The case report presented by Arabadzhiev et al. [1] aims to show that l-ascorbic acid (3000mg/day, for 10 days) can control persistent severe pain (NRPS grade 8/10) persistent on a mandibular incisor which does not retroceded despite 6 weeks of drug treatment (antibiotic therapy, tramadol, ibuprofen, noramidopyrine), dental treatment (root canal treatment, apicectomie) physical treatment (diode laser) and infiltration of bupivacaine 0.5%. Faced with such a complex clinical status, three-dimensional imaging would have been of great help in the diagnosis. Technetium-99m bone scintigraphy would also have ruled out an infectious bone etiology [2]. The extrapolation of the therapeutic efficacy of ascorbic acid on pain associated with colorectal and gastric cancers, bone metastases, post herpetic neuralgia or labial herpes to pulp necrosis pain still remain controversial. l-ascorbic acid has an anti-inflammatory and antioxidant action and acts on the central nervous system and the patient’s immunity. It would be necessary to know the metabolic profile and the immunological status of the patient as well as her antecedents. It seems risky to systematize ascorbic acid in persistent post-surgical pain without prior dosage, the daily intake being already around 100mg. The contraindications of ascorbic acid (calcium oxalate urolithiasis, phenylketonuria, primary hemochromatosis, G6PD deficiency or thalassemia etc.) must also be evaluated when high doses are proposed. Vitamin C, especially in high doses, is a source of increase in serotonin by hydrolization of triptophan which can, on the contrary, be a source of sensitization to pain as serotonin acts on the serotoninergic receptors 5-HT1A, 5-HT1B, and 5-HT3 which are pro-nociceptive [3]. The pronounced role of serotonin is well identified at the periphery, locally during inflammatory processes, but it is also exerted during nerve damage. Regarding the lack of effectiveness of the diodlaser 810 nm with an intensity of 1.6W and 300 J/session reported by the authors, it is noticable that low-level laser used
{"title":"Does l-ascorbic acid have an analgesic effect?","authors":"Jacques-Christian Beatrix, M. Sorel, A. Alantar","doi":"10.1051/MBCB/2021006","DOIUrl":"https://doi.org/10.1051/MBCB/2021006","url":null,"abstract":"The case report presented by Arabadzhiev et al. [1] aims to show that l-ascorbic acid (3000mg/day, for 10 days) can control persistent severe pain (NRPS grade 8/10) persistent on a mandibular incisor which does not retroceded despite 6 weeks of drug treatment (antibiotic therapy, tramadol, ibuprofen, noramidopyrine), dental treatment (root canal treatment, apicectomie) physical treatment (diode laser) and infiltration of bupivacaine 0.5%. Faced with such a complex clinical status, three-dimensional imaging would have been of great help in the diagnosis. Technetium-99m bone scintigraphy would also have ruled out an infectious bone etiology [2]. The extrapolation of the therapeutic efficacy of ascorbic acid on pain associated with colorectal and gastric cancers, bone metastases, post herpetic neuralgia or labial herpes to pulp necrosis pain still remain controversial. l-ascorbic acid has an anti-inflammatory and antioxidant action and acts on the central nervous system and the patient’s immunity. It would be necessary to know the metabolic profile and the immunological status of the patient as well as her antecedents. It seems risky to systematize ascorbic acid in persistent post-surgical pain without prior dosage, the daily intake being already around 100mg. The contraindications of ascorbic acid (calcium oxalate urolithiasis, phenylketonuria, primary hemochromatosis, G6PD deficiency or thalassemia etc.) must also be evaluated when high doses are proposed. Vitamin C, especially in high doses, is a source of increase in serotonin by hydrolization of triptophan which can, on the contrary, be a source of sensitization to pain as serotonin acts on the serotoninergic receptors 5-HT1A, 5-HT1B, and 5-HT3 which are pro-nociceptive [3]. The pronounced role of serotonin is well identified at the periphery, locally during inflammatory processes, but it is also exerted during nerve damage. Regarding the lack of effectiveness of the diodlaser 810 nm with an intensity of 1.6W and 300 J/session reported by the authors, it is noticable that low-level laser used","PeriodicalId":37322,"journal":{"name":"Journal of Oral Medicine and Oral Surgery","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"57961685","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lombardi Niccolò, Sorrentino Daniela, Bianchi Arianna, Nicali Andrea, M. Laura, Cucurullo Marco, R. Dimitri
Adenomatoid odontogenic tumor (AOT) is a benign, slow-growing lesion and it is considered the fourth most common odontogenic tumor. AOT affects more frequently the young subjects with a predilection for the second and third decades of life. We present here the case of a 36-year-old man affected by large extrafollicular AOT which caused roots resorption of multiple teeth. The lesion involved the entire right maxillary bone and extended into the right maxillary sinus up to the orbital floor and the nasal cavity. Intra-oral surgical excision of the AOT and functional endoscopic sinus surgery led to complete clinical healing in absence of local recurrences.
