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Issues of self-education in the continuous professional development of dentists of Ukraine in the conditions of the Covid-19 pandemic 在2019冠状病毒病大流行的条件下乌克兰牙医持续专业发展的自我教育问题
Q4 Dentistry Pub Date : 2022-01-01 DOI: 10.5937/asn2285370m
I. Mazur, N. Hasiuk, I. Suprunovych, V. Radchuk, Petro Mazur
Background: The rapid development of the dental industry and the daily practice of dentists necessitate constant learning because replenishing the stock of acquired knowledge and skills is the basis for the formation of a highly qualified specialist. Self-directed learning, especially reading and purposeful work with medical literature, constantly contribute to the development of thinking, which should correspond to the modern level of science in medical professionals in the context of the Covid-19 pandemic. The aim of the study was to monitor and analyze ways to obtain new scientific and practical knowledge by dentists to improve their dental practice. Materials and methods: The study involved 4.026 dentists who filled out for dentists online. Results: To improve daily dental practice, dentists additionally use information that is provided in lectures at scientific and practical events (80.19%) and Internet resources (71.48%). For dentists, the most convenient way to read scientific and practical articles was through the electronic version on the websites of the journals (62.20%). Informing doctors with articles with well-illustrated clinical cases (72.66%) and lectures along with practical materials (64.75%) are of the greatest interest to the vast majority of dentists. Conclusion: According to the analytical results, it is shown that the main ways of obtaining scientific and practical information for dentists in the process of self-directed learning is the active involvement of the materials gained on the lectures, scientific and practical events, from Internet resources, from scientific and methodological literature, from scientific articles of domestic and foreign English-language professional journals.
背景:牙科行业的快速发展和牙医的日常实践需要不断学习,因为补充已获得的知识和技能是形成高素质专家的基础。自主学习,特别是阅读和有目的的医学文献工作,不断促进思维的发展,这应符合新冠肺炎大流行背景下医学专业人员的现代科学水平。该研究的目的是监测和分析牙医获得新的科学和实用知识的方法,以提高他们的牙科实践。材料和方法:该研究涉及4,026名牙医,他们在网上填写了牙医。结果:为了提高日常牙科实践水平,牙医还利用科学实践活动讲座提供的信息(80.19%)和互联网资源(71.48%)。对牙医而言,通过期刊网站的电子版阅读科学实用文章最方便(62.20%)。绝大多数牙医最感兴趣的是向医生提供有详细说明的临床病例的文章(72.66%)和讲座以及实用材料(64.75%)。结论:根据分析结果,牙医在自主学习过程中获取科学实用信息的主要途径是积极参与讲座、科学实践活动、网络资源、科学方法论文献、国内外英文专业期刊的科学文章等。
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引用次数: 0
Possible effects of hyperparathyroidism in the loss of osseointegration of dental implants: A case report 甲状旁腺功能亢进对牙种植体骨整合丧失的可能影响:1例报告
Q4 Dentistry Pub Date : 2022-01-01 DOI: 10.5937/asn2285389p
G. Petroni, L. Brodocz, Alfredo Passarett, A. Zanza, L. Testarelli, A. Cicconetti
Background: Hyperparathyroidism (HPT) is a common endocrine disorder with potential complications on the skeletal, renal, neurocognitive and cardiovascular systems. Its association with the lack of osseointegration of dental implants has not been described in the medical literature. Case presentation: This case report aims to discuss two cases of dental implant loss in which a high level of parathormone (PTH) was found in the absence of any other systemic or local comorbidity, suggesting the possible correlation between HPT and implant. Both patients were referred to the clinic complaining about prosthetic complications, gingival inflammation and mobility of the dental prosthesis. After a Cone-Beam computed Tomography evaluation, all implants of both patients were removed for rejection arising from periimplantitis and then four implants were inserted in the patient 1 and five implants in the patient 2. For both patients short implants (Bicon LLC, Boston, Massachusetts, USA), featured by 4 mm in diameter and 5 mm in height, were used and the prosthesis substructure was made of Trinia® (Bicon LLC, Boston, Massachusetts, USA). During the fifth year, the patients reported complications and the implant treatment failure. In order to establish the causes of failure, a thorough investigation was performed. Since no causes were detected, the patients were required to perform a blood test to evaluate bone metabolism and specifically to assess parathyroid-hormone levels (PTH), calcium levels and vitamin D. Results: The results of the blood tests showed normal calcemia, vitamin D deficiency and elevated PTH levels in both patients. After an endocrinologist's consultation, secondary hyperparathyroidism was diagnosed. Conclusion: It is reasonable to assume that the loss of osseointegration of dental implants can be correlated with the effects of HPT.
