Mario Morcel, P. Keribin, L. Quenel, H. Bertin, A. Néel, P. Lesclous
Introduction: Langerhans cell histiocytosis (LCH) is an abnormal clonal proliferation of Langerhans cells secondary to immune process, mutation of oncogene or genetic predispositions. It preferentially affects bone, lung and skin. The incidence is 2–6 cases per million per year. Prognosis is variable and depends on number and location of lesions, and impact of the initial treatment. Oral lesions may be the first sign of LCH as illustrated by the present case. Observation: A 24-year-old male consulted first for severe gingival inflammation, teeth mobilities and alveolar bone loss with a suspicion of LCH. A pulmonary involvement was secondarily revealed by tomodensitometry. Histological examination, from gingival biopsy, confirmed the diagnostic of LCH, showing cells positive for the anti-CD1A antibody. The patient was managed by oral surgery and chemotherapy approaches. Alveolar bone loss significantly reduced. But 2 years and a half after the diagnosis, a recurrence was noted and managed by surgical approach. After a three-year follow-up, no recurrence was noted. Conclusion: Oral lesions can be inaugural manifestations of LCH. The dentist has an essential role in the early detection of these lesions.
{"title":"Diagnosis, treatment and recurrence of a mandibular Langerhans cell histiocytosis: a three-year follow-up case report","authors":"Mario Morcel, P. Keribin, L. Quenel, H. Bertin, A. Néel, P. Lesclous","doi":"10.1051/mbcb/2022027","DOIUrl":"https://doi.org/10.1051/mbcb/2022027","url":null,"abstract":"Introduction: Langerhans cell histiocytosis (LCH) is an abnormal clonal proliferation of Langerhans cells secondary to immune process, mutation of oncogene or genetic predispositions. It preferentially affects bone, lung and skin. The incidence is 2–6 cases per million per year. Prognosis is variable and depends on number and location of lesions, and impact of the initial treatment. Oral lesions may be the first sign of LCH as illustrated by the present case. Observation: A 24-year-old male consulted first for severe gingival inflammation, teeth mobilities and alveolar bone loss with a suspicion of LCH. A pulmonary involvement was secondarily revealed by tomodensitometry. Histological examination, from gingival biopsy, confirmed the diagnostic of LCH, showing cells positive for the anti-CD1A antibody. The patient was managed by oral surgery and chemotherapy approaches. Alveolar bone loss significantly reduced. But 2 years and a half after the diagnosis, a recurrence was noted and managed by surgical approach. After a three-year follow-up, no recurrence was noted. Conclusion: Oral lesions can be inaugural manifestations of LCH. The dentist has an essential role in the early detection of these lesions.","PeriodicalId":37322,"journal":{"name":"Journal of Oral Medicine and Oral Surgery","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"57963004","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
I. Thakrar, B. Carey, R. Cook, Luis Monteiro, M. Diniz-Freitas, Niccolò Lombardi, J. Fricain, V. Brailo, J. Limeres, E. Varoni, M. Fénelon, Danica Vidović Juras, Luis Silva, M. Escudier, G. Lodi, Silvian Catros, Ivana Škrinjar, R. Ariyaratnam, Božana Lončar Brzak, A. Andabak Rogulj, R. Albuquerque
An e-learning education resource on the topic of oral potentially malignant disorders Ishita Thakrar, Barbara Carey, Richard Cook, Luis Monteiro, Márcio Diniz-Freitas, Niccolò Lombardi, Jean-Cristophe Fricain, Vlaho Brailo, Jacobo Limeres, Elena Varoni, Mathilde Fenelon, Danica Vidović Juras, Luis Silva, Michael Escudier, Giovanni Lodi, Silvian Catros, Ivana Skrinjar, Raj Ariyaratnam, Bozana Loncar Brzak, Ana Andabak Rogulj, Rui Albuquerque 1 Oral Medicine Department, Guy’s & St Thomas’ NHS Foundation Trust, London, UK 2 Faculty of Dentistry, Oral & Craniofacial Sciences, King’s College London, UK 3 Medicine and Oral Surgery Department, University Institute of Health Sciences (IUCS), UNIPRO, CESPU, Gandra, Portugal 4 Special Care Dentistry Unit, School of Medicine and Dentistry, University Santiago de Compostela, Spain 5 Dipartimento di Scienze Biomediche, Chirurgiche e odontoiatriche, Università degli Studi di Milano, Italy 6 Oral Surgery Department, University of Bordeaux, France 7 Oral Medicine Department, School of Dental Medicine, University of Zagreb, Croatia 8 University of Manchester, UK
