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Prioritizing public health responses in Nigerian drug control policy 在尼日利亚药物管制政策中优先考虑公共卫生对策
Q4 Medicine Pub Date : 2017-01-01 DOI: 10.4314/AJDAS.V16I1
Ediomo-ubong E. Nelson, I. Obot, O. Umoh
Nigeria’s drug control policy, a throwback to colonial dangerous drugs control legislations, is remarkable for its reliance on severe sanctions to curb drug offences. The establishment of the National Drug Law Enforcement Agency (NDLEA) in 1990 took drug control in Nigeria to a crescendo. The agency amalgamates the functions of supply control and demand reduction in a highly-centralized bureaucracy. Although it has been successful in the seizure of drugs and arrest and punishment of offenders, its impact on drug use and related problems is negligible. the success is tainted by rampant corruption and the cost of law enforcement. The development of a comprehensive drug policy which prioritizes demand reduction through public health measures such as prevention and treatment is hampered by the bureaucracy of drug law enforcement, whose direction cannot be changed without altering the structure of the organization. The devolution of functions through the creation of a new agency on drug demand reduction is a step in the right direction. Keywords: drugs, policy, public health, law enforcement, Nigeria
尼日利亚的毒品管制政策是对殖民时期危险毒品管制立法的一种倒退,以依赖严厉制裁来遏制毒品犯罪而闻名。1990年国家禁毒执法机构的成立使尼日利亚的毒品管制达到高潮。该机构在一个高度集中的官僚机构中合并了控制供应和减少需求的职能。虽然它在缉获毒品和逮捕和惩罚罪犯方面取得了成功,但它对吸毒和有关问题的影响微不足道。这种成功受到猖獗的腐败和执法成本的影响。通过预防和治疗等公共卫生措施优先减少需求的全面毒品政策的制定受到了禁毒执法官僚主义的阻碍,不改变该组织的结构就无法改变其方向。通过设立一个减少毒品需求的新机构来下放职能是朝着正确方向迈出的一步。关键词:毒品,政策,公共卫生,执法,尼日利亚
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引用次数: 3
Prior substance use, depression and gender as determinants of self-harm urges in prison inmates: A study of Uyo Prison 先前物质使用、抑郁和性别是监狱囚犯自残冲动的决定因素:尤尤监狱的一项研究
Q4 Medicine Pub Date : 2016-01-01 DOI: 10.4314/AJDAS.V15I1
Mfon E. Ineme, H. Osinowo
This study examined prior substance use, depression and gender as determinants of selfharm urges in prison inmates. It was a survey utilizing ex-post facto design. A total of 183 male and 29 female inmates from Uyo prison participated in the study. Their mean age was 34.4years. Multi-stage sampling method was used. The t-test results {t (210)=2.89, p<.01} showed that inmates who used psychoactive substances before imprisonment reported higher self-harm urges than those who did not use. Also, inmates with high depressive symptoms reported higher self-harm urges than those with low depressive symptoms {t (210)= 4.21, p<.01}. The interaction of prior substance use and depression was significant, Wilks Lambda = .72, F (1, 210) = 19.02, p = <.01, partial eta squared = .17. A post-hoc test was conducted using LSD to show multiple comparison effect. Furthermore, the t-test results {t (210)= 2.60, p<.01} showed that female inmates reported higher self-harm urges than their male counterparts. The findings of this study have implications on the involvement of psychologists and other mental experts in the management of the prison system. Keywords: Self-harm urges, prior substance use, depression, gender, prison inmates
本研究调查了监狱囚犯的药物使用、抑郁和性别作为自残冲动的决定因素。这是一项利用事后设计的调查。共有183名来自Uyo监狱的男囚犯和29名女囚犯参加了这项研究。平均年龄34.4岁。采用多阶段抽样方法。t检验结果{t (210)=2.89, p<。研究表明,在入狱前使用精神活性物质的囚犯比没有使用的人有更高的自残冲动。此外,高抑郁症状的囚犯比低抑郁症状的囚犯报告了更高的自残冲动{t (210)= 4.21, p< 0.01}。既往物质使用与抑郁的交互作用显著,Wilks Lambda = 0.72, F (1,210) = 19.02, p = <。1,偏平方=。17。使用LSD进行事后检验,显示多重比较效应。t检验结果{t (210)= 2.60, p<。显示女囚犯比男囚犯有更高的自残冲动。这项研究的结果对心理学家和其他心理专家参与监狱系统的管理具有启示意义。关键词:自残冲动,既往药物使用,抑郁,性别,监狱囚犯
