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Erratum: Antibiotic Treatment Duration for Bloodstream Infections in Critically Ill Patients: A National Survey of Kuwaiti Infectious Diseases and Critical Care Specialists 勘误:重症患者血流感染的抗生素治疗持续时间:科威特传染病和重症监护专家全国调查
Pub Date : 2024-01-12 DOI: 10.4103/2543-1854.393564
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引用次数: 0
Effects of different regimens of sedation on mechanically ventilated patients 不同镇静方案对机械通气患者的影响
Pub Date : 2023-04-01 DOI: 10.4103/sccj.sccj_31_22
Usama Badr, Hossam Fouad Rida, Amr A Elmorsy
Background: Up to one-third of intensive care unit (ICU) patients worldwide undergo mechanical ventilation. These patients frequently require analgesics and sedatives-potent medications with clear benefits and significant side effects. Objective: The current study intended to assess the effects of application of different regimens of sedation on mechanically ventilated patients regarding the length of ventilator days, length of hospital stay, multiple organ dysfunctions, ventilator-associated pneumonia (VAP), and mortality. Methods: One hundred adult patients who are intubated for any cause and attached to mechanical ventilation for more than 24 h will be included in this study. Drugs used for sedation were propofol and midazolam. Patients underwent history taking, clinical examination, laboratory investigations, chest X-ray, and electrocardiogram on admission. Results: At the end of this study, it was found that there was a significant increase in the sedation holiday group (Group II) over the no sedation group (Group I) regarding multiple organ dysfunction score, VAP, ventilator days, ICU stay, and hospital stay but there was no significant difference between both groups regarding mortality, spontaneous breathing trials, Glasgow Coma Scale, and complete blood count. Conclusions: Our results demonstrate that the use of sedatives can cause prolongation in the duration of mechanical ventilation, length of stay in the ICU, and total length of hospital stay. In addition, there is an increased risk of morbidity and mortality. It is possible to use a strategy of no sedation for critically ill patients undergoing mechanical ventilation without fears of failure.
背景:全世界多达三分之一的重症监护病房(ICU)患者接受机械通气。这些患者经常需要使用镇痛药和镇静剂,这些强效药物具有明显的疗效和明显的副作用。目的:本研究旨在评估不同镇静方案对机械通气患者使用呼吸机天数、住院时间、多器官功能障碍、呼吸机相关性肺炎(VAP)和死亡率的影响。方法:将100例因任何原因插管并机械通气超过24小时的成年患者纳入本研究。用于镇静的药物是异丙酚和咪达唑仑。患者入院时接受病史、临床检查、实验室检查、胸片及心电图检查。结果:在本研究结束时,我们发现镇静假期组(II组)在多器官功能障碍评分、VAP、呼吸机天数、ICU住院时间和住院时间方面明显高于未镇静组(I组),但两组在死亡率、自主呼吸试验、格拉斯哥昏迷评分和全血细胞计数方面无显著差异。结论:我们的研究结果表明,使用镇静剂会导致机械通气时间延长,ICU住院时间延长,总住院时间延长。此外,发病率和死亡率的风险也在增加。对危重病人进行机械通气时,可以使用不镇静的策略,而不必担心失败。
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引用次数: 0
Predictors of clinical deterioration of hospitalized adult medical patients: An integrative literature review protocol 成人住院患者临床恶化的预测因素:综合文献回顾方案
Pub Date : 2023-04-01 DOI: 10.4103/sccj.sccj_30_22
A. Deeb, Joy Maddigan
Clinical deterioration of hospitalized medical patients negatively affects patient outcomes and hospital capacity. Failure to recognize and respond promptly to an individual's worsening health status can lead to complications with far-reaching impacts on the patient and family. The ability to identify patient cues that can predict clinical deterioration is an essential role for frontline health-care providers to avert an avoidable health crisis. This protocol is designed to describe an integrative literature review plan that aims to identify, analyze, and synthesize the predictors and associated factors underlying the clinical deterioration of hospitalized medical ward patients. This planned review will follow the methodology of Whittemore and Knafl (2005), which comprises five stages: problem identification, literature search, data evaluation, data analysis, and presentation. CINAHL Plus, Embase, and PubMed databases will be used in the literature search. Primary research studies focusing on the predictors or the associated factors of clinical deterioration among medical ward patients will be eligible for the review. The quality of selected articles will be critically appraised using the Joanna Briggs Institute tools. The process of findings synthesis will be conducted according to Miles and Huberman (1994), which consists of data reduction, data display, data comparison, conclusion drawing, and verification. The findings will be presented as major themes that are supported by the appropriate primary studies.
