Structural Heart最新文献

{"title":"Uniform Safety and Excellent Performance of Pressure-Regulated Deployment of Transcatheter Aortic Valves","authors":"Afik Snir MBBS, BE , Michael K. Wilson MBBS , Bianca Coelho BSc , Andrew Moussad MBBS , Christopher Naoum MBBS, PhD , Stephen G. Worthley MBBS, PhD , Michael J. Reardon MD , David S. Celermajer MBBS, PhD , Martin K. Ng MBBS, PhD","doi":"10.1016/j.shj.2025.100708","DOIUrl":"10.1016/j.shj.2025.100708","url":null,"abstract":"","PeriodicalId":36053,"journal":{"name":"Structural Heart","volume":"9 9","pages":"Article 100708"},"PeriodicalIF":2.8,"publicationDate":"2025-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144886394","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cardiac Implantable Electronic Devices and Transcatheter Tricuspid Valve Replacement With the EVOQUE System: A Case-Review Series Highlighting Procedural and Management Considerations","authors":"Raviteja R. Guddeti MD,&nbsp;Puvi Seshiah MD,&nbsp;Richard Bae MD,&nbsp;Nadia El-Hangouche MD,&nbsp;Alex Costea MD,&nbsp;Edward Schloss MD,&nbsp;Mehmet Yildiz MD,&nbsp;Santiago Garcia MD","doi":"10.1016/j.shj.2025.100707","DOIUrl":"10.1016/j.shj.2025.100707","url":null,"abstract":"<div><div>Severe, untreated tricuspid regurgitation is associated with worse clinical outcomes. While isolated tricuspid valve (TV) surgery has been linked to poor long-term outcomes, transcatheter TV therapies, including edge-to-edge repair and transcatheter tricuspid valve replacement (TTVR), have emerged as effective alternatives and have been shown to improve outcomes, leading to their regulatory approval in the United States. Conduction system abnormalities are commonly seen among patients undergoing TTVR due to the close proximity of the atrioventricular node and the His bundle to the TV annulus. In the TRISCEND II (Transcatheter Tricuspid Valve Replacement: Pivotal Clinical Investigation of Safety and Clinical Efficacy Using a Novel Device) trial, 38% of the patients had prior cardiac implantable electronic devices (CIEDs), while 25% of patients developed new conduction abnormalities necessitating implantation of new CIEDs. Concerns exist regarding trapping existing CIED leads during TTVR. Similarly, transvenous permanent pacemaker implantation post-TTVR has been reported to be associated with valve dysfunction. In this case-based narrative review, we describe case examples of patients with prior CIEDs undergoing TTVR and conduction abnormalities post-TTVR needing a new permanent pacemaker and discuss potential periprocedural strategies for optimal outcomes. Electrophysiologists specializing in periprocedural management of CIEDs, including lead extraction and post-TTVR device management, play a crucial role and should be part of a comprehensive heart team approach for optimal outcomes.</div></div>","PeriodicalId":36053,"journal":{"name":"Structural Heart","volume":"9 9","pages":"Article 100707"},"PeriodicalIF":2.8,"publicationDate":"2025-07-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144907279","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Novel Management to Severe Hypoattenuation Leaflet Thickening Following Transcatheter Aortic Valve Replacement","authors":"Himax Patel MD ,&nbsp;John Lester BS ,&nbsp;Amr Essa MBCHB ,&nbsp;Robert Summers MD ,&nbsp;Dania Al Jabri MD ,&nbsp;Jarren Ypil BS ,&nbsp;Kimberly Atianzar MD ,&nbsp;Musa Sharkawi MBBCH","doi":"10.1016/j.shj.2025.100706","DOIUrl":"10.1016/j.shj.2025.100706","url":null,"abstract":"","PeriodicalId":36053,"journal":{"name":"Structural Heart","volume":"9 10","pages":"Article 100706"},"PeriodicalIF":2.8,"publicationDate":"2025-07-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145027157","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Transcatheter Mitral Valve Replacement Using Contemporary Dedicated Devices: A Systematic Review and Meta-Analysis","authors":"Mark J. Zorman BM BCh ,&nbsp;Katerina Dangas BM BCh ,&nbsp;Jonathan Vibhishanan MB BChir ,&nbsp;James Castle MBChB ,&nbsp;Kate Eastwick-Jones BM BCh ,&nbsp;Marco Coronelli MBBS ,&nbsp;Mohamad S. Alabdaljabar MD ,&nbsp;Kaleb Foster MD ,&nbsp;Danuzia Silva MD, MPH ,&nbsp;Parth Patel MD ,&nbsp;Emma Johns MD ,&nbsp;Palina Piankova MB BCh BAO, MSc ,&nbsp;José Ordóñez-Mena MSc, Dr. sc. hum. ,&nbsp;Sam Dawkins MBBS, DPhil ,&nbsp;James Newton MB ChB, MD ,&nbsp;Mackram F. Eleid MD ,&nbsp;Mayra E. Guerrero MD ,&nbsp;Thomas J. Cahill MBBS, DPhil","doi":"10.1016/j.shj.2025.100702","DOIUrl":"10.1016/j.shj.2025.100702","url":null,"abstract":"<div><h3>Background</h3><div>Dedicated transcatheter mitral valve replacement (TMVR) devices have emerged as a promising strategy for treating mitral regurgitation (MR) in high-risk patients with complex native valve anatomy. Early experience spans multiple devices utilizing both transapical and transseptal access. The aim of this study was to evaluate procedural, 30-day, and midterm outcomes of TMVR with contemporary dedicated mitral devices in patients with native MR.