Journal of Conservative Dentistry最新文献

Context: Endodontic retreatment is the first line of treatment in cases of failed primary endodontic treatment. Although associated with challenges such as incomplete removal of obturating material, increased clinical time, and extrusion of apical debris, endodontic retreatment still has considerable success rate in the general population.

Aims: The aim of this study was to evaluate and compare the efficacy of TruNatomy, ProTaper retreatment, and RaCe file systems to remove the obturating material, time taken to remove the obturating material, and apical extrusion of debris using cone-beam computed tomography (CBCT).

Settings and design: In vitro study.

Subjects and methods: Forty-five moderately curved mesiobuccal roots of the mandibular molars were instrumented up to #25, 4% taper and obturated with bioceramic sealer and lateral compaction technique. Teeth were divided randomly into three groups (n = 15). Teeth were retreated with TruNatomy, ProTaper retreatment, and RaCe file systems, respectively. Preretreatment and postretreatment CBCT scans were recorded and percentage of obturating material removed was calculated. Time taken to remove the obturating material and apical extrusion of debris was noted.

Statistical analysis used: Descriptive statistics including percentage, mean, standard deviation, Tukey's post hoc test, Kruskal-Wallis test, and Mann-Whitney Post hoc test were used.

Results: The total time needed for the removal of obturating material was comparatively shorter in the RaCe group, followed by the ProTaper retreatment group and TruNatomy group (P < 0.001). TruNatomy files were significantly better in removing the obturating material than the ProTaper retreatment files (P = 0.04). Statically, no difference between RaCe and TruNatomy files was noted. Apically extruded debris was more in the TruNatomy group than in the RaCe and ProTaper retreatment groups (P = 0.01).

Conclusions: All tested endodontic files were effective in removal of obturating material, although none could completely remove the filling material and no system could completely eliminate apical extrusion.

Background: Cavity preparation often causes gingival bleeding which can be controlled by hemostatic agents (HAs). These along with blood act as contaminants and hamper the bonding mechanism. Collagen cross-linkers (CCLs) are agents known to increase the bond strength (BS) to dentin. Hence, the purpose of this in vitro study was to determine the effect of two different CCLs, proanthocyanidin (grape seed extract [GSE]) and hesperidin on the microtensile BS (μTBS) of a self-etch adhesive (SEA) system to dentin which was contaminated with blood and a HA.

Materials and methods: Thirty-six extracted human molars were collected, and their occlusal surfaces were sectioned to expose the dentin. The teeth were randomly divided into four groups: Group I - Control, Group II - Contamination with blood and HA, Group III - Application of GSE after contamination, and Group IV - Application of hesperidin extract after contamination. The SEA was applied, followed by the use of a nanocomposite. Dentin-composite rods were obtained from each group, and μTBS testing was done. The fracture pattern was visually classified as an adhesive failure at the interface, cohesive failure in composite, or dentin. The scanning electron microscope (SEM) analysis was done for two samples from each group. Statistical analysis was done using the Student's unpaired "t" and ANOVA test.

Results: Group II showed a statistically significant reduction in μTBS in comparison to Group I. This was overcome in Groups III and IV. Hesperidin showed marginally better results than GSE.

Conclusions: The use of GSE and hesperidin increases the μTBS of composite resin to dentin postcontamination with blood and ViscoStat Clear with Single Bond Universal Adhesive.

Context: Adjuvant use of platelet-rich fibrin (PRF) in many areas of dentistry is well documented. However, its role in periapical surgery remains contested which requires further clarification by a higher level of evidence.

Aim: The objective of this systematic review was to evaluate the effect of PRF on periapical surgery using meta-analysis.

Materials and methods: A comprehensive literature search was conducted in PUBMED, Cochrane Central Register of Controlled Trials, SCIENCE DIRECT, and GOOGLE SCHOLAR for randomized controlled trials (RCT) published until May 2021. Meta-analysis was performed for comparisons of baseline (pretreatment) versus posttreatment values for different measurement parameters (postoperative pain, peri apical healing both qualitatively and quantitatively). The risk of bias in all the included trials was assessed after the recommendations of the Cochrane Handbook for Systematic Reviews of Interventions.

