Laura Silva Paranhos, Pedro Alves Soares Vaz de Castro, Giovanna Rotondo de Araújo, Fernanda Do Carmo Magalhães, Juliana Maria Trindade Bezerra
Tungiasis is a neglected parasitic disease caused by penetration of female Tunga penetrans under the skin, causing important health outcomes in humans. Therefore, the aim of this study was to describe the prevalence of tungiasis in Brazil and in its federative units. In November 2019, an investigation was carried out to find studies published from 1980 onwards in MEDLINE, LILACS, Cochrane, CINAHL, Scopus, Web of Science and Embase databases, and in the gray literature, using descriptors related to the prevalence of tungiasis caused by T. penetrans in Brazil. Of the 542 studies found, only 16 published between 2002 and 2010 met the eligibility criteria to be included in this systematic review. Of the 16 selected publications, 14 addressed the prevalence of tungiasis in communities in the Northeast region of the country, one in the South and one in the Southeast. The general prevalence of the parasitosis in the studies ranged from 1.6% to 54.8%, predominantly in the five to nine age group. Eight studies considered the prevalence by gender, ranging from 2.2% to 62.2% for females and 1.1% to 62.5% for males. This systematic review presents an unprecedented survey of the prevalence of tungiasis, a parasitic disease whose dissemination is facilitated by several factors, occuring mainly in low-income communities. Considering the regionalization of the findings, the scarcity of publications, as well as disease neglect, more studies are required. KEY WORDS: Tunga penetrans; occurrence; epidemiology; PRISMA; human.
通虫病是一种被忽视的寄生虫病，由雌性通虫虫在皮肤下渗透引起，对人类造成重要的健康后果。因此，本研究的目的是描述通虫病在巴西及其联邦单位的流行情况。2019年11月，研究人员开展了一项调查，查找1980年以来在MEDLINE、LILACS、Cochrane、CINAHL、Scopus、Web of Science和Embase数据库以及灰色文献中发表的研究，这些研究使用了与巴西由T. penetrans引起的通线虫病流行相关的描述词。在发现的542项研究中，2002年至2010年间发表的只有16项符合纳入本系统评价的资格标准。在所选的16份出版物中，有14份涉及该国东北部地区、南部和东南部各社区的东突病流行情况。研究中寄生虫病的总体流行率为1.6%至54.8%，主要发生在5至9岁年龄组。8项研究按性别考虑患病率，女性为2.2%至62.2%，男性为1.1%至62.5%。这一系统综述对通虫病的流行情况进行了前所未有的调查。通虫病是一种寄生虫病，其传播受到若干因素的促进，主要发生在低收入社区。考虑到研究结果的区域化、出版物的稀缺性以及对疾病的忽视，需要进行更多的研究。关键词:钨渗透器;发生;流行病学;棱镜;人类。
{"title":"Prevalence of tungiasis in humans in Brazil and in its federative units: a systematic review","authors":"Laura Silva Paranhos, Pedro Alves Soares Vaz de Castro, Giovanna Rotondo de Araújo, Fernanda Do Carmo Magalhães, Juliana Maria Trindade Bezerra","doi":"10.5216/rpt.v51i1.70027","DOIUrl":"https://doi.org/10.5216/rpt.v51i1.70027","url":null,"abstract":"Tungiasis is a neglected parasitic disease caused by penetration of female Tunga penetrans under the skin, causing important health outcomes in humans. Therefore, the aim of this study was to describe the prevalence of tungiasis in Brazil and in its federative units. In November 2019, an investigation was carried out to find studies published from 1980 onwards in MEDLINE, LILACS, Cochrane, CINAHL, Scopus, Web of Science and Embase databases, and in the gray literature, using descriptors related to the prevalence of tungiasis caused by T. penetrans in Brazil. Of the 542 studies found, only 16 published between 2002 and 2010 met the eligibility criteria to be included in this systematic review. Of the 16 selected publications, 14 addressed the prevalence of tungiasis in communities in the Northeast region of the country, one in the South and one in the Southeast. The general prevalence of the parasitosis in the studies ranged from 1.6% to 54.8%, predominantly in the five to nine age group. Eight studies considered the prevalence by gender, ranging from 2.2% to 62.2% for females and 1.1% to 62.5% for males. This systematic review presents an unprecedented survey of the prevalence of tungiasis, a parasitic disease whose dissemination is facilitated by several factors, occuring mainly in low-income communities. Considering the regionalization of the findings, the scarcity of publications, as well as disease neglect, more studies are required.\u0000KEY WORDS: Tunga penetrans; occurrence; epidemiology; PRISMA; human.","PeriodicalId":36789,"journal":{"name":"Journal of Tropical Pathology","volume":"15 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-04-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90829075","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
