Pub Date : 2016-09-01DOI: 10.5005/JP-JOURNALS-10016-1137
Anjali Mundkur, Shalini S Nayak, A. Vasudeva, G. Katta, Pratap Kumar, K. Rao
{"title":"Congenital high airway obstruction syndrome presenting as nonimmune hydrops in a 19-week fetus","authors":"Anjali Mundkur, Shalini S Nayak, A. Vasudeva, G. Katta, Pratap Kumar, K. Rao","doi":"10.5005/JP-JOURNALS-10016-1137","DOIUrl":"https://doi.org/10.5005/JP-JOURNALS-10016-1137","url":null,"abstract":"","PeriodicalId":38998,"journal":{"name":"International Journal of Infertility and Fetal Medicine","volume":"4 1","pages":"99-102"},"PeriodicalIF":0.0,"publicationDate":"2016-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73799147","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-08-01DOI: 10.5005/JP-JOURNALS-10016-1130
P. Dahm-Kähler, M. Brännström
The clinical field of composite tissue transplantation now also includes uterus transplantation (UTx), a new type of quality-oflife enhancing and in this case also life-giving transplantation. The purpose of UTx is to enable live birth from a woman who lacks uterus or in a woman who has a defective uterus.
{"title":"Uterus Transplantation: An Update and Preparations for Introduction in India","authors":"P. Dahm-Kähler, M. Brännström","doi":"10.5005/JP-JOURNALS-10016-1130","DOIUrl":"https://doi.org/10.5005/JP-JOURNALS-10016-1130","url":null,"abstract":"The clinical field of composite tissue transplantation now also includes uterus transplantation (UTx), a new type of quality-oflife enhancing and in this case also life-giving transplantation. The purpose of UTx is to enable live birth from a woman who lacks uterus or in a woman who has a defective uterus.","PeriodicalId":38998,"journal":{"name":"International Journal of Infertility and Fetal Medicine","volume":"23 1","pages":"61-67"},"PeriodicalIF":0.0,"publicationDate":"2016-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80521772","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-08-01DOI: 10.5005/jp-journals-10016-1127
C. Chandana, C. Shankarappa
Background: To explore the association between ABO blood type and ovarian reserve, as reflected by early follicular phase follicle stimulating hormone (FSH) levels. Materials and methods: In this cross-sectional observational study, early follicular phase (day 3) serum levels of FSH (IU/L) and information on blood types (O, A, B, AB), patient age, and body mass index (BMI) were collected from 300 female patients, who were undergoing fertility evaluation at Vydehi Institute of Medical Sciences and Research Centre (VIMS & RC), Bengaluru. Serum FSH > 10 IU/L was taken as a measure of decreased ovarian reserve (DOR). Data distribution for FSH, age, BMI were analyzed and nonparametric tests were used for comparison across blood groups. Pearson’s correlation test was used to determine the relationship between elevated FSH and blood types after adjusting for age and BMI. Results: Proportions of blood types O, A, B, and AB were 42, 24.3, 28.7, and 5% respectively. Mean age (years) and BMI (kg/m2) among study group were 34.08 ± 3.48 and 24.34 ± 2.56 respectively. Out of 300 women, 240 women had serum FSH < 10 IU/L and 60 women had serum FSH > 10 IU/L. Women with blood type “O” (32 out of 60) were twice as likely to exhibit FSH > 10 IU/L (p = 0.02) compared to “A” and “B” blood type. Conclusion: Our results have shown that there is an association between ABO blood type and DOR among Indian women. Blood group “O” appears to be associated with DOR that is independent of advancing age and BMI.
