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Utility of type and screen policy for pretransfusion compatibility testing at an urban level Ι apex trauma center 在城市一级输血前相容性测试的类型和筛选政策的效用Ι顶点创伤中心
Q3 Nursing Pub Date : 2021-09-28 DOI: 10.34172/jept.2021.26
Rahul Chaurasia, N. Akhtar, S. Arulselvi, V. Arya, Sulekha Karjee
Objective: Type and crossmatch (TC) policy is the most common approach for pre-transfusion compatibility testing prior to issue of blood for transfusion. As it involves reserving of the blood units (usually up to 72 hours) prior to issue or un-reserving, it can lead to excessive blood cross matching, inventory management problems, undue workload, blood outdating and reagent wastage. Type and screen (TS) policy is an alternative approach without the need to cross match and reserve blood units prior to issue. The aim of the current study was to retrospectively assess the impact of the implementation of TS policy for pre-transfusion compatibility testing on blood transfusion services at an urban level Ι trauma center. Methods: The study was done in two phases in the Department of Transfusion Medicine at Jai Prakash Narayan Apex Trauma Center AIIMS, New Delhi, India. Transfusion data was collected and compared during two phases: initial phase (Oct 2016-Mar 2017) of TC policy and second phase (Apr 2017-Sept 2017) of TS policy. Results: TS policy resulted in the reduction of C:T ratio from 5.3 to 1.9. Transfusion probability increased to 29.5% during TS policy from 23.6% during TC policy. Issuable stock index (ISI) also showed reduction from 12.5 to 11.4 after TS policy. Wastage as percentage of issue (WAPI) was reduced from 2.3% (TC) to 1.3% (TS). TS policy also led to reduction in expenses incurred on pre-transfusion compatibility testing by 35%. No hemolytic transfusion reaction was reported during the study. Conclusion: TS policy was found to be a safe and an efficient alternative approach to TC policy for pre-transfusion compatibility at our center. We recommend the implementation of TS policy, but each center should first assess its feasibility based on patient population, blood bank resources and staff knowledge.
目的:类型和交叉配型(TC)政策是在输血前进行输血前兼容性测试的最常见方法。由于它涉及在发放或取消储备前储备血液单位(通常长达72小时),可能会导致过度的血液交叉匹配、库存管理问题、过度的工作量、血液过期和试剂浪费。类型和筛选(TS)策略是一种替代方法,无需在发布前交叉匹配和储备血液单位。本研究的目的是回顾性评估TS政策对城市创伤中心输血服务的影响。方法:该研究在印度新德里Jai Prakash Narayan Apex创伤中心的输血医学科分两个阶段进行。在两个阶段收集并比较了输血数据:TC政策的初始阶段(2016年10月至2017年3月)和TS政策的第二阶段(2017年4月至2017月至9月)。结果:TS政策使C:T比率从5.3降低到1.9。TS政策期间的输血概率从TC政策期间的23.6%增加到29.5%。TS政策实施后,可发行股票指数(ISI)也从12.5降至11.4。浪费占问题的百分比(WAPI)从2.3%(TC)降低到1.3%(TS)。TS政策还使输血前兼容性测试的费用减少了35%。研究期间未报告溶血性输血反应。结论:在我们中心,TS策略是一种安全有效的TC策略的替代方法。我们建议实施TS政策,但每个中心应首先根据患者群体、血库资源和员工知识评估其可行性。
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引用次数: 0
Base of skull fracture leading to pneumomediastinum and pneumo-retroperitoneum: a case report with review of literature 颅底骨折致纵隔气和腹膜后气1例并文献复习
Q3 Nursing Pub Date : 2021-09-27 DOI: 10.34172/jept.2021.25
G. Sharma, Sanya Vermani, A. Syed
Objective: The presence of air within the mediastinal compartment and retro-peritoneal compartment, in the setting of trauma, can be because of visceral and skeletal injuries. However, in absence of a local site injury, an approach based on anatomical communication between various body compartments should be utilized and all potential sites of injuries must be reviewed. Case Presentation: We present a case of a 40-year-old male patient with a history of trauma (fall from height), presenting to the emergency department with loss of consciousness and ear bleed. Chest radiographs showed pneumomediastinum. On cross-sectional imaging, pneumomediastinum and pneumoretroperitoneum were seen, however no esophageal, tracheal and skeletal injuries could be identified. On careful evaluation, fractures involving the base of skull were identified as a source of ectopic air. Conclusion: This case represents a situation where the fascial connections between various compartments of the body were utilized to find the site of injury and hence the source of ectopic air. Base of skull fractures are important to be identified since these require surgical attention at an early stage.
