Pub Date : 2021-04-21DOI: 10.22038/IJOGI.2021.18177
Nasrin Kheradmand, Z. Nadi, M. Baazm
Introduction: Free radicals play a double role in the body based on their physiological level and can be beneficial or harmful. This review study was performed with aim to evaluate the cellular and molecular mechanisms of oxidative stress on spermatogenesis and oogenesis and the role of using antioxidant in improving fertility in men and women. Methods: In this review study, the issues related to the role of free radicals and antioxidants on male and female fertility disorders were searched in the Persian and English databases including: Elsevier, Scopus, Irandoc, SID, Iran medex, Sciencedirect, Pubmed, GoogleScholar and Web of Science using the keywords of free radicals, male infertility, female infertility, and antioxidants without any time limitation. Finally, 63 studies entered the review study. Results: The excessive production of free radicals in the male reproductive system causes damage to DNA, RNA, and sperm membranes, and ultimately disrupts spermatogenesis. It also causes disorders in the female genital tract including defect in oocyte development and maturation, follicular growth and function of corpus luteum. Conclusion: According the results of previous studies, using antioxidants may remove the harmful effects of free radicals on male and female fertility.
导读:自由基在人体中根据其生理水平起着双重作用，可有益也可有害。本文旨在探讨氧化应激对精子和卵子发生的细胞和分子机制，以及抗氧化剂在提高男性和女性生育能力中的作用。方法:在本综述研究中，以自由基、男性不育、女性不育、抗氧化剂为关键词，无时间限制地检索Elsevier、Scopus、Irandoc、SID、Iran medex、Sciencedirect、Pubmed、GoogleScholar和Web of Science等波斯语和英语数据库中有关自由基和抗氧化剂在男性和女性生育障碍中的作用的相关问题。最终有63项研究进入回顾性研究。结果:男性生殖系统中自由基的过量产生会导致DNA、RNA和精子膜的损伤，最终破坏精子的发生。它还会引起女性生殖道的紊乱，包括卵母细胞发育和成熟、卵泡生长和黄体功能的缺陷。结论:根据以往的研究结果，使用抗氧化剂可以消除自由基对男性和女性生育能力的有害影响。
{"title":"The role of free radicals and antioxidants in male and female fertility disorders: review study","authors":"Nasrin Kheradmand, Z. Nadi, M. Baazm","doi":"10.22038/IJOGI.2021.18177","DOIUrl":"https://doi.org/10.22038/IJOGI.2021.18177","url":null,"abstract":"Introduction: Free radicals play a double role in the body based on their physiological level and can be beneficial or harmful. This review study was performed with aim to evaluate the cellular and molecular mechanisms of oxidative stress on spermatogenesis and oogenesis and the role of using antioxidant in improving fertility in men and women. \u0000Methods: In this review study, the issues related to the role of free radicals and antioxidants on male and female fertility disorders were searched in the Persian and English databases including: Elsevier, Scopus, Irandoc, SID, Iran medex, Sciencedirect, Pubmed, GoogleScholar and Web of Science using the keywords of free radicals, male infertility, female infertility, and antioxidants without any time limitation. Finally, 63 studies entered the review study. \u0000Results: The excessive production of free radicals in the male reproductive system causes damage to DNA, RNA, and sperm membranes, and ultimately disrupts spermatogenesis. It also causes disorders in the female genital tract including defect in oocyte development and maturation, follicular growth and function of corpus luteum. \u0000Conclusion: According the results of previous studies, using antioxidants may remove the harmful effects of free radicals on male and female fertility.","PeriodicalId":39154,"journal":{"name":"Iranian Journal of Obstetrics, Gynecology and Infertility","volume":"54 1","pages":"96-106"},"PeriodicalIF":0.0,"publicationDate":"2021-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85751004","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-03-21DOI: 10.22038/IJOGI.2021.17990
A. A. Jazi, Esmaeil Moradi Sarteshnizi, M. Fathi
ntroduction: Chronic inflammation can be the main cause of many common diseases in old age. Elevated level of CRP and proinflammatory cytokines such as TNF-α is positively associated with fibroblast growth factor 23 (FGF23). Therefore, considering the potentially beneficial effect of elastic band resistance training (EBRT) on these variables, this study was performed with aim to investigate the effect of 12 weeks of selected EBRT on serum levels of FGF23, TNF-α and hsCRP in overweight elderly women. Methods: This clinical trial study was performed in 2017 on 28 elderly women in Shahrekord. The subjects were randomly divided into experimental and control groups. EBRT was performed for 12 weeks. Fasting blood samples were taken 24 hours before the first training session and 48 hours after the last training session to measure serum levels of FGF23, TNF-α and hsCRP. Data were analyzed by SPSS software (version 25) and repeated measure two-way ANOVA test. P<0.05 was considered statistically significant. Results: EBRT had no significant effect on serum FGF23 levels, BMI, and Waist-to-hip ratio in elderly women (P>0.05); but serum levels of TNF-α (P=0.046), hsCRP (P=0.037), and also body fat percentage (P=0.023) significantly decreased after EBRT. Conclusion: Regardless to no significant changes in FGF23 levels, it seems that 12 weeks of EBRT can have a significant effect on reducing chronic inflammation in the elderly by reducing the levels of hsCRP and proinflammatory cytokine TNF-α.