{"title":"Implication of ABO Blood Type on Ovarian Reserve in Indian Women","authors":"C. Chandana, C. Shankarappa","doi":"10.5005/jp-journals-10016-1127","DOIUrl":"https://doi.org/10.5005/jp-journals-10016-1127","url":null,"abstract":"Background: To explore the association between ABO blood type and ovarian reserve, as reflected by early follicular phase follicle stimulating hormone (FSH) levels. Materials and methods: In this cross-sectional observational study, early follicular phase (day 3) serum levels of FSH (IU/L) and information on blood types (O, A, B, AB), patient age, and body mass index (BMI) were collected from 300 female patients, who were undergoing fertility evaluation at Vydehi Institute of Medical Sciences and Research Centre (VIMS & RC), Bengaluru. Serum FSH > 10 IU/L was taken as a measure of decreased ovarian reserve (DOR). Data distribution for FSH, age, BMI were analyzed and nonparametric tests were used for comparison across blood groups. Pearson’s correlation test was used to determine the relationship between elevated FSH and blood types after adjusting for age and BMI. Results: Proportions of blood types O, A, B, and AB were 42, 24.3, 28.7, and 5% respectively. Mean age (years) and BMI (kg/m2) among study group were 34.08 ± 3.48 and 24.34 ± 2.56 respectively. Out of 300 women, 240 women had serum FSH < 10 IU/L and 60 women had serum FSH > 10 IU/L. Women with blood type “O” (32 out of 60) were twice as likely to exhibit FSH > 10 IU/L (p = 0.02) compared to “A” and “B” blood type. Conclusion: Our results have shown that there is an association between ABO blood type and DOR among Indian women. Blood group “O” appears to be associated with DOR that is independent of advancing age and BMI.","PeriodicalId":38998,"journal":{"name":"International Journal of Infertility and Fetal Medicine","volume":"103 1","pages":"49-51"},"PeriodicalIF":0.0,"publicationDate":"2016-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78187271","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-08-01DOI: 10.5005/JP-JOURNALS-10016-1128
K. Gopinathan, A. Pillai, G. Parasuram, F. L. Thalakottoor
{"title":"Evaluation of the Role of Hysteroscopic Endometrial Injury and Its Timing Prior to in vitro Fertilization Treatment","authors":"K. Gopinathan, A. Pillai, G. Parasuram, F. L. Thalakottoor","doi":"10.5005/JP-JOURNALS-10016-1128","DOIUrl":"https://doi.org/10.5005/JP-JOURNALS-10016-1128","url":null,"abstract":"","PeriodicalId":38998,"journal":{"name":"International Journal of Infertility and Fetal Medicine","volume":"74 1","pages":"52-57"},"PeriodicalIF":0.0,"publicationDate":"2016-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84798456","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-08-01DOI: 10.5005/JP-JOURNALS-10016-1129
K. Nadkarni
Aim: To study unusual presentations of 46XY pure gonadal dysgenesis (Swyer syndrome), implications of delayed diagnosis, importance of karyotype and early gonadectomy and pregnancy outcome with ART. Background: To report a case of Swyer syndrome with spontaneous breast development, menses and bilateral hydrosalpinx with Successful pregnancy outcome. Case description: 30 years old lady presented with primary infertility, secondary amenorrhea and normal secondary sexual characters. Sonography revealed small uterus with atrophic ovaries and B/L hydrosalpinx. Hormonal profile showed hypergonadotrophic hypogonadism and Karyotype was 46XY. Laparoscopic salpingectomy and gonadectomy was done. Histopathology revealed streak gonads with no evidence of malignancy and diagnosis of 46XY disorder of sexual development (DSD)/ Swyer syndrome was made. After endometrial preparation with ethinyl estradiol, patient conceived with allogenic oocytes and delivered preterm twins vaginally at 31 weeks. Conclusion: Patients with Swyer Syndrome usually present at adolescence with delayed puberty and/or primary amenorrhea. However they can present late with secondary amenorrhea or just irregular, infrequent menses or primary infertility. Karyotype is mandatory in such cases and early gonadectomy improves long term survival as incidence of malignancy in the dysgenetic gonad is high. Incipient malignancy is usually the source of estrogen in patients with normal secondary sexual characters. Hypoplastic uterus is responsive to estrogen therapy in terms of enlargement and endometrial preparation and also this uterus may have the ability to respond to the process of labor and these patients can deliver vaginally. Clinical significance: Early diagnosis and timely management of patients with dysgenetic gonads is important. Pregnancy is possible with allogenic oocytes. Genetic counseling and long term follow-up is required. ijifm