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引用次数: 2
Drug interaction s in the constituents of street drug mixture“Nyaope”in South Africa: a mini-review 南非街头毒品混合物“Nyaope”成分中的药物相互作用:一个小型综述
Q4 Medicine Pub Date : 2016-01-01 DOI: 10.4314/AJDAS.V15I2
A. Khine, Kedibone Elizabeth Mokwena
Nyaope is a unique South African street drug mixture thought to contain illicit drugs and other compounds and is usually inhaled after wrapping in the Cannabis leaf. Despite its illegalization in March 2014, abuse of Nyaope is on the increase. While highly addictive, withdrawal symptoms are very severe, unbearable and drive the user to desperately seek for the next fix. Due to the lack of knowledge in its composition and how the constituents interact with each other, treatment for withdrawal symptoms and rehabilitation has been a challenge. A mini-literature review was done to explore how the major constituents of Nyaope relate to each other in their actions and in their path of breaking down (metabolism). The literature suggests that the inside opiate group, in between opiates and benzodiazepines, in between opiates and cannabis group, in between benzodiazepines and phenobarbitals, and also amongst the minor constituents, there are extensively shared the metabolic pathways which lead to longer plasma half-life in each of these drugs and thus synergistic effects. These shared pathways are via the cytochrome P450 family of enzymes in the liver cell cytoplasm and these enzyme actions are to inactivate or detoxify the drugs or convert them to more water soluble compounds in order to excrete them through the kidneys. Not only sharing the metabolic pathways, but also the actions of these drugs at certain receptors in the brain have either opposing or stimulating effects on one another, making the complex nature of their combined actions. Such findings can explain the unique withdrawal symptom complex of Nyaope, which is important for the clinicians and public health workers who are dealing with the users. Understanding the biochemical  and metabolic basis of Nyaope drug interactions provides valuable insight towards the development of withdrawal signs and symptoms which may contribute to the targeted treatment program. Keywords: Nyaope, drugs of abuse, withdrawal symptoms, drug synergy, metabolism
Nyaope是一种独特的南非街头毒品混合物,被认为含有非法药物和其他化合物,通常在大麻叶包裹后吸入。尽管它在2014年3月被定为非法,但对Nyaope的滥用仍在增加。虽然高度上瘾,但戒断症状非常严重,难以忍受,并驱使使用者拼命寻找下一个解决方案。由于缺乏对其组成和成分如何相互作用的了解,戒断症状的治疗和康复一直是一个挑战。我们进行了一项小型文献综述,以探索Nyaope的主要成分在其作用和分解(代谢)过程中如何相互关联。文献表明,在阿片类药物内部,在阿片类药物和苯二氮卓类药物之间,在阿片类药物和大麻组之间,在苯二氮卓类药物和苯巴比托类药物之间,以及在次要成分之间,存在广泛共享的代谢途径,导致每种药物的血浆半衰期更长,从而产生协同作用。这些共同的途径是通过肝细胞质中的细胞色素P450酶家族这些酶的作用是使药物失活或解毒或将其转化为更易溶于水的化合物以便通过肾脏排出。不仅共享代谢途径,而且这些药物对大脑中某些受体的作用也会相互对立或刺激,这使得它们的联合作用具有复杂性。这些发现可以解释Nyaope独特的戒断症状复合物,这对与使用者打交道的临床医生和公共卫生工作者很重要。了解Nyaope药物相互作用的生化和代谢基础,为戒断体征和症状的发展提供了有价值的见解,这可能有助于有针对性的治疗方案。关键词:Nyaope,滥用药物,戒断症状,药物协同作用,代谢
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引用次数: 11
Substance abuse and adherence to antiretroviral therapy among patients attending clinic at a specialist hospital in Jos, Nigeria 尼日利亚乔斯一家专科医院门诊病人的药物滥用和抗逆转录病毒治疗依从性
Q4 Medicine Pub Date : 2015-01-01 DOI: 10.4314/AJDAS.V14I1