目的:在创伤的情况下,纵隔隔室和腹膜后隔室内存在空气,可能是因为内脏和骨骼损伤。然而,在没有局部损伤的情况下,应采用基于不同身体隔间之间解剖交流的方法,并且必须对所有潜在的损伤部位进行审查。病例介绍:我们介绍了一例40岁的男性患者,他有创伤史(从高处坠落),在急诊科出现意识丧失和耳出血。胸部X线片显示纵隔气肿。横断面影像显示纵隔气肿和腹膜后气肿,但未发现食道、气管和骨骼损伤。经过仔细评估,涉及颅底的骨折被确定为异位空气的来源。结论:该病例代表了一种情况,即利用身体各隔间之间的筋膜连接来寻找损伤部位,从而找到异位空气的来源。颅底骨折很重要,因为这些骨折需要在早期进行手术治疗。
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引用次数: 0
Predictive value of HEART score in the outcome of acute coronary syndrome and disposition HEART评分对急性冠状动脉综合征结局及预后的预测价值
Q3 Nursing Pub Date : 2021-07-23 DOI: 10.34172/JEPT.2021.17
A. Abbasian, Maryam Beladi, Elnaz Vahidi, Amirhosein Jahanshir, Javad Seyedhosseini
Objective: Disposition in acute coronary syndrome (ACS) is pivotal in an emergency department (ED). HEART score is a recent scoring system for finding primary endpoints in undetermined ACS. This study aimed at evaluating the predictive value of HEART score in ACS outcome and disposition. Methods: In this prospective study, all patients with chest pain presentation compatible with our inclusion criteria referring to ED were enrolled during one year. Demographic data, triage level, hospital length of stay, admission ward, coronary angiography result, HEART score, thrombolysis in myocardial infarction (TIMI) score, 1-month primary ACS endpoints and major adverse cardiac events (MACE) were evaluated. Results: In our studied population (200 cases), 49 patients (24.5%) had at least one score for MACE. Comparing the prognostic values of TIMI vs HEART score in MACE revealed that the HEART had a larger AUC. The best cut-off point of HEART score in MACE prediction was calculated to be ≥5. There was a statistically significant relation between HEART score and hospital length of stay. The higher the HEART score, the more probability of patients being admitted to either hospital cardiac ward or coronary care unit (CCU). There was a significant relationship between the triage level and HEART score. Patients with higher HEART score had more acuity (lower triage level 1 or 2). Conclusion: HEART predicted MACE better than TIMI in low risk ACS. Patients with higher HEART score were more admitted to the hospital with longer hospital stay and patients with lower HEART score had higher triage level with less acuity.