背景:甲状旁腺功能亢进(HPT)是一种常见的内分泌疾病,具有骨骼、肾脏、神经认知和心血管系统的潜在并发症。其与牙种植体缺乏骨整合的关系尚未在医学文献中描述。病例介绍:本病例报告旨在讨论两例种植体丢失的病例,其中高水平的甲状旁激素(PTH)被发现,没有任何其他全身或局部共病,提示HPT和种植体之间可能存在相关性。两名患者均因假体并发症、牙龈炎症和假体的可动性而就诊。在锥形束计算机断层扫描评估后,由于种植体周围炎引起的排斥反应,两例患者的所有种植体均被移除,然后患者1植入了4个种植体,患者2植入了5个种植体。两名患者均使用直径为4mm,高度为5mm的短种植体(Bicon LLC, Boston, Massachusetts, USA),假体亚结构由Trinia®(Bicon LLC, Boston, Massachusetts, USA)制成。在第五年,患者报告了并发症和种植体治疗失败。为了确定故障的原因,进行了彻底的调查。由于没有发现病因,因此要求患者进行血液检查以评估骨代谢,特别是评估甲状旁腺激素水平(PTH),钙水平和维生素D。结果:血液检查结果显示两例患者血钙正常,维生素D缺乏,PTH水平升高。经内分泌专家咨询后,诊断为继发性甲状旁腺功能亢进。结论:我们有理由认为种植体的骨整合丧失与HPT的效果有关。
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引用次数: 0
Modified direct orthodontic bonding metod: Effectiveness in orthodontic therapy: A retrospective clinical study 改良直接正畸粘接法:在正畸治疗中的有效性:回顾性临床研究
Q4 Dentistry Pub Date : 2022-01-01 DOI: 10.5937/asn2286441m
Vladimir D. Mitić, Suzana Ilić, Stefan Jovanović, Ivana N. Stoiljković
Background: The aim of the study was to determine the percentage of bond failures of placed brackets with a modified direct method in patients of both genders, different ages and malocclusion types during 12 months of initial bonding. Material and Methods: The retrospective clinical study covered the period from November 2019 to December 2022 and included thirty patients with an average age of 17.07±5.35 8 males,(average age 18.77±7.87), and 22 females, (average age 16.45±4.17) who met the criteria. A total of 600 brackets with a 0.022" slot size (Mini Sprint ® , Forestadent, Germany) were placed by a modified direct method using thin paste adhesive (Reliance Light Bond™, Itasca, USA) by one operator. The observation of bond failures lasted 12 months. Results: The total number of bond failures was 10 (1.67%), where eight patients (26,7%) experienced unwanted debonding. The number of failed brackets in relation to age and malocclusion did not show statistical significance. There was a clinical difference between the genders, in 18.2% of women and in 50% of men. Statistical significance in number of failed brackets was not significant (HR=0.343; 95% CI: 0.084-1.394; p=0.135). Conclusion: The modified direct bonding method did not show differences at the level of age, gender and type of malocclusion, but it can be one of the methods of choice during direct bonding.