Results: Among the 356 eligible articles found in the initial search, 10 RCTs from 2011 through 2021 were included. Qualitative analysis of all the included studies showed that PRF may play a positive role in bone healing, reduction in periapical lesions, and enhancing quality of life using different imaging modalities. The results of the meta-analysis indicated a significant reduction in postoperative pain when PRF was used (standard mean difference [SMD] = 0.515; 95% confidence interval [CI] = 0.061- 0.969;P = 0.026; I 2 = 0%). However, there was no statistically significant association observed while evaluating peri apical bone healing both qualitatively (odds ratio [OR] = 1.427; 95% CI = 0.309-6.584; P = 0.648) and quantitatively measured by Cone beam computed tomography (SMD = -0.264; 95% CI = -0.974-0.447;P = 0.454) between PRF and control group.

Conclusions: Considering the notable benefits demonstrated by use of PRF, it may be considered as a valuable adjunct in periapical surgery. However, more high-quality trials are necessary to assess the exact role of PRF.

Introduction: The study evaluates and compare the effect of 3% warm NaOCl with NaOCl at room temperature in root canal irrigation on postoperative pain.

Materials and methods: In this randomized controlled trial, mandibular molars with symptomatic irreversible pulpitis in healthy 18-year-old patients and above were included. The sample consisted of 56 patients evaluating the postoperative pain, allocated randomly into 2 groups of 3% NaOCl at two different temperatures, i.e. at room temperature and at 60°C. Endodontic treatment was initiated for each group and instrumentation was done using MTwo rotary files. The final irrigation was performed according to the groups assigned. For each included tooth, preoperative and postoperative pain scores at 6, 12, 24, 48, and 72 h were collected through the Heft Parker Visual Analog Scale. Statistical analysis was performed using independent t-test, Chi-square test, Mann-Whitney U-test, and Friedman test followed by Wilcoxon test.

Results: The mean percentage reduction in pain scores was significantly higher among the warm NaOCl group as compared to the control group at different time intervals (P < 0.001). The mean number of analgesics taken was significantly lower among the warm NaOCl group as compared to the control group (P < 0.001).

Conclusion: The warm NaOCl group recorded less postoperative pain than the control group during the first 72 h following single-visit endodontic therapy.

[This retracts the article on p. 271 in vol. 26, PMID: 37398852.].

Objective: The objective of the study was to evaluate the effect of access cavity design on fracture resistance of the extracted maxillary first and second molars prepared with three minimally invasive files.

Materials and methods: One hundred and twelve extracted human maxillary molars were selected for the study and divided randomly into three groups according to different minimally invasive files used (self-adjusting files [SAF], XP-endo Shaper [XP], and 4 V-Taper 2H [VT]) and one control group (CG). All experimental groups were subdivided into two subgroups, i.e., conservative access cavity (CAC) and traditional access cavity (TAC). All the canals in different experimental groups were enlarged up to apical size 30. The data were analyzed using the analysis of variance and Post hoc Tukey tests (P < 0.05).

Results: The highest mean fracture resistance of teeth with CAC was of the CG (1399.957), followed by teeth with CAC instrumented by SAF (1378.314) and XP-endo Shaper (1202.929). The least value was of the V-Taper file system (937.157). Furthermore, the highest mean fracture resistance value of teeth with TAC was of the CG (1143.171), followed by teeth with TAC instrumented by SAF (1150.607) and then XP-endo Shaper (998.150). The least value was of the V Taper file system (757.050).

Conclusion: Conservative endodontic access (CAC) in the maxillary molars had shown significantly increased fracture resistance over TAC. SAF showed the maximum fracture resistance, while V-Taper files showed the least fracture resistance among the experimental groups compared.

Aim: The aim of this in vitro study was to measure the quality of marginal adaptation of three root end filling materials by scanning electron microscope (SEM).

Methodology: Thirty extracted human permanent single-rooted single canal maxillary anterior teeth with mature apices were prepared up to 60 K-file and obturated. Teeth were resected 3 mm from the apex using a cross-cut fissure bur at 90° angle to the long axis of the tooth. Root end cavities of 3 mm were prepared in each of the teeth with an ultrasonic tip to receive the root end filling material. Group 1 - mineral trioxide aggregate (MTA), Group 2 - Biodentine, and Group 3 - Geristore. The samples were mounted in resin blocks for sectioning with a hard-tissue microtome and sectioned apically at 1 mm and 2 mm levels from the apex. They were gold sputtered and viewed under SEM for evaluating the adaptation of the material to the canal walls.

Results: The mean value for Group II (Biodentine) was lower than the mean value for Group I (MTA) and Group III (Geristore) at 1 mm and 2 mm.