关于口腔潜在恶性疾病主题的在线学习教育资源Ishita Thakrar, Barbara Carey, Richard Cook, Luis Monteiro, Márcio Diniz-Freitas, Niccolò Lombardi, jean - christophe Fricain, Vlaho Brailo, Jacobo Limeres, Elena Varoni, Mathilde Fenelon, Danica vidoviki Juras, Luis Silva, Michael Escudier, Giovanni Lodi, Silvian Catros, Ivana Skrinjar, Raj Ariyaratnam, Bozana Loncar Brzak, Ana Andabak Rogulj, Rui Albuquerque 1口腔医学部门英国伦敦盖伊和圣托马斯NHS基金会信托基金2英国伦敦国王学院口腔和颅面科学牙科学院3葡萄牙Gandra CESPU UNIPRO健康科学大学(IUCS)医学和口腔外科4西班牙圣地亚哥孔波斯特拉大学医学和牙科学院特殊护理牙科科5意大利米兰大学生物医学科学和口腔医学专业6口腔外科7克罗地亚萨格勒布大学口腔医学院口腔医学系8英国曼彻斯特大学
{"title":"An e-learning education resource on the topic of oral potentially malignant disorders","authors":"I. Thakrar, B. Carey, R. Cook, Luis Monteiro, M. Diniz-Freitas, Niccolò Lombardi, J. Fricain, V. Brailo, J. Limeres, E. Varoni, M. Fénelon, Danica Vidović Juras, Luis Silva, M. Escudier, G. Lodi, Silvian Catros, Ivana Škrinjar, R. Ariyaratnam, Božana Lončar Brzak, A. Andabak Rogulj, R. Albuquerque","doi":"10.1051/mbcb/2022033","DOIUrl":"https://doi.org/10.1051/mbcb/2022033","url":null,"abstract":"An e-learning education resource on the topic of oral potentially malignant disorders Ishita Thakrar, Barbara Carey, Richard Cook, Luis Monteiro, Márcio Diniz-Freitas, Niccolò Lombardi, Jean-Cristophe Fricain, Vlaho Brailo, Jacobo Limeres, Elena Varoni, Mathilde Fenelon, Danica Vidović Juras, Luis Silva, Michael Escudier, Giovanni Lodi, Silvian Catros, Ivana Skrinjar, Raj Ariyaratnam, Bozana Loncar Brzak, Ana Andabak Rogulj, Rui Albuquerque 1 Oral Medicine Department, Guy’s & St Thomas’ NHS Foundation Trust, London, UK 2 Faculty of Dentistry, Oral & Craniofacial Sciences, King’s College London, UK 3 Medicine and Oral Surgery Department, University Institute of Health Sciences (IUCS), UNIPRO, CESPU, Gandra, Portugal 4 Special Care Dentistry Unit, School of Medicine and Dentistry, University Santiago de Compostela, Spain 5 Dipartimento di Scienze Biomediche, Chirurgiche e odontoiatriche, Università degli Studi di Milano, Italy 6 Oral Surgery Department, University of Bordeaux, France 7 Oral Medicine Department, School of Dental Medicine, University of Zagreb, Croatia 8 University of Manchester, UK","PeriodicalId":37322,"journal":{"name":"Journal of Oral Medicine and Oral Surgery","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"57962710","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Introduction: Masseter muscle enlargement accompanied by hypertrophy of Mandibular angle can significantly affect the appearance and quality of life. The treatment methods can be varied, and, in the present study, osteotomy of Mandibular angle and treatment of Masseter muscle with Botulinum toxin was carried out. Observation: In this case study, a 19-year-old female patient was admitted with inadequate mouth opening for three years. Clinical examination and Cone-Beam Computed Tomography scan revealed bilateral well-developed Masseter muscles and hypertrophy of mandibular angle on both sides. Osteotomy of mandibular angle was performed. Additionally, 25 units of Botulinum toxin were administered. This improved the aesthetic appearance and increased the mouth opening from 21 mm to 38 mm in one year after surgery. Conclusion: Oral and maxillofacial surgeons should consider Masticatory muscle tendon-aponeurosis hyperplasia as a differential diagnosis when the patient's chief complaint is inadequate mouth-opening with a square mandible. Osteotomy of mandibular angle in conjunction with, Botulinum toxin is efficient in cases of Masseter muscle hypertrophy and an enlargement of the Mandibular angle.
