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The HoPE Model Architecture: a Novel Approach to Pregnancy Information Retrieval Based on Conversational Agents HoPE模型体系结构:一种基于会话Agent的妊娠信息检索新方法
IF 5.9 Q1 Computer Science Pub Date : 2022-04-06 DOI: 10.1007/s41666-022-00115-0
João Luis Zeni Montenegro, C. A. da Costa
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引用次数: 2
Informative Causality Extraction from Medical Literature via Dependency-Tree–Based Patterns 基于依赖树模式的医学文献信息因果关系提取
IF 5.9 Q1 Computer Science Pub Date : 2022-03-13 DOI: 10.1007/s41666-022-00116-z
Md. Ahsanul Kabir, Aljohara Almulhim, Xiao Luo, M. Hasan
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引用次数: 2
Context-Aware Probabilistic Models for Predicting Future Sedentary Behaviors of Smartphone Users. 预测智能手机用户未来久坐行为的情境感知概率模型。
IF 5.9 Q1 Computer Science Pub Date : 2022-03-01 DOI: 10.1007/s41666-021-00107-6
Qian He, Emmanuel O Agu

Sedentary behaviors are now prevalent as most modern jobs are done while seated. However, such sedentary behaviors have been found to increase the risk of several ailments including diabetes, cardiovascular disease, and all-cause mortality. Current interventions are mostly reactive and are triggered after the user has already been sedentary. Behavior change theory suggests that preventive sedentary interventions, which are triggered before a person becomes sedentary, are more likely to succeed. In this paper, we characterize user patterns of sedentary behaviors by analyzing smartphone-sensor data in a real-world dataset. Our work reveals location types (where), times of day/week (when), and smartphone contexts in which sedentary behaviors are most likely. Leveraging our findings, we then propose a set of context-aware probabilistic models that can predict sedentary behaviors in advance by analyzing smartphone sensor data. Our Context-Aware Predictive (CAP) models leverage smartphone-sensed contextual variables and the user's history of sedentary behaviors to predict their future sedentary behaviors. We rigorously analyze the performance of our models and discuss the implications of our work.

久坐行为现在很普遍,因为大多数现代工作都是坐着完成的。然而,人们发现这种久坐不动的行为会增加几种疾病的风险,包括糖尿病、心血管疾病和全因死亡率。目前的干预大多是反应性的,是在用户已经久坐之后触发的。行为改变理论认为,在一个人变得久坐不动之前进行预防性久坐干预,更有可能成功。在本文中,我们通过分析现实世界数据集中的智能手机传感器数据来表征用户久坐行为的模式。我们的研究揭示了最可能发生久坐行为的地点类型(地点)、一天/一周的时间(时间)和智能手机环境。利用我们的发现,我们提出了一套情景感知概率模型,可以通过分析智能手机传感器数据提前预测久坐行为。我们的情境感知预测(CAP)模型利用智能手机感知的情境变量和用户久坐行为的历史来预测他们未来的久坐行为。我们严格地分析了我们模型的性能,并讨论了我们工作的含义。
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引用次数: 2
Managing Boundary Uncertainty in Diagnosing the Patients of Rural Area Using Fuzzy and Rough Set. 模糊与粗糙集在农村病人诊断中的边界不确定性管理。
IF 5.9 Q1 Computer Science Pub Date : 2022-03-01 DOI: 10.1007/s41666-021-00109-4
Sayan Das, Jaya Sil

People of rural India often suffer from acute health conditions like diarrhea, flu, lung congestion, and anemia, but they are not receiving treatment even at primary level due to scarcity of doctors and health infrastructure in remote villages. Health workers are involved in diagnosing the patients based on the symptoms and physiological signs. However, due to inadequate domain knowledge, lack of expertise, and error in measuring the health data, uncertainty creeps in the decision space, resulting many false cases in predicting the diseases. The paper proposes an uncertainty management technique using fuzzy and rough set theory to diagnose the patients with minimum false-positive and false-negative cases. We use fuzzy variables with proper semantic to represent the vagueness of input data, appearing due to measurement error. We derive initial degree of belonging of each patient in two different disease class labels (YES/NO) using the fuzzified input data. Next, we apply rough set theory to manage uncertainty in diagnosing the diseases by learning approximations of the decision boundary between the two class labels. The optimum lower and upper approximation membership functions for each disease class label have been obtained using Non-dominated Sorting Genetic Algorithm-II (NSGA-II). Finally, using the proposed disease_similarity_factor, new patients are diagnosed precisely with 98% accuracy and minimum false cases.

