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Squamous Cell Carcinoma In Situ (SCCIS) of the Nipple Following Breast Conserving Therapy: Case Report. 乳保乳治疗后乳头原位鳞状细胞癌(SCCIS)一例报告。
Q4 Medicine Pub Date : 2025-08-01 DOI: 10.62547/VCNZ4735
Shirley Cheng, Jared Su, Jessica Kieu, Amelia Wong, Koah Vierkoetter, Ashley Marumoto

Background: Squamous cell carcinoma in situ (SCCIS), also known as Bowen's disease, is a precancerous intradermal lesion that commonly arises in sun-exposed areas. Other risk factors include radiation, inflammation, carcinogen exposure, and human papilloma virus exposure. Its presentation on the nipple-areolar complex is extremely rare with 14 cases reported in literature.

Case presentation: We report a case of a postmenopausal woman with remote history of breast cancer and DCIS treated with bilateral breast conserving surgery followed by adjuvant radiation. She developed SCCIS of the right nipple nearly 30 years later. Associated symptoms included bloody nipple discharge, nipple rash, and nipple pruritus for 1.5 years. A punch biopsy of the right nipple lesion identified epithelioid cells in the intradermal space staining CK7 (+) and p40 (+)/p63 (+), classifying the lesion as Paget's disease. The patient elected to proceed with bilateral mastectomies without reconstruction. Final surgical pathology revealed radiation induced atypia and atypical keratinocytes that focally extend throughout the full epidermal thickness. Immunohistochemical staining demonstrated CK7 (-), CK5/6 (+), p40 (+), HER2 (-) and GCDFP15 (-) consistent with the diagnosis of SCCIS.

Conclusion: Paget's disease of the nipple and SCCIS may present with similar clinical and histopathologic features; however, they are managed differently. Nipple lesions in the setting of prior radiation should raise concern for SCCIS. Clinicians should be aware of this rare, but potential sequelae in patients with a history of breast cancer treated with breast conserving therapy and nipple complaints.

背景:鳞状细胞原位癌(SCCIS),也被称为Bowen病,是一种癌前皮内病变,通常发生在阳光照射的区域。其他危险因素包括辐射、炎症、致癌物暴露和人类乳头瘤病毒暴露。其表现在乳头-乳晕复合体是极其罕见的,文献报道14例。病例介绍:我们报告了一例绝经后的妇女,有乳腺癌和DCIS的长期病史,接受双侧保乳手术和辅助放疗。近30年后,她患上了右乳头SCCIS。相关症状包括乳头溢血、乳头皮疹和乳头瘙痒,持续时间为1.5年。右乳头病变穿孔活检发现皮内间隙上皮样细胞染色CK7(+)和p40 (+)/p63(+),分类为Paget病。患者选择继续进行双侧乳房切除术而不进行重建。最终手术病理显示放射诱导的非典型性和非典型性角化细胞局部延伸到整个表皮厚度。免疫组化染色显示CK7(-)、CK5/6(+)、p40(+)、HER2(-)和GCDFP15(-)与SCCIS的诊断一致。结论:乳头Paget病与SCCIS可能具有相似的临床和组织病理特征;然而,它们的管理方式不同。既往放疗的乳头病变应引起对SCCIS的关注。临床医生应该意识到这种罕见的,但潜在的后遗症的乳腺癌患者的历史,乳房保留治疗和乳头投诉。
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引用次数: 0
Importance of Building the Public Health Workforce: Commentary by the Hawai'i Public Health Infrastructure Grant Workforce Director to Introduce the Special Issue on Public Health Workforce Development in Hawai'i. 建设公共卫生人力的重要性:夏威夷公共卫生基础设施拨款人力主任介绍夏威夷公共卫生人力发展特刊的评论。
Q4 Medicine Pub Date : 2025-07-01 DOI: 10.62547/CWGK9452
Scott Murakami
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引用次数: 0
An Evaluation of the Native Hawaiian and Indigenous Health Summer Health Academy. 夏威夷原住民健康与原住民健康暑期学院之评估。
Q4 Medicine Pub Date : 2025-07-01 DOI: 10.62547/JVEP6407
Mapuana C K Antonio, Yasmeen Latore, Samantha Keaulana, Ashlea Gillon, Nicole Cristobal, Amber Granite, Silvera Erari, Pauline Mcfall, Māhealani Taitague-Laforga, Naneaokeola Siu, Ki'ilaweau Aweau, Daniel Gracia, Jane J Chung-Do

