Pub Date : 2021-01-01DOI: 10.5935/1676-2444.20210001
R. B. Leite, A. C. O. Marinho, Beatriz L. Costa, Maria Beatriz V. Laranjeira, K. M. D. Araújo, A. Cavalcanti
In Brazil, smoking and drinking are more common in male patients, less frequently affecting female patients. The most diagnosed type of lesion is squamous cell carcinoma. This article aims to understand the literary references associated with the influence of tobacco and alcohol on the development of oral cavity cancer. In order to elaborate an analytical and thematic literature review, using the Literatura Latino-Americana e do Caribe em Ciências da Saúde (Lilacs), Scientific Electronic Library Online (Scielo), US National Library of Medicine National Institutes of Health (PubMed) and Medline databases, articles from the English and Portuguese literatures published between 2007 and 2019 were searched with the help of the terms: prognostic factors and indicators, tobacco, alcohol and oral carcinoma. Proper knowledge of the disease and its etiological and prognostic factors should make professionals able to prevent, identify and control oral cancer.
在巴西，吸烟和饮酒在男性患者中更为常见，而对女性患者的影响较少。诊断最多的病变类型是鳞状细胞癌。本文旨在了解烟草和酒精对口腔癌发展影响的相关文献。为了详细分析和专题文献综述，使用Literatura latin - americana e do Caribe em Ciências da Saúde (Lilacs)、科学电子图书馆在线(Scielo)、美国国家医学图书馆国立卫生研究院(PubMed)和Medline数据库，检索了2007年至2019年期间发表的英语和葡萄牙语文献中的文章，检索词为:预后因素和指标、烟草、酒精和口腔癌。对口腔癌及其病因和预后因素的适当了解应使专业人员能够预防、识别和控制口腔癌。
{"title":"The influence of tobacco and alcohol in oral cancer: literature review","authors":"R. B. Leite, A. C. O. Marinho, Beatriz L. Costa, Maria Beatriz V. Laranjeira, K. M. D. Araújo, A. Cavalcanti","doi":"10.5935/1676-2444.20210001","DOIUrl":"https://doi.org/10.5935/1676-2444.20210001","url":null,"abstract":"In Brazil, smoking and drinking are more common in male patients, less frequently affecting female patients. The most diagnosed type of lesion is squamous cell carcinoma. This article aims to understand the literary references associated with the influence of tobacco and alcohol on the development of oral cavity cancer. In order to elaborate an analytical and thematic literature review, using the Literatura Latino-Americana e do Caribe em Ciências da Saúde (Lilacs), Scientific Electronic Library Online (Scielo), US National Library of Medicine National Institutes of Health (PubMed) and Medline databases, articles from the English and Portuguese literatures published between 2007 and 2019 were searched with the help of the terms: prognostic factors and indicators, tobacco, alcohol and oral carcinoma. Proper knowledge of the disease and its etiological and prognostic factors should make professionals able to prevent, identify and control oral cancer.","PeriodicalId":35397,"journal":{"name":"Jornal Brasileiro de Patologia e Medicina Laboratorial","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71117318","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.5935/1676-2444.20210008
José Luiz de Oliveira Magalhães, A. A. Araújo, Leonardo Dias Magalhães da Silva, Ilyana Oliveira Coutinho, Juliana Figueirêdo da Costa Lima, N. Leal, A. Almeida
{"title":"Bleach-concentrated direct sputum smear microscopy procedure for diagnosis of pulmonary tuberculosis in poverty areas","authors":"José Luiz de Oliveira Magalhães, A. A. Araújo, Leonardo Dias Magalhães da Silva, Ilyana Oliveira Coutinho, Juliana Figueirêdo da Costa Lima, N. Leal, A. Almeida","doi":"10.5935/1676-2444.20210008","DOIUrl":"https://doi.org/10.5935/1676-2444.20210008","url":null,"abstract":"","PeriodicalId":35397,"journal":{"name":"Jornal Brasileiro de Patologia e Medicina Laboratorial","volume":"57 1","pages":"1-8"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71118006","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.5935/1676-2444.20210026