João Victor Ferreira Trindade, Lis Alves Ferrareis, Ana Karolina Carvalho de Andrade, Julia De Moraes Scopel Borges, Stefânia Salvador Pereira Montenegro, Bruna Soares de Souza Lima Rodrigues, Paulo Sérgio Balbino Miguel, R. Siqueira-Batista
Spider envenomation, generically known as arachnidism, is described in many places around the world. In terms of medical importance, the following genera of animals stand out as the main origin of the morbid condition: Atrax (Sidney funnel web spider), Steatoda (false black widow), Latrodectus (black widow), Loxosceles (brown spider) and Phoneutria (armed spider), the last three causing accidents involving spiders in Brazil. This article, part 1 of 2, aims to present the main aspects of arachnidism in the country, with an emphasis on the biology and geographical distribution of spiders, biochemistry of the venom, pathogenesis and epidemiology of arachnidism, as well as prevention of the morbid condition. KEY WORDS: Arachnidism; araneae; spider bites; spider venoms.
{"title":"Spiders in Brazil: from arachnidism to potential therapeutic use of their venom part 1 of 2","authors":"João Victor Ferreira Trindade, Lis Alves Ferrareis, Ana Karolina Carvalho de Andrade, Julia De Moraes Scopel Borges, Stefânia Salvador Pereira Montenegro, Bruna Soares de Souza Lima Rodrigues, Paulo Sérgio Balbino Miguel, R. Siqueira-Batista","doi":"10.5216/rpt.v51i1.67446","DOIUrl":"https://doi.org/10.5216/rpt.v51i1.67446","url":null,"abstract":"Spider envenomation, generically known as arachnidism, is described in many places around the world. In terms of medical importance, the following genera of animals stand out as the main origin of the morbid condition: Atrax (Sidney funnel web spider), Steatoda (false black widow), Latrodectus (black widow), Loxosceles (brown spider) and Phoneutria (armed spider), the last three causing accidents involving spiders in Brazil. This article, part 1 of 2, aims to present the main aspects of arachnidism in the country, with an emphasis on the biology and geographical distribution of spiders, biochemistry of the venom, pathogenesis and epidemiology of arachnidism, as well as prevention of the morbid condition.\u0000KEY WORDS: Arachnidism; araneae; spider bites; spider venoms.","PeriodicalId":36789,"journal":{"name":"Journal of Tropical Pathology","volume":"72 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-04-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86335130","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dulio Walter Morales-Villanueva, Franklin Sullca-Ccopa, L. Gonzales-Huerta, B. Dámaso-Mata, V. Panduro-Correa, J. L. Maguiña, S. Pecho-Silva, A. Rodríguez-Morales, Walter Gómez-Gonzales, K. Arteaga-Livias
Dengue is a worldwide spread arboviral disease. Huánuco region is an endemic area for dengue. Understanding the influence of Knowledge, Attitudes and Practices (KAP) in dengue endemic areas can provide important insight for improving public health policies. The purpose of this study was to understand the KAP about dengue in the marginal urban city of Tingo Maria, district of Rupa-Rupa, a rain forest area in Huánuco region and its association with positive serology for dengue. An analytical, retrospective, cross-sectional study was carried out in which a randomized sample of 112 people were evaluated using a semi structured questionnaire and tested for IgG against dengue virus. Most participants recruited were from marginal urban settlements. The median age was 38 years and 64% were female. A bivariate analysis showed an association between educational level and serological positivity. Over 95% of participants with only primary school education had a positive serological test for dengue. No statistical significances were found between attitudes towards dengue control initiatives (p=0.221), preventive practices against dengue (p=0.773), and the level of knowledge about dengue (p=0.073). Although attitudes, preventive practices and level of knowledge were not related to positive serology in dengue cases, educational level showed an association with serological positivity for dengue. KEY WORDS: Dengue; knowledge; attitude; practice; education; Peru.
