Pub Date : 1900-01-01DOI: 10.5336/intermed.2022-90367
Münevver Nazlıcan Zengi̇n, Y. Şahin, H. Yüce, O. Çiftçi
{"title":"Molecular Diagnostic Tests and Pharmacological Therapy Approaches in Celiac Disease: A Systematic Review","authors":"Münevver Nazlıcan Zengi̇n, Y. Şahin, H. Yüce, O. Çiftçi","doi":"10.5336/intermed.2022-90367","DOIUrl":"https://doi.org/10.5336/intermed.2022-90367","url":null,"abstract":"","PeriodicalId":357154,"journal":{"name":"Turkiye Klinikleri Journal of Internal Medicine","volume":"75 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126963584","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.5336/intermed.2021-85714
M. E. Kardan, Enes Ardic, S. Akpınar, Birol Safak, Mustafa Doğan, H. Sasani, N. Kiraz, B. Turgut, I. Erdem
{"title":"A Case of Invasive Pulmonary Aspergillosis in a Patient with Acute Lymphoblastic Leukemia Caused by Aspergillus Flavus","authors":"M. E. Kardan, Enes Ardic, S. Akpınar, Birol Safak, Mustafa Doğan, H. Sasani, N. Kiraz, B. Turgut, I. Erdem","doi":"10.5336/intermed.2021-85714","DOIUrl":"https://doi.org/10.5336/intermed.2021-85714","url":null,"abstract":"","PeriodicalId":357154,"journal":{"name":"Turkiye Klinikleri Journal of Internal Medicine","volume":"23 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126969813","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.5336/intermed.2021-85192
Özlem Çakır Madenci, Müjgan Kaya Tuna, Özlem Hürmeydan, A. Orçun
{"title":"Effect of Body Weight Reduction on Serum Irisin Levels: Experimental Study","authors":"Özlem Çakır Madenci, Müjgan Kaya Tuna, Özlem Hürmeydan, A. Orçun","doi":"10.5336/intermed.2021-85192","DOIUrl":"https://doi.org/10.5336/intermed.2021-85192","url":null,"abstract":"","PeriodicalId":357154,"journal":{"name":"Turkiye Klinikleri Journal of Internal Medicine","volume":"22 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126468290","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.5336/intermed.2021-81042
B. Çavuş, Aslı Çiftçibaşi Örmeci, R. Iliaz, A. Atasoy, G. Yegen, Özge Tepe, Ç. Karaca, K. Demir, S. Beşişik, S. Kaymakoğlu, F. Akyüz
{"title":"Evaluation of Histopathological Correspondence of Atrophic Gastritis Observed in Endoscopy: Systematic Review","authors":"B. Çavuş, Aslı Çiftçibaşi Örmeci, R. Iliaz, A. Atasoy, G. Yegen, Özge Tepe, Ç. Karaca, K. Demir, S. Beşişik, S. Kaymakoğlu, F. Akyüz","doi":"10.5336/intermed.2021-81042","DOIUrl":"https://doi.org/10.5336/intermed.2021-81042","url":null,"abstract":"","PeriodicalId":357154,"journal":{"name":"Turkiye Klinikleri Journal of Internal Medicine","volume":"102 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115643003","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.5336/intermed.2019-72400
B. Kara
94 Cinsiyet hormonlarının, kadın ve erkeklerde cinsiyete ait özelliklerin gelişmesini ve üreme organlarının yapı ve fonksiyonlarını etkilediği bilinmektedir. Bununla birlikte son çalışmalar, vücudumuzda neredeyse bütün doku ve organların (beyin, kemikler, karaciğer ve böbrekler gibi) yapı ve fonksiyonlarında cinsiyet hormonlarının oldukça önemli etkileri olduğunu ortaya koymaktadır. Cinsiyet hormonlarının organizmada üreme, farklılaşma, büyüme, gelişme ve homeostaz gibi fonksiyonlarda rolleri bulunmaktadır. Bu durum ise cinsiyet farklılıklarının gelişmesine neden olmaktadır.1,2