{"title":"Successful Conception and Delivery in an Unusual Case of 46,XY Pure Gonadal Dysgenesis with Spontaneous Breast Development, Menses, and Bilateral Hydrosalpinx","authors":"K. Nadkarni","doi":"10.5005/JP-JOURNALS-10016-1129","DOIUrl":"https://doi.org/10.5005/JP-JOURNALS-10016-1129","url":null,"abstract":"Aim: To study unusual presentations of 46XY pure gonadal dysgenesis (Swyer syndrome), implications of delayed diagnosis, importance of karyotype and early gonadectomy and pregnancy outcome with ART. Background: To report a case of Swyer syndrome with spontaneous breast development, menses and bilateral hydrosalpinx with Successful pregnancy outcome. Case description: 30 years old lady presented with primary infertility, secondary amenorrhea and normal secondary sexual characters. Sonography revealed small uterus with atrophic ovaries and B/L hydrosalpinx. Hormonal profile showed hypergonadotrophic hypogonadism and Karyotype was 46XY. Laparoscopic salpingectomy and gonadectomy was done. Histopathology revealed streak gonads with no evidence of malignancy and diagnosis of 46XY disorder of sexual development (DSD)/ Swyer syndrome was made. After endometrial preparation with ethinyl estradiol, patient conceived with allogenic oocytes and delivered preterm twins vaginally at 31 weeks. Conclusion: Patients with Swyer Syndrome usually present at adolescence with delayed puberty and/or primary amenorrhea. However they can present late with secondary amenorrhea or just irregular, infrequent menses or primary infertility. Karyotype is mandatory in such cases and early gonadectomy improves long term survival as incidence of malignancy in the dysgenetic gonad is high. Incipient malignancy is usually the source of estrogen in patients with normal secondary sexual characters. Hypoplastic uterus is responsive to estrogen therapy in terms of enlargement and endometrial preparation and also this uterus may have the ability to respond to the process of labor and these patients can deliver vaginally. Clinical significance: Early diagnosis and timely management of patients with dysgenetic gonads is important. Pregnancy is possible with allogenic oocytes. Genetic counseling and long term follow-up is required. ijifm","PeriodicalId":38998,"journal":{"name":"International Journal of Infertility and Fetal Medicine","volume":"19 1","pages":"58-60"},"PeriodicalIF":0.0,"publicationDate":"2016-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81766132","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-08-01DOI: 10.5005/JP-JOURNALS-10016-1132
Nupur Garg, R. Govind, Smitha Avula
Pregnancy in women with systemic lupus erythematosus (SLE) or autoimmune conditions is complicated by complementmediated injury and is associated with increased risk of preeclampsia. Immunological intolerance between the mother and the fetus may play an important role in the pathogenesis of preeclampsia. The present case highlights the influence of susceptibility to preeclampsia/hemolysis, elevated liver enzyme levels, and low platelet levels (HELLP) syndrome due to preexisting autoimmune conditions. In vitro fertilization (IVF)Donor embryo pregnancy (DEM) pregnancy is one such unique scenario where there exists partial immunological disparity between the native intrauterine environment and the implanted donor embryo that could predispose to autoimmune problems in pregnancy. This case illustrates a similar scenario in which a pregnant woman with IVF-DEM conception and antinuclear antibody (ANA) positive status manifested with a normotensive partial HELLP syndrome which was reiterated by the fact that there was clinical evidence of retroperitoneal hemorrhage intraoperatively during cesarean along with the neonate who was diagnosed to have L-carnitine deficiency, which is unique to fetuses with mothers of HELLP syndrome.
{"title":"An Unusual Presentation of Partial Hemolysis, Elevated Liver Enzyme Levels, and Low Platelet Levels Syndrome in a Case of in vitro Fertilization-DEM Pregnancy","authors":"Nupur Garg, R. Govind, Smitha Avula","doi":"10.5005/JP-JOURNALS-10016-1132","DOIUrl":"https://doi.org/10.5005/JP-JOURNALS-10016-1132","url":null,"abstract":"Pregnancy in women with systemic lupus erythematosus (SLE) or autoimmune conditions is complicated by complementmediated injury and is associated with increased risk of preeclampsia. Immunological intolerance between the mother and the fetus may play an important role in the pathogenesis of preeclampsia. The present case highlights the influence of susceptibility to preeclampsia/hemolysis, elevated liver enzyme levels, and low platelet levels (HELLP) syndrome due to preexisting autoimmune conditions. In vitro fertilization (IVF)Donor embryo pregnancy (DEM) pregnancy is one such unique scenario where there exists partial immunological disparity between the native intrauterine environment and the implanted donor embryo that could predispose to autoimmune problems in pregnancy. This case illustrates