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Bridging the gap between science and society: long-term effects of the Healthy Lifestyle Community Programme (HLCP, cohort 1) on weight and the metabolic risk profile: a controlled study. 弥合科学与社会之间的差距:健康生活方式社区计划(HLCP,队列1)对体重和代谢风险概况的长期影响:一项对照研究。
Pub Date : 2022-02-22 eCollection Date: 2022-01-01 DOI: 10.1136/bmjnph-2021-000340
Corinna Anand, Ragna-Marie Kranz, Sarah Husain, Christian Koeder, Nora Schoch, Dima-Karam Alzughayyar, Reinhold Gellner, Karin Hengst, Heike Englert

Background: The potential of adopting a healthy lifestyle to fight non-communicable diseases (NCDs) is not fully used. We hypothesised that the Healthy Lifestyle Community Programme (HLCP, cohort 1) reduces weight and other risk markers compared with baseline and control.

Methods: 24-month, non-randomised, controlled intervention trial. Intervention: intensive 8-week phase with seminars, workshops and coaching focusing on a healthy lifestyle (eg, plant-based diet, physical activity, stress management) and group support followed by a 22-month alumni phase. Weight reduction as the primary outcome and other NCD risk parameters were assessed at six time points. Participants were recruited from the general population. Multiple linear regression analyses were conducted.

Results: 143 participants (58±12 years, 71% female) were enrolled (91 in the intervention (IG) and 52 in the control group (CG)). Groups' baseline characteristics were comparable, except participants of IG were younger, more often females, overweight and reported lower energy intake (kcal/day). Weight significantly decreased in IG at all follow-ups by -1.5 ± 1.9 kg after 8 weeks to -1.9 ± 4.0 kg after 24 months and more than in CG (except after 24 months). Being male, in the IG or overweight at baseline and having a university degree predicted more weight loss. After the intervention, there were more participants in the IG with a 'high' adherence (+12%) to plant-based food patterns. The change of other risk parameters was most distinct after 8 weeks and in people at elevated risk. Diabetes-related risk parameters did not improve.

Conclusion: The HLCP was able to reduce weight and to improve aspects of the NCD risk profile. Weight loss in the IG was moderate but maintained for 24 months. Participants of lower educational status might benefit from even more practical units. Future interventions should aim to include more participants at higher risk.

Trial registration number: DRKS00018821.

背景:采用健康的生活方式来防治非传染性疾病的潜力尚未得到充分利用。我们假设,与基线和对照组相比,健康生活方式社区计划(HLCP,队列1)降低了体重和其他风险指标。方法:为期24个月的非随机对照干预试验。干预:密集的8周阶段,包括研讨会、讲习班和指导,重点是健康的生活方式(例如,植物性饮食、体育活动、压力管理)和小组支持,随后是22个月的校友阶段。在6个时间点评估体重减轻作为主要结局和其他非传染性疾病风险参数。参与者是从普通人群中招募的。进行多元线性回归分析。结果:共纳入143例(58±12岁,71%为女性),其中干预组(IG) 91例,对照组(CG) 52例。各组的基线特征具有可比性,除了IG的参与者更年轻,更常见的是女性,超重和报告的能量摄入(千卡/天)较低。在所有随访中,IG组的体重在8周后显著下降-1.5±1.9 kg,在24个月后显著下降-1.9±4.0 kg,并且比CG组下降更多(24个月后除外)。男性,在IG或超重基线和拥有大学学位预测更多的体重减轻。干预后,IG中有更多的参与者对植物性食物模式的“高”依从性(+12%)。其他风险参数的变化在8周后和高风险人群中最为明显。糖尿病相关的风险参数没有改善。结论:HLCP能够减轻体重并改善非传染性疾病风险概况。大鼠体重减轻幅度不大,但持续了24个月。教育程度较低的参与者可能会从更实用的单元中受益。未来的干预措施应旨在包括更多的高风险参与者。试验注册号:DRKS00018821。
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引用次数: 4
Global architecture for the nutrition training of health professionals: a scoping review and blueprint for next steps. 卫生专业人员营养培训的全球架构:范围审查和下一步行动蓝图。
IF 3.3 Q2 NUTRITION & DIETETICS Pub Date : 2022-02-16 eCollection Date: 2022-01-01 DOI: 10.1136/bmjnph-2021-000354
Breanna Lepre, Helena Trigueiro, Jørgen Torgerstuen Johnsen, Ali Ahsan Khalid, Lauren Ball, Sumantra Ray

Background: This paper provides an overview of capacity-building efforts in the context of nutrition education for medical and healthcare professionals.

Methods: Content analysis of eighteen reports related to nutrition education and capacity building, and interviews with key personnel from the WHO and NNEdPro Global Centre for Nutrition and Health were synthesised. Recommendations to improve nutrition education and subsequent nutrition capacity of healthcare professionals were identified based on policy guidance and interviews.

