and 2016), using descriptive and analytical methods of modern epidemiology. The mean value (M) and mean error (m) were calculated, and the annual average rate of increase and decrease (Tpr/dec, %) were calculated. The dynamic analysis of rachitis incidence rates covered a 7-year interval. Results. An analysis of the incidence of rickets over a 7-year period showed that in 2009 the incidence rate across the country was 40733.4 %, and in 2016 it decreased to 13500.9 %. The rate of decline for this period was 66.8 %, and the average annual rate of decline was 9.5 %. In 2009, the incidence rate among rural residents was 72990.2 % which is 1.6 times higher than in the city. After seven years, the incidence rate tended to decrease but remained 1.9 times higher than in the city. The highest rate of rickets was found among children 1 year of age. Conclusion. The highest incidence rate of rickets was found in in 2009 in GBAO , Dushanbe, and RRS. In these regions, the rate of decline in 2016 was also significant. The morbidity rate among children living in rural areas in the analyzed years tended to decrease by 3.9 % on average. The highest incidence rate of rickets was found among children of 1 year of age.","PeriodicalId":345517,"journal":{"name":"Health care of Tajikistan","volume":"19 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-07-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127639015","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-07-21DOI: 10.52888/0514-2515-2022-353-2-83-88
M. M. Rajabzoda
Aim. Improvement of the results of diagnostics and provision of pre- and hospital medical care to victims with concomitant and multiple trauma in road accidents. Material and research methods. Based on the analysis of the results of diagnosis and treatment, it was found that the Department of Traumatology and Orthopedics of the Regional Clinical Hospital named after B. Vohidov of the city of Bokhtar (former Kurgan-Tyube) for the period 2012 - 2020. there were 2120 patients with injuries. 1234 (58.2 %) victims were injured as a result of road accidents. Research results and their discussion. Prehospital care for victims with concomitant and multiple trauma:1) Pain relief through the use of non-narcotic and narcotic analgesics, aseptic dressings on wounds;2) Immobilizing position of the victim on the shield and stretcher for transportation;3) Introduction of cardiac and respiratory analeptics (strophanthin, korglikon, cordiamine); Conclusion. Thus, in the provision of emergency care to patients with concomitant and multiple trauma on the background of road traffic accidents, the following seems justified.1. Constantly train traffic police officers, drivers of passenger vehicles in the methods of providing first aid directly at the scene of the accident.2. Strengthen the personnel and material - technical potential of regional hospitals located on the highway.3. Improvement of diagnostic and treatment algorithms, training, regular discussion of tactical guidelines their possible correction.
{"title":"Consequences of road transportation accidents, their standard growth, modern management and tactics of treatment of victims","authors":"M. M. Rajabzoda","doi":"10.52888/0514-2515-2022-353-2-83-88","DOIUrl":"https://doi.org/10.52888/0514-2515-2022-353-2-83-88","url":null,"abstract":"Aim. Improvement of the results of diagnostics and provision of pre- and hospital medical care to victims with concomitant and multiple trauma in road accidents. Material and research methods. Based on the analysis of the results of diagnosis and treatment, it was found that the Department of Traumatology and Orthopedics of the Regional Clinical Hospital named after B. Vohidov of the city of Bokhtar (former Kurgan-Tyube) for the period 2012 - 2020. there were 2120 patients with injuries. 1234 (58.2 %) victims were injured as a result of road accidents. Research results and their discussion. Prehospital care for victims with concomitant and multiple trauma:1) Pain relief through the use of non-narcotic and narcotic analgesics, aseptic dressings on wounds;2) Immobilizing position of the victim on the shield and stretcher for transportation;3) Introduction of cardiac and respiratory analeptics (strophanthin, korglikon, cordiamine); Conclusion. Thus, in the provision of emergency care to patients with concomitant and multiple trauma on the background of road traffic accidents, the following seems justified.1. Constantly train traffic police officers, drivers of passenger vehicles in the methods of providing first aid directly at the scene of the accident.2. Strengthen the personnel and material - technical potential of regional hospitals located on the highway.3. Improvement of diagnostic and treatment algorithms, training, regular discussion of tactical guidelines their possible correction.","PeriodicalId":345517,"journal":{"name":"Health care of Tajikistan","volume":"63 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-07-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127703387","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-07-21DOI: 10.52888/0514-2515-2022-353-2-74-79
F. T. Nosirova, S. G. Umarzoda, M. M. Khodjieva
Aim. To evaluate the effectiveness of non-adjuvant polichemotherapy in the combined treatment of advanced ovarian cancer. Material and methods. The material for the study was the clinical data of the 238 patients who were examined and treated in the SI “Republic Oncology scientific center” of the MHSP of the RT with morphologically proved diagnosis of ovarian cancer. The average age of patients was 45,7 ± 0,92 years. Non-adjuvant polichemotherapy was performed in 64(27,9 %) patients: 61 patients with stage III and 3 patients with stage IV of the diseases. Perfomance status of patient was evaluated by EGOG scale (WHO). The effectiveness of non-adjuvant polichemotherapy to evaluate by clinical data (scale Registry for evaluate the effectiveness of the therapy solid tumors on 4 categories, recommended by EORTC&NCL,2000y. (data of recto-vaginal bimanual observation, ultrasound and markers of tumor until treatment and after 2 cycle of the polichemotherapy). Statistical methods included program SPSS 16.0 Results and discussion. As a result of non-adjuvant polichemotherapy, complete tumor regression was noted in 16(25 %) patients, portial tumor regression was noted in 20 (31,2 %) patients, stabilization was noted in 18(28,1 %) and progression was noted in 10 (15,6 %) patients. The overall objective effectiveness of non-adjuvant polichemotherapy was equal to 84,4 %. Conclusion. The overall objective effectiveness of non-adjuvant polichemotherapy was equal to 84,4 % and allowed the achievement of optimal surgery of 43,7 % patients. Disruption of the rhythm of chemotherapy treatment contributes to the decrease in frequency of optimal cytoreductive operations and affects the outcome of the disease.
