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An Open-Source Browser-Based Nonlinear Model Predictive Controller for Type 1 Diabetes 基于开源浏览器的1型糖尿病非线性模型预测控制器
Q3 Engineering Pub Date : 2025-01-01 DOI: 10.1016/j.ifacol.2025.06.025
Lara Hauser , John Bagterp Jørgensen , Heiko Peuscher
We provide an open-source implementation of the NMPC algorithm for closed-loop insulin therapy presented by Hovorka et. al. in the seminal paper from 2004. An extended Kalman filter is added as observer, since specifics on state estimation have been omitted in the original paper. The controller is now part of the TypeScript-based closed-loop diabetes simulator LT1, which also comprises a library of models describing CGM sensors, infusion pumps, and patient physiology. The controller can thus be extensively tested in various closed-loop configurations. Also, the graphical user interface enables its integration in educational tools.
我们为Hovorka等人在2004年的开创性论文中提出的闭环胰岛素治疗的NMPC算法提供了一个开源实现。由于原论文中省略了状态估计的细节,因此增加了扩展卡尔曼滤波器作为观测器。该控制器现在是基于typescript的闭环糖尿病模拟器LT1的一部分,LT1还包括一个描述CGM传感器、输液泵和患者生理的模型库。因此,控制器可以在各种闭环配置中进行广泛的测试。此外,图形用户界面使其能够集成到教育工具中。
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引用次数: 0
A Deep Deterministic Policy Gradient control algorithm for Automatic Insulin Delivery 胰岛素自动输送的深度确定性策略梯度控制算法
Q3 Engineering Pub Date : 2025-01-01 DOI: 10.1016/j.ifacol.2025.06.003
Giada Lops, Vito Andrea Racanelli, Gioacchino Manfredi, Luca De Cicco, Saverio Mascolo
This study investigates the use of Reinforcement Learning (RL) to optimize insulin infusion in Automated Insulin Delivery (AID) systems. The Deep Deterministic Policy Gradient (DDPG) algorithm is evaluated as a potential control strategy and compared to Model Predictive Control (MPC) and PID controllers using a highly realistic in silico simulation model. Simulations for adult Type 1 Diabetes (T1D) patients demonstrate that the DDPG controller effectively reduces hypo- and hyperglycemic episodes and improves glucose stability.
本研究探讨了在自动胰岛素输送(AID)系统中使用强化学习(RL)来优化胰岛素输注。深度确定性策略梯度(DDPG)算法作为一种潜在的控制策略进行了评估,并使用高度逼真的计算机仿真模型与模型预测控制(MPC)和PID控制器进行了比较。对成人1型糖尿病(T1D)患者的模拟表明,DDPG控制器有效地减少了低血糖和高血糖发作,并改善了血糖稳定性。
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引用次数: 0
Multiple Constrained MPCs for glucose regulation in Type 1 Diabetes1 多约束MPCs对1型糖尿病的血糖调节作用
Q3 Engineering Pub Date : 2025-01-01 DOI: 10.1016/j.ifacol.2025.06.006
Matteo Ragni , Paolo A. Mongini , Lalo Magni , Chiara Toffanin
This study introduces a personalized Model Predictive Control (MPC) strategy for managing type 1 diabetes, specifically addressing intra-day variability in glucose regulation. The proposed method uses a soft-switching mechanism combining multiple MPCs, each optimized for distinct day periods (breakfast, lunch, and dinner). Patient-specific models were identified using an enhanced impulse response technique, featuring a novel clinically-based cost function to better capture circadian dynamics. A switching mechanism ensures smooth transitions between controllers, minimizing disruptions. Performance was evaluated using the FDA-approved UVA/Padova simulator, demonstrating a 20% improvement in model fit and enhanced control performance compared to the state-of-art approach. The strategy consistently prevented hypoglycemia while improving time-in-target metrics.