印度农村的人经常患有腹泻、流感、肺充血和贫血等急性疾病,但由于偏远村庄医生和卫生基础设施匮乏,他们甚至没有得到初级治疗。卫生工作者根据症状和生理体征参与对患者的诊断。然而,由于领域知识不足,缺乏专业知识,以及在测量健康数据时存在错误,不确定性在决策空间中蔓延,导致许多疾病预测的错误案例。本文提出了一种利用模糊和粗糙集理论的不确定性管理技术来诊断假阳性和假阴性病例最少的患者。我们使用具有适当语义的模糊变量来表示由于测量误差而出现的输入数据的模糊性。我们使用模糊化的输入数据导出每个患者在两种不同疾病类别标签(YES/NO)中的初始归属程度。接下来,我们应用粗糙集理论通过学习两个类标签之间的决策边界的近似来管理疾病诊断中的不确定性。利用非支配排序遗传算法- ii (NSGA-II)获得了每个疾病分类标签的最优上下近似隶属度函数。最后,利用提出的疾病相似度因子,新患者的诊断准确率达到98%,假病例最少。
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引用次数: 0
COVID-19 Pandemic: Identifying Key Issues Using Social Media and Natural Language Processing. COVID-19大流行:使用社交媒体和自然语言处理识别关键问题。
IF 5.9 Q1 Computer Science Pub Date : 2022-02-11 eCollection Date: 2022-06-01 DOI: 10.1007/s41666-021-00111-w
Oladapo Oyebode, Chinenye Ndulue, Dinesh Mulchandani, Banuchitra Suruliraj, Ashfaq Adib, Fidelia Anulika Orji, Evangelos Milios, Stan Matwin, Rita Orji

The COVID-19 pandemic has affected people's lives in many ways. Social media data can reveal public perceptions and experience with respect to the pandemic, and also reveal factors that hamper or support efforts to curb global spread of the disease. In this paper, we analyzed COVID-19-related comments collected from six social media platforms using natural language processing (NLP) techniques. We identified relevant opinionated keyphrases and their respective sentiment polarity (negative or positive) from over 1 million randomly selected comments, and then categorized them into broader themes using thematic analysis. Our results uncover 34 negative themes out of which 17 are economic, socio-political, educational, and political issues. Twenty (20) positive themes were also identified. We discuss the negative issues and suggest interventions to tackle them based on the positive themes and research evidence.

新冠肺炎大流行在许多方面影响了人们的生活。社交媒体数据可以揭示公众对疫情的看法和经历,也可以揭示阻碍或支持遏制疾病全球传播的因素。在本文中,我们使用自然语言处理(NLP)技术分析了从六个社交媒体平台收集的与COVID-19相关的评论。我们从100多万条随机选择的评论中确定了相关的固执己见的关键短语及其各自的情绪极性(消极或积极),然后使用主题分析将其归类为更广泛的主题。我们的研究结果揭示了34个负面主题,其中17个是经济、社会政治、教育和政治问题。还确定了二十(20)个积极主题。我们讨论了负面问题,并根据积极的主题和研究证据提出了解决这些问题的干预措施。
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引用次数: 16
Explainable Artificial Intelligence for Predictive Modeling in Healthcare. 用于医疗保健预测建模的可解释人工智能。
IF 5.9 Q1 Computer Science Pub Date : 2022-02-11 eCollection Date: 2022-06-01 DOI: 10.1007/s41666-022-00114-1
Christopher C Yang