a similar scenario in which a pregnant woman with IVF-DEM conception and antinuclear antibody (ANA) positive status manifested with a normotensive partial HELLP syndrome which was reiterated by the fact that there was clinical evidence of retroperitoneal hemorrhage intraoperatively during cesarean along with the neonate who was diagnosed to have L-carnitine deficiency, which is unique to fetuses with mothers of HELLP syndrome.","PeriodicalId":38998,"journal":{"name":"International Journal of Infertility and Fetal Medicine","volume":"8 1","pages":"73-75"},"PeriodicalIF":0.0,"publicationDate":"2016-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90725634","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-08-01DOI: 10.5005/jp-journals-10016-1131
K. Muthukumar, T. Aleyamma, Sumi V Thomas
{"title":"Severe Early-onset Ovarian Hyperstimulation Syndrome following Use of GnRH Agonist Trigger along with Low-dose hCG","authors":"K. Muthukumar, T. Aleyamma, Sumi V Thomas","doi":"10.5005/jp-journals-10016-1131","DOIUrl":"https://doi.org/10.5005/jp-journals-10016-1131","url":null,"abstract":"","PeriodicalId":38998,"journal":{"name":"International Journal of Infertility and Fetal Medicine","volume":"97 1","pages":"68-72"},"PeriodicalIF":0.0,"publicationDate":"2016-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76677403","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-08-01DOI: 10.5005/jp-journals-10016-1125
S. Hemraj, S. M. Abraham, U. Vinayaka, G. Ravichandra, Devdas Acharya
Background: Gestational age estimation is one of the most important information conveyed by a sonologist when performing an obstetric ultrasound examination. The traditional fetal biometric parameters, such as biparietal diameter (BPD), head circumference (HC), femur length (FL), and abdominal circumference become increasingly unreliable for accurate gestational age estimation with advancing pregnancy, especially in 3rd trimester. This study was conducted to assess the role of fetal kidney length (KL) as an alternate parameter to assess gestational age in 2nd and 3rd trimesters. Aim: To assess relationship between sonographic gestational age and fetal KL between 18 and 39 weeks of gestation. Settings and design: Prospective, cross-sectional, single operator study conducted over a period of 1 year in a medical
{"title":"Sonographic Correlation of Gestational Age with Fetal Kidney Length","authors":"S. Hemraj, S. M. Abraham, U. Vinayaka, G. Ravichandra, Devdas Acharya","doi":"10.5005/jp-journals-10016-1125","DOIUrl":"https://doi.org/10.5005/jp-journals-10016-1125","url":null,"abstract":"Background: Gestational age estimation is one of the most important information conveyed by a sonologist when performing an obstetric ultrasound examination. The traditional fetal biometric parameters, such as biparietal diameter (BPD), head circumference (HC), femur length (FL), and abdominal circumference become increasingly unreliable for accurate gestational age estimation with advancing pregnancy, especially in 3rd trimester. This study was conducted to assess the role of fetal kidney length (KL) as an alternate parameter to assess gestational age in 2nd and 3rd trimesters. Aim: To assess relationship between sonographic gestational age and fetal KL between 18 and 39 weeks of gestation. Settings and design: Prospective, cross-sectional, single operator study conducted over a period of 1 year in a medical","PeriodicalId":38998,"journal":{"name":"International Journal of Infertility and Fetal Medicine","volume":"15 1","pages":"37-41"},"PeriodicalIF":0.0,"publicationDate":"2016-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79348054","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-04-01DOI: 10.5005/JP-JOURNALS-10016-1118
R. Chattopadhyay, S. Yasmin, B. Chakravarty, K. Rao
The aim of the present study was to observe the adverse effects of high level of reactive oxygen species (ROS) in idiopathic male infertility and the role of a combined antioxidant therapy for six months to overcome the detrimental effects of ROS. A prospective study including 185 infertile male was conducted at Institute of Reproductive Medicine (IRM) from January 2014 to April 2015. All the major sperm parameters as well as ROS, antioxidant level and the effect of high ROS level were evaluated before and after the therapy. A significant improvement in sperm motility and concentration were observed after 6 months of therapy. Antioxidant level had increased and ROS level had decreased significantly after the antioxidant treatment. Improvement in morphology and leukocyte concentration were observed though not clinically significant. Conclusion: This combined antioxidant therapy may improve sperm quality after continuous 6 months of treatment. However, further study is needed regarding this experiment for validating the trend.