{"title":"Educational level and positive serology for dengue. a knowledge, attitudes and practices study in Huánuco, Peru","authors":"Dulio Walter Morales-Villanueva, Franklin Sullca-Ccopa, L. Gonzales-Huerta, B. Dámaso-Mata, V. Panduro-Correa, J. L. Maguiña, S. Pecho-Silva, A. Rodríguez-Morales, Walter Gómez-Gonzales, K. Arteaga-Livias","doi":"10.5216/rpt.v51i1.70543","DOIUrl":"https://doi.org/10.5216/rpt.v51i1.70543","url":null,"abstract":"Dengue is a worldwide spread arboviral disease. Huánuco region is an endemic area for dengue. Understanding the influence of Knowledge, Attitudes and Practices (KAP) in dengue endemic areas can provide important insight for improving public health policies. The purpose of this study was to understand the KAP about dengue in the marginal urban city of Tingo Maria, district of Rupa-Rupa, a rain forest area in Huánuco region and its association with positive serology for dengue. An analytical, retrospective, cross-sectional study was carried out in which a randomized sample of 112 people were evaluated using a semi structured questionnaire and tested for IgG against dengue virus. Most participants recruited were from marginal urban settlements. The median age was 38 years and 64% were female. A bivariate analysis showed an association between educational level and serological positivity. Over 95% of participants with only primary school education had a positive serological test for dengue. No statistical significances were found between attitudes towards dengue control initiatives (p=0.221), preventive practices against dengue (p=0.773), and the level of knowledge about dengue (p=0.073). Although attitudes, preventive practices and level of knowledge were not related to positive serology in dengue cases, educational level showed an association with serological positivity for dengue.\u0000KEY WORDS: Dengue; knowledge; attitude; practice; education; Peru.","PeriodicalId":36789,"journal":{"name":"Journal of Tropical Pathology","volume":"108 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87003754","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Amanda Silva de Oliveira (§), César Gómez-Hernández (§), Karine Rezende-Oliveira
ABSTRACT Balantidiasis, a disease caused by the ciliated protozoan Balantidium coli, mainly infects thelarge intestine and may present intestinal spread. The purpose of this literature review was to study the infection by B. coli and comorbidities to identify the factors that can contribute to the establishment of the disease. In this review, we attempt to explore and describe the various comorbidities associated with B. coli infection. We reviewed the literature based on comorbidities with a focus on the association with B. coli infection. The primary platforms targeted were PubMed, LILACS, SciELO and Google Scholar. Studies published between 1990 and 2020 in Portuguese, English, and Spanish were considered. The comorbidities reported in the papers were diverse, associating infection by B. coli with the immunosuppression that they generate. The intestinal microbiota may also play an important role, because when dysbiosis is present, its composition and structure are affected, which may enable the invasion of the mucosa. The review shows that the presence of the parasite and establishment of balantidiasis can influence in the clinical stage of chronic and autoimmune diseases, considering themodulation of the immune response in presence of B. coli.KEY WORDS: Balantidium coli; autoimmunity; balantidiosis; comorbidities; immunodepression.
{"title":"BALANTIDIUM COLI infection, immune status and comorbidities: literature review","authors":"Amanda Silva de Oliveira (§), César Gómez-Hernández (§), Karine Rezende-Oliveira","doi":"10.5216/rpt.v50i4.70600","DOIUrl":"https://doi.org/10.5216/rpt.v50i4.70600","url":null,"abstract":"ABSTRACT Balantidiasis, a disease caused by the ciliated protozoan Balantidium coli, mainly infects thelarge intestine and may present intestinal spread. The purpose of this literature review was to study the infection by B. coli and comorbidities to identify the factors that can contribute to the establishment of the disease. In this review, we attempt to explore and describe the various comorbidities associated with B. coli infection. We reviewed the literature based on comorbidities with a focus on the association with B. coli infection. The primary platforms targeted were PubMed, LILACS, SciELO and Google Scholar. Studies published between 1990 and 2020 in Portuguese, English, and Spanish were considered. The comorbidities reported in the papers were diverse, associating infection by B. coli with the immunosuppression that they generate. The intestinal microbiota may also play an important role, because when dysbiosis is present, its composition and structure are affected, which may enable the invasion of the mucosa. The review shows that the presence of the parasite and establishment of balantidiasis can influence in the clinical stage of chronic and autoimmune diseases, considering themodulation of the immune response in presence of B. coli.KEY WORDS: Balantidium coli; autoimmunity; balantidiosis; comorbidities; immunodepression.","PeriodicalId":36789,"journal":{"name":"Journal of Tropical Pathology","volume":"27 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85332709","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
*Presented at the ”Consultative Meeting on the Strategic and Operational Aspects for the Clinical Development of Trypanocidal Drugs for Chagas Disease, 23-24 April 2007, Buenos Aires, Argentina.”, sponsored by TDR, WHO. This publication is dedicated to one of the authors (deceased) due to his life dedicated to Chagas disease and particularly to this subject. After 14 years, this material is still valid.
