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Survival Difference of Colorectal Adenocarcinoma Among Racial and Ethnic Minority Groups: A SEER Database Study. 少数种族和族裔群体结直肠腺癌的生存率差异:SEER 数据库研究。
Q4 Medicine Pub Date : 2024-10-01 DOI: 10.62547/AEBM4307
Arvin Jeremy Tan, Chuong Tran, Nurlan Aliyev, Fedja Rochling, Tomoki Sempokuya

Despite advances in diagnosis and treatment, racial disparities continue to exist in colorectal cancer (CRC) survival. This study aims to characterize the CRC survival differences among racial and ethnic minority groups. The Surveillance, Epidemiology, and End Results (SEER) database was used to identify adults diagnosed with CRC from 2015 to 2019. Demographics, disease characteristics, surgical treatment, stages, and survival data for individuals who are Hispanic, Black, Southeast Asian, Chinese, American Indian and Alaskan Native (AIAN), Asian Indian and Pakistani (AIP), and Native Hawaiian and Other Pacific Islanders (NHOPI) were extracted. Survival analysis was done using the Kaplan-Meier survival curve. Multivariate analysis was done with the Cox proportional hazard model. There were 40 091 individuals with CRC. NHOPI had the youngest median age of 59 years, while Chinese individuals had the oldest median age of 65 years. From the total sample of their respective subgroups, 43.8% of Black patients and 36.7% of AIAN patients had a median household income of <$60 000, while 55.3% of Southeast Asian patients, 59.7% of Chinese patients, 55.8% of AIP patients, and 65.6% of NHOPI patient had a median household income >$70 000. The 1-year survival rate was lower for patients who were Hispanic (62.0%), Black (60.9%), and AIAN (63.1%). Even after multivariate analysis, Black patients had a significant hazard ratio (HR) of 1.21 (95% confidence interval [95% CI]: 1.05-1.38), while AIP had a HR of 0.68 (95% CI 0.55-0.84), compared to AIAN. Other significant variables that were linked with survival included older age, advanced stage of CRC, a median household income <$60 000, male sex, no surgery, subtotal colectomy/hemicolectomy, and total colectomy. Further studies are needed to elucidate the specific causes of these differences and create appropriate strategies to reduce this survival disparity.

尽管在诊断和治疗方面取得了进步,但在结直肠癌(CRC)的存活率方面仍然存在种族差异。本研究旨在描述少数种族和少数族裔群体的结直肠癌存活率差异。研究使用监测、流行病学和最终结果(SEER)数据库来识别 2015 年至 2019 年期间确诊为 CRC 的成年人。提取了西班牙裔、黑人、东南亚裔、华裔、美洲印第安人和阿拉斯加原住民(AIAN)、亚裔印第安人和巴基斯坦人(AIP)以及夏威夷原住民和其他太平洋岛民(NHOPI)的人口统计学、疾病特征、手术治疗、分期和生存数据。采用卡普兰-梅耶生存曲线进行生存分析。多变量分析采用 Cox 比例危险模型。共有 40 091 人患有 CRC。NHOPI 患者的年龄中位数最小,为 59 岁,而中国患者的年龄中位数最大,为 65 岁。在各自亚组的总样本中,43.8% 的黑人患者和 36.7% 的亚裔美国人患者的家庭收入中位数为 70 000 美元。西班牙裔(62.0%)、黑人(60.9%)和亚裔美国人(63.1%)患者的 1 年存活率较低。即使经过多变量分析,黑人患者的危险比(HR)也达到了 1.21(95% 置信区间 [95%CI]:1.05-1.38),而与美国印第安人相比,西班牙裔患者的危险比为 0.68(95% CI 0.55-0.84)。与存活率相关的其他重要变量包括:年龄较大、CRC 晚期、家庭收入中位数
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引用次数: 0
Erratum in: A Rural Community Readiness Assessment of Prehospital Telestroke Services in the Ambulance. 勘误:农村社区救护车院前远程卒中服务准备情况评估》(A Rural Community Readiness Assessment of Prehospital Telestroke Services in the Ambulance)。
Q4 Medicine Pub Date : 2024-10-01

[This corrects the article on p. 250 in vol. 83, PMID: 39290533.].