The principle behind artificial intelligence is mimicking human intelligence in the way that it can perform tasks, recognize patterns, or predict outcomes through learning from the acquired data of various sources. Artificial intelligence and machine learning algorithms have been widely used in autonomous driving, recommender systems in electronic commerce and social media, fintech, natural language understanding, and question answering systems. Artificial intelligence is also gradually changing the landscape of healthcare research (Yu et al. in Biomed Eng 2:719-731, 25). The rule-based approach that relied on the curation of medical knowledge and the construction of robust decision rules had drawn significant attention in diagnosing diseases and clinical decision support since half a century ago. In recent years, machine learning algorithms such as deep learning that can account for complex interactions between features is shown to be promising in predictive modeling in healthcare (Deo in Circulation 132:1920-1930, 26). Although many of these artificial intelligence and machine learning algorithms can achieve remarkably high performance, it is often difficult to be completely adopted in practical clinical environments due to the lack of explainability in some of these algorithms. Explainable artificial intelligence (XAI) is emerging to assist in the communication of internal decisions, behavior, and actions to health care professionals. Through explaining the prediction outcomes, XAI gains the trust of the clinicians as they may learn how to apply the predictive modeling in practical situations instead of blindly following the predictions. There are still many scenarios to explore how to make XAI effective in clinical settings due to the complexity of medical knowledge.

人工智能背后的原理是模仿人类智能,通过从各种来源获得的数据中学习来执行任务、识别模式或预测结果。人工智能和机器学习算法已广泛应用于自动驾驶、电子商务和社交媒体的推荐系统、金融科技、自然语言理解和问答系统。人工智能也在逐渐改变医疗保健研究的格局(Yu et al. in Biomed Eng 2:719-731, 25)。半个世纪以来,基于规则的方法依赖于医学知识的管理和健全决策规则的构建,在疾病诊断和临床决策支持方面引起了极大的关注。近年来,机器学习算法,如深度学习,可以解释特征之间复杂的相互作用,在医疗保健的预测建模中被证明是有前途的(Deo In Circulation 132:1920-1930, 26)。尽管这些人工智能和机器学习算法中有许多可以实现非常高的性能,但由于其中一些算法缺乏可解释性,通常难以在实际临床环境中完全采用。可解释的人工智能(XAI)正在兴起,以协助与医疗保健专业人员进行内部决策、行为和行动的沟通。通过对预测结果的解释,XAI获得了临床医生的信任,因为他们可以学习如何将预测模型应用于实际情况,而不是盲目地遵循预测。由于医学知识的复杂性,如何使XAI在临床环境中发挥作用仍有许多场景需要探索。
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引用次数: 33
A Case Study of Bluetooth Technology as a Supplemental Tool in Contact Tracing. 蓝牙技术作为接触追踪补充工具的案例研究。
IF 5.9 Q1 Computer Science Pub Date : 2022-01-19 eCollection Date: 2022-06-01 DOI: 10.1007/s41666-021-00112-9
Ryan Admiraal, Jules Millen, Ankit Patel, Tim Chambers

We present results from a 7-day trial of a Bluetooth-enabled card by the New Zealand Ministry of Health to investigate its usefulness in contact tracing. A comparison of the card with traditional contact tracing, which relies on self-reports of contacts to case investigators, demonstrated significantly higher levels of internal consistency in detected contact events by Bluetooth-enabled cards with 88% of contact events being detected by both cards involved in an interaction as compared to 64% for self-reports of contacts to case investigators. We found no clear evidence of memory recall worsening in reporting contact events that were further removed in time from the date of a case investigation. Roughly 66% of contact events between trial participants that were indicated by cards went unreported to case investigators, simultaneously highlighting the shortcomings of traditional contact tracing and the value of Bluetooth technology in detecting contact events that may otherwise go unreported. At the same time, cards detected only 65% of self-reported contact events, in part due to increasing non-compliance as the study progressed. This would suggest that Bluetooth technology can only be considered as a supplemental tool in contact tracing and not a viable replacement to traditional contact tracing unless measures are introduced to ensure greater compliance.

