Pub Date : 2017-01-01DOI: 10.1016/j.eq.2016.09.009
Raúl Garza-Velasco , Jacqueline Ávila-de Jesús , Luis Manuel Perea-Mejía
Understanding of tuberculosis (TB) requires students to identify some critical points. The disease is caused by Mycobacterium tuberculosis, a peculiar bacterium mainly transmitted by inhaling infectious droplets expelled when coughing, talking and sneezing. One of the least understood aspects is that, following the exposure to the infectious droplets, a third of the people develop a latent pulmonary infection. The last means that some people control, rather than eliminate, the bacteria; therefore, some of them can later develop the TB disease, especially when they present an immunological deficiency. The key is to recognize the cell-mediated immunity as a determining factor in the course of the latent or active infection and that the antibodies, the complement system and the phagocytosis by non-activated macrophages result irrelevant in the defense against TB.
Another major concern is the effect of multidrug resistant and extensively drug resistant strains. Management of multidrug resistant -TB and extensively drug resistant -TB is more complicated due the long treatment periods and the elevated costs.
{"title":"Tuberculosis pulmonar: la epidemia mundial continúa y la enseñanza de este tema resulta crucial y compleja","authors":"Raúl Garza-Velasco , Jacqueline Ávila-de Jesús , Luis Manuel Perea-Mejía","doi":"10.1016/j.eq.2016.09.009","DOIUrl":"10.1016/j.eq.2016.09.009","url":null,"abstract":"<div><p>Understanding of tuberculosis (TB) requires students to identify some critical points. The disease is caused by <em>Mycobacterium tuberculosis</em>, a peculiar bacterium mainly transmitted by inhaling infectious droplets expelled when coughing, talking and sneezing. One of the least understood aspects is that, following the exposure to the infectious droplets, a third of the people develop a latent pulmonary infection. The last means that some people control, rather than eliminate, the bacteria; therefore, some of them can later develop the TB disease, especially when they present an immunological deficiency. The key is to recognize the cell-mediated immunity as a determining factor in the course of the latent or active infection and that the antibodies, the complement system and the phagocytosis by non-activated macrophages result irrelevant in the defense against TB.</p><p>Another major concern is the effect of multidrug resistant and extensively drug resistant strains. Management of multidrug resistant -TB and extensively drug resistant -TB is more complicated due the long treatment periods and the elevated costs.</p></div>","PeriodicalId":39011,"journal":{"name":"Educacion Quimica","volume":"28 1","pages":"Pages 38-43"},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.eq.2016.09.009","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132644383","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-01-01DOI: 10.1016/j.eq.2016.06.002
Fernanda Saldívar-González, Fernando D. Prieto-Martínez, José L. Medina-Franco
Drug discovery is a complex and expensive process where different research areas converge. Computational methods have been part of the multidisciplinary efforts and their principles should be included in courses of Medicinal Chemistry. In a given project, the application of computational approaches depends on the information available for the system and the specific goals of the study. Computational approaches have made key contributions to perform efficient analyses of data, filtering compounds collections to select molecules for experimental screening, generate hypothesis to understand the mechanism of action of drugs, and the design of new chemical structures. In addition, computational methods have made significant contributions to develop drugs that are in clinical use. However, there are several challenges to face. Addressing these challenges promote innovation and improvement of methodologies that form part of the multidisciplinary effort to develop drugs.
