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A systematized review aimed to identify the impact of basic electrocardiogram training courses on qualified nurses 一项系统的回顾,旨在确定基本心电图培训课程对合格护士的影响
Pub Date : 2018-10-01 DOI: 10.4103/SCCJ.SCCJ_2_19
F. Alanezi
Aims: A systematized review aimed to identify the impact of basic electrocardiogram (ECG) training courses on qualified nurses. Background: ECG plays a crucial role in helping to diagnose, follow-up, and detect any abnormalities in patients' conditions. Nurses often work on the frontline in hospitals and are the ones who initially assess patients' conditions. According to the British Heart Foundation (n. d), 26% of all mortality in the UK is attributable to heart and circulatory diseases. Methodology: A comprehensive, systematized review was undertaken using the AMED, EMBASE, CINAHL, and MEDLINE databases. Thematic analysis was then used to synthesis the findings from the studies selected. Ten papers were selected following the application of inclusion and exclusion criteria. Conclusion: Basic ECG training courses were found to improve nurses' knowledge, compared to those who did not possess ECG training, the quality of care was seen better among nurses who had received ECG courses, and even patient outcomes were improved in the total number of myocardial infarction events in hospital which was decreased compared to before the intervention. Cardiac care nurses had better ECG interpretation skills than other nurses regardless if they took ECG courses or not.
目的:一个系统化的回顾,旨在确定基本心电图(ECG)培训课程对合格护士的影响。背景:心电图在帮助诊断、随访和发现患者的任何异常情况方面起着至关重要的作用。护士通常在医院的第一线工作,是最初评估病人病情的人。根据英国心脏基金会(n. d)的数据,英国26%的死亡率可归因于心脏和循环系统疾病。方法:使用AMED、EMBASE、CINAHL和MEDLINE数据库进行全面、系统化的综述。然后使用主题分析来综合所选研究的结果。按照纳入和排除标准选择10篇论文。结论:基础心电培训课程提高了护士的知识水平,与未接受心电培训的护士相比,接受过心电培训课程的护士的护理质量更好,甚至患者的预后也有所改善,住院心肌梗死事件总数较干预前有所下降。无论是否参加过心电图课程,心内科护理护士的心电图解读能力均优于其他护理人员。
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引用次数: 4
Assessment of knowledge, attitude, and practice of hand hygiene among medical and health profession students at King Saud Bin Abdulaziz University for Health Sciences in Saudi Arabia 评估沙特阿拉伯沙特国王本阿卜杜勒阿齐兹健康科学大学医学和卫生专业学生的手卫生知识、态度和实践
Pub Date : 2018-10-01 DOI: 10.4103/SCCJ.SCCJ_6_19
Mohammed Humran, Khalid A Alahmary
Background: In recent years, patients' safety has become high priority for health-care organizations. It has been documented that poor knowledge and compliance of health-care providers toward hand hygiene have contributed to poor patient safety outcomes. College students of health sciences may not receive adequate education and training on hand hygiene best practices. Objectives: To assess the health profession students' knowledge, attitude, and practice toward hand hygiene and to investigate the factors associated with poor hand hygiene knowledge and practice. Methods: This cross-sectional, correlational, descriptive study was conducted at King Saud Bin Abdulaziz University for Health Sciences performing clinical rotations at King Abdulaziz Medical City in Riyadh, Saudi Arabia. A proportional sampling was used to calculate the required proportions that reflect the size of student population form each of the three colleges. A total of 270 students including 140 medical, 83 nursing, and 47 respiratory therapy students who were selected using a simple random sampling method were included in the study. An adapted and validated knowledge, attitude, and practice (KAP) questionnaire was used to assess four domains: general information, knowledge, self-reported compliance to the