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Mortality Statistics in Asthma. 哮喘死亡率统计。
Q3 Medicine Pub Date : 2023-01-01 DOI: 10.17849/insm-49-04-244-249.1
Rodney C Richie

This article summarizes the mortality associated with asthma and was created from a presentation given at the 130th AAIM Annual Meeting.

这篇文章总结了与哮喘相关的死亡率,并根据第130届AAIM年会上的一份报告创建。
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引用次数: 0
Normal Transaminases in Methamphetamine- and Heroin-Associated Hyperammonemic Encephalopathy. 甲基苯丙胺和海洛因相关性高氨血症脑病的正常转氨酶。
Q3 Medicine Pub Date : 2023-01-01 DOI: 10.17849/insm-49-4-2-4.1
Vera F Dolan

Detecting undisclosed methamphetamine and heroin abuse is a challenge for life underwriters and medical directors. A common clinical assumption is that if substance abusers experience liver damage, it will be indicated by elevated serum transaminases. The following case suggests that assumption may not be true for heavy substance abusers who consume no or minimal alcohol. This report describes a 44-year-old male with long-term use of inhaled combined methamphetamine and heroin ("speedballs") and minimal alcohol use, whose transaminases remained normal while episodes of acute liver failure and transient hepatic encephalopathy from hyperammonemia were observed. In this case, a fatal motor vehicle accident occurred following the sudden onset of hepatic encephalopathy hours after consuming a "speedball." Normal transaminases may not be proof of a normal healthy liver among methamphetamine and heroin abusers.

检测未公开的甲基苯丙胺和海洛因滥用对寿险保险公司和医疗主管来说是一个挑战。一个常见的临床假设是,如果药物滥用者经历肝损害,它将表明血清转氨酶升高。下面的案例表明,对于不饮酒或少量饮酒的重度药物滥用者来说,这种假设可能不成立。本报告描述了一名44岁男性,长期吸入甲基苯丙胺和海洛因(“速球”)并少量饮酒,其转氨酶保持正常,但观察到急性肝功能衰竭和高氨血症引起的一过性肝性脑病发作。在这个案例中,一个致命的机动车事故发生在肝性脑病的突然发作数小时后,食用“速度球”。在甲基苯丙胺和海洛因滥用者中,正常的转氨酶可能不是肝脏正常健康的证明。
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引用次数: 0
Critical Illness at 40: Still a Thorn in the Medical Director's Side. 40岁时的危重疾病:仍然是医学主任的眼中钉。
Q3 Medicine Pub Date : 2023-01-01 DOI: 10.17849/insm-49-4-3-3.1
Timothy Meagher

Critical illness insurance was introduced 40 years ago. Medical directors continue to be challenged and frustrated with the complexities that critical illness claims offer. This article provides insights into the continued issues and possible solutions.

重病保险是40年前推出的。医疗主管继续受到挑战和沮丧的复杂性,危重疾病索赔提供。本文提供了对持续存在的问题和可能的解决方案的见解。
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引用次数: 0
Morbidity and Mortality Associated with Chronic Obstructive Pulmonary Disease (COPD). 慢性阻塞性肺疾病(COPD)的发病率和死亡率。
Q3 Medicine Pub Date : 2023-01-01 DOI: 10.17849/insm-49-04-230-243.1
Rodney C Richie

This article summarizes the morbidity and mortality associated with COPD and was created from a presentation given at the 130th AAIM Annual Meeting. The author reviews what most medical directors already know about COPD, but with particular attention paid to the Pulmonary Function Tests dealing with spirometry. Underwriters and medical directors need to understand the three basic measurements of spirometry (FVC, FEV1, and FEF25-75), as well as the significance of the FEV1/FVC ratio, in establishing an applicant as having an obstructive or restrictive impairment.

这篇文章总结了COPD相关的发病率和死亡率,是根据第130届AAIM年会上的一份报告编写的。作者回顾了大多数医学主任已经知道的关于慢性阻塞性肺病,但特别关注肺功能测试处理肺活量测定。承保人和医疗主管需要了解肺活量测定法的三个基本测量值(FVC、FEV1和FEF25-75),以及FEV1/FVC比值在确定申请人是否患有阻塞性或限制性损伤方面的重要性。
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引用次数: 0
JIM Reading List. 吉姆阅读清单。
Q3 Medicine Pub Date : 2023-01-01 DOI: 10.17849/insm-49-04-254-258.1
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引用次数: 0
Association of Liver Function Tests with Mortality in an Insurance Applicant Population. 保险申请人人群中肝功能检测与死亡率的关系
Q3 Medicine Pub Date : 2022-07-01 DOI: 10.17849/insm-49-3-172-182.1
Steven J Rigatti, Robert Stout

Objectives: -Determine the relationship between liver function test (LFT) results (GGT, alkaline phosphatase, AST, ALT and albumin) and all-cause mortality in life insurance applicants.