{"title":"Maxillary extrafollicular adenomatoid odontogenic tumor: root resorption and involvement of the maxillary sinus and nasal cavity","authors":"Lombardi Niccolò, Sorrentino Daniela, Bianchi Arianna, Nicali Andrea, M. Laura, Cucurullo Marco, R. Dimitri","doi":"10.1051/MBCB/2021008","DOIUrl":"https://doi.org/10.1051/MBCB/2021008","url":null,"abstract":"Adenomatoid odontogenic tumor (AOT) is a benign, slow-growing lesion and it is considered the fourth most common odontogenic tumor. AOT affects more frequently the young subjects with a predilection for the second and third decades of life. We present here the case of a 36-year-old man affected by large extrafollicular AOT which caused roots resorption of multiple teeth. The lesion involved the entire right maxillary bone and extended into the right maxillary sinus up to the orbital floor and the nasal cavity. Intra-oral surgical excision of the AOT and functional endoscopic sinus surgery led to complete clinical healing in absence of local recurrences.","PeriodicalId":37322,"journal":{"name":"Journal of Oral Medicine and Oral Surgery","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"57961765","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Introduction: Denosumab is indicated in oncology to reduce tumoral development. However, this medication may cause osteonecrosis of the jaw, especially after dental extractions. Drug holiday has been proposed to decrease the risk of osteonecrosis of the jaw. This survey aimed to assess the management of drug holidays for patients who needed both dental extraction and denosumab. Methods: A questionnaire was sent to a panel of healthcare professionals. Results: Of the 33 practitioners interviewed, 28 undertook or “were used to” dental extractions in patients on denosumab. 25% (7/28) of the practitioners questioned did not stop patients from taking denosumab before dental extraction and 75% (21/28) used a drug holiday. For those who stopped the treatment, 33% (7/21) waited 2 months before performing dental extraction and 38% (8/21) waited 2 months after the dental extraction before reintroducing the molecule; 2 months being the median duration in both cases. In addition, 89% (25/28) of practitioners, modified their surgical procedure for these patients. Conclusion: Despite a small number of responders, it seemed that a drug holiday of at least 2 months is mandatory before performing tooth extraction. The issue of the drug holiday should always be raised with the patient's oncologist.