Findings: Most included documents noted the importance of nutrition education and capacity building for medical and healthcare professionals. Healthcare professionals and the 'health sector' were positioned as central to achieving improved public health, and the promotion of nutrition knowledge and awareness in the general population.

Conclusion: Increased focus on nutrition education and capacity of the health workforce are key to improvements in population health and well-being. The WHO is well placed to support global nutrition education.

Recommendations: Key recommendations from the literature review and interviews include improved global data collection mechanisms, a pledge from governments to prioritise nutrition education and capacity building, along with implementation of standardised nutrition curricula for all healthcare sectors. This would include the development and expansion of on-line resources.

背景:本文概述了在医疗和保健专业人员营养教育方面的能力建设工作:方法:对 18 份与营养教育和能力建设相关的报告进行了内容分析,并对世界卫生组织和 NNEdPro 全球营养与健康中心的主要人员进行了访谈。在政策指导和访谈的基础上,确定了改善营养教育和医疗保健专业人员后续营养能力的建议:大多数收录的文件都指出了营养教育和医疗保健专业人员能力建设的重要性。医疗保健专业人员和 "卫生部门 "被定位为改善公众健康、促进营养知识普及和提高公众营养意识的核心:结论:加强对营养教育的重视和提高卫生工作者的能力是改善人口健康和福祉的关键。世卫组织完全有能力支持全球营养教育:文献综述和访谈提出的主要建议包括:改进全球数据收集机制;各国政府承诺将营养教育和能力建设列为优先事项;在所有卫生保健部门实施标准化营养课程。这将包括开发和扩大在线资源。
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引用次数: 0
Food insecurity and men's perpetration of partner violence in a longitudinal cohort in South Africa. 粮食不安全与南非男性实施伴侣暴力的纵向队列研究
Pub Date : 2022-02-07 eCollection Date: 2022-01-01 DOI: 10.1136/bmjnph-2021-000288
Abigail M Hatcher, Torsten B Neilands, Dumisani Rebombo, Sheri D Weiser, Nicola J Christofides

Background: Although food insecurity has been associated with intimate partner violence (IPV), few studies examine it longitudinally or among male perpetrators.

Methods: We used secondary data from a trial that followed 2479 men in a peri-urban settlement in South Africa (February 2016-August 2018). Men self-completed questionnaires at baseline (T0), 12 months (T1) and 24 months (T2) on food security, household type, relationship status, childhood abuse exposure, alcohol use, and perpetration of physical and/or sexual IPV. Cross-lagged dynamic panel modelling examines the strength and direction of associations over time.

Results: At baseline, rates of IPV perpetration (52.0%) and food insecurity (65.5%) were high. Food insecure men had significantly higher odds of IPV perpetration at T0, T1 and T2 (ORs of 1.9, 1.4 and 1.4, respectively). In longitudinal models, food insecurity predicted men's IPV perpetration 1 year later. The model had excellent fit after controlling for housing, relationship status, age, childhood abuse and potential effect of IPV on later food insecurity (standardised coefficient=0.09, p=0.031. root mean squared error of approximation=0.016, comparative fit index=0.994). IPV perpetration did not predict later food security (p=0.276).

Conclusion: Food insecurity had an independent, longitudinal association with men's IPV perpetration in a peri-urban South African settlement. These findings suggest food security could be a modifiable risk factor of partner violence.

Trial registration number: NCT02823288.

背景:虽然粮食不安全与亲密伴侣暴力(IPV)有关,但很少有研究对其进行纵向或男性施暴者的调查。方法:我们使用了一项试验的辅助数据,该试验追踪了南非近郊定居点的2479名男性(2016年2月- 2018年8月)。男性在基线(T0)、12个月(T1)和24个月(T2)时自行完成问卷,内容涉及食品安全、家庭类型、关系状况、童年受虐经历、酒精使用以及身体和/或性IPV的实施。交叉滞后动态面板模型检验了随时间关联的强度和方向。结果:在基线时,IPV发生率(52.0%)和粮食不安全发生率(65.5%)较高。食物不安全的男性在第0、T1和T2发生IPV的几率明显更高(or分别为1.9、1.4和1.4)。在纵向模型中,粮食不安全可以预测1年后男性的IPV行为。在控制了住房、关系状况、年龄、童年虐待和IPV对后期粮食不安全的潜在影响后,模型具有很好的拟合性(标准化系数=0.09,p=0.031)。近似均方根误差=0.016,比较拟合指数=0.994)。IPV犯罪不能预测后来的粮食安全(p=0.276)。结论:在南非城郊定居点,粮食不安全与男性IPV犯罪具有独立的纵向关联。这些发现表明,食品安全可能是伴侣暴力的一个可改变的风险因素。试验注册号:NCT02823288。
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引用次数: 7
Potential effect of real-world junk food and sugar-sweetened beverage taxes on population health, health system costs and greenhouse gas emissions in New Zealand: a modelling study. 垃圾食品和含糖饮料税对新西兰人口健康、卫生系统成本和温室气体排放的潜在影响:一项模型研究。
Pub Date : 2022-02-07 eCollection Date: 2022-01-01 DOI: 10.1136/bmjnph-2021-000376
Leah Grout, Anja Mizdrak, Nhung Nghiem, Amanda C Jones, Tony Blakely, Cliona Ni Mhurchu, Christine Cleghorn