[此处更正了第 83 卷第 250 页的文章,PMID:39290533]。
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引用次数: 0
Relevance of ACE Scores in Teens with Depression and Anxiety: A Maui Pilot Study. 青少年抑郁和焦虑症患者 ACE 分数的相关性:毛伊岛试点研究
Q4 Medicine Pub Date : 2024-10-01 DOI: 10.62547/TMQN6220
Sharon Wong, Felicitas Livaudais, Meliza Roman, Devashri Prabhudesai, John J Chen

In the aftermath of the Covid pandemic and the notable rise of teen depression and anxiety (DA), there is an urgent need to focus on youth mental health. Another important variable to consider is the presence of adverse childhood experiences (ACE), which can be associated with chronic mental and physical health conditions. This pilot study explores how ACEs relate to DA for adolescents in Maui, Hawai'i. The cohort was 75 patients seen at a Kaiser Pediatric Clinic in the spring of 2022. Data was collected from standard questionnaires and the Pediatric ACEs and Life-Events Screener (PEARLS). There were significant associations between DA and a high ACE score (4+), as well as female sex. A high ACE score can alert providers to initiate a trauma informed dialogue with patients. The effects of trauma are not often discussed at routine visits. Mental health care needs and community support can also be addressed as needed. The PEARLS questionnaire is a standard tool to help clinicians be more trauma-informed. This study explores its relevance at routine adolescent visits.

在科威德(Covid)大流行以及青少年抑郁和焦虑(DA)明显上升之后,我们迫切需要关注青少年的心理健康。另一个需要考虑的重要变量是童年不良经历 (ACE),它可能与慢性身心健康状况有关。这项试点研究探讨了夏威夷毛伊岛青少年的 ACE 与 DA 的关系。研究对象是 2022 年春季在凯泽儿科诊所就诊的 75 名患者。通过标准问卷和儿科ACE和生活事件筛查(PEARLS)收集数据。DA与ACE高分(4分以上)以及女性性别之间存在明显关联。高 ACE 分数可以提醒医疗服务提供者与患者展开创伤知情对话。在常规就诊时,人们并不经常讨论创伤的影响。心理健康护理需求和社区支持也可以根据需要进行讨论。PEARLS 问卷是一种标准工具,可帮助临床医生更好地了解创伤情况。本研究探讨了它与青少年常规就诊的相关性。
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引用次数: 0
A Child with COVID-19 Complicated by Rapidly Progressive Severe Organizing Pneumonia: A Case Report. 一名患有 COVID-19 并发快速进展性严重组织性肺炎的儿童:病例报告。
Q4 Medicine Pub Date : 2024-10-01 DOI: 10.62547/XGJS9690
Tiffany Lau, Anirban Dutta, Prashant J Purohit, Karen Thompson, Kara Yamamoto, Andrew Feng, Timothy Beaty, Marian Melish, Bryscen Prothero, David Kurahara, Brian Wu, Edward Fong, Rodolfo E Bégué

A 2-year-old boy tested positive for SARS-CoV-2 and, after 30 days of mild-moderate respiratory symptoms, suddenly deteriorated and required extracorporeal membrane oxygenation. Lung biopsy was performed with findings consistent with organizing pneumonia. He received intensive therapy with high-dose methylprednisolone, intravenous immune globulin, rituximab, and plasmapheresis without improvement. He died after 85 days hospitalization. This case highlights unique presentations of COVID-19 and reaffirms the concept that, while rare in Hawai'i, pediatric COVID-19 is an ongoing problem and that severe, even fatal, disease can occur.

一名两岁男孩的 SARS-CoV-2 检测呈阳性,在出现轻中度呼吸道症状 30 天后,病情突然恶化,需要进行体外膜氧合。对他进行了肺活检,结果与组织化肺炎一致。他接受了大剂量甲基强的松龙、静脉注射免疫球蛋白、利妥昔单抗和血浆置换等强化治疗,但病情未见好转。住院 85 天后死亡。本病例强调了COVID-19的独特表现形式,并再次证实了一个概念,即虽然小儿COVID-19在夏威夷很罕见,但仍是一个持续存在的问题,而且可能出现严重甚至致命的疾病。
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引用次数: 0
Behind the Smile: Detecting Chronic Kidney Disease Through Oral Health Screenings. 微笑背后通过口腔健康筛查发现慢性肾病。
Q4 Medicine Pub Date : 2024-09-01 DOI: 10.62547/VYCO2960
Patsy Fujimoto, Kamomilani Anduha Wong, Merle Kataoka-Yahiro
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引用次数: 0
Shakuhachi and Haiku Reflection: Their Role in Enhancing Health for Older Adults. 尺八和俳句反思:它们在增进老年人健康方面的作用。
Q4 Medicine Pub Date : 2024-09-01 DOI: 10.62547/WLEQ6493
E Katsumi Takemoto, Yeonjung Jane Lee
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引用次数: 0
A Rural Community Readiness Assessment of Prehospital Telestroke Services in the Ambulance. 农村社区救护车院前远程卒中服务准备情况评估。
Q4 Medicine Pub Date : 2024-09-01 DOI: 10.62547/VZQV6670
Angel Lynn E Talana, Kyrillos B Guirguis, J Aaron Matthews, Pola A Chojecka, Sherita Chapman, Matthew A Koenig

