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Delayed detection of esophageal intubation: Nasogastric tube was the cause? 食管插管延迟发现:鼻胃管是原因吗?
Pub Date : 2018-04-01 DOI: 10.4103/SCCJ.SCCJ_22_18
Neeraj Kumar, Amarjeet Kumar, P. Dubey, Sanjeev Kumar
Unrecognized misplacement of the endotracheal tube (ETT) during endotracheal intubation and ventilation, has a reported incidence of 2.9%–16.7% and is a frequent cause of morbidity and mortality in emergency intubations. Accidental esophageal intubation is a common mistake in inexperienced anesthetists, but unrecognized esophageal intubation is, fortunately, a rare event because, in anesthetic malpractice claims, it frequently resulted in death or brain damage. The most common factors contributing to delayed detection were not using, ignoring, or misinterpreting CO2 readings.
据报道,在气管插管和通气过程中,气管插管(ETT)未被识别的错位发生率为2.9%-16.7%,是急诊插管中发病率和死亡率的常见原因。在没有经验的麻醉师中,意外的食管插管是一个常见的错误,但幸运的是,未被识别的食管插管是一个罕见的事件,因为在麻醉事故索赔中,它经常导致死亡或脑损伤。导致检测延迟的最常见因素是不使用、忽略或误解二氧化碳读数。
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引用次数: 1
Spontaneous rupture of the stomach in nonneonatal period 非新生儿期自发性胃破裂
Pub Date : 2018-01-01 DOI: 10.4103/SCCJ.SCCJ_17_18
V. Mišanović, E. Begić
This study aimed to show the spontaneous rupture of the stomach in a 3-year-old girl. The patient was admitted to the pediatric clinic due to poor general condition that occurred suddenly with severe abdominal pain, vomiting, and the development of hypovolemic shock (blood pressure was unmeasurable, in acidosis), and after the ultrasound and abdominal X-ray, she was operated by the pediatric surgeon within 6 h of admission. During surgery, multiple defects of stomach mucosa with transmural bleeding without pathohistological changes in the muscle layer were found in the large stomach blood vessels. Treatment was continued in the pediatric intensive care unit with the development of life-limiting complications: peritonitis, sepsis, intracranial hemorrhage, and outcome of death. Rupture of the stomach caused by acute distension is rarely seen outside the neonatal period with fast clinical course and high mortality rate. Early diagnosis and rapid surgical procedures are a prerequisite to avoid the development of life-limiting complications that lead to a fatal outcome.
这项研究旨在展示一名3岁女孩的自发性胃破裂。患者因全身状况不佳,突然出现剧烈腹痛、呕吐,并发低血容量性休克(血压无法测量,呈酸中毒),入院后6小时内由儿科外科医生行手术。术中发现胃大血管多处胃黏膜缺损伴跨壁出血,肌层无病理组织学改变。在儿童重症监护病房继续治疗,出现限制生命的并发症:腹膜炎、败血症、颅内出血和死亡。急性胃胀引起的胃破裂在新生儿期以外罕见,临床病程快,死亡率高。早期诊断和快速的外科手术是避免发展导致致命结果的限制生命的并发症的先决条件。
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引用次数: 0
Tetanus and its continuing menace in the developing world: Critical care management 破伤风及其在发展中国家的持续威胁:重症监护管理
Pub Date : 2018-01-01 DOI: 10.4103/SCCJ.SCCJ_4_18
U. Hariharan, Swaraj Jyoti Sonowal, Ranvinder Kaur, Lalita Chaudhary
Tetanus, also known as lockjaw, is an infection characterized by muscle spasms. In the most common type, the spasms begin in the jaw and then progress to the rest of the body. These spasms usually last a few minutes each time and occur frequently for three to four weeks. Tetanus is a disease caused by the toxin produced by the ubiquitous bacterium, Clostridium tetani. C tetani infection can be acquired through surgery, intravenous drug abuse, the neonate's umbilicus, bites, burns, body piercing, puncture wounds, and ear infections. This organism can enter through any break in the integrity of the body. We hereby describe the successful management, including critical care challenges of a case of Tetanus in a young male patient following a minor toe injury. Timely airway management followed by early tracheostomy with effective control of muscle spasms and other supportive therapy is highlighted. Tetanus continues to be a menacing infectious disease with high fatality in the developing world.