Indigenous ways of knowing center on balance and holism, with an emphasis of learning through ancestral and intergenerational knowledge, which continue to be revitalized as a demonstration of the ongoing resilience of Indigenous Peoples. The Native Hawaiian and Indigenous Health (NHIH) Summer Health Academy (SHA) program was developed and implemented with an objective of increasing diversity, equity, and inclusion in higher education, fostering relationships at multiple levels, addressing gaps in education and academia, preparing students to work with and for Native and Indigenous communities, and changing the narrative of health and healing to better align with Native Hawaiian and Indigenous worldviews of health. Program activities included individualized mentoring, critical self-reflections through activities such as Indigenous photovoice, experiential opportunities to learn about social determinants of health, and community-engaged research projects. Overarching themes from the critical self-reflections included holistic and relational health, the importance of 'ohana (family), intergenerational relationships, and thriving 'Āina (land) as thriving health. Results of the pre and post-test surveys demonstrated the promise and success of the NHIH SHA course, with a statistically significant change in knowledge related to cultural humility, community-based research, Indigenous methodologies, and Indigenous frameworks of health. This program demonstrates the importance of creating a pathway of success for Native Hawaiian and Indigenous students to address gaps and disparities in higher education for Native Hawaiian and Indigenous communities at large, while increasing the pursuit of health-related fields by Native Hawaiian and other Indigenous students.

土著的认知方式以平衡和整体主义为中心,强调通过祖传和代际知识进行学习,这些知识不断得到振兴,证明了土著人民的持续复原力。夏威夷土著和土著健康(NHIH)暑期健康学院(SHA)计划的制定和实施目标是增加高等教育的多样性、公平性和包容性,促进多层次的关系,解决教育和学术界的差距,为学生与土著和土著社区合作做好准备,并改变健康和治疗的叙述,以更好地与夏威夷土著和土著的健康世界观保持一致。方案活动包括个体化指导、通过土著photovoice等活动进行批判性自我反思、了解健康的社会决定因素的体验机会以及社区参与的研究项目。批判性自我反思的主要主题包括整体和关系健康,“ohana”(家庭)的重要性,代际关系,以及“Āina”(土地)作为蓬勃发展的健康。测试前和测试后调查的结果表明,NHIH健康与卫生课程的前景和成功,在与文化谦逊、社区研究、土著方法和土著健康框架相关的知识方面发生了统计上显著的变化。该项目表明,为夏威夷原住民和土著学生开辟一条通往成功之路的重要性,以解决夏威夷原住民和整个土著社区在高等教育中的差距和差距,同时增加夏威夷原住民和其他土著学生对健康相关领域的追求。
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引用次数: 0
The Environmental Health Workforce in Hawai'i: Current Status and Recommendations for Improvement. 夏威夷环境卫生工作人员:现状和改进建议。
Q4 Medicine Pub Date : 2025-07-01 DOI: 10.62547/WXTF9814
Rosana Hernández Weldon, Catherine Pirkle

Environmental health (EH) is a critical branch of public health that addresses current and emerging health threats related to issues such as climate change and pollution. The state of Hawai'i faces distinct EH challenges, including air pollution from volcanic activity, widespread vulnerability to sea level rise, wildfire, exposure to pollution from accidental spills from military sites, and a tropical environment that contributes to heat-related illness and that is conducive to mosquito-borne illnesses. A robust EH workforce is essential to respond to these concerns. This article uses a combination of targeted literature review and qualitative interview methods to synthesize evidence relevant to the issue for the state of Hawai'i. Such a workforce includes professionals in state and federal agencies, academia, and the non-profit and community sectors. Many academic disciplines and professionals can contribute to the EH workforce, including environmental scientists and epidemiologists, toxicologists, exposure assessment scientists, risk characterization scientists, environmental policy and communication experts and community-based EH workers. Currently, there is an insufficient EH workforce in Hawai'i and addressing this gap will require strategic investments in academia and the Hawai'i Department of Health, as well as expanded collaboration. Training programs are also critical, in particular cross-sector ones. Finally, a proficient EH workforce in Hawai'i needs to be able to communicate effectively with the diverse populations of the state and demonstrate commitment to and understanding of the unique populations of the state and their EH concerns.

