Pub Date : 2024-12-05DOI: 10.1016/j.hipert.2024.10.004
A Bustos-Merlo, D Rico-López, F Jaén-Águila, C López-Espada, M I Rodríguez-Macías, J D Mediavilla-García
The number of patients suffering from refractory hypertension and advanced-stage chronic heart failure (CHF) is progressively increasing. In recent years, device-mediated therapies have been developed as an alternative or adjunct to conventional medical treatment. Our primary objective is to describe the clinical experience in a series of patients with refractory hypertension following the implantation of baroreceptor activation therapy (BAT). We analyzed 5 patients with refractory hypertension, one of whom also had CHF, treated in a specialized cardiovascular risk clinic. After the implantation of the Barostim device with an average activation of 3.64mA (ranging from 2.80 to 5.4), there was a mean reduction of 30±7.68mmHg (P=0.001) and 13.40±9.07mmHg (P=0.03) in systolic and diastolic blood pressure, respectively, as measured by ambulatory blood pressure monitoring (ABPM), along with a heart rate reduction of 25±9.13 bpm (P=0.004). A reduction in the number of antihypertensive medications required for blood pressure control was observed, with an average of 5.2 medications, as well as an improvement in functional class. No adverse events were recorded in our patient series. Currently, BAT is considered a compassionate-use alternative for blood pressure control in patients with refractory hypertension and failure of pharmacological treatment and other invasive techniques, such as renal denervation.
{"title":"[Real-world efficacy and safety of baroreceptor activation therapy in a series of patients with refractory arterial hypertension].","authors":"A Bustos-Merlo, D Rico-López, F Jaén-Águila, C López-Espada, M I Rodríguez-Macías, J D Mediavilla-García","doi":"10.1016/j.hipert.2024.10.004","DOIUrl":"https://doi.org/10.1016/j.hipert.2024.10.004","url":null,"abstract":"<p><p>The number of patients suffering from refractory hypertension and advanced-stage chronic heart failure (CHF) is progressively increasing. In recent years, device-mediated therapies have been developed as an alternative or adjunct to conventional medical treatment. Our primary objective is to describe the clinical experience in a series of patients with refractory hypertension following the implantation of baroreceptor activation therapy (BAT). We analyzed 5 patients with refractory hypertension, one of whom also had CHF, treated in a specialized cardiovascular risk clinic. After the implantation of the Barostim device with an average activation of 3.64mA (ranging from 2.80 to 5.4), there was a mean reduction of 30±7.68mmHg (P=0.001) and 13.40±9.07mmHg (P=0.03) in systolic and diastolic blood pressure, respectively, as measured by ambulatory blood pressure monitoring (ABPM), along with a heart rate reduction of 25±9.13 bpm (P=0.004). A reduction in the number of antihypertensive medications required for blood pressure control was observed, with an average of 5.2 medications, as well as an improvement in functional class. No adverse events were recorded in our patient series. Currently, BAT is considered a compassionate-use alternative for blood pressure control in patients with refractory hypertension and failure of pharmacological treatment and other invasive techniques, such as renal denervation.</p>","PeriodicalId":39403,"journal":{"name":"Hipertension y Riesgo Vascular","volume":" ","pages":""},"PeriodicalIF":1.2,"publicationDate":"2024-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142792480","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-11-25DOI: 10.1016/j.hipert.2024.10.002
E P Antunes, W R Tebar, G G Cucato, C C M Silva, I Leoci, A B Dos Santos, G Ferrari, D G D Christofaro
Background: Sedentary behavior (SB) has been related to cardiovascular risk factors (CVRF) such as high BMI, waist circumference (WC) and blood pressure (BP), including pediatric populations. However, it is still unclear whether the association between SB and CVRF could be domain dependent. Therefore, this study aimed to analyze the relationship between sedentary at different domains (time spent in TV, videogames, computer, smartphone) with CVRF in adolescents.
Methods: A sample of 1011 adolescents (10-17 years old; 55.1% girls) was assessed. The different BS domains were obtained through a questionnaire, as well as socioeconomic status, habitual physical activity, smoking and alcohol consumption. BMI was calculated by objectively measured height and body mass, WC was assessed at middle point between the last rib and iliac crest, and BP was assessed by a digital oscillometric device. The relationship between SB and CVRF was determined by quantile regression, adjusted for sex, age, socioeconomic status, physical activity, smoking and alcohol consumption.