S. Goar, M. Audu, M. Agbir, B. Matawal
Substance abuse does not only increase susceptibility to HIV/AIDS through high risk Sexual behaviors but it also hastens the progression of the disease among infected persons than in those who do not abuse drugs. Furthermore, drug use impairs adherence to antiretroviral therapy (ART) leading to reduction in ART effectiveness and ultimately increased HIV-related mortality. In North Central Nigeria there is a dearth of information concerning the influence of substance abuse on adherence to ART which has substantially altered the fate of HIV-infected people. The objectives of this study therefore, were to determine the type of substances abused by HIV-infected patients attending clinic at Plateau State Specialists Hospital (PSSH) and to determine the effect of substance abuse and sociodemographic factors on adherence to ART among these patients. Ethical approval was obtained before the commencement of the study which was crosssectional in design. The study was carried out at the infectious disease unit of the Plateau State Specialists Hospital, Jos among 160 consecutive patients. The Alcohol, Smoking and Substance Involvement Screening Test (ASSIST) was used for the assessment of the types of substance abused and AIDS Clinical Trials Group(ACTG) adherence instrument was used to assess reasons for non- adherence. The results showed that 61.9% of the patients did not use any substance of abuse, 38.1% either abused one substance or a combination of substances. Substance abuse were ( p = 0.0001), alcohol abuse (p = 0.003) and educational status ( p = 0.0001) significantly associated with non-adherence to ART while, age ( p = 0.954), employment status ( p = 0.924) and marital status ( p = 0.466) were not. However, logistic regression revealed that only alcohol abuse (B = -1.383, df = 1, p  = .002) predicted non adherence to ART. We recommend the screening of patients on ART for substance abuse and a multi-disciplinary approach to the treatment of HIV/AIDS. Keywords: HIV, substance abuse, medication adherence
药物滥用不仅通过高风险的性行为增加对艾滋病毒/艾滋病的易感性,而且与不滥用药物的人相比,它还加速了感染者的疾病进展。此外,药物使用损害抗逆转录病毒治疗(ART)的依从性,导致抗逆转录病毒治疗有效性降低,并最终增加艾滋病毒相关死亡率。在尼日利亚中北部,缺乏关于药物滥用对坚持抗逆转录病毒治疗的影响的信息,这种影响大大改变了艾滋病毒感染者的命运。因此,本研究的目的是确定在高原州专科医院(PSSH)就诊的艾滋病毒感染患者滥用药物的类型,并确定药物滥用和社会人口因素对这些患者坚持抗逆转录病毒治疗的影响。在横断面设计的研究开始前获得了伦理批准。这项研究是在乔斯高原州立专科医院传染病科对160名连续患者进行的。使用酒精、吸烟和物质介入筛选试验(ASSIST)来评估药物滥用的类型,使用艾滋病临床试验组(ACTG)依从性工具来评估不依从性的原因。结果显示,61.9%的患者不滥用任何一种药物,38.1%的患者滥用一种或多种药物。药物滥用(p = 0.0001)、酒精滥用(p = 0.003)和教育状况(p = 0.0001)与不遵守抗逆转录病毒治疗相关,而年龄(p = 0.954)、就业状况(p = 0.924)和婚姻状况(p = 0.466)与不遵守抗逆转录病毒治疗无关。然而,逻辑回归显示,只有酒精滥用(B = -1.383, df = 1, p = .002)预测不坚持抗逆转录病毒治疗。我们建议对接受抗逆转录病毒治疗的患者进行药物滥用筛查,并采用多学科方法治疗艾滋病毒/艾滋病。关键词:HIV,药物滥用,药物依从性
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引用次数: 3
A qualitative study of alcohol risk perceptions among drinkers in Benue State, Nigeria 尼日利亚贝努埃州饮酒者对酒精风险认知的定性研究
Q4 Medicine Pub Date : 2015-01-01 DOI: 10.4314/AJDAS.V14I2
J. Gire, Alex I. Shaahu