{"title":"Chagas disease. The use of serology to establish drug efficacy. Value and limitations*","authors":"Alejandro O. Luquetti, A. Rassi","doi":"10.5216/rpt.v50i4.71556","DOIUrl":"https://doi.org/10.5216/rpt.v50i4.71556","url":null,"abstract":"*Presented at the ”Consultative Meeting on the Strategic and Operational Aspects for the Clinical Development of Trypanocidal Drugs for Chagas Disease, 23-24 April 2007, Buenos Aires, Argentina.”, sponsored by TDR, WHO.\u0000This publication is dedicated to one of the authors (deceased) due to his life dedicated to Chagas disease and particularly to this subject. After 14 years, this material is still valid.","PeriodicalId":36789,"journal":{"name":"Journal of Tropical Pathology","volume":"85 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85372649","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jonathan Da Fraga Santana, Lucas Martins da Silva, Filipe Valdino Ferreira Pereira, Bruno Ferreira Amorim, Paulo Vitor Pimentel, Mariana Do Rosário Souza, Caique Jordan Nunes Ribeiro, Allan Dantas dos Santos, P. Lima dos Santos, Débora Dos Santos Tavares, M. Bezerra-Santos
Schistosomiasis is still a serious public health concern in Brazil and Sergipe State presents the highest prevalence rate of the disease. Brazil implemented the Schistosomiasis Control Program (PCE) with several strategies to control the disease, including health education actions in endemic areas. Herein, we assessed the impact of an educational intervention on knowledge concerning schistosomiasis in students from a riverside village of Sergipe, Northeastern Brazil. The study was carried out in 3 phases. 1) A questionnaire was applied to assess the students’ knowledge about the biological, clinical, and epidemiological aspects of schistosomiasis mansoni (pre-test). 2) Next, an educational intervention was conducted. Pamphlets about schistosomiasis were distributed to the entire school community, who were then invited to a lecture. 3) A post-test was performed using the questionnaire to assess acquired knowledge. 151 elementary school students were interviewed. 2.6% of the pre-test students and 4.3% of the post-test group had already been diagnosed with schistosomiasis. In the pre-test, only 24.5% knew the cause of the disease and 48.3% the transmission sites. In the post-test, 74.3% (OR= 8.9; p-value<0.0001) knew the etiology and 77.1% the possible transmission sites (OR= 3.6; p-value<0.0001). There was also significant improvement in knowledge regarding signs, symptoms and prophylactic measures. Most students were unaware of the risk of reinfection by Schistosoma mansoni after treatment. The educational intervention proved quite effective in increasing information on schistosomiasis. These results reinforce the importance of health education as an auxiliary tool in the control of schistosomiasis. KEY WORDS: Schistosomiasis mansoni; health education; schoolchildren; neglected tropical diseases; Brazil.