目的:急性冠脉综合征(ACS)的处置是急诊科(ED)的关键。HEART评分是一种最新的评分系统,用于寻找未确定ACS的主要终点。本研究旨在评估心脏评分对ACS预后和处置的预测价值。方法:在这项前瞻性研究中,所有胸痛表现符合ED纳入标准的患者在一年内入组。评估人口学资料、分诊级别、住院时间、住院病房、冠状动脉造影结果、HEART评分、心肌梗死溶栓(TIMI)评分、1个月主要ACS终点和主要心脏不良事件(MACE)。结果:在我们的研究人群(200例)中,49例(24.5%)患者至少有一次MACE评分。比较MACE中TIMI和HEART评分的预后价值,发现HEART的AUC更大。计算得出心脏评分在MACE预测中的最佳分界点≥5。心脏评分与住院时间有统计学意义。HEART评分越高,患者入住医院心脏病房或冠状动脉监护病房(CCU)的可能性越大。分诊水平与心脏评分有显著相关。HEART评分越高的患者的敏锐度越高(分诊等级1级或2级较低)。结论:HEART比TIMI更能预测低危ACS患者的MACE。HEART评分较高的患者住院时间较长,而HEART评分较低的患者分诊水平较高,视力较差。
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引用次数: 0
Pattern of injuries in blunt trauma abdomen: A retrospective evaluation of imaging findings at a high-volume tertiary care trauma centre 钝性腹部创伤的损伤模式:在一个大容量三级护理创伤中心对影像学结果的回顾性评估
Q3 Nursing Pub Date : 2021-06-17 DOI: 10.34172/jept.2021.18
V. Bhatia, Suzanne Koshi, Varun Bansal, U. Debi, Lokesh Singh, M. Sandhu
Objective: Contrast-enhanced computed tomography (CECT) is the investigation of choice in trauma patients. The purpose of this study was to retrospectively evaluate the pattern, severity and association of abdominal injuries based on imaging at a high-volume tertiary trauma care centre. Methods: Retrospective evaluation of the CT records of patients over a period of 5 years was done at our institute. A total of 1519 patients who had undergone contrast-enhanced abdominal CT at a 64-slice Multidetector CT for abdominal trauma were included in this study. Inclusion criteria were: 1) History of blunt abdominal trauma, 2) Patients who had undergone a biphasic CECT abdomen scan. Exclusion criteria were: 1) Patients with penetrating injury, 2) Patients with incomplete data set/records. Results: Liver was the most common injured organ in both adult (38.8%) and paediatric population (40.9%). Significant higher incidence of mesenteric injury, bladder injury, spinal and rib fractures were seen in adult patients. Significant association of anorectal injuries (P=0.003) and bladder/urethral injuries with pelvic fractures was also seen (P<0.001). Conclusion: Our study provided important insights about the pattern, severity and association between the various abdominal injuries based on imaging findings in a large patient population. Larger studies with incorporation of clinical outcome in such patients can help in formulating appropriate management strategies.
目的:探讨对比增强计算机断层扫描(CECT)在创伤患者中的应用价值。本研究的目的是回顾性评估基于大容量三级创伤护理中心的腹部损伤的成像模式、严重程度和相关性。方法:回顾性分析我院近5年患者的CT记录。本研究共纳入1519例经64层多层螺旋CT增强腹部CT检查腹部创伤的患者。纳入标准为:1)钝性腹部外伤史;2)接受过双期CECT腹部扫描的患者。排除标准为:1)穿透性损伤患者;2)资料集/记录不完整的患者。结果:肝脏是成人(38.8%)和儿童(40.9%)中最常见的损伤器官。成人患者肠系膜损伤、膀胱损伤、脊柱和肋骨骨折的发生率明显高于成人。肛门直肠损伤(P=0.003)和膀胱/尿道损伤与骨盆骨折也有显著相关性(P<0.001)。结论:我们的研究基于大量患者的影像学发现,对各种腹部损伤的模式、严重程度和相关性提供了重要的见解。纳入此类患者临床结果的大型研究有助于制定适当的管理策略。
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引用次数: 0
Pharmacoligical characterization of the iranian Cerastes cerastes gasperettii (Reptilia: Ophidia: Viperidae) venom 伊朗蜡蚧(爬行纲:蛇亚目:蝰蛇科)毒液的药理学特征
Q3 Nursing Pub Date : 2021-06-17 DOI: 10.34172/JEPT.2021.22
S. Zaeri, Z. Aghaei, N. Mashayekhi, A. Salemi, R. Seyedian
Objective: Snake envenomation is common in tropical and subtropical countries of the Middle East areas including Iran. Cerastes cerastes gasperettii is a dangerous snake living in southwestern provinces of Iran. It causes massive edema at the bite site and coagulopathy leading to death if untreated. Methods: The purpose of this preliminary animal study was to evaluate the toxicity and proteomic of this venom for the first time in Iran. Moreover, the hemodynamic changes with intravenous injection of the venom were assessed and inotropic in addition to arrhythmogenic properties of this venom were investigated. Results: The estimated amount of the LD50 with intraperitoneal injection was slightly less than the similar experiment in Saudi Arabia (1.32 mg/kg versus 978 µg/kg body weight). There were 8 distinct protein bands between 12 and 66 kDa in SDS-PAGE analysis that were different with Moroccan experiment due to inter and intra species variation. Inotropic potencies were not significant since the lethal dose with intravenous injection was much lower than the Arabian experiment in guinea pigs (2.4 mg/kg versus 0.8 mg/kg). Conclusion: According to the low hemodynamic changes induced with the venom, it seems that coagulopathy and edema are the most dangerous effects of this rare snake in Iran.