{"title":"What is the Effect of Gender on Kidney Structure and Functions?","authors":"B. Kara","doi":"10.5336/intermed.2019-72400","DOIUrl":"https://doi.org/10.5336/intermed.2019-72400","url":null,"abstract":"94 Cinsiyet hormonlarının, kadın ve erkeklerde cinsiyete ait özelliklerin gelişmesini ve üreme organlarının yapı ve fonksiyonlarını etkilediği bilinmektedir. Bununla birlikte son çalışmalar, vücudumuzda neredeyse bütün doku ve organların (beyin, kemikler, karaciğer ve böbrekler gibi) yapı ve fonksiyonlarında cinsiyet hormonlarının oldukça önemli etkileri olduğunu ortaya koymaktadır. Cinsiyet hormonlarının organizmada üreme, farklılaşma, büyüme, gelişme ve homeostaz gibi fonksiyonlarda rolleri bulunmaktadır. Bu durum ise cinsiyet farklılıklarının gelişmesine neden olmaktadır.1,2","PeriodicalId":357154,"journal":{"name":"Turkiye Klinikleri Journal of Internal Medicine","volume":"54 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114687779","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.5336/intermed.2022-88130
Mehmet Şimşek, M. Güven, D. Geneş, H. Saraçoğlu, Z. Pekkolay, A. Tuzcu, M. Akil
ABS TRACT Objective: Although it is known that cardiac dysfunction may develop due to long-term use of cabergoline at high doses, there is not enough information in the literature on low-dose use. In this study, we aimed to investigate the relationship between low-dose long-term use of cabergoline due to functional pituitary adenoma and heart valve dysfunction. Material and Methods: Patients using low-dose (0.5-1 mg/week) cabergoline for at least one year due to functional pi- tuitary adenoma (prolactinoma and acromegaly) were included in our study. Group 1A (n=50) with a diagnosis of prolactinoma who received cabergoline, Group 1B (n=47) of the healthy control group who did not receive it; Group 2A (n=29) diagnosed with acromegaly and receiving cabergoline was named as Group 2B (n=22) not receiving it. Subjects were evaluated by transthoracic echocardiography for heart valve fail- ure. Results: The incidence of mild heart valve failure was higher in Group 1A and Group 2A patients using cabergoline, while moderate and severe heart valve failure was not observed at all. The median cumulative dose of cabergoline was 169 mg [interquartile range (IQR), 104-377 mg] in Group 1A, compared to a median 310 mg (IQR, 208-572 mg) in Group 2A (p=0.009). In the Cox proportional hazard re- gression analysis created to predict heart valve failure, cumulative cabergoline dose was observed as the effective factor in univariant and multivariate analyzes [hazard ratio: 0.99 (95% confidence interval, 0.995-0.999), p<0.001; hazard ratio: 0.99 (95% confidence interval, 0.995-0.999), p=0.001]. Conclusion: Long-term use of low-dose cabergoline in pituitary adenomas may be associated with mild heart valvu- lar insufficiency.
{"title":"The Relationship Between Long-Term Low-Dose Use of Cabergoline and Heart Valve Dysfunction in Pituitary Adenomas: A Retrospective Observational Study","authors":"Mehmet Şimşek, M. Güven, D. Geneş, H. Saraçoğlu, Z. Pekkolay, A. Tuzcu, M. Akil","doi":"10.5336/intermed.2022-88130","DOIUrl":"https://doi.org/10.5336/intermed.2022-88130","url":null,"abstract":"ABS TRACT Objective: Although it is known that cardiac dysfunction may develop due to long-term use of cabergoline at high doses, there is not enough information in the literature on low-dose use. In this study, we aimed to investigate the relationship between low-dose long-term use of cabergoline due to functional pituitary adenoma and heart valve dysfunction. Material and Methods: Patients using low-dose (0.5-1 mg/week) cabergoline for at least one year due to functional pi- tuitary adenoma (prolactinoma and acromegaly) were included in our study. Group 1A (n=50) with a diagnosis of prolactinoma who received cabergoline, Group 1B (n=47) of the healthy control group who did not receive it; Group 2A (n=29) diagnosed with acromegaly and receiving cabergoline was named as Group 2B (n=22) not receiving it. Subjects were evaluated by transthoracic echocardiography