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The Dimensional Changes of Clasp Arm in Removable Partial Denture Frameworks Fabricated Through DMLS and Conventional Lost Wax Technique: An In Vitro Study 通过 DMLS 和传统失蜡技术制作的可摘局部义齿框架中扣臂的尺寸变化:体外研究
Q4 Agricultural and Biological Sciences Pub Date : 2023-12-14 DOI: 10.17762/jaz.v44is7.2744
K. L. Sai, Suresh Venugopalan
AIM: The aim of the present study is to evaluate the effect of CAD designing on the dimensions of the clasp arm. METHODOLOGY: A Kennedy Class III mod I cast was selected as the reference cast. Samples were divided into 2 groups, Group I with DMLS and Group II with Conventional lost wax technique. Three reference points were selected on the clasp arm and the vertical dimensions were measured in the digital design and compared it with the dimensions at the same points in the final framework. RESULTS: There was slight expansion in group 1 (p-value > 0.05) with mean of -0.035 and standard deviation 0.088. And there was decrease in dimensions in the clasp arm in group 2 (p-value < 0.05) with mean of 0.1741 and standard deviation 0.081. CONCLUSION: From the present study, it was concluded that the dimensions of the clasp arm of DMLS framework increased slightly, whereas the there was significant decrease in the clasp arm dimensions in the framework produced through conventional lost wax technique. Both the frameworks had clinically acceptable fit.
目的:本研究旨在评估 CAD 设计对扣臂尺寸的影响。方法:选择肯尼迪 III 类 I 型铸件作为参考铸件。样品分为两组,第一组采用 DMLS 技术,第二组采用传统失蜡技术。在扣臂上选择三个参考点,测量数字设计中的垂直尺寸,并与最终框架中相同点的尺寸进行比较。结果:第一组有轻微膨胀(p 值大于 0.05),平均值为-0.035,标准差为 0.088。而第 2 组的扣臂尺寸有所减小(p 值小于 0.05),平均值为 0.1741,标准差为 0.081。结论:本研究得出的结论是,DMLS 框架的扣臂尺寸略有增加,而通过传统失蜡技术制作的框架的扣臂尺寸显著减少。两种框架在临床上都具有可接受的密合度。
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引用次数: 0
Effect of Flavonoids in Preventing Breast Cancer: A Review 类黄酮在预防乳腺癌方面的作用:综述
Q4 Agricultural and Biological Sciences Pub Date : 2023-12-14 DOI: 10.17762/jaz.v44is6.2799
Disha Paul, Sampurna Chakraborty, Souvik Tewari, Jayashree Das
Epidemiological research has found a wide range of environmental and dietary risk factors for different cancers nowadays. The four most prevalent cancers— breast, colorectal, lung, and prostate—have all been linked to lifestyle factors in affluent nations. Flavonoids are a significant group of phenolic plant compounds made up of derivatives of 2-phenyl-benzopyrone. Flavonoids, foods such as fruits, vegetables, cereals, bark, roots, stems, flowers, tea, and wine include a group of chemical compounds with different phenolic structures. There are currently efforts being made to separate the purported flavonoids from the other components because these natural chemicals have numerous beneficial health effects. The various sources of flavonoids, their subclasses, and how they aid in the prevention of breast cancer will be outlined in this review article.