住院医疗患者的临床恶化对患者预后和医院能力产生负面影响。未能及时认识和应对个人恶化的健康状况可能导致并发症,对患者和家庭产生深远的影响。识别可预测临床恶化的患者线索的能力对于一线卫生保健提供者避免可避免的健康危机至关重要。本方案旨在描述一个综合文献综述计划,旨在识别、分析和综合住院病房患者临床恶化的预测因素和相关因素。这个计划的审查将遵循Whittemore和Knafl(2005)的方法,包括五个阶段:问题识别,文献检索,数据评估,数据分析和展示。文献检索将使用CINAHL Plus、Embase和PubMed数据库。重点关注内科病房患者临床恶化的预测因素或相关因素的初步研究将有资格纳入本综述。所选文章的质量将使用乔安娜布里格斯研究所的工具进行严格的评估。研究结果综合的过程将根据Miles和Huberman(1994)进行,包括数据缩减、数据显示、数据比较、得出结论和验证。研究结果将作为主要主题提出,并得到适当的初步研究的支持。
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引用次数: 0
Characteristics and outcomes of adolescents requiring admission to the intensive care unit: A retrospective cohort study 需要进入重症监护病房的青少年的特征和结果:一项回顾性队列研究
Pub Date : 2023-04-01 DOI: 10.4103/sccj.sccj_9_23
H. Al-Dorzi, Amirah Yaqoub, Fisal T Aldokhel, Khalid Alshuwaier, Sarah F Almujarri, Fatimah A Alkhaldi
Background: Critically ill adolescents are not a well-studied patient population. The optimal setting (pediatric or adult intensive care unit [ICU]) for caring for them is not clear. This study assessed adolescents admitted to the adult ICU and compared the characteristics and outcomes of younger versus older patients. Methods: This was a retrospective study of adolescent patients aged 14–19 years who were admitted to an adult tertiary care ICU between January 1, 2015, and December 31, 2020. Patients were divided into two groups, younger (14–16 years old) and older adolescents (17–19 years old). Results: The study included 276 patients; 105 patients were aged 14–16 years and 171 patients 17–19 years. Most patients were males (69.9%); only nine patients had body weights < 30 kg. Trauma was the most common reason for admission (36.2% of the younger group and 49.7% of the older group, P = 0.03) with sepsis being also common (19% of the younger group and 20.5% of the older group). Vasopressor therapy was required for 39.1% of patients and invasive mechanical ventilation for 58% (no between-group difference). The hospital mortality was 16.7% (odds ratio in younger versus older group adjusted for illness severity, 0.804; 95% confidence interval, 0.358–1.802). Mechanical ventilation duration and stay in the ICU and hospital were similar in both groups. Conclusions: Trauma was the most common reason for admission of adolescents aged 14–19 years to the adult ICU. The hospital mortality of younger and older adolescents was similar, suggesting that the management of younger adolescents in the adult ICU is safe.
