Florian Kappes, Samy Kerrad, Christelle Grémeau-Richard, L. Devoize
Introduction: Burning Mouth Syndrome (BMS) is defined by a burning sensation or intraoral dysesthesia without obvious causal lesion. Despite the development of research, diagnostic aids for this syndrome are non-existent and treatments are partially ineffective. Some studies have shown changes in salivary composition, viscosity or flow in patients with BMS. The evaluation of the salivary biochemical characteristics of patients with BMS could then help to better understand the pathogenesis of this disease. The objective of this meta-analysis is to perform a qualitative and quantitative synthesis of the literature concerning the salivary biomarkers present in patients with BMS in comparison to healthy subjects. Materials and methods: The PubMed, Web of Science and Cochrane databases were searched to identify articles corresponding to the defined inclusion criteria. Review Manager 5.4.1 software was used to perform the quantitative analysis. Results: The quantitative analysis included 15 articles and found a significant increase in salivary concentrations of cortisol and immunoglobulin A (IgA) with a standardized mean difference SMD = 0.53 and a 95% confidence interval CI [0.33 to 0.74] and SMD = 0.32 to 95% CI [0.10 to 0.55] respectively. For calcium and copper, the analysis found no significant difference in patients with BMS with SMD = 0.06 at 95% CI [–0.19 to 0.32] and SMD = -0.19 at 95% CI [–0.44 to 0.06]. Finally, for magnesium, the analysis found a probable decrease with SMD = -0.29 at 95% CI [–0.52 to -0.06]. Four other biomarkers (potassium, alpha amylase, zinc and total protein) showed too high levels of heterogeneity (I² > 44%) to be able to interpret the results with confidence. Discussion: This strong heterogeneity can be explained by different saliva sampling methods or biomarker measurement techniques that are not strictly identical between the studies. In addition, some saliva samples may have undergone blood contamination which may bias the results. Conclusion: This meta-analysis nevertheless confirms all the interest of focusing on salivary biomarkers in BMS patients; the measurement of cortisol and/or salivary IgA could be a line of research for the establishment of a standardized biological assessment. Nevertheless, the number of available studies being low and of variable methodological quality with a limited number of patients, additional studies are necessary to give a firm and definitive conclusion.
{"title":"Salivary biomarkers and burning mouth syndrome: a systematic review and meta-analysis of the literature","authors":"Florian Kappes, Samy Kerrad, Christelle Grémeau-Richard, L. Devoize","doi":"10.1051/mbcb/2023024","DOIUrl":"https://doi.org/10.1051/mbcb/2023024","url":null,"abstract":"Introduction: Burning Mouth Syndrome (BMS) is defined by a burning sensation or intraoral dysesthesia without obvious causal lesion. Despite the development of research, diagnostic aids for this syndrome are non-existent and treatments are partially ineffective. Some studies have shown changes in salivary composition, viscosity or flow in patients with BMS. The evaluation of the salivary biochemical characteristics of patients with BMS could then help to better understand the pathogenesis of this disease. The objective of this meta-analysis is to perform a qualitative and quantitative synthesis of the literature concerning the salivary biomarkers present in patients with BMS in comparison to healthy subjects. Materials and methods: The PubMed, Web of Science and Cochrane databases were searched to identify articles corresponding to the defined inclusion criteria. Review Manager 5.4.1 software was used to perform the quantitative analysis. Results: The quantitative analysis included 15 articles and found a significant increase in salivary concentrations of cortisol and immunoglobulin A (IgA) with a standardized mean difference SMD = 0.53 and a 95% confidence interval CI [0.33 to 0.74] and SMD = 0.32 to 95% CI [0.10 to 0.55] respectively. For calcium and copper, the analysis found no significant difference in patients with BMS with SMD = 0.06 at 95% CI [–0.19 to 0.32] and SMD = -0.19 at 95% CI [–0.44 to 0.06]. Finally, for magnesium, the analysis found a probable decrease with SMD = -0.29 at 95% CI [–0.52 to -0.06]. Four other biomarkers (potassium, alpha amylase, zinc and total protein) showed too high levels of heterogeneity (I² > 44%) to be able to interpret the results with confidence. Discussion: This strong heterogeneity can be explained by different saliva sampling methods or biomarker measurement techniques that are not strictly identical between the studies. In addition, some saliva samples may have undergone blood contamination which may bias the results. Conclusion: This meta-analysis nevertheless confirms all the interest of focusing on salivary