{"title":"Descubrimiento y desarrollo de fármacos: un enfoque computacional","authors":"Fernanda Saldívar-González, Fernando D. Prieto-Martínez, José L. Medina-Franco","doi":"10.1016/j.eq.2016.06.002","DOIUrl":"10.1016/j.eq.2016.06.002","url":null,"abstract":"<div><p>Drug discovery is a complex and expensive process where different research areas converge. Computational methods have been part of the multidisciplinary efforts and their principles should be included in courses of Medicinal Chemistry. In a given project, the application of computational approaches depends on the information available for the system and the specific goals of the study. Computational approaches have made key contributions to perform efficient analyses of data, filtering compounds collections to select molecules for experimental screening, generate hypothesis to understand the mechanism of action of drugs, and the design of new chemical structures. In addition, computational methods have made significant contributions to develop drugs that are in clinical use. However, there are several challenges to face. Addressing these challenges promote innovation and improvement of methodologies that form part of the multidisciplinary effort to develop drugs.</p></div>","PeriodicalId":39011,"journal":{"name":"Educacion Quimica","volume":"28 1","pages":"Pages 51-58"},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.eq.2016.06.002","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122282116","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-10-01DOI: 10.1016/j.eq.2016.08.001
Ivana Núñez , Marina Míguez , Gustavo Seoane
The use of ICT in education does not imply innovation per se, since these technologies can be used to maintain immutable educational models, and therefore the adequacy and scope of the incorporation must be analyzed. In order to provide elements for the reflection on the possibilities of incorporating tools to support teaching and learning processes, the results from an investigation carried out within the Department of Organic Chemistry of the Faculty of Chemistry, Universidad de la República, are analyzed. This paper discusses the use of wikies as a tool for the Organic Chemistry Laboratory course corresponding to the third year of all careers offered by the Faculty of Chemistry (Universidad de la República) through the students’ reports, the platform registers and the opinions expressed by the course participants.
在教育中使用信通技术本身并不意味着创新,因为这些技术可以用来维持不变的教育模式,因此必须分析这种结合的适当性和范围。为了提供关于整合工具来支持教学和学习过程的可能性的反思元素,分析了在universsidad de la República化学系有机化学系进行的调查结果。本文通过学生的报告、平台注册和课程参与者的意见,讨论了在化学系(universsidad de la República)所有职业所提供的三年级有机化学实验课程中使用wiki作为工具的问题。
{"title":"Wikis en Moodle: la mirada de estudiantes y docentes","authors":"Ivana Núñez , Marina Míguez , Gustavo Seoane","doi":"10.1016/j.eq.2016.08.001","DOIUrl":"https://doi.org/10.1016/j.eq.2016.08.001","url":null,"abstract":"<div><p>The use of ICT in education does not imply innovation per se, since these technologies can be used to maintain immutable educational models, and therefore the adequacy and scope of the incorporation must be analyzed. In order to provide elements for the reflection on the possibilities of incorporating tools to support teaching and learning processes, the results from an investigation carried out within the Department of Organic Chemistry of the Faculty of Chemistry, Universidad de la República, are analyzed. This paper discusses the use of wikies as a tool for the Organic Chemistry Laboratory course corresponding to the third year of all careers offered by the Faculty of Chemistry (Universidad de la República) through the students’ reports, the platform registers and the opinions expressed by the course participants.</p></div>","PeriodicalId":39011,"journal":{"name":"Educacion Quimica","volume":"27 4","pages":"Pages 257-263"},"PeriodicalIF":0.0,"publicationDate":"2016-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.eq.2016.08.001","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91624381","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-10-01DOI: 10.1016/j.eq.2016.07.001
Ronald Márquez, Laura Tolosa, Rubén Gómez, César Izaguirre, Leonardo Rennola, Johnny Bullón, Beatriz Sandia
The teaching-learning process in traditional college education uses strategies that place the student as a recipient of information transmitted by the teacher, which is conceptualized as knowledge. The reality in which we live requires generating training solutions to meet the needs of individuals in the development of skills or know-how to respond to society, to form individuals capable of learning to learn and learning to transfer, prepared to continually seek knowledge and able to create and innovate. In this paper, the results of the implementation of the strategy ‘Reproducing an Innovation Environment in the Classroom’ (RAIS) in courses of the Chemical Engineering curriculum, in Universidad de Los Andes, Mérida-Venezuela are presented. This is a strategy of teaching, learning and assessment in which the student is a co-participant in the construction and generation of knowledge, developing the skills proposed in the course by the execution of a product. RAIS strategy was applied in the courses of Physical Chemistry for Chemical Engineers, Industrial Chemistry I and Laboratory of Industrial Chemistry, where students obtained a finished product using the know-how in the area of each course. This strategy led to an increase in motivation over other courses based on lectures, and the development of the ability to function and find solutions in multidisciplinary groups workplaces. It is important to note that more than 80% of students said the RAIS strategy contributes to their personal development and training for applied research.