{"title":"Effect of Continuous 6 Months Oral Antioxidant Combination with Universally recommended Dosage in Idiopathic Male Infertility","authors":"R. Chattopadhyay, S. Yasmin, B. Chakravarty, K. Rao","doi":"10.5005/JP-JOURNALS-10016-1118","DOIUrl":"https://doi.org/10.5005/JP-JOURNALS-10016-1118","url":null,"abstract":"The aim of the present study was to observe the adverse effects of high level of reactive oxygen species (ROS) in idiopathic male infertility and the role of a combined antioxidant therapy for six months to overcome the detrimental effects of ROS. A prospective study including 185 infertile male was conducted at Institute of Reproductive Medicine (IRM) from January 2014 to April 2015. All the major sperm parameters as well as ROS, antioxidant level and the effect of high ROS level were evaluated before and after the therapy. A significant improvement in sperm motility and concentration were observed after 6 months of therapy. Antioxidant level had increased and ROS level had decreased significantly after the antioxidant treatment. Improvement in morphology and leukocyte concentration were observed though not clinically significant. Conclusion: This combined antioxidant therapy may improve sperm quality after continuous 6 months of treatment. However, further study is needed regarding this experiment for validating the trend.","PeriodicalId":38998,"journal":{"name":"International Journal of Infertility and Fetal Medicine","volume":"86 1","pages":"0-0"},"PeriodicalIF":0.0,"publicationDate":"2016-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90597766","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-01-01DOI: 10.5005/JP-JOURNALS-10016-1120
Sandya, Pratap Kumar
Background: Endometriosis is one of the most commonly encountered benign problems in gynecology. Ultrasound and endocrine parameters have been widely accepted as markers of ovarian reserve. Anti-Mullerian hormone (AMH) in conjugation with antral follicle counts is now believed to be an excellent measure for detecting ovarian reserve. Surgical approach has a fundamental role in the management of endometriosis. The loss of normal follicles can be studied by histopathological assessment of the cyst wall. The postoperative decline in the ovarian reserve is believed to have a correlation with number of endometriomas and diameter of the cyst wall.Objective: This prospective observational study was undertaken to evaluate the effect of laparoscopic cystectomy with respect to number and size of the cyst on ovarian reserve parameters.Materials and methods: Fifty patients undergoing laparoscopic endometrioma cystectomy were analyzed. Cysts of 5cm and the number of cysts were studied. Statistical analysis was done using Mauchly’s test of sphericity. Anti-Mullerian hormone and antral follicle count were estimated prior to and 1 month after surgery. Pre and postop values were compared and analyzed with respect to number and size of endometrioma.Observation and Results: There was an overall drop of AMH from 3.8 ± 3.01 to 2.67 ± 1.92 ng/ml (p 5 cm cyst (p 5 cm respectively. Histopathological analysis showed loss of follicles in 25% of the cyst walls. This was correlating with the drop in both AMH and AFC postoperatively.Conclusion: Size and number of cyst does affect ovarian reserve to the effect that smaller and bilateral cyst leads to a greater decline in the same.
{"title":"Size of Endometrioma and Number does Influence the Ovarian Reserve: A Prospective Observational Study","authors":"Sandya, Pratap Kumar","doi":"10.5005/JP-JOURNALS-10016-1120","DOIUrl":"https://doi.org/10.5005/JP-JOURNALS-10016-1120","url":null,"abstract":"Background: Endometriosis is one of the most commonly encountered benign problems in gynecology. Ultrasound and endocrine parameters have been widely accepted as markers of ovarian reserve. Anti-Mullerian hormone (AMH) in conjugation with antral follicle counts is now believed to be an excellent measure for detecting ovarian reserve. Surgical approach has a fundamental role in the management of endometriosis. The loss of normal follicles can be studied by histopathological assessment of the cyst wall. The postoperative decline in the ovarian reserve is believed to have a correlation with number of endometriomas and diameter of the cyst wall.Objective: This prospective observational study was undertaken to evaluate the effect of laparoscopic cystectomy with respect to number and size of the cyst on ovarian reserve parameters.Materials and methods: Fifty patients undergoing laparoscopic endometrioma cystectomy were analyzed. Cysts of 5cm and the number of cysts were studied. Statistical analysis was done using Mauchly’s test of sphericity. Anti-Mullerian hormone and antral follicle count were estimated prior to and 1 month after surgery. Pre and postop values were compared and analyzed with respect to number and size of endometrioma.Observation and Results: There was an overall drop of AMH from 3.8 ± 3.01 to 2.67 ± 1.92 ng/ml (p 5 cm cyst (p 5 cm respectively. Histopathological analysis showed loss of follicles in 25% of the cyst walls. This was correlating with the drop in both AMH and AFC postoperatively.Conclusion: Size and number of cyst does affect ovarian reserve to the effect that smaller and bilateral cyst leads to a greater decline in the same.","PeriodicalId":38998,"journal":{"name":"International Journal of Infertility and Fetal Medicine","volume":"6 1","pages":"14-18"},"PeriodicalIF":0.0,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87112209","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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