biomarkers in BMS patients; the measurement of cortisol and/or salivary IgA could be a line of research for the establishment of a standardized biological assessment. Nevertheless, the number of available studies being low and of variable methodological quality with a limited number of patients, additional studies are necessary to give a firm and definitive conclusion.","PeriodicalId":37322,"journal":{"name":"Journal of Oral Medicine and Oral Surgery","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"57963347","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Oral surgery and maxillofacial surgery: the logic of a single discipline","authors":"Joël Ferri","doi":"10.1051/mbcb/2023030","DOIUrl":"https://doi.org/10.1051/mbcb/2023030","url":null,"abstract":"","PeriodicalId":37322,"journal":{"name":"Journal of Oral Medicine and Oral Surgery","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"57963395","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Preena Shah, Qingmei Feng, Barbara Carey, Marcio Diniz-Freitas, Jacobo Limeres, Luis Monteiro, Luis Silva, Jean-Cristophe Fricain, Sylvain Catros, Mathilde Fenelon, Niccolò Lombardi, Alberto Pispero, Giovanni Lodi, Vlaho Brailo, Danica Vidovi Juras, José López-López, Rui Albuquerque
Actinic cheilitis is an oral potentially malignant disorder caused by UV radiation leading to damage to epithelial keratinocytes of the lips. It predominantly affects the vermillion border of the lower lip. Due to its association with chronic UV exposure, associated risk factors include geographic areas, outdoor occupations, and skin subtypes. A high proportion of lip squamous cell carcinomas arise from actinic cheilitis lesions, with histological examination usually showing a degree of dysplasia. This paper aims to review the existing literature regarding the clinical picture of actinic cheilitis, its prevalence, differential diagnoses, and consensus on management, for the education of the general dental practitioner in identifying and surveillance of this lesion.
{"title":"Actinic cheilitis: guidance on monitoring and management in primary care","authors":"Preena Shah, Qingmei Feng, Barbara Carey, Marcio Diniz-Freitas, Jacobo Limeres, Luis Monteiro, Luis Silva, Jean-Cristophe Fricain, Sylvain Catros, Mathilde Fenelon, Niccolò Lombardi, Alberto Pispero, Giovanni Lodi, Vlaho Brailo, Danica Vidovi Juras, José López-López, Rui Albuquerque","doi":"10.1051/mbcb/2023029","DOIUrl":"https://doi.org/10.1051/mbcb/2023029","url":null,"abstract":"Actinic cheilitis is an oral potentially malignant disorder caused by UV radiation leading to damage to epithelial keratinocytes of the lips. It predominantly affects the vermillion border of the lower lip. Due to its association with chronic UV exposure, associated risk factors include geographic areas, outdoor occupations, and skin subtypes. A high proportion of lip squamous cell carcinomas arise from actinic cheilitis lesions, with histological examination usually showing a degree of dysplasia. This paper aims to review the existing literature regarding the clinical picture of actinic cheilitis, its prevalence, differential diagnoses, and consensus on management, for the education of the general dental practitioner in identifying and surveillance of this lesion.","PeriodicalId":37322,"journal":{"name":"Journal of Oral Medicine and Oral Surgery","volume":"87 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135495163","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Muhammad Kamil Hassan, Namkabir Singh, K. Selvaraju, W. Ngeow
Introduction: Local anesthesia administration albeit being the most common dental procedure is associated with complications that usually arise as a result of wrongly placed injections into local or distant sites. Here we present a case of an unexpected complication affecting the upper limb after dental anesthesia administration. Observation: A 26-year-old Malay female presented with the left upper extremity paralysis and paraesthesia following the administration of a local anesthesia block to the left inferior alveolar nerve, at a dental teaching center. The onset of the dental nerve block and left upper extremity weakness occurred and eventually subsided. As the provisional diagnosis was either a transient ischaemic attack or stroke, she was immediately referred to the Emergency Department. She was thoroughly assessed and monitored with the neurology team being consulted. Her vital signs remained stable and she showed no neurological deterioration throughout the observation period. She was discharged without further investigations after regaining full strength and sensation of her left upper extremity. The report tries to hypothesize the possible cause of this incident. Conclusion: This case highlights the importance of dentists being alert to possible effects of local anesthesia to regions beyond the head and neck area.
