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Modelling of an Adjustable Generic Simplified Vehicle for Pedestrian Impact and Simulations of Corresponding Reference PMHS Tests Using the GHBMC 50th Percentile Male Pedestrian Simplified Model. 基于GHBMC第50百分位男性行人简化模型的可调节通用简化车辆行人碰撞建模及相应参考PMHS测试仿真
Q2 Medicine Pub Date : 2018-11-01 DOI: 10.4271/2018-22-0013
Eric Song, Philippe Petit, Jerome Uriot

In a previous study (Song et al. 2017), an adjustable generic simplified vehicle buck was developed; eleven PMHS were impacted by the buck representing a SUV, a van and a sedan successively; and biofidelity corridors were established. The objectives of the current study were 1) to develop the computational model of the buck, and 2) to simulate these PMHS tests with the buck model and to assess the biofidelity of the GHBMC 50th percentile male pedestrian simplified model (GHBMC M50-PS). First, coupon tensile tests and static and dynamic compression tests were performed on the steel tubes representing the bonnet leading edge (BLE), the bumper and the spoiler used in the above PMHS tests. Based on these tests, the computational models of the above components were then developed and validated. Next, the buck model was built with the component models, and used to simulate the PMHS tests with the GHBMC M50-PS model. These simulations allowed to evaluate the biofidelity of the GHBMC M50-PS model in terms of 1) impact forces between the pedestrian and the buck, 2) pedestrian kinematics, and 3) injury outcome resulted. The model well predicted the total longitudinal impact force between the pedestrian and the buck for all three vehicle types, with a total CORA score between 0.72 and 0.78. However, the force distribution across the BLE, bumper and spoiler showed some significant deviations. The kinematic response of the model was rated as fair with a total CORA score ranging between 0.52 and 0.58. It seems necessary to increase the compliance of the GHBMC M50-PS model and its energy dissipation capability in order to achieve a better correlation of its kinematic response. Finally, the model predicted more knee ligament ruptures than observed in the PMHS tests, but less bone fracture of the femur and the fibula.

在之前的一项研究中(Song et al. 2017),开发了一种可调节的通用简化车辆buck;11名PMHS依次受到代表SUV、面包车和轿车的雄鹿的影响;并建立了生物保真走廊。本研究的目的是:(1)建立buck的计算模型;(2)用buck模型模拟PMHS测试,并评估GHBMC第50百分位男性行人简化模型(GHBMC M50-PS)的生物保真度。首先,对上述PMHS试验中使用的代表发动机罩前缘(BLE)、保险杠和扰流板的钢管进行了联片拉伸试验和静态和动态压缩试验。在这些试验的基础上,建立并验证了上述构件的计算模型。其次,利用构件模型建立buck模型,并利用GHBMC M50-PS模型对PMHS试验进行仿真。这些模拟可以从以下几个方面评估GHBMC M50-PS模型的生物保真度:1)行人与雄鹿之间的冲击力,2)行人运动学,以及3)损伤结果。该模型较好地预测了三种车型的行人与雄鹿之间的总纵向冲击力,总CORA得分在0.72 ~ 0.78之间。然而,在低挡板、保险杠和扰流板上的力分布表现出一些显著的偏差。模型的运动响应被评为公平,总CORA得分在0.52到0.58之间。为了获得更好的运动学响应相关性,有必要提高GHBMC M50-PS模型的柔度和耗能能力。最后,该模型预测的膝关节韧带破裂比PMHS试验中观察到的更多,但股骨和腓骨骨折较少。
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引用次数: 0
Quantification of Skeletal and Soft Tissue Contributions to Thoracic Response in a Dynamic Frontal Loading Scenario. 在动态正面载荷情况下,骨骼和软组织对胸部反应的量化。
Q2 Medicine Pub Date : 2018-11-01 DOI: 10.4271/2018-22-0005
Michelle M Murach, Yun-Seok Kang, John H Bolte, David Stark, Rakshit Ramachandra, Amanda M Agnew, Kevin Moorhouse, Jason Stammen