{"title":"Effect of selected elastic band resistance training on serum levels of fibroblast growth factor 23, TNF-α and hsCRP in overweight elderly women","authors":"A. A. Jazi, Esmaeil Moradi Sarteshnizi, M. Fathi","doi":"10.22038/IJOGI.2021.17990","DOIUrl":"https://doi.org/10.22038/IJOGI.2021.17990","url":null,"abstract":"ntroduction: Chronic inflammation can be the main cause of many common diseases in old age. Elevated level of CRP and proinflammatory cytokines such as TNF-α is positively associated with fibroblast growth factor 23 (FGF23). Therefore, considering the potentially beneficial effect of elastic band resistance training (EBRT) on these variables, this study was performed with aim to investigate the effect of 12 weeks of selected EBRT on serum levels of FGF23, TNF-α and hsCRP in overweight elderly women. \u0000Methods: This clinical trial study was performed in 2017 on 28 elderly women in Shahrekord. The subjects were randomly divided into experimental and control groups. EBRT was performed for 12 weeks. Fasting blood samples were taken 24 hours before the first training session and 48 hours after the last training session to measure serum levels of FGF23, TNF-α and hsCRP. Data were analyzed by SPSS software (version 25) and repeated measure two-way ANOVA test. P<0.05 was considered statistically significant. \u0000Results: EBRT had no significant effect on serum FGF23 levels, BMI, and Waist-to-hip ratio in elderly women (P>0.05); but serum levels of TNF-α (P=0.046), hsCRP (P=0.037), and also body fat percentage (P=0.023) significantly decreased after EBRT. \u0000Conclusion: Regardless to no significant changes in FGF23 levels, it seems that 12 weeks of EBRT can have a significant effect on reducing chronic inflammation in the elderly by reducing the levels of hsCRP and proinflammatory cytokine TNF-α.","PeriodicalId":39154,"journal":{"name":"Iranian Journal of Obstetrics, Gynecology and Infertility","volume":"23 1","pages":"26-35"},"PeriodicalIF":0.0,"publicationDate":"2021-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87443771","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-03-21DOI: 10.22038/IJOGI.2021.17996
Mehrnush Mostafaei, Behzad Imani, Shirdel Zandi, S. Rabiei
Introduction: Cesarean section is performed with two technique of closure or non-closure of the peritoneum, but there is disagreement about the advantages and disadvantages of these techniques. Accordingly, this study was performed with aim to compare the early maternal complications of cesarean section in two technique of closure or non-closure of the parietal peritoneum. Methods: This double-blind randomized clinical trial study was performed on 120 patients undergoing cesarean section at Hamadan Fatimah Hospital in 2019. Samples were randomly divided into two groups: closure of the peritoneum (n=60) and non-closure of the peritoneum (n=60). The maternal complications during and after surgery were recorded. Data were analyzed by SPSS software (version 21) and Chi-square, independent t-test and repeated measures. Results: The results showed that operative time and bleeding during surgery were significantly fewer in patients receiving non-closure technique (p 0.05). Conclusion: The complications such as bleeding during surgery, the duration of surgery, ileus after surgery, pain, and consumption of analgesic will occurs with less intensity in patients receiving non-closure technique than patients with closure technique; however, these two methods were not different in terms of surgical wound infection.