背景:本研究的目的是测定不同性别、不同年龄、不同错颌类型的患者在初始粘接的12个月内,用改良的直接法对放置的托槽进行粘接失败的百分比。材料与方法:回顾性临床研究时间为2019年11月至2022年12月,纳入符合标准的30例患者,平均年龄17.07±5.35岁,男性8例(平均年龄18.77±7.87),女性22例(平均年龄16.45±4.17)。共有600个凹槽尺寸为0.022英寸的托架(Mini Sprint®,Forestadent,德国)由一家运营商使用薄膏状粘合剂(Reliance Light Bond™,Itasca,美国),通过改进的直接方法放置。债券违约的观察持续了12个月。结果:粘接失败10例(1.67%),其中8例(26.7%)出现不必要的脱粘。牙槽失败数与年龄、错颌的关系无统计学意义。男女之间存在临床差异,女性为18.2%,男性为50%。失效托槽数差异无统计学意义(HR=0.343;95% ci: 0.084-1.394;p = 0.135)。结论:改良后的直接粘接方法在年龄、性别、错牙合类型等方面均无差异,可作为直接粘接的首选方法之一。
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引用次数: 0
Oral leukoplakia: A review of clinical features and trends in management 口腔白斑:临床特点及治疗趋势综述
Q4 Dentistry Pub Date : 2022-01-01 DOI: 10.5937/asn2285417p
Vaibhav Pandita, Vidya Ajila, S. Babu, Shruthi S Hegde
Introduction: Oral potentially malignant disorders (OPMD) conisit of the group of diseases of great importance for dentists. Oral leukoplakia (OL) has long been the subject of debate by numerous researchers. A common etiologic factor is tobacco, which is associated with oral cancer. The aim of the study is to indicate the severity of the lesion, the most common clinical characreistics and localization. The prevalence of leukoplakia in the world is 2.6% with a rate of malignant conversion ranging from 0.1% to 17.5%. Literature data about the prevalence and annual rate of malignant transformation, approximately 2%, indicate that these changes should be taken seriously and regularymonitored Conclusion: Occurate diagnosis provides the key to preventing to malignant transformation. Various medical and surgical treatment modalities for this lesion have been described. This article highlights various trends in the diagnosis and treatment of oral leukoplakia.
口腔潜在恶性疾病(OPMD)是一组对牙医非常重要的疾病。口腔白斑(OL)一直是众多研究人员争论的主题。一个常见的病因是烟草,它与口腔癌有关。该研究的目的是表明病变的严重程度,最常见的临床特征和定位。世界上白斑的患病率为2.6%,恶性转换率为0.1%至17.5%。文献资料显示,恶性转化的患病率和年发病率约为2%,应引起重视并定期监测。结论:发生诊断是预防恶性转化的关键。已经描述了这种病变的各种医学和外科治疗方式。本文重点介绍了口腔白斑的诊断和治疗的各种趋势。
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引用次数: 0
The relationship between the level of periodontal pocket depth with gingival crevicular fluid weight using analytical balance as an indicator of periodontal tissue inflammation 牙周袋深度水平与龈沟液重量的关系用分析天平作为牙周组织炎症的指标
Q4 Dentistry Pub Date : 2022-01-01 DOI: 10.5937/asn2286479f
Malianawati Fauzia, Neny Roeswahjuni, Rahmavidyanti Priyanto, Ariyati Pratiwi, Novi Firani, Monica Amelia
Background: The present study aims to determine the relationship between the level of periodontal pocket depth with the weight of gingival crevicular fluid (GCF)using an analytical balance. Material and Methods: This is an observational analytic study with a cross-sectional approach. The level of periodontal pocket depth was analyzed by probing. Twenty-seven subjects were divided into three groups, namely, group 1 (with normal pocket depth: 0-3.5 mm), group 2 (pocket depth of 3.6-5.5 mm), and group 3 (pocket depth of more than 5.5 mm). GCF sampling was conducted by the infraclavicular method using paper points and its weight measurement wit han analytical balance. Data were analyzed by one-way analysis of variance followed by post hoc Tukey test to determine the comparison of GCF's weight between groups. The correlation was determined using the Pearson correlation test. Results: The average of GCF's weight obtained respectively in each group was 0.352 ± 0.09 mcg, 0.598 ± 0.10 mcg, and 0.899 ± 0.06 mcg. There was a significant difference (p < 0.001) with the highest GCF's weight was found in the pocket depth group >5.5 mm. The Pearson correlation test showed that there was a positive correlation between the depth of the periodontal pocket and the weight of GCF. Conclusion: The level of periodontal pocket depth is related to the weight of GCF.