{"title":"A stroke mimicker following inferior alveolar nerve block: a case report","authors":"Muhammad Kamil Hassan, Namkabir Singh, K. Selvaraju, W. Ngeow","doi":"10.1051/mbcb/2023021","DOIUrl":"https://doi.org/10.1051/mbcb/2023021","url":null,"abstract":"Introduction: Local anesthesia administration albeit being the most common dental procedure is associated with complications that usually arise as a result of wrongly placed injections into local or distant sites. Here we present a case of an unexpected complication affecting the upper limb after dental anesthesia administration. Observation: A 26-year-old Malay female presented with the left upper extremity paralysis and paraesthesia following the administration of a local anesthesia block to the left inferior alveolar nerve, at a dental teaching center. The onset of the dental nerve block and left upper extremity weakness occurred and eventually subsided. As the provisional diagnosis was either a transient ischaemic attack or stroke, she was immediately referred to the Emergency Department. She was thoroughly assessed and monitored with the neurology team being consulted. Her vital signs remained stable and she showed no neurological deterioration throughout the observation period. She was discharged without further investigations after regaining full strength and sensation of her left upper extremity. The report tries to hypothesize the possible cause of this incident. Conclusion: This case highlights the importance of dentists being alert to possible effects of local anesthesia to regions beyond the head and neck area.","PeriodicalId":37322,"journal":{"name":"Journal of Oral Medicine and Oral Surgery","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"57963280","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lichen planus (LP) is a chronic autoimmune relapsing mucocutaneous disease that significantly affects the patient's quality of life (QoL) and is associated with several etiological factors. Vulvo-vaginal gingival syndrome (VVGS) is characterized as a clinical triad of gingival, vaginal and vulval LP. In previous literature, it has been described as a distinctive pattern of erosive plurimucosal LP. This condition if progressed can lead to multiple complications such as urethral and vaginal stenosis. This case report highlights the management of VVGS using a multidisciplinary strategy that includes dermatological consultation, oral hygiene maintenance, topical steroid application using custom-made trays and photodynamic therapy.
{"title":"Multi-modal approach in management of vulvo-vaginal gingival syndrome − a rare variant of oral lichen planus","authors":"Shwetha V., Sujatha S., Rakesh N., Pavan T., Pooja Rathore","doi":"10.1051/mbcb/2023028","DOIUrl":"https://doi.org/10.1051/mbcb/2023028","url":null,"abstract":"Lichen planus (LP) is a chronic autoimmune relapsing mucocutaneous disease that significantly affects the patient's quality of life (QoL) and is associated with several etiological factors. Vulvo-vaginal gingival syndrome (VVGS) is characterized as a clinical triad of gingival, vaginal and vulval LP. In previous literature, it has been described as a distinctive pattern of erosive plurimucosal LP. This condition if progressed can lead to multiple complications such as urethral and vaginal stenosis. This case report highlights the management of VVGS using a multidisciplinary strategy that includes dermatological consultation, oral hygiene maintenance, topical steroid application using custom-made trays and photodynamic therapy.","PeriodicalId":37322,"journal":{"name":"Journal of Oral Medicine and Oral Surgery","volume":"4 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135494917","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Fusion of primary maxillary incisors","authors":"Mohamed Faizal Asan, Renita Lorina Castelino","doi":"10.1051/mbcb/2023031","DOIUrl":"https://doi.org/10.1051/mbcb/2023031","url":null,"abstract":"","PeriodicalId":37322,"journal":{"name":"Journal of Oral Medicine and Oral Surgery","volume":"35 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135494929","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: Life-threatening illnesses like necrotizing fasciitis (NF) from dental origin arise suddenly and unexpectedly as a result of the debilitating condition and frequent self-medicating behaviour. This article aims to report the medical and therapeutic characteristics of 15 patients while discussing risk factors, pathogenetic mechanisms and management of this disease. Method: From 2012 up to 2022, a retrospective chart study of patients with odontogenic NF was carried out. Demographic, medical and therapeutic data were collected and analysed, using the Excel program. Results: Fifteen patients were identified with retrievable medical records. There was a male predominance, and the age ranged from 13 to 82 years with a majority over 40 years. Preadmission delay was ≤4 days in 40% of patients with self-medication of non-steroid anti-inflammatory drugs. 53.85% of patients had previous dental treatment without antibiotic coverage. Rheumatoid arthritis was the predominant comorbidity followed by diabetes mellitus and anaemia. Multispace involvement was found in 73.33% of patients. Preoperative computed tomography was performed for 60% of patients. Conclusion: Prompt and efficient treatment is required for NF, a polymicrobial odontogenic infection that is lethal even in healthy people. Self-medication and debilitating condition should be considered. Early diagnosis and therapy may reduce mortality and morbidity.