背景:危重青少年并不是一个被充分研究的患者群体。照顾他们的最佳环境(儿科或成人重症监护病房[ICU])尚不清楚。本研究评估了入住成人ICU的青少年,并比较了年轻患者和老年患者的特征和结果。方法:对2015年1月1日至2020年12月31日期间入住成人三级护理ICU的14-19岁青少年患者进行回顾性研究。患者分为两组,年龄较小的(14-16岁)和较大的青少年(17-19岁)。结果:共纳入276例患者;年龄14-16岁105例,17-19岁171例。患者以男性居多(69.9%);只有9例患者体重< 30kg。创伤是最常见的入院原因(36.2%的年轻组和49.7%的老年组,P = 0.03),败血症也很常见(19%的年轻组和20.5%的老年组)。39.1%的患者需要血管加压治疗,58%的患者需要有创机械通气(组间无差异)。住院死亡率为16.7%(经疾病严重程度调整后,年轻组与老年组的优势比为0.804;95%置信区间,0.358-1.802)。两组患者机械通气时间、ICU住院时间和住院时间相似。结论:创伤是14-19岁青少年进入成人ICU的最常见原因。青少年和大龄青少年的住院死亡率相似,提示在成人ICU对青少年的管理是安全的。
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引用次数: 0
Antibiotic treatment duration for bloodstream infections in critically ill patients: A national survey of Kuwaiti infectious diseases and critical care specialists 危重病人血液感染的抗生素治疗持续时间:科威特传染病和危重护理专家的全国调查
Pub Date : 2023-04-01 DOI: 10.4103/sccj.sccj_10_23
Buskandar Fahad, Alalayet Abdulrahman, D. Nick, Fowler Robert
Context: Antibiotic treatment duration for bloodstream infections (BSIs) is an area of controversy and uncertainty. Aims: Our objective was to assess antibiotic treatment duration practices for critically ill patients with BSIs in Kuwait. Subjects and Methods: A survey consisting of clinical scenarios followed by questions about recommended antibiotic treatment duration for each scenario was sent to Kuwaiti infectious diseases, critical care specialists, and anesthetists with critical care experience. Statistical Analysis Used: Descriptive analysis (medians and interquartile ranges) and Kruskal–Wallis test were used for statistical analysis. Results: The survey response rate was 68% (112/164). The median (interquartile range [IQR]) ranges for antibiotic duration recommendations were similar for each bacteremic syndrome: central line-associated BSIs, 10 days (7–14); pneumonia, 10 days (7–14); urinary tract infection, 10 days (7–14); intra-abdominal infection, 10 days (7–14); and skin and soft-tissue infection, 10 days (7–14). The median (IQR) antibiotic durations for the following bacteria were as follows: Staphylococcus aureus, 14 days (10–14); extended-spectrum beta-lactamase Escherichia coli, 10 days (7–14); multidrug-resistant (MDR) Pseudomonas aeruginosa, 14 days (10–14); MDR Acinetobacter baumannii, 14 days (10–14); vancomycin-resistant Enterococcus faecalis, 14 days (10–14); carbapenem-resistant Klebsiella pneumoniae, 14 days (10–14); and coagulase-negative Staphylococcus, 7 days (7–10). For all infectious syndromes and individual organisms, duration responses often followed discrete choices of 5, 7, 10, and 14 days. Prolonging antibiotic therapy for immunocompromised patients was favored among 70% of respondents. Conclusions: This survey demonstrates practice variation in treating BSIs and supports the need for adequately powered randomized controlled trials assessing optimal antibiotic duration for various bacteremic syndromes, pathogens, and resistance patterns.