Thoracic injuries continue to be a major health concern in motor vehicle crashes. Previous thoracic research has focused on 50th percentile males and utilized scaling techniques to apply results to different demographics. Individual rib testing offers the advantage of capturing demographic differences; however, understanding of rib properties in the context of the intact thorax is lacking. Therefore, the objective of this study was to obtain the data necessary to develop a transfer function between individual rib and thoracic response. A series of non-injurious frontal impacts were conducted on six PMHS, creating a loading environment commensurate to previously published individual rib testing. Each PMHS was tested in four tissue states: intact, intact with upper limbs removed, denuded, and eviscerated. Following eviscerated thoracic testing, eight individual mid-level ribs from each PMHS were removed and loaded to failure. A simplified model in which ribs of each thorax are treated as parallel springs was utilized to evaluate the ability of individual rib response data to predict each subject's eviscerated thoracic response. On average across subjects, denuded thoraces retained 89% and eviscerated thoraces retained 46% of intact force. Similarly, denuded thoraces retained 70% and eviscerated thoraces retained 30% of intact stiffness. The rib model did not adequately predict eviscerated thoracic response but provided a better understanding of the influence of connective tissue on a rib's behavior with-in the thorax. Results of this study could be used in conjunction with the database of individual rib test results to improve thoracic response targets and help assess biofidelity of current anthropomorphic test devices.

在机动车碰撞事故中,胸部损伤仍然是一个主要的健康问题。以前的胸部研究主要集中在第50百分位的男性,并利用缩放技术将结果应用于不同的人口统计学。单个肋骨测试提供了捕捉人口统计学差异的优势;然而,在完整胸腔的背景下,对肋骨特性的理解是缺乏的。因此,本研究的目的是获得必要的数据,以建立个体肋骨和胸部反应之间的传递函数。在6个PMHS上进行了一系列非伤害性正面碰撞,创造了与先前发表的单个肋骨测试相称的加载环境。每个PMHS在四种组织状态下进行测试:完整,完整上肢切除,剥落和内脏。在切除胸腔试验之后,从每个PMHS中取出8根独立的中层肋骨并加载至失效。一个简化的模型,其中每个胸腔的肋骨被视为平行弹簧,用来评估单个肋骨反应数据的能力,以预测每个受试者的全胸反应。在所有受试者中,平均而言,剥去的胸腔保留了89%的完整力,而剔除的胸腔保留了46%的完整力。同样,剥去的胸部保留了70%的完整刚度,去内脏的胸部保留了30%的完整刚度。肋骨模型不能充分预测胸腔内的全膛反应,但可以更好地理解结缔组织对胸腔内肋骨行为的影响。本研究结果可与单个肋骨试验结果数据库结合使用,以提高胸部反应指标,并有助于评估当前拟人试验装置的生物保真度。
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引用次数: 6
Human Shoulder Response to Lateral Impact in Intermediate Loading Conditions Between High-Velocity, Short-Duration and Low-Velocity, Long-Duration. 在高速、短时间和低速、长时间之间的中间负载条件下,人体肩部对横向冲击的反应。
Q2 Medicine Pub Date : 2018-11-01 DOI: 10.4271/2018-22-0008
Matthieu Lebarbé, Pascal Potier, Jérôme Uriot, Pascal Baudrit, Denis Lafont, Richard Douard

The EuroSID-2re (ES-2re) Anthropomorphic Test Device (ATD) commonly known as the crash test dummy is also used in the military domain to assess the risk of injury of armored vehicles occupants from lateral impact. The loading conditions range from low velocity - long duration impacts (4 m/s - 50 ms) similar to the automotive domain, to high velocity - short duration impacts (28 m/s - 3 ms) corresponding to cases where the panel deforms under an explosion. The human shoulder response to lateral impact was investigated at bounds of the loading condition spectrum previously mentioned, and also at intermediate conditions (14 m/s - 9 ms) in previous studies. The aim of the current study is to provide additional insight at the intermediate loading conditions which are not found in the literature. Eight pure lateral shoulder impact tests were performed on Post Mortem Human Subjects (PMHS) using an 8.1 kg rigid impactor at velocities ranging from 3.3 m/s to 8.8 m/s with the duration ranging from 25 ms to 35 ms. The PMHS were instrumented with accelerometers attached to the sternum, and the upper thoracic spine (T1 vertebra). Strain gages were glued onto the right and left clavicles and ribs 2 to 6. The shoulder force was measured at the interface with the impactor and the impact was filmed by high speed cameras (5000 fps) to track the YZ displacements of the impactor, T1 vertebra, and sternum in the laboratory frame. Three shoulders out of the eight sustained AIS 2 injuries which included a clavicle fracture. The impactor forces ranged from 1200 to 4600 N. The PMHS accelerations ranged from 44 to 163 g at the sternum, and from 17 to 60 g at the T1 vertebra. The analysis of the strain gage signals revealed that the clavicle fractures occurred at the beginning of the impact and coincided with a peak force. An estimate of the acromion-to-shoulder compression (Cmax) was computed. It ranged from 0% to 15% for the non-injured shoulders, and from 19% to 28% for the injured shoulders. This new PMHS test series will be used in a future work to develop a shoulder injury criterion for the ES-2re ATD that is relevant for the whole loading conditions spectrum of the military domain.