WHO 5 Moments of Hand Hygiene, and general satisfaction on received education. Results: The overall average of knowledge score was 81.13 points out of 100. The results revealed that the knowledge score of hand hygiene was higher for nursing school (84.22 ± 12.98), followed by medical school (81.71 ± 11.31) and then respiratory therapy program (75.53 ± 11.76). The results also showed that students who took courses covering hand hygiene scored higher in knowledge score (83.28 ± 11.3) as compared to students who did not take such courses (75.16 ± 12.89). In the compliance domain, the results showed that there were no significant differences in compliance of hand hygiene between students in all categories. In terms of overall student satisfaction with hand hygiene education and training, the results showed that nursing students have higher satisfaction score (72.7%) than their counterparts in medical school (48.3%) and respiratory therapy program (49.7%). Conclusion: Hand hygiene knowledge among students was generally good, and the highest was among nursing students and the lowest among respiratory therapy students. The compliance of students toward the WHO 5 Moments of Hand Hygiene did not vary across different colleges. Improved knowledge was found to be associated with improved compliance with hand hygiene best practices. Recommendations: Increasing the academic focus on hand hygiene in both the curriculum and clinical rotations with periodic standardized educational courses and focusing on hands-on workshops could have a positive impact on the knowledge and practice of hand hygiene for current health sciences students and future health-care providers. Future studies are needed t
背景:近年来,患者的安全已成为医疗机构的重中之重。有文件表明,卫生保健提供者对手卫生的认识不足和依从性差,导致患者安全结果不佳。健康科学专业的大学生可能没有得到关于手部卫生最佳做法的充分教育和培训。目的:了解卫生专业学生手卫生知识、态度和行为,探讨手卫生知识和行为不良的相关因素。方法:这项横断面、相关、描述性研究是在沙特阿拉伯利雅得阿卜杜勒阿齐兹国王医疗城进行临床轮转的沙特国王本阿卜杜勒阿齐兹健康科学大学进行的。采用比例抽样的方法来计算所需的比例,以反映这三所学院的学生人数。采用简单随机抽样的方法抽取270名学生,其中医学专业140名,护理专业83名,呼吸治疗专业47名。采用经过调整和验证的知识、态度和实践(KAP)问卷来评估四个领域:一般信息、知识、自我报告对世卫组织手部卫生五个时刻的遵守情况以及对接受教育的总体满意度。结果:知识总分平均为81.13分(满分100分)。结果显示,护理专业学生手卫生知识得分最高(84.22±12.98),其次是医学院(81.71±11.31),其次是呼吸治疗专业(75.53±11.76)。参加过手卫生课程的学生的知识得分(83.28±11.3)高于未参加过手卫生课程的学生(75.16±12.89)。依从性方面,各类别学生对手卫生的依从性均无显著差异。在学生对手卫生教育培训的总体满意度方面,护理专业学生的满意度为72.7%,高于医学院学生(48.3%)和呼吸治疗专业学生(49.7%)。结论:学生的手卫生知识水平普遍较好,其中护理专业学生的手卫生知识水平最高,呼吸治疗专业学生的手卫生知识水平最低。不同院校学生对WHO手部卫生五时刻的遵守情况没有差异。改进的知识被发现与更好地遵守手卫生最佳做法有关。建议:在课程和临床轮转中增加对手卫生的学术关注,定期举办标准化教育课程,并注重实践讲习班,可对当前卫生科学专业学生和未来卫生保健提供者的手卫生知识和实践产生积极影响。未来的研究需要通过实际实践的观察来评估医院学生的手卫生KAP。
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引用次数: 11
Role of point-of-care ultrasound to prevent dilatation of false passage in a critically ill patient with urethral stricture 急诊超声在预防重症尿道狭窄患者假通道扩张中的作用
Pub Date : 2018-10-01 DOI: 10.4103/SCCJ.SCCJ_29_18
D. Midha, A. Kumar, A. Mandal
Urethral strictures are fairly common in elderly males getting admitted to the intensive care unit. Urethral catheterization is mostly done as a blind procedure and often leads to urethral trauma and, sometimes, false channelization in a patient who is many a time sedated, intubated, and is unable to tell about extreme of pain occurring which could warn the handler. Fluoroscopy is utilized in difficult situations to aid insertion, but this is not always an option for patients in intensive care units. The scope of ultrasonography is expanding in the practice of critical care. We used point-of-care ultrasound to confirm the position of guidewire before dilatation, in order to prevent dilatation of false passage.
