Technical Innovations and Patient Support in Radiation Oncology最新文献_第2页

Illuminating the hidden cost: A systematic review of cognitive late effects regarding cancer-related fatigue in treated paediatric brain tumors 揭示隐藏的成本：一项关于治疗的儿童脑肿瘤患者癌症相关疲劳的认知晚期效应的系统综述。

Q1 Nursing

Technical Innovations and Patient Support in Radiation Oncology

Pub Date : 2024-12-09 DOI: 10.1016/j.tipsro.2024.100291

Ingrid Vethe Hernes , Amalie Jansdatter , Anita Nordsteien , Mathilde Haraldsen Normann

Objective

Globally, in 2022, 30,871 children were diagnosed with CNS-tumors. Many have been treated with radiotherapy, and a significant number suffer from chronic late effects, including fatigue. This study aims to investigate previous research on the impact of cancer-related fatigue for neurocognitive function that can be related to radiotherapy in patients who have undergone primary brain radiotherapy before the age of 18.

Methods

Conducted under PRISMA-S framework, this systematic review searched MEDLINE ALL (Ovid), EMBASE (Ovid), CINAHL (EBSCO), and PsycINFO (Ovid) for relevant studies. Criteria for inclusion were children under 18 who underwent radiotherapy for primary brain cancer, focusing on late cognitive side effects, published 2000–2023.

Results

From 4,067 records, 10 studies were included, examining Proton Radiation Therapy (n = 4), X-ray Radiation Therapy (n = 3), and their comparisons (n = 3). The studies used various cognitive tests, and late effects that emerged were neurocognitive functions and disorders, intellectual functioning, specific cognitive functions and daily life, social functioning, and performance. These themes can be encompassed by cancer-related fatigue.

Conclusions

The findings underscore critical need for more in-depth research to understand the health perception variations among children post-primary brain radiotherapy. Furthermore, detailed insights of treatment specifics, disease progression, target volume sizes, and doses to surrounding organs at risk are imperative.

目的：在全球范围内，2022年，30,871名儿童被诊断为中枢神经系统肿瘤。许多人接受了放射治疗，而且相当多的人患有慢性晚期症状，包括疲劳。本研究旨在调查18岁之前接受过初级脑放疗的患者的癌症相关性疲劳对神经认知功能的影响，该影响可能与放疗有关。方法：本系统综述在PRISMA-S框架下，检索MEDLINE ALL （Ovid）、EMBASE （Ovid）、CINAHL （EBSCO）和PsycINFO （Ovid）进行相关研究。纳入标准为18岁以下接受原发性脑癌放疗的儿童，重点关注晚期认知副作用，发表于2000-2023年。结果：从4067份记录中，纳入了10项研究，检查了质子放射治疗（n = 4），x射线放射治疗（n = 3）及其比较（n = 3）。这些研究使用了各种认知测试，出现的后期影响包括神经认知功能和障碍、智力功能、特定认知功能和日常生活、社会功能和表现。这些主题可以被癌症相关的疲劳所涵盖。结论：研究结果强调了对儿童原发性脑放疗后健康感知变化进行更深入研究的迫切需要。此外，详细了解治疗细节、疾病进展、靶体积大小和周围器官的风险剂量是必要的。

{"title":"Illuminating the hidden cost: A systematic review of cognitive late effects regarding cancer-related fatigue in treated paediatric brain tumors","authors":"Ingrid Vethe Hernes , Amalie Jansdatter , Anita Nordsteien , Mathilde Haraldsen Normann","doi":"10.1016/j.tipsro.2024.100291","DOIUrl":"10.1016/j.tipsro.2024.100291","url":null,"abstract":"<div><h3>Objective</h3><div>Globally, in 2022, 30,871 children were diagnosed with CNS-tumors. Many have been treated with radiotherapy, and a significant number suffer from chronic late effects, including fatigue. This study aims to investigate previous research on the impact of cancer-related fatigue for neurocognitive function that can be related to radiotherapy in patients who have undergone primary brain radiotherapy before the age of 18.</div></div><div><h3>Methods</h3><div>Conducted under PRISMA-S framework, this systematic review searched MEDLINE ALL (Ovid), EMBASE (Ovid), CINAHL (EBSCO), and PsycINFO (Ovid) for relevant studies. Criteria for inclusion were children under 18 who underwent radiotherapy for primary brain cancer, focusing on late cognitive side effects, published 2000–2023.</div></div><div><h3>Results</h3><div>From 4,067 records, 10 studies were included, examining Proton Radiation Therapy (n = 4), X-ray Radiation Therapy (n = 3), and their comparisons (n = 3). The studies used various cognitive tests, and late effects that emerged were neurocognitive functions and disorders, intellectual functioning, specific cognitive functions and daily life, social functioning, and performance. These themes can be encompassed by cancer-related fatigue.</div></div><div><h3>Conclusions</h3><div>The findings underscore critical need for more in-depth research to understand the health perception variations among children post-primary brain radiotherapy. Furthermore, detailed insights of treatment specifics, disease progression, target volume sizes, and doses to surrounding organs at risk are imperative.</div></div>","PeriodicalId":36328,"journal":{"name":"Technical Innovations and Patient Support in Radiation Oncology","volume":"33 ","pages":"Article 100291"},"PeriodicalIF":0.0,"publicationDate":"2024-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11699426/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142932896","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Case report: Clinical workflow considerations for treating soft-tissue sarcoma on a 1.5-T MR-Linac