EuroSID-2re (ES-2re)拟人化试验装置(ATD)通常被称为碰撞试验假人,也用于军事领域评估装甲车辆乘员受横向冲击伤害的风险。加载条件范围从低速-长时间冲击(4米/秒- 50毫秒),类似于汽车领域,到高速-短时间冲击(28米/秒- 3毫秒),对应于面板在爆炸下变形的情况。在前面提到的加载条件谱的边界上,以及在先前的研究中,在中间条件(14 m/s - 9 ms)下,研究了人类肩膀对侧向冲击的反应。当前研究的目的是在文献中未发现的中间加载条件下提供额外的见解。使用8.1 kg的刚性撞击器,在3.3 m/s至8.8 m/s的速度范围内,持续时间为25 ms至35 ms,对死后人体受试者(PMHS)进行了8次纯侧肩撞击试验。PMHS采用附着在胸骨和上胸椎(T1椎体)上的加速度计进行检测。应变计粘在左右锁骨和肋骨2至6上。在实验室框架中,测量与撞击器界面处的肩部力,并通过高速摄像机(5000 fps)拍摄撞击过程,以跟踪撞击器、T1椎体和胸骨的YZ位移。8名患者中有3名肩部持续AIS 2型损伤,其中包括锁骨骨折。撞击力范围为1200至4600牛顿。PMHS在胸骨处的加速度范围为44至163克,在T1椎体处的加速度范围为17至60克。对应变计信号的分析显示锁骨骨折发生在撞击开始时,并与峰值力相吻合。计算肩峰对肩压(Cmax)的估计。未受伤的肩膀从0%到15%不等,受伤的肩膀从19%到28%不等。这个新的PMHS测试系列将在未来的工作中用于为ES-2re ATD制定肩伤标准,该标准与军事领域的整个加载条件谱相关。
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引用次数: 2
Sources of Variability in Structural Bending Response of Pediatric and Adult Human Ribs in Dynamic Frontal Impacts. 儿童和成人肋骨在动态正面碰撞中结构弯曲反应的变异性来源。
Q2 Medicine Pub Date : 2018-11-01 DOI: 10.4271/2018-22-0004
Amanda M Agnew, Michelle M Murach, Victoria M Dominguez, Akshara Sreedhar, Elina Misicka, Angela Harden, John H Bolte, Yun-Seok Kang, Jason Stammen, Kevin Moorhouse

Despite safety advances, thoracic injuries in motor vehicle crashes remain a significant source of morbidity and mortality, and rib fractures are the most prevalent of thoracic injuries. The objective of this study was to explore sources of variation in rib structural properties in order to identify sources of differential risk of rib fracture between vehicle occupants. A hierarchical model was employed to quantify the effects of demographic differences and rib geometry on structural properties including stiffness, force, displacement, and energy at failure and yield. Three-hundred forty-seven mid-level ribs from 182 individual anatomical donors were dynamically (~2 m/s) tested to failure in a simplified bending scenario mimicking a frontal thoracic impact. Individuals ranged in age from 4 - 108 years (mean 53 ± 23 years) and included 59 females and 123 males of diverse body sizes. Age, sex, body size, aBMD, whole rib geometry and cross-sectional geometry were explored as predictors of rib structural properties. Measures of cross-sectional rib size (Tt.Ar), bone quantity (Ct.Ar), and bone distribution (Z) generally explained more variation than any other predictors, and were further improved when normalized by rib length (e.g., robustness and WBSI). Cortical thickness (Ct.Th) was not found to be a useful predictor. Rib level predictors performed better than individual level predictors. These findings moderately explain differential risk for rib fracture and with additional exploration of the rib's role in thoracic response, may be able contribute to ATD and HBM development and alterations in addition to improvements to thoracic injury criteria and scaling methods.

