Pub Date : 2016-07-01DOI: 10.11138/orl/2016.9.3.099
G. Mancini, A. Giannì, F. Cura, Z. Ormanier, F. Carinci
PURPOSE The aim of the present study is to evaluate the effectiveness of Ditron implants abutment connection (IAC) to sealing the gap between two pieces. MATERIALS AND METHODS To identify the efficacy of a new IAC, the passage of genetically modified bacteria across IAC was evaluated. A total of five Ditron Implants were used. All implants were immerged in a bacterial culture for forty-eight hours and then bacteria amount was measured inside and outside IAC with Real-time PCR. Bacterial quantification was performed by Real-Time Polymerase Chain Reaction using the absolute quantification with the standard curve method. RESULTS In all the tested implants, bacteria were found in the inner side, with a median percentage of 1.35%. The analysis revealed that, in untreated implants, bacteria grew (internally and externally). Moreover, the difference between outer and inner bacteria concentration was statistically significant at each time point. CONCLUSIONS Ditron Implant IAC (MPI, Ditron Dental, Israel) is efficacy in reducing bacterial leakage.
{"title":"Efficacy of a new implant-abutment connection to minimize microbial contamination: an in vitro study.","authors":"G. Mancini, A. Giannì, F. Cura, Z. Ormanier, F. Carinci","doi":"10.11138/orl/2016.9.3.099","DOIUrl":"https://doi.org/10.11138/orl/2016.9.3.099","url":null,"abstract":"PURPOSE\u0000The aim of the present study is to evaluate the effectiveness of Ditron implants abutment connection (IAC) to sealing the gap between two pieces.\u0000\u0000\u0000MATERIALS AND METHODS\u0000To identify the efficacy of a new IAC, the passage of genetically modified bacteria across IAC was evaluated. A total of five Ditron Implants were used. All implants were immerged in a bacterial culture for forty-eight hours and then bacteria amount was measured inside and outside IAC with Real-time PCR. Bacterial quantification was performed by Real-Time Polymerase Chain Reaction using the absolute quantification with the standard curve method.\u0000\u0000\u0000RESULTS\u0000In all the tested implants, bacteria were found in the inner side, with a median percentage of 1.35%. The analysis revealed that, in untreated implants, bacteria grew (internally and externally). Moreover, the difference between outer and inner bacteria concentration was statistically significant at each time point.\u0000\u0000\u0000CONCLUSIONS\u0000Ditron Implant IAC (MPI, Ditron Dental, Israel) is efficacy in reducing bacterial leakage.","PeriodicalId":38303,"journal":{"name":"ORAL and Implantology","volume":"9 3 1","pages":"99-105"},"PeriodicalIF":0.0,"publicationDate":"2016-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"63487899","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-07-01DOI: 10.11138/orl/2016.9.3.151
M. Miranda, L. Martínez, R. Franco, V. Forte, A. Barlattani, P. Bollero
The oral anticoagulant therapy is used for the cure and the prevention of thromboembolic diseases. In the last fifty years the warfarin has been considered the oral anticoagulant of choice. However, its use is limited by a narrow therapeutic index and by a complex pharmacodynamics, which requires regular adjustments and monitoring of the dose. Recently, three new oral anticoagulant - dabigatran etexilato (direct thrombin inhibitor), rivaroxaban and apixaban (Xa factor direct inhibitor) - have been approved for use in europe. Increasing the number of patients taking these drugs, it is important that the dentist knows these new oral anticoagulants, their indications and methods of action, in particular for the management of patients, who require invasive treatments. With regard to the management of the patient threated with the new oral anticoagulants (NAO), there have been new significant changes in the procedure compared to the one followed by patients treated with warfarin. This led to the development of new guidelines that the dentist has to follow in order to ensure a safe and appropriate dental treatment and reduce any postoperative complications. The aim of this work is to evaluate the effectiveness of the new oral anticoagulants compared to warfarin, especially in terms of risks of bleeding events and intra and postoperative complications, in patients requiring multiple dental extractions.