{"title":"Masticatory muscle tendon-aponeurosis hyperplasia: clinical presentation and management","authors":"Ahmed Al Qattan, Ahmed Al Hashmi, S. Al Rashdi","doi":"10.1051/mbcb/2022022","DOIUrl":"https://doi.org/10.1051/mbcb/2022022","url":null,"abstract":"Introduction: Masseter muscle enlargement accompanied by hypertrophy of Mandibular angle can significantly affect the appearance and quality of life. The treatment methods can be varied, and, in the present study, osteotomy of Mandibular angle and treatment of Masseter muscle with Botulinum toxin was carried out. Observation: In this case study, a 19-year-old female patient was admitted with inadequate mouth opening for three years. Clinical examination and Cone-Beam Computed Tomography scan revealed bilateral well-developed Masseter muscles and hypertrophy of mandibular angle on both sides. Osteotomy of mandibular angle was performed. Additionally, 25 units of Botulinum toxin were administered. This improved the aesthetic appearance and increased the mouth opening from 21 mm to 38 mm in one year after surgery. Conclusion: Oral and maxillofacial surgeons should consider Masticatory muscle tendon-aponeurosis hyperplasia as a differential diagnosis when the patient's chief complaint is inadequate mouth-opening with a square mandible. Osteotomy of mandibular angle in conjunction with, Botulinum toxin is efficient in cases of Masseter muscle hypertrophy and an enlargement of the Mandibular angle.","PeriodicalId":37322,"journal":{"name":"Journal of Oral Medicine and Oral Surgery","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"57962943","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aim: To assess the prevalence of acute periapical abscesses (PAs) in patients infected with herpes simplex type 1 (HS-1) and herpes zoster (HZ). Materials and methods: Integrated data of hospital patients was used. History of HS-1 and HZ diagnosis was retrieved by searching the appropriate query in the database. All cases were diagnosed for acute PAs by calibrated dentists in a hospital setting for patients admitted to urgent care. Diagnosis was made based on clinical examination and imaging data confirming the diagnosis of acute PAs without sinus tract. The odds ratio (OR) for the prevalence of acute PAs and its association with history of HS-1 and HZ were then calculated. Results: The prevalence of acute PAs in patients with a history HS-1 was 2.43% as compared to 0.59% in the general patient population of the hospital. The OR was 4.12 and the difference in prevalence was statistically significant (p < 0.0001). The prevalence of acute PAs in patients with a history HZ was 2.78% as compared to 0.59% in the general patient population of the hospital. The OR was 4.71 and the difference in prevalence was statistically significant (p < 0.0001). Conclusions: Under the conditions of this study, it appears that the prevalence of acute PAs is significantly higher in patients with a history of HS-1 and HZ infections and may warrant an antiviral therapy in certain resistant periapical abscesses.
