Introducción: el Reconocimiento Emocional Auditivo (REA) es la capacidad de reconocer estados emocionales en otros, poniendo énfasis en las características prosódicas, tales como tono, intensidad y frecuencia. La literatura sobre esta área es escasa y en la actualidad no hay baterías de estímulos de REA validadas en Latinoamérica. Objetivo: evaluar una batería de estímulos de REA en una muestra de la población adulta chilena. Material y métodos: 140 adultos de entre 18 y 50 años de edad respondieron un formulario online que cual contuvo la batería de estímulos auditivos y preguntas asociadas. Los estímulos fueron elaborados a través de un modulador sintético de acuerdo a los parámetros sugeridos en la literatura. Se solicitó a los participantes que asociaran los estímulos auditivos a estados emocionales. Resultados: la característica F0M es clave para el reconocimiento de las emociones alegría y enojo, F0SD es importante para la emoción Tristeza y HF500 para la emoción enojo, y se encontraron diferencias significativas entre las medias de respuesta entre participantes que reportaron un trastorno psiquiátrico al momento del estudio y participantes que no. Conclusiones: varios de los estímulos testeados fueron evaluados por los participantes como representativos de algún estado emocional en alta proporción. Se recomienda realizar estudios posteriores de validación evaluando el grado de acuerdo y la realización de análisis factorial.
{"title":"Evaluación de una Batería de Estímulos de Reconocimiento Emocional Auditivo","authors":"Johanna Kreither, Renata Contreras, José Cueto","doi":"10.31157/an.v28i2.436","DOIUrl":"https://doi.org/10.31157/an.v28i2.436","url":null,"abstract":"\u0000Introducción: el Reconocimiento Emocional Auditivo (REA) es la capacidad de reconocer estados emocionales en otros, poniendo énfasis en las características prosódicas, tales como tono, intensidad y frecuencia. La literatura sobre esta área es escasa y en la actualidad no hay baterías de estímulos de REA validadas en Latinoamérica. \u0000 \u0000 \u0000Objetivo: evaluar una batería de estímulos de REA en una muestra de la población adulta chilena. \u0000 \u0000 \u0000Material y métodos: 140 adultos de entre 18 y 50 años de edad respondieron un formulario online que cual contuvo la batería de estímulos auditivos y preguntas asociadas. Los estímulos fueron elaborados a través de un modulador sintético de acuerdo a los parámetros sugeridos en la literatura. Se solicitó a los participantes que asociaran los estímulos auditivos a estados emocionales. \u0000 \u0000 \u0000Resultados: la característica F0M es clave para el reconocimiento de las emociones alegría y enojo, F0SD es importante para la emoción Tristeza y HF500 para la emoción enojo, y se encontraron diferencias significativas entre las medias de respuesta entre participantes que reportaron un trastorno psiquiátrico al momento del estudio y participantes que no. \u0000 \u0000 \u0000Conclusiones: varios de los estímulos testeados fueron evaluados por los participantes como representativos de algún estado emocional en alta proporción. Se recomienda realizar estudios posteriores de validación evaluando el grado de acuerdo y la realización de análisis factorial. \u0000 \u0000 \u0000 \u0000","PeriodicalId":34902,"journal":{"name":"Archivos de Neurociencias","volume":"76 5 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83464347","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Javier Degollado-García, Ricardo Marian-Magaña, A. Hernández-Hernández, Eliezer Villanueva-Castro, Daniel Ballesteros-Herrera, J. Gómez-Amador
It is important to understand the patient's vascular anatomy before treating cerebral aneurysms. The middle artery of the corpus callosum is one of the least common variations of the AComA complex. We describe the case of a 59-year-old woman who suffered a subarachnoid hemorrhage due to an AComA complex aneurysm that had ruptured. Fluorescein injection during the aneurysm clipping procedure revealed a partial obstruction of the middle artery, requiring repositioning of the clip. The vascular variations that our patients may exhibit at the time of aneurysm clipping must be kept in mind and understood.