Q1 Nursing

Technical Innovations and Patient Support in Radiation Oncology

Pub Date : 2024-12-07 DOI: 10.1016/j.tipsro.2024.100296

Gye Won Choi, Gary A. Eastwick, Leonard H. Kim

We present specific issues that arose when using a 1.5-Tesla MR-Linac to treat a series of 4 soft-tissue sarcoma (STS) patients. These issues arose from the combination of typical STS attributes (long, off-axis target) and MR-Linac design-specific limitations on field size and patient positioning. Despite the availability of on-line plan adaptation, STS patients were more efficiently treated after workflow changes to improve patient selection and immobilization. Other issues arising from off-axis STS target locations: geometric distortion of MR images and patient-specific QA, are discussed.

引用次数: 0

Advanced practice radiation therapist led vaginal vault brachytherapy: An evaluation of efficiency and effectiveness of service delivery 高级实践放射治疗师引导阴道穹窿近距离治疗：服务交付效率和效果的评估

Q1 Nursing

Technical Innovations and Patient Support in Radiation Oncology

Pub Date : 2024-12-01 DOI: 10.1016/j.tipsro.2024.100289

Rhona Goodwin

Aims

An advanced practice radiation therapist (APRT) role in vaginal vault brachytherapy (VBT) was first introduced in 2015. The aim of this manuscript was to clarify how the introduction of an APRT can improve efficiencies within service delivery while maintaining non inferior clinical outcomes of recurrence.

Materials and methods

This was a single-centred retrospective comparative service evaluation of stage 1 endometrial cancer patients treated with postoperative high dose rate VBT alone. Sixty patients in total were included in the evaluation. They were divided into two equal groups of ‘before’ and ‘after’ based on the introduction of the APRT-led role and changes made to treatment processes. Quantitative analysis of waiting times from surgery to adjuvant VBT (weeks), duration of day one treatment procedure (minutes), rate of isolated vaginal recurrence and loco regional recurrence (vaginal and pelvic) were compared between the groups.

Results

The mean time from surgery to treatment between the ‘before’ and ‘after’ groups was 13.1 and 9.1 weeks respectively. The mean time for day one treatment procedure was 91 min in the ‘before’ group and 59 min in the ‘after’ group. Vaginal free recurrence (VFR) was 100 % for both groups..

Conclusion

An APRT led vaginal vault service, with learnt role extension, allows for a more efficient and effective service delivery.

AimsAn高级实践放射治疗师（APRT）在阴道穹窿近距离治疗（VBT）中的作用于2015年首次推出。本文的目的是阐明APRT的引入如何提高服务提供的效率，同时保持复发的非劣等临床结果。材料和方法本研究是一项单中心回顾性比较服务评估1期子宫内膜癌患者术后单独接受高剂量率VBT治疗。共有60例患者被纳入评估。根据aprt主导作用的引入和治疗过程的变化，他们被分为“之前”和“之后”两组。定量分析从手术到辅助VBT的等待时间（周）、第一天治疗过程的持续时间（分钟）、孤立性阴道复发率和局部区域复发率（阴道和盆腔）。结果术前组和术后组从手术到治疗的平均时间分别为13.1周和9.1周。“治疗前”组治疗第一天的平均时间为91分钟，“治疗后”组为59分钟。结论以APRT为主导的阴道拱顶服务，学习角色的延伸，使服务提供更加高效和有效。

{"title":"Advanced practice radiation therapist led vaginal vault brachytherapy: An evaluation of efficiency and effectiveness of service delivery","authors":"Rhona Goodwin","doi":"10.1016/j.tipsro.2024.100289","DOIUrl":"10.1016/j.tipsro.2024.100289","url":null,"abstract":"<div><h3>Aims</h3><div>An advanced practice radiation therapist (APRT) role in vaginal vault brachytherapy (VBT) was first introduced in 2015. The aim of this manuscript was to clarify how the introduction of an APRT can improve efficiencies within service delivery while maintaining non inferior clinical outcomes of recurrence.</div></div><div><h3>Materials and methods</h3><div>This was a single-centred retrospective comparative service evaluation of stage 1 endometrial cancer patients treated with postoperative high dose rate VBT alone. Sixty patients in total were included in the evaluation. They were divided into two equal groups of ‘before’ and ‘after’ based on the introduction of the APRT-led role and changes made to treatment processes. Quantitative analysis of waiting times from surgery to adjuvant VBT (weeks), duration of day one treatment procedure (minutes), rate of isolated vaginal recurrence and loco regional recurrence (vaginal and pelvic) were compared between the groups.</div></div><div><h3>Results</h3><div>The mean time from surgery to treatment between the ‘before’ and ‘after’ groups was 13.1 and 9.1 weeks respectively. The mean time for day one treatment procedure was 91 min in the ‘before’ group and 59 min in the ‘after’ group. Vaginal free recurrence (VFR) was 100 % for both groups..</div></div><div><h3>Conclusion</h3><div>An APRT led vaginal vault service, with learnt role extension, allows for a more efficient and effective service delivery.</div></div>","PeriodicalId":36328,"journal":{"name":"Technical Innovations and Patient Support in Radiation Oncology","volume":"32 ","pages":"Article 100289"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142743043","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Can Tho oncology (Việt Nam) hospital radiotherapy department: A Snapshot of current and future practice 可拓肿瘤科（Việt南）医院放疗科：当前和未来实践的快照