{"title":"Acute periapical abscesses in patients with herpes simplex type 1 and herpes zoster","authors":"I. Rotstein, J. Katz","doi":"10.1051/mbcb/2022028","DOIUrl":"https://doi.org/10.1051/mbcb/2022028","url":null,"abstract":"Aim: To assess the prevalence of acute periapical abscesses (PAs) in patients infected with herpes simplex type 1 (HS-1) and herpes zoster (HZ). Materials and methods: Integrated data of hospital patients was used. History of HS-1 and HZ diagnosis was retrieved by searching the appropriate query in the database. All cases were diagnosed for acute PAs by calibrated dentists in a hospital setting for patients admitted to urgent care. Diagnosis was made based on clinical examination and imaging data confirming the diagnosis of acute PAs without sinus tract. The odds ratio (OR) for the prevalence of acute PAs and its association with history of HS-1 and HZ were then calculated. Results: The prevalence of acute PAs in patients with a history HS-1 was 2.43% as compared to 0.59% in the general patient population of the hospital. The OR was 4.12 and the difference in prevalence was statistically significant (p < 0.0001). The prevalence of acute PAs in patients with a history HZ was 2.78% as compared to 0.59% in the general patient population of the hospital. The OR was 4.71 and the difference in prevalence was statistically significant (p < 0.0001). Conclusions: Under the conditions of this study, it appears that the prevalence of acute PAs is significantly higher in patients with a history of HS-1 and HZ infections and may warrant an antiviral therapy in certain resistant periapical abscesses.","PeriodicalId":37322,"journal":{"name":"Journal of Oral Medicine and Oral Surgery","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"57963061","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pauline Dussueil, J. Sergent, A. Veyssière, H. Bénateau
Introduction: Noonan Syndrome is a clinically and genetically heterogeneous syndrome, characterized by marked phenotypic variability. All the clinical manifestations of this syndrome are still not fully known. Observation: We present the case of a 58-year-old woman with a diagnosis of Neurofibromatosis-Noonan syndrome with SOS2 mutation, observed by her general practitioner for a recurrent left upper lip abscess despite drainage and antibiotic therapy. The anatomo-pathological result of the sample was in favor of an infected xanthoma. Discussion: The most common oral manifestation of Noonan syndrome includes malocclusion, dental anomalies and radiologic jaw lesions. Xanthomas of the lip have never been reported in this syndrome. Conclusion: Oral xanthomas could be one of the many oral clinical manifestations of Noonan Syndrome. However, more research is needed to understand clinical consequences of mutations in identified genes.
{"title":"Recurrent labial xanthoma infection in a patient with Neurofibromatosis-Noonan syndrome: case report and literature review","authors":"Pauline Dussueil, J. Sergent, A. Veyssière, H. Bénateau","doi":"10.1051/mbcb/2022029","DOIUrl":"https://doi.org/10.1051/mbcb/2022029","url":null,"abstract":"Introduction: Noonan Syndrome is a clinically and genetically heterogeneous syndrome, characterized by marked phenotypic variability. All the clinical manifestations of this syndrome are still not fully known. Observation: We present the case of a 58-year-old woman with a diagnosis of Neurofibromatosis-Noonan syndrome with SOS2 mutation, observed by her general practitioner for a recurrent left upper lip abscess despite drainage and antibiotic therapy. The anatomo-pathological result of the sample was in favor of an infected xanthoma. Discussion: The most common oral manifestation of Noonan syndrome includes malocclusion, dental anomalies and radiologic jaw lesions. Xanthomas of the lip have never been reported in this syndrome. Conclusion: Oral xanthomas could be one of the many oral clinical manifestations of Noonan Syndrome. However, more research is needed to understand clinical consequences of mutations in identified genes.","PeriodicalId":37322,"journal":{"name":"Journal of Oral Medicine and Oral Surgery","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"57963077","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
C. Petagna, Laure Bocqueho, Camille Framery, Gwenola Ferrec, Héloïse Herry, L. Miséry, S. Boisramé
Introduction: Oral lichen planus is an autoimmune inflammatory disease. These clinical manifestations can sometimes be confused and cumulated with clinical signs of periodontal disorders. The aim of this work is to illustrate the interest of a periodontal follow-up in the management of oral lichen planus by a clinical case report. Observation: A patient came for a consultation in dermatology for a persistent gingival erythema. The diagnosis of oral lichen planus was made and treatments were successively implemented. After six months of follow-up, an inflammatory gum was still present without showing improvement. A stage 3, grade B periodontitis associated with oral lichen planus was diagnosed and a periodontal treatment was initiated, combined with corticosteroids treatment as mouthwash. Four months after the beginning of this treatment, a marked decrease in gingival erythema was observed. Comments: There is often a close relationship between oral lichen planus and periodontal disease therefore a multidisciplinary approach can be very useful for optimal management.