The research team assessed community acceptability of prehospital stroke telemedicine services in rural O'ahu communities. Tools were developed to evaluate patient-centered goals about implementing ambulance-based telemedicine which aimed to retain appropriate patients in community hospitals and improve thrombolytic treatment times. Using a mixed methods approach, the team surveyed well-appearing adults (ie, able to complete survey and interview) at O'ahu community events. Participants were asked to complete a short Likert-scale questionnaire (n=263) followed by a semi-structured interview (n=29). Data were summarized by descriptive and inferential statistics. Comparisons between rural and urban groups were made by chi-square analysis and Wilcoxon rank-sum 2-tailed test. Interviews were transcribed, coded, and analyzed using inductive and deductive methods. The findings suggest that use of prehospital telemedicine for specialty care is viewed favorably by both rural and urban respondents. Additionally, most respondents felt comfortable staying at their local hospital if they had access to a specialist by telemedicine. However, mistrust in rural hospitals may be a potential barrier to implementation. Compared to urban respondents, rural respondents were less confident in their local hospital's resources and capabilities for stroke care. The findings identified a potential misalignment of the project's goal with some patients' goal to use emergency medical services (EMS) to bypass rural hospitals for stroke care. Future community outreach efforts are needed to encourage activation of EMS and highlight the advantages of utilizing prehospital telemedicine for accessing specialty care thereby improving treatment times.

研究小组评估了奥胡岛农村社区对院前中风远程医疗服务的接受程度。开发的工具用于评估以患者为中心的目标,即实施救护车远程医疗,旨在将合适的患者留在社区医院并缩短溶栓治疗时间。研究小组采用混合方法,在欧胡岛社区活动中对形象良好的成年人(即能够完成调查和访谈)进行了调查。受访者被要求填写一份简短的李克特量表问卷(263 人),然后进行一次半结构化访谈(29 人)。数据通过描述性和推论性统计进行总结。农村组和城市组之间的比较采用卡方分析和 Wilcoxon 秩和双尾检验。采用归纳法和演绎法对访谈进行转录、编码和分析。研究结果表明,农村和城市的受访者都对使用院前远程医疗进行专科护理持积极态度。此外,大多数受访者认为,如果能通过远程医疗获得专科医生的诊治,他们可以放心地留在当地医院。然而,对农村医院的不信任可能是实施远程医疗的潜在障碍。与城市受访者相比,农村受访者对当地医院的卒中救治资源和能力信心不足。研究结果发现,该项目目标与部分患者使用紧急医疗服务(EMS)绕过农村医院进行卒中治疗的目标可能存在偏差。今后需要开展社区外联工作,鼓励启动紧急医疗服务,并强调利用院前远程医疗获得专科治疗的优势,从而缩短治疗时间。
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引用次数: 0
A Case Study on the Dietary Shifts in an Older Tongan Migrant to the United States. 关于一位移居美国的汤加老人饮食习惯转变的个案研究。
Q4 Medicine Pub Date : 2024-09-01 DOI: 10.62547/TKOU6982
Victor Kaufusi

This case study, anchored in the Social Ecological Model (SEM), delves into the dietary behaviors of a 67-year-old first-generation Tongan woman in Utah. It uncovers pivotal themes through narrative and thematic analysis: cultural identity, economic constraints, environmental adaptation, and health perceptions. The study underscores the importance of cultural preservation, economic stability, and the centrality of traditional Tongan foods, revealing a complex interplay between cultural adaptation and health awareness. Community support and engagement emerged as crucial in sustaining healthy dietary practices amid cultural changes. The study advocates for an SEM-based framework to guide future research and develop culturally sensitive interventions to improve dietary behaviors among first-generation Tongan immigrants and similar groups and offers valuable insights. The limited generalizability of this study due to its single-case design necessitates future investigations to incorporate broader and more diverse samples to validate the findings and tailor more precise interventions.

本案例研究以社会生态模型(SEM)为基础,深入研究了犹他州一位 67 岁的第一代汤加妇女的饮食行为。它通过叙述和主题分析,揭示了以下关键主题:文化认同、经济限制、环境适应和健康观念。研究强调了文化保护、经济稳定和汤加传统食物中心地位的重要性,揭示了文化适应和健康意识之间复杂的相互作用。社区的支持和参与对于在文化变革中保持健康的饮食习惯至关重要。这项研究提倡采用基于 SEM 的框架来指导未来的研究,并制定对文化敏感的干预措施,以改善第一代汤加移民和类似群体的饮食行为,并提供了宝贵的见解。由于本研究采用的是单例设计,其推广性有限,因此今后的调查需要纳入更广泛、更多样的样本,以验证研究结果,并定制更精确的干预措施。
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引用次数: 0
Nā Kānaka Maoli ma nā 'Āina 'Ē: Exploring Place of Residency as a Native Hawaiian Health Predictor During the COVID-19 Pandemic. Nā Kānaka Maoli ma nā 'Āina 'Ē:探索夏威夷原住民在 COVID-19 大流行期间的健康预测因素。
Q4 Medicine Pub Date : 2024-08-01 DOI: 10.62547/OLHY2267
Dayton K Seto-Myers, Reya H Mokiao, Santino G Camacho, David Huh, Sofie H Aaron, Max A Halvorson, Karina Walters, Michael Spencer