Poor diet is a major risk factor for excess weight gain and obesity-related diseases, including cardiovascular diseases, type 2 diabetes mellitus, osteoarthritis and several cancers. This paper aims to assess the potential impacts of real-world food and beverage taxes on change in dietary risk factors, health gains (in quality-adjusted life years (QALYs)), health system costs and greenhouse gas (GHG) emissions as if they had all been implemented in New Zealand (NZ). Ten taxes or tax packages were modelled. A proportional multistate life table model was used to predict resultant QALYs and costs over the remaining lifespan of the NZ population alive in 2011, as well as GHG emissions. QALYs ranged from 12.5 (95% uncertainty interval (UI) 10.2 to 15.0; 3% discount rate) per 1000 population for the import tax on sugar-sweetened beverages (SSB) in Palau to 143 (95% UI 118 to 171) per 1000 population for the excise duties on saturated fat, chocolate and sweets in Denmark, while health expenditure savings ranged from 2011 NZ$245 (95% UI 188 to 310; 2020 US$185) per capita to NZ$2770 (95% UI 2140 to 3480; US$2100) per capita, respectively. The modelled taxes resulted in decreases in GHG emissions from baseline diets, ranging from -0.2% for the tax on SSB in Barbados to -2.8% for Denmark's tax package. There is strong evidence for the implementation of food and beverage tax packages in NZ or similar high-income settings.

不良饮食习惯是导致体重过度增加和肥胖相关疾病的主要风险因素,包括心血管疾病、2型糖尿病、骨关节炎和几种癌症。本文旨在评估现实世界食品和饮料税对饮食风险因素、健康收益(质量调整生命年(QALYs))、卫生系统成本和温室气体(GHG)排放变化的潜在影响,就好像它们都在新西兰(NZ)实施一样。我们模拟了10种税种或一揽子税种。使用比例多状态生命表模型来预测2011年新西兰人口剩余寿命的最终质量年和成本,以及温室气体排放。qaly范围为12.5(95%不确定度区间(UI) 10.2 ~ 15.0;在帕劳,含糖饮料进口税(3%折扣率)为每1000人143纽币(95%纽币118至171),在丹麦,饱和脂肪、巧克力和糖果的消费税为每1000人143纽币(95%纽币188至310),而医疗支出节省从2011年245纽币(95%纽币188至310)不等;2020年人均185美元)至2770新西兰元(95% UI 2140至3480;人均2100美元)。模拟的税收导致基线饮食的温室气体排放量减少,从巴巴多斯的SSB税-0.2%到丹麦的一揽子税收-2.8%不等。有强有力的证据表明,在新西兰或类似的高收入环境中实施食品和饮料税一揽子计划。
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引用次数: 3
Overweight and obesity as risk factors for COVID-19-associated hospitalisations and death: systematic review and meta-analysis. 超重和肥胖是与covid -19相关的住院和死亡的危险因素:系统回顾和荟萃分析
Pub Date : 2022-01-19 eCollection Date: 2022-01-01 DOI: 10.1136/bmjnph-2021-000375
Wendemi Sawadogo, Medhin Tsegaye, Andinet Gizaw, Tilahun Adera

Objective: To quantify the current weight of evidence of the association between overweight and obesity as risk factors for COVID-19-related hospitalisations (including hospital admission, intensive care unit admission, invasive mechanical ventilation) and death, and to assess the magnitude of the association and the potential dose-response relationships.

Design: PubMed, Embase, Cochrane, Web of Sciences, WHO COVID-19 database and Google Scholar were used to identify articles published up to 20 July 2021. Peer-reviewed studies reporting adjusted estimates of the association between overweight or obesity and COVID-19 outcomes were included. Three authors reviewed the articles and agreed. The quality of eligible studies was assessed using the Newcastle-Ottawa Quality Assessment Scale. Random-effects meta-analysis was used to estimate the combined effects.

Results: A total of 208 studies with 3 550 997 participants from over 32 countries were included in this meta-analysis. Being overweight was associated with an increased risk of COVID-19-related hospitalisations (OR 1.19, 95% CI 1.12 to 1.28, n=21 studies), but not death (OR 1.02, 95% CI 0.92 to 1.13, n=21). However, patients with obesity were at increased risk of both COVID-19-related hospitalisations (OR 1.72, 95% CI 1.62 to 1.84, n=58) and death (OR 1.25, 95% CI 1.19 to 1.32, n=77). Similarly, patients with extreme obesity were at increased risk of COVID-19-related hospitalisations (OR 2.53, 95% CI 1.67 to 3.84, n=12) and death (OR 2.06, 95% CI 1.76 to 3.00, n=19). There was a linear dose-response relationship between these obesity categories and COVID-19 outcomes, but the strength of the association has decreased over time.