流行病学研究发现,当今不同癌症的环境和饮食风险因素多种多样。最常见的四种癌症--乳腺癌、结肠直肠癌、肺癌和前列腺癌--都与富裕国家的生活方式有关。类黄酮是一类重要的酚类植物化合物,由 2-苯基-苯并吡喃酮的衍生物组成。类黄酮、水果、蔬菜、谷物、树皮、根、茎、花、茶和酒等食物包括一组具有不同酚类结构的化合物。目前,人们正在努力将所谓的类黄酮从其他成分中分离出来,因为这些天然化学物质具有许多有益健康的功效。本综述文章将概述类黄酮的各种来源、亚类以及它们如何帮助预防乳腺癌。
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引用次数: 0
Phytochemical Analysis (LC-MS) of Azadirachta Indica Ethanolic Extract, Antioxidant, Anticancer, in Vitro Wound Healing Activity, and Immunomodulatory Effects of Azadirachta Indica Ethanolic Extract 印度杜鹃乙醇提取物的植物化学分析(LC-MS)、抗氧化、抗癌、体外伤口愈合活性和免疫调节作用
Q4 Agricultural and Biological Sciences Pub Date : 2023-12-14 DOI: 10.17762/jaz.v44is7.2727
Loganathan Thavamani, Palanisamy Selvaraj, Muarali R, Natesan Vijayakumar, Aruna Periyasamy, Muddukrishnaiah Kotakonda, Sirajudheen Mukriyan Kallungal
This study presents a comprehensive investigation of the medicinal attributes of the ethanolic extract obtained from Azadirachta indica (A. indica) leaves collected from the Jamia Salafiya Pharmacy College campus in Malappuram District, Kerala, South India. The plant was meticulously identified by Dr. Samuel Thavamni B, a plant pharmacognosy specialist. The ethanolic extraction process was performed using the Soxhlet method. Phytochemical analysis was performed using liquid chromatography-LC-MS (liquid chromatography-mass and Mass spectroscopy). The in vitro antioxidant, MTT ((3-(4,5-Dimethylthiazol-2-yl)-2,5-Diphenyltetrazolium Bromide) assay, Apoptosis, and Immunomodulatory activity of ethanolic A. indica were evaluated. The extraction resulted in a semi-solid, dark-coloured extract with a yield of 8.67%. Phytochemical analysis using LC-MS identified key constituents such as octadecanoic acid, tetradecanoic acid, caryophyllene, 1,4-Eicosadiene, and triacontanoic acid, methyl ester, known for anti-inflammatory, antioxidant, and antimicrobial properties. In vitro antioxidant assays revealed a concentration-dependent inhibitory effect, with the A. indica ethanolic extract demonstrating substantial antioxidant capacity (77.81% at 100 µg), comparable to that of ascorbic acid (97.22%). However, the MTT assay indicated a concentration-dependent decrease in cell viability, emphasizing the need for caution owing to potential cytotoxic effects. Acridine orange/ethidium bromide staining provided insights into the induction of apoptosis in MCF-7 cells, highlighting the beneficial effects of the extract on cellular morphology. The scratch wound healing assay suggested the potential of the extract to promote fibroblast migration, implicating its role in enhancing wound healing. Immunomodulatory activity assessment revealed concentration-dependent modulation of immune responses, with the extract demonstrating a notable immunomodulatory effect of 77.81% at 100 µg. These findings shed light on the medicinal potential of A. indica, emphasizing the need for further research to elucidate the underlying mechanisms. The diverse chemical composition and multifaceted effects of the extract, from antioxidant and cytotoxic activities to immunomodulation and wound healing promotion, underscore its significance in pharmaceuticals and herbal remedies.