背景:本研究旨在利用分析天平确定牙周袋深度水平与龈沟液(GCF)重量之间的关系。材料和方法:这是一项采用横断面方法的观察性分析研究。用探牙法分析牙周袋深度。将27名受试者分为3组,即1组(正常口袋深度0 ~ 3.5 mm)、2组(口袋深度3.6 ~ 5.5 mm)、3组(口袋深度大于5.5 mm)。GCF取样采用锁骨下法,采用纸点法,并用非分析天平测量其重量。采用单因素方差分析和事后Tukey检验比较各组间GCF的权重。使用Pearson相关检验确定相关性。结果:各组GCF体重平均值分别为0.352±0.09 mcg、0.598±0.10 mcg和0.899±0.06 mcg。两组间差异有统计学意义(p < 0.001),袋深组GCF重量最高,为5.5 mm。Pearson相关检验显示牙周袋深度与GCF重量呈正相关。结论:牙周袋深度的高低与GCF的重量有关。
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引用次数: 0
The influence of the inheritance on the occurrence of hypodontia and hyperdontia in children in the Federation of Bosnia and Herzegovina 遗传对波斯尼亚和黑塞哥维那联邦儿童下颌畸形和多牙畸形发生的影响
Q4 Dentistry Pub Date : 2022-01-01 DOI: 10.5937/asn2286489s
Mervana Dizdarević-Spahić
Purpose: The purpose of the research was to establish and mutually complement the frequency of hypodontia and hyperdontia in selected locations of Bosnia and Herzegovina, and to assess the participation of hereditary factors in the registered heterogeneity. Respondents and Procedures: A sample of 1,640 children of school age, both sexes, aged 12-14, served as the subject of research. The sample was collected from five urban centers in the Federation of Bosnia and Herzegovina: Sarajevo, Mostar, Tuzla, Bihać and Gorazde. In order to estimate the difference in the number of respondents by sex, as well as in assessing the differences in the frequency of observed anomalies (hyperdontia and hypodontia), a ch 2 test with a statistical significance limit p <0.05 was applied. The Fisher Exact Test was used to assess the correlation between the occurrence of hyperdontia and hypodontia between children and parents. Scientifically verified ver. Ver. MedCalc 11.5.0.0. In order to evaluate the distinction between possible hereditary and non-positive factors, an assessment of heritability was performed (h) by applying regression analysis (parent-offspring regression). Results: A total of 40 children with anomalies of the number of teeth were identified, of which 16 boys and 24 girls. There was no statistically significant difference in the frequency of hypodontia and hyperdontia between boys and girls with respect to geographic regions (ch 2 = 0.500; P = 0.9735). Conclusion: The total prevalence of hypodontia and hyperdontia was 2.43. The prevalence of hypodontia is 1.58, and the hyperdontia is 0.85. The relative risk of anomalies in the number of teeth in children is 8,965 and is statistically significant, indicating that the likelihood of the occurrence of this disorder in children whose at least one parent has the same anomaly is greater.
目的:本研究的目的是在波斯尼亚和黑塞哥维那选定的地区建立和相互补充下颌畸形和多牙畸形的频率,并评估遗传因素在登记异质性中的作用。调查对象和程序:样本为1640名学龄儿童,男女,12-14岁,作为研究的主题。样本是从波斯尼亚-黑塞哥维那联邦的五个城市中心收集的:萨拉热窝、莫斯塔尔、图兹拉、比哈奇和戈拉日德。为了估计按性别划分的应答者数量的差异,以及评估观察到的异常(多牙症和下牙症)频率的差异,采用了具有统计学意义极限p <0.05的ch 2检验。使用Fisher精确检验来评估儿童和父母之间牙多和牙下畸形的发生之间的相关性。经过科学验证。版本。MedCalc 11.5.0.0。为了评估可能的遗传因素和非积极因素之间的区别,采用回归分析(亲代回归)对遗传力进行评估(h)。结果:共检出畸牙数患儿40例,其中男孩16例,女孩24例。在不同的地理区域,男孩和女孩的牙下和牙多症发生的频率没有统计学差异(ch2 = 0.500;P = 0.9735)。结论:牙下、牙多症总患病率为2.43。牙下畸形的患病率为1.58,牙多畸形的患病率为0.85。儿童牙齿数量异常的相对风险为8,965,具有统计学意义,表明父母中至少有一方具有相同异常的儿童发生这种疾病的可能性更大。
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引用次数: 0
A trio of talon's cusp on a fused maxillary central incisor: A unique presentation 在融合的上颌中切牙上的三个爪尖:一种独特的表现
Q4 Dentistry Pub Date : 2022-01-01 DOI: 10.5937/asn2286513d
D. Darwin, R. Castelino, Babu Subhas, Chitharanjan Shetty
Introduction: Odontogenic malformations of teeth can be frequently encountered affecting both the primary and permanent dentition. The co-occurrence of talon cusp in a fused tooth, however, is an uncommon developmental dental aberration that necessitates a variety of prophylactic procedures to minimize potential consequences. Often, the presence of talon's cusp can result in pulpal necrosis due to its deep extension, which increases functional complexity. Methods: The present case describes the fusion of a supplemental tooth to a maxillary permanent tooth in conjunction with multiple talon's cusps on labial and palatal aspects which is an extremely rare entity and first of its kind. Results: Endodontic management followed by esthetic reconstruction of the affected tooth is considered as the standard treatment in cases of pulpal involvement of any odontogenically malformed tooth. Our case also demonstrates the establishment of an accurate diagnosis using a three-dimensional imaging modality by overcoming the challenges of periapical radiographs. Conclusion: In addition to diagnosis, practitioners should also have an in-depth understanding of the origin, prevalence, clinical and radiographic characteristics of odontogenic malformations, which AIDS in an effective treatment strategy.
