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[Influence of cardiorespiratory training program on the intercellular adhesion molecule level in patients with postmastectomy syndrome]. [心肺训练计划对乳房切除术后综合征患者细胞间粘附分子水平的影响]。
Q4 Medicine Pub Date : 2024-01-01 DOI: 10.17116/kurort202410104145
V V Krasnikova, O V Fionik, M L Pospelova, N S Trofimov, T A Zhorova, A E Nikolaeva, S N Tonyan, A M Makhanova, K A Samochernykh, A O Konradi, M S Voinov, M V Vagaitseva, E A Demchenko

Postmastectomy syndrome (PMS) is a complex neurovascular set of symptoms that develops in most patients after breast cancer (BC) treatment and significantly reduces the quality of life. One of the potential mechanisms of its occurrence is considered to be an endothelial dysfunction. The possible method of reducing manifestation of endothelial dysfunction is systematic aerobic dynamic training.

Objective: To evaluate the influence of 12-week aerobic dynamic training program of moderate intensity on the endothelial dysfunction laboratory markers and life quality in patients with PMS.

Material and methods: Single-center prospective randomized trial included 40 patients with PMS divided into study (20 patients) and comparative (20 patients) groups, as well as 20 healthy female volunteers. The expression level of soluble intercellular adhesion molecule-1 (ICAM-1) and platelet endothelial cell adhesion molecule-1 (PECAM-1) were evaluated in all participants at baseline by enzyme-linked immunosorbent assay method, and additionally psychological and physical component of health by SF-36 questionnaire were assessed in patients with PMS.

Patients of study group received a course of 12-week partially controlled aerobic dynamic training of moderate intensity lasting 45 minutes with frequency equal 5 times per week. Patients with PMS were re-evaluated for ICAM-1 and PECAM-1, as well as for life quality.

Results: The group of patients with PMS after BC treatment had increased level of ICAM-1 in long-term period, that may indicate endothelial dysfunction. Statistically significant decrease of endothelial dysfunction laboratory markers was revealed in patients with PMS, who underwent the course of cardiorespiratory training. In the same time, the dynamics of changes in ICAM-1 was higher in the study group than in comparative group. Further, improvement of physical and psychological components of health by SF-36 questionnaire was found.

Conclusions: The program of cardiorespiratory trainings of moderate intensity in patients, who had BC treatment a year ago, decreases intercellular adhesion molecules level that may show an improvement of endothelial dysfunction.