环境卫生是公共卫生的一个重要分支,处理与气候变化和污染等问题有关的当前和新出现的健康威胁。夏威夷州面临着独特的EH挑战,包括火山活动造成的空气污染、对海平面上升的普遍脆弱性、野火、军事场所意外泄漏造成的污染,以及导致热相关疾病和蚊子传播疾病的热带环境。强大的EH工作队伍对于应对这些问题至关重要。本文采用有针对性的文献综述和定性访谈相结合的方法来合成与夏威夷州问题相关的证据。这样的劳动力队伍包括州和联邦机构、学术界、非营利组织和社区部门的专业人员。许多学科和专业人员可以为环境卫生工作者做出贡献,包括环境科学家和流行病学家、毒理学家、暴露评估科学家、风险表征科学家、环境政策和沟通专家以及社区环境卫生工作者。目前,夏威夷的卫生保健工作人员不足,解决这一差距需要对学术界和夏威夷卫生部进行战略投资,并扩大合作。培训项目也很重要,尤其是跨部门培训项目。最后,在夏威夷,一个熟练的EH工作人员需要能够有效地与该州不同的人口进行沟通,并表现出对该州独特人口及其EH关注点的承诺和理解。
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引用次数: 0
Assuring the "Public" in "Public Health": Developing Workforce Capacity, Diversity, and Connectedness at the Department of Public Health Sciences. 确保“公共卫生”中的“公众”:在公共卫生科学系发展劳动力能力、多样性和连通性。
Q4 Medicine Pub Date : 2025-07-01 DOI: 10.62547/DJUU3671
Jeanelle Sugimoto-Matsuda, Denise C Nelson-Hurwitz, Jane J Chung-Do, Mapuana C K Antonio, Elizabeth McFarlane, Eric Hurwitz, Kathryn L Braun

Public Health serves a critical role in ensuring and maintaining population health by recognizing that health is influenced by individual, social, economic, environmental, structural, and political factors. Despite the core role that public health plays in communities, the field's workforce faces shortages which were already dire pre-pandemic. The Department of Public Health Sciences (DPHS) at the University of Hawai'i at Mānoa (UHM) provides bachelor, masters, and doctoral degrees and serves as an essential training ground for the public health workforce in Hawai'i. The purpose of this paper is to describe some of the ways DPHS is meeting the ever-growing demand for qualified health professionals, in local and global government and community health departments and organizations. Since the first graduating class in 1967, more than 7000 individuals have earned accredited degrees through DPHS, including over 500 diverse undergraduate and graduate alumni since Fall 2015. The quality of DPHS' program and instruction are consistently highly rated by students and alumni. The curriculum is continually enhanced through innovative programs, and actively engages students in advancing public health practice and gaining applied research skills through all steps of scholarship including publications. DPHS is proud to be part of the movement towards building and revitalizing the public health workforce through teaching, research, and service and continues to strive to foster practitioners who will represent and serve local communities, engage in meaningful research and service, and bridge connections across disciplines and geographies.

公共卫生认识到健康受到个人、社会、经济、环境、结构和政治因素的影响,在确保和维持人口健康方面发挥着关键作用。尽管公共卫生在社区中发挥着核心作用,但该领域的工作人员面临着大流行前已经严重短缺的问题。夏威夷大学公共卫生科学系(DPHS)在Mānoa (UHM)提供学士、硕士和博士学位,是夏威夷公共卫生工作人员的重要培训基地。本文的目的是描述DPHS在地方和全球政府以及社区卫生部门和组织中满足对合格卫生专业人员不断增长的需求的一些方法。自1967年第一届毕业班以来,超过7000人通过DPHS获得了认可的学位,其中包括自2015年秋季以来500多名不同的本科生和研究生校友。DPHS的课程和教学质量一直受到学生和校友的高度评价。课程通过创新项目不断加强,并积极参与学生推进公共卫生实践,并通过包括出版物在内的所有奖学金步骤获得应用研究技能。DPHS自豪地成为通过教学、研究和服务建设和振兴公共卫生人力的运动的一部分,并继续努力培养代表和服务当地社区的从业人员,从事有意义的研究和服务,并跨越学科和地域建立联系。
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引用次数: 0
Strategies for Building a Dementia-Capable Workforce in Hawai'i. 在夏威夷建立有能力的痴呆症劳动力的战略。
Q4 Medicine Pub Date : 2025-07-01 DOI: 10.62547/IYAX3749
Christy Nishita, Kevin Y Kawamoto