尿道狭窄在老年男性入住重症监护室是相当常见的。导尿通常是一种盲目的过程,经常导致尿道创伤,有时,患者在镇静、插管的情况下,无法说出发生的极端疼痛,这可能会警告处理者。在困难的情况下使用透视来辅助插入,但这并不总是重症监护病房患者的选择。超声检查在重症监护中的应用范围正在不断扩大。为了防止假通道扩张,我们在扩张前使用即时超声确认导丝的位置。
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引用次数: 0
Rare case of axillary pseudoaneurysm subsequent to an intra-arterial percutaneous cannulation 腋窝假性动脉瘤术后经皮动脉插管的罕见病例
Pub Date : 2018-07-01 DOI: 10.4103/SCCJ.SCCJ_26_18
A. Badeeb, Abdullah Taiyeb, J. Hudcova
Axillary pseudoaneurysm (PSA) is a rare condition that mainly presents with traumatic injury. In this case report, we show an iatrogenic axillary PSA, following an intra-arterial line (A-line) removal. A 75-year-old with an extensive past medical history including diabetes hypertension, peripheral vascular disease, and atrial fibrillation on Warfarin came to the hospital for an elective abdominal aortic aneurism repair. During her postsurgical stay, she had multiple A-line placements due to recurrent malfunctions and ended up having an axillary A-line. The development of a PSA complicated the removal of the line; an infrequent complication. This was treated with thrombin injection a couple of times after which homeostasis was achieved. Although axillary PSAs are rare, especially iatrogenic ones, individual attention and care should be taken while handling axillary A-lines. Furthermore, one should have a low level of suspicion, especially in patients with multiple predisposing risk factors such as ours.
腋窝假性动脉瘤是一种罕见的疾病,主要表现为外伤性损伤。在这个病例报告中,我们展示了一个医源性腋窝PSA,在动脉内线(a线)去除后。患者75岁,既往病史广泛,包括糖尿病、高血压、外周血管疾病和使用华法林治疗的心房颤动,前来医院进行选择性腹主动脉瘤修复。在她的术后住院期间,由于复发性故障,她进行了多次a线放置,最终获得了腋窝a线。PSA的发展使线路的移除变得复杂;罕见的并发症。用凝血酶注射治疗了几次,之后达到了体内平衡。虽然腋窝psa罕见,尤其是医源性psa,但在处理腋窝a线时应注意和小心。此外,一个人应该有低水平的怀疑,特别是在有多种易感危险因素的患者,如我们的。
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引用次数: 0
Essence of time in high altitude pulmonary edema – A case report 高原肺水肿的时间实质- 1例报告
Pub Date : 2018-07-01 DOI: 10.4103/SCCJ.SCCJ_31_18
U. Rathi, R. Gill, R. Saroa, Puja Saxena
High-altitude sickness can present with numerous symptoms ranging from headache, blurring of vision, dyspnea on exertion to more critical events such as pulmonary edema and cerebral edema. Rapid ascent, high altitudes of >2500 m, and previous lung disorders are the predisposing factors. Rapid and aggressive management forms the core treatment. Mechanical ventilation should be instituted at the earliest to prevent fatal consequences. Most of the cases are managed at medical centers at high altitudes only. Utmost coordination is required between centers for rapid management. Here, we report a case which was referred to our institute located at foothills with high-altitude pulmonary edema for intensive management.