乳腺癌切除术后综合征(PMS)是一种复杂的神经血管症状,大多数患者在接受乳腺癌(BC)治疗后都会出现这种症状,严重降低了患者的生活质量。其发生的潜在机制之一被认为是内皮功能障碍。减少内皮功能障碍表现的可能方法是系统的有氧动态训练:评估为期12周的中等强度有氧动态训练项目对经前期综合征患者内皮功能障碍实验室指标和生活质量的影响:单中心前瞻性随机试验纳入了40名经前期综合征患者,分为研究组(20名)和对比组(20名),以及20名健康女性志愿者。研究组患者接受为期 12 周的部分控制有氧动态训练,训练强度适中,持续时间为 45 分钟,每周 5 次。对经前期综合征患者的 ICAM-1 和 PECAM-1 以及生活质量进行了重新评估:结果:经前期综合征患者在接受 BC 治疗后,ICAM-1 水平长期升高,这可能预示着内皮功能障碍。据统计,接受心肺训练的 PMS 患者的内皮功能障碍实验室指标明显下降。同时,研究组 ICAM-1 的动态变化高于对比组。此外,根据 SF-36 问卷调查,研究组的身体和心理健康水平也有所提高:结论:对一年前接受过 BC 治疗的患者进行中等强度的心肺训练可降低细胞间粘附分子的水平,从而改善内皮功能障碍。
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引用次数: 0
[Systemic mechanisms of premature aging and their correction by complex physiotherapy application].
Q4 Medicine Pub Date : 2024-01-01 DOI: 10.17116/kurort202410106260
N B Korchazhkina, A A Mikhailova, K V Kotenko, S N Nagornyev, V K Frolkov, A V Badimova, I V Reshetova
<p><p>Rationale: Human aging is accompanied by various somatic diseases that increase the biological age and reduce the period of active longevity. For the development of effective methods of premature aging prevention it is necessary to expand the search of predictors of forming pathological reactions, their system analysis and selection of the factors of influence capable to activate the processes of sanogenesis.</p><p><strong>Objective: </strong>System analysis of pathological changes in various functional systems of the organism, formed in the process of ontogenesis, and evaluation of the effectiveness of the preventive potential of polymodal physiotherapy in terms of preserving the level of health in elderly patients.</p><p><strong>Material and methods: </strong>The studies were conducted on the basis of the Scientific and Clinical Center 1 of the Russian National Cancer Center named after Acad. B.V. Petrovsky with the participation of 80 patients (46 men and 34 women) aged from 20 to 90 years. After signing a voluntary informed consent for a special study with the processing of their personal data, all patients underwent a comprehensive clinical, laboratory and functional examination. Patients were divided into two groups by simple fixed randomization method. The comparison group (<i>n</i>=40) received moderate physical activity, reduced caloric intake and vitamin therapy. Patients of the main group (<i>n</i>=40) additionally received physiotherapeutic complex, which included multimodal influences using Alpha LED Ohu Light-Spa apparatus, hyper-hypoxitherapy, pressotherapy, dry carbon dioxide baths. Preventive courses were repeated twice with an interval of 6 months. All studies were performed before and 6 months after the completion of the preventive course.</p><p><strong>Results: </strong>In the process of aging, disorders develop in various systems of the human body, which leads to an increase in biological age and aging rate, while in women these processes are formed more slowly. Pathological reactions in elderly patients were characterized by disturbances in carbohydrate and lipid metabolism, activation of pro- oxidant and inflammatory reactions, smaller relative telomere sizes. It has been established that the problems preventing active and healthy longevity are formed early enough and preventive measures should be started at a young and early adulthood. In patients of the comparison group, the twofold application of the preventive course had no noticeable favorable effect, moreover, the severity of lipid metabolism disorders even increased. Additional to standard recommendations application of a complex of physiotherapeutic procedures had a pronounced prophylactic effect, which was manifested in reduction of biological age, optimization of carbohydrate and lipid metabolism, reduction of activity of inflammatory reactions.</p><p><strong>Conclusion: </strong>The leading role of metabolic reactions disorders, which are based on insulin r
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引用次数: 0
[The effectiveness of wellness programs in correcting risk factors for atherosclerosis in a sanatorium].
Q4 Medicine Pub Date : 2024-01-01 DOI: 10.17116/kurort2024101062102
L T Gilmutdinova, A M Ivanov, B R Gilmutdinov, R R Kudayarova, E N Galimulina, A R Gilmutdinov, V E Illarionov, E R Faizova
<p><p>Atherosclerosis is the main cause of mortality and disability in the adult population. One of the reasons for the high mortality from atherosclerosis is the lack of effective measures to prevent cardiovascular complications that ensure timely detection and correction of risk factors for the development of atherosclerosis, primarily lipid metabolism disorders with high values of proatherogenic lipids. In the restorative correction of dyslipidemia, the most promising is the use of health programs based on therapeutic physical factors, the combined use of natural (mineral waters, kumiss, climate) with physical training, training in health schools, with their implementation in sanatorium-resort conditions.</p><p><strong>Objective: </strong>Development and evaluation of the effectiveness of health programs of varying intensity based on therapeutic physical factors in the correction of risk factors for the development of atherosclerosis in a sanatorium.</p><p><strong>Material and methods: </strong>The study included 75 men aged 38 to 48 years with risk factors for atherosclerosis and atherogenic cardiovascular diseases. In compliance with the principles of randomization, the patients were divided into groups. The health program for the 1st group (<i>n</i>=25) included drinking mineral water, kumiss from mare's milk, a hypolipidemic diet with limited animal fats, terrain cure, therapeutic exercises, and climatotherapy. The health program for patients in the 2nd group (<i>n</i>=25) in addition to the program for the 1st group included hydrogen sulphide baths and Nordic walking, with further continuation for 3 months. For patients in the 3rd group (<i>n</i>=25), the health program included, in addition to the program for the 2nd group, physical training on an exercise bike, with further continuation for 3 months.