Method: -By use of the Social Security Master Death File, mortality was examined in 15,272,955 insurance applicants for whom blood samples were submitted to the Clinical Reference Laboratory. There were 268,593 deaths observed in this study population, after an average follow-up time of 10.9 years. Results were stratified by sex and by age less/greater than 60, creating 4 groups. Liver function test values were grouped using percentiles of their distribution within these age/ sex groups - so as to update the results generated in prior publications. Additional models were fit using different exclusions and percentile groups within single year age groups. Also, LFTs were treated as continuous variables and included in Cox models with age and smoking status.

Results: -Using the risk of the middle 50% of the population by distribution as a reference, relative mortality observed for GGT and alkaline phosphatase was linear with a steep slope from very low to high values. AST showed a J-shaped association with mortality. ALT showed a low-magnitude inverse correlation with mortality. Albumin demonstrated a higher-magnitude inverse correlation with mortality, especially at values below the median. The overall risk associated with LFTs was durable over at least 10 years of follow-up.

Conclusion: -Liver function tests show a strong and durable correlation to mortality in a large group of insurance applicants. The durability over time suggests that even older values of LFTs found in medical records could be of use in mortality risk prediction.

目的:确定寿险申请人肝功能检查(LFT)结果(GGT、碱性磷酸酶、AST、ALT和白蛋白)与全因死亡率之间的关系。方法:-通过使用社会保障总死亡档案,对15,272,955名投保人的死亡率进行了检查,他们的血液样本被提交给临床参考实验室。在平均10.9年的随访时间后,在该研究人群中观察到268,593例死亡。结果按性别、60岁以下/ 60岁以上年龄分层,分为4组。在这些年龄/性别组中使用其分布的百分位数对肝功能测试值进行分组,以便更新先前出版物中产生的结果。其他模型在单年年龄组中使用不同的排除和百分位数组进行拟合。此外,LFTs被视为连续变量,并与年龄和吸烟状况一起纳入Cox模型。结果:-以分布人群中中间50%的风险为参照,GGT和碱性磷酸酶的相对死亡率呈线性关系,从非常低的值到高的值呈陡斜率。AST与死亡率呈j型相关。ALT与死亡率呈低幅度负相关。白蛋白与死亡率呈较高的负相关,特别是在低于中位数的值时。与LFTs相关的总体风险在至少10年的随访中持续存在。结论:-肝功能测试显示,在一大群保险申请人中,肝功能测试与死亡率有很强且持久的相关性。随着时间的推移,即使是在医疗记录中发现的更古老的LFTs值也可能用于死亡率风险预测。
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引用次数: 0
Cancers of the Oral Cavity and Pharynx: 20-Year Comparative Survival and Mortality Analysis by Age, Sex, Race, Stage, Grade, Cohort Entry Time-Period and Disease Duration: A Systematic Review of 218,066 Cases for Diagnosis Years 1973-2014: (SEER*Stat 8.3.5). 口腔癌和咽癌:按年龄、性别、种族、分期、分级、队列入组时间和病程划分的20年生存率和死亡率比较分析:1973-2014年218066例诊断病例的系统评价:(SEER*Stat 8.3.5)。
Q3 Medicine Pub Date : 2022-07-01 DOI: 10.17849/insm-49-3-147-171.1
Anthony F Milano

This article summarizes the results of a retrospective population-based cohort study using the statistical database of SEER*Stat 8.3.54 (produced 3/5/2018 for diagnosis years 1973-2014) to assess, determine, compare, and summarize the occurrence, long-term survival, and mortality indices of 218,066 patients with oral cavity and pharynx cancers by age, sex, race, stage, grade, and disease duration.

本文利用SEER*Stat 8.3.54统计数据库(3/5/2018,诊断年为1973-2014年)对218066例口腔癌和咽喉癌患者的年龄、性别、种族、分期、分级、病程进行回顾性人群队列研究,评估、确定、比较和总结其发生、长期生存和死亡指标。
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引用次数: 0
Cancer of the Rectum and Rectosigmoid Junction: 20-Year Comparative Survival and Mortality Analysis by Age, Sex, Race, Stage, Grade, Cohort Entry Time-Period and Disease Duration: A Systematic Review of 266,898 Cases for Diagnosis Years 1973-2014: (SEER*Stat 8.3.4). 直肠和直肠乙状结肠结癌:20年生存率和死亡率比较分析,包括年龄、性别、种族、分期、分级、队列进入时间和疾病持续时间:1973-2014年266,898例诊断病例的系统回顾(SEER*Stat 8.3.4)。
Q3 Medicine Pub Date : 2022-07-01 DOI: 10.17849/insm-49-3-126-146.1
Anthony F Milano

This article reviews a 20-year retrospective population-based study using the statistical database of SEER*Stat 8.3.4 to compare the occurrence, long-term survival and mortality indices of 266,898 patients with cancer of the rectum and rectosigmoid junction (RSJ) juxtaposed by age, sex, race, stage, grade, disease duration, in two cohort entry time-periods, 1973-1994 & 1995-2014.