{"title":"Early maternal complications of cesarean section in two technique of Closure and non-closure of parietal peritoneum: a double blind randomized clinical trial","authors":"Mehrnush Mostafaei, Behzad Imani, Shirdel Zandi, S. Rabiei","doi":"10.22038/IJOGI.2021.17996","DOIUrl":"https://doi.org/10.22038/IJOGI.2021.17996","url":null,"abstract":"Introduction: Cesarean section is performed with two technique of closure or non-closure of the peritoneum, but there is disagreement about the advantages and disadvantages of these techniques. Accordingly, this study was performed with aim to compare the early maternal complications of cesarean section in two technique of closure or non-closure of the parietal peritoneum. \u0000Methods: This double-blind randomized clinical trial study was performed on 120 patients undergoing cesarean section at Hamadan Fatimah Hospital in 2019. Samples were randomly divided into two groups: closure of the peritoneum (n=60) and non-closure of the peritoneum (n=60). The maternal complications during and after surgery were recorded. Data were analyzed by SPSS software (version 21) and Chi-square, independent t-test and repeated measures. \u0000Results: The results showed that operative time and bleeding during surgery were significantly fewer in patients receiving non-closure technique (p 0.05). \u0000Conclusion: The complications such as bleeding during surgery, the duration of surgery, ileus after surgery, pain, and consumption of analgesic will occurs with less intensity in patients receiving non-closure technique than patients with closure technique; however, these two methods were not different in terms of surgical wound infection.","PeriodicalId":39154,"journal":{"name":"Iranian Journal of Obstetrics, Gynecology and Infertility","volume":"1 1","pages":"77-86"},"PeriodicalIF":0.0,"publicationDate":"2021-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82942472","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-02-19DOI: 10.22038/IJOGI.2021.17822
F. Farzaneh, Ahmad Ahmadian Shalchi, Saeedeh Sarhadi
Introduction: Given the importance of assisted reproductive therapies and achieving a pregnancy leading to live birth, as well as the importance of the used treatments and the various studies which have been performed so far, this study was performed with aim to evaluate the relationship between endometrial pattern and serum progesterone levels at the day before the onset of progesterone suppository in embryo transfer cycles in women referred to Infertility Center of Zahedan. Methods: This cross-sectional study was performed on 50 women who had undergone IVF for any reason and their embryos were frozen in infertility center of Zahedan University of Medical Sciences in 2019. The patients were treated with progesterone suppository 400 mg at morning and 400 mg at evening intra rectally. Demographic data, endometrial pattern and thickness ultrasound, serum progesterone level at the day before the onset of progesterone suppository and serum BHCG levels 14 days after embryo transfer were recorded. Data were analyzed by SPSS statistical software (version 24) and Chi-square and Mann-Whitney tests. P<0.05 was considered statistically significant. Results: IVF outcome was positive in 13 cases (26%). 23 patients (46%) had homogenous endometrial pattern and 27 (54%) had three-line pattern. Serum progesterone level were significantly lower in patients who had positive BHCG than patients who had negative BHCG (p <0.001). Conclusion: Among women undergoing IVF, serum progesterone levels and also endometrial pattern (homogenous or three-line) was different. Serum progesterone level before the onset of treatment was related to the pregnancy outcome (positive or negative), as well as in women with lower progesterone levels in day before the start of progesterone suppositories, treatment with progesterone suppository could lead to better pregnancy outcomes following IVF, which is a novel and important finding.
{"title":"Relationship between serum progesterone levels at the day before progesterone suppository administration and pregnancy rate in embryo transfer cycles","authors":"F. Farzaneh, Ahmad Ahmadian Shalchi, Saeedeh Sarhadi","doi":"10.22038/IJOGI.2021.17822","DOIUrl":"https://doi.org/10.22038/IJOGI.2021.17822","url":null,"abstract":"Introduction: Given the importance of assisted reproductive therapies and achieving a pregnancy leading to live birth, as well as the importance of the used treatments and the various studies which have been performed so far, this study was performed with aim to evaluate the relationship between endometrial pattern and serum progesterone levels at the day before the onset of progesterone suppository in embryo transfer cycles in women referred to Infertility Center of Zahedan. \u0000Methods: This cross-sectional study was performed on 50 women who had undergone IVF for any reason and their embryos were frozen in infertility center of Zahedan University of Medical Sciences in 2019. The patients were treated with progesterone suppository 400 mg at morning and 400 mg at evening intra rectally. Demographic data, endometrial pattern and thickness ultrasound, serum progesterone level at the day before the onset of progesterone suppository and serum BHCG levels 14 days after embryo transfer were recorded. Data were analyzed by SPSS statistical software (version 24) and Chi-square and Mann-Whitney tests. P<0.05 was considered statistically significant. \u0000Results: IVF outcome was positive in 13 cases (26%). 23 patients (46%) had homogenous endometrial pattern and 27 (54%) had three-line pattern. Serum progesterone level were significantly lower in patients who had positive BHCG than patients who had negative BHCG (p <0.001). \u0000Conclusion: Among women undergoing IVF, serum progesterone levels and also endometrial pattern (homogenous or three-line) was different. Serum progesterone level before the onset of treatment was related to the pregnancy outcome (positive or negative), as well as in women with lower progesterone levels in day before the start of progesterone suppositories, treatment with progesterone suppository could lead to better pregnancy outcomes following IVF, which is a novel and important finding.","PeriodicalId":39154,"journal":{"name":"Iranian Journal of Obstetrics, Gynecology and Infertility","volume":"67 1","pages":"6-12"},"PeriodicalIF":0.0,"publicationDate":"2021-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91269405","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-26DOI: 10.22038/IJOGI.2021.51049.4460
F. Veisi, Z. Ghanbari, T. Eftekhar, M. Deldar, Azita Ghanbarpour Shiadeh, M. Shariat
Uterine prolapse has been traditionally treated with vaginal hysterectomy and cuff suspension . Recently there is renewed interest in uterine conservation during prolapse surgeries. Prolapse repair with uterine sparing has benefits as shorten time surgery, lesser bleeding, preserving fertility, less invasion and faster recovery. The purpose of this study was to evaluate the success rate and quality of life in women who have undergone one of three types of uterine sparing prolapse surgery. Methods and MaterialsThis retrospective study was performed in Imam Khomeini Hospital, Tehran University of Medical Sciences. The data of 99 patients with uterine prolapse who underwent one of three types of uterine sparing surgery during three years were reviewed and compared in success rate and quality of life.ResultsThe study was based on patients' data files, physical examination and follow up, until 12 months after surgery. The success rate of sacral hysteropexy was higher than two other groups (94%).The highest recurrence was in sacrospinous, in the Ba point ( -2.06± 506) and C point (-2.1±1.084) . The quality of life in the Manchester and sacral hysteropexy group was similar and higher than sacrospinous group.(P Value≤0.01).Early complications after sacral hysteropexy were ileus and defecatory disorder. ConclusionThree uterine prolapse surgeries had success rate higher than 60%. All three surgical groups had a good quality of life and satisfaction 12 months after procedure. The highest recurrence was in sacrospinous in Ba and C points. Finding mesh complications following surgery requires long-term follow-up.