尽管安全性有所提高,但机动车碰撞中的胸部损伤仍然是发病率和死亡率的重要来源,而肋骨骨折是最常见的胸部损伤。本研究的目的是探索肋骨结构特性变异的来源,以确定车辆乘员肋骨骨折风险差异的来源。采用分层模型来量化人口统计学差异和肋形对结构特性的影响,包括刚度、力、位移、破坏和屈服时的能量。来自182个个体解剖供体的347根中间节肋骨在模拟胸部正面撞击的简化弯曲场景中动态(~ 2m /s)测试失败。个体年龄4 ~ 108岁(平均53±23岁),包括59名女性和123名男性,体型不同。年龄,性别,体型,aBMD,整个肋骨几何形状和横截面几何形状作为肋骨结构特性的预测因子进行了探讨。横截面肋骨尺寸(Tt.Ar)、骨量(Ct.Ar)和骨分布(Z)的测量值通常比任何其他预测因子解释了更多的变化,并且当通过肋骨长度(例如,稳健性和WBSI)进行归一化时进一步得到改善。皮质厚度(Ct.Th)并不是一个有用的预测因子。肋骨水平预测比个体水平预测效果更好。这些发现适度地解释了肋骨骨折的不同风险,并进一步探讨了肋骨在胸部反应中的作用,除了改进胸部损伤标准和评分方法外,还可能有助于ATD和HBM的发展和改变。
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引用次数: 33
A Reanalysis of Experimental Brain Strain Data: Implication for Finite Element Head Model Validation. 脑应变实验数据的再分析:对有限元头部模型验证的启示。
Q2 Medicine Pub Date : 2018-11-01 DOI: 10.4271/2018-22-0007
Zhou Zhou, Xiaogai Li, Svein Kleiven, Chirag S Shah, Warren N Hardy

Relative motion between the brain and skull and brain deformation are biomechanics aspects associated with many types of traumatic brain injury (TBI). Thus far, there is only one experimental endeavor (Hardy et al., 2007) reported brain strain under loading conditions commensurate with levels that were capable of producing injury. Most of the existing finite element (FE) head models are validated against brain-skull relative motion and then used for TBI prediction based on strain metrics. However, the suitability of using a model validated against brain-skull relative motion for strain prediction remains to be determined. To partially address the deficiency of experimental brain deformation data, this study revisits the only existing dynamic experimental brain strain data and updates the original calculations, which reflect incremental strain changes. The brain strain is recomputed by imposing the measured motion of neutral density target (NDT) to the NDT triad model. The revised brain strain and the brain-skull relative motion data are then used to test the hypothesis that an FE head model validated against brainskull relative motion does not guarantee its accuracy in terms of brain strain prediction. To this end, responses of brain strain and brain-skull relative motion of a previously developed FE head model (Kleiven, 2007) are compared with available experimental data. CORrelation and Analysis (CORA) and Normalized Integral Square Error (NISE) are employed to evaluate model validation performance for both brain strain and brain-skull relative motion. Correlation analyses (Pearson coefficient) are conducted between average cluster peak strain and average cluster peak brain-skull relative motion, and also between brain strain validation scores and brain-skull relative motion validation scores. The results show no significant correlations, neither between experimentally acquired peaks nor between computationally determined validation scores. These findings indicate that a head model validated against brain-skull relative motion may not be sufficient to assure its strain prediction accuracy. It is suggested that a FE head model with intended use for strain prediction should be validated against the experimental brain deformation data and not just the brain-skull relative motion.