Q1 Nursing

Technical Innovations and Patient Support in Radiation Oncology

Pub Date : 2024-12-01 DOI: 10.1016/j.tipsro.2024.100292

Tran Thanh Phong, Vo Van Kha, Le Thi Den

Can Tho City Oncology Hospital was established on September 28, 2007, by the People’s Committee of Can Tho City. The Can Tho City Oncology Hospital has been in operation for 17 years and has over time become a reliable place for the provision of oncological patient services and treatment for Can Tho citizens and the Mekong Delta area. The Hospital includes approximately 400 patient beds, 9 clinical departments, 5 paraclinical departments (radiology, pathology etc), and 8 functional rooms (customer care epartment, admissions, discharge office, finance and accounting division,). The Radiotherapy Department is a busy and important part of the Hospital and plays an important role in cancer patient treatment.

Introducing the current situation, challenges and future plans for the Radiotherapy Department in Can Tho Oncology Hospital, Việt Nam.

芹苴市肿瘤医院由芹苴市人民委员会于2007年9月28日成立。芹苴市肿瘤医院已经运营了17年，随着时间的推移，它已成为为芹苴市民和湄公河三角洲地区提供肿瘤患者服务和治疗的可靠场所。医院拥有近400张病床，9个临床科室，5个临床辅助科室（放射科、病理科等），8个功能室（客户服务部、入院、出院处、财务科、）。放疗科是医院的一个繁忙而重要的组成部分，在肿瘤患者的治疗中起着重要的作用。介绍灿苴肿瘤医院放射治疗科的现况、挑战及未来计划Việt南。

引用次数: 0

Benchmarking and performance evaluation of a novel deformable image registration software for radiotherapy CT images 一种用于放疗CT图像的新型可变形图像配准软件的基准测试和性能评估。

Q1 Nursing

Technical Innovations and Patient Support in Radiation Oncology

Pub Date : 2024-12-01 DOI: 10.1016/j.tipsro.2024.100295

Shorug S. Alshammari , Sridhar Yaddanapudi , Blaž Kušnik , Rok Ivančič , Kristjan Anderle , Jonathan G. Li , Keith M. Furutani , Chris J. Beltran , Bo Lu

Purpose

We evaluated and benchmarked a novel deformable image registration (DIR) software functionality (DirOne, Cosylab d.d., Ljubljana, Slovenia) by comparing it to two commercial systems, MIM and VelocityAI, following AAPM task group 132 (TG-132) guidelines.

Methods

Three publicly available datasets were used for evaluation. The first dataset includes primary and deformed phantom images for a male pelvis. The second, from DIR-Lab, contains ten sets of 4D CT thoracic scans. The third dataset, from the DIR Evaluation Project (DIREP), includes ten head and neck CTs. VelocityAI and MIM served as benchmarks to assess DirOne’s performance. Target registration error (TRE), dice similarity coefficient (DSC), and mean distance to agreement (MDA) were the evaluation metrics.

Results

For TRE, the average results for DirOne, MIM, and VelocityAI were 3.3 ± 3.1 mm, 2.7 ± 3.7 mm, and 3.4 ± 2.4 mm, respectively. For DSC, DirOne achieved 0.96 ± 0.02, MIM 0.98 ± 0.02, and VelocityAI 0.98 ± 0.01 across the first and second datasets. In the DIREP dataset, DirOne achieved 0.73 ± 0.34 for MDA and 0.91 ± 0.03 for DSC; MIM achieved 0.54 ± 0.36 and 0.93 ± 0.02, and VelocityAI 0.93 ± 0.38 and 0.90 ± 0.03.

Conclusion

The novel DIR software demonstrated clinically acceptable accuracy compared to other commercial systems, supporting its potential use in radiotherapy treatment planning applications such as automatic image segmentation, 4D segmentation propagation, and dose warping.

目的：我们根据AAPM任务组132 （TG-132）指南，将一种新的可变形图像配准（DIR）软件功能（DirOne， Cosylab博士，卢布尔雅那，斯洛文尼亚）与两个商业系统MIM和VelocityAI进行比较，评估并对其进行基准测试。方法：使用三个公开可用的数据集进行评估。第一个数据集包括男性骨盆的原始和变形幻象图像。第二份来自DIR-Lab，包含十组4D CT胸部扫描。第三个数据集来自DIR评估项目（DIREP），包括10个头颈部ct。VelocityAI和MIM作为评估DirOne性能的基准。目标配准误差（TRE）、骰子相似系数（DSC）和平均一致距离（MDA）为评价指标。结果：对于TRE， DirOne、MIM和VelocityAI的平均结果分别为3.3±3.1 mm、2.7±3.7 mm和3.4±2.4 mm。对于DSC， DirOne在第一和第二数据集上实现了0.96±0.02，MIM为0.98±0.02，VelocityAI为0.98±0.01。在DIREP数据集中，DirOne的MDA和DSC分别达到0.73±0.34和0.91±0.03；MIM分别为0.54±0.36和0.93±0.02，VelocityAI分别为0.93±0.38和0.90±0.03。结论：与其他商业系统相比，新型DIR软件具有临床可接受的准确性，支持其在放射治疗计划应用中的潜在应用，如自动图像分割，4D分割传播和剂量翘曲。