There is evidence in the scientific literature linking alcohol-related deaths and morbidities with excessive alcohol consumption, yet individuals are often undeterred by their experiences of negative alcohol-related outcomes. In seeking to understand this behavior, this exploratory qualitative study was undertaken among Benue State civil servants in Makurdi, Nigeria to explore their reasons for drinking, perception of alcohol risk and, how these shape their alcohol consumption behaviors. Utilizing a purposive and network/snowball sampling technique, twenty-nine self administered open ended questionnaires were administered and analyzed. Findings indicated that drinking was primarily undertaken for enhancement and coping motives. Also, drinkers had knowledge of, and had experienced some alcohol-related dangers such as fights, rape, injury, and driving under the influence of alcohol. However, their drinking motives were valued over and above these experiences of negative alcohol effects, thereby minimizing the perception of personal susceptibility to alcohol related risk. Problem drinking status, the availability of alternative substitutes to drinking and, drinking motives together determine alcohol risk perceptions and drinking behavior. Therefore, in order to fully understand drinking behavior, the influences of drinking motives, personal experiences, drinking status, availability of alcohol substitutes and, risk perceptions should be considered. Keywords: Alcohol risk perceptions, drinking motives, and hazardous drinking
科学文献中有证据表明,酒精相关的死亡和发病率与过度饮酒有关,但个人往往不会被酒精相关的负面结果所吓倒。为了了解这种行为,在尼日利亚马库尔迪的贝努埃州公务员中进行了这项探索性质的研究,以探讨他们饮酒的原因、对酒精风险的认识以及这些因素如何影响他们的酒精消费行为。利用有目的和网络/雪球抽样技术,29份自我管理的开放式问卷被管理和分析。研究结果表明,饮酒主要是为了增强和应对动机。此外,饮酒者了解并经历过一些与酒精有关的危险,如打架、强奸、受伤和在酒精影响下驾驶。然而,他们的饮酒动机比这些负面酒精影响的经历更重要,从而最大限度地减少了个人对酒精相关风险的易感性。饮酒的问题状况、是否有可替代饮酒的替代品以及饮酒动机共同决定了饮酒风险认知和饮酒行为。因此,为了充分了解饮酒行为,应考虑饮酒动机、个人经历、饮酒状况、酒精替代品的可得性和风险认知等因素的影响。关键词:酒精风险认知、饮酒动机和危险饮酒
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引用次数: 3
Monitoring Outdoor Alcohol Advertising in Developing Countries: Findings of a Pilot Study in Five African Countries 监测发展中国家的户外酒类广告:在五个非洲国家进行的试点研究的结果
Q4 Medicine Pub Date : 2014-08-25 DOI: 10.4314/AJDAS.V13I1.13-29
A. D. Bruijin, C. Ferreira-Borges, R. Engels, M. Bhavsar
This paper aims to describe alcohol advertising in the public arena of Gambia, Ghana, Madagascar, Nigeria and  Uganda. Analyses on the placement, channels, size and content of outdoor alcohol advertising practices (N=807) in relation to existing regulations are given. For example, in Gambia, the country with the most stringent alcohol  marketing regulations of all countries studied, outdoor alcohol advertisements are on average smaller and less  attractive to youth; whereas, in Uganda and Ghana, countries with selfregulation, there is limited protection. Findings illustrate the innovative ways in which the alcohol industry attempts to reach their market despite existing alcohol marketing regulations and cultural boundaries. Legal measures could be a policy instrument to protect against  harmful exposure. Key Words : alcohol marketing, outdoor advertising, Africa, alcohol policy
本文旨在描述在冈比亚,加纳,马达加斯加,尼日利亚和乌干达的公共场所酒精广告。分析了户外酒类广告的位置、渠道、规模和内容(N=807)与现行法规的关系。例如,冈比亚是所研究的所有国家中酒类营销条例最严格的国家,该国的户外酒类广告平均规模较小,对年轻人的吸引力较低;而在乌干达和加纳这些实行自我监管的国家,保护措施有限。研究结果表明,尽管现有的酒精营销法规和文化界限,酒精行业仍试图以创新的方式进入市场。法律措施可以成为防止有害暴露的政策工具。关键词:酒类营销;户外广告;非洲
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引用次数: 24
Drinking, Violence Against Women and the Reproduction of Masculinity in Oron, Nigeria 尼日利亚奥伦的饮酒、对妇女的暴力和男性的繁衍
Q4 Medicine Pub Date : 2014-08-25 DOI: 10.4314/AJDAS.V13I1.55-68
E. Ediomo-ubong