背景:血流感染(bsi)的抗生素治疗持续时间是一个有争议和不确定的领域。目的:我们的目的是评估科威特患有bsi的危重患者的抗生素治疗持续时间。研究对象和方法:一份由临床场景组成的调查,然后是关于每种场景推荐的抗生素治疗时间的问题,该调查被发送给科威特传染病、重症监护专家和具有重症监护经验的麻醉师。统计学分析方法:采用描述性分析(中位数和四分位间距)和Kruskal-Wallis检验进行统计学分析。结果:调查回复率为68%(112/164)。推荐抗生素使用时间的中位数(四分位间距[IQR])范围对于每种菌血症综合征是相似的:中心线相关性bsi, 10天(7-14天);肺炎,10天(7-14天);尿路感染,10天(7-14);腹腔感染,10天(7-14);皮肤及软组织感染,10天(7 ~ 14天)。以下细菌的抗生素使用时间中位数(IQR)如下:金黄色葡萄球菌,14天(10-14天);广谱β -内酰胺酶大肠杆菌,10天(7-14);耐多药铜绿假单胞菌,14天(10-14);耐多药鲍曼不动杆菌,14天(10-14);耐万古霉素粪肠球菌,14天(10-14);耐碳青霉烯肺炎克雷伯菌,14天(10-14);凝固酶阴性葡萄球菌,7天(7 - 10)。对于所有感染综合征和个体生物体,持续时间反应通常是5、7、10和14天的离散选择。70%的应答者赞成延长免疫功能低下患者的抗生素治疗。结论:该调查显示了治疗bsi的实践差异,并支持有必要进行足够有力的随机对照试验,评估各种菌血症综合征、病原体和耐药模式的最佳抗生素持续时间。
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引用次数: 0
Use of critical care ultrasound in Saudi Arabia: Questionnaire analysis 沙特阿拉伯重症监护超声的使用:问卷分析
Pub Date : 2023-04-01 DOI: 10.4103/sccj.sccj_7_23
Eslam E. Abdelshafey, Nashwa Abdalkreem, Ashraf S. Altayar
Basic skills and knowledge of critical care ultrasonography (CCUS) are considered mandatory in intensive care unit (ICU) practice. A link for the survey questionnaire [Appendix 1] was distributed to attendees of critical care meetings from different regions in Saudi Arabia about the topics of CCUS availability, use for diagnosis, and intervention. Responses were recorded for 48 h from launching on 1st day. We received 172 full responses, 95% of responders claimed that they have their own ultrasound machines in their units. In the opinion of 85.5% of the responders, the need for CCUS in ICU is mandatory and 14% of responders see it as optional. A significant positive association was found between responders' years of experience and obstacles to use CCUS (P < 0.001), while there was no significant association regarding responders' specialties, work region in Saudi Arabia and type of hospital they are working in (P = 0.509, 0.081, and 0.122, respectively).
重症监护超声检查(CCUS)的基本技能和知识在重症监护病房(ICU)的实践中被认为是强制性的。调查问卷的链接[附录1]被分发给来自沙特阿拉伯不同地区的重症监护会议的与会者,主题是CCUS的可用性、用于诊断和干预。从第1天发射开始记录48小时内的反应。我们收到了172份完整的回复,95%的回复者声称他们的单位里有自己的超声波仪。85.5%的应答者认为ICU需要CCUS是强制性的,14%的应答者认为CCUS是可选的。应答者的经验年限与CCUS使用障碍之间存在显著正相关(P < 0.001),而应答者的专业、沙特阿拉伯的工作区域和他们工作的医院类型之间没有显著关联(P分别= 0.509、0.081和0.122)。
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引用次数: 0
The presence of moral distress among critical care nurses in Saudi Arabia 沙特阿拉伯重症护理护士中存在的道德困境
Pub Date : 2023-01-01 DOI: 10.4103/sccj.sccj_29_22
Jennifer de Beer, Dalia Sunari, Seema Nasser, Zahra Alnasser, H. Rawas, H. Alnajjar
Background: Moral distress (MD) was first defined as a situation in which one knows the right thing to do, but institutional constraints make it nearly impossible to pursue the right course of action. This can be even more challenging within the critical care context as critical the care context imposes physical, emotional, and cognitive stressors on critical care nurses. Methodology: A descriptive quantitative approach was followed, and the critical care units of two tertiary hospitals in two provinces in Saudi Arabia were included in the study, yielding a cluster sample size of 361 critical care nurses. Data were collected using the MD Scale-Revised, for which reliability and validity have been established. Results: The mean total MD experienced by respondents was 77.15 ± 58.32, representing a low level of MD. The statement that nurses indicated as causing the most distress was “follow the family's wishes to continue life support even though I believe it is not in the best interest of the patient” with 5.98 ± 5.04. Furthermore, 17.5% (n = 63) of nurses had considered leaving their positions because of MD. MD was the highest in the Emergency department with 102.12 ± 70.59; as experience increased by 1 year, the MD score increased by 11.56. Conclusion: When dealing with issues related to futile care, critical care nurses experience MD. Therefore, future research is required to develop appropriate interventions with which to address critical care-related MD.