Results: Elevated time in smartphone use was associated with higher median values of WC (β=1.88; 95%CI: (0.27; 3.49) and SBP (β=2.70; 95%CI: 0.35; 5.05). High total time spent in SB was associated with higher median values of BMI (β=0.68; 95%CI=(0.02; 1.35), WC (β=1.95; 95%=0.47; 3.42) and SBP (β=2.52; 95%CI: 0.37; 4.68).
Conclusions: Smartphone use and total SB time were related to higher CVRF in adolescents. Cardiovascular health promotion strategies should focus on reducing SB in pediatric populations, especially smartphone use.
{"title":"Association of different domains of sedentary behavior and cardiovascular risk factors in adolescents: Cross-sectional study.","authors":"E P Antunes, W R Tebar, G G Cucato, C C M Silva, I Leoci, A B Dos Santos, G Ferrari, D G D Christofaro","doi":"10.1016/j.hipert.2024.10.002","DOIUrl":"https://doi.org/10.1016/j.hipert.2024.10.002","url":null,"abstract":"<p><strong>Background: </strong>Sedentary behavior (SB) has been related to cardiovascular risk factors (CVRF) such as high BMI, waist circumference (WC) and blood pressure (BP), including pediatric populations. However, it is still unclear whether the association between SB and CVRF could be domain dependent. Therefore, this study aimed to analyze the relationship between sedentary at different domains (time spent in TV, videogames, computer, smartphone) with CVRF in adolescents.</p><p><strong>Methods: </strong>A sample of 1011 adolescents (10-17 years old; 55.1% girls) was assessed. The different BS domains were obtained through a questionnaire, as well as socioeconomic status, habitual physical activity, smoking and alcohol consumption. BMI was calculated by objectively measured height and body mass, WC was assessed at middle point between the last rib and iliac crest, and BP was assessed by a digital oscillometric device. The relationship between SB and CVRF was determined by quantile regression, adjusted for sex, age, socioeconomic status, physical activity, smoking and alcohol consumption.</p><p><strong>Results: </strong>Elevated time in smartphone use was associated with higher median values of WC (β=1.88; 95%CI: (0.27; 3.49) and SBP (β=2.70; 95%CI: 0.35; 5.05). High total time spent in SB was associated with higher median values of BMI (β=0.68; 95%CI=(0.02; 1.35), WC (β=1.95; 95%=0.47; 3.42) and SBP (β=2.52; 95%CI: 0.37; 4.68).</p><p><strong>Conclusions: </strong>Smartphone use and total SB time were related to higher CVRF in adolescents. Cardiovascular health promotion strategies should focus on reducing SB in pediatric populations, especially smartphone use.</p>","PeriodicalId":39403,"journal":{"name":"Hipertension y Riesgo Vascular","volume":" ","pages":""},"PeriodicalIF":1.2,"publicationDate":"2024-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142733131","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-10-01DOI: 10.1016/j.hipert.2024.07.003
{"title":"Efecto de diferentes bebidas alcohólicas sobre la presión arterial","authors":"","doi":"10.1016/j.hipert.2024.07.003","DOIUrl":"10.1016/j.hipert.2024.07.003","url":null,"abstract":"","PeriodicalId":39403,"journal":{"name":"Hipertension y Riesgo Vascular","volume":"41 4","pages":"Pages 270-271"},"PeriodicalIF":1.2,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142663014","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-10-01DOI: 10.1016/j.hipert.2024.06.005
A. Delucchi, D. Fernández, M. Sorini, P. Reisin, M. Scarabino, P. Rodríguez
The inter-arm difference (IAD) of systolic blood pressure (SBP) is associated with higher cardiovascular risk. We compared simultaneous and consecutive recordings in measuring IAD of SBP, and evaluated reproducibility between visits. 143 hypertensive patients (63.8 ± 9.5 years, 51.7% women) treated and controlled with stable antihypertensive medication for a period of ≥ 3 months were included. Blood pressure (BP) in both arms was measured simultaneously and consecutively with an automatic oscillometric device, in two visits. The IAD of the simultaneous SBP was significantly lower compared to the consecutive one, both in the first (3.51 ± 4.1 vs. 4.40 ± 3.7 mmHg; P < .01) and in the second visit (3.62 ± 3.5 vs. 5.69 ± 5.1 mmHg; P < .001). When the IAD of SBP was categorized as ≥ 10 or < 10 mmHg, the reproducibility between visits was insignificant in both simultaneous measurements and consecutive measurements. The frequency of initial dominance was similar between the left and right arm in simultaneous ones (46.2 vs. 43.3%), and greater in the right arm in consecutive ones (55.2 vs. 38.5). The persistence of dominance between both visits was significantly higher when SBP was measured simultaneously (54.4% vs. 45.5%; P < .01). Our study shows that to define the arm with the highest BP, simultaneous measurements are preferable. In treated and controlled hypertensive patients, the poor persistence of initial dominance between visits requires us to review the recommendation of recording, during follow-up, the BP in the arm where it was highest on the first visit.