牙源性畸形是一种常见的影响恒牙和初级牙列的疾病。然而,在融合牙中同时出现爪尖是一种罕见的发育性牙齿畸变,需要采取各种预防措施以尽量减少潜在的后果。通常,爪尖的存在可导致牙髓坏死,因为它的深度延伸,这增加了功能的复杂性。方法:本病例描述了上颌恒牙的补充牙融合与多个爪尖在唇和腭方面,这是一个极其罕见的实体和其类型的第一次。结果:对于牙源性畸形牙累及牙髓的病例,牙髓治疗后的美观重建是标准的治疗方法。我们的病例也证明了通过克服根尖周围x线片的挑战,利用三维成像模式建立准确的诊断。结论:医师在诊断牙源性畸形的同时,还应深入了解牙源性畸形的起源、流行、临床和影像学特征,以便制定有效的治疗策略。
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引用次数: 0
Morphological characteristics of the lip grooves in citizens of the Republic of North Macedonia determined by Cheiloscopy 用唇镜测定北马其顿共和国公民唇沟的形态学特征
Q4 Dentistry Pub Date : 2022-01-01 DOI: 10.5937/asn2286456p
Bojan Poposki, Naida Babić-Jordamović, K. Ivanovski, Ana Pejčić, V. Kokolanski, D. Marjanovic, Aneta S. Atanasovska-Stojanovska, Zlatko Jakjovski
Introduction: Cheiloscopy is defined as the study of the sulci labiorum, known as "lip prints". Aim of the study: The aim of this study was to determine the morphological characteristics of the lip grooves in the three dominant nationalities in the Republic of North Macedonia (Macedonians, Albanians, Roma) and to compare the obtained results with the morphological characteristics of the lip grooves in three other populations from different geographical regions. Material and methods: In this research, we included 150 examinees aged 25-50 years and divided them into three groups: Macedonians (50), Albanians (50) and Roma (50). The lip prints were taken using microscopic slides and detected using the dactyloscopic powder and brush method. We used the Suzuki and Tsuchihashi classification to typify the lip prints. Results: The most common type of lip grooves in the population of the Republic of North Macedonia was the type II grooves. There was no significant difference in the presence of different types of lip grooves in the four quadrants between males and females, nor between Macedonians, Albanians and Roma. The comparative analysis showed that populations from different geographical areas had different anthropological and morphological characteristics of the lip grooves. Conclusion: Type II lip grooves are the most common in the population of the Republic of North Macedonia and there is no statistically significant difference between the prevalence of different types of lip grooves in the three nationalities in this study. Considering the large number of factors that can affect the quality of the lip print, we recommend that a swab should always be taken before collecting the lip print in order to attempt to extract DNA material from the found trace.