脑与颅骨之间的相对运动和脑变形是与许多类型的创伤性脑损伤(TBI)相关的生物力学方面的问题。到目前为止,只有一项实验(Hardy et al., 2007)报道了与能够产生损伤的水平相称的负载条件下的脑疲劳。现有的有限元头部模型大多是根据脑-颅骨相对运动进行验证,然后用于基于应变指标的TBI预测。然而,使用针对脑-颅骨相对运动的模型进行应变预测的适用性仍有待确定。为了部分解决脑变形实验数据的不足,本研究重新审视了仅有的动态脑应变实验数据,并更新了反映增量应变变化的原始计算。通过将测量到的中性密度靶(NDT)运动施加到NDT三元模型中,重新计算脑应变。修正后的脑劳损和脑-颅骨相对运动数据被用来检验脑-颅骨相对运动验证的FE头部模型在脑劳损预测方面不能保证准确性的假设。为此,将先前开发的FE头部模型(Kleiven, 2007)的脑应变反应和脑-颅骨相对运动与现有实验数据进行比较。采用相关分析(CORA)和归一化积分平方误差(NISE)对脑劳损和脑-颅相对运动模型验证性能进行评价。对平均簇峰应变与平均簇峰脑-颅骨相对运动、脑应变验证分数与脑-颅骨相对运动验证分数进行Pearson相关分析。结果显示,无论是在实验获得的峰值之间,还是在计算确定的验证分数之间,都没有显著的相关性。这些发现表明,针对脑-颅骨相对运动验证的头部模型可能不足以保证其应变预测的准确性。作者建议,一个用于应变预测的头部有限元模型应该根据实验脑变形数据进行验证,而不仅仅是脑-颅相对运动。
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引用次数: 43
Analysis of Repeatability and Reproducibility Standards of ATD Response for the Correlation Method. 相关法ATD响应的重复性和再现性标准分析。
Q2 Medicine Pub Date : 2017-11-01 DOI: 10.4271/2017-22-0010
Lan Xu, Guy Nusholtz

Statistical methods, using the entire time-history, can be used to assess the impact response of an ATD (Anthropomorphic Test Device) in terms of its repeatability and reproducibility. In general, the methods generate a correlation relationship described as shape, magnitude and phase-difference between two time-histories' in a given set of similar tests: for repeatability the relationship it is for the same ATD, for reproducibility it is for different ATDs of the same design and for biofidelity it is a relationship between ATDs and biomechanical response data from a series of human surrogate impact tests. The method uses the phase relationship to minimize the difference between any two time-histories through an alignment procedure and the magnitude and shape correlations are used to generate a parametric evaluation of the differences between any two time-histories, or set of time-histories. This paper introduces a variance analysis using the entire time history to build additional foundation to the parametric evaluations using the magnitude and shape correlations and how they can be used to define repeatability and reproducibility ratings/criterion. The proposed methodology has been evaluated using two data sets based on HIII 50th dummy's chest acceleration time histories observed in USNCAP tests. The first set consists of five tests from a single Lab. The second set consists of seven tests from labs different from the first set. A time-history parameter, V, (the normalized summation of squared point to point difference between a pair of signals) was introduced and used to perform statistical analysis of Variance (ANOVA) of the reproducibility of the time histories under investigation. In particular, the V-parameter has been analyzed using both ANOVA and T-test approaches. The relationship between the parameter V and the parameters shape correlation and magnitude correlation is derived analytically. Using this relationship, criterions have been defined for reproducibility and/or repeatability with respect to the shape and magnitude correlations metrics. The criterions have been developed using a limited data set and may change as more data becomes available and is analyzed.

统计方法,使用整个时间历史,可用于评估ATD(拟人化测试装置)的可重复性和再现性的冲击响应。一般来说,这些方法在给定的一组类似试验中产生一种相关关系,称为“两个时程之间的形状、幅度和相位差”:对于可重复性,它是针对同一ATD的关系;对于可重复性,它是针对相同设计的不同ATD的关系;对于生物保真度,它是ATD与一系列人体替代冲击试验的生物力学响应数据之间的关系。该方法使用相位关系,通过校准程序最小化任意两个时程之间的差异,并使用幅度和形状相关性来生成任意两个时程或一组时程之间差异的参数评估。本文介绍了使用整个时间历史的方差分析,以使用幅度和形状相关性为参数评估建立额外的基础,以及如何使用它们来定义可重复性和可再现性评级/标准。根据USNCAP测试中观察到的HIII 50假人胸部加速时间史,使用两个数据集对所提出的方法进行了评估。第一组包括来自单个实验室的五项测试。第二组包括来自不同于第一组的实验室的七项测试。引入时程参数V(一对信号之间点对点差平方的归一化和),并用于对所调查时程的可重复性进行方差统计分析(ANOVA)。特别是,使用方差分析和t检验方法对v参数进行了分析。导出了参数V与参数形状相关和大小相关之间的关系。利用这种关系,定义了关于形状和大小相关指标的再现性和/或可重复性的标准。这些标准是使用有限的数据集制定的,并可能随着更多的数据可用和分析而改变。
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引用次数: 1
Human Shoulder Response to High Velocity Lateral Impact. 人体肩部对高速侧面撞击的反应。
Q2 Medicine Pub Date : 2017-11-01 DOI: 10.4271/2017-22-0002
Matthieu Lebarbé, Philippe Vezin, Frédéric Rongiéras, Denis Lafont