Conclusion: Being overweight increases the risk of COVID-19-related hospitalisations but not death, while obesity and extreme obesity increase the risk of both COVID-19-related hospitalisations and death. These findings suggest that prompt access to COVID-19 care, prioritisation for COVID-19 vaccination and other preventive measures are warranted for this vulnerable group.

目的:量化超重和肥胖作为covid -19相关住院(包括住院、重症监护病房住院、有创机械通气)和死亡危险因素之间关联的证据的当前权重,并评估这种关联的程度和潜在的剂量-反应关系。设计:使用PubMed、Embase、Cochrane、Web of Sciences、WHO COVID-19数据库和Google Scholar来识别截至2021年7月20日发表的文章。纳入了报告超重或肥胖与COVID-19结局之间关系的经同行评审的研究。三位作者审阅了这些文章并表示同意。使用纽卡斯尔-渥太华质量评估量表评估符合条件的研究的质量。随机效应荟萃分析用于估计综合效应。结果:本荟萃分析共纳入了来自32个国家的208项研究,涉及3 550 997名受试者。超重与covid -19相关住院的风险增加相关(OR 1.19, 95% CI 1.12至1.28,n=21项研究),但与死亡无关(OR 1.02, 95% CI 0.92至1.13,n=21)。然而,肥胖患者与covid -19相关的住院治疗(OR 1.72, 95% CI 1.62至1.84,n=58)和死亡(OR 1.25, 95% CI 1.19至1.32,n=77)的风险都增加了。同样,极度肥胖的患者与covid -19相关的住院治疗(OR 2.53, 95% CI 1.67至3.84,n=12)和死亡(OR 2.06, 95% CI 1.76至3.00,n=19)的风险增加。这些肥胖类别与COVID-19结局之间存在线性剂量反应关系,但这种关联的强度随着时间的推移而减弱。结论:超重会增加与covid -19相关的住院风险,但不会增加死亡风险,而肥胖和极度肥胖会增加与covid -19相关的住院和死亡风险。这些发现表明,有必要为这一弱势群体及时提供COVID-19护理,优先接种COVID-19疫苗并采取其他预防措施。
{"title":"Overweight and obesity as risk factors for COVID-19-associated hospitalisations and death: systematic review and meta-analysis.","authors":"Wendemi Sawadogo,&nbsp;Medhin Tsegaye,&nbsp;Andinet Gizaw,&nbsp;Tilahun Adera","doi":"10.1136/bmjnph-2021-000375","DOIUrl":"https://doi.org/10.1136/bmjnph-2021-000375","url":null,"abstract":"<p><strong>Objective: </strong>To quantify the current weight of evidence of the association between overweight and obesity as risk factors for COVID-19-related hospitalisations (including hospital admission, intensive care unit admission, invasive mechanical ventilation) and death, and to assess the magnitude of the association and the potential dose-response relationships.</p><p><strong>Design: </strong>PubMed, Embase, Cochrane, Web of Sciences, WHO COVID-19 database and Google Scholar were used to identify articles published up to 20 July 2021. Peer-reviewed studies reporting adjusted estimates of the association between overweight or obesity and COVID-19 outcomes were included. Three authors reviewed the articles and agreed. The quality of eligible studies was assessed using the Newcastle-Ottawa Quality Assessment Scale. Random-effects meta-analysis was used to estimate the combined effects.</p><p><strong>Results: </strong>A total of 208 studies with 3 550 997 participants from over 32 countries were included in this meta-analysis. Being overweight was associated with an increased risk of COVID-19-related hospitalisations (OR 1.19, 95% CI 1.12 to 1.28, n=21 studies), but not death (OR 1.02, 95% CI 0.92 to 1.13, n=21). However, patients with obesity were at increased risk of both COVID-19-related hospitalisations (OR 1.72, 95% CI 1.62 to 1.84, n=58) and death (OR 1.25, 95% CI 1.19 to 1.32, n=77). Similarly, patients with extreme obesity were at increased risk of COVID-19-related hospitalisations (OR 2.53, 95% CI 1.67 to 3.84, n=12) and death (OR 2.06, 95% CI 1.76 to 3.00, n=19). There was a linear dose-response relationship between these obesity categories and COVID-19 outcomes, but the strength of the association has decreased over time.</p><p><strong>Conclusion: </strong>Being overweight increases the risk of COVID-19-related hospitalisations but not death, while obesity and extreme obesity increase the risk of both COVID-19-related hospitalisations and death. These findings suggest that prompt access to COVID-19 care, prioritisation for COVID-19 vaccination and other preventive measures are warranted for this vulnerable group.</p>","PeriodicalId":36307,"journal":{"name":"BMJ Nutrition, Prevention and Health","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-01-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/20/4e/bmjnph-2021-000375.PMC8783972.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40592934","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 48
Consumption of industrial processed foods and risk of premenopausal breast cancer among Latin American women: the PRECAMA study. 拉丁美洲妇女食用工业加工食品与绝经前乳腺癌风险:PRECAMA 研究。
Pub Date : 2022-01-04 eCollection Date: 2022-01-01 DOI: 10.1136/bmjnph-2021-000335
Isabelle Romieu, Neha Khandpur, Aikaterini Katsikari, Carine Biessy, Gabriela Torres-Mejía, Angélica Ángeles-Llerenas, Isabel Alvarado-Cabrero, Gloria Inés Sánchez, Maria Elena Maldonado, Carolina Porras, Ana Cecilia Rodriguez, Maria Luisa Garmendia, Vèronique Chajés, Elom K Aglago, Peggy L Porter, MingGang Lin, Mathilde His, Marc J Gunter, Inge Huybrechts, Sabina Rinaldi