{"title":"Clinical attitude regarding denosumab drug-holiday for dental extraction in oncologic patients: a national survey","authors":"Claire Lainé, A. Desoutter, A. Chaux","doi":"10.1051/mbcb/2021014","DOIUrl":"https://doi.org/10.1051/mbcb/2021014","url":null,"abstract":"Introduction: Denosumab is indicated in oncology to reduce tumoral development. However, this medication may cause osteonecrosis of the jaw, especially after dental extractions. Drug holiday has been proposed to decrease the risk of osteonecrosis of the jaw. This survey aimed to assess the management of drug holidays for patients who needed both dental extraction and denosumab. Methods: A questionnaire was sent to a panel of healthcare professionals. Results: Of the 33 practitioners interviewed, 28 undertook or “were used to” dental extractions in patients on denosumab. 25% (7/28) of the practitioners questioned did not stop patients from taking denosumab before dental extraction and 75% (21/28) used a drug holiday. For those who stopped the treatment, 33% (7/21) waited 2 months before performing dental extraction and 38% (8/21) waited 2 months after the dental extraction before reintroducing the molecule; 2 months being the median duration in both cases. In addition, 89% (25/28) of practitioners, modified their surgical procedure for these patients. Conclusion: Despite a small number of responders, it seemed that a drug holiday of at least 2 months is mandatory before performing tooth extraction. The issue of the drug holiday should always be raised with the patient's oncologist.","PeriodicalId":37322,"journal":{"name":"Journal of Oral Medicine and Oral Surgery","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"57961924","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Abbas M. Mungia, S. Owibingire, J. Moshy, K. Sohal, William Sianga
Introduction: Hemangiomas arise from the proliferation of endothelial cells surrounding blood-filled cavities. They have a slightly higher female predilection and about 60–70% of them occur in the head and neck region. Various medical and surgical options are available for the treatment of hemangiomas. Aim: To determine the pattern and management outcomes of head and neck hemangiomas in Tanzania. Material and methods: This was a one-year prospective, cross-sectional study that involved all consecutive patients with head and neck hemangiomas treated in Muhimbili National Hospital. A structured questionnaire was used to collect information including age and sex of the patient, chief complaint and, duration, size and site of the lesion. The treatment modalities were surgery and/or intralesional bleomycin injection (IL-Bleo). A standard dose of bleomycin was 0.3 to 0.6 mg/kg per injection not exceeding 15 units per cycle with a maximum of 6 cycles. Frequency distribution and cross-tabulation were performed and association between variables was assessed by the Chi-square test, whereby the p-value was set at p < 0.05. Results: A total of 58 patients were included in the study. The male to female ratio was 1:1.4 and the median age was 6.15 years. Majority (74%) of the patients had infantile hemangioma. The most common presenting complaint of patients/guardians of the patients were facial disfigurement (94.8%), pain (32.8%) and ulceration (22.4%). The most frequently involved sites were the lips (55.2%) followed by the cheeks (37.9%). In patient who were managed surgically, there was a 100% reduction in size of the lesion. Of those who were treated with bleomycin, the percentage reduction in the area of the lesion ranged from 8.33% to 100% with mean of 72.6%. Only 6% of the patient had post IL-Bleo complications. Conclusion: Head and Neck hemangiomas are more common in females and majority are infantile hemangioma. Facial disfigurement is the commonest presenting complication of these lesions, and the lips and the cheeks are mostly affected areas. Intralesional bleomycin is an effective treatment modality which has low complication rates.
{"title":"Pattern and management outcomes of head and neck hemangiomas: a prospective study from Tanzania","authors":"Abbas M. Mungia, S. Owibingire, J. Moshy, K. Sohal, William Sianga","doi":"10.1051/mbcb/2021022","DOIUrl":"https://doi.org/10.1051/mbcb/2021022","url":null,"abstract":"Introduction: Hemangiomas arise from the proliferation of endothelial cells surrounding blood-filled cavities. They have a slightly higher female predilection and about 60–70% of them occur in the head and neck region. Various medical and surgical options are available for the treatment of hemangiomas. Aim: To determine the pattern and management outcomes of head and neck hemangiomas in Tanzania. Material and methods: This was a one-year prospective, cross-sectional study that involved all consecutive patients with head and neck hemangiomas treated in Muhimbili National Hospital. A structured questionnaire was used to collect information including age and sex of the patient, chief complaint and, duration, size and site of the lesion. The treatment modalities were surgery and/or intralesional bleomycin injection (IL-Bleo). A standard dose of bleomycin was 0.3 to 0.6 mg/kg per injection