{"title":"Reproducción de un ambiente de innovación en el salón de clase. Una estrategia para promover la creatividad en la educación en Ingeniería Química","authors":"Ronald Márquez, Laura Tolosa, Rubén Gómez, César Izaguirre, Leonardo Rennola, Johnny Bullón, Beatriz Sandia","doi":"10.1016/j.eq.2016.07.001","DOIUrl":"https://doi.org/10.1016/j.eq.2016.07.001","url":null,"abstract":"<div><p>The teaching-learning process in traditional college education uses strategies that place the student as a recipient of information transmitted by the teacher, which is conceptualized as knowledge. The reality in which we live requires generating training solutions to meet the needs of individuals in the development of skills or know-how to respond to society, to form individuals capable of learning to learn and learning to transfer, prepared to continually seek knowledge and able to create and innovate. In this paper, the results of the implementation of the strategy ‘Reproducing an Innovation Environment in the Classroom’ (RAIS) in courses of the Chemical Engineering curriculum, in Universidad de Los Andes, Mérida-Venezuela are presented. This is a strategy of teaching, learning and assessment in which the student is a co-participant in the construction and generation of knowledge, developing the skills proposed in the course by the execution of a product. RAIS strategy was applied in the courses of Physical Chemistry for Chemical Engineers, Industrial Chemistry<!--> <!-->I and Laboratory of Industrial Chemistry, where students obtained a finished product using the know-how in the area of each course. This strategy led to an increase in motivation over other courses based on lectures, and the development of the ability to function and find solutions in multidisciplinary groups workplaces. It is important to note that more than 80% of students said the RAIS strategy contributes to their personal development and training for applied research.</p></div>","PeriodicalId":39011,"journal":{"name":"Educacion Quimica","volume":"27 4","pages":"Pages 249-256"},"PeriodicalIF":0.0,"publicationDate":"2016-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.eq.2016.07.001","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91624383","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The radioactivity is more known for adverse effects by the explosion of atomic bombs in World War II, but also has features beneficial to health care since it serves for the early diagnosis of diseases to your treatment. This paper presents, from a perspective of chemical education, the fundamental concepts of the Emission of Positron Tomography (PET). Also explains the process of production of radiopharmaceuticals for PET, in particular 18F. Also, different types of radiopharmaceuticals used for diagnosis of oncological, neurological and cardiac diseases are discussed. The use and clinical applications of this method of Imaging is already a reality in Mexico since 2005. It is expected students and teachers of the area chemical biological sciences achieve a better understanding and an overview of the scope and applications that this technique can have.
{"title":"Producción de radiofármacos para tomografía por emisión de positrones (PET) y su aplicación en el diagnóstico de diversas enfermedades","authors":"Adolfo Obaya Valdivia, Jesús López López, Yolanda Marina Vargas-Rodríguez, Oyuki Camacho González","doi":"10.1016/j.eq.2016.04.005","DOIUrl":"10.1016/j.eq.2016.04.005","url":null,"abstract":"<div><p>The radioactivity is more known for adverse effects by the explosion of atomic bombs in World War II, but also has features beneficial to health care since it serves for the early diagnosis of diseases to your treatment. This paper presents, from a perspective of chemical education, the fundamental concepts of the Emission of Positron Tomography (PET). Also explains the process of production of radiopharmaceuticals for PET, in particular <sup>18</sup>F. Also, different types of radiopharmaceuticals used for diagnosis of oncological, neurological and cardiac diseases are discussed. The use and clinical applications of this method of Imaging is already a reality in Mexico since 2005. It is expected students and teachers of the area chemical biological sciences achieve a better understanding and an overview of the scope and applications that this technique can have.</p></div>","PeriodicalId":39011,"journal":{"name":"Educacion Quimica","volume":"27 4","pages":"Pages 292-299"},"PeriodicalIF":0.0,"publicationDate":"2016-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.eq.2016.04.005","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114941985","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-10-01DOI: 10.1016/j.eq.2015.09.012
Jaime Wisniak
Henry Enfield Roscoe (1833–1915), together with Robert Bunsen, his mentor, carried on fundamental research in photochemistry, determining its laws and quantitative effects. His most important studies were on the chemistry of vanadium, uranium, tungsten, and molybdenum, their oxides and oxychlorides, carrying on, for the first time, their synthesis and separation. He also did important studies on public heath. His academic activities transformed Owens College (Victoria University) into the leading chemistry school in Britain.