C. M. Barros, A. P. Silva, J. O. S. S. Mizael, Y. Oshima-Franco
{"title":"Use of different matrices to construct the standard curve for the paracetamol dosage by visible spectrophotometry","authors":"C. M. Barros, A. P. Silva, J. O. S. S. Mizael, Y. Oshima-Franco","doi":"10.5935/1676-2444.20210026","DOIUrl":"https://doi.org/10.5935/1676-2444.20210026","url":null,"abstract":"","PeriodicalId":35397,"journal":{"name":"Jornal Brasileiro de Patologia e Medicina Laboratorial","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71118111","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.5935/1676-2444.20210027
N. B. Barcelos, V. G. Souza, Natália Assis, S. A. Pinto, P. H. Carvalho, C. S. S. Miranda, Aparecida de Lourdes Carvalho
{"title":"Clinicopathological study of cystic and atypical uterine leiomyoma: a rare entity","authors":"N. B. Barcelos, V. G. Souza, Natália Assis, S. A. Pinto, P. H. Carvalho, C. S. S. Miranda, Aparecida de Lourdes Carvalho","doi":"10.5935/1676-2444.20210027","DOIUrl":"https://doi.org/10.5935/1676-2444.20210027","url":null,"abstract":"","PeriodicalId":35397,"journal":{"name":"Jornal Brasileiro de Patologia e Medicina Laboratorial","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71118170","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.5935/1676-2444.20210021
Thalia Medeiros, F. R. Carvalho, R. Faustino, G. M. C. Guimarães, L. S. Alves, Any Caroline Oliveira, E. Azeredo, J. R. Almeida, L. Pinto, A. A. Silva
ABSTRACT Introduction: Studies suggest the association between antibody production and the severity of coronavirus disease 2019 (Covid-19). Objectives: To evaluate the concentrations of immunoglobulins class A (IgA) and class G (IgG) during the hospitalization period of Covid-19 patients according to the outcome (survival vs death). Materials and methods: Patients with severe acute respiratory syndrome of coronavirus 2 (Sars-CoV-2) infection confirmed by reverse transcriptase reaction followed by polymerase chain reaction (RT-PCR) were included in this prospective study. Samples were obtained weekly during the follow-up of individuals, considering symptom onset. Titers of anti-Sars-CoV-2 IgA and IgG were measured using a commercial immunoassay. Correlations between IgA/IgG and cycle threshold (Ct) values for N1 and N2 target genes were also assessed. Results: We studied 55 Covid-19 patients (59.7±16.2 years, 63.6% male), of which 28 (50.9%) died. We observed IgA and IgG positivity (IgA+ and IgG+) in 90.9% and 80% of patients, respectively. The highest IgA+ frequency was observed at weeks 2 and 3 and the highest IgG+ at weeks 3 and 4. It is important to note that patients who died presented lower IgA titers in the first two weeks (p < 0.05); however, a significant increase in IgA levels was observed in the subsequent weeks. Lastly, we identified that significant correlations between Ct values and immunoglobulins levels, both IgA and IgG were correlated with Ct N2 in patients who died. Conclusion: Our results suggest that lower IgA titers in early Covid-19, which is associated with lower Ct values, may indicate patients at higher risk for death.
