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Multi-scale hybrid and agent-based modeling of cell differentiation 多尺度混合和基于agent的细胞分化模型
Q3 Mathematics Pub Date : 2023-01-01 DOI: 10.23939/mmc2023.03.617
M. Benmir, K. Bellaj, S. Boujena, V. Volpert
In this work we propose a hybrid model of cell population dynamics, where cells are considered as discrete elements whose dynamics depending on the intracellular and extracellular regulation. The model takes into account different cell types which include undifferentiated cells and two types of differentiated cells. We use a simulation algorithm based on the dynamical systems approach on the one hand, and the multi-agent approach on the other hand. Both approaches have been implemented using NetLogo and Python. We discuss cell choice between two types of differentiated cells and analyze the coexistence of cell lineages.
在这项工作中,我们提出了一个细胞种群动力学的混合模型,其中细胞被认为是离散的元素,其动力学取决于细胞内和细胞外的调节。该模型考虑了不同的细胞类型,包括未分化细胞和两种分化细胞。我们采用了一种基于动态系统方法和多智能体方法的仿真算法。这两种方法都是使用NetLogo和Python实现的。我们讨论了两种类型分化细胞之间的细胞选择,并分析了细胞系的共存。
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引用次数: 0
Stability analysis and Hopf bifurcation of a delayed prey–predator model with Hattaf–Yousfi functional response and Allee effect 一类具有hataf - youfi功能响应和Allee效应的延迟捕食-捕食模型的稳定性分析和Hopf分岔
Q3 Mathematics Pub Date : 2023-01-01 DOI: 10.23939/mmc2023.03.668
S. Bouziane, E. Lotfi, K. Hattaf, N. Yousfi
The Allee effect is an important phenomena in the context of ecology characterized by a correlation between population density and the mean individual fitness of a population. In this work, we examine the influences of Allee effect on the dynamics of a delayed prey–predator model with Hattaf–Yousfi functional response. We first prove that the proposed model with Allee effect is mathematically and ecologically well-posed. Moreover, we study the stability of equilibriums and discuss the local existence of Hopf bifurcation.
Allee效应是种群密度与种群平均个体适应度之间存在相关性的重要生态学现象。在这项工作中,我们研究了Allee效应对具有hataf - youfi功能反应的延迟捕食-捕食模型动力学的影响。我们首先证明了具有Allee效应的模型在数学上和生态学上是适定的。此外,我们研究了平衡点的稳定性,并讨论了Hopf分岔的局部存在性。
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引用次数: 1
Modeling and mathematical analysis of drug addiction with the study of the effect of psychological and biological treatment 药物成瘾的建模和数学分析与心理和生物治疗效果的研究
Q3 Mathematics Pub Date : 2023-01-01 DOI: 10.23939/mmc2023.03.935
E. M. Moumine, O. Balatif, M. Rachik
In this article, we propose a discrete mathematical model which describes the propagation of the drug phenomenon in a human population. The population is unscrewed in five compartments: "S" People likely to become drug addicts, "M" Moderate drug addicts, "H" Heavy drug addicts, "T" People receiving drug addiction treatment, "R" The recovered people who have completely abstained from drug addiction. Our goal is to find a better strategy to reduce the number of heavy addicts and to maximize the number of people receiving full treatment. The tools of optimal control theory were used in this study, in particular the Pontryagin maximum principle.
在本文中,我们提出了一个离散数学模型来描述药物现象在人群中的传播。人口被分成五个部分:“S”可能成为瘾君子的人,“M”中度瘾君子,“H”重度瘾君子,“T”正在接受戒毒治疗的人,“R”已经完全戒除毒瘾的康复者。我们的目标是找到一种更好的策略来减少重度成瘾者的数量,并最大限度地增加接受全面治疗的人数。本研究使用了最优控制理论的工具,特别是庞特里亚金极大值原理。
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引用次数: 1
Homogenization of subwavelength free stratified edge of viscoelastic media including finite size effect 含有限尺寸效应的粘弹性介质亚波长自由分层边缘均匀化
Q3 Mathematics Pub Date : 2023-01-01 DOI: 10.23939/mmc2023.01.010
R. Belemou, A. Sbitti, J.-J. Marigo, A. Tsouli
This paper proposes the homogenization for a stratified viscoelastic media with free edge. We consider the effect of two-dimensional periodically stratified slab over a semi-infinite viscoelastic ground on the propagation of shear waves hitting the interface. Within the harmonic regime, the second order homogenization and matched-asymptotic expansions method is employed to derive an equivalent anisotropic slab associated with effective boundary and jump conditions for the displacement and the normal stress across an interface. The reflection coefficients and the displacement fields are obtained in closed forms and their validity is inspected by comparison with direct numerics in the case of layers associated with Neumann boundary conditions.