{"title":"Benchmarking and performance evaluation of a novel deformable image registration software for radiotherapy CT images","authors":"Shorug S. Alshammari , Sridhar Yaddanapudi , Blaž Kušnik , Rok Ivančič , Kristjan Anderle , Jonathan G. Li , Keith M. Furutani , Chris J. Beltran , Bo Lu","doi":"10.1016/j.tipsro.2024.100295","DOIUrl":"10.1016/j.tipsro.2024.100295","url":null,"abstract":"<div><h3>Purpose</h3><div>We evaluated and benchmarked a novel deformable image registration (DIR) software functionality (DirOne, Cosylab d.d., Ljubljana, Slovenia) by comparing it to two commercial systems, MIM and VelocityAI, following AAPM task group 132 (TG-132) guidelines.</div></div><div><h3>Methods</h3><div>Three publicly available datasets were used for evaluation. The first dataset includes primary and deformed phantom images for a male pelvis. The second, from DIR-Lab, contains ten sets of 4D CT thoracic scans. The third dataset, from the DIR Evaluation Project (DIREP), includes ten head and neck CTs. VelocityAI and MIM served as benchmarks to assess DirOne’s performance. Target registration error (TRE), dice similarity coefficient (DSC), and mean distance to agreement (MDA) were the evaluation metrics.</div></div><div><h3>Results</h3><div>For TRE, the average results for DirOne, MIM, and VelocityAI were 3.3 ± 3.1 mm, 2.7 ± 3.7 mm, and 3.4 ± 2.4 mm, respectively. For DSC, DirOne achieved 0.96 ± 0.02, MIM 0.98 ± 0.02, and VelocityAI 0.98 ± 0.01 across the first and second datasets. In the DIREP dataset, DirOne achieved 0.73 ± 0.34 for MDA and 0.91 ± 0.03 for DSC; MIM achieved 0.54 ± 0.36 and 0.93 ± 0.02, and VelocityAI 0.93 ± 0.38 and 0.90 ± 0.03.</div></div><div><h3>Conclusion</h3><div>The novel DIR software demonstrated clinically acceptable accuracy compared to other commercial systems, supporting its potential use in radiotherapy treatment planning applications such as automatic image segmentation, 4D segmentation propagation, and dose warping.</div></div>","PeriodicalId":36328,"journal":{"name":"Technical Innovations and Patient Support in Radiation Oncology","volume":"32 ","pages":"Article 100295"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11665300/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142883117","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparison of predicted and actual dermatitis generated from computed tomography images and dose distribution maps 计算机断层扫描图像和剂量分布图生成的预测皮炎与实际皮炎的比较

Q1 Nursing

Technical Innovations and Patient Support in Radiation Oncology

Pub Date : 2024-11-22 DOI: 10.1016/j.tipsro.2024.100294

Yasuhide Miyabe , Saori Oshiro , Hiroto Seki , Yusuke Muroi , Eriko Kawashima , Megumi Hosoda , Kento Ohashi , Hiromu Yamanaka , Mingliang Shao , Hiromi Sugawara , Jyunetsu Mizoe , Ritsuko Komaki

Anticipating the onset, location and severity of radiation dermatitis before radiotherapy can aid in dermatological care. This study developed a method for creation of a prediction diagram for dermatitis and conducted a comparative verification between the prediction diagram and actual patient condition. The prediction diagram involved converting skin doses into 2 Gy fractionated equivalent doses using α/β of 10.0, defining regions of interest (ROIs) from 20-50 Gy at 10 Gy intervals. Overlaps between these ROIs at each dose level and the skin (external) was sequentially color-coded as blue, yellow, red, and purple. The study included four patients: two underwent head and neck treatment and two received neck and chest treatment. This approach involved a visual assessment comparing the prediction diagram with skin photographs captured at the end of treatment. Nurses marked skin sites corresponding to grades 1 and 2 on photographs, assessing their correlation with the predicted range. Visual assessment results were largely positive, although one patient exhibited slightly lower scores. Results revealed a correlation between grade 1 skin reactions and the 20 Gy regions. Grade 2 reactions were observed in regions near 30 and 40 Gy. Although discrepancies between prediction diagram and actual skin symptoms were observed in patients, a broad agreement was evident. The prediction diagram cannot accurately predict radiation dermatitis, as it does not account for skin symptoms unrelated to the dose. However, the diagram is significant as it provides physicians, nurses, and patients with concise and visually comprehensible information regarding the location of dermatitis.