Ultra-processed food intake has been linked to an increased risk of breast cancer in Western populations. No data are available in the Latin American population although the consumption of ultra-processed foods is increasing rapidly in this region. We evaluated the association of ultra-processed food intake to breast cancer risk in a case-control study including 525 cases (women aged 20-45 years) and 525 matched population-based controls from Chile, Colombia, Costa Rica and Mexico. The degree of processing of foods was classified according to the NOVA classification. Overall, the major contributors to ultra-processed food intake were ready-to-eat/heat foods (18.2%), cakes and desserts (16.7%), carbonated and industrial fruit juice beverages (16.7%), breakfast cereals (12.9%), sausages and reconstituted meat products (12.1%), industrial bread (6.1%), dairy products and derivatives (7.6%) and package savoury snacks (6.1%). Ultra-processed food intake was positively associated with the risk of breast cancer in adjusted models (OR T3-T1=1.93; 95% CI=1.11 to 3.35). Specifically, a higher risk was observed with oestrogen receptor positive breast cancer (ORT3-T1=2.44, (95% CI=1.01 to 5.90, P-trend=0.049), while no significant association was observed with oestrogen receptor negative breast cancer (ORT3-T1=1.87, 95% CI=0.43 to 8.13, P-trend=0.36). Our findings suggest that the consumption of ultra-processed foods might increase the risk of breast cancer in young women in Latin America. Further studies should confirm these findings and disentangle specific mechanisms relating ultra-processed food intake and carcinogenic processes in the breast.

在西方人口中,超加工食品的摄入与乳腺癌风险的增加有关。虽然超加工食品的摄入量在拉美地区迅速增加,但该地区尚无相关数据。我们在一项病例对照研究中评估了超加工食品摄入量与乳腺癌风险的关系,该研究包括来自智利、哥伦比亚、哥斯达黎加和墨西哥的 525 例病例(20-45 岁女性)和 525 例匹配的人群对照。食品的加工程度根据诺瓦分类法进行了分类。总体而言,超加工食品摄入量的主要来源是即食/加热食品(18.2%)、蛋糕和甜点(16.7%)、碳酸饮料和工业果汁饮料(16.7%)、早餐谷物(12.9%)、香肠和重组肉制品(12.1%)、工业面包(6.1%)、乳制品及其衍生物(7.6%)和包装咸味零食(6.1%)。在调整模型中,超加工食品摄入量与乳腺癌风险呈正相关(OR T3-T1=1.93; 95% CI=1.11至3.35)。具体而言,雌激素受体阳性乳腺癌的风险更高(ORT3-T1=2.44,(95% CI=1.01至5.90,P-趋势=0.049),而雌激素受体阴性乳腺癌的风险则不明显(ORT3-T1=1.87,95% CI=0.43至8.13,P-趋势=0.36)。我们的研究结果表明,食用超加工食品可能会增加拉丁美洲年轻女性罹患乳腺癌的风险。进一步的研究应证实这些发现,并阐明超加工食品摄入量与乳腺癌致癌过程之间的具体机制。
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引用次数: 0
Serious vitamin D deficiency in healthcare workers during the COVID-19 pandemic. COVID-19大流行期间卫生保健工作者严重缺乏维生素D。
Pub Date : 2022-01-04 eCollection Date: 2022-01-01 DOI: 10.1136/bmjnph-2021-000364
Takanori Funaki, Makiko Sanpei, Naho Morisaki, Tetsuya Mizoue, Koushi Yamaguchi
Several reports suggest that vitamin D (VitD) deficiency could increase the predisposition to systemic infection, including respiratory tract infections and impaired immune response. A recent metaanalysis demonstrated that VitD supplementation can reduce the risk of respiratory tract infections overall based on data from randomised controlled trials. Moreover, an article reported a possible association of VitD level with cytokine storm and unregulated inflammation in elderly patients with COVID19. It supported the potential protective impact of VitD by enhancing the immune system and possibly reducing the risk of complications associated with cytokine storm and unregulated inflammation in patients with severe COVID19. VitD is a lipidsoluble vitamin that acts as a ligand to the intranuclear receptor superfamily and plays a significant role in regulating between innate and acquired immunity. 25Hydroxy vitamin D (25(OH)D) is the major circulating form of VitD in humans and currently accepted as the best marker of VitD status. To date, there are only a few reports focusing on nutritional status including 25(OH)D in healthcare workers (HCWs) during the COVID19 pandemic. During the COVID19 pandemic, we conducted a prospective observational study to evaluate several blood markers in HCWs at high risk of SARSCoV2 infection at the National Center for Child Health and Development in Tokyo, Japan. Blood sampling was performed from the enrolled participants from 1 March 2021 to 5 March 2021, and all clinical laboratory testing of the blood including VitD, zinc and natural killer (NK) cell activity were examined at the SRL Hachioji Laboratory Complex, in Tokyo, Japan. 25(OH)D was measured using chemiluminescent enzyme immunoassay, and serum zinc level was determined using the colorimetric method. Also, chromium51 release assay was used to assess the NK cell activity. We analysed the relationship between gender and VitD levels using the Fisher’s exact test. In addition, the correlationship between VitD levels and age was Letter
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引用次数: 2
Longitudinal study of the effects of price and promotion incentives on purchases of unhealthy foods: evidence for restricting food promotions. 价格和促销激励对不健康食品购买影响的纵向研究:限制食品促销的证据。
Pub Date : 2022-01-01 DOI: 10.1136/bmjnph-2021-000323
Daniel Kopasker, Ourega-Zoé Ejebu, Patricia Norwood, Anne Ludbrook