导读:唇镜检查被定义为研究唇沟,被称为“唇印”。研究目的:本研究的目的是确定北马其顿共和国三个主要民族(马其顿人、阿尔巴尼亚人、罗姆人)的唇槽形态特征,并将所得结果与来自不同地理区域的其他三个人群的唇槽形态特征进行比较。材料和方法:在本研究中,我们纳入了150名年龄在25-50岁之间的考生,并将他们分为三组:马其顿人(50),阿尔巴尼亚人(50)和罗姆人(50)。用显微载玻片取唇印,用指指镜粉刷法检测唇印。我们使用铃木和土桥分类来对唇印进行分类。结果:北马其顿共和国人群中最常见的唇沟类型为II型唇沟。在四个象限中,男性和女性之间,以及马其顿人、阿尔巴尼亚人和罗姆人之间,不同类型唇槽的存在没有显著差异。对比分析表明,不同地理区域的人群具有不同的唇沟人类学和形态学特征。结论:II型唇沟在北马其顿共和国人群中最为常见,本研究中三个民族不同类型唇沟的患病率差异无统计学意义。考虑到影响唇印质量的因素有很多,我们建议在采集唇印之前先用棉签擦拭,以便从发现的痕迹中提取DNA物质。
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引用次数: 0
Maxillary mesiodens in late medieval age archaeological skeletal remains from Rudina, Croatia 克罗地亚鲁迪纳中世纪晚期考古骸骨中的上颌中齿动物
Q4 Dentistry Pub Date : 2022-01-01 DOI: 10.5937/asn2286505b
Luka Banjšak, Vlasta Viroubal, Tomislav Katanec, Ante Miličević
Introduction: The occurrence of mesiodens is somewhat rare, but amongpatients with any kind of supernumerary teeth, it is rather common. From an anthropological point of view, it is interesting to confirm the development of mesiodens in various historical ages. Case report analyses a mesiodens and the surrounding skeletal remains dating from the late medieval ages (13th -16th centuries) which confirms the incidence of the mesiodens and presents the conclusion that historically, mesiodens, as a form of supernumerary teeth has been present throughout history. Conclusion finding of a mesiodens in an archaeological context proves that the occurrence of this type of accessory teeth has been present for at least half a millennium.
简介:中缺牙的发生比较少见,但在任何种类的多牙患者中,都是相当常见的。从人类学的角度来看,确认中碘片在不同历史时期的发展是很有趣的。病例报告分析了一颗中齿齿和周围可追溯到中世纪晚期(13 -16世纪)的骨骼遗骸,证实了中齿齿的存在,并得出结论,从历史上看,中齿齿作为一种多余牙齿一直存在于整个历史中。结论:在考古背景下发现的一颗中齿证明,这种副牙的出现至少已经存在了半个世纪。
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引用次数: 0
Oral pyogenic granuloma: A case report and review of literature 口腔化脓性肉芽肿1例报告及文献复习
Q4 Dentistry Pub Date : 2022-01-01 DOI: 10.5937/asn2285381a
S. Achalli, Murali Patia
Uvod: Pyogenic granuloma is a common non neoplastic growth in the oral cavity which is hyperplastic in nature. Various theories of etiopathogenesis have been suggested for pyogenic granuloma. It is commonly thought to be a response to various local irritants like calculus, foreign body material etc. It is hemorrhagic and often bleeds on touch. It usually causes local interference. Excisional biopsy is considered the treatment of choice for pyogenic granuloma followed by removal of the local irritants in order to avoid recurrence. This article presents a case of oral pyogenic granuloma in a 54-year-old patient in the gingiva extending up to the palate with a review of literature. Materials and methods: A thorough case history and clinical examination was done. A provisional diagnosis of pyogenic granuloma was given. Excisional biopsy was performed and the lesion was sent for histopathological evaluation. Result: Histopathological examination of the lesion confirmed the clinical diagnosis of pyogenic granuloma. Conclusion: Pyogenic granuloma is non neoplastic in nature and hence a detailed knowledge of this lesion is required in order to identify it in its early stage and to manage it appropriately before it causes any hindrance in normal routine functions.
化脓性肉芽肿是口腔中一种常见的非肿瘤性增生。关于化脓性肉芽肿的发病机制有多种说法。它通常被认为是对各种局部刺激物的反应,如结石、异物等。它是出血性的,经常一接触就出血。它通常会引起局部干扰。切除活检被认为是治疗化脓性肉芽肿的选择,然后去除局部刺激物,以避免复发。这篇文章提出一个病例口腔化脓性肉芽肿在一个54岁的病人在牙龈延伸到上颚与文献回顾。材料和方法:对患者进行了详细的病史和临床检查。初步诊断为化脓性肉芽肿。切除活检,病变送组织病理评估。结果:组织病理学检查证实化脓性肉芽肿的临床诊断。结论:化脓性肉芽肿本质上是非肿瘤性的,因此需要对这种病变有详细的了解,以便在早期发现它,并在它对正常的日常功能造成任何阻碍之前适当地处理它。
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引用次数: 0
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