{"title":"The comparison of success rate and quality of life due to three types of uterine sparing prolapse surgery","authors":"F. Veisi, Z. Ghanbari, T. Eftekhar, M. Deldar, Azita Ghanbarpour Shiadeh, M. Shariat","doi":"10.22038/IJOGI.2021.51049.4460","DOIUrl":"https://doi.org/10.22038/IJOGI.2021.51049.4460","url":null,"abstract":"Uterine prolapse has been traditionally treated with vaginal hysterectomy and cuff suspension . Recently there is renewed interest in uterine conservation during prolapse surgeries. Prolapse repair with uterine sparing has benefits as shorten time surgery, lesser bleeding, preserving fertility, less invasion and faster recovery. The purpose of this study was to evaluate the success rate and quality of life in women who have undergone one of three types of uterine sparing prolapse surgery. Methods and MaterialsThis retrospective study was performed in Imam Khomeini Hospital, Tehran University of Medical Sciences. The data of 99 patients with uterine prolapse who underwent one of three types of uterine sparing surgery during three years were reviewed and compared in success rate and quality of life.ResultsThe study was based on patients' data files, physical examination and follow up, until 12 months after surgery. The success rate of sacral hysteropexy was higher than two other groups (94%).The highest recurrence was in sacrospinous, in the Ba point ( -2.06± 506) and C point (-2.1±1.084) . The quality of life in the Manchester and sacral hysteropexy group was similar and higher than sacrospinous group.(P Value≤0.01).Early complications after sacral hysteropexy were ileus and defecatory disorder. ConclusionThree uterine prolapse surgeries had success rate higher than 60%. All three surgical groups had a good quality of life and satisfaction 12 months after procedure. The highest recurrence was in sacrospinous in Ba and C points. Finding mesh complications following surgery requires long-term follow-up.","PeriodicalId":39154,"journal":{"name":"Iranian Journal of Obstetrics, Gynecology and Infertility","volume":"26 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74573338","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.22038/IJOGI.2021.18567
Masoumeh Abedzadeh-kalahroudi, Z. Karimian, S. Nasiri, Melika Sadat Khorshidifard
Introduction: The current and alarming condition of Covid-19 pandemic may cause stress and anxiety in pregnant women. Due to the high prevalence of the disease in Kashan, this study was performed with aim to determine the anxiety and perceived stress of pregnant women toward Covid-19 and its related factors. Methods: This cross-sectional descriptive study was performed in 2020 on 360 pregnant women by electronic questionnaire in Kashan. Data collection tools were demographic-fertility information questionnaire, the questions related to Covid-19 disease, coronavirus anxiety scale (score range: 0-54) and Cohen perceived stress questionnaire (score range: 0-56). Data were analyzed by SPSS software (version 16) and statistical tests of t-test, ANOVA, linear regression and Pearson correlation coefficient. P <0.05 was considered statistically significant. Results: The total anxiety score of pregnant women in relation to Covid-19 disease was 18.71 ±12.48 and the perceived stress score was 24.57±7.00. Linear regression test showed that person's job, problems during pregnancy, delivery history, family members infection with coronavirus and concern about the consequences of the disease for themselves and the infant were the predictive variables of perceived stress score; and the variables of family members infection with coronavirus, concerns about infection of themselves and the infant, concern about receiving prenatal care, and the presence of problems during pregnancy were the predictors of anxiety scores in pregnant women. Conclusion: The level of anxiety and stress of pregnant women was high during the Covid-19 pandemic and women had many concerns about infecting themselves and the infant or referring to receive prenatal care.