本研究全面调查了从印度南部喀拉拉邦马拉普拉姆地区的贾米亚-萨拉菲亚药学院校园采集的 Azadirachta indica(A. indica)叶片乙醇提取物的药用特性。植物药理专家 Samuel Thavamni B 博士对该植物进行了细致的鉴定。乙醇提取过程采用索氏提取法。植物化学分析采用液相色谱-液相色谱-质谱法进行。评估了乙醇 A. indica 的体外抗氧化、MTT(3-(4,5-二甲基噻唑-2-基)-2,5-二苯基溴化四氮唑)测定、细胞凋亡和免疫调节活性。萃取结果为半固体深色提取物,产率为 8.67%。利用 LC-MS 进行的植物化学分析确定了十八酸、十四酸、叶黄素、1,4-二十二烯和三蚁酸甲酯等主要成分,这些成分具有抗炎、抗氧化和抗菌特性。体外抗氧化试验显示了一种浓度依赖性抑制作用,A. indica 乙醇提取物显示出很强的抗氧化能力(100 µg 时为 77.81%),与抗坏血酸的抗氧化能力(97.22%)相当。不过,MTT 试验表明,细胞活力的降低与浓度有关,因此需要谨慎对待潜在的细胞毒性效应。吖啶橙/溴化乙锭染色法揭示了 MCF-7 细胞凋亡的诱导过程,凸显了提取物对细胞形态的有益影响。划痕伤口愈合试验表明,萃取物具有促进成纤维细胞迁移的潜力,这也暗示了它在促进伤口愈合方面的作用。免疫调节活性评估显示了免疫反应的浓度依赖性调节作用,提取物在 100 µg 时的免疫调节效果为 77.81%。这些发现揭示了籼稻的药用潜力,强调了进一步研究阐明其潜在机制的必要性。从抗氧化和细胞毒性活性到免疫调节和促进伤口愈合,该提取物具有多种化学成分和多方面的功效,这凸显了它在制药和草药疗法中的重要意义。
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引用次数: 0
To Study the Students Behaviour on Use of Mobile Wallets 研究学生使用手机钱包的行为
Q4 Agricultural and Biological Sciences Pub Date : 2023-12-14 DOI: 10.17762/jaz.v44is7.2724
Gulabchand K Gupta, Ravikumar Gupta
In the present scenario, Mobile phones are used everywhere. The digital wallet or Electronic wallets has made everything possible just one bit. The Mobile Wallet Applications have made users to pay any bills, college fees and manage their money transaction to any place at their convenience. The cash money in the digital format is a generally Mobile wallet Applications linked with credit card or debit card or online banking system. There are various Application of Mobile Wallets such as Google Pay, Paytm, PhonePe, Freecharge, BHIM, AmazonPay and so on.  This paper will give the student’s points of view on use of Mobile Wallets and other methods of payments, college fees and other purchases.
在当前形势下,手机的使用无处不在。数字钱包或电子钱包让一切变得可能。移动钱包应用程序使用户可以在任何地方方便地支付任何账单、大学费用和管理他们的资金交易。数字格式的现金一般是与信用卡、借记卡或网上银行系统相连接的移动钱包应用程序。移动钱包的应用多种多样,如 Google Pay、Paytm、PhonePe、Freecharge、BHIM、AmazonPay 等。 本文将介绍学生对使用手机钱包和其他支付方式、大学学费和其他消费的看法。
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引用次数: 0
Kinetic Characterization and Partial Purification of Peroxidase in Eucalyptus F1 Hybrids 桉树 F1 代杂交种过氧化物酶的动力学特征和部分纯化
Q4 Agricultural and Biological Sciences Pub Date : 2023-12-14 DOI: 10.17762/jaz.v44is7.2761
V. Jadon, Barkha Kamal, Geeta Bhandari, Nupur Joshi, Archna Dhasmana, Sanjay Gupta
A differential pattern of peroxidase (E.C. 1.1.11.7) has been observed in reciprocal F1 hybrids of Eucalyptus (FRI-4 and FRI-5) produced using parental combination of E. tereticornis and E. camaldulensis. The hybrids were characterized for the qualitative, kinetic parameters (total and specific activity, units, Km and Vmax) and partial purification of peroxidase. The qualitative study showed the presence of high molecular weight peroxidase isoforms i.e. 260 KD, 250 KD and 110KD bands. A strong maternal inheritance was observed for 260 KD loci in FRI-5. Kinetic characterization of peroxidase revealed that F1 genotypes had efficient peroxidase system over their parental combination resulting in 8 -10 times more heterotic vigour. The FRI-5 genotypes were found to be having efficient peroxidase system with lowest Km values (0.12mM-0.17mM) and higher Vmax values ranging from 0.07-0.14mM min-1mg prot-1. The study revealed the role of maternal inheritance and was found that better genotypes are produced when superior parents are used as seed parent. The results suggest the efficient use of peroxidase marker for the identification of the better genotypes in forest tree species.  