目的:蛇中毒在包括伊朗在内的中东地区的热带和亚热带国家很常见。cerecastgasperettii是一种生活在伊朗西南部省份的危险蛇。如果不治疗,它会在咬伤部位引起大面积水肿和凝血功能障碍,导致死亡。方法:首次在伊朗对该毒液的毒性和蛋白质组学进行初步的动物研究。此外,我们还评估了静脉注射该毒液后血液动力学的变化,并研究了该毒液的肌力和致心律失常特性。结果:腹腔注射LD50的估计量略低于沙特阿拉伯的类似实验(1.32 mg/kg vs 978µg/kg体重)。由于种内和种间的差异,SDS-PAGE分析结果显示在12 ~ 66 kDa之间有8条不同的蛋白带,与摩洛哥实验结果不同。由于静脉注射的致死剂量远低于阿拉伯实验中的豚鼠(2.4 mg/kg对0.8 mg/kg),因此肌力的效力并不显著。结论:根据该毒液引起的低血流动力学变化,凝血功能障碍和水肿似乎是该伊朗稀有蛇最危险的影响。
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引用次数: 1
The challenge of medication errors in the emergency department setting 急诊科设置中药物错误的挑战
Q3 Nursing Pub Date : 2021-06-17 DOI: 10.34172/JEPT.2021.19
Mojtaba Miladinia, Elham Mousavi Nouri
Medication errors (MEs) are considered the most common medical errors and as one of the major challenges threatening the health system, which can be also reduced. MEs threaten patients' safety and may increase the length of hospital stay, lead to unexpected complications, mortality and side costs. In 2017, the World Health Organization launched Medication without Harm to reduce severe avoidable medication-related damage by 50%, globally in the next 5 years. Emergency Departments (EDs) are stressful care environments which making EDs more prone to MEs. Therefore, EDs need to be seriously considered to reduce MEs and increase patients' safety. In this regard, it is of great significance to know about the most common stage of error in pharmacotherapy, the most common type of medication error and the most common causes of MEs in the emergency department practice setting. in conclusion, the most common types of MEs in EDs include drug omission error, wrong dose and strong infusion rate. In addition, the administration and prescribing are the most common stages of MEs in EDs. Also, the most common causes of MEs in EDs in Iran include nursing shortage (fatigue) and poor medication knowledge .
用药错误被认为是最常见的医疗错误,也是威胁卫生系统的主要挑战之一,也可以减少。脑脊髓炎威胁患者的安全,可能会延长住院时间,导致意外并发症、死亡率和副作用。2017年,世界卫生组织推出了“无伤害用药”,以在未来5年内将全球可避免的严重药物相关损害减少50%。急诊科是一种压力很大的护理环境,使急诊科更容易发生脑脊髓炎。因此,需要认真考虑ED,以减少ME并提高患者的安全性。在这方面,在急诊科实践环境中了解药物治疗中最常见的错误阶段、最常见的药物错误类型和最常见的ME原因具有重要意义。总之,ED中最常见的ME类型包括药物遗漏错误、错误剂量和强输注率。此外,给药和开药是ED中最常见的ME阶段。此外,伊朗ED中ME最常见的原因包括护理短缺(疲劳)和药物知识不足。
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引用次数: 0
Interleukin-6 blockade and cytokine release syndrome in coronavirus disease of 2019: Is that a lot? Thoughts from the emergency department 2019冠状病毒病中白细胞介素-6阻断和细胞因子释放综合征:很多吗?来自急诊科的想法
Q3 Nursing Pub Date : 2021-06-05 DOI: 10.34172/jept.2021.21
S. Sheikh
Interleukin-6 is pro-inflammatory cytokine which plays a role in cytokine storm and brought into notice with corona virus disease of 2019. Lymphopenia and dysregulated immune response were seen in the critically ill patients of corona virus disease of 2019. IL-6 inhibitors were proposed as a treatment option in this pandemic with a concept that it will reduce inflammation, infection and organ failure. Tocilizumab, a monoclonal antibody against soluble and membrane IL‐6 receptors was considered as forefront treatment option as it was used previously in rheumatologic disorder as a licensed agent. Tocilizumab is an immunosuppressive agent and serious or fatal infections could occur. Presence of superimposed bacterial infections in critically ill patients with corona virus disease of 2019 should be aggressively treated. However clinical experiences showed higher rates of superimposed bacterial infections which renders for extreme caution while prescribing such therapies. Perspective is needed when using the rheumatologic literature of IL-6 into corona virus disease of 2019 and their range observed in these conditions.