破伤风,也被称为lockjaw,是一种以肌肉痉挛为特征的感染。在最常见的类型中,痉挛从下巴开始,然后发展到身体的其他部位。这些痉挛通常每次持续几分钟,经常发生三到四周。破伤风是一种由无处不在的细菌——破伤风梭菌产生的毒素引起的疾病。破伤风可通过手术、静脉药物滥用、新生儿脐部、咬伤、烧伤、身体穿刺、穿刺伤口和耳部感染获得。这种生物可以通过身体完整性的任何破坏进入。我们在此描述成功的管理,包括在一个年轻的男性病人轻微脚趾受伤破伤风病例的重症监护挑战。强调及时气道管理,早期气管切开术,有效控制肌肉痉挛和其他支持治疗。破伤风在发展中世界仍然是一种致命的传染病,死亡率很高。
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引用次数: 0
Phosphate-induced hypocalcemia may have a role to play in a patient of recurrent cardiac arrest with severe hypophosphatemia 磷酸盐诱导的低钙血症可能在复发性心脏骤停伴严重低磷血症患者中起作用
Pub Date : 2018-01-01 DOI: 10.4103/SCCJ.SCCJ_12_18
M. Jabbar, A. Sardar
Hypophosphatemia is a common electrolyte abnormality in our day-to-day practice in Intensive Care Unit. Severe hypophosphatemia is usually multifactorial and can lead to devastating consequences such as cardiac arrest. Phosphate replacement can be considered in severe symptomatic hypophosphatemia. We describe a patient of chronic alcoholic and diabetic who presented with diabetic ketoacidosis, right-lung pneumonia, and septic shock. Subsequently, the patient developed recurrent cardiac arrest. Both hypophosphatemia and phosphate-induced hypocalcemia were attributed to be the cause of this recurrent cardiac arrest.
低磷血症是我们在重症监护病房的日常实践中常见的电解质异常。严重的低磷血症通常是多因素的,可导致心脏骤停等破坏性后果。在严重的症状性低磷血症中可以考虑磷酸盐替代。我们描述了一个慢性酒精和糖尿病患者谁提出糖尿病酮症酸中毒,右肺肺炎和感染性休克。随后,患者再次出现心脏骤停。低磷血症和磷酸盐诱导的低钙血症都被认为是这种复发性心脏骤停的原因。
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引用次数: 2
A rare case of common krait envenomation presented with locked-in syndrome masquerading as brain death 常见的krait中毒的一个罕见的情况下提出闭锁综合征伪装成脑死亡
Pub Date : 2018-01-01 DOI: 10.4103/sccj.sccj_15_18
Dhruvkumar M. Patel, Mukundkumar V. Patel, Rajesh Mishra, Greshaben R. Patel
Krait (elapid snake) bite may be painless, without evidence of flange marks, and the patient is many times unaware of the bite. This may present as unexplained neuroparalysis and deep coma with absent brainstem reflexes, and it may look like brain death. We present a case of such unexplained neuroparalysis who was diagnosed on clinical ground, and the patient was completely recovered with anti-snake venom (ASV) and supportive treatment. A high index of suspicious, background history of the patient and timely empirical ASV therapy can save the patient from a coma with unexplained neuroparalysis from definite death.
Krait (elapapsnake)咬伤可能是无痛的,没有法兰痕迹的证据,病人很多时候都没有意识到咬伤。这可能表现为不明原因的神经麻痹和脑干反射缺失的深度昏迷,并可能看起来像脑死亡。我们报告一例这种不明原因的神经麻痹,经临床诊断,患者经抗蛇毒(ASV)和支持治疗后完全康复。高度可疑的患者背景病史和及时的经验ASV治疗可以使患者免于昏迷并不明原因的神经麻痹而确定死亡。
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引用次数: 3
Pressure ulcers in critically III patients in Saudi Arabia: An opportunity for collaborative research on an ugly disease 沙特阿拉伯III期重症患者的压疮:对一种丑陋疾病进行合作研究的机会
Pub Date : 2017-11-01 DOI: 10.4103/SCCJ.SCCJ_24_17
H. Al-Dorzi
Pressure ulcers are common in critically ill patients and are associated with increased morbidity, mortality and cost. Studies on pressure ulcer prevention and management indicate the need for multifaceted care and multidisciplinary involvement. However, there are obvious deficits in pressure ulcer prevention efforts and care worldwide. Studies on pressure ulcers acquired in the intensive care unit (ICU) in Saudi Arabia are scarce. We propose a study to determine in Saudi ICUs pressure ulcer prevalence, risk factors, management and outcomes to improve the related care processes.