{"title":"Anxiety and perceived stress of pregnant women towards COVID-19 disease and its related factors in Kashan (2020)","authors":"Masoumeh Abedzadeh-kalahroudi, Z. Karimian, S. Nasiri, Melika Sadat Khorshidifard","doi":"10.22038/IJOGI.2021.18567","DOIUrl":"https://doi.org/10.22038/IJOGI.2021.18567","url":null,"abstract":"Introduction: The current and alarming condition of Covid-19 pandemic may cause stress and anxiety in pregnant women. Due to the high prevalence of the disease in Kashan, this study was performed with aim to determine the anxiety and perceived stress of pregnant women toward Covid-19 and its related factors. Methods: This cross-sectional descriptive study was performed in 2020 on 360 pregnant women by electronic questionnaire in Kashan. Data collection tools were demographic-fertility information questionnaire, the questions related to Covid-19 disease, coronavirus anxiety scale (score range: 0-54) and Cohen perceived stress questionnaire (score range: 0-56). Data were analyzed by SPSS software (version 16) and statistical tests of t-test, ANOVA, linear regression and Pearson correlation coefficient. P <0.05 was considered statistically significant. Results: The total anxiety score of pregnant women in relation to Covid-19 disease was 18.71 ±12.48 and the perceived stress score was 24.57±7.00. Linear regression test showed that person's job, problems during pregnancy, delivery history, family members infection with coronavirus and concern about the consequences of the disease for themselves and the infant were the predictive variables of perceived stress score; and the variables of family members infection with coronavirus, concerns about infection of themselves and the infant, concern about receiving prenatal care, and the presence of problems during pregnancy were the predictors of anxiety scores in pregnant women. Conclusion: The level of anxiety and stress of pregnant women was high during the Covid-19 pandemic and women had many concerns about infecting themselves and the infant or referring to receive prenatal care.","PeriodicalId":39154,"journal":{"name":"Iranian Journal of Obstetrics, Gynecology and Infertility","volume":"142 1","pages":"8-18"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77835776","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-12-09DOI: 10.22038/IJOGI.2020.44576.4046
Maryam Donyayi, A. Mansouri, M. Sadeghi, Abed Ebrahimi, Shiva Azizi
AbstractIntroduction: Tubo-ovarian abscess is a final stages in acute pelvic inflammatory disease which may be accurred after uterine manipulation or after surgery and is very rare. Even with the development of antibiotic covering and medical care, mortalities resulted from tubo-oavariane abscess rapture due to septic shock and peritonitis are about 10%. Therefore, early diagnosis and treatment are very important. In this study, a tubo-oavarine abscess fistula to vaginal is reported. Patient Description: the patient is a 44 years old woman who experienced abdominal hysterectomy surgery six months ago and hospitalized for a week due to peritonitis sings but after discharge, she was repeatedly referring because of infectionLeukorrhea and pain. Finally, because of abdominal pain and secretions from the vaginal, she underwent laparoscopy. Tubo-oavariane abscess with fistula to the vagina was observed and the secretions were suctioned and its viscosity was released. Then, ooforectomy and salpingectomy were carried out. Conclusion: about the treatment-resistance Leukorrhea after hysterectomy, tubo-oavarine abscess and frequent infection through fistula should be taken into consideration and diagnosis laparoscopy can be effective to select a suitable treatment. Keywords:Pelvic inflammatory disease, Fistula, Tubo-oavariane abscess
{"title":"Tubo-ovarian Abscess Fistula To Vaginal After Hysterectomy: Case Report","authors":"Maryam Donyayi, A. Mansouri, M. Sadeghi, Abed Ebrahimi, Shiva Azizi","doi":"10.22038/IJOGI.2020.44576.4046","DOIUrl":"https://doi.org/10.22038/IJOGI.2020.44576.4046","url":null,"abstract":"AbstractIntroduction: Tubo-ovarian abscess is a final stages in acute pelvic inflammatory disease which may be accurred after uterine manipulation or after surgery and is very rare. Even with the development of antibiotic covering and medical care, mortalities resulted from tubo-oavariane abscess rapture due to septic shock and peritonitis are about 10%. Therefore, early diagnosis and treatment are very important. In this study, a tubo-oavarine abscess fistula to vaginal is reported. Patient Description: the patient is a 44 years old woman who experienced abdominal hysterectomy surgery six months ago and hospitalized for a week due to peritonitis sings but after discharge, she was repeatedly