提出了具有自由边的层状粘弹性介质的均匀化问题。研究了半无限粘弹性地基上的二维周期性层合板对接触界面的剪切波传播的影响。在谐波区域内,采用二阶均匀化和匹配渐近展开方法,导出了具有有效边界和跳跃条件的等效各向异性板。以封闭形式得到了反射系数和位移场,并通过与直接数值的比较检验了它们在Neumann边界条件下的有效性。
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引用次数: 1
Fractional derivative model for tumor cells and immune system competition 肿瘤细胞与免疫系统竞争的分数阶导数模型
Q3 Mathematics Pub Date : 2023-01-01 DOI: 10.23939/mmc2023.02.288
M. Elkaf, K. Allali
Modeling a dynamics of complex biologic disease such as cancer still present a complex dealing. So, we try in our case to study it by considering the system of normal cells, tumor cells and immune response as mathematical variables structured in fractional-order derivatives equations which express the dynamics of cancer's evolution under immunity of the body. We will analyze the stability of the formulated system at different equilibrium points. Numerical simulations are carried out to get more helpful and specific outcome about the variations of the cancer's dynamics.
对复杂生物疾病(如癌症)的动力学建模仍然是一个复杂的过程。因此,在我们的案例中,我们试图通过将正常细胞,肿瘤细胞和免疫反应系统视为分数阶导数方程中的数学变量来研究它,这些方程表达了机体免疫作用下癌症进化的动力学。我们将分析系统在不同平衡点的稳定性。数值模拟是为了得到更有帮助和更具体的关于肿瘤动力学变化的结果。
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引用次数: 6
Numerical modeling of heat and mass transfer processes in a capillary-porous body during contact drying 接触干燥过程中毛细管多孔体传热传质过程的数值模拟
Q3 Mathematics Pub Date : 2023-01-01 DOI: 10.23939/mmc2023.02.387
B. Gayvas, B. Markovych, A. Dmytruk, M. Havran, V. Dmytruk
The problem of conductive (contact) drying of a capillary-porous body in a steam-air (gas) environment by heat transfer to the material during its contact with the heated surfaces of the material is considered. A system of significantly nonlinear differential equations of heat and mass transfer to describe such a process is obtained. To solve the formulated problem of heat and mass transfer (without taking into account deformability), the method of solving nonlinear boundary value problems is applied in the form of an iterative process, at each step of which a linear boundary value problem is solved. The results of the application of the method are verified based on the popular numerical scheme used. They agree well. A numerical experiment is conducted for materials of three types of porosity. The results are presented graphically and tabularly. The regularities of contact drying of capillary-porous materials in a steam-air environment are deduced.
考虑了毛细管多孔体在蒸汽-空气(气体)环境中通过与材料受热表面接触时的热传递而导电(接触)干燥的问题。得到了描述这一过程的显著非线性传热传质微分方程组。为了求解公式化的传热传质问题(不考虑可变形性),以迭代过程的形式应用求解非线性边值问题的方法,每一步求解一个线性边值问题。基于常用的数值格式,验证了该方法的应用结果。他们意见很一致。对三种孔隙率的材料进行了数值试验。结果以图表形式呈现。推导了毛细管多孔材料在蒸汽-空气环境下接触干燥的规律。
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引用次数: 1
A drip irrigation prediction system in a greenhouse based on long short-term memory and connected objects 基于长短期记忆和连接对象的温室滴灌预测系统
Q3 Mathematics Pub Date : 2023-01-01 DOI: 10.23939/mmc2023.02.524
M. Ghazouani, M. Azzouazi, M. A. Lamhour
Smart greenhouses use Internet of Things (IoT) technology to monitor and control various factors that affect plant growth, such as soil humidity, indoor humidity, soil temperature, rain sensor, illumination, and indoor temperature. Sensors and actuators connected to an IoT network can collect data on these factors and use it to automate processes such as watering, heating, and ventilation. This can help optimize growing conditions and improve crop yield. To enable their vegetative growth and development, plants need the right amount of water at the right time. The objective of this work is to strictly control the different factors that affect the growth of greenhouse crops. Therefore, we need a non-linear prediction model to perform greenhouse crop irrigation prediction. During operation, the system receives the input commands via sensors and then predicts the next watering run. The irrigation is predicted using GRU, LSTM, and BLSTM and a comparison was made between the results of the three techniques, and the technique with the best result was selected.