not exceeding 15 units per cycle with a maximum of 6 cycles. Frequency distribution and cross-tabulation were performed and association between variables was assessed by the Chi-square test, whereby the p-value was set at p < 0.05. Results: A total of 58 patients were included in the study. The male to female ratio was 1:1.4 and the median age was 6.15 years. Majority (74%) of the patients had infantile hemangioma. The most common presenting complaint of patients/guardians of the patients were facial disfigurement (94.8%), pain (32.8%) and ulceration (22.4%). The most frequently involved sites were the lips (55.2%) followed by the cheeks (37.9%). In patient who were managed surgically, there was a 100% reduction in size of the lesion. Of those who were treated with bleomycin, the percentage reduction in the area of the lesion ranged from 8.33% to 100% with mean of 72.6%. Only 6% of the patient had post IL-Bleo complications. Conclusion: Head and Neck hemangiomas are more common in females and majority are infantile hemangioma. Facial disfigurement is the commonest presenting complication of these lesions, and the lips and the cheeks are mostly affected areas. Intralesional bleomycin is an effective treatment modality which has low complication rates.","PeriodicalId":37322,"journal":{"name":"Journal of Oral Medicine and Oral Surgery","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"57962265","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
P. Kouamé, M. Aye, D. Amantchi, Vazoumana Kouyaté, Sylvie Koboh N'guessan Atsé, Traoré Zié, Oheueu S. Saint Honoré, Jeannette A. Adouko
Maxillary osteitis is a bone tissue disease or condition with a dentoalveolar origin. This condition remains a public health concern in most developing countries, particularly in the Ivory Coast. Without appropriate management, it can alter the patient's overall health owing to aesthetic, functional, and psychological complications. This study aimed to provide a better understanding of odontogenic maxillary osteitis to consequently improve its diagnosis and medical care. Three major etiologies of maxillary osteitis have been reported: infectious, traumatic, and physicochemical causes. According to the literature, osteitis is grouped into two clinical forms, namely circumscribed osteitis and diffuse osteitis. Their diagnosis is based on a rigorous clinical examination as well as radiographic, histological, and bacteriological examinations. At the Cocody University Hospital's Odontostomatological Consultation and Treatment Center (CCTOS), patients with the late stages of the condition present with significant, disabling, and unsightly osteocutaneous-mucous lesions. Treatment of this osteitis is preventive, curative, and restorative. Odontogenic maxillary osteitis is encountered frequently and typically at a late stage at the Cocody University Hospital's CCTOS. To limit aesthetic and functional damage, raising awareness among African people about oral hygiene and the need for regular consultations should be encouraged.
{"title":"The prevalence of odontogenic maxillary osteitis at the Cocody University Hospital's Odontostomatological Consultation and Treatment Center (CCTOS), Abidjan (Ivory Coast): clinical and therapeutic aspects","authors":"P. Kouamé, M. Aye, D. Amantchi, Vazoumana Kouyaté, Sylvie Koboh N'guessan Atsé, Traoré Zié, Oheueu S. Saint Honoré, Jeannette A. Adouko","doi":"10.1051/mbcb/2021027","DOIUrl":"https://doi.org/10.1051/mbcb/2021027","url":null,"abstract":"Maxillary osteitis is a bone tissue disease or condition with a dentoalveolar origin. This condition remains a public health concern in most developing countries, particularly in the Ivory Coast. Without appropriate management, it can alter the patient's overall health owing to aesthetic, functional, and psychological complications. This study aimed to provide a better understanding of odontogenic maxillary osteitis to consequently improve its diagnosis and medical care. Three major etiologies of maxillary osteitis have been reported: infectious, traumatic, and physicochemical causes. According to the literature, osteitis is grouped into two clinical forms, namely circumscribed osteitis and diffuse osteitis. Their diagnosis is based on a rigorous clinical examination as well as radiographic, histological, and bacteriological examinations. At the Cocody University Hospital's Odontostomatological Consultation and Treatment Center (CCTOS), patients with the late stages of the condition present with significant, disabling, and unsightly osteocutaneous-mucous lesions. Treatment of this osteitis is preventive, curative, and restorative. Odontogenic maxillary osteitis is encountered frequently and typically at a late stage at the Cocody University Hospital's CCTOS. To limit aesthetic and functional damage, raising awareness among African people about oral hygiene and the need for regular consultations should be encouraged.","PeriodicalId":37322,"journal":{"name":"Journal of Oral Medicine and Oral Surgery","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"57962390","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dear Editor, In addition to the