for heart valve fail- ure. Results: The incidence of mild heart valve failure was higher in Group 1A and Group 2A patients using cabergoline, while moderate and severe heart valve failure was not observed at all. The median cumulative dose of cabergoline was 169 mg [interquartile range (IQR), 104-377 mg] in Group 1A, compared to a median 310 mg (IQR, 208-572 mg) in Group 2A (p=0.009). In the Cox proportional hazard re- gression analysis created to predict heart valve failure, cumulative cabergoline dose was observed as the effective factor in univariant and multivariate analyzes [hazard ratio: 0.99 (95% confidence interval, 0.995-0.999), p<0.001; hazard ratio: 0.99 (95% confidence interval, 0.995-0.999), p=0.001]. Conclusion: Long-term use of low-dose cabergoline in pituitary adenomas may be associated with mild heart valvu- lar insufficiency.","PeriodicalId":357154,"journal":{"name":"Turkiye Klinikleri Journal of Internal Medicine","volume":"8 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125455699","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.5336/intermed.2019-72064
M. Kaplan, S. Dışıbeyaz, V. Gökbulut
88 Gangliositik paraganglioma (GP), nadir görülen bir gastroenteropankreatik nöroendokrin tümördür.1 Çoğunlukla asemptomatiktir, ancak hastalar nadiren ileus, kanama gibi komplikasyonlarla başvurabilirler.2,3 Başlıca tedavi seçeneği ise cerrahi olarak tümörün çıkartılmasıdır.4 Bu hastalarda cerrahi rezeksiyon yüksek morbidite, uzun hastanede kalış süresi ve bazen mortalite ile ilişkilidir. Bu nedenle son zamanlarda, bu lezyonların endoskopik olarak çıkartılması önerilmektedir.5 Biz de kilo kaybı ve dispeptik yakınmalar ile başvurup endoskopide papil lokalizasyonunda kitle tespit edilen ve akabinde endoskopik ampullektomi ile hem tanı konulan hem de tedavi edilen bir GP vakasını sunuyoruz. OLGU SUNUMU
{"title":"Treatment of Duodenal Gangliocytic Paraganglioma with Endoscopic Ampullectomy","authors":"M. Kaplan, S. Dışıbeyaz, V. Gökbulut","doi":"10.5336/intermed.2019-72064","DOIUrl":"https://doi.org/10.5336/intermed.2019-72064","url":null,"abstract":"88 Gangliositik paraganglioma (GP), nadir görülen bir gastroenteropankreatik nöroendokrin tümördür.1 Çoğunlukla asemptomatiktir, ancak hastalar nadiren ileus, kanama gibi komplikasyonlarla başvurabilirler.2,3 Başlıca tedavi seçeneği ise cerrahi olarak tümörün çıkartılmasıdır.4 Bu hastalarda cerrahi rezeksiyon yüksek morbidite, uzun hastanede kalış süresi ve bazen mortalite ile ilişkilidir. Bu nedenle son zamanlarda, bu lezyonların endoskopik olarak çıkartılması önerilmektedir.5 Biz de kilo kaybı ve dispeptik yakınmalar ile başvurup endoskopide papil lokalizasyonunda kitle tespit edilen ve akabinde endoskopik ampullektomi ile hem tanı konulan hem de tedavi edilen bir GP vakasını sunuyoruz. OLGU SUNUMU","PeriodicalId":357154,"journal":{"name":"Turkiye Klinikleri Journal of Internal Medicine","volume":"25 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114417367","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.5336/intermed.2022-92907
R. Büberci, S. Karahisar Şirali, M. Duranay
{"title":"The Effects of Socio-Economic Status and Medical Treatments on Mortality in Long Term Peritonal Dialysis Patients: Retrospective Cross-Sectional Research","authors":"R. Büberci, S. Karahisar Şirali, M. Duranay","doi":"10.5336/intermed.2022-92907","DOIUrl":"https://doi.org/10.5336/intermed.2022-92907","url":null,"abstract":"","PeriodicalId":357154,"journal":{"name":"Turkiye Klinikleri Journal of Internal Medicine","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126115222","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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