Violence against women is recognized as a violation of human rights and a threat to the achievement of gender  equality and development globally. Following suggested link between alcohol use and violence in previous studies,  this study investigates the role of alcohol use and violence in the reproduction of masculinity. Qualitative data from in-depth individual and group interviews with 413 men in 6 villages in Oron, Akwa Ibom State of Nigeria was used.  The data reveals that men use violence in various ways towards their spouses to curb attempts to spurn traditional gender roles. Underlying most of the incidences of male violence is heavy use of alcohol, which is a potent cultural symbol of masculinity. Heavy drinking is common in these communities and its role in the incidence of violence against women is established by the accounts of participants. The rationalization of male violence with reference to the use of alcohol makes it clear that both practices are mutually implicated in the reproduction of local images of masculinity. Policy on alcohol problems and gender-based violence needs to recognize the metonymic significance of drinking and violence in the definition of manhood. Key Words : Alcohol; Masculinity; Violence against Women; Nigeria
对妇女的暴力行为被认为是对人权的侵犯,是对实现全球性别平等和发展的威胁。在之前的研究中,酒精使用和暴力之间存在联系,本研究调查了酒精使用和暴力在男性气概繁殖中的作用。定性数据来自对尼日利亚阿夸伊博姆州奥伦6个村庄的413名男子进行的深入个人和小组访谈。数据显示,男性以各种方式对配偶使用暴力,以抑制对传统性别角色的抛弃。大多数男性暴力事件的根本原因是酗酒,而酗酒是男子气概的有力文化象征。酗酒在这些社区很常见,参与者的叙述证实了酗酒在暴力侵害妇女事件中的作用。将使用酒精的男性暴力合理化表明,这两种做法与当地男子气概形象的再现是相互牵连的。关于酒精问题和基于性别的暴力的政策需要认识到饮酒和暴力在男子气概定义中的转喻意义。关键词:酒精;男子气概;对妇女的暴力行为;尼日利亚
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引用次数: 8
Drug Use Patterns and Socio-Demographic Profiles of Substance Users: Findings from a Substance Abuse Treatment Programme in Gaborone, Botswana 药物使用模式和物质使用者的社会人口特征:来自博茨瓦纳哈博罗内药物滥用治疗方案的调查结果
Q4 Medicine Pub Date : 2014-08-25 DOI: 10.4314/AJDAS.V13I1.43-53
M. Selemogwe, S. Mphele, Kegomoditswe Manyanda
Substance abuse is a critical problem in Botswana, yet empirical evidence on substance users is limited. The current study sought to examine patterns of drug use and sociodemographic profiles of clients who sought treatment at a substance abuse treatment centre in Gaborone, Botswana. Findings showed clients’ age ranged from 13-64 years with a mean age of 28.55 years and SD ±12.59 years. More than half of the clients reported use of legal drugs (76.9%, n=307) and alcohol was the most frequently reported drug (n= 236, 59.1%). In contrast, slightly more than  half of the clients reported use of illegal drugs (53.1 %, n=212) with marijuana being the most prevalent reported illicit drug (74%, n=104). Chi-square analysis also showed differences in use of illegal drugs as a function of clients’ gender (χ2 (1) =13.51, p ˂001) and as a function of the clients’ age (χ2 (4) = 64.04, p˂ .000). The findings of the current study have implications for the formulation of efficient substance abuse policy and interventions and as such recommendations are provided. Key Words : Substance abuse treatment, drug use, illicit drugs, Botswana, sociodemographic variables
药物滥用是博茨瓦纳的一个严重问题,但关于药物使用者的经验证据有限。目前的研究试图检查在博茨瓦纳哈博罗内的药物滥用治疗中心寻求治疗的客户的药物使用模式和社会人口统计资料。患者年龄13-64岁,平均年龄28.55岁,SD±12.59岁。一半以上的客户报告使用合法药物(76.9%,n=307),酒精是最常报告的药物(n= 236, 59.1%)。相比之下,略多于一半的客户报告使用非法药物(53.1%,n=212),大麻是最普遍的报告非法药物(74%,n=104)。卡方分析还显示,非法药物使用的差异是客户性别的函数(χ2 (1) =13.51, p小于001)和客户年龄的函数(χ2 (4) = 64.04, p小于0.001)。目前的研究结果对制定有效的药物滥用政策和干预措施具有影响,因此提出了建议。关键词:药物滥用治疗,药物使用,非法药物,博茨瓦纳,社会人口变量
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引用次数: 4