</div></div><div><h3>Methods</h3><div>A systematic search of Medline, Embase, and Cochrane Library (January 2010-January 2025) was conducted. Pooled outcome estimates were derived using random-effects models, excluding legacy devices and cases of mitral stenosis.</div></div><div><h3>Results</h3><div>Thirteen studies (914 patients) were included in the analysis. The mean age was 75.4 years, and 69.8% had functional or mixed MR. Technical success was 96.3%. Residual MR was mild or less in 99% of patients at 30 days and 98% at 1 year. All-cause mortality was 11.0% at 30 days and 26.4% at 1 year. Over a mean follow-up of 12.1 months, rates of heart failure (HF) hospitalizations, cerebrovascular events, and valve reinterventions were 26.2, 5.6, and 6.0 events per 100 patient-years, respectively. Compared with transseptal access, transapical showed higher 30-day major bleeding (19.2% vs. 10.4%, <em>p</em> = 0.03) and all-cause mortality at 30 days (14.0% vs. 4.7%, <em>p</em> ​&lt;0.001) and 1 year (27.7% vs. 13.1%, <em>p</em> = 0.005). Midterm rates of HF readmissions, major bleeding, and valve reinterventions were comparable between access routes.</div></div><div><h3>Conclusions</h3><div>Contemporary dedicated TMVR devices demonstrate high technical success and sustained MR reduction. Transseptal access is associated with lower morbidity and mortality. Further research is needed to improve longer-term mortality and HF hospitalizations following TMVR with dedicated mitral devices.</div></div>","PeriodicalId":36053,"journal":{"name":"Structural Heart","volume":"9 9","pages":"Article 100702"},"PeriodicalIF":2.8,"publicationDate":"2025-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144826623","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An Easy Way to Solve the Stuck Leaflet Causing Aortic Regurgitation Following Transcatheter Aortic Valve Replacement","authors":"Neelima Katukuri MD ,&nbsp;Brian R. Gebhardt MD ,&nbsp;Matthew Lawlor MD ,&nbsp;Jennifer Walker MD ,&nbsp;Nikolaos Kakouros MD, PhD","doi":"10.1016/j.shj.2025.100697","DOIUrl":"10.1016/j.shj.2025.100697","url":null,"abstract":"","PeriodicalId":36053,"journal":{"name":"Structural Heart","volume":"9 10","pages":"Article 100697"},"PeriodicalIF":2.8,"publicationDate":"2025-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145020976","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Single Leaflet Device Attachment After Pascal Implantation for Transcatheter Edge-to-Edge Repair: Systematic Review and Meta-Analysis","authors":"Soumya Gupta MD ,&nbsp;Devika Aggarwal MBBS ,&nbsp;Michael Gao MD ,&nbsp;Kirtipal Bhatia MD ,&nbsp;Marija Petrovic MD, PhD ,&nbsp;Abel Casso Dominguez MD ,&nbsp;Stamatios Lerakis MD, PhD ,&nbsp;Edgar Argulian MD, MPH","doi":"10.1016/j.shj.2025.100698","DOIUrl":"10.1016/j.shj.2025.100698","url":null,"abstract":"","PeriodicalId":36053,"journal":{"name":"Structural Heart","volume":"9 10","pages":"Article 100698"},"PeriodicalIF":2.8,"publicationDate":"2025-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145011255","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluating ChatGPT-4o and OpenEvidence for Structural Heart Disease Support: Insights From Tricuspid Valve Therapies","authors":"Joseph Hajj MD ,&nbsp;Mohamad Mdaihly MD ,&nbsp;Joseph Kassab MD ,&nbsp;Rhonda Miyasaka MD ,&nbsp;Serge C. Harb MD","doi":"10.1016/j.shj.2025.100696","DOIUrl":"10.1016/j.shj.2025.100696","url":null,"abstract":"","PeriodicalId":36053,"journal":{"name":"Structural Heart","volume":"9 9","pages":"Article 100696"},"PeriodicalIF":2.8,"publicationDate":"2025-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144860481","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Echocardiographic Imaging to Guide Tricuspid Interventions","authors":"Rebecca T. Hahn MD","doi":"10.1016/j.shj.2025.100669","DOIUrl":"10.1016/j.shj.2025.100669","url":null,"abstract":"<div><div>Transcatheter tricuspid valve interventions may offer patients less invasive treatment alternatives to surgery. This review evaluates the use of echocardiography to determine anatomic suitability and guide the 2 most common classes of device currently used worldwide to treat tricuspid regurgitation, tricuspid transcatheter edge-to-edge repair, and orthotopic transcatheter tricuspid valve replacement. This review outlines the intraprocedural echocardiographic imaging required for these 2 devices.