referring because of infectionLeukorrhea and pain. Finally, because of abdominal pain and secretions from the vaginal, she underwent laparoscopy. Tubo-oavariane abscess with fistula to the vagina was observed and the secretions were suctioned and its viscosity was released. Then, ooforectomy and salpingectomy were carried out. Conclusion: about the treatment-resistance Leukorrhea after hysterectomy, tubo-oavarine abscess and frequent infection through fistula should be taken into consideration and diagnosis laparoscopy can be effective to select a suitable treatment. Keywords:Pelvic inflammatory disease, Fistula, Tubo-oavariane abscess","PeriodicalId":39154,"journal":{"name":"Iranian Journal of Obstetrics, Gynecology and Infertility","volume":"28 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74375127","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-11-21DOI: 10.22038/IJOGI.2020.17369
Alamtaj Samsami, Sara Davoodi, Shaghayegh Moradi Alamdarloo, T. Poordast, Zahra Shiravani, Azade Morshedzadeh
Introduction: Human chorionic gonadotropin for the final maturation of eggs in the In-vitro fertilization cycle was associated with the possibility of a negative effect on endometrial acceptance, fetal quality and ovarian hyper stimulation syndrome. Replacing it with a gonadotropin-releasing hormone agonist to trigger final ovulation is expected to reduce these effects. Therefore, this study was performed with aim to evaluate the outcome of triggering in in vitro fertilization with antagonist protocol by gonadotropin-releasing hormone agonist, human chorionic gonadotropin simultaneously with human gonadotropin-releasing hormone agonist and human chorionic gonadotropin. Methods: In this randomized clinical trial study conducted in 2015 and 2016, women were divided into three random groups after preparing the follicles for triggering and ovum retrieval. One group received 0.2 mg of dipherline, the second group received 10,000 units of human chorionic gonadotropin and the other group received 0.2 mg of dipherline along with 1500 units of human chorionic gonadotropin. The number and quality of eggs and embryos were the outcomes of the study. Data were analyzed by SPSS software (version 17) and Leven tests and one-way analysis of variance. P < 0.05 was considered statistically significant. Results: The number of retrieved oocytes in the group receiving gonadotropin-releasing agonist was significantly higher than the other groups (p = 0.001). More embryos were produced in the gonadotropin-releasing hormone agonist group compared to the other two groups (p = 0.009). However, the number of high quality embryos produced in the groups was similar. Conclusion: The onset of final oocyte maturation with gonadotropin-releasing hormone agonist significantly increases the number of retrieved oocytes and obtained embryos. However, dual stimulation using low-dose human chorionic gonadotropin (IU1500) and gonadotropin-releasing hormone agonist did not alter quality of embryo compared to the standard dose of human chorionic gonadotropin (IU10000).
{"title":"نتایج بارداری بهروش لقاح خارج رحمی در تحریک با آگونیست آزاد کننده گنادوتروپین، گنادوتروپین جفتی انسان و یا گنادوتروپین جفتی انسان به همراه آگونیست آزادکننده گنادوتروپین در زنان نابارور؛ کارآزمایی بالینی تصادفی","authors":"Alamtaj Samsami, Sara Davoodi, Shaghayegh Moradi Alamdarloo, T. Poordast, Zahra Shiravani, Azade Morshedzadeh","doi":"10.22038/IJOGI.2020.17369","DOIUrl":"https://doi.org/10.22038/IJOGI.2020.17369","url":null,"abstract":"Introduction: Human chorionic gonadotropin for the final maturation of eggs in the In-vitro fertilization cycle was associated with the possibility of a negative effect on endometrial acceptance, fetal quality and ovarian hyper stimulation syndrome. Replacing it with a gonadotropin-releasing hormone agonist to trigger final ovulation is expected to reduce these effects. Therefore, this study was performed with aim to evaluate the outcome of triggering in in vitro fertilization with antagonist protocol by gonadotropin-releasing hormone agonist, human chorionic gonadotropin simultaneously with human gonadotropin-releasing hormone agonist and human chorionic gonadotropin. \u0000 Methods: In this randomized clinical trial study conducted in 2015 and 2016, women were divided into three random groups after preparing the follicles for triggering and ovum retrieval. One group received 0.2 mg of dipherline, the second group received 10,000 units of human chorionic gonadotropin and the other group received 0.2 mg of dipherline along with 1500 units of human chorionic gonadotropin. The number and quality of eggs and embryos were the outcomes of the study. Data were analyzed by SPSS software (version 17) and Leven tests