current residency curricular reform (“Réforme du 3 cycle” or R3C in short) and another highly understandable medical resident strike (pertaining to their unacceptable weekly working hours), 2021 is also the 10-year anniversary of our “new” surgical specialty, cursorily named “Oral Surgery”, an appropriate time to reflect on the strengths and pitfalls of the curriculum implemented so far. In an editorial from 2016, whilst discussing the current situation of Oral Medicine practice in France and lack of formal specialty (as opposed to numerous other countries who have Oral Medicine specialists), Pr Jean-Christophe FRICAIN aptly raised an important question:Will Oral Surgery save Oral Medicine? [2]. Nevertheless, I believe that the converse question could also be raised: Will Oral Medicine save Oral Surgery? Considering the aforementioned lack of specialty training in Oral Medicine, both in medical and dental practices, Oral Surgery is by necessity a “medico-surgical” specialty (to use the French expression), similarly to otorhinolaryngology for instance. Nevertheless, as previously suggested, I strongly believe Oral Surgery to be a “medico-surgical” specialty not (only) by necessity but by nature, Oral Medicine and Oral Surgery being but two sides of the same coin [3]. In a period when more and more residents are turning towards lifestyle surgical specialties (i.e. better pay, better work/life balance, fewer hours) [4], including private practice-performed Oral Surgery, this issue is far from trivial. As academics, if we do not sufficiently promote the unfortunately less considered and less remunerated Oral Medicine part of our specialty, the consequences for the patients will be dire and our specialty will clearly not flourish as hoped. From an historical perspective, it is interesting to note that the arbitrary separation between Medicine and Surgery, still prevailing today to some extent, has been the subject of much
{"title":"Oral Medicine and Oral Surgery: two sides of the same coin","authors":"N. Moreau","doi":"10.1051/mbcb/2021030","DOIUrl":"https://doi.org/10.1051/mbcb/2021030","url":null,"abstract":"Dear Editor, In addition to the current residency curricular reform (“Réforme du 3 cycle” or R3C in short) and another highly understandable medical resident strike (pertaining to their unacceptable weekly working hours), 2021 is also the 10-year anniversary of our “new” surgical specialty, cursorily named “Oral Surgery”, an appropriate time to reflect on the strengths and pitfalls of the curriculum implemented so far. In an editorial from 2016, whilst discussing the current situation of Oral Medicine practice in France and lack of formal specialty (as opposed to numerous other countries who have Oral Medicine specialists), Pr Jean-Christophe FRICAIN aptly raised an important question:Will Oral Surgery save Oral Medicine? [2]. Nevertheless, I believe that the converse question could also be raised: Will Oral Medicine save Oral Surgery? Considering the aforementioned lack of specialty training in Oral Medicine, both in medical and dental practices, Oral Surgery is by necessity a “medico-surgical” specialty (to use the French expression), similarly to otorhinolaryngology for instance. Nevertheless, as previously suggested, I strongly believe Oral Surgery to be a “medico-surgical” specialty not (only) by necessity but by nature, Oral Medicine and Oral Surgery being but two sides of the same coin [3]. In a period when more and more residents are turning towards lifestyle surgical specialties (i.e. better pay, better work/life balance, fewer hours) [4], including private practice-performed Oral Surgery, this issue is far from trivial. As academics, if we do not sufficiently promote the unfortunately less considered and less remunerated Oral Medicine part of our specialty, the consequences for the patients will be dire and our specialty will clearly not flourish as hoped. From an historical perspective, it is interesting to note that the arbitrary separation between Medicine and Surgery, still prevailing today to some extent, has been the subject of much","PeriodicalId":37322,"journal":{"name":"Journal of Oral Medicine and Oral Surgery","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"57962463","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Introduction: Post-transplant lymphoproliferations (PTL) are a severe complication of solid organ transplants. Their locations can be extra-nodal. Observation: The diagnosis and management of a non-Hodgkin's plasmablastic lymphoma of mandibular localization affecting a 66-year-old kidney transplanted patient are reported here. Comment: The main risk factors for non-Hodgkin lymphoma are immunosuppression and infection with Epstein-Barr virus. Clinical and radiographic examinations, which are not specific, must be supplemented by a histological examination. Treatment which is not consensual will most often consist of a reduction in immunosuppression coupled with chemotherapy. Conclusion: Despite a constant evolution in the incidence and clinical picture of post-transplant lymphomas, the role of the dentist remains essential in the early detection of lesions.