{"title":"Clinical characteristics and management of odontogenic necrotizing fasciitis: a retrospective study","authors":"Imen Mehri Turki","doi":"10.1051/mbcb/2023027","DOIUrl":"https://doi.org/10.1051/mbcb/2023027","url":null,"abstract":"Background: Life-threatening illnesses like necrotizing fasciitis (NF) from dental origin arise suddenly and unexpectedly as a result of the debilitating condition and frequent self-medicating behaviour. This article aims to report the medical and therapeutic characteristics of 15 patients while discussing risk factors, pathogenetic mechanisms and management of this disease. Method: From 2012 up to 2022, a retrospective chart study of patients with odontogenic NF was carried out. Demographic, medical and therapeutic data were collected and analysed, using the Excel program. Results: Fifteen patients were identified with retrievable medical records. There was a male predominance, and the age ranged from 13 to 82 years with a majority over 40 years. Preadmission delay was ≤4 days in 40% of patients with self-medication of non-steroid anti-inflammatory drugs. 53.85% of patients had previous dental treatment without antibiotic coverage. Rheumatoid arthritis was the predominant comorbidity followed by diabetes mellitus and anaemia. Multispace involvement was found in 73.33% of patients. Preoperative computed tomography was performed for 60% of patients. Conclusion: Prompt and efficient treatment is required for NF, a polymicrobial odontogenic infection that is lethal even in healthy people. Self-medication and debilitating condition should be considered. Early diagnosis and therapy may reduce mortality and morbidity.","PeriodicalId":37322,"journal":{"name":"Journal of Oral Medicine and Oral Surgery","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136079488","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lélia Ménager, M. Ruperto, J. Fricain, S. Catros, M. Fénelon
Objective: This study aimed to assess the influence of mandibular third molar surgical removal on the periodontal status of adjacent second molars and to investigate the potential impact of the flap design. Methods: A systematic review of the literature, registered in PROSPERO, has been carried out from Pubmed and Scopus databases following PRISMA guidelines from January 2010 to January 2022. PICO method was used to select the relevant articles. Studies comparing the periodontal status of the second molar before and after mandibular third molar removal were considered. Results: Twenty-three studies involving 1067 patients were included. The two main parameters studied were periodontal pocket depth and clinical attachment level. The envelope flap and the triangular flap were the most commonly used flap techniques. Periodontal health of adjacent second molar was maintained or improved in most of the included studies. The flap design did not seem to have a significant influence either. Conclusion: Avulsion of impacted third molar in healthy young adults does not impair the periodontal health of adjacent second molars. Further studies, with higher levels of evidence, are needed to confirm these results and to identify possible risk factors (such as age, impaction depth or periodontal disease) responsible for poorer healing.