在使用 E. tereticornis 和 E. camaldulensis 的亲本组合生产的桉树互交 F1 杂交种(FRI-4 和 FRI-5)中,观察到过氧化物酶(E.C. 1.1.11.7)的不同模式。对杂交种进行了过氧化物酶的定性、动力学参数(总活性和特定活性、单位、Km 和 Vmax)和部分纯化。定性研究显示存在高分子量过氧化物酶同工型,即 260 KD、250 KD 和 110KD 带。在 FRI-5 中,观察到 260 KD 位点具有很强的母系遗传性。过氧化物酶的动力学特征显示,F1 基因型的过氧化物酶系统比亲本组合更有效,从而使杂交活力提高了 8-10 倍。发现 FRI-5 基因型具有高效的过氧化物酶系统,其 Km 值最低(0.12mM-0.17mM),Vmax 值较高,为 0.07-0.14mM min-1mg prot-1。该研究揭示了母系遗传的作用,并发现当使用优良亲本作为种子亲本时,能培育出更好的基因型。研究结果表明,利用过氧化物酶标记物可以有效鉴定林木物种的优良基因型。
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引用次数: 0
Antiemetics Commonly Prescribed in Children Undergoing Dental Treatment Under General Anaesthesia- A Retrospective Cohort Study 在全身麻醉下接受牙科治疗的儿童常用止吐药--一项回顾性队列研究
Q4 Agricultural and Biological Sciences Pub Date : 2023-12-14 DOI: 10.17762/jaz.v44is7.2749
Amrithaa.B Amrithaa.B, Dr. Lavanya Govindaraju
Background: Postoperative nausea and vomiting (PONV) are the most widely recognized unfavorable impact of pediatric anaesthesia and medical procedure Numerous antiemetic drugs are utilized for preventive treatment. They have different biochemical collaborations and inconveniences, yet there is still a weakness about which drugs are best with the least side effects. Aim: The aim of the current study is to find the antiemetics commonly prescribed in children undergoing dental procedures in general anaesthesia. Materials and Methods: The retrospective study was led in a private dental school, Chennai, India. Moral endorsement was obtained from the Institutional audit board before the beginning of the review. Information was gathered from DIAS (Dental Information Archiving Software) and the board framework records of the children under 18 years old who were treated under broad anaesthesia between September 2020 and February 2021 which was placed in the systemic way. A comfort test of 100 children going through dental treatment under general anaesthesia who were endorsed with antiemetics were remembered for the review. Information gathered with following boundaries like age, gender, antiemetics given. The classification of information was done in excel sheets and imported to SPSS. Results: Among 100 children treated under general anaesthesia, 56 were males and 44 were females. As a total count male were higher with a percentage of 56% when compared to females with 44%. 65% of ondansetron and 35% of metoclopramide antiemetic drugs were commonly prescribed in children undergoing dental treatment in general anaesthesia. Conclusion: There is high-certainty evidence that ondansetron drugs decrease vomiting, and moderate - assurance evidence that metoclopramide drugs probably reduce vomiting.
背景:术后恶心和呕吐(PONV)是公认的小儿麻醉和医疗过程中最不利的影响,目前有许多止吐药用于预防治疗。这些药物有不同的生化作用和不便之处,但哪种药物最好、副作用最小仍是一个难题。目的:本研究旨在找出在全身麻醉下进行牙科手术的儿童常用的止吐药。材料和方法:这项回顾性研究在印度钦奈的一所私立牙科学校进行。审查开始前已获得机构审计委员会的道德认可。研究人员从 DIAS(牙科信息存档软件)和委员会框架中收集了 2020 年 9 月至 2021 年 2 月期间接受过全身麻醉治疗的 18 岁以下儿童的信息,并将其纳入系统中。对 100 名在全身麻醉下接受牙科治疗并使用止吐药的儿童进行了舒适度测试,以进行回顾性记忆。收集的信息包括年龄、性别、使用的止吐药等。信息分类在 excel 表中完成,并导入到 SPSS 中。结果在接受全身麻醉治疗的 100 名儿童中,男性 56 人,女性 44 人。在总人数中,男性占 56%,女性占 44%。在全身麻醉下接受牙科治疗的儿童中,常用的止吐药为65%的昂丹司琼和35%的甲氧氯普胺。结论有高度确凿的证据表明,昂丹司琼可减少呕吐,有中度确凿的证据表明,甲氧氯普胺可减少呕吐。
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引用次数: 0
Comparative Analysis of Figurative Comparisons in The English and Uzbek 英语和乌兹别克语中比喻句的比较分析
Q4 Agricultural and Biological Sciences Pub Date : 2023-12-14 DOI: 10.17762/jaz.v44is1.2787
Sodiqova Sayyoraxon Talabovna, Rapiqjonov Rahmonjon Ravshanjon o’gli
Comparisons conceptualize the body of human knowledge about the world and its fragments, reflect the traits of people's mentalities, and aid in the generational transmission of national standards and stereotypes. The study of comparisons has been the subject of numerous works, but none of them addressed comparisons from a linguocultural or comparative perspective. Studying figurative comparisons between English and Uzbek from the perspective of how language and culture interact, as well as how well speakers of both languages are able to exchange cultural information and reflect social phenomena, seems pertinent. It is important to remember that English and Uzbek comparisons do not always have the same foundation.