{"title":"Differences between warfarin and new oral anticoagulants in dental clinical practice.","authors":"M. Miranda, L. Martínez, R. Franco, V. Forte, A. Barlattani, P. Bollero","doi":"10.11138/orl/2016.9.3.151","DOIUrl":"https://doi.org/10.11138/orl/2016.9.3.151","url":null,"abstract":"The oral anticoagulant therapy is used for the cure and the prevention of thromboembolic diseases. In the last fifty years the warfarin has been considered the oral anticoagulant of choice. However, its use is limited by a narrow therapeutic index and by a complex pharmacodynamics, which requires regular adjustments and monitoring of the dose. Recently, three new oral anticoagulant - dabigatran etexilato (direct thrombin inhibitor), rivaroxaban and apixaban (Xa factor direct inhibitor) - have been approved for use in europe. Increasing the number of patients taking these drugs, it is important that the dentist knows these new oral anticoagulants, their indications and methods of action, in particular for the management of patients, who require invasive treatments. With regard to the management of the patient threated with the new oral anticoagulants (NAO), there have been new significant changes in the procedure compared to the one followed by patients treated with warfarin. This led to the development of new guidelines that the dentist has to follow in order to ensure a safe and appropriate dental treatment and reduce any postoperative complications. The aim of this work is to evaluate the effectiveness of the new oral anticoagulants compared to warfarin, especially in terms of risks of bleeding events and intra and postoperative complications, in patients requiring multiple dental extractions.","PeriodicalId":38303,"journal":{"name":"ORAL and Implantology","volume":"9 3 1","pages":"151-156"},"PeriodicalIF":0.0,"publicationDate":"2016-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.11138/orl/2016.9.3.151","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"63488089","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-07-01DOI: 10.11138/orl/2016.9.3.106
M. Lopez, M. Andreasi Bassi, L. Confalone, F. Silvestre, C. Arcuri
PURPOSE The aim of the present study is to demonstrate the efficacy of HyBeNX® to decontaminate the implant surface, both in the case mucositis and severe peri-implantitis and to allow future bone regeneration. MATERIALS AND METHODS We describe three case reports of peri-implantitis successfully treated with HyBeNX®. In our study, we have used microbiological tests to demonstrate the efficacy of HyBeNX® in decreasing bacterial load. RESULTS The microbiological results of the clinical cases described show that there was a reduction in the total bacterial count after treatment. CONCLUSIONS The ability of HyBeNX® to dry the surface and remove biofilm may explain the efficacy of the decontamination and subsequent clinical improvements in all three cases.
{"title":"The treatment of peri-implant diseases: a new approach using hybenx® as a decontaminant for implant surface and oral tissues.","authors":"M. Lopez, M. Andreasi Bassi, L. Confalone, F. Silvestre, C. Arcuri","doi":"10.11138/orl/2016.9.3.106","DOIUrl":"https://doi.org/10.11138/orl/2016.9.3.106","url":null,"abstract":"PURPOSE\u0000The aim of the present study is to demonstrate the efficacy of HyBeNX® to decontaminate the implant surface, both in the case mucositis and severe peri-implantitis and to allow future bone regeneration.\u0000\u0000\u0000MATERIALS AND METHODS\u0000We describe three case reports of peri-implantitis successfully treated with HyBeNX®. In our study, we have used microbiological tests to demonstrate the efficacy of HyBeNX® in decreasing bacterial load.\u0000\u0000\u0000RESULTS\u0000The microbiological results of the clinical cases described show that there was a reduction in the total bacterial count after treatment.\u0000\u0000\u0000CONCLUSIONS\u0000The ability of HyBeNX® to dry the surface and remove biofilm may explain the efficacy of the decontamination and subsequent clinical improvements in all three cases.","PeriodicalId":38303,"journal":{"name":"ORAL and Implantology","volume":"9 3 1","pages":"106-114"},"PeriodicalIF":0.0,"publicationDate":"2016-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.11138/orl/2016.9.3.106","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"63487916","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-07-01DOI: 10.11138/orl/2016.9.3.143
M. Andreasi Bassi, C. Andrisani, S. Lico, F. Silvestre, M. Gargari, C. Arcuri