{"title":"Educational intervention on scholar’s knowledge regarding schistosomiasis in a riverside community, northeastern Brazil","authors":"Jonathan Da Fraga Santana, Lucas Martins da Silva, Filipe Valdino Ferreira Pereira, Bruno Ferreira Amorim, Paulo Vitor Pimentel, Mariana Do Rosário Souza, Caique Jordan Nunes Ribeiro, Allan Dantas dos Santos, P. Lima dos Santos, Débora Dos Santos Tavares, M. Bezerra-Santos","doi":"10.5216/rpt.v50i4.70468","DOIUrl":"https://doi.org/10.5216/rpt.v50i4.70468","url":null,"abstract":"Schistosomiasis is still a serious public health concern in Brazil and Sergipe State presents the highest prevalence rate of the disease. Brazil implemented the Schistosomiasis Control Program (PCE) with several strategies to control the disease, including health education actions in endemic areas. Herein, we assessed the impact of an educational intervention on knowledge concerning schistosomiasis in students from a riverside village of Sergipe, Northeastern Brazil. The study was carried out in 3 phases. 1) A questionnaire was applied to assess the students’ knowledge about the biological, clinical, and epidemiological aspects of schistosomiasis mansoni (pre-test). 2) Next, an educational intervention was conducted. Pamphlets about schistosomiasis were distributed to the entire school community, who were then invited to a lecture. 3) A post-test was performed using the questionnaire to assess acquired knowledge. 151 elementary school students were interviewed. 2.6% of the pre-test students and 4.3% of the post-test group had already been diagnosed with schistosomiasis. In the pre-test, only 24.5% knew the cause of the disease and 48.3% the transmission sites. In the post-test, 74.3% (OR= 8.9; p-value<0.0001) knew the etiology and 77.1% the possible transmission sites (OR= 3.6; p-value<0.0001). There was also significant improvement in knowledge regarding signs, symptoms and prophylactic measures. Most students were unaware of the risk of reinfection by Schistosoma mansoni after treatment. The educational intervention proved quite effective in increasing information on schistosomiasis. These results reinforce the importance of health education as an auxiliary tool in the control of schistosomiasis.\u0000KEY WORDS: Schistosomiasis mansoni; health education; schoolchildren; neglected tropical diseases; Brazil.","PeriodicalId":36789,"journal":{"name":"Journal of Tropical Pathology","volume":"26 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79448410","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Vanessa Nunes dos Santos Silva, A. C. Da Silva Santos, Valéria Rêgo Alves Pereira, Maria Carolina Accioly Brelaz de Castro
Leishmaniasis is a neglected disease that affects millions of people around the world, mainly socially vulnerable populations and is considered a serious public health problem. Caused by several species of the flagellated protozoa of the Leishmania genus, it is transmitted to man through female sand fly bites. The disease can present the cutaneous, mucocutaneous and visceral clinical forms, varying according to the parasite species and depending on host immune response. Depending on its evolution, the disease may pose serious risks to the afflicted individual’s health. In general, treatment for Leishmaniasis is with pentavalent antimonials, in use for approximately 70 years. However, the existing treatment for Leishmaniasis presents drawbacks such as high toxicity, several side effects, cases of resistance, highlighting the need for new efficient therapeutic approaches. Given all the problems that involve the current treatment of leishmaniasis, it is of paramount importance to seek and screen new molecules that have leishmanicidal activity, meet the safety criteria, while presenting low toxicity, low cost, easy administration and that cure efficiently. This review presents some considerations on the leishmaniasis situation, its treatment and the current panorama for the development of new therapies.KEY WORDS: Leishmania spp.; therapeutics; drug development; immune response.