{"title":"Non–adjuvant polichemotherapy for advanced ovarian cancer","authors":"F. T. Nosirova, S. G. Umarzoda, M. M. Khodjieva","doi":"10.52888/0514-2515-2022-353-2-74-79","DOIUrl":"https://doi.org/10.52888/0514-2515-2022-353-2-74-79","url":null,"abstract":" Aim. To evaluate the effectiveness of non-adjuvant polichemotherapy in the combined treatment of advanced ovarian cancer. Material and methods. The material for the study was the clinical data of the 238 patients who were examined and treated in the SI “Republic Oncology scientific center” of the MHSP of the RT with morphologically proved diagnosis of ovarian cancer. The average age of patients was 45,7 ± 0,92 years. Non-adjuvant polichemotherapy was performed in 64(27,9 %) patients: 61 patients with stage III and 3 patients with stage IV of the diseases. Perfomance status of patient was evaluated by EGOG scale (WHO). The effectiveness of non-adjuvant polichemotherapy to evaluate by clinical data (scale Registry for evaluate the effectiveness of the therapy solid tumors on 4 categories, recommended by EORTC&NCL,2000y. (data of recto-vaginal bimanual observation, ultrasound and markers of tumor until treatment and after 2 cycle of the polichemotherapy). Statistical methods included program SPSS 16.0 Results and discussion. As a result of non-adjuvant polichemotherapy, complete tumor regression was noted in 16(25 %) patients, portial tumor regression was noted in 20 (31,2 %) patients, stabilization was noted in 18(28,1 %) and progression was noted in 10 (15,6 %) patients. The overall objective effectiveness of non-adjuvant polichemotherapy was equal to 84,4 %. Conclusion. The overall objective effectiveness of non-adjuvant polichemotherapy was equal to 84,4 % and allowed the achievement of optimal surgery of 43,7 % patients. Disruption of the rhythm of chemotherapy treatment contributes to the decrease in frequency of optimal cytoreductive operations and affects the outcome of the disease.","PeriodicalId":345517,"journal":{"name":"Health care of Tajikistan","volume":"303 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-07-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"120943549","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-07-21DOI: 10.52888/0514-2515-2022-353-2-67-74
S. Nazarov, S. Ali-Zade, A. Ganiev, Sh. Anvarov
Aim. To optimize the surgical treatment of recurrent postoperative ventral hernias using synthetic alloplastic materials. Material and methods. The study was conducted among 139 patients with recurrent postoperative ventral hernias. According to the indications, all patients underwent abdominoplasty using mesh biologically inert alloprostheses using the “onlay” method and according to the original method with the displacement of the vaginal leaves mm. recti abdominis. Results and discussion. Recurrence of ventral hernias after the first year of follow-up was detected in 6 (4.3 %) patients. The causes of relapses in large hernias are dystrophic processes in the soft tissues of the anterior abdominal wall, caused both by the activation of fibroblasts upon contact with the polypropylene mesh, and directly by the defect of the mesh as a result of its rupture. In the event of a recurrence, reconstructive surgeries were performed in the scope of a modified technique with component separation to eliminate additional tissue tension. Conclusion. The developed method of surgical treatment of postoperative ventral hernias involves dissection of the anterior walls of the sheath of the rectus abdominis muscles along the the muscles, suturing the aponeurotic edges of the defect, connecting the rectus muscles along the midline, followed by fixing the mesh implant to the outer edges of the dissected aponeurosis of the rectus abdominis muscles, which makes it possible to prevent the occurrence of cicatricial degeneration and defect of functional activity, as demonstrated by monitoring the function of the rectus abdominis muscles.
{"title":"Functional alloplasty of recurrent postoperative hernias of the anterior abdominal wall","authors":"S. Nazarov, S. Ali-Zade, A. Ganiev, Sh. Anvarov","doi":"10.52888/0514-2515-2022-353-2-67-74","DOIUrl":"https://doi.org/10.52888/0514-2515-2022-353-2-67-74","url":null,"abstract":" Aim. To optimize the surgical treatment of recurrent postoperative ventral hernias using synthetic alloplastic materials. Material and methods. The study was conducted among 139 patients with recurrent postoperative ventral hernias. According to the indications, all patients underwent abdominoplasty using mesh biologically inert alloprostheses using the “onlay” method and according to the original method with the displacement of the vaginal leaves mm. recti abdominis. Results and discussion. Recurrence of ventral hernias after the first year of follow-up was detected in 6 (4.3 %) patients. The causes of relapses in large hernias are dystrophic processes in the soft tissues of the anterior abdominal wall, caused both by the activation of fibroblasts upon contact with the polypropylene mesh, and directly by the defect of the mesh as a result of its rupture. In the event of a recurrence, reconstructive surgeries were performed in the scope of a modified technique with component separation to eliminate additional tissue tension. Conclusion. The developed method of surgical treatment of postoperative ventral hernias involves dissection of the anterior walls of the sheath of the rectus abdominis muscles along the the muscles, suturing the aponeurotic edges of the defect, connecting the rectus muscles along the midline, followed by fixing the mesh implant to the outer edges of the dissected aponeurosis of the rectus abdominis muscles, which makes it possible to prevent the occurrence of cicatricial degeneration and defect of functional activity, as demonstrated by monitoring the function of the rectus abdominis muscles.","PeriodicalId":345517,"journal":{"name":"Health care of Tajikistan","volume":"2 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-07-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122976027","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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