PURPOSE The aim of this article is to make a comparative assessment between the modification of the soft-tissue profile, around the healing cap screws (HCSs), following both the traditional flapless surgery (TFS) and a new modified flapless surgery, named Modified Connective Tissue Punch (MCTP) technique. MATERIALS AND METHODS 8 patients (3M and 5F) (mean age 54.25±11.247 years) were enrolled in this study. Sixteen two-piece implants were placed on upper jaws, 2 for each patient, 8 with TFS and 8 with MCTP technique. In each patient the implants were placed in edentulous areas, of 2 or 3 adjacent teeth long. MCTP technique was performed on the front implant site (FIS) while the TFS was performed on the rear implant site (RIS). All implants were inserted and covered with healing cap screws (HCSs). Alginate impressions were carried out at the moment of the surgery, at 1 month and 4 months post-operative. Plaster models were poured and subsequently digitally scanned, in order to measure the distance between the gingival outline and the free margin of the HCS. The recorded values were analyzed with the ANOVA test. RESULTS The use of MTCP technique, in comparison to TFS, showed a significative better outcome, in terms of vertical increments, of gingiva, on the VS toward the HCSs, during the entire observation period (p = 0.000 for all). CONCLUSION The Authors recommend the use of MCTP technique for a better vestibular soft tissue outcome in flapless implant surgery.
{"title":"Increasing volume of vestibular soft tissues in flapless implant surgery through a modified connective punch technique: a controlled clinical trial.","authors":"M. Andreasi Bassi, C. Andrisani, S. Lico, F. Silvestre, M. Gargari, C. Arcuri","doi":"10.11138/orl/2016.9.3.143","DOIUrl":"https://doi.org/10.11138/orl/2016.9.3.143","url":null,"abstract":"PURPOSE\u0000The aim of this article is to make a comparative assessment between the modification of the soft-tissue profile, around the healing cap screws (HCSs), following both the traditional flapless surgery (TFS) and a new modified flapless surgery, named Modified Connective Tissue Punch (MCTP) technique.\u0000\u0000\u0000MATERIALS AND METHODS\u00008 patients (3M and 5F) (mean age 54.25±11.247 years) were enrolled in this study. Sixteen two-piece implants were placed on upper jaws, 2 for each patient, 8 with TFS and 8 with MCTP technique. In each patient the implants were placed in edentulous areas, of 2 or 3 adjacent teeth long. MCTP technique was performed on the front implant site (FIS) while the TFS was performed on the rear implant site (RIS). All implants were inserted and covered with healing cap screws (HCSs). Alginate impressions were carried out at the moment of the surgery, at 1 month and 4 months post-operative. Plaster models were poured and subsequently digitally scanned, in order to measure the distance between the gingival outline and the free margin of the HCS. The recorded values were analyzed with the ANOVA test.\u0000\u0000\u0000RESULTS\u0000The use of MTCP technique, in comparison to TFS, showed a significative better outcome, in terms of vertical increments, of gingiva, on the VS toward the HCSs, during the entire observation period (p = 0.000 for all).\u0000\u0000\u0000CONCLUSION\u0000The Authors recommend the use of MCTP technique for a better vestibular soft tissue outcome in flapless implant surgery.","PeriodicalId":38303,"journal":{"name":"ORAL and Implantology","volume":"9 3 1","pages":"143-150"},"PeriodicalIF":0.0,"publicationDate":"2016-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.11138/orl/2016.9.3.143","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"63488081","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-07-01DOI: 10.11138/orl/2016.9.3.132
L. Lombardo, F. Carinci, Mauro Martini, D. Gemmati, M. Nardone, G. Siciliani
PURPOSE This study had the aim of comparing two different methods of analysing dentin sialoprotein (DSP) in the gingival crevicular fluid (GCF): the conventional eLISA approach and a new method involving the use of magnetic micro-beads coated with an antibody specific for DSP prior to eLISA analysis. MATERIALS AND METHODS GCF was taken from six patients following twelve weeks of orthodontic treatment using paper strips inserted into the mesial and distal sulci of the upper incisors, and analysed using both methods. RESULTS Statistical analysis of the results using the Mann-Whitney non-parametric test showed that the micro-bead approach conferred more reliability and less variability on the conventional eLISA approach. Furthermore, this method, for the first time, enables the quantification of the DSP in the sample in ng/μl. CONCLUSIONS The innovative micro-bead/eLISA approach proposed provides a reliable means of quantifying the DSP in the GCF.