我们介绍了新西兰卫生部对蓝牙卡进行的为期7天的试验结果,以调查其在接触者追踪中的有用性。传统的接触者追踪依赖于向案件调查员自我报告的接触者,将这种卡与传统的接触者追踪进行比较,结果表明,蓝牙卡在检测到的接触事件中具有明显更高的内部一致性,参与互动的两张卡都检测到88%的接触事件,而向案件调查员自我报告的接触者为64%。我们没有发现明确的证据表明,在报告接触事件时,从病例调查之日起进一步删除的记忆回忆恶化。通过卡片显示的试验参与者之间的接触事件中,大约66%没有报告给案件调查员,同时突出了传统接触追踪的缺点,以及蓝牙技术在检测可能未报告的接触事件方面的价值。与此同时,卡片只检测到65%的自我报告的接触事件,部分原因是随着研究的进展,不遵守规定的情况越来越多。这表明蓝牙技术只能被视为接触追踪的补充工具,而不是传统接触追踪的可行替代品,除非采取措施确保更大的合规性。
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引用次数: 2
Extended SEIR Model for Health Policies Assessment Against the COVID-19 Pandemic: the Case of Argentina. COVID-19大流行卫生政策评估的扩展SEIR模型:以阿根廷为例
IF 5.9 Q1 Computer Science Pub Date : 2022-01-01 Epub Date: 2021-12-07 DOI: 10.1007/s41666-021-00110-x
Fernando A Inthamoussou, Fernando Valenciaga, Sebastián Núñez, Fabricio Garelli

This work presents an extended and age-band compartmentalised SEIR model that allows describing the spread evolution of SARS-CoV-2 and evaluating the effect of different detection rates, vaccination strategies or immunity periods. The model splits up the population into fifteen age groups of 5 years each, linked through a statistical interaction matrix that includes seventeen health states within each age group. An age-dependent transmission rate takes into account infectious between the groups as well the effect of interventions such as quarantines and mobility restrictions. Further, the proposal includes a nonlinear switched controller for model tuning purposes guarantying a simple and fast adjusting process. To illustrate the model potentials, the particular case of COVID-19 evolution in Argentina is analysed by simulation of three scenarios: (i) different detection levels combined with mobility restrictions, (ii) vaccination campaigns with re-opening of activities and (iii) vaccination campaigns with possible reinfections. The results exhibit how the model can aid the authorities in the decision making process.

这项工作提出了一个扩展的、年龄层划分的SEIR模型,该模型可以描述SARS-CoV-2的传播演变,并评估不同检出率、疫苗接种策略或免疫期的影响。该模型将人口分为15个年龄组,每个年龄组5岁,通过统计交互矩阵联系起来,其中包括每个年龄组内的17个健康状态。年龄相关的传播率考虑到群体之间的传染性以及隔离和限制流动等干预措施的影响。此外,该方案还包括一个用于模型调谐的非线性切换控制器,以保证简单快速的调节过程。为了说明模型的潜力,通过模拟三种情景,分析了阿根廷COVID-19演变的具体案例:(i)结合流动限制的不同检测水平,(ii)重新开放活动的疫苗接种运动,以及(iii)可能再次感染的疫苗接种运动。结果显示了该模型如何在决策过程中帮助当局。
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引用次数: 3
Experimental Technologies in the Diagnosis and Treatment of COVID-19 in Patients with Comorbidities. 新冠肺炎合并症患者诊治实验技术研究
IF 5.9 Q1 Computer Science Pub Date : 2022-01-01 Epub Date: 2021-09-15 DOI: 10.1007/s41666-021-00106-7
Md Shahnoor Amin, Marcin Wozniak, Lidija Barbaric, Shanel Pickard, Rahul S Yerrabelli, Anton Christensen, Olivia C Coiado

The COVID-19 pandemic has impacted the whole world and raised concerns about its effects on different human organ systems. Early detection of COVID-19 may significantly increase the rate of survival; thus, it is critical that the disease is detected early. Emerging technologies have been used to prevent, diagnose, and manage COVID-19 among the populace in the USA and globally. Numerous studies have revealed the growing implementation of novel engineered systems during the intervention at various points of the disease's pathogenesis, especially as it relates to comorbidities and complications related to cardiovascular and respiratory organ systems. In this review, we provide a succinct, but extensive, review of the pathogenesis of COVID-19, particularly as it relates to angiotensin-converting enzyme 2 (ACE2) as a viral entry point. This is followed by a comprehensive analysis of cardiovascular and respiratory comorbidities of COVID-19 and novel technologies that are used to diagnose and manage hospitalized patients. Continuous cardiorespiratory monitoring systems, novel machine learning algorithms for rapidly triaging patients, various imaging modalities, wearable immunosensors, hotspot tracking systems, and other emerging technologies are reviewed. COVID-19 effects on the immune system, associated inflammatory biomarkers, and innovative therapies are also assessed. Finally, with emphasis on the impact of wearable and non-wearable systems, this review highlights future technologies that could help diagnose, monitor, and mitigate disease progression. Technologies that account for an individual's health conditions, comorbidities, and even socioeconomic factors can drastically reduce the high mortality seen among many COVID-19 patients, primarily via disease prevention, early detection, and pertinent management.