收缩压（SBP）的臂间差（IAD）与较高的心血管风险有关。我们比较了同时和连续记录 SBP 的 IAD 测量值，并评估了各次访问之间的重现性。共纳入 143 名高血压患者（63.8±9.5 岁，51.7% 为女性），这些患者均接受过稳定的降压药物治疗，且控制时间≥3 个月。两组患者的血压（BP）均由自动示波仪同时连续测量，分两次进行。同时测量的 SBP 的 IAD 值明显低于连续测量的 SBP 的 IAD 值（3.51±4.1 vs. 4.40±3.7 mmHg; P
{"title":"Diferencia de presión arterial entre brazos: mediciones consecutivas versus simultáneas en pacientes hipertensos tratados y controlados","authors":"A. Delucchi, D. Fernández, M. Sorini, P. Reisin, M. Scarabino, P. Rodríguez","doi":"10.1016/j.hipert.2024.06.005","DOIUrl":"10.1016/j.hipert.2024.06.005","url":null,"abstract":"<div><div>The inter-arm difference (IAD) of systolic blood pressure (SBP) is associated with higher cardiovascular risk. We compared simultaneous and consecutive recordings in measuring IAD of SBP, and evaluated reproducibility between visits. 143 hypertensive patients (63.8<!--> <!-->±<!--> <!-->9.5 years, 51.7% women) treated and controlled with stable antihypertensive medication for a period of ≥<!--> <!-->3 months were included. Blood pressure (BP) in both arms was measured simultaneously and consecutively with an automatic oscillometric device, in two visits. The IAD of the simultaneous SBP was significantly lower compared to the consecutive one, both in the first (3.51<!--> <!-->±<!--> <!-->4.1 vs. 4.40<!--> <!-->±<!--> <!-->3.7<!--> <!-->mmHg; <em>P</em> <!--><<!--> <!-->.01) and in the second visit (3.62<!--> <!-->±<!--> <!-->3.5 vs. 5.69<!--> <!-->±<!--> <!-->5.1<!--> <!-->mmHg; <em>P</em> <!--><<!--> <!-->.001). When the IAD of SBP was categorized as ≥<!--> <!-->10 or <<!--> <!-->10<!--> <!-->mmHg, the reproducibility between visits was insignificant in both simultaneous measurements and consecutive measurements. The frequency of initial dominance was similar between the left and right arm in simultaneous ones (46.2 vs. 43.3%), and greater in the right arm in consecutive ones (55.2 vs. 38.5). The persistence of dominance between both visits was significantly higher when SBP was measured simultaneously (54.4% vs. 45.5%; <em>P</em> <!--><<!--> <!-->.01). Our study shows that to define the arm with the highest BP, simultaneous measurements are preferable. In treated and controlled hypertensive patients, the poor persistence of initial dominance between visits requires us to review the recommendation of recording, during follow-up, the BP in the arm where it was highest on the first visit.</div></div>","PeriodicalId":39403,"journal":{"name":"Hipertension y Riesgo Vascular","volume":"41 4","pages":"Pages 232-239"},"PeriodicalIF":1.2,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141752973","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-10-01DOI: 10.1016/j.hipert.2024.04.006
M.J. Vallejo Herrera , V. Vallejo Herrera , V. Márquez Pérez , F. Serrano Puche , I. Vegas Vegas
Pheochromocytomas are rare neuroendocrine tumors that can present as hypertensive crises or serious cardiac and cerebrovascular complications that endanger the patient's life.