The armies of the North Atlantic Treaty Organization need a shoulder injury criterion for the EuroSID-2re dummy that must be reliable over a large range of loading conditions, from high velocity, short duration impacts (28 m/s - 3 ms) to low velocity long, duration impacts (4 m/s - 50 ms). In the literature, the human shoulder response to lateral impact was investigated at bounds of the loading condition spectrum as previously mentioned. For the low velocities, the injuries were mainly clavicle fractures and the maximum compression between the acromion and the sternum (Cmax) was proposed as an injury criterion. For the high velocities, the typical injury was humerus fractures, including a crushed humeral head. The present study investigates the human shoulder response at an intermediate loading condition (14 m/s - 9 ms). Six lateral shoulder impact tests have been performed with three Post Mortem Human Subjects using a rigid impactor. The duration of the impact was controlled by means of an aluminum honeycomb that decelerated the impactor during the impact. The shoulder external deflection (impactor-to-sternum) ranged between 40 to 64 mm and the applied forces ranged from 4.3 kN to 8 kN. Four shoulders out of six sustained AIS2 injuries. Two acromio-clavicular joint dislocations, one clavicle fracture, and one scapula fracture were observed. Though the shoulder force responses were closer to those induced by the high velocity, short duration impacts, the injury patterns resembled those observed for low velocity, long duration loading conditions. Furthermore, the estimated acromion-to-sternum deflection values were not inconsistent with the prediction of the shoulder injury risk curve of the literature. Despite the relatively high-velocity impact (14.3 m/s), the shoulder injury mechanism appeared to be similar to those observed in the automotive field.

北大西洋公约组织的军队需要EuroSID-2re假人的肩伤标准,该标准必须在大范围的载荷条件下可靠,从高速,短时间撞击(28米/秒- 3毫秒)到低速,长时间撞击(4米/秒- 50毫秒)。在文献中,如前所述,在加载条件谱的边界处研究了人类肩部对侧向冲击的反应。低速时,损伤以锁骨骨折为主,建议以肩峰与胸骨间最大压缩量(Cmax)作为损伤标准。对于高速,典型的损伤是肱骨骨折,包括肱骨头粉碎。本研究探讨了人体肩部在中等负荷条件下(14米/秒- 9毫秒)的反应。使用刚性冲击器对三名死后人体受试者进行了六次侧肩冲击试验。撞击的持续时间是通过铝蜂窝来控制的,在撞击过程中,铝蜂窝使撞击器减速。肩部外部偏转(冲击器到胸骨)范围为40至64毫米,施加力范围为4.3至8千牛。六名患者中有四名肩部持续AIS2损伤。2例肩锁关节脱位,1例锁骨骨折,1例肩胛骨骨折。虽然肩部力响应更接近于高速、短时间冲击引起的,但损伤模式与低速、长时间加载条件下观察到的损伤模式相似。此外,估计的肩峰到胸骨挠度值与文献中预测的肩部损伤风险曲线并不矛盾。尽管碰撞速度相对较高(14.3 m/s),但肩部损伤机制似乎与汽车领域观察到的相似。
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引用次数: 1
New Reference PMHS Tests to Assess Whole-Body Pedestrian Impact Using a Simplified Generic Vehicle Front-End. 使用简化的通用车辆前端评估全身行人影响的新参考PMHS测试
Q2 Medicine Pub Date : 2017-11-01 DOI: 10.4271/2017-22-0012
Eric Song, Philippe Petit, Xavier Trosseille, Jerome Uriot, Pascal Potier, Denis Dubois, Richard Douard