Health care workers with specialized knowledge and skills to work with people living with symptoms of dementia are needed in all sectors of the health care industry in Hawai'i as the number of people in the population diagnosed with Alzheimer's disease and related dementias (ADRD) is expected to increase along with the overall number of older adults (ages 65+). This article provides a scoping review of relevant population data that suggest an urgency to address this need even as the state contends with an overall shortage of workers throughout the public health and health care industry. The authors then provide practical solutions, recommending a multi-pronged approach to introduce or enhance dementia-care competencies at various levels of education - from high school to graduate or professional studies - and through continuing education and professional development programs for practicing health professionals. Consistent with the public health philosophy of health equity, the authors propose that providing quality care to persons living with dementia is a social justice goal that can be achieved through this multi-pronged approach.

夏威夷卫生保健行业的所有部门都需要具有专门知识和技能的卫生保健工作者,以便与患有痴呆症症状的人一起工作,因为预计人口中被诊断患有阿尔茨海默病和相关痴呆症(ADRD)的人数将随着老年人(65岁以上)的总数而增加。本文对相关人口数据进行了范围审查,表明即使在整个公共卫生和医疗保健行业面临工人总体短缺的情况下,也迫切需要解决这一需求。然后,作者提供了切实可行的解决方案,推荐了一种多管齐下的方法,在各个教育层次(从高中到研究生或专业学习)引入或提高痴呆症护理能力,并通过对执业卫生专业人员的继续教育和专业发展计划。与健康公平的公共卫生理念相一致,作者提出,为痴呆症患者提供高质量的护理是一个社会正义的目标,可以通过这种多管齐下的方法来实现。
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引用次数: 0
Issue Overview: Public Health Workforce Development in Hawai'i: Building a Post Pandemic Future to Achieve Health Equity. 问题概述:夏威夷公共卫生人力发展:建立大流行后的未来以实现卫生公平。
Q4 Medicine Pub Date : 2025-07-01 DOI: 10.62547/TTGY5303
Tetine Sentell, Lola Irvin, Rebekah Rodericks, Jordan Marshall
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引用次数: 0
Quantifying the Public Health Workforce for Hawai'i: Current Data, Measurement Complexities, and Conceptual Frameworks for Next Steps. 量化夏威夷的公共卫生人力:当前数据、测量复杂性和下一步的概念框架。
Q4 Medicine Pub Date : 2025-07-01 DOI: 10.62547/HRNZ2940
Tetine Sentell, Janet M Berreman, Laura Reichhardt, Aimee Grace, Jessica Yamauchi, Jordan Marshall, Kelley Withy

The public health workforce is critical to community well-being and too often overlooked. The goal of public health is to prevent disease, promote health, and protect the public from current and emerging health threats. This work is vital to the health, safety, security, and prosperity of all communities and requires an adequate workforce. Despite the well-articulated gaps in the clinical health care workforce, Hawai'i's public health workforce needs and capacities are not as well understood. Public health workforce enumeration is complex. The field lacks a consistent definition of its full workforce and agreed-upon mechanisms for measuring it. Resolving these issues is an active area of scholarship and action, particularly given the COVID-19 pandemic-induced workforce capacity strain. This article reviews existing literature on public health workforce enumeration as a step toward filling this knowledge gap for practical use in the state of Hawai'i. Specifically, using a critical literature review method, this article (1) consolidates existing data about Hawai'i's public health workforce, (2) summarizes public health workforce measurement challenges, (3) shares existing frameworks and models for quantifying the public health workforce, and (4) discusses next steps to provide actionable information for ensuring Hawai'i's public health workforce can fulfill its mission. The article confirms that core public health functions as articulated in the (a) updated 10 Essential Public Health Services framework and (b) Foundational Public Health Services framework provide useful guidance for public health workforce enumeration in Hawai'i. The article also concludes that the US Department of Health and Human Services (HHS) definition of public health workers provides comprehensive framing for this enumeration. Based on this literature synthesis, a descriptive figure of the public health workforce in Hawai'i was developed to guide future work and prioritization.