Objectives: Taxes and restrictions on promotions have recently been proposed as policy instruments to reduce consumption of unhealthy foods. The objective of this study is to add to the limited evidence on the comparative effectiveness of price changes, price promotions and volume promotions in changing household purchasing of unhealthy foods, using biscuits, crisps and savoury snacks as examples.

Design: Longitudinal regression analysis of consumer microdata.

Setting: Secondary data on itemised household purchases of biscuits, crisps and savoury snacks from 2006 to 2012.

Participants: Sample of 3024 households in Scotland.

Main outcome measures: Changes in the number of calories (kcal) purchased in the product category by a household caused by changes in the price for the product category, any temporary in-store price promotions and any temporary in-store volume promotions. Changes are measured at the mean, median, 25th percentile and 75th percentile of the household purchasing distribution for the full sample. Subgroup analyses were conducted by household income band and for households with and without children.

Results: Between product categories, the scale of purchasing response to incentives varies significantly. Within product categories, the mean calories (kcal) purchased by a household are more responsive to any volume promotion than to price or any price promotion for all product categories. As the volume of items purchased increases, households are less responsive to price, less responsive to any volume promotion and more responsive to any price promotion. Statistically significant differences are observed between household income groups in their response to price and promotion incentives within the biscuits category only. In cases where statistically significant differences are observed, households with children are more responsive to promotion and price incentives than households without children.

Conclusions: For all product categories analysed (biscuits, crisps and savoury snacks), household purchasing is most responsive to any volume promotion. Therefore, assuming the response of consumers to incentives remains constant following legislation, the most effective policy instrument to reduce the calorie intake from these products may be a ban on volume promotions.

目标:最近提议将税收和限制促销作为减少不健康食品消费的政策工具。本研究的目的是补充有限的证据,价格变化,价格促销和数量促销在改变家庭购买不健康食品方面的相对有效性,以饼干,薯片和咸味零食为例。设计:对消费者微观数据进行纵向回归分析。背景:2006年至2012年家庭购买饼干、薯片和咸味零食的分项数据。参与者:苏格兰3024个家庭的样本。主要结果测量:由于产品类别的价格变化、任何临时店内价格促销和任何临时店内数量促销引起的家庭在产品类别中购买的卡路里数量(kcal)的变化。变化是在整个样本的家庭购买分布的平均值、中位数、第25百分位和第75百分位进行测量的。按家庭收入等级、有孩子和没有孩子的家庭进行亚组分析。结果:在不同的产品类别之间,消费者对激励的购买反应规模存在显著差异。在产品类别中,家庭购买的平均卡路里(kcal)对任何数量促销的反应比对所有产品类别的价格或任何价格促销的反应更敏感。随着购买物品数量的增加,家庭对价格的反应变弱,对数量促销的反应变弱,对价格促销的反应变强。仅在饼干类别中,不同家庭收入群体对价格和促销激励的反应在统计上存在显著差异。在观察到统计上显著差异的情况下,有孩子的家庭比没有孩子的家庭对促销和价格激励的反应更积极。结论:对于所分析的所有产品类别(饼干、薯片和咸味零食),家庭购买对任何批量促销的反应最积极。因此,假设消费者对激励措施的反应在立法后保持不变,那么减少这些产品卡路里摄入量的最有效政策工具可能是禁止批量促销。
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引用次数: 0
Changes to local area public sector spending and food purchasing in England: a longitudinal ecological study. 英格兰地方公共部门支出和食品购买的变化:一项纵向生态学研究。
Pub Date : 2022-01-01 DOI: 10.1136/bmjnph-2021-000346
Rosemary H Jenkins, Eszter P Vamos, David Taylor-Robinson, Kate E Mason, Anthony A Laverty

Objectives: Changes in public sector service spending may influence food consumption. We make use of changing local authority (LA) expenditure in England to assess impacts on food purchasing. We examine total LA service spending and explore two potential pathways: highways and transport spending which may affect access to food; and housing service expenditure which may affect household resources available to purchase foods.