and one-way analysis of variance. P < 0.05 was considered statistically significant. \u0000 Results: The number of retrieved oocytes in the group receiving gonadotropin-releasing agonist was significantly higher than the other groups (p = 0.001). More embryos were produced in the gonadotropin-releasing hormone agonist group compared to the other two groups (p = 0.009). However, the number of high quality embryos produced in the groups was similar. \u0000Conclusion: The onset of final oocyte maturation with gonadotropin-releasing hormone agonist significantly increases the number of retrieved oocytes and obtained embryos. However, dual stimulation using low-dose human chorionic gonadotropin (IU1500) and gonadotropin-releasing hormone agonist did not alter quality of embryo compared to the standard dose of human chorionic gonadotropin (IU10000).","PeriodicalId":39154,"journal":{"name":"Iranian Journal of Obstetrics, Gynecology and Infertility","volume":"99 1","pages":"1-7"},"PeriodicalIF":0.0,"publicationDate":"2020-11-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78398496","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-10-01DOI: 10.22038/IJOGI.2020.17286
Marzieh Haghbin, Aliya Tabassum Abbasi, Elham Rafei, A. Kheradmand, F. Javdani, N. Hatami, Parya Afraz, N. Kalani
Introduction: Breast cancer is the most common cancer among women Anxiety can weaken the body's immune system and make them vulnerable to the diseases such as coronavirus disease This study was performed with aim to evaluate the level of anxiety caused by the new coronavirus (Covid-19) in patients with breast cancer during the coronavirus pandemic
{"title":"Anxiety caused by new coronavirus (COVID-19) in breast cancer patients during the coronavirus pandemic","authors":"Marzieh Haghbin, Aliya Tabassum Abbasi, Elham Rafei, A. Kheradmand, F. Javdani, N. Hatami, Parya Afraz, N. Kalani","doi":"10.22038/IJOGI.2020.17286","DOIUrl":"https://doi.org/10.22038/IJOGI.2020.17286","url":null,"abstract":"Introduction: Breast cancer is the most common cancer among women Anxiety can weaken the body's immune system and make them vulnerable to the diseases such as coronavirus disease This study was performed with aim to evaluate the level of anxiety caused by the new coronavirus (Covid-19) in patients with breast cancer during the coronavirus pandemic","PeriodicalId":39154,"journal":{"name":"Iranian Journal of Obstetrics, Gynecology and Infertility","volume":"63 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84728975","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-09-12DOI: 10.22038/IJOGI.2021.18303
مهناز محمددوست, دکتر مهرداد فتحی, دکتر کیوان حجازی
مقدمه: فیبرینوژن یکی از مهمترین عوامل التهابی و شاخص پیشبینی کننده در بیماریهای قلبی - عروقی است. مطالعه حاضر با هدف بررسی تأثیر تمرینات هوازی با شدتهای ثابت و متغیر بر ترکیب بدن و برخی عوامل فیزیولوژیک و انعقادی زنان میانسال دارای اضافه وزن انجام شد. روشکار: این مطالعه کاربردی و بهروش نیمهتجربی در سال 1394 بر روی 30 زن در سه گروه 10 نفره تمرین هوازی با شدت ثابت، شدت متغیر و کنترل در شهرستان بجنورد انجام شد. برنامه تمرین هوازی شامل 8 هفته تمرین هوازی، 30 دقیقه فعالیت هوازی با شدت ثابت معادل 60% ضربان قلب و با شدت متغیر شامل 2 دقیقه رکاب زدن با شدت 50% حداکثر ضربان قلب و 1 دقیقه رکاب زدن با شدت 70% حداکثر ضربان قلب بود. سطوح فیبرینوژن، PT، PTT، تعداد پلاکتها و فاکتور غیرانعقادی در 24 ساعت قبل و 48 ساعت بعد از جلسه تمرین جمعآوری شد. تجزیه و تحلیل دادهها با استفاده از نرمافزار آماری SPSS (نسخه 25) و آزمونهای تی همبسته، تحلیل آنالیز کواریانس (ANCOVA) و آزمون تعقیبی توکی بهترتیب برای تغییرات درونگروهی و بینگروهی انجام شد. میزان p کمتر از 05/0 معنیدار در نظر گرفته شد. یافتهها: وزن (شدت ثابت 001/0=p و شدت متغیر 001/0=p)، شاخص توده بدنی (شدت ثابت 001/0=p و شدت متغیر 001/0=p)، فشارخون سیستولی (شدت ثابت 03/0=p و شدت متغیر 001/0=p) و فشارخون دیاستولی (شدت ثابت 001/0=p و شدت متغیر 001/0=p) کاهش معنیداری یافت؛ درصورتیکه درصد چربی بدن فقط در گروه تمرین هوازی با شدت ثابت کاهش معنیداری یافت (001/=p). زمان پروترومبین (شدت ثابت 004/0=p و شدت متغیر 009/0=p)، زمان نسبی ترومبوپلاستین (شدت ثابت 005/0=p و شدت متغیر 01/0=p)، فیبرینوژن (شدت ثابت 001/0=p و شدت متغیر 02/0=p) و تعداد پلاکتها (شدت ثابت 02/0=p و شدت متغیر 001/0=p)، کاهش معنیداری یافت؛ درصورتیکه فاکتور غیرانعقادی در هر دو گروه تمرین هوازی با شدت ثابت و متغیر افزایش معنیداری یافت (شدت ثابت 003/0=p و شدت متغیر 001/0=p). میزان انعطافپذیری (شدت ثابت 003/0=p و شدت متغیر 001/0=p) و حداکثر اکسیژن مصرفی (شدت ثابت 001/0=p و شدت متغیر 001/0=p) در هر دو گروه تمرین هوازی با شدت ثابت و متغیر افزایش معنیداری یافت. نتیجهگیری: 8 هفته تمرین هوازی با دو شدت ثابت و متغیر از طریق کاهش شاخصهای ترکیب بدن، فاکتورهای انعقادی و افزایش شاخصهای آمادگی جسمانی در زنان دارای اضافه وزن میتواند احتمالا در بهبود سلامت قلب و عروق و کاهش التهاب مؤثر باشد.