{"title":"Henry Enfield Roscoe","authors":"Jaime Wisniak","doi":"10.1016/j.eq.2015.09.012","DOIUrl":"10.1016/j.eq.2015.09.012","url":null,"abstract":"<div><p>Henry Enfield Roscoe (1833–1915), together with Robert Bunsen, his mentor, carried on fundamental research in photochemistry, determining its laws and quantitative effects. His most important studies were on the chemistry of vanadium, uranium, tungsten, and molybdenum, their oxides and oxychlorides, carrying on, for the first time, their synthesis and separation. He also did important studies on public heath. His academic activities transformed Owens College (Victoria University) into the leading chemistry school in Britain.</p></div>","PeriodicalId":39011,"journal":{"name":"Educacion Quimica","volume":"27 4","pages":"Pages 240-248"},"PeriodicalIF":0.0,"publicationDate":"2016-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.eq.2015.09.012","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128687818","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-10-01DOI: 10.1016/j.eq.2016.07.002
Yareli Rojas-Aguirre, Karina Aguado-Castrejón, Israel González-Méndez
The term nanotechnology refers to a number of disciplines intended to study materials and structures at the nanoscale. One of the most important areas of nanotechnology is nanomedicine, which is focused in great extent on the design and development of drug delivery systems. These drug delivery platforms can display very sophisticated properties and unique features, and are considered as the revolution of the conventional chemotherapies, specifically those to treat cancer. In this work we review the concept of nanomedicine and its application on the design of nanocarriers of antineoplastic drugs and highlight some aspects that have to be addressed to translate the drug delivery platforms in to devices with possibilities to reach clinical trials.
{"title":"La nanomedicina y los sistemas de liberación de fármacos: ¿la (r)evolución de la terapia contra el cáncer?","authors":"Yareli Rojas-Aguirre, Karina Aguado-Castrejón, Israel González-Méndez","doi":"10.1016/j.eq.2016.07.002","DOIUrl":"10.1016/j.eq.2016.07.002","url":null,"abstract":"<div><p>The term nanotechnology refers to a number of disciplines intended to study materials and structures at the nanoscale. One of the most important areas of nanotechnology is nanomedicine, which is focused in great extent on the design and development of drug delivery systems. These drug delivery platforms can display very sophisticated properties and unique features, and are considered as the revolution of the conventional chemotherapies, specifically those to treat cancer. In this work we review the concept of nanomedicine and its application on the design of nanocarriers of antineoplastic drugs and highlight some aspects that have to be addressed to translate the drug delivery platforms in to devices with possibilities to reach clinical trials.</p></div>","PeriodicalId":39011,"journal":{"name":"Educacion Quimica","volume":"27 4","pages":"Pages 286-291"},"PeriodicalIF":0.0,"publicationDate":"2016-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.eq.2016.07.002","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125525292","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-10-01DOI: 10.1016/j.eq.2016.09.001
Alberto Vela
A review of the methods developed within Theoretical Chemistry to study matter in many spatial and temporal scales is presented. The scientific career of a well known theoretical chemist is used to show how the astonishing advances that have been achieved in four decades in the development of theories, codes (algorithms) and computer technology allow nowadays the reliable study of the electronic structure of systems whose sizes were unmanageable forty years ago. It is emphasized that the central difficulty in studying Chemistry from a theoretical perspective is that, in every scale, one deals with a many-body problem whose solution and comprehension are still an unsolved and fascinating scientific challenge.
{"title":"Logros y perspectivas de la Química Teórica","authors":"Alberto Vela","doi":"10.1016/j.eq.2016.09.001","DOIUrl":"10.1016/j.eq.2016.09.001","url":null,"abstract":"<div><p>A review of the methods developed within Theoretical Chemistry to study matter in many spatial and temporal scales is presented. The scientific career of a well known theoretical chemist is used to show how the astonishing advances that have been achieved in four decades in the development of theories, codes (algorithms) and computer technology allow nowadays the reliable study of the electronic structure of systems whose sizes were unmanageable forty years ago. It is emphasized that the central difficulty in studying Chemistry from a theoretical perspective is that, in every scale, one deals with a many-body problem whose solution and comprehension are still an unsolved and fascinating scientific challenge.</p></div>","PeriodicalId":39011,"journal":{"name":"Educacion Quimica","volume":"27 4","pages":"Pages 278-285"},"PeriodicalIF":0.0,"publicationDate":"2016-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.eq.2016.09.001","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124405268","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}