Design: Longitudinal panel survey at the LA level (2008-2015) using fixed effects linear regression.

Setting: 324 LAs in England.

Main exposure: Expenditure per capita on total LA services, highways and transport services, and housing services.

Main outcome measures: LA area estimates of purchasing of fresh fruits and vegetables, high in fat, sugar and salt (HFSS) foods, and takeaways at home, expressed as a percentage of total food and drink expenditure.

Results: Total LA service spending decreased by 17% on average between 2008 and 2015. A 10% decrease in total LA spending was associated with a 0.071 percentage point decrease in HFSS (95% CI -0.093 to -0.050) and a 0.015 percentage point increase in takeaways (95% CI 0.006 to 0.024). A 10% decrease in highways and transport expenditure was associated with a 0.006 percentage point decrease in fruit and vegetable purchasing (95% CI -0.009 to -0.002) and a 0.006 percentage point increase in takeaway purchasing (95% CI 0.001 to 0.010). These associations were seen in urban areas only when analyses were stratified by rural/urban area status. A 0.006 percentage point decrease in HFSS purchasing was also seen with a 10% decrease in housing expenditure (95% CI -0.010 to -0.002).

Conclusion: Changes in LA spending may have impacts on food purchasing which are evident at the area level. This suggests that in addition to more prominent impacts such as foodbank use, austerity measures may have mixed impacts on food purchasing behaviours among the wider population. Individual-level research is needed to further elucidate these relationships.

目标:公共部门服务支出的变化可能影响食品消费。我们利用英格兰不断变化的地方当局(LA)支出来评估对食品采购的影响。我们研究了洛杉矶的总服务支出,并探索了两种潜在的途径:可能影响食物获取的高速公路和运输支出;以及住房服务支出,这可能会影响家庭可用于购买食物的资源。设计:采用固定效应线性回归在洛杉矶水平进行纵向面板调查(2008-2015)。设置:英国324个LAs。主要暴露:总洛杉矶服务、公路和运输服务以及住房服务的人均支出。主要结果测量:洛杉矶地区购买新鲜水果和蔬菜、高脂肪、高糖和高盐(HFSS)食品和在家外卖的估计,以食品和饮料总支出的百分比表示。结果:2008年至2015年间,洛杉矶服务总支出平均下降了17%。洛杉矶总支出减少10%与HFSS减少0.071个百分点(95% CI -0.093至-0.050)和外卖增加0.015个百分点(95% CI 0.006至0.024)相关。公路和运输支出减少10%,水果和蔬菜购买量减少0.006个百分点(95%可信区间为-0.009至-0.002),外卖购买量增加0.006个百分点(95%可信区间为0.001至0.010)。只有在按农村/城市地区状况分层分析时,才能在城市地区看到这些关联。住房支出减少10%(95%置信区间为-0.010至-0.002),家庭资费支出减少0.006个百分点。结论:洛杉矶消费的变化可能对食品购买产生影响,这在地区层面上是明显的。这表明,除了食物银行的使用等更突出的影响外,紧缩措施可能对更广泛人群的食品购买行为产生混合影响。个人层面的研究需要进一步阐明这些关系。
{"title":"Changes to local area public sector spending and food purchasing in England: a longitudinal ecological study.","authors":"Rosemary H Jenkins,&nbsp;Eszter P Vamos,&nbsp;David Taylor-Robinson,&nbsp;Kate E Mason,&nbsp;Anthony A Laverty","doi":"10.1136/bmjnph-2021-000346","DOIUrl":"https://doi.org/10.1136/bmjnph-2021-000346","url":null,"abstract":"<p><strong>Objectives: </strong>Changes in public sector service spending may influence food consumption. We make use of changing local authority (LA) expenditure in England to assess impacts on food purchasing. We examine total LA service spending and explore two potential pathways: highways and transport spending which may affect access to food; and housing service expenditure which may affect household resources available to purchase foods.</p><p><strong>Design: </strong>Longitudinal panel survey at the LA level (2008-2015) using fixed effects linear regression.</p><p><strong>Setting: </strong>324 LAs in England.</p><p><strong>Main exposure: </strong>Expenditure per capita on total LA services, highways and transport services, and housing services.</p><p><strong>Main outcome measures: </strong>LA area estimates of purchasing of fresh fruits and vegetables, high in fat, sugar and salt (HFSS) foods, and takeaways at home, expressed as a percentage of total food and drink expenditure.</p><p><strong>Results: </strong>Total LA service spending decreased by 17% on average between 2008 and 2015. A 10% decrease in total LA spending was associated with a 0.071 percentage point decrease in HFSS (95% CI -0.093 to -0.050) and a 0.015 percentage point increase in takeaways (95% CI 0.006 to 0.024). A 10% decrease in highways and transport expenditure was associated with a 0.006 percentage point decrease in fruit and vegetable purchasing (95% CI -0.009 to -0.002) and a 0.006 percentage point increase in takeaway purchasing (95% CI 0.001 to 0.010). These associations were seen in urban areas only when analyses were stratified by rural/urban area status. A 0.006 percentage point decrease in HFSS purchasing was also seen with a 10% decrease in housing expenditure (95% CI -0.010 to -0.002).</p><p><strong>Conclusion: </strong>Changes in LA spending may have impacts on food purchasing which are evident at the area level. This suggests that in addition to more prominent impacts such as foodbank use, austerity measures may have mixed impacts on food purchasing behaviours among the wider population. Individual-level research is needed to further elucidate these relationships.</p>","PeriodicalId":36307,"journal":{"name":"BMJ Nutrition, Prevention and Health","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9237904/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9107663","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparing McDonald's food marketing practices on official Instagram accounts across 15 countries. 比较麦当劳在15个国家的官方Instagram账户上的食品营销行为。
Pub Date : 2021-12-21 eCollection Date: 2021-01-01 DOI: 10.1136/bmjnph-2021-000229
Omni Cassidy, Hye Won Shin, Edmund Song, Everett Jiang, Ravindra Harri, Catherine Cano, Rajesh Vedanthan, Gbenga Ogedegbe, Marie Bragg