本文采用SEER*Stat 8.3.4统计数据库,回顾了一项基于20年人群的回顾性研究,比较了1973-1994年和1995-2014年两个队列进入时期266,898例直肠及直肠乙状结肠结癌(RSJ)患者的发病率、长期生存率和死亡率指标,这些指标按年龄、性别、种族、分期、分级、病程并列。
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引用次数: 1
JIM Reading List. JIM阅读列表。
Q3 Medicine Pub Date : 2022-07-01 DOI: 10.17849/insm-49-3-200-204.1
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引用次数: 0
Checking the Pulse: A Global Survey on the Evolving Roles of the Insurance Medical Director. 检查脉搏:关于保险医疗主管角色演变的全球调查。
Q3 Medicine Pub Date : 2022-07-01 DOI: 10.17849/insm-49-3-1-11.1
Sheetal S Salgaonkar, Leigh Allen, Daniel Zimmerman

Background and objective: -The traditional role of the insurance medical director is evolving. RGA surveyed insurance medical directors to provide an overview of their roles, skill sets, future trends, and their increasing and changing contributions to the insurance industry in recent years and throughout the current pandemic.

Method: -RGA conducted a first-of-a-kind global survey of medical directors in the insurance industry. The online survey took place from April to June 2021 and had seven key sections: medical experience and qualifications, roles and responsibilities, underwriting and claims capabilities, adapting to change, disease and product trends in insurance, challenges, and future opportunities. Globally, 124 insurance medical directors from 84 companies participated in the survey.

Results: -Respondents are an experienced group of medical directors, with 88% active in the medical profession for 10 years or more. Eighty-seven respondents (70%) dedicate the majority of their time to providing technical medical expertise. Forty-eight percent of medical directors were involved in medical issue briefings prior to the pandemic, and that number increased to 63% during the pandemic. Three of every five respondents (60%) reported a shift in underwriting to an emphasis on more competitive decisions, e-underwriting, and data analytics, while for claims practices, 35% reported a shift to more decisions being challenged and increasing complexity of claims and products. In addition, 31% of insurance medical directors are involved in product development on a regular basis. Only 50% of respondents reported a high or moderate level of investment from employers for training and development with their companies. Forty-three percent of survey respondents are interested in a change of role, especially those with less than 15 years of experience in the insurance industry. Medical directors see data and analytics (50%) as the largest area of development for future growth. Eighty-eight percent of participants surveyed believe that the future role of the medical director in the life and health insurance industry is promising.

Conclusion: -The future of the medical director role will require more strategic responsibilities, greater product development expertise, and stronger data and analytics skills to support insurer needs. It will be important for insurance medical directors to engage in conversations with their employers to discuss their current and emerging roles.

背景和目的:-保险医疗主任的传统角色正在演变。RGA对保险公司的医疗主管进行了调查,概述了他们的作用、技能、未来趋势,以及他们近年来和在当前大流行期间对保险业不断增加和不断变化的贡献。方法:rga对保险行业的医疗主管进行了首次全球调查。该在线调查于2021年4月至6月进行,分为七个关键部分:医疗经验和资格、角色和责任、承保和索赔能力、适应变化、保险中的疾病和产品趋势、挑战和未来机遇。来自全球84家保险公司的124名医疗主管参与了此次调查。结果:受访者是一群经验丰富的医疗主任,88%的人在医疗行业活跃了10年或以上。87名受访者(70%)将大部分时间用于提供技术医疗专业知识。在大流行之前,48%的医务主任参与了医疗问题简报,在大流行期间,这一数字增加到63%。五分之三的受访者(60%)表示,承保业务转向强调更具竞争力的决策、电子承保和数据分析,而在索赔实践方面,35%的受访者表示,更多的决策受到挑战,索赔和产品的复杂性也在增加。此外,31%的保险医疗主管定期参与产品开发。只有50%的受访者表示,雇主对其公司的培训和发展进行了高或中等水平的投资。43%的受访者对转变角色感兴趣,尤其是那些在保险行业工作不到15年的人。医疗主管将数据和分析(50%)视为未来增长的最大发展领域。88%的受访者认为,医疗总监在生命和健康保险行业的未来角色是有前途的。结论:-未来的医疗总监角色将需要更多的战略责任,更强的产品开发专业知识,以及更强的数据和分析技能,以支持保险公司的需求。对于保险公司的医疗主管来说,与雇主进行对话,讨论他们目前和未来的角色是很重要的。
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Journal of insurance medicine (New York, N.Y.)
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