{"title":"Median artery of the corpus callosum in the context of AComA aneurysm rupture: The relevance of a perianeurysmal anatomy","authors":"Javier Degollado-García, Ricardo Marian-Magaña, A. Hernández-Hernández, Eliezer Villanueva-Castro, Daniel Ballesteros-Herrera, J. Gómez-Amador","doi":"10.31157/an.v28i2.421","DOIUrl":"https://doi.org/10.31157/an.v28i2.421","url":null,"abstract":"It is important to understand the patient's vascular anatomy before treating cerebral aneurysms. The middle artery of the corpus callosum is one of the least common variations of the AComA complex. We describe the case of a 59-year-old woman who suffered a subarachnoid hemorrhage due to an AComA complex aneurysm that had ruptured. Fluorescein injection during the aneurysm clipping procedure revealed a partial obstruction of the middle artery, requiring repositioning of the clip. The vascular variations that our patients may exhibit at the time of aneurysm clipping must be kept in mind and understood.","PeriodicalId":34902,"journal":{"name":"Archivos de Neurociencias","volume":"25 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82169932","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Appreciation to Reviewers 2022","authors":"Editorial Council","doi":"10.31157/an.v28i2.453","DOIUrl":"https://doi.org/10.31157/an.v28i2.453","url":null,"abstract":"","PeriodicalId":34902,"journal":{"name":"Archivos de Neurociencias","volume":"16 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78698745","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Edwin Steven Vargas Cañas, Miriam Marcela Hernandez Sanchez, Javier Andres Galnares Olalde, Adib Jorge de Saráchaga, Ana Lissette Bazán Rodríguez, Raul Nathanael May Mas, J. C. López-Hernández
Background: Guillain-Barré syndrome (GBS) is the most common cause of acute flaccid paralysis worldwide. Lymphocytes and neutrophils are associated with systemic inflammation and production of proinflammatory mediators. GBS, as an autoimmune disease, elicits an upregulation in inflammatory and metabolic pathways, with increased production of lymphocytes and neutrophils. Serum markers such as the neutrophil-lymphocyte (NLR) and leuko-glycemic (LGR) ratios have been studied for the severity and prognosis of non-neurological disorders. Methods: A cross-sectional study from a prospective cohort of patients with GBS was conducted, from January 2018 to February 2021. Comparison between patients with or without ventilatory support was performed with student´s t test or Mann-Whitney U test based on distribution. Chi-square for was used for categorical variables, Fisher´s exact test was applied when necessary. A logistic regression analysis was performed. Results: One hundred and twenty-three patients were included. Logistic regression analysis demonstrated NLI to be an independent factor for mechanical ventilation in GBS, but not for LGI and OR 2.0, respectively. Both LGI and NLI demonstrated a high performance for ventilatory support prediction, with 0.70 and 0.81, respectively. Best cut-off values, according to Youden index, are for LGI 1.12 (sensitivity 0.70, specificity 0.40) and for NLI 3.59 (sensitivity 0.78, specificity 0.33). Conclusions: Despite the wide use of the EGRIS scale in estimating respiratory insufficiency in patients with GBS, we portray a new and easy to obtain laboratory tool that can further help non-neurologists and other clinicians to predict the risk for ventilatory support.