{"title":"Diagnosis of a plasmoblastic lymphoma of the mandible after renal transplantation: a case report","authors":"Inès Legeard, Marc-Antoine Chevrollier, G. Bader","doi":"10.1051/mbcb/2021036","DOIUrl":"https://doi.org/10.1051/mbcb/2021036","url":null,"abstract":"Introduction: Post-transplant lymphoproliferations (PTL) are a severe complication of solid organ transplants. Their locations can be extra-nodal. Observation: The diagnosis and management of a non-Hodgkin's plasmablastic lymphoma of mandibular localization affecting a 66-year-old kidney transplanted patient are reported here. Comment: The main risk factors for non-Hodgkin lymphoma are immunosuppression and infection with Epstein-Barr virus. Clinical and radiographic examinations, which are not specific, must be supplemented by a histological examination. Treatment which is not consensual will most often consist of a reduction in immunosuppression coupled with chemotherapy. Conclusion: Despite a constant evolution in the incidence and clinical picture of post-transplant lymphomas, the role of the dentist remains essential in the early detection of lesions.","PeriodicalId":37322,"journal":{"name":"Journal of Oral Medicine and Oral Surgery","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"57962627","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Introduction: Kaposi's sarcoma (KS) is a malignant mucocutaneous neoplasm caused by human herpesvirus 8 (HHV-8). Four types of KS exist and, in each of them, the patient could develop skin and visceral lesions. Surgical excision, radiotherapy, intralesional chemotherapy and systemic chemotherapy are widely accepted as treatment options. Observation: The aim of this paper is to present diode laser as minimally invasive procedure in management of oral KS. We report here a case of multiple oral lesions of acquired immunodeficiency syndrome (AIDS)-associated KS, which has been solely treated with diode laser. Discussion: There is no bibliography on local treatment of oral KS with diode laser and this clinical case appears to be the first regarding this technique. Conclusion: This conservative approach, in association with highly active antiretroviral therapy (HAART), is safe and effective, shows fewer side effects than chemotherapy, radiotherapy and surgical excision and may be evaluated as potential treatment for oral KS.
{"title":"Diode laser as local treatment for oral Kaposi's sarcoma in HIV young patient: a case report","authors":"N. Lombardi, E. Varoni, L. Moneghini, G. Lodi","doi":"10.1051/MBCB/2021005","DOIUrl":"https://doi.org/10.1051/MBCB/2021005","url":null,"abstract":"Introduction: Kaposi's sarcoma (KS) is a malignant mucocutaneous neoplasm caused by human herpesvirus 8 (HHV-8). Four types of KS exist and, in each of them, the patient could develop skin and visceral lesions. Surgical excision, radiotherapy, intralesional chemotherapy and systemic chemotherapy are widely accepted as treatment options. Observation: The aim of this paper is to present diode laser as minimally invasive procedure in management of oral KS. We report here a case of multiple oral lesions of acquired immunodeficiency syndrome (AIDS)-associated KS, which has been solely treated with diode laser. Discussion: There is no bibliography on local treatment of oral KS with diode laser and this clinical case appears to be the first regarding this technique. Conclusion: This conservative approach, in association with highly active antiretroviral therapy (HAART), is safe and effective, shows fewer side effects than chemotherapy, radiotherapy and surgical excision and may be evaluated as potential treatment for oral KS.","PeriodicalId":37322,"journal":{"name":"Journal of Oral Medicine and Oral Surgery","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"57961674","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Today, oral surgeons routinely meet bone complications in patients receiving anti-resorptive treatments. Bisphosphonates and Denosumab are both osteoclast-targeted anti-resorptive therapy which may cause osteonecrosis of the jaw, also known as Medication-Related Osteonecrosis of Jaws (MRONJ)