{"title":"تأثیر تمرینات هوازی با شدت های ثابت و متغیر بر ترکیب بدن، برخی از عوامل فیزیولوژیک و انعقادی زنان میانسال دارای اضافه وزن","authors":"مهناز محمددوست, دکتر مهرداد فتحی, دکتر کیوان حجازی","doi":"10.22038/IJOGI.2021.18303","DOIUrl":"https://doi.org/10.22038/IJOGI.2021.18303","url":null,"abstract":"مقدمه: فیبرینوژن یکی از مهمترین عوامل التهابی و شاخص پیشبینی کننده در بیماریهای قلبی - عروقی است. مطالعه حاضر با هدف بررسی تأثیر تمرینات هوازی با شدتهای ثابت و متغیر بر ترکیب بدن و برخی عوامل فیزیولوژیک و انعقادی زنان میانسال دارای اضافه وزن انجام شد. \u0000روشکار: این مطالعه کاربردی و بهروش نیمهتجربی در سال 1394 بر روی 30 زن در سه گروه 10 نفره تمرین هوازی با شدت ثابت، شدت متغیر و کنترل در شهرستان بجنورد انجام شد. برنامه تمرین هوازی شامل 8 هفته تمرین هوازی، 30 دقیقه فعالیت هوازی با شدت ثابت معادل 60% ضربان قلب و با شدت متغیر شامل 2 دقیقه رکاب زدن با شدت 50% حداکثر ضربان قلب و 1 دقیقه رکاب زدن با شدت 70% حداکثر ضربان قلب بود. سطوح فیبرینوژن، PT، PTT، تعداد پلاکتها و فاکتور غیرانعقادی در 24 ساعت قبل و 48 ساعت بعد از جلسه تمرین جمعآوری شد. تجزیه و تحلیل دادهها با استفاده از نرمافزار آماری SPSS (نسخه 25) و آزمونهای تی همبسته، تحلیل آنالیز کواریانس (ANCOVA) و آزمون تعقیبی توکی بهترتیب برای تغییرات درونگروهی و بینگروهی انجام شد. میزان p کمتر از 05/0 معنیدار در نظر گرفته شد. \u0000یافتهها: وزن (شدت ثابت 001/0=p و شدت متغیر 001/0=p)، شاخص توده بدنی (شدت ثابت 001/0=p و شدت متغیر 001/0=p)، فشارخون سیستولی (شدت ثابت 03/0=p و شدت متغیر 001/0=p) و فشارخون دیاستولی (شدت ثابت 001/0=p و شدت متغیر 001/0=p) کاهش معنیداری یافت؛ درصورتیکه درصد چربی بدن فقط در گروه تمرین هوازی با شدت ثابت کاهش معنیداری یافت (001/=p). زمان پروترومبین (شدت ثابت 004/0=p و شدت متغیر 009/0=p)، زمان نسبی ترومبوپلاستین (شدت ثابت 005/0=p و شدت متغیر 01/0=p)، فیبرینوژن (شدت ثابت 001/0=p و شدت متغیر 02/0=p) و تعداد پلاکتها (شدت ثابت 02/0=p و شدت متغیر 001/0=p)، کاهش معنیداری یافت؛ درصورتیکه فاکتور غیرانعقادی در هر دو گروه تمرین هوازی با شدت ثابت و متغیر افزایش معنیداری یافت (شدت ثابت 003/0=p و شدت متغیر 001/0=p). میزان انعطافپذیری (شدت ثابت 003/0=p و شدت متغیر 001/0=p) و حداکثر اکسیژن مصرفی (شدت ثابت 001/0=p و شدت متغیر 001/0=p) در هر دو گروه تمرین هوازی با شدت ثابت و متغیر افزایش معنیداری یافت. \u0000نتیجهگیری: 8 هفته تمرین هوازی با دو شدت ثابت و متغیر از طریق کاهش شاخصهای ترکیب بدن، فاکتورهای انعقادی و افزایش شاخصهای آمادگی جسمانی در زنان دارای اضافه وزن میتواند احتمالا در بهبود سلامت قلب و عروق و کاهش التهاب مؤثر باشد.","PeriodicalId":39154,"journal":{"name":"Iranian Journal of Obstetrics, Gynecology and Infertility","volume":"130 1","pages":"51-61"},"PeriodicalIF":0.0,"publicationDate":"2020-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89203588","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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