Conclusion: Biodentine showed significantly better marginal adaptation as compared to MTA and Geristore.

Aim: The aim of this study was to assess and compare the effect of ultrasonic and diode laser-activated sodium hypochlorite (NaOCl), chitosan, and chlorhexidine (CHX) on the removal of Enterococcus faecalis biofilm adherent to the root canal using a confocal laser scanning microscope (CLSM).

Materials and methods: Root canals in 112 single-rooted teeth were instrumented using a rotary Ni-Ti system. Biofilms of E. faecalis were generated based on an established protocol. Samples were randomly divided into three experimental (n = 28) and one control (n = 28) group based on the irrigation protocol employed and the three experimental groups were further subdivided into subgroups based on the activation protocol (subgroup A - ultrasonic activated and subgroup B - diode laser activated). The groups were Group 1 (control), Group 2 (3% NaOCl for 6 min; subgroup A - activated using a diode laser, subgroup B - ultrasonic activation), Group 3 (2% CHX for 6 min; subgroup A - activated using a diode laser, subgroup B - ultrasonic activation), and Group 4 (0.2% chitosan for 6 min; subgroup A - activated using a diode laser, subgroup B - ultrasonic activation. Confocal laser scanning microscopy was used to assess bacterial viability in situ. Data were analyzed by appropriate statistical analyses with P = 0.05.

Results: All experimental irrigation protocols destroyed the biofilm in the root canal lumen. Within the dentinal tubules, all groups had a significantly higher percentage of dead bacteria than the saline control (P < 0.05). There was no significant difference between CHX activated with ultrasonics, CHX activated with a diode laser, chitosan activated with ultrasonics and chitosan activated with diode laser groups (P > 0.05), whereas NaOCl ultra and NaOCl diode groups brought about more bacterial reduction than other groups (P < 0.05). The mean effectiveness and the bacterial kill ability were seen highest for the NaOCl activated with the ultrasonics group. There was no significant difference between diode laser activation and ultrasonic activation in CHX activated with ultrasonics, CHX activated with a diode laser, chitosan activated with ultrasonics and chitosan activated with diode laser groups (P > 0.05), but there was a significant difference between diode laser and ultrasonic activation in NaOCl group. Ultrasonic activation of the NaOCl was more effective than diode activation in reducing E. feacalis biofilms (P < 0.05).

Conclusions: The use of NaOCl with the activation by ultrasonics caused the greatest reduction of E. faecalis. Ultrasonic activation was found superior to diode laser activation in dentinal tubule disinfection.

Objective: This study evaluates the effects of immediate dentin sealing (IDS) on the fracture resistance of lithium disilicate overlays using three different types of resin-luting agents (preheated composite, dual-cure adhesive resin, and flowable composite).

Materials and methods: Forty-eight maxillary first premolars of equal size were prepared using a butt joint preparation design. The teeth were separated into two primary groups, each with 24 teeth: Group DDS - delay dentin sealing (DDS) (non-IDS) teeth were not treated. Group IDS - dentin sealing was applied immediately after teeth preparations. Each group was subsequently separated into three separate subgroups of eight teeth. Subgroups DDS+Phc and IDS+Phc - cemented with preheated composite (Enamel plus HRi, Micerium, Italy), subgroups DDS+Dcrs and IDS+Dcrs - cemented with dual-cured resin cement (RelyX Ultimate, 3M ESPE, Germany), and subgroups DDS+Fc and IDS+Fc - cemented with flowable composite (Filtek Supreme Flowable, 3M ESPE, USA). The fracture resistance of each sample was evaluated using a test of a single load till failure, which was automatically recorded in Newton by a computer-controlled universal testing system.

Results: The fracture resistance of the subgroup IDS+Phc was the highest mean value, in which the overlay was cemented with preheated composite (1954 N), and the lowest mean was noted in the subgroup DDS+Fc, by which the overlay cemented with flowable composite without IDS (887 N). All IDS subgroups had a high mean fracture load. Both the Bonferroni test and the one-way ANOVA test identified a significant difference between all groups of 0.05.

Conclusion: In general, teeth with IDS were stronger than teeth without IDS. When the preheated composite is used as a luting agent improves overall fracture resistance, followed by resin cement and flowable composite, respectively. However, the result showed that the ceramic overlays with and without IDS are strong enough to withstand the normal mastication force. Overlays was failed in a more catastrophic, irreparable mode of fracture than the clinical situation.