在放疗前预测放射性皮炎的发病时间、部位和严重程度有助于皮肤病护理。本研究开发了一种创建皮炎预测图的方法，并对预测图和患者实际情况进行了对比验证。预测图包括使用 10.0 α/β 将皮肤剂量转换为 2 Gy 分馏当量剂量，以 10 Gy 为间隔定义 20-50 Gy 的感兴趣区 (ROI)。每个剂量水平的这些 ROI 与皮肤（外部）之间的重叠区域依次用蓝色、黄色、红色和紫色标示。这项研究包括四名患者：两名接受头颈部治疗，两名接受颈部和胸部治疗。这种方法包括将预测图与治疗结束时拍摄的皮肤照片进行比较的视觉评估。护士在照片上标出与 1 级和 2 级相对应的皮肤部位，评估它们与预测范围的相关性。目测评估结果基本上是正面的，但有一名患者的得分略低。结果显示，1 级皮肤反应与 20 Gy 区域相关。在接近 30 Gy 和 40 Gy 的区域观察到 2 级反应。虽然在患者身上观察到的预测图与实际皮肤症状之间存在差异，但两者之间的一致性非常明显。预测图无法准确预测放射性皮炎，因为它没有考虑到与剂量无关的皮肤症状。不过，预测图为医生、护士和患者提供了有关皮炎发生部位的简明、直观的信息，因此意义重大。

{"title":"Comparison of predicted and actual dermatitis generated from computed tomography images and dose distribution maps","authors":"Yasuhide Miyabe , Saori Oshiro , Hiroto Seki , Yusuke Muroi , Eriko Kawashima , Megumi Hosoda , Kento Ohashi , Hiromu Yamanaka , Mingliang Shao , Hiromi Sugawara , Jyunetsu Mizoe , Ritsuko Komaki","doi":"10.1016/j.tipsro.2024.100294","DOIUrl":"10.1016/j.tipsro.2024.100294","url":null,"abstract":"<div><div>Anticipating the onset, location and severity of radiation dermatitis before radiotherapy can aid in dermatological care. This study developed a method for creation of a prediction diagram for dermatitis and conducted a comparative verification between the prediction diagram and actual patient condition. The prediction diagram involved converting skin doses into 2 Gy fractionated equivalent doses using α/β of 10.0, defining regions of interest (ROIs) from 20-50 Gy at 10 Gy intervals. Overlaps between these ROIs at each dose level and the skin (external) was sequentially color-coded as blue, yellow, red, and purple. The study included four patients: two underwent head and neck treatment and two received neck and chest treatment. This approach involved a visual assessment comparing the prediction diagram with skin photographs captured at the end of treatment. Nurses marked skin sites corresponding to grades 1 and 2 on photographs, assessing their correlation with the predicted range. Visual assessment results were largely positive, although one patient exhibited slightly lower scores. Results revealed a correlation between grade 1 skin reactions and the 20 Gy regions. Grade 2 reactions were observed in regions near 30 and 40 Gy. Although discrepancies between prediction diagram and actual skin symptoms were observed in patients, a broad agreement was evident. The prediction diagram cannot accurately predict radiation dermatitis, as it does not account for skin symptoms unrelated to the dose. However, the diagram is significant as it provides physicians, nurses, and patients with concise and visually comprehensible information regarding the location of dermatitis.</div></div>","PeriodicalId":36328,"journal":{"name":"Technical Innovations and Patient Support in Radiation Oncology","volume":"32 ","pages":"Article 100294"},"PeriodicalIF":0.0,"publicationDate":"2024-11-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142722428","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Developing a modern radiotherapy department in a rural hospital in Cameroon: The Mbingo experience 在喀麦隆一家乡村医院建立现代化放射治疗科：姆宾戈的经验

Q1 Nursing

Technical Innovations and Patient Support in Radiation Oncology

Pub Date : 2024-11-17 DOI: 10.1016/j.tipsro.2024.100293

Ntumsi Akundoh Tontu , William W.Y. Cheung , Marcus Jones , Linda Grossheim , Dennis Palmer , Earnest Chukwudi N. Okonkwo , Eric Moore , Keith Streatfield , Laurie Elit

Although radiotherapy is critical for cancer cure and palliation, access to such expensive and sophisticated technology is very limited in low- and middle-income countries (LMIC). Cancer incidence in Africa is currently 1.5 million case per year, thus urgent and innovative solutions are required to build necessary infrastructure needed to address this global health challenge. We describe our approach and challenges as a faith based non-government organization in setting up a modern radiotherapy department in a rural hospital in Cameroon to mitigate this unmet need. We highlite our engagement with international bodies and individuals for fund raising and volunteerism, local radiotherapy workforce development and training (radiation oncology, dosimetrists, radiation therapist and medical physicists) and the expertise required for construction of the bunker and installation of the Linac machine.

尽管放射治疗对癌症的治愈和缓解至关重要，但在中低收入国家（LMIC），获得这种昂贵而先进技术的机会非常有限。目前，非洲的癌症发病率为每年 150 万例，因此需要迫切的创新解决方案来建设必要的基础设施，以应对这一全球健康挑战。我们介绍了作为一个以信仰为基础的非政府组织，我们在喀麦隆的一家农村医院建立现代化放射治疗部门的方法和面临的挑战，以缓解这一尚未得到满足的需求。我们重点介绍了我们与国际机构和个人合作筹集资金和开展志愿服务的情况、当地放射治疗人员队伍的发展和培训情况（肿瘤放射治疗、剂量测量师、放射治疗师和医学物理学家），以及建造掩体和安装直列加速器所需的专业知识。

引用次数: 0

The clinical application of in vivo dosimetry for gynaecological brachytherapy: A scoping review 体内剂量法在妇科近距离放射治疗中的临床应用综述。