本研究引入了一种个性化的模型预测控制(MPC)策略来管理1型糖尿病,特别是处理葡萄糖调节的日间变异性。所提出的方法使用结合多个mpc的软开关机制,每个mpc针对不同的一天时间段(早餐,午餐和晚餐)进行优化。使用增强的脉冲响应技术确定了患者特异性模型,该模型具有新颖的基于临床的成本函数,以更好地捕捉昼夜动力学。切换机制确保控制器之间的平稳过渡,最大限度地减少中断。使用fda批准的UVA/Padova模拟器对性能进行评估,与最先进的方法相比,模型拟合改善了20%,控制性能增强。该策略持续预防低血糖,同时改善目标时间指标。
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引用次数: 0
The Lazy Student’s Dream: ChatGPT Passing an Engineering Course on Its Own 懒惰学生的梦想:ChatGPT自己通过工程课程
Q3 Engineering Pub Date : 2025-01-01 DOI: 10.1016/j.ifacol.2025.08.049
Gokul Puthumanaillam, Timothy Bretl, Melkior Ornik
This paper presents a comprehensive investigation into the capability of Large Language Models (LLMs) to successfully complete a semester-long undergraduate control systems course. Through evaluation of 115 course deliverables, we assess LLM performance using ChatGPT under a “minimal effort” protocol that simulates realistic student usage patterns. The investigation employs a rigorous testing methodology across multiple assessment formats, from auto-graded multiple choice questions to complex Python programming tasks and long-form analytical writing. Our analysis provides quantitative insights into AI’s strengths and limitations in handling mathematical formulations, coding challenges, and theoretical concepts in control systems engineering. The LLM achieved a B-grade performance (82.24%), approaching but not exceeding the class average (84.99%), with strongest results in structured assignments and greatest limitations in open-ended projects. The findings inform discussions about course design adaptation in response to AI advancement, moving beyond simple prohibition towards thoughtful integration of these tools in engineering education. Additional materials including syllabus, examination papers, design projects, and example responses can be found at the project website: https://gradegpt.github.io.
本文对大型语言模型(LLMs)成功完成一个学期的本科控制系统课程的能力进行了全面的研究。通过对115门课程成果的评估,我们在模拟现实学生使用模式的“最小努力”协议下使用ChatGPT评估LLM的表现。调查采用了严格的测试方法,涵盖多种评估格式,从自动评分的选择题到复杂的Python编程任务和长篇分析写作。我们的分析提供了人工智能在处理数学公式、编码挑战和控制系统工程理论概念方面的优势和局限性的定量见解。LLM取得了b级成绩(82.24%),接近但不超过班级平均成绩(84.99%),其中结构化作业成绩最好,开放式项目限制最大。研究结果为课程设计适应人工智能进步的讨论提供了信息,不再是简单的禁止,而是将这些工具深思熟虑地整合到工程教育中。其他材料包括教学大纲、试卷、设计项目和示例回答可以在项目网站上找到:https://gradegpt.github.io。
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引用次数: 0
Interdisciplinary Control Research and Curriculum Development in CPSS: A Case Study with 3D Printing and Social Manufacturing CPSS的跨学科控制研究和课程开发:以3D打印和社会制造为例
Q3 Engineering Pub Date : 2025-01-01 DOI: 10.1016/j.ifacol.2025.08.056
Zhen Shen , Hongyu Li , Jing Yang , Xiaojun Wang , Daniel Horti , Martin Ferenc Dömény , Szatmáry Sára , Adina Chotbaeva , Jimei Ma , Zsombor Zrubka , Fei-Yue Wang
This paper presents a novel educational framework that integrates additive manufacturing (3D printing), social manufacturing platforms, large language models (LLMs), iSTREAMS, and iCDIOS to bridge academic learning, industrial practice, and research innovation. The framework adopts a “learning-by-doing” approach, where students engage in project-driven tasks that span 2D-to-3D modeling, material property optimization, and collaborative problem-solving. By leveraging AI tools for design iteration and real-time feedback, students develop competencies in critical thinking, technical execution, and interdisciplinary collaboration. The framework also emphasizes dynamic assessment mechanisms that combine human evaluation with AI-driven analytics to provide personalized feedback and inform curriculum updates. Through this integrated approach, students are equipped with the skills necessary to navigate the complexities of modern Cyber-Physical-Social Systems (CPSS)-driven industries. A case study is provided to demonstrate the framework’s implementation and its potential to foster interdisciplinary control research and curriculum development, highlighting the synergy between iSTREAMS and iCDIOS in enhancing educational outcomes.