高原反应可表现为多种症状,从头痛、视力模糊、运动时呼吸困难到更严重的事件,如肺水肿和脑水肿。快速上升、海拔> 2500m和既往肺部疾病是易感因素。快速和积极的管理形成了核心治疗。应尽早进行机械通气,防止发生致命后果。大多数病例只在高海拔地区的医疗中心进行治疗。为了快速管理,各中心之间需要最大程度的协调。在此,我们报告一例被转介到我们位于山麓的研究所的高海拔肺水肿进行强化治疗。
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引用次数: 0
A study of hand hygiene technique in intensive care unit of a tertiary care hospital 某三级医院重症监护病房手卫生技术研究
Pub Date : 2018-07-01 DOI: 10.4103/SCCJ.SCCJ_28_18
S. Vaya, J. Jeswani
Introduction: Hand hygiene (HH) has been characterized as the keystone and starting point in all infection control programs, with the hands of health-care faculty being the handler and advocates of infection in critically ill patients. Materials and Methods: This was a cross-sectional observational study using direct observation technique. A single observer collected all HH data. This single-observer study was conducted in the 45-bedded intensive care unit (ICU) of Mahatma Gandhi Hospital. HH compliance was monitored using the hand hygiene observation form developed by the World Health Organization. A nonidentified observer was used for monitoring compliance with HH. Results and Discussion: A total of 900 observations were recorded from health-care personnel in ICU. With respect to the personnel, the nursing department had the highest number of observations as 400 circulating nurses were sampled. There were also 110 senior consultants, 250 resident doctors, and 140 paramedical staffs. Of the total opportunities, nurses had the highest number of contacts (67%), followed by allied health-care workers (82.94%). The average compliance was about 75%, which differed significantly among health-care workers, with higher compliance among the nursing staff (82.9%) followed by allied staff (67%). Of the average overall compliance of 75%, maximum compliance was seen for moment 3, that is, the staffs were very careful after body fluid contact as it was perceived important for self-protection. The HH instances after patient contact (86.29%) also suggested similarly. The nurses' compliance was 64.40% before patient contact and 68.35% after touching surroundings. Conclusion: The observance of HH is still low in our local environment. Handwashing practices in our study show that health-care workers pay attention to HH, when it appears, there is a direct observable threat to their well-being. Educational programs need to be developed to address the issue of poor HH.
手部卫生(HH)被认为是所有感染控制项目的基石和起点,卫生保健教师的手是重症患者感染的处理者和倡导者。材料和方法:采用直接观察技术进行横断面观察研究。一个观察者收集所有HH数据。这项单观察者研究是在圣雄甘地医院45个床位的重症监护病房(ICU)进行的。使用世界卫生组织制定的手部卫生观察表监测卫生遵守情况。一名身份不明的观察员被用来监测HH的依从性。结果和讨论:共记录了900例来自ICU医护人员的观察结果。在人员方面,护理部门的观察人数最多,抽样了400名流动护士。还有110名高级顾问、250名住院医生和140名辅助医务人员。在所有接触机会中,护士接触次数最多(67%),其次是专职卫生保健工作者(82.94%)。平均依从性约为75%,卫生保健工作者的差异显著,护理人员的依从性最高(82.9%),其次是专职人员(67%)。在75%的平均总体依从性中,最大的依从性出现在第3时刻,即工作人员在接触体液后非常小心,因为这被认为对自我保护很重要。患者接触后的HH病例(86.29%)也有类似情况。护士在接触患者前和接触环境后的依从性分别为64.40%和68.35%。结论:在我国当地环境中,对HH的遵守程度仍然较低。我们的研究表明,卫生保健工作者注意洗手,当它出现时,对他们的健康有直接可观察到的威胁。需要制定教育方案来解决贫困儿童的问题。
{"title":"A study of hand hygiene technique in intensive care unit of a tertiary care hospital","authors":"S. Vaya, J. Jeswani","doi":"10.4103/SCCJ.SCCJ_28_18","DOIUrl":"https://doi.org/10.4103/SCCJ.SCCJ_28_18","url":null,"abstract":"Introduction: Hand hygiene (HH) has been characterized as the keystone and starting point in all infection control programs, with the hands of health-care faculty being the handler and advocates of infection in critically ill patients. Materials and Methods: This was a cross-sectional observational study using direct observation technique. A single observer collected all HH data. This single-observer study was conducted in the 45-bedded intensive care unit (ICU) of Mahatma Gandhi Hospital. HH compliance was monitored using the hand hygiene observation form developed by the World Health Organization. A nonidentified observer was used for monitoring compliance with HH. Results and Discussion: A total of 900 observations were recorded from health-care personnel in ICU. With respect to the personnel, the nursing department had the highest number of observations as 400 circulating nurses were sampled. There were also 110 senior consultants, 250 resident doctors, and 140 paramedical staffs. Of the total opportunities, nurses had the highest number of contacts (67%), followed by allied health-care workers (82.94%). The average compliance was about 75%, which differed significantly among health-care workers, with higher compliance among the nursing staff (82.9%) followed by allied staff (67%). Of the average overall compliance of 75%, maximum