Q1 Nursing

Technical Innovations and Patient Support in Radiation Oncology

Pub Date : 2024-11-16 DOI: 10.1016/j.tipsro.2024.100290

Amani A. Chowdhury , Steve Bolton , Gerry Lowe , Eliana Vasquez Osorio , William Hamblyn , Peter J Hoskin

Brachytherapy is a key treatment for gynaecological malignancies, delivering high doses to the tumour volume whilst sparing nearby normal tissues due to its steep dose gradient. Accuracy is imperative as small shifts can lead to clinically significant under- or over-dosing of the target volume or organs at risk (OARs), respectively. Independent verification of dose delivered during brachytherapy is not routinely performed but it is important to identify gross errors and define action thresholds to guide inter-fraction treatment decisions. In vivo dosimetry (IVD) is one strategy for improving accuracy and identifying potential errors. Despite promising phantom work, clinical application of IVD is lacking. A literature search was performed using Medline and EMBASE without date limits and based on the PICO framework to evaluate the clinical application of IVD in gynaecological brachytherapy. After screening of titles and abstracts, full text papers were reviewed and 28 studies were identified. Several dosimeters were utilised and measurements were typically taken from the rectum, bladder, vagina and within interstitial catheters. Significant differences between calculated and measured dose were attributed to geometric shifts. The studies reviewed demonstrated the feasibility of IVD in brachytherapy for dose verification but further work is required before IVD can be used to optimise treatment. The purpose of this scoping review is to investigate the clinical application of IVD in gynaecological brachytherapy, understand its challenges and identify the steps required to facilitate integration into everyday clinical practice.

近距离放射治疗是妇科恶性肿瘤的关键治疗方法，由于其陡峭的剂量梯度，它向肿瘤体积提供高剂量，同时保留附近的正常组织。准确性是至关重要的，因为微小的变化分别会导致靶体积或危险器官（OARs）的临床显著剂量不足或过量。对近距离治疗期间剂量的独立验证通常不进行，但重要的是确定严重误差和确定行动阈值，以指导分段间治疗决策。体内剂量法（IVD）是提高准确性和识别潜在错误的一种策略。尽管有前景的幻影工作，临床应用IVD缺乏。使用Medline和EMBASE进行文献检索，无日期限制，基于PICO框架评估IVD在妇科近距离放疗中的临床应用。在对题目和摘要进行筛选后，对全文论文进行了审查，并确定了28项研究。使用了几种剂量计，通常从直肠、膀胱、阴道和间质导管内进行测量。计算剂量和测量剂量之间的显著差异归因于几何位移。所回顾的研究表明，IVD在近距离放射治疗中用于剂量验证的可行性，但在IVD用于优化治疗之前，还需要进一步的工作。本综述的目的是调查IVD在妇科近距离放射治疗中的临床应用，了解其面临的挑战，并确定将其融入日常临床实践所需的步骤。

{"title":"The clinical application of in vivo dosimetry for gynaecological brachytherapy: A scoping review","authors":"Amani A. Chowdhury , Steve Bolton , Gerry Lowe , Eliana Vasquez Osorio , William Hamblyn , Peter J Hoskin","doi":"10.1016/j.tipsro.2024.100290","DOIUrl":"10.1016/j.tipsro.2024.100290","url":null,"abstract":"<div><div>Brachytherapy is a key treatment for gynaecological malignancies, delivering high doses to the tumour volume whilst sparing nearby normal tissues due to its steep dose gradient. Accuracy is imperative as small shifts can lead to clinically significant under- or over-dosing of the target volume or organs at risk (OARs), respectively. Independent verification of dose delivered during brachytherapy is not routinely performed but it is important to identify gross errors and define action thresholds to guide inter-fraction treatment decisions. In vivo dosimetry (IVD) is one strategy for improving accuracy and identifying potential errors. Despite promising phantom work, clinical application of IVD is lacking. A literature search was performed using Medline and EMBASE without date limits and based on the PICO framework to evaluate the clinical application of IVD in gynaecological brachytherapy. After screening of titles and abstracts, full text papers were reviewed and 28 studies were identified. Several dosimeters were utilised and measurements were typically taken from the rectum, bladder, vagina and within interstitial catheters. Significant differences between calculated and measured dose were attributed to geometric shifts. The studies reviewed demonstrated the feasibility of IVD in brachytherapy for dose verification but further work is required before IVD can be used to optimise treatment. The purpose of this scoping review is to investigate the clinical application of IVD in gynaecological brachytherapy, understand its challenges and identify the steps required to facilitate integration into everyday clinical practice.</div></div>","PeriodicalId":36328,"journal":{"name":"Technical Innovations and Patient Support in Radiation Oncology","volume":"33 ","pages":"Article 100290"},"PeriodicalIF":0.0,"publicationDate":"2024-11-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11718348/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142972447","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The status quo of global geriatric radiation oncology education: A scoping review 全球老年放射肿瘤学教育的现状：范围审查

Q1 Nursing

Technical Innovations and Patient Support in Radiation Oncology

Pub Date : 2024-11-10 DOI: 10.1016/j.tipsro.2024.100288

Lucinda Morris , Sandra Turner , Jane L. Phillips , Anamika Parmar , Meera Agar

Purpose

To identify potential gaps in geriatric radiation oncology (RO) education worldwide, as measured by geriatric oncology (GO) content within postgraduate RO training program (TP) curricula across 8 focus countries.