{"title":"Considerations about leishmaniasis and the current scenario for the development of new treatments","authors":"Vanessa Nunes dos Santos Silva, A. C. Da Silva Santos, Valéria Rêgo Alves Pereira, Maria Carolina Accioly Brelaz de Castro","doi":"10.5216/rpt.v50i4.69817","DOIUrl":"https://doi.org/10.5216/rpt.v50i4.69817","url":null,"abstract":"Leishmaniasis is a neglected disease that affects millions of people around the world, mainly socially vulnerable populations and is considered a serious public health problem. Caused by several species of the flagellated protozoa of the Leishmania genus, it is transmitted to man through female sand fly bites. The disease can present the cutaneous, mucocutaneous and visceral clinical forms, varying according to the parasite species and depending on host immune response. Depending on its evolution, the disease may pose serious risks to the afflicted individual’s health. In general, treatment for Leishmaniasis is with pentavalent antimonials, in use for approximately 70 years. However, the existing treatment for Leishmaniasis presents drawbacks such as high toxicity, several side effects, cases of resistance, highlighting the need for new efficient therapeutic approaches. Given all the problems that involve the current treatment of leishmaniasis, it is of paramount importance to seek and screen new molecules that have leishmanicidal activity, meet the safety criteria, while presenting low toxicity, low cost, easy administration and that cure efficiently. This review presents some considerations on the leishmaniasis situation, its treatment and the current panorama for the development of new therapies.KEY WORDS: Leishmania spp.; therapeutics; drug development; immune response.","PeriodicalId":36789,"journal":{"name":"Journal of Tropical Pathology","volume":"64 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80332013","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kamilla Ferreira Pereira, Verônica Ferreira Batista, Juliana Maria Trindade Bezerra, Thaisa Helena Fonseca Medeiros
This study analyzed the progression of COVID-19 in the State of Espírito Santo, identifying the areas where the disease spread furthest. Temporal and spatial analysis were performed based on confirmed cases of the disease reported in the eSUS/VS System - State Health Department, from March 2020 to February 2021. The highest incidence was noted in July (ranging from 146.1 to 2,099.5 cases per 100,000 inhabitants in the municipalities of Espírito Santo State), with the majority being females, people aged 20 to 39 years and residents in cities in the metropolitan region. A positive and complete high association (p < 0.05) was identified in all months, with clusters containing a greater number of municipalities in April, May and June 2020 in the Central region of the state. The results of the present study indicated a continuous spread of COVID-19 since its introduction, especially in the cities in the Central region of the State of Espírito Santo. These findings present an important aid for decision making regarding the most effective strategies to control the disease. Furthermore, individual and collective protection measures against the transmission of the SARS-CoV-2 must be encouraged. KEY WORDS: COVID-19; SARS-CoV-2; pandemic; spatial analysis; epidemiology; Espirito Santo.
{"title":"Spatial dynamics of COVID-19 cases in a state in the southeast region of Brazil","authors":"Kamilla Ferreira Pereira, Verônica Ferreira Batista, Juliana Maria Trindade Bezerra, Thaisa Helena Fonseca Medeiros","doi":"10.5216/rpt.v50i4.70028","DOIUrl":"https://doi.org/10.5216/rpt.v50i4.70028","url":null,"abstract":"This study analyzed the progression of COVID-19 in the State of Espírito Santo, identifying the areas where the disease spread furthest. Temporal and spatial analysis were performed based on confirmed cases of the disease reported in the eSUS/VS System - State Health Department, from March 2020 to February 2021. The highest incidence was noted in July (ranging from 146.1 to 2,099.5 cases per 100,000 inhabitants in the municipalities of Espírito Santo State), with the majority being females, people aged 20 to 39 years and residents in cities in the metropolitan region. A positive and complete high association (p < 0.05) was identified in all months, with clusters containing a greater number of municipalities in April, May and June 2020 in the Central region of the state. The results of the present study indicated a continuous spread of COVID-19 since its introduction, especially in the cities in the Central region of the State of Espírito Santo. These findings present an important aid for decision making regarding the most effective strategies to control the disease. Furthermore, individual and collective protection measures against the transmission of the SARS-CoV-2 must be encouraged.\u0000KEY WORDS: COVID-19; SARS-CoV-2; pandemic; spatial analysis; epidemiology; Espirito Santo.","PeriodicalId":36789,"journal":{"name":"Journal of Tropical Pathology","volume":"25 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84061954","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Adriana Oliveira Guilarde, Ricardo Vieira Teles Filho, Daniella Da Mata Padilha, Aderrone Vieira Mendes, Kely Tiemi Matsunaga, A. Kipnis, Ariana Rocha Romão Godoi
Yokenella regensburgei belongs to the family Enterobacteriaceae and is an opportunistic agent rarely associated with infections in humans. We report a case of osteoarticular knee infection caused by Y. regensburgei in a patient under treatment for rheumatoid arthritis, using corticosteroids, with complication in primary total arthroplasty of the knee. Y. regensburgei was identified using the VITEK2 system. Antimicrobial susceptibility testing was performed using the disk-diffusion method, according to the guidelines from the Clinical and Laboratory Standards Institute. The patient presented favorable clinical evolution after the second debridement, with complete removal of the prosthesis and antibiotic therapy with sulfamethoxazole/trimethoprim. This is the first case of Y. regensburgei infection described d in Brazil. KEY WORDS: Yokenella regensburgei; osteoarticular; infection; sulfamethoxazole; trimethoprim; prosthesis.