比较概念化了人类关于世界及其碎片的知识体系,反映了人们的心理特征,有助于国家标准和陈规陋习的代代相传。关于比较的研究成果不胜枚举,但没有一部是从语言文化或比较的角度来研究比较的。从语言和文化如何互动以及两种语言的使用者如何交流文化信息和反映社会现象的角度来研究英语和乌兹别克语之间的形象比较似乎很有意义。重要的是要记住,英语和乌兹别克语的比较并不总是具有相同的基础。
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引用次数: 0
Sensory Evaluation of Antioxidant Enriched and Iron Based Prebiotic Milk Cake 富含抗氧化剂和铁的益生菌奶糕的感官评估
Q4 Agricultural and Biological Sciences Pub Date : 2023-12-14 DOI: 10.17762/jaz.v44is7.2751
Moumita Das, Madhumita Mondal, Poulami Adhikary Mukherjee, Rita Mondal, Pragya Tiwari, Ranajit Kumar Khalua
The main objective of this research study was to develop antioxidant enriched and iron based prebiotic milk cake and to evaluate sensory analysis of newly prepared milk cake. In this research study, control milk cake was developed without prebiotics and experimental milk cake was prepared by different percentage of prebiotics. As a prebiotics kiwi fruits powder was used. The nutritional value of bakery goods and their potential for use in feeding programmes and emergencies captured the attention of customers. After sensory analysis, it was found that T3 treatment combination was showed higher overall acceptability.
这项研究的主要目的是开发富含抗氧化剂和铁的益生元牛奶蛋糕,并对新制备的牛奶蛋糕进行感官分析评估。在这项研究中,对照组牛奶蛋糕没有添加益生元,而实验组牛奶蛋糕则添加了不同比例的益生元。实验中使用了奇异果粉作为益生元。烘焙食品的营养价值及其在喂养计划和紧急情况下的使用潜力吸引了顾客的注意。经过感官分析,发现 T3 处理组合的总体可接受性更高。
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引用次数: 0
A Cross-Sectional Study of Investigating the Errors in Prescription and Drug Prescribing Pattern among General Community 调查普通社区处方错误和药物处方模式的横断面研究
Q4 Agricultural and Biological Sciences Pub Date : 2023-12-14 DOI: 10.17762/jaz.v44is7.2757
Roopini R, Bharath Kaarthic. R, Guru Krishna. N, Sai Saravanan. M, Mothieshwaran. D, Sonia. K
The main purpose of this study is to access the awareness and knowledge of finding out errors in prescription among general public which include determination of the quality of prescription in hospital pharmacy and to address the errors identified in prescriptions. Implementation of teaching electronic medical record within didactic using drug info assignment. This survey emphasised the need for monitoring and evaluating the prescription handling conducted through google form. Therefore, the present study will help to understand the prescribing patterns and errors to the general community which will, in turn, improve the quality of the use of medicine and healthcare facilities. This following report has comprehensive studies that public have developed knowledge about prescription parts, drug information, self-evaluation, health care factors when compared to previous studies
本研究的主要目的是了解公众对发现处方错误的认识和知识,其中包括确定医院药房的处方质量,并解决处方中发现的错误。在教学中使用药物信息作业实施电子病历教学。这项调查强调了通过谷歌表格监控和评估处方处理的必要性。因此,本研究将有助于了解一般社区的处方模式和错误,进而提高药品和医疗设施的使用质量。与之前的研究相比,以下报告中的综合研究表明,公众已对处方部分、药物信息、自我评价、医疗保健因素等方面有了一定的了解
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引用次数: 0