Two unusual cases of adrenergic crises induced by pheochromocytoma with cardiovascular manifestations are presented, one with multiple complications/multiorgan failure, fatal outcome and definitive diagnosis in the post mortem autopsy, and another with a satisfactory evolution after diagnosis and appropriate treatment.
{"title":"Feocromocitoma como simulador de patología cardiaca","authors":"M.J. Vallejo Herrera , V. Vallejo Herrera , V. Márquez Pérez , F. Serrano Puche , I. Vegas Vegas","doi":"10.1016/j.hipert.2024.04.006","DOIUrl":"10.1016/j.hipert.2024.04.006","url":null,"abstract":"<div><div>Pheochromocytomas are rare neuroendocrine tumors that can present as hypertensive crises or serious cardiac and cerebrovascular complications that endanger the patient's life.</div><div>Two unusual cases of adrenergic crises induced by pheochromocytoma with cardiovascular manifestations are presented, one with multiple complications/multiorgan failure, fatal outcome and definitive diagnosis in the <em>post mortem</em> autopsy, and another with a satisfactory evolution after diagnosis and appropriate treatment.</div></div>","PeriodicalId":39403,"journal":{"name":"Hipertension y Riesgo Vascular","volume":"41 4","pages":"Pages 260-263"},"PeriodicalIF":1.2,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141077099","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-10-01DOI: 10.1016/j.hipert.2024.07.002
{"title":"Calor nocturno e incidencia de ictus","authors":"","doi":"10.1016/j.hipert.2024.07.002","DOIUrl":"10.1016/j.hipert.2024.07.002","url":null,"abstract":"","PeriodicalId":39403,"journal":{"name":"Hipertension y Riesgo Vascular","volume":"41 4","pages":"Pages 268-269"},"PeriodicalIF":1.2,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142663013","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-10-01DOI: 10.1016/j.hipert.2024.07.001
C. Alvarez , L. Peñailillo , P. Ibacache-Saavedra , D. Jerez-Mayorga , C. Campos-Jara , D.C. Andrade , G.V. Guimarães , E. Gomes-Ciolac , P. Delgado-Floody , M. Izquierdo , A.N. Gurovich
Background
This study aimed to examine the effects of a six-week of concurrent training using high-intensity interval plus resistance training on flow-mediated dilation and pulse wave velocity in hypertensive, elevated blood pressure, or normotensive. A secondary goal was to analyze the inter-individual variability.
Methods
A randomized controlled clinical trial was executed with 60 adult participants distributed across six groups: three control groups of hypertensive, elevated blood pressure, or normotensive and other three experimental hypertensive, elevated blood pressure, and normotensive groups, each comprising n = 10 individuals. Participants underwent a six-week intervention of concurrent exercise using high-intensity interval plus resistance training three-weekly. Flow mediated dilation and pulse wave velocity and secondary vascular assessments were conducted before and after the intervention.
Results
The hypertensive exercise group exhibited a significant increase in flow mediated dilation (Δ+7.7%; p = 0.003) and a reduction in pulse wave velocity (Δ−1.2 m s−1; p < 0.0001). The normotensive exercise group also showed a significant increase in flow mediated dilation (Δ+8.4%, p = 0.002).
Conclusion
The six-week concurrent exercise using high-intensity interval plus resistance training protocol, characterized by its clinical time-efficiency, was effective in improving endothelial function, as demonstrated by increased flow mediated dilation, and in reducing arterial stiffness, indicated by decreased pulse wave velocity.