COVID-19大流行影响全球,并引起人们对其对人体不同器官系统影响的担忧。早期发现COVID-19可显著提高生存率;因此,及早发现这种疾病至关重要。新兴技术已被用于在美国和全球民众中预防、诊断和管理COVID-19。大量研究表明,在疾病发病机制的各个阶段,特别是与心血管和呼吸器官系统相关的合并症和并发症的干预中,越来越多地实施了新型工程系统。在这篇综述中,我们对COVID-19的发病机制进行了简要而广泛的回顾,特别是与作为病毒入口点的血管紧张素转换酶2 (ACE2)有关。随后全面分析了COVID-19的心血管和呼吸合并症以及用于诊断和管理住院患者的新技术。本文综述了连续心肺监测系统、用于快速分诊患者的新型机器学习算法、各种成像模式、可穿戴免疫传感器、热点跟踪系统和其他新兴技术。还评估了COVID-19对免疫系统、相关炎症生物标志物和创新疗法的影响。最后,本文重点介绍了可穿戴和非可穿戴系统的影响,重点介绍了有助于诊断、监测和缓解疾病进展的未来技术。考虑到个人健康状况、合并症甚至社会经济因素的技术,可以主要通过疾病预防、早期发现和相关管理,大幅降低许多COVID-19患者的高死亡率。
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引用次数: 1
Analyzing the Impact of Demographic Variables on Spreading and Forecasting COVID-19. 人口统计变量对COVID-19传播和预测的影响分析
IF 5.9 Q1 Computer Science Pub Date : 2022-01-01 Epub Date: 2021-09-16 DOI: 10.1007/s41666-021-00105-8
Omar Sharif, Md Rafiqul Islam, Md Zobaer Hasan, Muhammad Ashad Kabir, Md Emran Hasan, Salman A AlQahtani, Guandong Xu

The aim of this study is to analyse the coronavirus disease 2019 (COVID-19) outbreak in Bangladesh. This study investigates the impact of demographic variables on the spread of COVID-19 as well as tries to forecast the COVID-19 infected numbers. First of all, this study uses Fisher's Exact test to investigate the association between the infected groups of COVID-19 and demographical variables. Second, it exploits the ANOVA test to examine significant difference in the mean infected number of COVID-19 cases across the population density, literacy rate, and regions/divisions in Bangladesh. Third, this research predicts the number of infected cases in the epidemic peak region of Bangladesh for the year 2021. As a result, from the Fisher's Exact test, we find a very strong significant association between the population density groups and infected groups of COVID-19. And, from the ANOVA test, we observe a significant difference in the mean infected number of COVID-19 cases across the five different population density groups. Besides, the prediction model shows that the cumulative number of infected cases would be raised to around 500,000 in the most densely region of Bangladesh, Dhaka division.

本研究的目的是分析孟加拉国2019年冠状病毒病(COVID-19)的爆发。本研究调查了人口统计学变量对COVID-19传播的影响,并试图预测COVID-19感染人数。首先,本研究使用Fisher's Exact检验来研究COVID-19感染群体与人口统计学变量之间的关联。其次,它利用方差分析检验了孟加拉国不同人口密度、识字率和地区/地区的COVID-19病例平均感染人数的显著差异。第三,本研究预测了2021年孟加拉国疫情高峰地区的感染病例数。因此,从费雪精确检验中,我们发现人口密度组与COVID-19感染组之间存在非常强的显著关联。而且,从方差分析检验中,我们观察到五个不同人口密度组的COVID-19病例平均感染人数存在显著差异。此外,预测模型显示,在孟加拉国人口最密集的地区达卡区,累计感染病例将增加到50万左右。
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引用次数: 3
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Journal of Healthcare Informatics Research
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