{"title":"Medication-related osteonecrosis of jaws revisited through the bone inherited disorders: what do we know?","authors":"M. Fénelon, J. Fricain","doi":"10.1051/MBCB/2021015","DOIUrl":"https://doi.org/10.1051/MBCB/2021015","url":null,"abstract":"Today, oral surgeons routinely meet bone complications in patients receiving anti-resorptive treatments. Bisphosphonates and Denosumab are both osteoclast-targeted anti-resorptive therapy which may cause osteonecrosis of the jaw, also known as Medication-Related Osteonecrosis of Jaws (MRONJ)","PeriodicalId":37322,"journal":{"name":"Journal of Oral Medicine and Oral Surgery","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"57961940","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Introduction: Condyle fracture can be treated surgically (ORIF) or conservatively (CTR). When treated by CTR, the fracture might not heal in a morphologically ideal shape. The severity of the deformity and its effects on the functional outcome is not known. This study would investigate the anatomical outcome of CTR and its effect on the functional outcome. Methods: Using a cross-sectional study design, we enrolled patients identified from our trauma census that meets the pre-determined inclusion criteria. Patient underwent assessment which involves clinical and radiographic evaluation. Clinical examination was done by using Helkimo Index. Radiographic evaluation by using cone beam computed tomography (CBCT) scan were traced and digitized, and the position and morphology of the fractured mandibular condyle was measured and compared with those of the contralateral non-fractured condyle in the axial, coronal and sagittal planes. Radiographic data was then compared with data from clinical examination. Results: 25 patients with unilateral condyle fracture and met the inclusion criteria were identified. Eight patients were successfully recalled and included in the study. Assessment was done on average of 40 months post-treatment. Clinical assessment with Helkimo Index showed that 63% had at least mild temporomandibular symptoms or dysfunction. CBCT examinations revealed that most patients had morphologically deformed healed condyle. No pattern can be seen in the magnitude of deformity with functional outcome. Conclusions: Following CTR, condyle fracture would heal in a morphologically deformed shape. Satisfactory functional outcome is still attainable despite this. The magnitude of the deformity does not appear to influence the functional outcome.
{"title":"Does magnitude of deformity correlate with functional outcome following closed reduction in unilateral condylar fracture?","authors":"S. Nabil, A. Nazimi","doi":"10.1051/MBCB/2020065","DOIUrl":"https://doi.org/10.1051/MBCB/2020065","url":null,"abstract":"Introduction: Condyle fracture can be treated surgically (ORIF) or conservatively (CTR). When treated by CTR, the fracture might not heal in a morphologically ideal shape. The severity of the deformity and its effects on the functional outcome is not known. This study would investigate the anatomical outcome of CTR and its effect on the functional outcome. Methods: Using a cross-sectional study design, we enrolled patients identified from our trauma census that meets the pre-determined inclusion criteria. Patient underwent assessment which involves clinical and radiographic evaluation. Clinical examination was done by using Helkimo Index. Radiographic evaluation by using cone beam computed tomography (CBCT) scan were traced and digitized, and the position and morphology of the fractured mandibular condyle was measured and compared with those of the contralateral non-fractured condyle in the axial, coronal and sagittal planes. Radiographic data was then compared with data from clinical examination. Results: 25 patients with unilateral condyle fracture and met the inclusion criteria were identified. Eight patients were successfully recalled and included in the study. Assessment was done on average of 40 months post-treatment. Clinical assessment with Helkimo Index showed that 63% had at least mild temporomandibular symptoms or dysfunction. CBCT examinations revealed that most patients had morphologically deformed healed condyle. No pattern can be seen in the magnitude of deformity with functional outcome. Conclusions: Following CTR, condyle fracture would heal in a morphologically deformed shape. Satisfactory functional outcome is still attainable despite this. The magnitude of the deformity does not appear to influence the functional outcome.","PeriodicalId":37322,"journal":{"name":"Journal of Oral Medicine and Oral Surgery","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"57962091","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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