本文提出了一个新的教育框架,它集成了增材制造(3D打印)、社交制造平台、大型语言模型(llm)、iSTREAMS和iCDIOS,以架起学术学习、工业实践和研究创新的桥梁。该框架采用“边做边学”的方法,学生参与项目驱动的任务,包括2d到3d建模、材料属性优化和协作解决问题。通过利用人工智能工具进行设计迭代和实时反馈,学生可以培养批判性思维、技术执行和跨学科合作的能力。该框架还强调动态评估机制,将人工评估与人工智能驱动的分析相结合,提供个性化反馈并通知课程更新。通过这种综合方法,学生将具备必要的技能,以驾驭现代网络-物理-社会系统(CPSS)驱动的行业的复杂性。本文提供了一个案例研究,以展示框架的实施及其在促进跨学科控制研究和课程开发方面的潜力,突出iSTREAMS和iCDIOS在提高教育成果方面的协同作用。
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引用次数: 0
Adapting an Industrial Control Laboratory for Remote Access⁎ 适应远程访问的工业控制实验室
Q3 Engineering Pub Date : 2025-01-01 DOI: 10.1016/j.ifacol.2025.08.023
Gabriel Conde , Luis de la Torre , Raquel Dormido , Sebastián Dormido
Laboratory-based learning plays a crucial role in engineering education, especially in fields like automation and control. However, traditional industrial training labs often face challenges in terms of both realism and accessibility, limiting students’ exposure to real-world systems. In this paper, we present the transformation of a complex industrial process control plant into a fully remote-operable laboratory. By integrating new advanced hardware elements, we have enabled remote monitoring and control of the system. These modifications offer students industry-level realism and hands-on experience in industrial automation, accessible from any location. This work demonstrates the potential of the industrial remote lab to enhance engineering education by providing a flexible and realistic learning environment.
基于实验室的学习在工程教育中起着至关重要的作用,特别是在自动化和控制等领域。然而,传统的工业培训实验室经常面临现实主义和可访问性方面的挑战,限制了学生接触现实世界系统的机会。在本文中,我们提出了一个复杂的工业过程控制工厂转变为一个完全可远程操作的实验室。通过集成新的先进硬件元素,我们实现了对系统的远程监控。这些修改为学生提供了工业级的现实主义和工业自动化的实践经验,可以从任何地方访问。这项工作证明了工业远程实验室通过提供灵活和现实的学习环境来增强工程教育的潜力。
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引用次数: 0
Neural Operator based Reinforcement Learning for Control of first-order PDEs with Spatially-Varying State Delay⁎ 基于神经算子的一阶状态时滞微分方程的强化学习控制[j]
Q3 Engineering Pub Date : 2025-01-01 DOI: 10.1016/j.ifacol.2025.08.085
Jiaqi Hu , Jie Qi , Jing Zhang
Control of distributed parameter systems affected by delays is a challenging task, particularly when the delays depend on spatial variables. The idea of integrating analytical control theory with learning-based control within a unified control scheme is becoming increasingly promising and advantageous. In this paper, we design a integrated control strategy combining PDE backstepping and deep reinforcement learning (RL) for an unstable first-order hyperbolic PDE with spatially-varying delays. This method eliminates extra constraint on the delay function required for the backstepping design. We embed a DeepONet, trained to learn the backstepping controller, into a soft actor-critic (SAC) framework as a feature extractor for both the actor and critic networks. Simulation results demonstrate that the proposed algorithm outperforms standard SAC in reducing steady-state error and surpasses the backstepping controller in mitigating overshoot.