{"title":"Timeline analysis of IgA and IgG levels in Covid-19 hospitalized patients according to the clinical outcome","authors":"Thalia Medeiros, F. R. Carvalho, R. Faustino, G. M. C. Guimarães, L. S. Alves, Any Caroline Oliveira, E. Azeredo, J. R. Almeida, L. Pinto, A. A. Silva","doi":"10.5935/1676-2444.20210021","DOIUrl":"https://doi.org/10.5935/1676-2444.20210021","url":null,"abstract":"ABSTRACT Introduction: Studies suggest the association between antibody production and the severity of coronavirus disease 2019 (Covid-19). Objectives: To evaluate the concentrations of immunoglobulins class A (IgA) and class G (IgG) during the hospitalization period of Covid-19 patients according to the outcome (survival vs death). Materials and methods: Patients with severe acute respiratory syndrome of coronavirus 2 (Sars-CoV-2) infection confirmed by reverse transcriptase reaction followed by polymerase chain reaction (RT-PCR) were included in this prospective study. Samples were obtained weekly during the follow-up of individuals, considering symptom onset. Titers of anti-Sars-CoV-2 IgA and IgG were measured using a commercial immunoassay. Correlations between IgA/IgG and cycle threshold (Ct) values for N1 and N2 target genes were also assessed. Results: We studied 55 Covid-19 patients (59.7±16.2 years, 63.6% male), of which 28 (50.9%) died. We observed IgA and IgG positivity (IgA+ and IgG+) in 90.9% and 80% of patients, respectively. The highest IgA+ frequency was observed at weeks 2 and 3 and the highest IgG+ at weeks 3 and 4. It is important to note that patients who died presented lower IgA titers in the first two weeks (p < 0.05); however, a significant increase in IgA levels was observed in the subsequent weeks. Lastly, we identified that significant correlations between Ct values and immunoglobulins levels, both IgA and IgG were correlated with Ct N2 in patients who died. Conclusion: Our results suggest that lower IgA titers in early Covid-19, which is associated with lower Ct values, may indicate patients at higher risk for death.","PeriodicalId":35397,"journal":{"name":"Jornal Brasileiro de Patologia e Medicina Laboratorial","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71118533","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.5935/1676-2444.20210038
J. Merlin, Andrea N. M. Amaral, L. Claro, T. Moraes, Cyntia L. Erthal, Roberto Pecoits Filho
{"title":"Reticulocyte parameters for monitoring anemia in patients with chronic kidney disease on peritoneal dialysi","authors":"J. Merlin, Andrea N. M. Amaral, L. Claro, T. Moraes, Cyntia L. Erthal, Roberto Pecoits Filho","doi":"10.5935/1676-2444.20210038","DOIUrl":"https://doi.org/10.5935/1676-2444.20210038","url":null,"abstract":"","PeriodicalId":35397,"journal":{"name":"Jornal Brasileiro de Patologia e Medicina Laboratorial","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71118580","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.5935/1676-2444.20210053
D. Ferreira, S. R. Comar
{"title":"Evaluation of mixing tests and the index of circulating anticoagulant in detecting lupus anticoagulants","authors":"D. Ferreira, S. R. Comar","doi":"10.5935/1676-2444.20210053","DOIUrl":"https://doi.org/10.5935/1676-2444.20210053","url":null,"abstract":"","PeriodicalId":35397,"journal":{"name":"Jornal Brasileiro de Patologia e Medicina Laboratorial","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71118824","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.5935/1676-2444.20210035
G. França, W. R. Silva, C. K. Medeiros, Joaquim Felipe Junior, A. Germano, Hébel Galvão
{"title":"Cystadenoma in a pediatric patient: a rare salivary gland neoplasm","authors":"G. França, W. R. Silva, C. K. Medeiros, Joaquim Felipe Junior, A. Germano, Hébel Galvão","doi":"10.5935/1676-2444.20210035","DOIUrl":"https://doi.org/10.5935/1676-2444.20210035","url":null,"abstract":"","PeriodicalId":35397,"journal":{"name":"Jornal Brasileiro de Patologia e Medicina Laboratorial","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71118931","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.5935/1676-2444.20210059
Akeme Laissa N. Coutinho, Djalma G. Xavier Filho, Marcel Christian M. Tenório, M. R. Lopes, A. P. O. Tenório
{"title":"Effectiveness of novel biomarkers of acute kidney injury in critically ill patients: a systematic review","authors":"Akeme Laissa N. Coutinho, Djalma G. Xavier Filho, Marcel Christian M. Tenório, M. R. Lopes, A. P. O. Tenório","doi":"10.5935/1676-2444.20210059","DOIUrl":"https://doi.org/10.5935/1676-2444.20210059","url":null,"abstract":"","PeriodicalId":35397,"journal":{"name":"Jornal Brasileiro de Patologia e Medicina Laboratorial","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71118964","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.5935/1676-2444.20210015
Georgina Gallucci, Estefanía Massa, C. C. Funes, R. Tozzini, S. Ghersevich
{"title":"The combination of mammaglobin A and TWIST-1 increases detection of circulating tumor cells in breast cancer","authors":"Georgina Gallucci, Estefanía Massa, C. C. Funes, R. Tozzini, S. Ghersevich","doi":"10.5935/1676-2444.20210015","DOIUrl":"https://doi.org/10.5935/1676-2444.20210015","url":null,"abstract":"","PeriodicalId":35397,"journal":{"name":"Jornal Brasileiro de Patologia e Medicina Laboratorial","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71118192","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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