Methods and materials

The need for improved education around GO is internationally recognized and is a key strategic priority of the International Society of Geriatric Oncology (SIOG).

Two reviewers undertook a systematic scoping review from March to September 2023. Focus countries were selected using predefined selection criteria based on national radiation therapy (RT) service provision, RT access and post-graduate specialty training standards. This review is in accordance with evidence-based curriculum design methodology and represents the initial phase i.e., problem identification and needs assessment.

Results

Overall RO TP and curriculum elements varied by jurisdiction. Common elements included length of training, summative assessments and prerequisite requirements. Considerable variability exists across TPs around identified learning outcomes, content, TP organization, training networks and accreditation.

Across 6 TPs, only 2 had any documented GO curriculum content. Of these, only one contained geriatric RO content scoring moderate to high based on accepted quality benchmarks. Outside official RO TPs, there is considerable GO online education content, including face to face courses, peer-reviewed articles, learning materials and resources relevant to RO postgraduate training worldwide. However accessibility to these learning interventions may be region specific and content is not standardized.

Conclusions

As expected, this systematic scoping review has identified significant gaps in GO education within RO TPs worldwide. These findings represent an essential step in the development of evidence-based recommendations for updating standards for GO training within RO training programs and establishing a globally accepted, standardized benchmarks for minimal geriatric RO education. In turn, this will ensure future radiation oncologists are able to deliver a high standard of care to and improve outcomes for older people with cancer.

目的根据8个重点国家的放射肿瘤学研究生培训计划（TP）课程中的老年肿瘤学（GO）内容，确定全球老年放射肿瘤学（RO）教育的潜在差距。方法和材料围绕老年肿瘤学改进教育的必要性已得到国际公认，并且是国际老年肿瘤学会（SIOG）的一项关键战略重点。根据国家放射治疗（RT）服务提供情况、放射治疗普及率和研究生专业培训标准，采用预定义的选择标准选定了重点国家。本次审查符合循证课程设计方法，是问题识别和需求评估的初始阶段。共同要素包括培训时间、终结性评估和前提要求。在 6 个培训方案中，只有 2 个有记录的全球老年医学课程内容。在 6 个培训课程中，只有 2 个有记录的 GO 课程内容，其中只有一个包含老年 RO 内容，根据公认的质量基准，得分在中等到高等之间。在官方的 RO 培训课程之外，还有大量的 GO 在线教育内容，包括面对面课程、同行评审文章、学习材料以及与全球 RO 研究生培训相关的资源。然而，这些学习干预措施的可及性可能因地区而异，而且内容也没有标准化。这些发现代表了在制定循证建议方面迈出的重要一步，这些建议旨在更新区域放射治疗培训计划中的全球放射治疗培训标准，并为最低限度的老年区域放射治疗教育建立全球公认的标准化基准。反过来，这将确保未来的放射肿瘤学家能够为老年癌症患者提供高标准的治疗，并改善治疗效果。

{"title":"The status quo of global geriatric radiation oncology education: A scoping review","authors":"Lucinda Morris , Sandra Turner , Jane L. Phillips , Anamika Parmar , Meera Agar","doi":"10.1016/j.tipsro.2024.100288","DOIUrl":"10.1016/j.tipsro.2024.100288","url":null,"abstract":"<div><h3>Purpose</h3><div>To identify potential gaps in geriatric radiation oncology (RO) education worldwide, as measured by geriatric oncology (GO) content within postgraduate RO training program (TP) curricula across 8 focus countries.</div></div><div><h3>Methods and materials</h3><div>The need for improved education around GO is internationally recognized and is a key strategic priority of the International Society of Geriatric Oncology (SIOG).</div><div>Two reviewers undertook a systematic scoping review from March to September 2023. Focus countries were selected using predefined selection criteria based on national radiation therapy (RT) service provision, RT access and post-graduate specialty training standards. This review is in accordance with evidence-based curriculum design methodology and represents the initial phase i.e., problem identification and needs assessment.</div></div><div><h3>Results</h3><div>Overall RO TP and curriculum elements varied by jurisdiction. Common elements included length of training, summative assessments and prerequisite requirements. Considerable variability exists across TPs around identified learning outcomes, content, TP organization, training networks and accreditation.</div><div>Across 6 TPs, only 2 had any documented GO curriculum content. Of these, only one contained geriatric RO content scoring moderate to high based on accepted quality benchmarks. Outside official RO TPs, there is considerable GO online education content, including face to face courses, peer-reviewed articles, learning materials and resources relevant to RO postgraduate training worldwide. However accessibility to these learning interventions may be region specific and content is not standardized.</div></div><div><h3>Conclusions</h3><div>As expected, this systematic scoping review has identified significant gaps in GO education within RO TPs worldwide. These findings represent an essential step in the development of evidence-based recommendations for updating standards for GO training within RO training programs and establishing a globally accepted, standardized benchmarks for minimal geriatric RO education. In turn, this will ensure future radiation oncologists are able to deliver a high standard of care to and improve outcomes for older people with cancer.</div></div>","PeriodicalId":36328,"journal":{"name":"Technical Innovations and Patient Support in Radiation Oncology","volume":"32 ","pages":"Article 100288"},"PeriodicalIF":0.0,"publicationDate":"2024-11-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142657275","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A systematic review of prostate bed motion and anisotropic margins in post-prostatectomy external beam radiotherapy 前列腺切除术后体外放射治疗中前列腺床运动和各向异性边缘的系统性综述