{"title":"Interest of periodontal maintenance in improving autoimmune diseases: about an oral lichen planus case report","authors":"C. Petagna, Laure Bocqueho, Camille Framery, Gwenola Ferrec, Héloïse Herry, L. Miséry, S. Boisramé","doi":"10.1051/mbcb/2021046","DOIUrl":"https://doi.org/10.1051/mbcb/2021046","url":null,"abstract":"Introduction: Oral lichen planus is an autoimmune inflammatory disease. These clinical manifestations can sometimes be confused and cumulated with clinical signs of periodontal disorders. The aim of this work is to illustrate the interest of a periodontal follow-up in the management of oral lichen planus by a clinical case report. Observation: A patient came for a consultation in dermatology for a persistent gingival erythema. The diagnosis of oral lichen planus was made and treatments were successively implemented. After six months of follow-up, an inflammatory gum was still present without showing improvement. A stage 3, grade B periodontitis associated with oral lichen planus was diagnosed and a periodontal treatment was initiated, combined with corticosteroids treatment as mouthwash. Four months after the beginning of this treatment, a marked decrease in gingival erythema was observed. Comments: There is often a close relationship between oral lichen planus and periodontal disease therefore a multidisciplinary approach can be very useful for optimal management.","PeriodicalId":37322,"journal":{"name":"Journal of Oral Medicine and Oral Surgery","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"57962203","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nadia Sultana Shuborna, Lee Kian Khoo, Bishwa Prakash Bhattarai, Teeranut Chaiyasamut, S. Kiattavorncharoen, V. Pairuchvej, N. Wongsirichat
Background: Hyaluronic acid (HA) has the potential to promote wound healing. Pain and swelling with trismus are common sequalae post wisdom teeth removal. This study aims to investigate the effectiveness of intra-socket HA solution to reduce these uncomfortable post-operative events. Materials and methods: 30 patients underwent bilateral extractions of mandibular wisdom teeth for this study. Intra-socket application of 0.7 ml 20 mg/2 ml HA solution (Hyalgun) with Gel foam as a scaffold in study site versus Gel foam only on control site was conducted via a split mouth study design. Data collection of five facial reference points for swelling and maximum mouth opening was recorded during the pre-operative period and post-operative 2nd and 7th day. The VAS pain score at post-op 1st, 2nd and 3rd day and the number of analgesics for the 7-day post-operative duration were evaluated. Results: The HA group demonstrated statistically significant less swelling, trismus and analgesia consumption on the 2 and 7 days after surgery. VAS scores on day 1, 2 and 3 after surgery (P = 0.05) were significantly less in the HA group compared to the control group. Conclusion: The application of intra-socket HA has a positive effect for reducing postoperative pain and swelling with trismus after the lower third molar intervention (LTMI).