{"title":"Neutrophil-lymphocyte and leuko-glycemic indices as predictive markers for ventilatory support in patients with Guillain-Barre syndrome","authors":"Edwin Steven Vargas Cañas, Miriam Marcela Hernandez Sanchez, Javier Andres Galnares Olalde, Adib Jorge de Saráchaga, Ana Lissette Bazán Rodríguez, Raul Nathanael May Mas, J. C. López-Hernández","doi":"10.31157/an.v28i2.413","DOIUrl":"https://doi.org/10.31157/an.v28i2.413","url":null,"abstract":"Background: Guillain-Barré syndrome (GBS) is the most common cause of acute flaccid paralysis worldwide. Lymphocytes and neutrophils are associated with systemic inflammation and production of proinflammatory mediators. GBS, as an autoimmune disease, elicits an upregulation in inflammatory and metabolic pathways, with increased production of lymphocytes and neutrophils. Serum markers such as the neutrophil-lymphocyte (NLR) and leuko-glycemic (LGR) ratios have been studied for the severity and prognosis of non-neurological disorders. \u0000Methods: A cross-sectional study from a prospective cohort of patients with GBS was conducted, from January 2018 to February 2021. Comparison between patients with or without ventilatory support was performed with student´s t test or Mann-Whitney U test based on distribution. Chi-square for was used for categorical variables, Fisher´s exact test was applied when necessary. A logistic regression analysis was performed. \u0000Results: One hundred and twenty-three patients were included. Logistic regression analysis demonstrated NLI to be an independent factor for mechanical ventilation in GBS, but not for LGI and OR 2.0, respectively. Both LGI and NLI demonstrated a high performance for ventilatory support prediction, with 0.70 and 0.81, respectively. Best cut-off values, according to Youden index, are for LGI 1.12 (sensitivity 0.70, specificity 0.40) and for NLI 3.59 (sensitivity 0.78, specificity 0.33). \u0000Conclusions: Despite the wide use of the EGRIS scale in estimating respiratory insufficiency in patients with GBS, we portray a new and easy to obtain laboratory tool that can further help non-neurologists and other clinicians to predict the risk for ventilatory support.","PeriodicalId":34902,"journal":{"name":"Archivos de Neurociencias","volume":"58 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76959211","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
El signo de Romberg es uno de los signos clásicos y de gran ayuda en la exploración neurológica. Fue descrito por el alemán Mortiz Heinrich Romberg en 1851, al describir la pérdida del control postural que experimentaban los pacientes con tabes dorsal después de cerrar los ojos o en la oscuridad. En la literatura se reporta diferentes descripciones del signo de Romberg, y actualmente no existe un consenso de la descripción de este signo. El signo de Romberg fue relacionado con el daño a la vía propioceptiva en sus primeras descripciones, y no solo se utiliza en la neurología, también es utilizado en otras áreas médicas. Por lo que el signo de Romberg continúa siendo de gran ayuda en la práctica médica.
隆伯格体征是一种经典的体征，对神经系统检查有很大的帮助。1851年，德国人莫蒂兹·海因里希·隆伯格(Mortiz Heinrich Romberg)描述了背板患者在闭上眼睛或在黑暗中失去姿势控制的情况。文献中对隆伯格符号有不同的描述，目前对该符号的描述没有共识。在他早期的描述中，Romberg的体征与本体感觉通路的损伤有关，它不仅用于神经学，也用于其他医学领域。因此，隆伯格的标志在医疗实践中仍然有很大的帮助。
{"title":"Signo de Romberg: Concepción histórica","authors":"J. López-Hernández, Arturo Violante Villanueva","doi":"10.31157/an.v28i2.443","DOIUrl":"https://doi.org/10.31157/an.v28i2.443","url":null,"abstract":"El signo de Romberg es uno de los signos clásicos y de gran ayuda en la exploración neurológica. Fue descrito por el alemán Mortiz Heinrich Romberg en 1851, al describir la pérdida del control postural que experimentaban los pacientes con tabes dorsal después de cerrar los ojos o en la oscuridad. \u0000En la literatura se reporta diferentes descripciones del signo de Romberg, y actualmente no existe un consenso de la descripción de este signo. El signo de Romberg fue relacionado con el daño a la vía propioceptiva en sus primeras descripciones, y no solo se utiliza en la neurología, también es utilizado en otras áreas médicas. Por lo que el signo de Romberg continúa siendo de gran ayuda en la práctica médica.","PeriodicalId":34902,"journal":{"name":"Archivos de Neurociencias","volume":"44 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85897889","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Annual Research Meeting 2022 from the National Institute of Neurology and Neurosurgery Manuel Velasco Suárez