{"title":"Does surgical removal of mandibular third molar influence the periodontal status of the adjacent second molars? A systematic review","authors":"Lélia Ménager, M. Ruperto, J. Fricain, S. Catros, M. Fénelon","doi":"10.1051/mbcb/2022032","DOIUrl":"https://doi.org/10.1051/mbcb/2022032","url":null,"abstract":"Objective: This study aimed to assess the influence of mandibular third molar surgical removal on the periodontal status of adjacent second molars and to investigate the potential impact of the flap design. Methods: A systematic review of the literature, registered in PROSPERO, has been carried out from Pubmed and Scopus databases following PRISMA guidelines from January 2010 to January 2022. PICO method was used to select the relevant articles. Studies comparing the periodontal status of the second molar before and after mandibular third molar removal were considered. Results: Twenty-three studies involving 1067 patients were included. The two main parameters studied were periodontal pocket depth and clinical attachment level. The envelope flap and the triangular flap were the most commonly used flap techniques. Periodontal health of adjacent second molar was maintained or improved in most of the included studies. The flap design did not seem to have a significant influence either. Conclusion: Avulsion of impacted third molar in healthy young adults does not impair the periodontal health of adjacent second molars. Further studies, with higher levels of evidence, are needed to confirm these results and to identify possible risk factors (such as age, impaction depth or periodontal disease) responsible for poorer healing.","PeriodicalId":37322,"journal":{"name":"Journal of Oral Medicine and Oral Surgery","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"57963157","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dear Editor, We would like to thank you for your interest in our paper [1] and for bringing to our attention such important academic and scientific topics of discussion. In the first place, we want to clarify that at the moment the article was submitted, we did not acknowledge the article by Grimaud et al. “Vertical ramus elongation and mandibular advancement by endobuccal approach: Presentation of a new osteotomy technique” [2], because when we performed our literature search in 2020 using PubMed and Medline databases, the following strategies were used: “osteotomy ramus AND orthognathic surgery AND vertical ramus” and “MeSH Term (((“orthognathic surgery”[MeSH Terms]) AND (condyle, mandibular[MeSH Terms])) AND (osteotomy, sagittal split ramus[MeSH Terms])”, and said the article did not appear within the results. However, we now recognize that the article by Girmaud et al., and the article by T. Loncle “Modified technique used for sagittal splitting of the mandible” [3], present very similar techniques with quite the same clinical goals ad results in the treatment of Class II patients with severe loss of posterior facial height; a slight difference could be the fact that the presented cases for this technique were both done using the Wolfords protocol described in 2015 for inactive condylar resorption in Class II patients [4], that carries a simultaneous bilateral meniscopexy, since the loss of posterior facial height was attributed to the past condylar resorption. In addition, it needs to be stated that any kind of mandibular osteotomy design that included the gonial area in the distal fragment, could bear the same results such as the L-inverted osteotomy, the Epker-modified Wolford osteotomy and the Caldwell-Letterman technique, as you stated [5–7]; only, they face a greater restriction in the amount of mandibular advancement that can be achieved.
{"title":"Reply to “A modified sagittal split osteotomy: description of technique”","authors":"Dario Andrés Bastidas Castillo, Pamela Ramirez Naranjo","doi":"10.1051/mbcb/2023014","DOIUrl":"https://doi.org/10.1051/mbcb/2023014","url":null,"abstract":"Dear Editor, We would like to thank you for your interest in our paper [1] and for bringing to our attention such important academic and scientific topics of discussion. In the first place, we want to clarify that at the moment the article was submitted, we did not acknowledge the article by Grimaud et al. “Vertical ramus elongation and mandibular advancement by endobuccal approach: Presentation of a new osteotomy technique” [2], because when we performed our literature search in 2020 using PubMed and Medline databases, the following strategies were used: “osteotomy ramus AND orthognathic surgery AND vertical ramus” and “MeSH Term (((“orthognathic surgery”[MeSH Terms]) AND (condyle, mandibular[MeSH Terms])) AND (osteotomy, sagittal split ramus[MeSH Terms])”, and said the article did not appear within the results. However, we now recognize that the article by Girmaud et al., and the article by T. Loncle “Modified technique used for sagittal splitting of the mandible” [3], present very similar techniques