白细胞介素-6是一种促炎细胞因子,在细胞因子风暴中发挥作用,并在2019年的冠状病毒病中引起注意。在2019年冠状病毒病的危重患者中发现了淋巴细胞减少和免疫反应失调。IL-6抑制剂被提议作为这场疫情的一种治疗选择,其理念是可以减少炎症、感染和器官衰竭。托奇利珠单抗是一种针对可溶性和膜IL-6受体的单克隆抗体,被认为是最前沿的治疗选择,因为它以前曾作为许可药物用于风湿病。托奇利珠单抗是一种免疫抑制剂,可能会发生严重或致命的感染。应积极治疗2019年冠状病毒病危重患者中存在的叠加细菌感染。然而,临床经验显示,叠加细菌感染率更高,这使得在开具此类疗法处方时格外谨慎。当将IL-6的风湿病文献用于2019年的冠状病毒病及其在这些条件下观察到的范围时,需要有足够的视角。
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引用次数: 0
An overview of the prevalence and pattern of maxillofacial trauma in the south of Iran 在伊朗南部的流行和颌面创伤的模式的概述
Q3 Nursing Pub Date : 2021-06-01 DOI: 10.34172/JEPT.2021.13
Mahnaz Yadollahi, Sarina Sahmeddini
Objective: The purpose of the current study is to determine the prevalence and pattern of maxillofacial trauma. Methods: This is a cross sectional study of maxillofacial trauma cases treated in the referral trauma center of south of Iran. Data of 264 patients were extracted from patients’ records and analyzed. Data included patient’s demographics, injury mechanism, types of maxillofacial injuries, Injury Severity Score (ISS), associated injuries, length of hospital stay and outcome. Binary logistic regression by backward method was applied to determine the effects of independent variables on mortality odds ratio. Results: 85.23% of patients were males and of all patients 87.5% survived. The mean of age was 34.95 ± 16.51. The commonest cause of maxillofacial injury was road traffic accidents (86.31%). The median of ISS was 20.39± 10.24 and patients aged 30-39 years had the highest ISS. Overall, the most common maxillofacial injuries were orbital (59.47%, n=157) followed by maxillary (48.11%, n=127); common associated injuries were related to head (81.44%, n=215) followed by thorax (58.33%, n=154). Age and gender (being male) increased the odds ratio of mortality. An increase in ISS decreased the odds ratio of mortality, but it was not significant. Conclusion: Most of maxillofacial trauma patients suffered from orbital injuries and there were a huge percentage of associated injuries. Gender (male), age and length of hospital stay were the significant variables of mortality in maxillofacial patients. The findings of the current study sheds light on further investigation to treat these patients and enforce road traffic legislation and public education to prevent these traumas.