Q1 Nursing

Technical Innovations and Patient Support in Radiation Oncology

Pub Date : 2024-10-29 DOI: 10.1016/j.tipsro.2024.100287

T. Hodgins, E. Forde

Background

Prostate bed (PB) motion may lead to geographical miss of the target volume in post-prostatectomy radiotherapy (RT). Optimal clinical target volume (CTV) to planning target volume (PTV) margins prevent geographical miss and unnecessary irradiation of normal tissue. There is little data available informing appropriate CTV to PTV margins in the post-prostatectomy setting. The purpose of this review was to quantify the inter-fraction and intra-fraction motion of the PB and draw a conclusion regarding the use of anisotropic CTV to PTV margins for post-prostatectomy RT treatment.

Methodology

A search of PubMed and EMBASE databases was carried out using keywords (prostate bed [Title/Abstract]) AND (motion [Title/Abstract]). All study types assessing inter-fraction and/or intra-fraction motion of the PB based on imaging of soft tissue anatomy were included. Data on patient preparation, immobilisation, and image guidance was abstracted from the included studies. Magnitude of PB motion along with the estimated CTV to PTV margins calculated was also tabulated. Quality of studies was assessed using the MINORS tool.

Results

Seventeen studies were included in the analysis. The largest magnitude of inter-fraction PB motion occurs in the anterior-posterior direction. This motion is attributed to the influence of the bladder and rectal volume on the PB. The PB moves independently of bone and the magnitude of motion varies between the superior and inferior portions of the prostate bed.

Conclusion

Anisotropic CTV to PTV margins are appropriate for use in the post-prostatectomy setting and their implementation for treatment planning purposes are warranted based on the evidence reviewed.

背景前列腺床（PB）的移动可能会导致前列腺切除术后放疗（RT）靶体积的地理遗漏。最佳的临床靶体积（CTV）与计划靶体积（PTV）边缘可防止地理漏诊和对正常组织的不必要照射。关于前列腺切除术后适当的 CTV 至 PTV 边界，目前可用的数据很少。本综述旨在量化前列腺床的分段间和分段内运动，并就前列腺切除术后 RT 治疗中使用各向异性的 CTV 至 PTV 边界得出结论。所有基于软组织解剖学成像评估前列腺腺床分段间和/或分段内运动的研究类型均被纳入其中。从纳入的研究中抽取有关患者准备、固定和图像引导的数据。PB 运动的幅度以及计算出的估计 CTV 到 PTV 边界也被制成表格。研究质量采用 MINORS 工具进行评估。在前后方向上，分段间 PB 运动的幅度最大。这种运动归因于膀胱和直肠容积对 PB 的影响。结论各向异性的 CTV 至 PTV 边界适合用于前列腺切除术后的治疗，根据所回顾的证据，有必要将其用于治疗规划。

{"title":"A systematic review of prostate bed motion and anisotropic margins in post-prostatectomy external beam radiotherapy","authors":"T. Hodgins, E. Forde","doi":"10.1016/j.tipsro.2024.100287","DOIUrl":"10.1016/j.tipsro.2024.100287","url":null,"abstract":"<div><h3>Background</h3><div>Prostate bed (PB) motion may lead to geographical miss of the target volume in post-prostatectomy radiotherapy (RT). Optimal clinical target volume (CTV) to planning target volume (PTV) margins prevent geographical miss and unnecessary irradiation of normal tissue. There is little data available informing appropriate CTV to PTV margins in the post-prostatectomy setting. The purpose of this review was to quantify the inter-fraction and intra-fraction motion of the PB and draw a conclusion regarding the use of anisotropic CTV to PTV margins for post-prostatectomy RT treatment.</div></div><div><h3>Methodology</h3><div>A search of PubMed and EMBASE databases was carried out using keywords (prostate bed [Title/Abstract]) AND (motion [Title/Abstract]). All study types assessing inter-fraction and/or intra-fraction motion of the PB based on imaging of soft tissue anatomy were included. Data on patient preparation, immobilisation, and image guidance was abstracted from the included studies. Magnitude of PB motion along with the estimated CTV to PTV margins calculated was also tabulated. Quality of studies was assessed using the MINORS tool.</div></div><div><h3>Results</h3><div>Seventeen studies were included in the analysis. The largest magnitude of inter-fraction PB motion occurs in the anterior-posterior direction. This motion is attributed to the influence of the bladder and rectal volume on the PB. The PB moves independently of bone and the magnitude of motion varies between the superior and inferior portions of the prostate bed.</div></div><div><h3>Conclusion</h3><div>Anisotropic CTV to PTV margins are appropriate for use in the post-prostatectomy setting and their implementation for treatment planning purposes are warranted based on the evidence reviewed.</div></div>","PeriodicalId":36328,"journal":{"name":"Technical Innovations and Patient Support in Radiation Oncology","volume":"32 ","pages":"Article 100287"},"PeriodicalIF":0.0,"publicationDate":"2024-10-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142572526","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0