</div></div>","PeriodicalId":36053,"journal":{"name":"Structural Heart","volume":"9 7","pages":"Article 100669"},"PeriodicalIF":1.4,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144605620","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Understanding Aortic Stenosis and Transcatheter Aortic Valve Replacement in Women","authors":"Giulia Masiero MD ,&nbsp;Anna Franzone MD, PhD ,&nbsp;Valeria Paradies MD ,&nbsp;Nicole Karam MD, PhD ,&nbsp;Chiara Fraccaro MD, PhD ,&nbsp;Chiara De Biase MD ,&nbsp;Mirvat Alasnag MD ,&nbsp;Giulia Botti MD ,&nbsp;Angelicarosa Cascone MD ,&nbsp;Ana Belen Cid-Alvarez MD, PhD ,&nbsp;Tanja K. Rudolph MD, PhD ,&nbsp;Marta Kaluzna-Oleksy MD, PhD ,&nbsp;Stephane Manzo-Silberman MD, PhD ,&nbsp;Julinda Mehilli MD, PhD ,&nbsp;Barbara E. Stähli MD, PhD ,&nbsp;Julia Grapsa MD, PhD ,&nbsp;Kyriakos Panaou MD ,&nbsp;Barbara Bellini MD ,&nbsp;Joanna J. Wykrzykowska MD, PhD ,&nbsp;Sabine Bleiziffer MD, PhD ,&nbsp;Alaide Chieffo MD, PhD","doi":"10.1016/j.shj.2025.100666","DOIUrl":"10.1016/j.shj.2025.100666","url":null,"abstract":"<div><div>The impact of sex on the baseline characteristics, morphology, and clinical presentation of degenerative aortic stenosis (AS) is well-documented but remains poorly understood. Unlike valve surgery, for which patients have been predominantly male, percutaneous treatment of AS has shown balanced representation of both sexes, with women demonstrating greater benefit from transfemoral aortic valve replacement compared to surgical treatment. This review explores sex-specific differences in the epidemiology, pathophysiology, diagnostic challenges, treatment approaches, and clinical outcomes of degenerative AS. Furthermore, it addresses technical, sex-specific considerations in transfemoral aortic valve replacement, including preprocedural screening, device selection, implantation strategy, and postprocedural management.</div></div>","PeriodicalId":36053,"journal":{"name":"Structural Heart","volume":"9 7","pages":"Article 100666"},"PeriodicalIF":1.4,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144605618","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pharmacology in Structural Intervention for Valvular Heart Disease: Current Practice and Future Perspectives","authors":"Francesca Maria Di Muro MD ,&nbsp;Birgit Vogel MD ,&nbsp;Angelo Oliva MD ,&nbsp;Benjamin Bay MD ,&nbsp;Mauro Gitto MD ,&nbsp;George D. Dangas MD, PhD ,&nbsp;Roxana Mehran MD","doi":"10.1016/j.shj.2024.100360","DOIUrl":"10.1016/j.shj.2024.100360","url":null,"abstract":"<div><div>Over the past 2 decades, structural heart interventions–including procedures like transcatheter aortic valve replacement, transcatheter mitral or tricuspid valve replacement, and transcatheter edge-to-edge mitral or tricuspid valve repair–have emerged as feasible alternatives to traditional surgery for treating valvular heart diseases. Antithrombotic treatment represents a critical aspect of postoperative care, aiming to balance the thromboembolic risk due to the incorporation of prosthetic materials and the consequently altered hemodynamics within the cardiac chambers with the bleeding risk depending on patients’ and procedural factors. This continuously evolving interplay underscores the importance of personalized, evidence-based approaches to ensure optimal outcomes. This review provides a comprehensive examination of the current knowledge on antithrombotic therapies after structural interventions, offering insights into the evolving field and emphasizing the importance of tailored strategies.</div></div>","PeriodicalId":36053,"journal":{"name":"Structural Heart","volume":"9 7","pages":"Article 100360"},"PeriodicalIF":1.4,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144605624","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}