Infective Endocarditis is a highly morbid disease whose diagnosis is largely based on the modified Duke Criteria. These criteria are mainly developed by expert opinion due to the low incidence of the disease, the low number of randomized trials, and the limited number of me-ta-analyses, making the evidence of their recommendations relatively low with major gaps. A prompt diagnosis of IE is crucial to avoid serious complications. However, the great clinical variability and non-specific manifestations, constitute diagnostic challenges. Hematologic abnormalities, especially anemia are frequently associated with IE. However, they have not been widely explored as potential diagnostic and prognostic parameters in IE patients. In this article, we explored the common hematologic abnormalities in IE patients and the available evidence of the impact of their changes on diagnosis and risk stratification in these patients.
{"title":"A Potential Role of Hematologic Abnormalities as Prognostic Markers an Infective Endocarditis (IE)","authors":"Rizk Sh","doi":"10.23880/mjccs-16000323","DOIUrl":"https://doi.org/10.23880/mjccs-16000323","url":null,"abstract":"Infective Endocarditis is a highly morbid disease whose diagnosis is largely based on the modified Duke Criteria. These criteria are mainly developed by expert opinion due to the low incidence of the disease, the low number of randomized trials, and the limited number of me-ta-analyses, making the evidence of their recommendations relatively low with major gaps. A prompt diagnosis of IE is crucial to avoid serious complications. However, the great clinical variability and non-specific manifestations, constitute diagnostic challenges. Hematologic abnormalities, especially anemia are frequently associated with IE. However, they have not been widely explored as potential diagnostic and prognostic parameters in IE patients. In this article, we explored the common hematologic abnormalities in IE patients and the available evidence of the impact of their changes on diagnosis and risk stratification in these patients.","PeriodicalId":356296,"journal":{"name":"Medical Journal of Clinical Trials & Case Studies","volume":"111 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133433162","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Purpose: Rib fractures are common in patients presenting chest trauma and are associated with significant morbidity and mortality. Traditional pain management options for rib fractures include thoracic epidural and/or paravertebral blocks. However, novel regional anesthesia techniques have been demonstrated to improve pain scores and aid patient recovery. We describe the application of a combined Serratus-Intercostal Fascial (SIFB) and Rectus Sheath (RS) nerve blocks to provide analgesia for a patient with lower anterior and lateral rib fractures. Clinical Features: To perform the combined block, an 18-gauge Tuohy needle was inserted deep to the rectus sheath muscle above the transversus muscle with obvious spread of local anesthetic superficial to the posterior rectus sheath where 10mls of 0.375% bupivacaine was injected. The needle continued laterally under the external oblique until it was positioned deep to the left serratus anterior muscle where an additional 15ml was injected. In both blocks, CPNB catheters were inserted beyond the end of the Tuohy needles. On postoperative day 2, the patient reported no pain in his anterior chest and abdomen with improved inspiratory capacity and was able to ambulate. After postoperative day 7 the patient no longer required his oral scheduled opioids and continued to report no chest pain. Conclusion: A combined SIFB and RS block using a single-incision was effective in providing analgesia while being less invasive and providing more control over potential infection sites. The technique also allows for lower dosage of anesthetics which can be relevant in other clinical settings.