公共卫生人力对社区福祉至关重要,但往往被忽视。公共卫生的目标是预防疾病,促进健康,保护公众免受当前和新出现的健康威胁。这项工作对所有社区的健康、安全、保障和繁荣至关重要,需要充足的劳动力。尽管临床卫生保健人力存在明显的差距,但夏威夷的公共卫生人力需求和能力并没有得到很好的了解。公共卫生工作人员的枚举是复杂的。该领域缺乏对其全部劳动力的一致定义和商定的衡量机制。解决这些问题是一个活跃的学术和行动领域,特别是考虑到COVID-19大流行导致的劳动力能力紧张。本文回顾了关于公共卫生工作人员枚举的现有文献,作为填补这一知识空白的一步,以便在夏威士州实际使用。具体而言,本文采用关键的文献综述方法,(1)整合了有关夏威夷公共卫生人力的现有数据,(2)总结了公共卫生人力测量面临的挑战,(3)分享了量化公共卫生人力的现有框架和模型,(4)讨论了为确保夏威夷公共卫生人力能够履行其使命提供可操作信息的下一步措施。文章确认,(a)更新后的10项基本公共卫生服务框架和(b)基础公共卫生服务框架中阐明的核心公共卫生职能为夏威夷公共卫生工作人员的枚举提供了有用的指导。文章还得出结论,美国卫生与公众服务部(HHS)对公共卫生工作者的定义为这一列举提供了全面的框架。在此文献综合的基础上,制定了夏威夷公共卫生工作人员的描述性数字,以指导未来的工作和优先次序。
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引用次数: 0
Guest Editors' Message: Hawai'i's Public Health Workforce. 客座编辑的信息:夏威夷的公共卫生工作者。
Q4 Medicine Pub Date : 2025-07-01 DOI: 10.62547/RMGI1840
Tetine Sentell, Lola Irvin, Rebekah Rodericks, Jordan Marshall, May Rose Dela Cruz, Donna-Marie Palakiko, Jessica Yamauchi, Laura Reichhardt, Camonia Graham-Tutt, Janet Berreman, Lance Ching, Kelley Withy, Alden Henderson, Simone Schmid, Eric Hurwitz, Jermy Domingo
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引用次数: 0
Building the Future of Public Health Workforce: Comprehensive Internship Program at Hawai'i Public Health Institute. 建设公共卫生人力的未来:夏威夷公共卫生研究所的综合实习计划。
Q4 Medicine Pub Date : 2025-07-01 DOI: 10.62547/FLOJ3448
Rie Kuhaulua, Jessica Yamauchi

The United States public health workforce is facing a critical shortage, with a significant exodus of professionals from state and local health departments. This column discusses the importance of internship programs in developing a sustainable pipeline for new generations of public health professionals. The Hawai'i Public Health Institute's internship program is examined as an example to provide insights for organizations seeking to establish or enhance their internship programs. From 2020 to 2023, HIPHI received 258 applications and accepted 119 interns, with an acceptance rate of 46%. Interns were mostly bachelor's level students (69%), followed by master's level students (24%). Most interns (66%) were public health majors, with others from related fields. The program offered diverse placements across various public health areas and provided training opportunities including orientation, webinars, and field excursions. Recommendations for workforce development include fostering stakeholder collaboration, supporting practicum host sites and job supervisors, sharing information and best practices, and promoting leadership development. A holistic strategy involving stakeholder collaboration, leadership development, evaluation, and ongoing workforce assessment is essential for developing a robust public health workforce capable of promoting health, preventing disease, reducing mortality, and responding effectively to future crises. Program evaluation is a necessary next step to understand how best to assist interns and early career professionals during their practicums.

美国公共卫生工作人员正面临严重短缺,州和地方卫生部门的专业人员大量外流。本专栏讨论了实习项目在培养新一代公共卫生专业人员方面的重要性。夏威夷公共卫生研究所的实习计划作为一个例子,为寻求建立或加强实习计划的组织提供见解。从2020年到2023年,HIPHI收到258份申请,接受119名实习生,录取率为46%。实习生主要是本科学生(69%),其次是硕士学生(24%)。大多数实习生(66%)是公共卫生专业的,其他人来自相关领域。该项目在不同的公共卫生领域提供了不同的实习机会,并提供了培训机会,包括定向培训、网络研讨会和实地考察。关于劳动力发展的建议包括促进利益相关者合作,支持实习地点和工作主管,分享信息和最佳实践,促进领导力发展。一项涉及利益攸关方协作、领导力发展、评价和持续工作人员评估的整体战略,对于发展一支能够促进健康、预防疾病、降低死亡率和有效应对未来危机的强大公共卫生工作队伍至关重要。项目评估是了解如何在实习期间最好地帮助实习生和早期职业专业人员的必要步骤。
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引用次数: 0
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Hawai''i journal of health & social welfare
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