{"title":"Quantitive evaluation of dentin sialoprotein (DSP) using microbeads - a potential early marker of root resorption.","authors":"L. Lombardo, F. Carinci, Mauro Martini, D. Gemmati, M. Nardone, G. Siciliani","doi":"10.11138/orl/2016.9.3.132","DOIUrl":"https://doi.org/10.11138/orl/2016.9.3.132","url":null,"abstract":"PURPOSE\u0000This study had the aim of comparing two different methods of analysing dentin sialoprotein (DSP) in the gingival crevicular fluid (GCF): the conventional eLISA approach and a new method involving the use of magnetic micro-beads coated with an antibody specific for DSP prior to eLISA analysis.\u0000\u0000\u0000MATERIALS AND METHODS\u0000GCF was taken from six patients following twelve weeks of orthodontic treatment using paper strips inserted into the mesial and distal sulci of the upper incisors, and analysed using both methods.\u0000\u0000\u0000RESULTS\u0000Statistical analysis of the results using the Mann-Whitney non-parametric test showed that the micro-bead approach conferred more reliability and less variability on the conventional eLISA approach. Furthermore, this method, for the first time, enables the quantification of the DSP in the sample in ng/μl.\u0000\u0000\u0000CONCLUSIONS\u0000The innovative micro-bead/eLISA approach proposed provides a reliable means of quantifying the DSP in the GCF.","PeriodicalId":38303,"journal":{"name":"ORAL and Implantology","volume":"9 3 1","pages":"132-142"},"PeriodicalIF":0.0,"publicationDate":"2016-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.11138/orl/2016.9.3.132","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"63488506","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-04-01DOI: 10.11138/orl/2016.9.2.054
A. Lucchese, A. Dolci, G. Minervini, C. Salerno, D. Di Stasio, L. Laino, F. Silvestre, R. Serpico
PURPOSE Oral Lichen Planus (OLP) is a chronic inflammatory disease of skin and mucous membranes. Approximately 20% of women with oral lichen planus develops lesions in the genital mucosa. In 1982, Pelisse described a special form of lichen planus (LP), which consists of a triad of symptoms: vulval, vaginal and gingival (VVG)-LP lesions. Aim of the present report is to report two new cases and review the international literature. MATERIAL AND METHODS Two cases of VVG-LP are reported and a review of recent literature is performed. RESULTS The onset of erosive or ulcerative mouth lesions may precede or follow by months or even years the onset of vulvovaginal lesions. Vaginal agglutination is associated with the postmenopausal state in conjunction with a dermatologic condition. Intra-lesional corticosteroids have a role in localized chronic ulceration, while systemic therapies such as corticosteroids, azathioprine, mycophenolate mofetil, hydroxychloroquine, ciclosporin, methotrexate, retinoids, thalidomide and photo chemotherapy have been used in more severe cases with varying success. CONCLUSIONS VVG-LP is rather a rare condition and has been documented in the literature mainly in the form of case reports. Lack of a precise diagnostic criteria of VVG-LP depends on the specialists.