compliance was seen for moment 3, that is, the staffs were very careful after body fluid contact as it was perceived important for self-protection. The HH instances after patient contact (86.29%) also suggested similarly. The nurses' compliance was 64.40% before patient contact and 68.35% after touching surroundings. Conclusion: The observance of HH is still low in our local environment. Handwashing practices in our study show that health-care workers pay attention to HH, when it appears, there is a direct observable threat to their well-being. Educational programs need to be developed to address the issue of poor HH.","PeriodicalId":345799,"journal":{"name":"Saudi Critical Care Journal","volume":"506 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124463042","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Building capacity in critical care research coordination in Saudi Arabia: The role of the Saudi critical care trials group 沙特阿拉伯重症监护研究协调能力建设:沙特重症监护试验组的作用
Pub Date : 2018-07-01 DOI: 10.4103/SCCJ.SCCJ_30_18
A. Deeb, E. Al Qasim, Lara Y. Afesh, S. Abdukahil, M. Sadat, Y. Arabi
Critical care research is growing around the world including Saudi Arabia. The objective of this review is to discuss the building capacity in critical care research coordination in Saudi Arabia as a part of the research strategy of the Saudi Critical Care Trials Group (SCCTG). The SCCTG was developed to promote high impact critical care research in Saudi Arabia and to facilitate collaboration in national and international clinical research. Well-organized coordination between all parties is necessary by the presence of qualified clinical research coordinator (CRC). Critical care has unique features that make clinical research conduct more complex and demanding. It is a high-risk area with increased potentiality of error or adverse events occurrence. Critical care providers such as critical care nurses, critical care pharmacists, respiratory therapists, critical care physiotherapists, or intensive care unit physicians with added skills may be appropriate candidates to handle CRC roles in critical care setting. These skills include but not limited to data collection, obtaining consent, patient assessment, patient screening for the study eligibility, data entry, ethics submissions, providing teaching regarding the study protocol and research topics to clinical staff, attending to regulatory requirements, and designing data collection tools. The SCCTG shall focus on training the clinical research coordination skills through providing specialized courses and workshops that enable different hospitals to conduct and participate in clinical research. It will also help developing network group to connect critical care CRCs in Saudi Arabia and worldwide.
包括沙特阿拉伯在内的世界各地都在进行重症监护研究。本综述的目的是讨论沙特阿拉伯重症监护研究协调能力建设,作为沙特重症监护试验组(SCCTG)研究战略的一部分。制定SCCTG是为了促进沙特阿拉伯的高影响力重症监护研究,并促进国家和国际临床研究方面的合作。通过合格的临床研究协调员(CRC)的存在,各方之间组织良好的协调是必要的。重症监护具有独特的特点,使临床研究更加复杂和苛刻。这是一个高风险区域,发生错误或不良事件的可能性增加。重症监护提供者,如重症监护护士、重症监护药剂师、呼吸治疗师、重症监护物理治疗师或重症监护病房医生,具有额外技能,可能是在重症监护环境中处理结直肠癌角色的合适人选。这些技能包括但不限于数据收集、获得同意、患者评估、患者筛选研究资格、数据录入、伦理提交、向临床工作人员提供有关研究方案和研究主题的教学、遵守监管要求以及设计数据收集工具。SCCTG应重点培训临床研究协调技能,通过开设专业课程和讲习班,使不同医院能够开展和参与临床研究。它还将帮助建立网络小组,以连接沙特阿拉伯和世界各地的重症监护中心。
{"title":"Building capacity in critical care research coordination in Saudi Arabia: The role of the Saudi critical care trials group","authors":"A. Deeb, E. Al Qasim, Lara Y. Afesh, S. Abdukahil, M. Sadat, Y. Arabi","doi":"10.4103/SCCJ.SCCJ_30_18","DOIUrl":"https://doi.org/10.4103/SCCJ.SCCJ_30_18","url":null,"abstract":"Critical care research is growing around the world including Saudi Arabia. The objective of this review is to discuss the building capacity in critical care research coordination in Saudi Arabia as a part of the research strategy of the Saudi Critical Care Trials Group (SCCTG). The SCCTG was developed to promote high impact critical care research in Saudi Arabia and to facilitate collaboration in national and international clinical research. Well-organized coordination between all parties is necessary by the presence of qualified clinical research coordinator (CRC). Critical care has unique features that make clinical research conduct more complex and demanding. It is a high-risk area with increased potentiality of error or adverse events occurrence. Critical care providers such as critical care nurses, critical care pharmacists, respiratory therapists, critical care physiotherapists, or intensive care unit physicians with added skills may be appropriate candidates to handle CRC roles in