{"title":"Six weeks of a concurrent training therapy improves endothelial function and arterial stiffness in hypertensive adults with minimum non-responders","authors":"C. Alvarez , L. Peñailillo , P. Ibacache-Saavedra , D. Jerez-Mayorga , C. Campos-Jara , D.C. Andrade , G.V. Guimarães , E. Gomes-Ciolac , P. Delgado-Floody , M. Izquierdo , A.N. Gurovich","doi":"10.1016/j.hipert.2024.07.001","DOIUrl":"10.1016/j.hipert.2024.07.001","url":null,"abstract":"<div><h3>Background</h3><div>This study aimed to examine the effects of a six-week of concurrent training using high-intensity interval plus resistance training on flow-mediated dilation and pulse wave velocity in hypertensive, elevated blood pressure, or normotensive. A secondary goal was to analyze the inter-individual variability.</div></div><div><h3>Methods</h3><div>A randomized controlled clinical trial was executed with 60 adult participants distributed across six groups: three control groups of hypertensive, elevated blood pressure, or normotensive and other three experimental hypertensive, elevated blood pressure, and normotensive groups, each comprising <em>n</em> <!-->=<!--> <!-->10 individuals. Participants underwent a six-week intervention of concurrent exercise using high-intensity interval plus resistance training three-weekly. Flow mediated dilation and pulse wave velocity and secondary vascular assessments were conducted before and after the intervention.</div></div><div><h3>Results</h3><div>The hypertensive exercise group exhibited a significant increase in flow mediated dilation (<em>Δ</em>+7.7%; <em>p</em> <!-->=<!--> <!-->0.003) and a reduction in pulse wave velocity (<em>Δ</em>−1.2<!--> <!-->m<!--> <!-->s<sup>−1</sup>; <em>p</em> <!--><<!--> <!-->0.0001). The normotensive exercise group also showed a significant increase in flow mediated dilation (<em>Δ</em>+8.4%, <em>p</em> <!-->=<!--> <!-->0.002).</div></div><div><h3>Conclusion</h3><div>The six-week concurrent exercise using high-intensity interval plus resistance training protocol, characterized by its clinical time-efficiency, was effective in improving endothelial function, as demonstrated by increased flow mediated dilation, and in reducing arterial stiffness, indicated by decreased pulse wave velocity.</div></div>","PeriodicalId":39403,"journal":{"name":"Hipertension y Riesgo Vascular","volume":"41 4","pages":"Pages 240-250"},"PeriodicalIF":1.2,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141856722","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-10-01DOI: 10.1016/j.hipert.2024.05.003
A. Dutta , V. Chaudhary , A.K. Gupta , K. Murti , S. Kumari , D. Dhir , S. Meenakshi , C. Ahuja , B. Sharma , B. Pal
Background
Hypertension is a prevalent health challenge in India, with a bidirectional link to depression. Recognizing the prevalence of depression among hypertensive patients and associated factors are important for better health outcomes.
Methods
A comprehensive search was conducted in PubMed, Embase, Scopus, and Google Scholar databases to identify relevant studies. R software was used for analysis, employing a random effects model with a 95% confidence interval. Subgroup analyses were done to explore sources of heterogeneity within the included studies.
Results
The prevalence of depression among hypertensive patients in India was 39.8% (95% CI: 28.6; 52.1). Despite a higher prevalence observed in South region (44.7%) compared to North (26.9%), the difference was not significant (p = 0.39). Studies utilizing different assessment scales and varying sample sizes yielded similar prevalence. However, a temporal trend analysis indicated a higher prevalence in studies published between 2020 and 2023 (52.6%) compared to those published between 2016 and 2019 (35.5%) (p = 0.03). Major factors associated with depression included lower socioeconomic status, low education level, female gender, uncontrolled hypertension, and COVID-19 related factors.
Conclusions
A significant proportion of hypertensive patients suffer from depression. Therefore, screening for depression in hypertensive patients is essential to improve hypertension management in India.