Little is known about the impacts of living in diaspora from the Hawaiian Islands on Native Hawaiian health. To address this, the authors conducted an exploratory analysis using cross-sectional data from the 2021 Native American COVID-19 Alliance Needs Assessment. A total of 1418 participants identified as Native Hawaiian (alone or in any combination), of which 1222 reported residency in the continental US and 196 in Hawai'i. Residency status in the continental US vs Hawai'i was evaluated as a predictor of survey outcomes using likelihood ratio tests on linear and logistic regression models for linear and binary outcomes, respectively. Results showed that NH residency in the continental US was significantly associated with increased odds of reporting fair or poor self-rated health; increased odds for screening positive for anxiety, depression, and suicidality; and increased odds of health insurance loss (P's < .05). Residency in the continent was also associated with lower odds of reporting a diagnosed chronic health condition (P < .05). Residency in the continental US had no observed effect on the odds that participants engaged cultural activities or cultural coping strategies. These results support the role of place of residency as an important Native Hawaiian health predictor during and beyond the COVID-19 pandemic.

人们对散居在夏威夷群岛对夏威夷原住民健康的影响知之甚少。为了解决这个问题,作者利用2021年美国原住民COVID-19联盟需求评估的横截面数据进行了探索性分析。共有1418名参与者被认定为夏威夷原住民(单独或任意组合),其中1222人报告居住在美国大陆,196人居住在夏威夷。通过线性和二元结果的线性回归模型和逻辑回归模型的似然比检验,分别对美国大陆和夏威夷州的居住状况作为调查结果显示的预测因素进行了评估。结果显示,居住在美国大陆的 NH 与报告自我健康状况一般或较差的几率增加、焦虑、抑郁和自杀筛查呈阳性的几率增加以及失去医疗保险的几率增加显著相关(P's < .05)。居住在美国大陆也与报告确诊慢性病的几率较低有关(P<0.05)。居住在美国大陆对参与者参与文化活动或采取文化应对策略的几率没有影响。这些结果支持居住地是夏威夷原住民在COVID-19大流行期间及之后的一个重要健康预测因素。
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引用次数: 0
One Health in Medical Education: A Proposed Framework. 医学教育中的 "一体健康":建议的框架。
Q4 Medicine Pub Date : 2024-08-01 DOI: 10.62547/JVNJ1761
Sameer Kejriwal, ZoeAnn A Kon, Erin T Annick, Carley C Kida, Joshua K Kepler, Jonathan R Carino, Jourdan P McMillan, Sandra P Chang

The One Health concept focuses on the interconnections between human health, animal health, and the environment, stressing the need for interdisciplinary collaborations to address complex issues such as the health challenges posed by climate change and global pandemics. One Health is a central part of the curriculum of veterinary schools, however, it is rarely incorporated into medical school education. Nationally, there are limited examples of formal One Health education and training for medical students. To incorporate One Health into its curriculum, John A. Burns School of Medicine developed a Dean's Certificate of Distinction in One Health that consists of a One Health foundational course, a clinical One Health elective course, participation in the One Health Interest Group, engagement in One Health educational and outreach activities, and a One Health research or curriculum development project. To the authors' knowledge, this is the first One Health certificate program developed and implemented in any Association of American Medical Colleges accredited medical school. Although introducing similar programs into medical curricula will continue to be challenging, we hope it will serve as a framework for other academic institutions.

一体健康 "理念关注人类健康、动物健康和环境之间的相互联系,强调需要跨学科合作来应对气候变化和全球大流行病带来的健康挑战等复杂问题。一体健康 "是兽医学校课程的核心部分,但很少被纳入医学院教育。在全国范围内,对医科学生进行正式的 "一体健康 "教育和培训的例子也很有限。为了将 "一体健康 "纳入课程,约翰伯恩斯医学院开发了 "一体健康 "院长荣誉证书,其中包括一门 "一体健康 "基础课程、一门 "一体健康 "临床选修课程、参加 "一体健康 "兴趣小组、参与 "一体健康 "教育和推广活动,以及一个 "一体健康 "研究或课程开发项目。据作者所知,这是首个在美国医学院协会认证的医学院中开发和实施的 "一体健康 "证书课程。尽管在医学课程中引入类似项目仍将面临挑战,但我们希望它能为其他学术机构提供一个框架。
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引用次数: 0
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Hawai''i journal of health & social welfare
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