This study aims to provide a set of reference post-mortem human subject tests which can be used, with easily reproducible test conditions, for developing and/or validating pedestrian dummies and computational human body models against a road vehicle. An adjustable generic buck was first developed to represent vehicle front-ends. It was composed of four components: two steel cylindrical tubes screwed on rigid supports in V-form represent the bumper and spoiler respectively, a quarter of a steel cylindrical tube represents the bonnet leading edge, and a steel plate represents the bonnet. These components were positioned differently to represent three types of vehicle profile: a sedan, a SUV and a van. Eleven post-mortem human subjects were then impacted laterally in a mid-gait stance by the bucks at 40 km/h: three tests with the sedan, five with the SUV, and three with the van. Kinematics of the subjects were recorded via high speed videos, impact forces between the subjects and the bucks were measured via load cells behind each tube, femur and tibia deformation and fractures were monitored via gauges on these bones. Based on these tests, biofidelity corridors were established in terms of: 1) displacement time history and trajectory of the head, shoulder, T1, T4, T12, sacrum, knee and ankle, 2) impact forces between the subjects and the buck. Injury outcome was established for each PMHS via autopsy. Simplicity of its geometry and use of standard steel tubes and plates for the buck will make it easy to perform future, new post-mortem human subject tests in the same conditions, or to assess dummies or computational human body models using these reference tests.

本研究旨在提供一套可用于开发和/或验证行人假人以及针对道路车辆的计算人体模型的可重复测试条件的参考死后人体受试者测试。一个可调的通用buck首先被开发来代表车辆前端。它由四个部分组成:两根钢圆柱管拧在刚性支架上,呈v形分别代表保险杠和扰流板,四分之一的钢圆柱管代表阀盖前缘,一块钢板代表阀盖。这些部件的位置不同,代表了三种类型的车辆轮廓:轿车、SUV和面包车。11名死后的人类受试者被雄鹿以40公里/小时的速度以中等姿态横向撞击:3次用轿车,5次用SUV, 3次用货车。通过高速视频记录受试者的运动学,通过每根管子后面的称重传感器测量受试者和雄鹿之间的冲击力,通过这些骨头上的仪表监测股骨和胫骨的变形和骨折。在此基础上,根据1)头部、肩部、T1、T4、T12、骶骨、膝关节和踝关节的位移时间历史和轨迹,2)受试者与雄鹿之间的冲击力,建立生物保真走廊。通过尸检确定每个PMHS的损伤结果。它的几何结构简单,使用标准的钢管和钢板,这将使它易于在相同的条件下进行未来新的死后人体试验,或使用这些参考试验来评估假人或计算人体模型。
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引用次数: 5
Strain-Rate Dependency of Axonal Tolerance for Uniaxial Stretching. 单轴拉伸轴突公差的应变率依赖性。
Q2 Medicine Pub Date : 2017-11-01 DOI: 10.4271/2017-22-0003
Hiromichi Nakadate, Evrim Kurtoglu, Hidenori Furukawa, Shoko Oikawa, Shigeru Aomura, Akira Kakuta, Yasuhiro Matsui

This study aims to clarify the relation between axonal deformation and the onset of axonal injury. Firstly, to examine the influence of strain rate on the threshold for axonal injury, cultured neurons were subjected to 12 types of stretching (strains were 0.10, 0.15, and 0.20 and strain rates were 10, 30, 50, and 70 s-1). The formation of axonal swellings and bulbs increased significantly at strain rates of 50 and 30 s-1 with strains of 0.15 and 0.20, respectively, even though those formations did not depend on strain rates in cultures exposed to a strain of 0.10. Then, to examine the influence of the strain along an axon on axonal injury, swellings were measured at every axonal angle in the stretching direction. The axons that were parallel to stretching direction were injured the most. Finally, we proposed an experimental model that subjected an axon to more accurate strain. This model observed the process of axonal injury formation by detecting the same neuron before and after stretching. These results suggest that the strain-rate dependency of axonal tolerance is induced by a higher magnitude of loading strain and an experiment focusing on axonal strain is required for obtaining more detailed injury criteria for an axon.