背景:透明质酸(HA)具有促进伤口愈合的潜力。牙关疼痛和肿胀是拔除智齿后常见的后遗症。本研究旨在探讨窝内HA解决方案在减少这些术后不适事件方面的有效性。材料与方法:30例患者行双侧下颌智齿拔除术。通过裂口研究设计，将0.7 ml 20 mg/2 ml HA溶液(Hyalgun)与凝胶泡沫作为支架应用于研究部位，而仅在对照部位使用凝胶泡沫。记录术前、术后第2天、第7天面部肿胀和最大开口5个参考点的数据采集。评估两组患者术后第1、2、3天VAS疼痛评分及术后7天镇痛药使用次数。结果:HA组术后2、7天肿胀、牙关紧闭、镇痛消耗均有统计学意义。HA组术后第1、2、3天VAS评分均低于对照组(P = 0.05)。结论:窝内HA的应用对减轻下第三磨牙介入治疗(LTMI)术后牙关疼痛和肿胀有积极作用。
{"title":"Intra-socket application of Hyaluronic acid reduces pain and swelling following wisdom teeth removal","authors":"Nadia Sultana Shuborna, Lee Kian Khoo, Bishwa Prakash Bhattarai, Teeranut Chaiyasamut, S. Kiattavorncharoen, V. Pairuchvej, N. Wongsirichat","doi":"10.1051/mbcb/2021038","DOIUrl":"https://doi.org/10.1051/mbcb/2021038","url":null,"abstract":"Background: Hyaluronic acid (HA) has the potential to promote wound healing. Pain and swelling with trismus are common sequalae post wisdom teeth removal. This study aims to investigate the effectiveness of intra-socket HA solution to reduce these uncomfortable post-operative events. Materials and methods: 30 patients underwent bilateral extractions of mandibular wisdom teeth for this study. Intra-socket application of 0.7 ml 20 mg/2 ml HA solution (Hyalgun) with Gel foam as a scaffold in study site versus Gel foam only on control site was conducted via a split mouth study design. Data collection of five facial reference points for swelling and maximum mouth opening was recorded during the pre-operative period and post-operative 2nd and 7th day. The VAS pain score at post-op 1st, 2nd and 3rd day and the number of analgesics for the 7-day post-operative duration were evaluated. Results: The HA group demonstrated statistically significant less swelling, trismus and analgesia consumption on the 2 and 7 days after surgery. VAS scores on day 1, 2 and 3 after surgery (P = 0.05) were significantly less in the HA group compared to the control group. Conclusion: The application of intra-socket HA has a positive effect for reducing postoperative pain and swelling with trismus after the lower third molar intervention (LTMI).","PeriodicalId":37322,"journal":{"name":"Journal of Oral Medicine and Oral Surgery","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"57962635","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Raghavendra Vamsi Anegundi, Santhosh B. Shenoy, S. Kaukab, A. Talwar
Clot formation is the first step of the healing process, and clinical procedures always find ways to stabilize this clot better. Platelets play a significant role in clot formation, and Platelet Concentrates (Pc) are an abundant reservoir of platelets. This article aims to review the in vitro research and systematic reviews on PCs that are currently available. Broadly, PCs mainly include Platelet-rich plasma and platelet-rich fibrin. PCs are an excellent source for growth factors such as PDGF-AA, TGF β1, VEGF, EGF, and IGF. Numerous systematic reviews and meta-analyses have analyzed the clinical application of PCs in various periodontal procedures. In alveolar ridge preservation, PCs are known to reduce postoperative pain, edema, trismus, and inflammation. PRF had shown significant improvement in achieving root coverage and recession depth reduction. PCs exhibited a positive influence on CAL gain when used as an adjunct to OFD in treating infra-bony defects. Pcs have a positive effect on bone maturation in the short term. Besides, PCs can be used in regenerative endodontics, treatment of medication-related osteoradionecrosis of Jaw (MRONJ), and accelerating tooth movement. In conclusion, PCs positively affect soft tissue healing, while their role in hard tissue healing is still unclear.