critical care setting. These skills include but not limited to data collection, obtaining consent, patient assessment, patient screening for the study eligibility, data entry, ethics submissions, providing teaching regarding the study protocol and research topics to clinical staff, attending to regulatory requirements, and designing data collection tools. The SCCTG shall focus on training the clinical research coordination skills through providing specialized courses and workshops that enable different hospitals to conduct and participate in clinical research. It will also help developing network group to connect critical care CRCs in Saudi Arabia and worldwide.","PeriodicalId":345799,"journal":{"name":"Saudi Critical Care Journal","volume":"17 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121456647","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Euglycemic diabetic ketoacidosis caused by canagliflozin: A rare case report 卡格列净致糖尿病酮症酸中毒1例
Pub Date : 2018-04-01 DOI: 10.4103/SCCJ.SCCJ_20_18
Rupali Lahoria, S. Pandove, D. Bhasin, Harpal Singh, Surinder Singh, Rajit Jhingan
Drugs are one of the rare precipitating factors for diabetic ketoacidosis (DKA) in diabetes mellitus. Medications causing DKA are corticosteroids, pentamidine, clozapine, etc. Even rare is for an oral hypoglycemic agent to cause DKA, but since the approval of the first-in-class drug in 2013, data have emerged suggesting that sodium glucose transporter-2 inhibitors, including canagliflozin, may lead to DKA. This is a case of a 46-year-old male patient who was admitted to the intensive care unit with signs and symptoms suggestive of DKA. He was recently started on canagliflozin. He had a blood glucose level of 243 mg/dl, urine was positive for ketones, and his arterial blood gas was suggestive of high anion gap metabolic acidosis. All the precipitating causes of DKA were ruled out. Based on the above findings and laboratory results, the possibility of canagliflozin-induced ketoacidosis was kept and managed on the lines of DKA.
药物是糖尿病酮症酸中毒的罕见诱发因素之一。引起DKA的药物有皮质类固醇、喷他脒、氯氮平等。口服降糖药引起DKA的情况甚至很罕见,但自2013年首个同类药物获批以来,有数据表明,钠葡萄糖转运蛋白-2抑制剂,包括canagliflozin,可能导致DKA。这是一例46岁男性患者,因提示DKA的体征和症状而入住重症监护病房。他最近开始服用卡格列净。血糖243mg /dl,尿酮阳性,动脉血气提示高阴离子间隙代谢性酸中毒。所有诱发DKA的原因均已排除。基于上述发现和实验室结果,保持卡格列净诱导酮症酸中毒的可能性,并在DKA线上进行管理。
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引用次数: 0
Analysis of emergency laboratory parameters of various poisonings in tertiary care teaching hospital 三级教学医院各种中毒事件应急实验室参数分析
Pub Date : 2018-04-01 DOI: 10.4103/SCCJ.SCCJ_13_18
Raghu Kondle, D. Madhusudana, P. Shreevani, G. Reddy
Aim: India is predominantly an agricultural country; pesticides and insecticides are abundantly used during cultivation. The adult mortality rate due to mixed drug poisoning in rural south India is 0.97/1000 persons/year. Only 70%–80% of patients admitted to hospitals survive. The present study is undertaken to identifying the association of laboratory parameters with different poisoning etiologies which may help in predicting the need for ventilator support to reduce the mortality by timely entry into emergency department (ED). Materials and Methods: A prospective study on the mixed poisoning of 964 cases was done in the ED at Narayana Medical College Hospital, Nellore, Andhra Pradesh, for 8 years (from 2009 to Jan 2016). Clinical and laboratory data were recorded for all patients on admission (time 0) and 24 h later (time 24). The severity of patients graded according to the Glasgow Coma Scale (GCS) classification. Results: Among 964 patients, in the present study, the majority of the patients in the study group were males, and higher age group affected was 40–50 years. Agricultural farmers and rural residents were highly consumed pesticides. In the study, ingestion poisoning 95% had common occurrences than inhalation poisoning 5%. In severity categorization, we observed that 28.4% of patients were in mild condition, 55.6% in moderate, and 16% in severe. Mean, GCS scoring system was statistically significant between time 0 and time 24 in the survivors. Low GCS at admission was vulnerable for ventilator support. Cholinesterase activity was measured significantly depressed in the Grade 1, 2, and 3. Conclusions: The present study concludes that the need for ventilatory support in organophosphoros poisoning was significantly more in patients who consumed chlorpyrifos methyl parathion compounds, airway edema secondary to hair dye poisoning, presence of cholinergic crisis, GCS score of <6, and cardiovascular collapse secondary to aluminum poisoning.