本研究旨在阐明轴突变形与轴突损伤发生的关系。首先,为了研究应变速率对轴突损伤阈值的影响,我们对培养的神经元进行了12种拉伸(应变分别为0.10、0.15和0.20,应变速率分别为10、30、50和70 s-1)。当菌株分别为0.15和0.20时,轴突肿胀和鳞茎的形成在菌株速率为50和30 s-1时显著增加,尽管在菌株暴露于0.10时,这些形成与菌株速率无关。然后,为了检查沿轴突应变对轴突损伤的影响,在拉伸方向的每个轴突角度测量肿胀。与拉伸方向平行的轴突损伤最大。最后,我们提出了一个实验模型,使轴突受到更精确的应变。该模型通过检测拉伸前后同一神经元,观察轴突损伤的形成过程。这些结果表明,轴突耐受性的应变速率依赖性是由较大的加载应变引起的,需要对轴突应变进行实验,以获得更详细的轴突损伤标准。
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引用次数: 12
Biomechanics of Lumbar Motion-Segments in Dynamic Compression. 动态压缩腰椎运动节段的生物力学。
Q2 Medicine Pub Date : 2017-11-01 DOI: 10.4271/2017-22-0001
Mike W J Arun, Prasannaah Hadagali, Klaus Driesslein, William Curry, Narayan Yoganandan, Frank A Pintar

Recent epidemiology studies have reported increase in lumbar spine injuries in frontal crashes. Whole human body finite element models (FEHBM) are frequently used to delineate mechanisms of such injuries. However, the accuracy of these models in mimicking the response of human spine relies on the characterization data of the spine model. The current study set out to generate characterization data that can be input to FEHBM lumbar spine, to obtain biofidelic responses from the models. Twenty-five lumbar functional spinal units were tested under compressive loading. A hydraulic testing machine was used to load the superior ends of the specimens. A 75N load was placed on the superior PMMA to remove the laxity in the joint and mimic the physiological load. There were three loading sequences, namely, preconditioning, 0.5 m/s (non-injurious) and 1.0 m/s (failure). Forces and displacements were collected using six-axis load cell and VICON targets. In addition, acoustic signals were collected to identify the times of failures. Finally, response corridors were generated for the two speeds. To demonstrate the corridors, GHBMC FE model was simulated in frontal impact condition with the default and updated lumbar stiffness. Bi-linear trend was observed in the force versus displacement plots. In the 0.5 m/s tests, mean toe- and linear-region stiffnesses were 0.96±0.37 and 2.44±0.92 kN/mm. In 1.0 m/s tests, the toe and linear-region stiffnesses were 1.13±0.56 and 4.6±2.5 kN/mm. Lumbar joints demonstrated 2.5 times higher stiffness in the linear-region when the loading rate was increased by 0.5 m/s.

最近的流行病学研究报告了前部碰撞中腰椎损伤的增加。整个人体有限元模型(FEHBM)经常被用来描述这种损伤的机制。然而,这些模型在模拟人类脊柱反应时的准确性依赖于脊柱模型的表征数据。目前的研究旨在生成可输入FEHBM腰椎的特征数据,以从模型中获得生物特异性反应。在压缩载荷下测试了25个腰椎功能脊柱单元。采用水力试验机对试件上端进行加载。在上部PMMA上施加75N的载荷以消除关节松弛并模拟生理载荷。加载顺序分别为预处理、0.5 m/s(无损伤)和1.0 m/s(失效)。使用六轴称重传感器和VICON靶收集力和位移。此外,还收集了声信号来识别故障次数。最后,为两种速度生成响应走廊。为了证明这些通道,在正面碰撞条件下,采用默认和更新的腰椎刚度模拟了GHBMC FE模型。在力-位移图中观察到双线性趋势。在0.5 m/s的测试中,脚趾和线性区域的平均刚度分别为0.96±0.37和2.44±0.92 kN/mm。在1.0 m/s试验中,趾部和线性区域刚度分别为1.13±0.56和4.6±2.5 kN/mm。加载速率每增加0.5 m/s,腰椎关节线性区刚度提高2.5倍。
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引用次数: 9
期刊
Stapp car crash journal
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