国家神经病学和神经外科研究所Manuel Velasco举办的2022年年度研究会议Suárez
{"title":"XXXVI Annual Research Meeting 2022 from the National Institute of Neurology and Neurosurgery Manuel Velasco Suárez","authors":"Archivos de Neurociencias","doi":"10.31157/an.v27is2.447","DOIUrl":"https://doi.org/10.31157/an.v27is2.447","url":null,"abstract":"Annual Research Meeting 2022 from the National Institute of Neurology and Neurosurgery Manuel Velasco Suárez","PeriodicalId":34902,"journal":{"name":"Archivos de Neurociencias","volume":"490 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88730285","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ariel Camilo Marrugo-Ortiz, Cristina Isabela Ealo-Cardona, J. Diaz-Vallejo, Wendy Dayanna Cuji-Galarza, I. Lozada‐Martínez
1. School of Medicine, University of Cartagena, Cartagena, Colombia 2. School of Health Sciences, University of Caldas, Manizales, Colombia 3. School of Medical Science, University of Cuenca, Cuenca, Ecuador 4. Colombian Clinical Research Group in Neurocritical Care, Latin American Council of Neurocritical Care, Cartagena, Colombia 5. Prometheus and Biomedicine Applied to Clinical Sciences Research Group, School of Medicine, University of Cartagena, Cartagena, Colombia
{"title":"Brief bibliometric analysis of the participation of Latin American authors in TOP neurology journals during 2021: how big is the gap?","authors":"Ariel Camilo Marrugo-Ortiz, Cristina Isabela Ealo-Cardona, J. Diaz-Vallejo, Wendy Dayanna Cuji-Galarza, I. Lozada‐Martínez","doi":"10.31157/an.v28i2.442","DOIUrl":"https://doi.org/10.31157/an.v28i2.442","url":null,"abstract":"1. School of Medicine, University of Cartagena, Cartagena, Colombia 2. School of Health Sciences, University of Caldas, Manizales, Colombia 3. School of Medical Science, University of Cuenca, Cuenca, Ecuador 4. Colombian Clinical Research Group in Neurocritical Care, Latin American Council of Neurocritical Care, Cartagena, Colombia 5. Prometheus and Biomedicine Applied to Clinical Sciences Research Group, School of Medicine, University of Cartagena, Cartagena, Colombia","PeriodicalId":34902,"journal":{"name":"Archivos de Neurociencias","volume":"31 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79538946","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Tras haber leído el manuscrito escrito por nuestro par Parra-Medina1, en su manuscrito titulado "Mente y cerebro: de los egipcios a Cajal y los neuromitos", hemos decidido realizar algunos comentarios como aporte agregado. Para comenzar, coincidimos con el autor en relación con la amplia necesidad que cubrió la psicología cognitiva tras su genesis, así como el avance que originaron las aportaciones de Santiago Ramón y Cajal (1852-1934); empero, consideramos pertinente la mención de algunos hechos de actualidad que pudiesen ayudar al entendimiento de la interacción social, la conciencia y la mente. Si bien, no existe una localización primaria bien definida para la conciencia y / o la mente humana, hoy en día, la comprensión sobre la “cognición social” mediante las preguntas: ¿qué son los estados mentales?, ¿cómo son representados?, y ¿cómo nuestro cerebro nos permite entender otras mentes? se ha convertido en un tema importante para la investigación médica y psicosocial; tal hecho podría explicar el deterioro en las funciones ejecutivas y socio-emocionales (ej. dificultad del lenguaje verbal y no verbal) asociadas a ciertas condiciones neurológicas y psiquiátricas, tales como: el autismo, la esquizofrenia, la enfermedad de Alzheimer, la enfermedad de Parkinson e, incluso, la depresión. Como consecuencia ha nacido el constructo denominado “Teoría de la mente” (ToM por sus siglas en inglés), que busca explicar la capacidad mental innata para atribuir estados cognitivos a las situaciones cotidianas tanto para uno mismo (meta-cognición & meta-representación), como para otros sujetos; es decir, representa un mecanismo teórico creado para explicar la racionalidad humana dentro de un entorno social.