智能温室利用物联网(IoT)技术监测和控制影响植物生长的各种因素,如土壤湿度、室内湿度、土壤温度、雨水传感器、照明和室内温度。连接到物联网网络的传感器和执行器可以收集这些因素的数据,并使用它来自动化浇水、加热和通风等过程。这有助于优化生长条件,提高作物产量。为了使植物的营养生长和发育,植物需要在适当的时间获得适量的水。这项工作的目的是严格控制影响温室作物生长的各种因素。因此,我们需要一个非线性预测模型来进行温室作物灌溉预测。在操作过程中,系统通过传感器接收输入命令,然后预测下一次浇水。利用GRU、LSTM和BLSTM对灌溉进行预测,并对三种技术的结果进行比较,选择效果最好的技术。
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引用次数: 0
Dynamic von Karman equations with viscous damping 具有粘性阻尼的动态von Karman方程
Q3 Mathematics Pub Date : 2023-01-01 DOI: 10.23939/mmc2023.03.816
B. El-Aqqad, J. Oudaani, A. El Mouatasim
In this paper we are interested to the dynamic von Karman equations coupled with viscous damping and without rotational forces, (α=0) [Chueshov I., Lasiecka I. (2010)], this problem describes the buckling and flexible phenomenon of small nonlinear vibration of vertical displacement to the elastic plates. Our fundamental goal is to establish the existence and the uniqueness to the weak solution for the so-called global energy, under assumption F0∈H3+ϵ(ω). Finally for illustrate our theoretical results we use the finite difference method.
在本文中,我们感兴趣的是耦合粘性阻尼和无旋转力(α=0)的动态von Karman方程[Chueshov I., Lasiecka I.(2010)],该问题描述了垂直位移的小非线性振动对弹性板的屈曲和柔性现象。我们的基本目标是在假设F0∈H3+ ε (ω)下,建立所谓全局能量弱解的存在性和唯一性。最后,为了说明我们的理论结果,我们使用了有限差分法。
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引用次数: 0
European option pricing under model involving slow growth volatility with jump 慢增长波动率跳跃模型下的欧式期权定价
Q3 Mathematics Pub Date : 2023-01-01 DOI: 10.23939/mmc2023.03.889
E. Aatif, A. El Mouatasim
In this paper, we suggest a new model for establishing a numerical study related to a European options pricing problem where assets' prices can be described by a stochastic equation with a discontinuous sample path (Slow Growth Volatility with Jump SGVJ model) which uses a non-standard volatility. A special attention is given to characteristics of the proposed model represented by its non-standard volatility defined by the parameters α and β. The mathematical modeling in the presence of jump shows that one has to resort to a degenerate partial integro-differential equation (PIDE) which the resolution of this one gives a price of the European option as a function of time, price of the underlying asset and the instantaneous volatility. However, in general, an exact or closed solution to this problem is not available. For this reason we approximate it using a finite difference method. At the end of the paper, we present some numerical and comparison results with some classical models known in the literature.
本文提出了一个新的模型,用于建立与欧洲期权定价问题相关的数值研究,其中资产价格可以用一个具有不连续样本路径的随机方程来描述(慢增长波动率与跳跃SGVJ模型),该模型使用非标准波动率。特别注意了模型的特征,即由参数α和β定义的非标准波动率。存在跳变的数学模型表明,必须借助于退化的偏积分-微分方程(PIDE),该方程的解给出欧式期权价格作为时间、标的资产价格和瞬时波动率的函数。然而,一般来说,这个问题的精确或封闭的解决方案是不可用的。由于这个原因,我们用有限差分法近似它。在文章的最后,我们给出了一些数值结果,并与文献中已知的一些经典模型进行了比较。
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引用次数: 1
Mathematical modeling and optimal control strategy for the monkeypox epidemic 猴痘流行的数学建模与最优控制策略
Q3 Mathematics Pub Date : 2023-01-01 DOI: 10.23939/mmc2023.03.944
A. El Mansouri, I. Smouni, B. Khajji, A. Labzai, M. Belam
In this study, we propose a discrete time mathematical model (SEIQR) that describes the dynamics of monkeypox within a human population. The studied population is divided into five compartments: susceptible (S), exposed (E), infected (I), quarantined (Q), and recovered (R). Also, we propose an optimal strategy to fight against the spread of this epidemic. In this sense we use three controls which represent: 1) the awarness of vulnerable people through the media, civil society and education; 2) the quarantine of infected persons at home or, if required, in hospital; 3) encouraging of vaccination of susceptible persons. To characterize these optimal controls, we apply the Pontryagin's maximum principle. The optimality system is solved numerically using Matlab. Therefore, the obtained results confirm the effectiveness of the proposed optimization approach.
在这项研究中,我们提出了一个离散时间数学模型(SEIQR)来描述猴痘在人群中的动态。将研究人群分为易感人群(S)、暴露人群(E)、感染人群(I)、隔离人群(Q)和恢复人群(R)五个区域。同时,我们提出了对抗该流行病传播的最佳策略。在这个意义上,我们使用三种控制方法,它们代表:1)通过媒体、民间社会和教育提高弱势群体的意识;(二)在家隔离,必要时在医院隔离;3)鼓励易感人群接种疫苗。为了描述这些最优控制,我们应用了庞特里亚金极大值原理。利用Matlab对优化系统进行了数值求解。因此,所得结果证实了所提优化方法的有效性。
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引用次数: 0
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Mathematical Modeling and Computing
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