{"title":"Combined Serratus Intercostal Fascial Block (SIFB) and Rectus Sheath Block (RSB) for Chest Wall Fracture","authors":"Chandrashekar A","doi":"10.23880/mjccs-16000322","DOIUrl":"https://doi.org/10.23880/mjccs-16000322","url":null,"abstract":"Purpose: Rib fractures are common in patients presenting chest trauma and are associated with significant morbidity and mortality. Traditional pain management options for rib fractures include thoracic epidural and/or paravertebral blocks. However, novel regional anesthesia techniques have been demonstrated to improve pain scores and aid patient recovery. We describe the application of a combined Serratus-Intercostal Fascial (SIFB) and Rectus Sheath (RS) nerve blocks to provide analgesia for a patient with lower anterior and lateral rib fractures. Clinical Features: To perform the combined block, an 18-gauge Tuohy needle was inserted deep to the rectus sheath muscle above the transversus muscle with obvious spread of local anesthetic superficial to the posterior rectus sheath where 10mls of 0.375% bupivacaine was injected. The needle continued laterally under the external oblique until it was positioned deep to the left serratus anterior muscle where an additional 15ml was injected. In both blocks, CPNB catheters were inserted beyond the end of the Tuohy needles. On postoperative day 2, the patient reported no pain in his anterior chest and abdomen with improved inspiratory capacity and was able to ambulate. After postoperative day 7 the patient no longer required his oral scheduled opioids and continued to report no chest pain. Conclusion: A combined SIFB and RS block using a single-incision was effective in providing analgesia while being less invasive and providing more control over potential infection sites. The technique also allows for lower dosage of anesthetics which can be relevant in other clinical settings.","PeriodicalId":356296,"journal":{"name":"Medical Journal of Clinical Trials & Case Studies","volume":"16 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128027964","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"C Reactive and Procalcitonin Correlation with WBC Counts in Culture Positive Patients of Sepsis","authors":"R. Sareen","doi":"10.23880/mjccs-16000225","DOIUrl":"https://doi.org/10.23880/mjccs-16000225","url":null,"abstract":"","PeriodicalId":356296,"journal":{"name":"Medical Journal of Clinical Trials & Case Studies","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131379840","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Efficacy of Nasal Smear Eosinophil Count in Detecting Allergic Rhinitis in Children","authors":"Mesbah Uddin Ahmed","doi":"10.23880/mjccs-16000309","DOIUrl":"https://doi.org/10.23880/mjccs-16000309","url":null,"abstract":"","PeriodicalId":356296,"journal":{"name":"Medical Journal of Clinical Trials & Case Studies","volume":"44 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121596697","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Knowledge, Attitude and Practices of Radiology Residents of Tertiary Government Hospitals of Peshawar Regarding Biological Hazards Caused by X-Rays","authors":"Ghazala Wahid","doi":"10.23880/mjccs-16000318","DOIUrl":"https://doi.org/10.23880/mjccs-16000318","url":null,"abstract":"","PeriodicalId":356296,"journal":{"name":"Medical Journal of Clinical Trials & Case Studies","volume":"50 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125175795","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Gastric Cancer During Pregnancy; Torsion of Krukenberg Tumor (KT)","authors":"E. Köle","doi":"10.23880/mjccs-16000224","DOIUrl":"https://doi.org/10.23880/mjccs-16000224","url":null,"abstract":"","PeriodicalId":356296,"journal":{"name":"Medical Journal of Clinical Trials & Case Studies","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127388171","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.23880/mjccs-16000s1-010
Y. Bian
{"title":"Reporting Quality Assessment of COVID-19 Clinical Trials in China at the beginning of the Pandemic: An Empirical Study based on the CONSORT Statement","authors":"Y. Bian","doi":"10.23880/mjccs-16000s1-010","DOIUrl":"https://doi.org/10.23880/mjccs-16000s1-010","url":null,"abstract":"","PeriodicalId":356296,"journal":{"name":"Medical Journal of Clinical Trials & Case Studies","volume":"2 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126130129","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.23880/mjccs-16000s1-0001
G. Dhar
{"title":"Avocado Consumption and Immune Response: A Review on Ethiopian Context","authors":"G. Dhar","doi":"10.23880/mjccs-16000s1-0001","DOIUrl":"https://doi.org/10.23880/mjccs-16000s1-0001","url":null,"abstract":"","PeriodicalId":356296,"journal":{"name":"Medical Journal of Clinical Trials & Case Studies","volume":"26 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122345966","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Advanced Heart Block in a Young Adult: CMR is Savior","authors":"K. Vora","doi":"10.23880/mjccs-16000286","DOIUrl":"https://doi.org/10.23880/mjccs-16000286","url":null,"abstract":"","PeriodicalId":356296,"journal":{"name":"Medical Journal of Clinical Trials & Case Studies","volume":"214 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122375227","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Medication-Induced Variations on Electrocardiographic Patterns: A Contrast between Atypical Antipsychotics","authors":"Saeed Shoja Shafti","doi":"10.23880/mjccs-16000240","DOIUrl":"https://doi.org/10.23880/mjccs-16000240","url":null,"abstract":"","PeriodicalId":356296,"journal":{"name":"Medical Journal of Clinical Trials & Case Studies","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126024003","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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