在阅读了我们的Parra-Medina1夫妇的手稿“mind and brain: from egypt to Cajal and the neuromythos”后，我们决定做一些评论作为补充贡献。首先，我们同意作者关于认知心理学起源后的广泛需求，以及圣地亚哥ramon y Cajal(1852-1934)的贡献所带来的进步;然而，我们认为有必要提到一些当前的事实，可能有助于理解社会互动，意识和思想。虽然人类意识和/或心灵没有一个明确定义的主要位置，但今天通过以下问题来理解“社会认知”:什么是精神状态?，它们是如何表现的?我们的大脑是如何让我们理解其他大脑的?已成为医学和社会心理研究的重要课题;这一事实可以解释与某些神经和精神疾病(如自闭症、精神分裂症、阿尔茨海默病、帕金森病，甚至抑郁症)相关的执行和社会情感功能(如语言和非语言语言困难)的恶化。因此，一种被称为“心智理论”(ToM)的建构应运而生，它试图解释一种天生的心智能力，即为自己(元认知和元表征)和其他主体将认知状态归因于日常情况;也就是说，它代表了一种在社会环境中解释人类理性的理论机制。
{"title":"El constructo de la teoría de la mente","authors":"Julio César López-Valdés, F. Jiménez-Ponce","doi":"10.31157/an.v28i1.417","DOIUrl":"https://doi.org/10.31157/an.v28i1.417","url":null,"abstract":"Tras haber leído el manuscrito escrito por nuestro par Parra-Medina1, en su manuscrito titulado \"Mente y cerebro: de los egipcios a Cajal y los neuromitos\", hemos decidido realizar algunos comentarios como aporte agregado. Para comenzar, coincidimos con el autor en relación con la amplia necesidad que cubrió la psicología cognitiva tras su genesis, así como el avance que originaron las aportaciones de Santiago Ramón y Cajal (1852-1934); empero, consideramos pertinente la mención de algunos hechos de actualidad que pudiesen ayudar al entendimiento de la interacción social, la conciencia y la mente. \u0000Si bien, no existe una localización primaria bien definida para la conciencia y / o la mente humana, hoy en día, la comprensión sobre la “cognición social” mediante las preguntas: ¿qué son los estados mentales?, ¿cómo son representados?, y ¿cómo nuestro cerebro nos permite entender otras mentes? se ha convertido en un tema importante para la investigación médica y psicosocial; tal hecho podría explicar el deterioro en las funciones ejecutivas y socio-emocionales (ej. dificultad del lenguaje verbal y no verbal) asociadas a ciertas condiciones neurológicas y psiquiátricas, tales como: el autismo, la esquizofrenia, la enfermedad de Alzheimer, la enfermedad de Parkinson e, incluso, la depresión. Como consecuencia ha nacido el constructo denominado “Teoría de la mente” (ToM por sus siglas en inglés), que busca explicar la capacidad mental innata para atribuir estados cognitivos a las situaciones cotidianas tanto para uno mismo (meta-cognición & meta-representación), como para otros sujetos; es decir, representa un mecanismo teórico creado para explicar la racionalidad humana dentro de un entorno social. ","PeriodicalId":34902,"journal":{"name":"Archivos de Neurociencias","volume":"21 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-11-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85418393","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Introduction: Kambo is the skin secretion of the toxic Brazilian frog Phyllomedusa bicolor and has been practiced its inoculation through the human skin worldwide, especially in South America, by curiosity or to cure multiple diseases. Objective: Report a case of poisoning in a current ritual with Kambo frog poison. Results: 41-year-old male, Marijuana user with a last consumption three months ago. He used Kambo for generalized anxiety disorder with panic attacks and claustrophobia. He suffered complications, including neuropathy, that we associate to the toxic effect of Kambo. He received oral prednisone, diphenidol and paroxetine as treatment with improvement. Discussión: The substances that can be related to the neuropathy are tachykinin through the B receptors that participate in mechanisms linked to pain, dermorphins and deltorphins, Mu opioid agonists that act on Mu and Delta receptors of the central nervous system involved in analgesic effects, exist two phases have been described in Kambo intoxication: the first phase (usually 15-30 minutes) and the second phase, that include the persistence of acute symptoms, syndrome of inappropriate antidiuretic hormone secretion, acute toxic hepatitis, and dermatomyositis. Our patient presented the classic acute symptoms, however, he had focal sensory neuropathy. Conclusion: Clinicians need to be aware of the complications of this shamanic ritual expanding worldwide.