{"title":"Platelet concentrates in periodontics: review of in vivo studies and systematic reviews","authors":"Raghavendra Vamsi Anegundi, Santhosh B. Shenoy, S. Kaukab, A. Talwar","doi":"10.1051/mbcb/2022025","DOIUrl":"https://doi.org/10.1051/mbcb/2022025","url":null,"abstract":"Clot formation is the first step of the healing process, and clinical procedures always find ways to stabilize this clot better. Platelets play a significant role in clot formation, and Platelet Concentrates (Pc) are an abundant reservoir of platelets. This article aims to review the in vitro research and systematic reviews on PCs that are currently available. Broadly, PCs mainly include Platelet-rich plasma and platelet-rich fibrin. PCs are an excellent source for growth factors such as PDGF-AA, TGF β1, VEGF, EGF, and IGF. Numerous systematic reviews and meta-analyses have analyzed the clinical application of PCs in various periodontal procedures. In alveolar ridge preservation, PCs are known to reduce postoperative pain, edema, trismus, and inflammation. PRF had shown significant improvement in achieving root coverage and recession depth reduction. PCs exhibited a positive influence on CAL gain when used as an adjunct to OFD in treating infra-bony defects. Pcs have a positive effect on bone maturation in the short term. Besides, PCs can be used in regenerative endodontics, treatment of medication-related osteoradionecrosis of Jaw (MRONJ), and accelerating tooth movement. In conclusion, PCs positively affect soft tissue healing, while their role in hard tissue healing is still unclear.","PeriodicalId":37322,"journal":{"name":"Journal of Oral Medicine and Oral Surgery","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"57962978","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Y. Kini, Charu Girotra, M. Padhye, G. Tomar, Madhur Kankaria, S. Nebhnani, Aastha Maini, Sagar Meswani
Purpose: This study aims to derive a series of biometric measurements using cone-beam computed tomography (CBCT) from a cross sectional group of population to help the surgeon accurately locate the mandibular foramen and the mental foramen during mandibular osteotomies. Methods: CBCT images of 800 subjects were evaluated. Various measurements were noted and compared between the two sides of the mandible in and between the sexes. Result: Statistically significant values were noted between the right and left sides of Line X to Point A in female subjects, Line Z & Line B only in male subjects and Line X’ in both male and female subjects. However, Line Y was found to be significant when comparing both sides in both males and females and also on correlation between the genders. Conclusion: Although the identification of the mandibular lingula and anatomical landmarks is an important step during mandibular osteotomies, the position of one side, however, cannot be blindly extrapolated to the contra lateral side. Also, pre operative CBCT is a useful tool to derive measurements which when transferred clinically during the surgery gives an accurate and safe approach for localisation of lingula, thus reducing the incidence of post operative neurologic morbidities.
{"title":"Cross sectional analysis of mandibular anthropometric points using CBCT to derive biometric measurements for a safer approach to mandible osteotomies","authors":"Y. Kini, Charu Girotra, M. Padhye, G. Tomar, Madhur Kankaria, S. Nebhnani, Aastha Maini, Sagar Meswani","doi":"10.1051/mbcb/2021047","DOIUrl":"https://doi.org/10.1051/mbcb/2021047","url":null,"abstract":"Purpose: This study aims to derive a series of biometric measurements using cone-beam computed tomography (CBCT) from a cross sectional group of population to help the surgeon accurately locate the mandibular foramen and the mental foramen during mandibular osteotomies. Methods: CBCT images of 800 subjects were evaluated. Various measurements were noted and compared between the two sides of the mandible in and between the sexes. Result: Statistically significant values were noted between the right and left sides of Line X to Point A in female subjects, Line Z & Line B only in male subjects and Line X’ in both male and female subjects. However, Line Y was found to be significant when comparing both sides in both males and females and also on correlation between the genders. Conclusion: Although the identification of the mandibular lingula and anatomical landmarks is an important step during mandibular osteotomies, the position of one side, however, cannot be blindly extrapolated to the contra lateral side. Also, pre operative CBCT is a useful tool to derive measurements which when transferred clinically during the surgery gives an accurate and safe approach for localisation of lingula, thus reducing the incidence of post operative neurologic morbidities.","PeriodicalId":37322,"journal":{"name":"Journal of Oral Medicine and Oral Surgery","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"57962222","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Oral malignant melanoma − an uncommon sinister entity","authors":"Harsha Popli, Ambika Gupta","doi":"10.1051/mbcb/2022003","DOIUrl":"https://doi.org/10.1051/mbcb/2022003","url":null,"abstract":"","PeriodicalId":37322,"journal":{"name":"Journal of Oral Medicine and Oral Surgery","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"57962478","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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