with quite the same clinical goals ad results in the treatment of Class II patients with severe loss of posterior facial height; a slight difference could be the fact that the presented cases for this technique were both done using the Wolfords protocol described in 2015 for inactive condylar resorption in Class II patients [4], that carries a simultaneous bilateral meniscopexy, since the loss of posterior facial height was attributed to the past condylar resorption. In addition, it needs to be stated that any kind of mandibular osteotomy design that included the gonial area in the distal fragment, could bear the same results such as the L-inverted osteotomy, the Epker-modified Wolford osteotomy and the Caldwell-Letterman technique, as you stated [5–7]; only, they face a greater restriction in the amount of mandibular advancement that can be achieved.","PeriodicalId":37322,"journal":{"name":"Journal of Oral Medicine and Oral Surgery","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"57963179","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Matteo Di Lorenzo, Andrea Torsani, Paolo Tonveronachi, Samuele Baruch, Christian Caldari
Objectives: The aim of this retrospective study was to investigate possible risk factors for early implant failure in screw retained fixed full-arch rehabilitation. Methods: data of 487 patients (2323 implants) treated with full-arch rehabilitation supported by same implants brand were collected for the time period from 2017 to 2020 and examined to evaluate early implants failure rates. The following data were collected for statistical analysis: sex, age, health disorders (diabetes and hypertension) and bad habit (smoke) of the patient, location of the implant (maxilla or mandible, anterior or posterior site), type of implant's healing and bone regeneration procedures. Chi-squared test, bivariate comparison analysis and univariate mixed model analysis were used to estimate the effect of both patient-related and implant related variables on early implant failure as a potential risk factors. Results: 487 patients were included, 218 females (62.3 ± 9.14 of age) and 269 males (62.8 ± 10.11 of age) in 30 private institutions for a total of 2323 implants placed and a total of 526 screw retained fixed full arch rehabilitation. A total of 40 out of 2323 (1.7%) implants failed prematurely within 1 year, 32 in the maxilla 8 in the mandible. Bivariate comparison analysis and univariate mixed model analysis showed that female patient, implant placed in maxilla, age <61 years and submerged healed implants showed a statistically significant higher failure rate among the risk factors considered. Conclusions: Implants placed in the upper jaw and their modality of healing seems to be associated with a higher risk of early implant failure.
{"title":"Risk factors for early implant failure: a retrospective-multicentric study of 2323 implants in screw retained fixed full arch rehabilitation","authors":"Matteo Di Lorenzo, Andrea Torsani, Paolo Tonveronachi, Samuele Baruch, Christian Caldari","doi":"10.1051/mbcb/2023022","DOIUrl":"https://doi.org/10.1051/mbcb/2023022","url":null,"abstract":"Objectives: The aim of this retrospective study was to investigate possible risk factors for early implant failure in screw retained fixed full-arch rehabilitation. Methods: data of 487 patients (2323 implants) treated with full-arch rehabilitation supported by same implants brand were collected for the time period from 2017 to 2020 and examined to evaluate early implants failure rates. The following data were collected for statistical analysis: sex, age, health disorders (diabetes and hypertension) and bad habit (smoke) of the patient, location of the implant (maxilla or mandible, anterior or posterior site), type of implant's healing and bone regeneration procedures. Chi-squared test, bivariate comparison analysis and univariate mixed model analysis were used to estimate the effect of both patient-related and implant related variables on early implant failure as a potential risk factors. Results: 487 patients were included, 218 females (62.3 ± 9.14 of age) and 269 males (62.8 ± 10.11 of age) in 30 private institutions for a total of 2323 implants placed and a total of 526 screw retained fixed full arch rehabilitation. A total of 40 out of 2323 (1.7%) implants failed prematurely within 1 year, 32 in the maxilla 8 in the mandible. Bivariate comparison analysis and univariate mixed model analysis showed that female patient, implant placed in maxilla, age <61 years and submerged healed implants showed a statistically significant higher failure rate among the risk factors considered. Conclusions: Implants placed in the upper jaw and their modality of healing seems to be associated with a higher risk of early implant failure.","PeriodicalId":37322,"journal":{"name":"Journal of Oral Medicine and Oral Surgery","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"57963322","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}