目的:了解颌面部外伤的发生率和类型。方法:这是一个在伊朗南部转诊创伤中心治疗的颌面创伤病例的横断面研究。从病历中提取264例患者资料进行分析。数据包括患者的人口统计学、损伤机制、颌面部损伤类型、损伤严重程度评分(ISS)、相关损伤、住院时间和结果。采用反向二元logistic回归法确定自变量对死亡率比值比的影响。结果:85.23%的患者为男性,生存率为87.5%。平均年龄34.95±16.51岁。颌面部损伤最常见的原因是道路交通事故(86.31%)。ISS的中位值为20.39±10.24,其中30-39岁患者ISS最高。总的来说,最常见的颌面部损伤是眶部(59.47%,n=157),其次是上颌(48.11%,n=127);常见的伴发损伤为头部(81.44%,n=215),其次为胸部(58.33%,n=154)。年龄和性别(男性)增加了死亡率的优势比。ISS的增加降低了死亡率的优势比,但并不显著。结论:颌面部外伤患者以眶部损伤为主,伴发损伤占很大比例。性别(男性)、年龄和住院时间是颌面部患者死亡率的显著变量。目前的研究结果为进一步的调查提供了线索,以治疗这些病人,并加强道路交通立法和公共教育,以防止这些创伤。
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引用次数: 2
Posterior reversible encephalopathy syndrome due to COVID-19 COVID-19所致后部可逆性脑病综合征
Q3 Nursing Pub Date : 2021-06-01 DOI: 10.34172/jept.2021.11
M. Al-Kaisy
Objective: During the late 2019, a group of patients had unexplained chest infections in Wuhan which turned out to be the new pandemic coronavirus disease 2019 (COVID-19). New neurological symptoms have been reported in COVID-19 patients. Posterior reversible encephalopathy syndrome (PRES) is a new neurological finding and is associated or caused by COVID-19. Case Presentation: A 32-year-old lady, with no medical background had COVID-19 infection and needed mechanical ventilation. After surviving the intensive care, she started to have multiple seizures that required general anesthesia to be aborted. The patient turned out to have PRES. Conclusion: PRES is a neurological syndrome causing seizures, headaches, and blurred vision. It is usually associated with high blood pressure, renal failure, and other risk factors. The patient in this case had nearly normal blood pressure, but still had a diagnosis of PRES. The new reported neurological symptoms associated with COVID-19 infection need further research and attention from the academic society to predict and prevent the morbidity and mortality of COVID-19 patients.
目的:2019年末,武汉一组患者出现不明原因的胸部感染,这是2019新型冠状病毒病(新冠肺炎)。据报道,新冠肺炎患者出现了新的神经系统症状。后可逆性脑病综合征(PRES)是一种新的神经学发现,与新冠肺炎相关或由其引起。病例介绍:一名32岁的女士,无医学背景,感染了新冠肺炎,需要机械通气。在重症监护中幸存下来后,她开始出现多次癫痫发作,需要全身麻醉才能流产。结论:PRES是一种引起癫痫发作、头痛和视力模糊的神经系统综合征。它通常与高血压、肾衰竭和其他危险因素有关。该病例中的患者血压几乎正常,但仍被诊断为PRES。新报告的与新冠肺炎感染相关的神经系统症状需要学术社会的进一步研究和关注,以预测和预防新冠肺炎患者的发病率和死亡率。
{"title":"Posterior reversible encephalopathy syndrome due to COVID-19","authors":"M. Al-Kaisy","doi":"10.34172/jept.2021.11","DOIUrl":"https://doi.org/10.34172/jept.2021.11","url":null,"abstract":"Objective: During the late 2019, a group of patients had unexplained chest infections in Wuhan which turned out to be the new pandemic coronavirus disease 2019 (COVID-19). New neurological symptoms have been reported in COVID-19 patients. Posterior reversible encephalopathy syndrome (PRES) is a new neurological finding and is associated or caused by COVID-19. Case Presentation: A 32-year-old lady, with no medical background had COVID-19 infection and needed mechanical ventilation. After surviving the intensive care, she started to have multiple seizures that required general anesthesia to be aborted. The patient turned out to have PRES. Conclusion: PRES is a neurological syndrome causing seizures, headaches, and blurred vision. It is usually associated with high blood pressure, renal failure, and other risk factors. The patient in this case had nearly normal blood pressure, but still had a diagnosis of PRES. The new reported neurological symptoms associated with COVID-19 infection need further research and attention from the academic society to predict and prevent the morbidity and mortality of COVID-19 patients.","PeriodicalId":36499,"journal":{"name":"Journal of Emergency Practice and Trauma","volume":"4 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41263590","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Emergency laparotomy at district hospitals in a developing nation: a review of indications and outcomes of treatment 发展中国家地区医院急诊剖腹手术的适应症和治疗结果综述