Self- and collateral spouse-reported alcohol use in Malawi; exploring social drinking norms' potential for alcohol prevention 马拉维自我和附带配偶报告的酒精使用情况;探索社会饮酒规范对酒精预防的潜力
Q4 Medicine Pub Date : 2014-08-25 DOI: 10.4314/AJDAS.V13I1.1-11
H. Natvig, A. Eide, Matilda Hultberg Døving, Annika Linge Hessen, Erik Hoel, J. Ndawala, Gloria Azalde, S. H. Braathen, A. Munthali
Adult (18+ years old) Malawian men and women’s alcohol use and social drinking norms were examined. From  31,676 screened households, heads and spouses in 1,795 households with at least one alcohol user were  interviewed. Alcohol use last 12 months was reported by 27.3% and 1.6% of all adult men and women respectively. Male and female alcohol users’ mean consumption was 8.05 litres and 1.51 litres of pure alcohol respectively. Spouses reported 55 and 61% higher consumption level for their spouses compared to self-reports. Without  including non-drinkers, drinking norms explained 6.7% of men’s and 20.9% of women’s alcohol consumption. Prevention efforts could be directed at helping women not to start drinking by supporting their existing  genderspecific descriptive drinking norms. Key Words : Alcohol, same-sex descriptive norms, household survey, Malawi
调查了马拉维成年(18岁以上)男性和女性的酒精使用情况和社会饮酒规范。在31676个被筛选的家庭中,对1795个至少有一名酒精使用者的家庭的户主和配偶进行了访谈。据报告,在过去12个月中,27.3%的成年男性和1.6%的成年女性饮酒。男性和女性饮酒者的平均纯酒精消费量分别为8.05升和1.51升。与自我报告相比,配偶报告的消费水平分别高出55%和61%。在不包括不饮酒者的情况下,饮酒规范解释了6.7%的男性和20.9%的女性饮酒。预防工作可以通过支持现有的针对特定性别的描述性饮酒规范来帮助妇女不要开始饮酒。关键词:酒精,同性描述性规范,入户调查,马拉维
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引用次数: 3
Self-control and alcohol consumption among university students in Botswana 博茨瓦纳大学生的自我控制与酒精消费
Q4 Medicine Pub Date : 2014-01-01 DOI: 10.4314/AJDAS.V13I2
G. Morutwa, I. Plattner
The study explored the relationship between self-control and alcohol consumption among students at the University of Botswana, and was entrenched within the socialcognitive theory of self-regulation. Data were collected from 135 undergraduate students (42.2% female, 57.8% male) with a mean age of 21.22 years (SD = 2.16). Self-control was measured by the Brief Self-control Scale. Self-reported alcohol consumption on weekdays and in specific situations was converted into alcohol units. Participants who reported not drinking alcohol at all (55.6%) scored significantly higher in self-control. For those participants who reported drinking alcohol (44.4%), total self-control scores correlated moderately and inversely with alcohol consumption per week, in situations of stress, happiness, and when with friends. Standard multiple regression analysis revealed that self-control was a stronger predictor of the amount of alcohol consumed than were age and gender. The results are discussed with regard to the role of self-regulatory behaviour in the consumption of alcohol. Key words : Alcohol consumption, Botswana, self-control, self-regulation, undergraduate students
这项研究在博茨瓦纳大学的学生中探索了自我控制和饮酒之间的关系,并在自我调节的社会认知理论中得到了巩固。数据来自135名本科生,其中女生42.2%,男生57.8%,平均年龄21.22岁(SD = 2.16)。自我控制用简明自我控制量表进行测量。在工作日和特定情况下自我报告的饮酒量被转换成酒精单位。报告根本不喝酒的参与者(55.6%)在自我控制方面得分明显更高。对于那些报告饮酒的参与者(44.4%),在压力、快乐和与朋友在一起的情况下,自控力总分与每周饮酒量呈中等和负相关。标准多元回归分析显示,自我控制比年龄和性别更能预测饮酒量。研究结果讨论了自我调节行为在酒精消费中的作用。关键词:酒精消费博茨瓦纳自我控制自我调节大学生
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引用次数: 9
期刊
African Journal of Drug and Alcohol Studies
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