{"title":"Vulvovaginal gingival lichen planus: report of two cases and review of literature.","authors":"A. Lucchese, A. Dolci, G. Minervini, C. Salerno, D. Di Stasio, L. Laino, F. Silvestre, R. Serpico","doi":"10.11138/orl/2016.9.2.054","DOIUrl":"https://doi.org/10.11138/orl/2016.9.2.054","url":null,"abstract":"PURPOSE\u0000Oral Lichen Planus (OLP) is a chronic inflammatory disease of skin and mucous membranes. Approximately 20% of women with oral lichen planus develops lesions in the genital mucosa. In 1982, Pelisse described a special form of lichen planus (LP), which consists of a triad of symptoms: vulval, vaginal and gingival (VVG)-LP lesions. Aim of the present report is to report two new cases and review the international literature.\u0000\u0000\u0000MATERIAL AND METHODS\u0000Two cases of VVG-LP are reported and a review of recent literature is performed.\u0000\u0000\u0000RESULTS\u0000The onset of erosive or ulcerative mouth lesions may precede or follow by months or even years the onset of vulvovaginal lesions. Vaginal agglutination is associated with the postmenopausal state in conjunction with a dermatologic condition. Intra-lesional corticosteroids have a role in localized chronic ulceration, while systemic therapies such as corticosteroids, azathioprine, mycophenolate mofetil, hydroxychloroquine, ciclosporin, methotrexate, retinoids, thalidomide and photo chemotherapy have been used in more severe cases with varying success.\u0000\u0000\u0000CONCLUSIONS\u0000VVG-LP is rather a rare condition and has been documented in the literature mainly in the form of case reports. Lack of a precise diagnostic criteria of VVG-LP depends on the specialists.","PeriodicalId":38303,"journal":{"name":"ORAL and Implantology","volume":"9 2 1","pages":"54-60"},"PeriodicalIF":0.0,"publicationDate":"2016-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.11138/orl/2016.9.2.054","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"63487717","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-04-01DOI: 10.11138/orl/2016.9.2.083
A. Lucchese, A. Guida, G. Capone, G. Donnarumma, L. Laino, M. Petruzzi, R. Serpico, F. Silvestre, M. Gargari
PURPOSE To identify potential antigenic targets for Porphyromonas gingivalis vaccine development. MATERIALS AND METHODS In the present study, we analyzed the Porphyromonas gingivalis, fimA type II primary amino acid sequence and characterized the similarity to the human proteome at the pentapeptide level. RESULTS We found that exact peptide-peptide profiling of the fimbrial antigen versus the human proteome shows that only 19 out of 344 fimA type II pentapeptides are uniquely owned by the bacterial protein. CONCLUSIONS The concept that protein immunogenicity is allocated in rare peptide sequences and the search the Porphyromonas gingivalis fimA type II sequence for peptides unique to the bacterial protein and absent in the human host, might be used in new therapeutical approaches as a significant adjunct to current periodontal therapies.