Q3 Nursing Pub Date : 2021-06-01 DOI: 10.34172/JEPT.2021.06
A. Ogbuanya, N. Ugwu
Objective: Recently, emergency and essential surgical and anesthesia care at district hospitals is increasingly gaining recognition as a critical, though neglected element of health care system in Africa and other developing nations. Emergency laparotomy is a versatile procedure that can cure a great deal of acute abdominal conditions. The aim of this study was to document the indications and outcomes of laparotomy for emergency abdominal surgical conditions in our district hospitals. Methods: This retrospective study was undertaken in district hospitals from January 2009 to December 2018. Associations between different variables were measured and compared using statistical tests of significance. Results: Of the 879 patients evaluated, appendicitis (n=361, 41.1%) was the most frequent indication for emergency laparotomy followed by complicated external hernias (n=120, 13.7%). Other indications were adhesive intestinal obstruction (n=111, 12.6%), typhoid perforation (n=98, 11.1%), perforated peptic ulcer (n=89, 10.1%), trauma (n=58, 6.6%), colorectal cancer (CRC) (n=18, 2.0%) and others (n=24, 2.8%). The vast majority of patients (n=726, 82.6%) were presented after 24 hours of the onset of disease. Approximately, one-third of patients (n=278, 31.6%) had comorbidities, 867 (98.6%) had high ASA scores (III and IV) and 105 (11.9%) received intestinal resection with or without stoma. The main independent predictors of mortality were late presentation (P=0.003), generalized peritonitis (P=0.001), bowel resection (P=0.000) and high ASA (III and IV) scores (P=.000). Overall, the mortality rate was 10.6%. The commonest complication was wound infection (39.7%), followed by intra-abdominal collection (10.0%). Conclusion: The most common indication for emergency laparotomy was appendicitis followed by complicated hernias. The major independent predictors of mortality included bowel resection, high ASA score, late presentation and generalized peritonitis.
目的:最近,在非洲和其他发展中国家,地区医院的急诊和基本外科和麻醉护理越来越被视为医疗保健系统中一个关键但被忽视的组成部分。急诊剖腹手术是一种多功能的手术,可以治愈许多急性腹部疾病。本研究的目的是记录我们地区医院在紧急腹部手术条件下剖腹手术的适应症和结果。方法:本回顾性研究于2009年1月至2018年12月在地区医院进行。不同变量之间的相关性通过显著性统计检验进行测量和比较。结果:在879例患者中,阑尾炎(n=361,41.1%)是最常见的急诊剖腹手术指征,其次是复杂的外部疝(n=120,13.7%)。其他指征为粘连性肠梗阻(n=111,12.6%)、伤寒穿孔(n=98,11.1%)、消化性溃疡穿孔(n=89,10.1%)、创伤(n=58,6.6%),癌症(n=18,2.0%)和其他(n=24,2.8%)。绝大多数患者(n=726,82.6%)在发病24小时后出现。大约三分之一的患者(n=278,31.6%)有合并症,867(98.6%)有高ASA评分(III和IV),105(11.9%)接受了带或不带造口的肠切除术。死亡率的主要独立预测因素是晚期出现(P=0.003)、全身性腹膜炎(P=0.001)、肠切除术(P=0.000)和高ASA(III和IV)评分(P=.000)。总的来说,死亡率为10.6%。最常见的并发症是伤口感染(39.7%),结论:急诊剖腹手术最常见的指征是阑尾炎,其次是复杂性疝。死亡率的主要独立预测因素包括肠切除、ASA评分高、晚期表现和全身性腹膜炎。
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引用次数: 4
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Journal of Emergency Practice and Trauma
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