背景:道德困境(MD)最初被定义为一种情况,在这种情况下,一个人知道该做什么是正确的,但制度上的限制使其几乎不可能采取正确的行动。在重症监护环境中,这可能更具挑战性,因为重症监护环境对重症监护护士施加了身体,情感和认知压力。方法:采用描述性定量方法,并将沙特阿拉伯两个省的两家三级医院的重症监护病房纳入研究,产生361名重症监护护士的整群样本。数据采用修订的MD量表收集,并建立了信度和效度。结果:受访者经历的MD平均为77.15±58.32,代表了低水平的MD。护士认为造成最大痛苦的陈述是“尽管我认为这不是患者的最佳利益,但仍遵循家人的意愿继续维持生命支持”,得分为5.98±5.04。17.5% (n = 63)的护士曾因MD考虑离职,其中急诊科的MD最高,为102.12±70.59;经验每增加1年,MD得分增加11.56分。结论:在处理与无效护理相关的问题时,重症护理护士会经历MD。因此,未来的研究需要开发适当的干预措施来解决重症护理相关的MD。
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引用次数: 0
Sedation and analgesia practices of pediatric intensivists in Saudi Arabia 镇静和镇痛的做法儿科重症医师在沙特阿拉伯
Pub Date : 2023-01-01 DOI: 10.4103/sccj.sccj_25_22
M. Bakhsh, Mohamed M. Humoodi, Abdullah A. Alzahrani, S. Osman, R. Babakr, Nada Townsi, Maha Azzam
Background: Sedation practices in pediatric intensive care units (PICUs) vary significantly worldwide. This study aimed to explore the current sedation and analgesia practices among paediatric intensivists in Saudi Arabia. Methods: This web-based survey was conducted among pediatric intensive care physicians in Saudi Arabia. The survey investigated the participating PICUs, physicians' demographic data, and sedation/analgesia practices. Results: Of the 160 physicians included, the response rate was 67% (n = 108). Of the 100 participants who provided location information, 51% (n = 51) were from the central region of Saudi Arabia. Approximately two-thirds of the participants were consultants, and 48.1% had >10 years of experience. Most respondents practised in general PICUs and routinely assessed sedation and analgesia levels. The COMFORT-Behavior and Face, Legs, Activity, Cry, and Consolability scales were popular (42.6%). More than half of the respondents (52/98) did not practice daily sedation interruption. Furthermore, 78.3% of the respondents assessed patients for withdrawal, whereas only 25% used delirium screening scores. Infusions were preferred over interrupted doses to provide comfort for mechanically ventilated patients. The first-choice infusions were midazolam for sedation and fentanyl for analgesia. Dexmedetomidine was preferred when a third agent was required. Sedation protocols were used by 41.2% of the respondents and were mainly physician-led (75.2%). Various nonpharmacological measures were used to provide patient comfort, and parents often participated in their application. Conclusions: The practice of sedation varies significantly between pediatric intensivists, and formal assessment for delirium is infrequently done in PICUs in Saudi Arabia.