目标:印度是一个主要的农业国家;在耕作过程中大量使用农药和杀虫剂。印度南部农村地区因混合药物中毒造成的成人死亡率为0.97/1000人/年。入院的病人中只有70%-80%能活下来。本研究旨在确定实验室参数与不同中毒病因的关系,这可能有助于预测是否需要呼吸机支持,以减少及时进入急诊科(ED)的死亡率。材料与方法:对2009年至2016年1月8年间安得拉邦内洛尔纳拉亚纳医学院附属医院急诊科964例混合性中毒病例进行前瞻性研究。记录所有患者入院时(时间0)和24小时后(时间24)的临床和实验室数据。患者的严重程度根据格拉斯哥昏迷量表(GCS)分级。结果:本研究964例患者中,研究组患者以男性居多,较高发病年龄组为40-50岁。农民和农村居民是农药的高消费人群。研究中,食入性中毒发生率为95%,而吸入性中毒发生率为5%。在严重程度分类中,我们观察到28.4%的患者为轻度,55.6%为中度,16%为重度。平均而言,GCS评分系统在时间0和时间24之间在幸存者中具有统计学意义。入院时GCS较低,易使用呼吸机支持。胆碱酯酶活性在1级、2级和3级显著降低。结论:本研究认为,有机磷中毒后使用甲基对硫磷毒死蜱化合物、染发剂中毒继发气道水肿、存在胆碱能危像、GCS评分<6、铝中毒继发心血管衰竭的患者对通气支持的需求明显增加。
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引用次数: 0
Low-dose imatinib mesylate causing subdural hematoma in remission phase of chronic myeloid leukemia: A rare phenomenon 低剂量甲磺酸伊马替尼引起慢性髓性白血病缓解期硬膜下血肿:罕见现象
Pub Date : 2018-04-01 DOI: 10.4103/SCCJ.SCCJ_19_18
V. Mishra, R. Singh, Souvik Chaudhuri, M. Sinha
Chronic subdural hematoma (SDH) is associated with trauma, antiplatelet therapy, anticoagulant medications, long-term alcohol abuse, arteriovenous malformations, and even postcraniotomy. However, SDH associated with imatinib mesylate (IM) treatment for chronic myeloid leukemia (CML) is rare that too in the remission phase of CML is even rarer. Among the cases of CML in remission phase, the literature review of those with SDH revealed that IM was taken in a dose of 800 mg per day. We report a case of SDH in a 70-year-old gentleman who was in the chronic remission phase of CML and was treated with IM 400 mg per day by hematologist.
慢性硬膜下血肿(SDH)与创伤、抗血小板治疗、抗凝药物、长期酒精滥用、动静脉畸形甚至开颅后有关。然而,SDH与甲酸伊马替尼(IM)治疗慢性髓性白血病(CML)相关的情况很少见,在CML缓解期更是罕见。在缓解期的CML病例中,SDH患者的文献综述显示IM的剂量为每天800 mg。我们报告一例SDH在一个70岁的绅士谁是慢性缓解期的慢性粒细胞白血病和治疗的IM 400mg /天由血液学家。
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引用次数: 0
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Saudi Critical Care Journal
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