压疮在危重病人中很常见,并与发病率、死亡率和费用增加有关。压疮预防和管理的研究表明,需要多方面的护理和多学科的参与。然而,在世界范围内,压疮的预防工作和护理存在明显的缺陷。在沙特阿拉伯的重症监护病房(ICU)获得的压疮研究很少。我们提出了一项研究,以确定在沙特icu压疮患病率,危险因素,管理和结果,以改善相关的护理过程。
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引用次数: 2
The cuff leak test prior to extubation: A practice based on limited evidence 拔管前袖带泄漏试验:基于有限证据的实践
Pub Date : 2017-11-01 DOI: 10.4103/SCCJ.SCCJ_27_17
K. Lewis, W. Alhazzani
Endotracheal intubation and mechanical ventilation are lifesaving interventions that are commonly performed in the intensive care unit (ICU). The trauma of endotracheal intubation itself, the prolongued pressure exerted by the endotracheal tube on the larynx, and miscellaneous factors such as fluid overload can result in laryngeal edema (LE). Extubation of a patient with undiagnosed LE can results in respiratory failure secondary to an upper airway obstruction and may require reintubation. Respiratory failure requiring reintubation is associated with morbidity and mortality. The cuff leak test (CLT) is the only method intensivists use to predict the presence of LE. Despite the CLT's first description in 1988, the correct way to interpret the results (either qualitatively or quantitatively) is unknown, and its diagnostic accuracy has been called into question. In fact, the CLT could be detrimental to patients if it has a high false positive rate (i.e. no air leak is detected indicating LE when none actually exists). Incorrectly diagnosing patients with LE may result in prolongued mechanical ventilation that predisposes patients to barotrauma, ventilator-associated infections, exposure to systemic steroids, and a prolongued stay in the ICU. Given the paucity of data, the Cuff Leak and Airway Obstruction in Mechanically Ventilated ICU Patients (COMIC) research group is conducting a survey to understand international practice surround the use of the CLT prior to extubation, as well as a randomized controlled trial that will capture the accuracy of the test and determine the bet method to measure cuff leak.
气管插管和机械通气是通常在重症监护病房(ICU)进行的救命干预措施。气管插管本身的创伤、气管插管对喉部施加的长期压力以及液体过载等多种因素均可导致喉部水肿。未确诊的LE患者拔管可导致继发于上气道阻塞的呼吸衰竭,并可能需要重新插管。需要重新插管的呼吸衰竭与发病率和死亡率相关。袖带泄漏试验(CLT)是唯一的方法,强化医生使用来预测LE的存在。尽管CLT于1988年首次描述,但解释结果(定性或定量)的正确方法尚不清楚,其诊断准确性也受到质疑。事实上,如果CLT有很高的假阳性率(即没有检测到空气泄漏,表明实际上没有LE),则CLT可能对患者有害。对LE患者的错误诊断可能导致延长机械通气时间,使患者容易遭受气压创伤、呼吸机相关感染、暴露于全身类固醇,并延长在ICU的住院时间。鉴于数据的缺乏,机械通气ICU患者袖带泄漏和气道阻塞(COMIC)研究小组正在进行一项调查,以了解拔管前使用CLT的国际惯例,以及一项随机对照试验,以获取测试的准确性并确定测量袖带泄漏的最佳方法。
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引用次数: 4
The bacteremia antibiotic length actually needed for clinical effectiveness research program (balance.ccctg.ca) 临床有效性研究项目实际需要的菌血症抗生素长度(balance.ccctg.ca)
Pub Date : 2017-11-01 DOI: 10.4103/2543-1854.219135
N. Daneman, Asgar Rishu, R. Fowler
A multitude of global health organizations have declared antimicrobial resistance a threat to health, based on rapidly increasing resistance rates and declining new drug development. Up to 30%–50% of antibiotic use is estimated to be inappropriate, and excessive durations of treatment are the greatest contributor to inappropriate use. A landmark trial in critically ill patients with ventilator-associated pneumonia showed that mortality and relapse rates were noninferior in patients who received 8 versus 15 days of treatment, but similar evidence is lacking for the treatment of patients with bloodstream infection, which affects 15% of critically ill patients. The Bacteremia Antibiotic Length Actually Needed for Clinical Effectiveness (BALANCE) research program was initiated to provide evidence-based guidance on this question.