受延迟影响的分布参数系统的控制是一项具有挑战性的任务,特别是当延迟依赖于空间变量时。将分析控制理论与基于学习的控制结合在一个统一的控制方案中的想法正变得越来越有前途和优势。针对一类具有空间变化时滞的不稳定一阶双曲PDE,设计了一种结合PDE反演和深度强化学习(RL)的集成控制策略。该方法消除了反推设计对延迟函数的额外约束。我们将一个DeepONet嵌入到一个软演员-评论家(SAC)框架中,作为演员和评论家网络的特征提取器。仿真结果表明,该算法在减小稳态误差方面优于标准SAC,在减小超调方面优于后退控制器。
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引用次数: 0
Polynomial Stability of an Elastic Plate with Dynamical Boundary Control 具有动态边界控制的弹性板的多项式稳定性
Q3 Engineering Pub Date : 2025-01-01 DOI: 10.1016/j.ifacol.2025.08.096
Yanan Sun , Qiong Zhang
This work studies the boundary feedback stabilization for an elastic thin plate, where one part of its boundary is clamped and the remaining free part is attached to a rigid body. The boundary feedback controls are applied to the free boundary. Given that the boundary of the domain may have corners, we introduce a proper abstract framework to analyze the well-posedness and estimate the resolvent. When the geometric control condition (GCC) holds, we prove a polynomial energy decay rate of t-1/2. For cases where GCC does not hold, we analyze the system on a rectangular domain with control applied to only one edge and obtain a slower decay rate t-1/3.
本文研究了弹性薄板的边界反馈稳定化问题,其中薄板的一部分边界被夹紧,剩余的自由部分附着在刚体上。边界反馈控制应用于自由边界。考虑到域的边界可能存在角点,我们引入了一个适当的抽象框架来分析域的适定性和估计解。当几何控制条件(GCC)成立时,我们证明了多项式能量衰减率为t-1/2。对于GCC不成立的情况,我们在矩形域上分析系统,只对一条边施加控制,并获得较慢的衰减率t-1/3。
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引用次数: 0
Stabilization for Variable Coefficients Rayleigh Beam Systems under Nonlinear Boundary Controls 非线性边界控制下变系数瑞利梁系统的镇定
Q3 Engineering Pub Date : 2025-01-01 DOI: 10.1016/j.ifacol.2025.08.064
Ming Xu , Yi Cheng , Xin Wang , Yuhu Wu
This article solves the boundary stabilization problem of variable coefficient Rayleigh beams by using nonlinear boundary feedback controls. The feedback mechanism incorporates a nonlinear function that adheres to a sector condition, thus encompassing a diverse array of nonlinear feedback scenarios. The well-posedness of the closed-loop system is completed by applying nonlinear semigroup theory. The exponential stability of the energy function of a closed-loop system is demonstrated by using the integral multiplier method.
本文采用非线性边界反馈控制方法解决了变系数瑞利梁的边界稳定问题。反馈机制包含了一个符合扇形条件的非线性函数,从而包含了多种非线性反馈场景。利用非线性半群理论完成了闭环系统的适定性。利用积分乘数法证明了闭环系统能量函数的指数稳定性。
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引用次数: 0
Nonlinear Observer Design for an Undamped Wave Equation with Distributed Disturbance 具有分布扰动的无阻尼波动方程非线性观测器设计
Q3 Engineering Pub Date : 2025-01-01 DOI: 10.1016/j.ifacol.2025.08.073
Alexander Schaum , Stefan Koch
This paper addresses the design of a nonlinear observer for an undamped wave equation with distributed disturbance and pointwise position measurement at the boundary. Using the sliding-mode based robust exact differentiator, the velocity at the boundary is estimated. Based on this estimate, a standard Luenberger observer is designed for the nominal, i.e., undisturbed system, and robust convergence is ensured in the presence of bounded distributed disturbances that are constant in time, by adequately combining this observer with an algebraic correction. The proposed design approach achieves exponential convergence of the observer and, for special observer gains, even ensures finite-time convergence. The approach is illustrated using numerical simulations for a representative case study.
本文讨论了具有分布扰动的无阻尼波动方程的非线性观测器的设计和边界处的点向位置测量。利用基于滑模的鲁棒精确微分器,估计了边界处的速度。基于这一估计,为标称的即无扰动系统设计了标准Luenberger观测器,并且通过将该观测器与代数校正充分结合,确保了在时间恒定的有界分布扰动存在下的鲁棒收敛。提出的设计方法实现了观测器的指数收敛,对于特殊的观测器增益,甚至保证了有限时间的收敛。该方法是用数值模拟的代表性案例研究说明。
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引用次数: 0
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IFAC-PapersOnLine
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