{"title":"Proteomic peptide scan of porphyromonas gingivalis fima type ii for searching potential b-cell epitopes.","authors":"A. Lucchese, A. Guida, G. Capone, G. Donnarumma, L. Laino, M. Petruzzi, R. Serpico, F. Silvestre, M. Gargari","doi":"10.11138/orl/2016.9.2.083","DOIUrl":"https://doi.org/10.11138/orl/2016.9.2.083","url":null,"abstract":"PURPOSE\u0000To identify potential antigenic targets for Porphyromonas gingivalis vaccine development.\u0000\u0000\u0000MATERIALS AND METHODS\u0000In the present study, we analyzed the Porphyromonas gingivalis, fimA type II primary amino acid sequence and characterized the similarity to the human proteome at the pentapeptide level.\u0000\u0000\u0000RESULTS\u0000We found that exact peptide-peptide profiling of the fimbrial antigen versus the human proteome shows that only 19 out of 344 fimA type II pentapeptides are uniquely owned by the bacterial protein.\u0000\u0000\u0000CONCLUSIONS\u0000The concept that protein immunogenicity is allocated in rare peptide sequences and the search the Porphyromonas gingivalis fimA type II sequence for peptides unique to the bacterial protein and absent in the human host, might be used in new therapeutical approaches as a significant adjunct to current periodontal therapies.","PeriodicalId":38303,"journal":{"name":"ORAL and Implantology","volume":"9 2 1","pages":"83-88"},"PeriodicalIF":0.0,"publicationDate":"2016-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"63487815","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-04-01DOI: 10.11138/orl/2016.9.2.076
Elias El Haddad, A. Giannì, G. Mancini, F. Cura, F. Carinci
PURPOSE The aim of our study is to value the microbial contamination in the implant-abutment connections (IAC) of a Nobel Replace Conical Connection implant system [Nobel Biocare®, Vimercate (MB), Italy]. MATERIALS AND METHODS To identify the capability of the implant to protect the internal space from the external environment, the passage of genetically modified bacteria across IAC was evaluated. Four Nobel Replace Conical Connection implants (Nobel Biocare®, Vimercate (MB), Italy) were immerged in a bacterial culture for twenty-four hours and then bacteria amount was measured inside and outside IAC with Real-time PCR. Bacterial quantification was performed by Real-Time Polymerase Chain Reaction using the absolute quantification with the standard curve method. RESULTS In all tested implants, bacteria were found in the inner side, with a median percentage of 10.9%. The analysis revealed that in both cases (internally and externally), bacteria grew for the first 48 hours but subsequently they started to dye, probably as a consequence of nutrient consumption. Moreover, the difference between outer and inner bacteria concentration was statistically significant at each time point. CONCLUSIONS Implant's internal contamination shows that IAC is not sealing. The reported results are similar to those of previous studies carried out on different implant systems. Until now, no IAC has been proven to seal the gap between implant and abutment.
{"title":"Implant-abutment leaking of replace conical connection nobel biocare® implant system. An in vitro study of the microbiological penetration from external environment to implant-abutment space.","authors":"Elias El Haddad, A. Giannì, G. Mancini, F. Cura, F. Carinci","doi":"10.11138/orl/2016.9.2.076","DOIUrl":"https://doi.org/10.11138/orl/2016.9.2.076","url":null,"abstract":"PURPOSE\u0000The aim of our study is to value the microbial contamination in the implant-abutment connections (IAC) of a Nobel Replace Conical Connection implant system [Nobel Biocare®, Vimercate (MB), Italy].\u0000\u0000\u0000MATERIALS AND METHODS\u0000To identify the capability of the implant to protect the internal space from the external environment, the passage of genetically modified bacteria across IAC was evaluated. Four Nobel Replace Conical Connection implants (Nobel Biocare®, Vimercate (MB), Italy) were immerged in a bacterial culture for twenty-four hours and then bacteria amount was measured inside and outside IAC with Real-time PCR. Bacterial quantification was performed by Real-Time Polymerase Chain Reaction using the absolute quantification with the standard curve method.\u0000\u0000\u0000RESULTS\u0000In all tested implants, bacteria were found in the inner side, with a median percentage of 10.9%. The analysis revealed that in both cases (internally and externally), bacteria grew for the first 48 hours but subsequently they started to dye, probably as a consequence of nutrient consumption. Moreover, the difference between outer and inner bacteria concentration was statistically significant at each time point.\u0000\u0000\u0000CONCLUSIONS\u0000Implant's internal contamination shows that IAC is not sealing. The reported results are similar to those of previous studies carried out on different implant systems. Until now, no IAC has been proven to seal the gap between implant and abutment.","PeriodicalId":38303,"journal":{"name":"ORAL and Implantology","volume":"9 2 1","pages":"76-82"},"PeriodicalIF":0.0,"publicationDate":"2016-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.11138/orl/2016.9.2.076","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"63487807","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-04-01DOI: 10.11138/orl/2016.9.2.089
M. Lopez, S. Lico, M. Casale, Z. Ormanier, Francesco Carinci
PURPOSE In the context of the transcrestal maxillary sinus lift a wide variety of biomaterials have been used to fill the subantral space over the years. In this study, two types of biomaterials were used in order to fill the maxillary sinus: a nano-crystallized hydroxyapatite in an aqueous solution and a micronized heterologous bone in a collagen matrix. MATERIALS AND METHODS The surgical procedures were designed and carried out using computer-guided surgery. The filling volume obtained was measured with a comparative software program. RESULTS A ≥ 6 millimeter augmentation of osseous volume was obtained. This result is comparable to those obtained in lifts where conventional techniques were applied. The technique used was very precise and the difference between the projected and clinical outcome of the implant position had an average of less than 0.3 millimeters. CONCLUSIONS This technique allows for the surgery to be performed in a way which is both minimally traumatic and invasive, and represents a viable alternative to those surgical techniques for crestal sinus lift currently in use.