鉴于耐药性迅速上升和新药开发减少,许多全球卫生组织已宣布抗菌素耐药性对健康构成威胁。据估计,高达30%-50%的抗生素使用是不适当的,治疗时间过长是不适当使用的最大因素。一项针对呼吸机相关肺炎危重患者的具有里程碑意义的试验表明,接受8天和15天治疗的患者死亡率和复发率并不低,但对于血液感染患者的治疗缺乏类似的证据,血液感染影响15%的危重患者。“菌血症抗生素临床疗效实际所需长度”(BALANCE)研究项目的启动就是为了在这个问题上提供循证指导。
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引用次数: 0
TAME cardiac arrest: A phase III multicenter randomized trial of targeted therapeutic mild hypercapnia after resuscitated cardiac arrest TAME心脏骤停:复苏心脏骤停后靶向治疗轻度高碳酸血症的III期多中心随机试验
Pub Date : 2017-11-01 DOI: 10.4103/SCCJ.SCCJ_23_17
G. Eastwood, A. Nichol, R. Bellomo, Y. Arabi
Cardiac arrest (CA) is a catastrophic world-wide health problem with substantial human and financial costs. Ongoing cerebral vasoconstriction and cerebral hypoxia during the early post-resuscitation period may contribute to the often poor neurological outcome in CA survivors. Arterial carbon dioxide (PaCO2) is the major determinant of cerebral blood flow and an increased PaCO2 (hypercapnia) markedly increases cerebral blood flow and oxygenation. This paper reports on the background and method of The TAME Cardiac Arrest trial (Clinicaltrials.gov (NCT03114033) which is a phase III multi-center, randomized, parallel-group, controlled trial. The trial will determine if targeted therapeutic mild hypercapnia (TTMH) (PaCO250-55mmHg) during mechanical ventilation improves neurological outcome at 6 months compared to targeted normocapnia (TN) (PaCO235-45 mmHg) in resuscitated CA patients. The intervention is cost-free and will be applied over the first 24-hours of ICU care. A total of 1700 adult resuscitated CA patients from ICUs around the world will be enrolled. When completed the TAME Cardiac Arrest trial will provide unprecedented insights that will transform the care of resuscitated CA patients admitted to the intensive care unit (ICU) around the world. Moreover, this therapy is cost free and, if shown to be effective, will improve thousands of lives, transform clinical practice, and yield major financial savings.
心脏骤停(CA)是一个全球性的灾难性健康问题,具有巨大的人力和财力成本。复苏后早期持续的脑血管收缩和脑缺氧可能导致CA幸存者的神经预后往往较差。动脉二氧化碳(PaCO2)是脑血流量的主要决定因素,PaCO2升高(高碳酸血症)显著增加脑血流量和氧合。本文报道TAME心脏骤停试验(Clinicaltrials.gov (NCT03114033))的背景和方法,这是一项多中心、随机、平行组、对照的III期试验。该试验将确定在复苏的CA患者中,与靶向正常碳酸血症(TN) (paco235 - 45mmhg)相比,机械通气期间靶向治疗性轻度高碳酸血症(TTMH) (PaCO250-55mmHg)是否能改善6个月时的神经系统预后。该干预措施是免费的,将在ICU护理的前24小时内应用。来自世界各地icu的1700名成人复苏CA患者将被纳入研究。TAME心脏骤停试验完成后,将提供前所未有的见解,将改变全球重症监护病房(ICU)收治的复苏CA患者的护理。此外,这种疗法是免费的,如果证明有效,将改善成千上万人的生活,改变临床实践,并节省大量资金。
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引用次数: 4
Prevalence and outcomes of colistin-resistant Acinetobacter infection in Saudi critical care units 沙特重症监护病房中耐粘菌素不动杆菌感染的患病率和结果
Pub Date : 2017-11-01 DOI: 10.4103/SCCJ.SCCJ_28_17
A. Kharaba
Acinetobacter baumannii is a common healthcare associated problem. It can cause a wide variety of nosocomial infections because of its tremendous ability of acquiring antibiotic resistance and to survive in hospital environments. It's associated with high morbidity and mortality. So it has been considered as one of the dangerous organisms by the Infectious Diseases Society of America. In Saudi Arabia, many studies highlighted the magnitude of Acinetobacter baumannii infections but most of the studies were small. We plan to conduct a large multicenter prospective study in major ICUs in Saudi Arabia to determine the prevalence and prognosis of Acinetobacter baumannii infection, resistant pattern, risk factors associated with resistant and outcomes.
鲍曼不动杆菌是一种常见的保健相关问题。它可以引起各种各样的医院感染,因为它具有获得抗生素耐药性和在医院环境中生存的巨大能力。它与高发病率和高死亡率有关。因此它被美国传染病学会认为是一种危险的有机体。在沙特阿拉伯,许多研究强调了鲍曼不动杆菌感染的严重程度,但大多数研究规模较小。我们计划在沙特阿拉伯的主要icu中开展一项大型多中心前瞻性研究,以确定鲍曼不动杆菌感染的患病率和预后、耐药模式、与耐药相关的危险因素和结局。
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引用次数: 2
期刊
Saudi Critical Care Journal
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