Background: Social media advertising by fast food companies continues to increase globally, and exposure to food advertising contributes to poor diet and negative health outcomes (eg, cardiovascular disease). McDonald's-the largest fast food company in the world-operates in 101 countries, but little is known about their marketing techniques in various regions. The objective of this study was to compare the social media advertising practices of McDonald's-the largest fast food company in the world-in 15 high-income, upper-middle-income and lower-middle-income countries.

Methods: We randomly selected official McDonald's Instagram accounts for 15 high-income, upper-middle-income and lower-middle-income countries. We captured all the screenshots that McDonald's posted on those Instagram accounts from September to December 2019. We quantified the number of followers, 'likes', 'comments' and video views associated with each account in April 2020. We used content analysis to examine differences in the marketing techniques.

Results: The 15 accounts collectively maintained 10 million followers and generated 3.9 million 'likes', 164 816 comments and 38.2 million video views. We identified 849 posts. The three lower-middle-income countries had more posts (n=324; M, SD=108.0, 38.2 posts) than the five upper-middle-income countries (n=227; M, SD=45.4, 37.5 posts) and seven high-income countries (n=298; M, SD=42.6, 28.2 posts). Approximately 12% of the posts in high-income countries included child-targeted themes compared with 22% in lower-middle-income countries. Fourteen per cent of the posts in high-income countries included price promotions and free giveaways compared with 40% in lower-middle-income countries.

Conclusions: Social media advertising has enabled McDonald's to reach millions of consumers in lower-middle-income and upper-middle-income countries with disproportionately greater child-targeted ads and price promotions in lower-middle-income countries. Such reach is concerning because of the increased risk of diet-related illnesses, including cardiovascular disease, in these regions.

背景:快餐公司的社交媒体广告在全球范围内持续增加,食品广告的曝光导致了不良饮食和负面健康后果(如心血管疾病)。麦当劳是世界上最大的快餐公司,在101个国家开展业务,但人们对其在各个地区的营销技术知之甚少。本研究的目的是比较世界上最大的快餐公司麦当劳在15个高收入、中上收入和中低收入国家的社交媒体广告实践。方法:我们随机选择了15个高收入、中上收入和中低收入国家的麦当劳官方Instagram账户。我们捕捉到了2019年9月至12月麦当劳在这些Instagram账户上发布的所有截图。2020年4月,我们量化了每个账户的关注人数、点赞数、评论数和视频浏览量。我们使用内容分析来检验营销技术的差异。结果:15个账户共维护了10个 万粉丝,产生3.9 百万个“赞”,164 816条评论和38.2条 百万视频浏览量。我们确定了849个职位。三个中等偏下收入国家的职位(n=324;M,SD=108.0,38.2个职位)多于五个中等偏上收入国家(n=227;M,SD=45.4,37.5个职位)和七个高收入国家(n=298;M,SD卡=42.6,28.2个员额)。高收入国家约12%的职位包含针对儿童的主题,而中低收入国家这一比例为22%。高收入国家14%的职位包括价格促销和免费赠品,而中低收入国家这一比例为40%。结论:社交媒体广告使麦当劳能够接触到中低收入和中上收入国家的数百万消费者,在中低收入国家,针对儿童的广告和价格促销不成比例地多。这种影响令人担忧,因为在这些地区,与饮食相关的疾病,包括心血管疾病的风险增加。
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引用次数: 6
期刊
BMJ Nutrition, Prevention and Health
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