背景:世界各地儿童重症监护病房(picu)的镇静实践差异很大。本研究旨在探讨当前镇静和镇痛的做法中儿科重症医师在沙特阿拉伯。方法:这项基于网络的调查在沙特阿拉伯的儿科重症监护医生中进行。该调查调查了参与的picu、医生的人口统计数据和镇静/镇痛做法。结果:纳入的160名医生中,有效率为67% (n = 108)。在提供位置信息的100名参与者中,51% (n = 51)来自沙特阿拉伯中部地区。大约三分之二的参与者是顾问,48.1%的人有>10年的经验。大多数应答者在一般picu中进行实践,并常规评估镇静和镇痛水平。舒适行为和面部、腿部、活动、哭泣和安慰量表受欢迎(42.6%)。超过一半的受访者(52/98)没有每天进行镇静中断。此外,78.3%的受访者评估了患者的戒断行为,而只有25%的受访者使用了谵妄筛查评分。输液优于中断剂量,为机械通气患者提供舒适。首选输液为镇静用咪达唑仑,镇痛用芬太尼。当需要第三种药物时,首选右美托咪定。41.2%的受访者使用镇静方案,主要由医生主导(75.2%)。使用各种非药物措施来提供患者舒适,家长经常参与他们的应用。结论:不同儿科重症医师使用镇静的做法差异很大,在沙特阿拉伯的picu中很少对谵妄进行正式评估。
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引用次数: 0
A rare complication of intra-aortic balloon pump 主动脉内球囊泵的罕见并发症
Pub Date : 2023-01-01 DOI: 10.4103/sccj.sccj_28_22
Mohamed Aboughanima, Abdelhameed Elsayed, Amr A. Arafat
Intra-aortic balloon pump (IABP) is commonly used for circulatory support in patients with cardiogenic shock. IABP is associated with several complications; however, IABP rupture was rarely reported. We present a female patient with acute myocardial infarction and ventricular septal rupture. The patient underwent transcatheter device closure of the ventricular septum and IABP insertion. After 4 days of insertion, we encountered a failure to cycle alarm. The IABP was removed with difficulty, and a leak coming from the shaft near the bifurcation was found. This case highlighted the importance of early detection of IABP rupture to avoid entrapment and further complications.
主动脉内球囊泵(IABP)常用于心源性休克患者的循环支持。IABP与几种并发症有关;然而,IABP破裂很少被报道。我们报告一位女性急性心肌梗死并发室间隔破裂。患者接受了经导管装置关闭室间隔和IABP插入。插入4天后,我们遇到了循环报警失败。IABP被艰难地移除,并从分叉附近的竖井泄漏。这个病例强调了早期发现IABP破裂的重要性,以避免夹陷和进一步的并发症。
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引用次数: 0
ECPella: High-risk percutaneous coronary intervention in cardiogenic shock “case report” ECPella:高危经皮冠状动脉介入治疗心源性休克病例报告
Pub Date : 2022-07-01 DOI: 10.4103/sccj.sccj_18_22
R. Qutob, Alanoud A. Alkhannani, A. Hussain, O. Shammeri, A. Elhazmi
The utilization of mechanical circulatory support devices in high-risk percutaneous coronary interventions (PCI) has recently evolved. In Saudi Arabia, the use of such devices is under-reported. Here, we present a 36-year-old patient who was admitted to the hospital with a non-ST-elevation myocardial infarction with biventricular dysfunction. A high-risk PCI consist of unprotected left main stenting was performed with the assistance of venoarterial extracorporeal membrane oxygenation that allowed smooth and successful intervention. Two days later, Impella was used to augment the recovery of the myocardium. The implementation of this approach helped our patient hemodynamically and allowed the recovery of the myocardium.
机械循环支持装置在高风险经皮冠状动脉介入治疗(PCI)中的应用近年来不断发展。在沙特阿拉伯,这类装置的使用很少被报道。在这里,我们提出一个36岁的病人谁是入院的非st段抬高心肌梗死双心室功能障碍。高风险PCI包括无保护的左主干支架术,在静脉动脉体外膜氧合的帮助下进行,允许顺利和成功的干预。2天后,使用Impella来促进心肌的恢复。这种方法的实施有助于患者的血流动力学,并允许心肌的恢复。
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引用次数: 0
期刊
Saudi Critical Care Journal
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