Genetic Component and Character Association for Yield and Yield Component Traits in Bread Wheat (Triticum aestivum L.) 面包小麦(Triticum aestivum L.)产量和产量组分性状的遗传组分和特征关联
Q4 Agricultural and Biological Sciences Pub Date : 2023-12-14 DOI: 10.17762/jaz.v44is7.2767
Sumit Kumar, Y. P. Singh, Kuldeep Kumar Bhargav
The current research involves the implementation of half diallel crosses between ten genotypes of bread wheat in 2018-2019. The parents and their F1 generation, excluding reciprocals, were then cultivated in the 2019-2020 growing season at the agriculture research farm, School of Agricultural Sciences and Engineering, IFTM University, Lodhipur Rajput, Moradabad (U.P.) and R.B. (PG) College, Mudi, Agra, using a randomized complete block design with three replications. Knowledge of type of gene action controlling target traits and genetic behaviour is a basic principle for designing an appropriate breeding procedure for the purpose of genetic improvement. Hence, the success of any selection or hybridization breeding program for developing varieties depends on precise estimates of genetic variation components for traits of interest which may be additive, dominant and non-allelic interaction effects. Significant genotype means squares and its components (parents and crosses) were obtained for all traits in both locations. Genetic components analysis found that additive (D) and Dominance (H1) was significant in all the traits. The value of mean degree of dominance was greater than additive, indicating availability of over dominance for all the traits. The present investigation revealed that grain yield was positively correlated with days to maturity, plant height, number of effective tillers per plant spike length, number of spikelets per spike, days to 50% heading and yield (q ha-1). Hence, more importance should be given to these traits while exercising selection. Based on the correlation and path studies it was reported that days to ear head emergence, days to maturity, plant height, number of effective tillers per plant, number of spikelets per spike, number of grains per spike, grain yield per plant and 1000 grain weight could be used as important selection traits in order of merit to improve productivity during designing a suitable breeding programme in wheat.
目前的研究涉及 2018-2019 年实施的 10 个面包小麦基因型之间的半拨杂交。亲本及其 F1 代(不包括互交子代)随后于 2019-2020 年生长季节在莫拉达巴德(乌拉巴托)洛迪普尔拉杰普特的 IFTM 大学农业科学与工程学院农业研究农场和阿格拉穆迪的 R.B.(PG)学院进行栽培,采用三次重复的随机完全区组设计。了解控制目标性状和遗传行为的基因作用类型是为遗传改良目的设计适当育种程序的基本原则。因此,任何品种选育或杂交育种计划的成功与否都取决于对相关性状遗传变异成分的精确估计,这些遗传变异成分可能是加性、显性和非等位互作效应。两地所有性状的基因型均方差及其成分(亲本和杂交种)均显著。遗传成分分析发现,加性(D)和显性(H1)对所有性状都有显著影响。平均显性程度值大于加性,表明所有性状都存在超显性。本次调查显示,谷物产量与成熟天数、株高、每株有效分蘖数、穗长、每穗小穗数、50%穗期天数和产量(q ha-1)呈正相关。因此,在进行选择时应更加重视这些性状。根据相关性和路径研究,在设计合适的小麦育种计划时,可将出穗天数、成熟天数、株高、每株有效分蘖数、每穗小穗数、每穗粒数、每株谷物产量和千粒重作为重要的选择性状,以提高生产力。
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引用次数: 0
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Journal of Advanced Zoology
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