{"title":"YOKENELLA REGENSBURGEI osteoarticular infection: a case report","authors":"Adriana Oliveira Guilarde, Ricardo Vieira Teles Filho, Daniella Da Mata Padilha, Aderrone Vieira Mendes, Kely Tiemi Matsunaga, A. Kipnis, Ariana Rocha Romão Godoi","doi":"10.5216/rpt.v50i4.69205","DOIUrl":"https://doi.org/10.5216/rpt.v50i4.69205","url":null,"abstract":"Yokenella regensburgei belongs to the family Enterobacteriaceae and is an opportunistic agent rarely associated with infections in humans. We report a case of osteoarticular knee infection caused by Y. regensburgei in a patient under treatment for rheumatoid arthritis, using corticosteroids, with complication in primary total arthroplasty of the knee. Y. regensburgei was identified using the VITEK2 system. Antimicrobial susceptibility testing was performed using the disk-diffusion method, according to the guidelines from the Clinical and Laboratory Standards Institute. The patient presented favorable clinical evolution after the second debridement, with complete removal of the prosthesis and antibiotic therapy with sulfamethoxazole/trimethoprim. This is the first case of Y. regensburgei infection described d in Brazil.\u0000KEY WORDS: Yokenella regensburgei; osteoarticular; infection; sulfamethoxazole; trimethoprim; prosthesis.","PeriodicalId":36789,"journal":{"name":"Journal of Tropical Pathology","volume":"69 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83874514","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ana Caroliny Faria Alves, Silvana De Lima Vieira dos Santos, Alexsandra Gomes Resende de Souza da Silva, Júlio César Coelho do Nascimento, Hélio Galdino Júnior, Katiane Martins Mendonça, S. Bisinoto Alves, H. Carneiro Cunha Neves
Given the potential for morbidity and mortality of ventilator-associated pneumonia (VAP), the profile of these infections in adult intensive care units was evaluated in the city of Goiânia. Data were collected from a secondary base in the Department of Prevention and Control of Infection in Health Services, of the Municipal Health Department of Goiânia, from 2014 to 2016, in private (82.7%), public (17.2%), and philanthropic (6.0%) health care services. The rate of use of mechanical ventilation did not change significantly over the three years (32.6%). However, there was a decrease in the mean of VAP incidence density, and in 2016 there was a reduction of 7% in the 90th percentile. These reductions highlight the benefit of the implementation and adherence to bundles by the multidisciplinary team. KEY WORDS: Pneumonia; ventilator-associated; ventilators; mechanical; disease notification.
{"title":"Temporal trends of ventilatorassociated pneumonia in adult intensive care units in the municipality of Goiânia, Goiás, Brazil","authors":"Ana Caroliny Faria Alves, Silvana De Lima Vieira dos Santos, Alexsandra Gomes Resende de Souza da Silva, Júlio César Coelho do Nascimento, Hélio Galdino Júnior, Katiane Martins Mendonça, S. Bisinoto Alves, H. Carneiro Cunha Neves","doi":"10.5216/rpt.v50i4.69511","DOIUrl":"https://doi.org/10.5216/rpt.v50i4.69511","url":null,"abstract":"Given the potential for morbidity and mortality of ventilator-associated pneumonia (VAP), the profile of these infections in adult intensive care units was evaluated in the city of Goiânia. Data were collected from a secondary base in the Department of Prevention and Control of Infection in Health Services, of the Municipal Health Department of Goiânia, from 2014 to 2016, in private (82.7%), public (17.2%), and philanthropic (6.0%) health care services. The rate of use of mechanical ventilation did not change significantly over the three years (32.6%). However, there was a decrease in the mean of VAP incidence density, and in 2016 there was a reduction of 7% in the 90th percentile. These reductions highlight the benefit of the implementation and adherence to bundles by the multidisciplinary team.\u0000KEY WORDS: Pneumonia; ventilator-associated; ventilators; mechanical; disease notification.","PeriodicalId":36789,"journal":{"name":"Journal of Tropical Pathology","volume":"11 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88688767","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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