{"title":"The use of various biomaterials in computer-guided crestal sinus lift procedures. A report on two case studies with volume comparison.","authors":"M. Lopez, S. Lico, M. Casale, Z. Ormanier, Francesco Carinci","doi":"10.11138/orl/2016.9.2.089","DOIUrl":"https://doi.org/10.11138/orl/2016.9.2.089","url":null,"abstract":"PURPOSE\u0000In the context of the transcrestal maxillary sinus lift a wide variety of biomaterials have been used to fill the subantral space over the years. In this study, two types of biomaterials were used in order to fill the maxillary sinus: a nano-crystallized hydroxyapatite in an aqueous solution and a micronized heterologous bone in a collagen matrix.\u0000\u0000\u0000MATERIALS AND METHODS\u0000The surgical procedures were designed and carried out using computer-guided surgery. The filling volume obtained was measured with a comparative software program.\u0000\u0000\u0000RESULTS\u0000A ≥ 6 millimeter augmentation of osseous volume was obtained. This result is comparable to those obtained in lifts where conventional techniques were applied. The technique used was very precise and the difference between the projected and clinical outcome of the implant position had an average of less than 0.3 millimeters.\u0000\u0000\u0000CONCLUSIONS\u0000This technique allows for the surgery to be performed in a way which is both minimally traumatic and invasive, and represents a viable alternative to those surgical techniques for crestal sinus lift currently in use.","PeriodicalId":38303,"journal":{"name":"ORAL and Implantology","volume":"9 2 1","pages":"89-97"},"PeriodicalIF":0.0,"publicationDate":"2016-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.11138/orl/2016.9.2.089","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"63487827","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-04-01DOI: 10.11138/orl/2016.9.2.049
A. Rosa, M. Miranda, R. Franco, M. Guarino, A. Barlattani, P. Bollero
Hereditary angioedema (HAE) is a rare disease, little known to the medical and dental community, but with a growing rate of hospitalization over the years. HAE is due to a deficit/dysfunction of C1 esterase inhibitor which leads to an increase in vascular permeability and the appearance of edemas widespread in all body areas. The airways are the most affected and laryngeal swelling, which can occur, it is dangerous for the patient's life, is also a sensitive spot in our daily practice, therefore, it is also important to be aware of all the signs of this disease. Episodes of HAE have no obvious cause, but it can be triggered by anxiety, invasive procedures and trauma. So this disease is a major problem in oral and maxillofacial surgery, ENT, endoscopy, emergency medicine and anesthesia because even simple procedures can cause laryngeal edema. The recommendations on the management of HAE include long- and short-term prophylaxis and treatment for acute attacks, however, the importance of anxiety control during the operating phases is undervalued. The present work suggests an experimental protocol for the surgery management of HAE patients with the help of nitrous oxide, with a brief review of the literature on this topic.
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