{"title":"Kambo Frog Poisoning in Mexico","authors":"Daniel San Juan Orta, Daniel Arturo Martínez Piña","doi":"10.31157/an.v28i1.415","DOIUrl":"https://doi.org/10.31157/an.v28i1.415","url":null,"abstract":"Introduction: Kambo is the skin secretion of the toxic Brazilian frog Phyllomedusa bicolor and has been practiced its inoculation through the human skin worldwide, especially in South America, by curiosity or to cure multiple diseases. Objective: Report a case of poisoning in a current ritual with Kambo frog poison. Results: 41-year-old male, Marijuana user with a last consumption three months ago. He used Kambo for generalized anxiety disorder with panic attacks and claustrophobia. He suffered complications, including neuropathy, that we associate to the toxic effect of Kambo. He received oral prednisone, diphenidol and paroxetine as treatment with improvement. Discussión: The substances that can be related to the neuropathy are tachykinin through the B receptors that participate in mechanisms linked to pain, dermorphins and deltorphins, Mu opioid agonists that act on Mu and Delta receptors of the central nervous system involved in analgesic effects, exist two phases have been described in Kambo intoxication: the first phase (usually 15-30 minutes) and the second phase, that include the persistence of acute symptoms, syndrome of inappropriate antidiuretic hormone secretion, acute toxic hepatitis, and dermatomyositis. Our patient presented the classic acute symptoms, however, he had focal sensory neuropathy. Conclusion: Clinicians need to be aware of the complications of this shamanic ritual expanding worldwide.","PeriodicalId":34902,"journal":{"name":"Archivos de Neurociencias","volume":"61 5 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-11-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86802410","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Introduction: Olfactory problems are frequent in Parkinson disease. Their early onset relative to motor problems makes them a potential biomarker for the disease, yet no culture-specific standardized tests exist in Morocco. Aim: To use indigenous plant extracts generated in our laboratory to investigate olfactory impairment in patients with Parkinson disease. Method: Our study is a cross-sectional case-controlled analytical investigation in a group of 69 patients with Parkinson disease and another group of 66 healthy volunteers in order to assess odor threshold, odor identification, and odor discrimination in these two groups using Mentha pulegium and Lavandula latifolia extracts. Results: We found a marked decrease of the threshold of odor detection in patients compared to controls (p<0.001). A statistically significant difference was found between the ability to discriminate odors, with more patients with Parkinson disease unable to distinguish between odors (p<0.001). For the odor identification test, 70% of control subjects versus 36% of patients were able to correctly identify the test products. The difference was statistically significant (p<0.001). Conclusions: Our study points to the potential for the elaboration of a standardized smell identification screening battery using indigenous products with which patients are familiar.
{"title":"Olfactory impairment in Parkinson disease using culture-relevant products: making the case for a Moroccan Smell Identification Test (MoroSIT)","authors":"M. Chraa, Hanane Imizgue, R. Klevor, N. Kissani","doi":"10.31157/an.v28i1.368","DOIUrl":"https://doi.org/10.31157/an.v28i1.368","url":null,"abstract":"Introduction: Olfactory problems are frequent in Parkinson disease. Their early onset relative to motor problems makes them a potential biomarker for the disease, yet no culture-specific standardized tests exist in Morocco. \u0000Aim: To use indigenous plant extracts generated in our laboratory to investigate olfactory impairment in patients with Parkinson disease. \u0000Method: Our study is a cross-sectional case-controlled analytical investigation in a group of 69 patients with Parkinson disease and another group of 66 healthy volunteers in order to assess odor threshold, odor identification, and odor discrimination in these two groups using Mentha pulegium and Lavandula latifolia extracts. \u0000Results: We found a marked decrease of the threshold of odor detection in patients compared to controls (p<0.001). A statistically significant difference was found between the ability to discriminate odors, with more patients with Parkinson disease unable to distinguish between odors (p<0.001). For the odor identification test, 70% of control subjects versus 36% of patients were able to correctly identify the test products. The difference was statistically significant (p<0.001). \u0000Conclusions: Our study points to the potential for the elaboration of a standardized smell identification screening battery using indigenous products with which patients are familiar.","PeriodicalId":34902,"journal":{"name":"Archivos de Neurociencias","volume":"84 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79728663","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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