背景：高血压是印度普遍存在的健康问题，与抑郁症有双向联系。认识高血压患者中抑郁症的发病率及相关因素对于改善健康状况非常重要：在 PubMed、Embase、Scopus 和 Google Scholar 数据库中进行了全面搜索，以确定相关研究。使用 R 软件进行分析，采用随机效应模型，置信区间为 95%。对纳入的研究进行了分组分析，以探讨异质性的来源：印度高血压患者的抑郁症患病率为 39.8%（95% CI：28.6；52.1）。尽管南部地区的患病率（44.7%）高于北部地区（26.9%），但差异并不显著（P=0.39）。采用不同评估量表和不同样本量的研究得出了相似的患病率。然而，时间趋势分析表明，2020 年至 2023 年间发表的研究（52.6%）的患病率高于 2016 年至 2019 年间发表的研究（35.5%）（P=0.03）。与抑郁症相关的主要因素包括较低的社会经济地位、低教育水平、女性性别、未控制的高血压以及COVID-19相关因素：结论：相当一部分高血压患者患有抑郁症。因此，对高血压患者进行抑郁症筛查对于改善印度的高血压管理至关重要。
{"title":"Prevalence of depression in hypertensive patients and its associated factors in India: A systematic review and meta-analysis","authors":"A. Dutta , V. Chaudhary , A.K. Gupta , K. Murti , S. Kumari , D. Dhir , S. Meenakshi , C. Ahuja , B. Sharma , B. Pal","doi":"10.1016/j.hipert.2024.05.003","DOIUrl":"10.1016/j.hipert.2024.05.003","url":null,"abstract":"<div><h3>Background</h3><div>Hypertension is a prevalent health challenge in India, with a bidirectional link to depression. Recognizing the prevalence of depression among hypertensive patients and associated factors are important for better health outcomes.</div></div><div><h3>Methods</h3><div>A comprehensive search was conducted in PubMed, Embase<span>, Scopus, and Google Scholar databases to identify relevant studies. R software was used for analysis, employing a random effects model with a 95% confidence interval. Subgroup analyses were done to explore sources of heterogeneity within the included studies.</span></div></div><div><h3>Results</h3><div>The prevalence of depression among hypertensive patients in India was 39.8% (95% CI: 28.6; 52.1). Despite a higher prevalence observed in South region (44.7%) compared to North (26.9%), the difference was not significant (<em>p</em> <!-->=<!--> <!-->0.39). Studies utilizing different assessment scales and varying sample sizes yielded similar prevalence. However, a temporal trend analysis indicated a higher prevalence in studies published between 2020 and 2023 (52.6%) compared to those published between 2016 and 2019 (35.5%) (<em>p</em> <!-->=<!--> <!-->0.03). Major factors associated with depression included lower socioeconomic status, low education level, female gender, uncontrolled hypertension, and COVID-19 related factors.</div></div><div><h3>Conclusions</h3><div>A significant proportion of hypertensive patients suffer from depression. Therefore, screening for depression in hypertensive patients is essential to improve hypertension management in India.</div></div>","PeriodicalId":39403,"journal":{"name":"Hipertension y Riesgo Vascular","volume":"41 4","pages":"Pages 217-225"},"PeriodicalIF":1.2,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141499196","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-10-01DOI: 10.1016/j.hipert.2024.06.002
C. Álvarez-González , J. Espíldora-Hernández , M.A. Sánchez-Chaparro
In celiac disease (CD) there is a state of hypercoagulability and multiple factors have been found that may be involved. Cases of association of CD and antiphospholipid síndrome (APS) have been described and several observational studies have found an increase in antiphospolipid antibodies (AAF) in patients with CD, so both entities may be interrelated, increasing the risk of thrombotic events. A descriptive case of a patient who is simultaneusly diagnosed with CD and APS is presented.
乳糜泻（CD）患者会出现高凝状态，已发现可能与多种因素有关。CD 和抗磷脂综合征（APS）相关的病例已有描述，一些观察性研究发现 CD 患者体内抗磷脂抗体（AAF）增加，因此这两种疾病可能相互关联，增加了血栓事件的风险。本报告描述了一例同时被诊断为 CD 和 APS 的患者。
{"title":"Más allá de la hipercoagulabilidad en la enfermedad celíaca","authors":"C. Álvarez-González , J. Espíldora-Hernández , M.A. Sánchez-Chaparro","doi":"10.1016/j.hipert.2024.06.002","DOIUrl":"10.1016/j.hipert.2024.06.002","url":null,"abstract":"<div><div>In celiac disease (CD) there is a state of hypercoagulability and multiple factors have been found that may be involved. Cases of association of CD and antiphospholipid síndrome (APS) have been described and several observational studies have found an increase in antiphospolipid antibodies (AAF) in patients with CD, so both entities may be interrelated, increasing the risk of thrombotic events. A descriptive case of a patient who is simultaneusly diagnosed with CD and APS is presented.</div></div>","PeriodicalId":39403,"journal":{"name":"Hipertension y Riesgo Vascular","volume":"41 4","pages":"Pages 264-267"},"PeriodicalIF":1.2,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141564773","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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