</p><p><strong>Results: </strong>The effectiveness of the health program is most pronounced in patients of the 3rd group: after the course of health improvement in the sanatorium, an improvement in the blood lipid profile is noted with a decrease in the level of total cholesterol by 8.22% (<i>p</i><0.05), triglycerides by 7.61% (<i>p</i><0.05), low-density lipoprotein cholesterol by 9.94% (<i>p</i><0.05), an increase in high-density lipoprotein cholesterol by 6.66% (<i>p</i><0.05) from the initial values. Improvement of peroxide metabolism and antioxidant system with decrease of malonic dialdehyde, catalase and superoxide dismutase activity was revealed. Against the background of prolongation of physical training for 3 months, enhancement of hypolipidemic and antioxidant effects with increase of physical performance and adaptation potential was noted.</p><p><strong>Conclusion: </strong>To correct risk factors for the development of atherosclerosis and atherogenic cardiovascular diseases, it is advisable to use health programs based on therapeutic physical factors: drinking mineral water, kumiss, therapeutic gymnastics, climatotherapy, hydrog
{"title":"[The effectiveness of wellness programs in correcting risk factors for atherosclerosis in a sanatorium].","authors":"L T Gilmutdinova, A M Ivanov, B R Gilmutdinov, R R Kudayarova, E N Galimulina, A R Gilmutdinov, V E Illarionov, E R Faizova","doi":"10.17116/kurort2024101062102","DOIUrl":"https://doi.org/10.17116/kurort2024101062102","url":null,"abstract":"&lt;p&gt;&lt;p&gt;Atherosclerosis is the main cause of mortality and disability in the adult population. One of the reasons for the high mortality from atherosclerosis is the lack of effective measures to prevent cardiovascular complications that ensure timely detection and correction of risk factors for the development of atherosclerosis, primarily lipid metabolism disorders with high values of proatherogenic lipids. In the restorative correction of dyslipidemia, the most promising is the use of health programs based on therapeutic physical factors, the combined use of natural (mineral waters, kumiss, climate) with physical training, training in health schools, with their implementation in sanatorium-resort conditions.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Objective: &lt;/strong&gt;Development and evaluation of the effectiveness of health programs of varying intensity based on therapeutic physical factors in the correction of risk factors for the development of atherosclerosis in a sanatorium.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Material and methods: &lt;/strong&gt;The study included 75 men aged 38 to 48 years with risk factors for atherosclerosis and atherogenic cardiovascular diseases. In compliance with the principles of randomization, the patients were divided into groups. The health program for the 1st group (&lt;i&gt;n&lt;/i&gt;=25) included drinking mineral water, kumiss from mare's milk, a hypolipidemic diet with limited animal fats, terrain cure, therapeutic exercises, and climatotherapy. The health program for patients in the 2nd group (&lt;i&gt;n&lt;/i&gt;=25) in addition to the program for the 1st group included hydrogen sulphide baths and Nordic walking, with further continuation for 3 months. For patients in the 3rd group (&lt;i&gt;n&lt;/i&gt;=25), the health program included, in addition to the program for the 2nd group, physical training on an exercise bike, with further continuation for 3 months.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;The effectiveness of the health program is most pronounced in patients of the 3rd group: after the course of health improvement in the sanatorium, an improvement in the blood lipid profile is noted with a decrease in the level of total cholesterol by 8.22% (&lt;i&gt;p&lt;/i&gt;&lt;0.05), triglycerides by 7.61% (&lt;i&gt;p&lt;/i&gt;&lt;0.05), low-density lipoprotein cholesterol by 9.94% (&lt;i&gt;p&lt;/i&gt;&lt;0.05), an increase in high-density lipoprotein cholesterol by 6.66% (&lt;i&gt;p&lt;/i&gt;&lt;0.05) from the initial values. Improvement of peroxide metabolism and antioxidant system with decrease of malonic dialdehyde, catalase and superoxide dismutase activity was revealed. Against the background of prolongation of physical training for 3 months, enhancement of hypolipidemic and antioxidant effects with increase of physical performance and adaptation potential was noted.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusion: &lt;/strong&gt;To correct risk factors for the development of atherosclerosis and atherogenic cardiovascular diseases, it is advisable to use health programs based on therapeutic physical factors: drinking mineral water, kumiss, therapeutic gymnastics, climatotherapy, hydrog","PeriodicalId":39492,"journal":{"name":"Voprosy kurortologii, fizioterapii, i lechebnoi fizicheskoi kultury","volume":"101 6. Vyp. 2","pages":"102-109"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143068430","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[The influence of neurofeedback on the β-rhythm of the brain on the characteristics of attention in athletes with different training orientations].
Q4 Medicine Pub Date : 2024-01-01 DOI: 10.17116/kurort202410106220
N V Lunina, Yu V Koryagina, V S Nopina, K O Iosipchuk, M H Tishkova, V E Illarionov, Z M Gazaeva

Modern scientific research has shown that neurofeedback optimizes the functioning of the nervous system as a whole, increases the efficiency and productivity of various types of activities. In clinical practice, neurofeedback based on the β-rhythm of the brain has been effective in correcting conditions associated with decreased attention, promoting concentration and behavioral improvements. However, the influence of neurofeedback on the β-rhythm of the brain on the attention processes of athletes with different training orientations has not yet been sufficiently studied.

Objective: Studying the effect of neurofeedback on the β-rhythm of the brain on the characteristics of attention in athletes with different training orientations.

Material and methods: The study involved male athletes aged 18-22 years old, divided into 5 groups by sport and a comparison group. The course of neurofeedback on the β-rhythm of the brain consisted of 10 sessions, including graphic and game sessions, in which it was necessary to select a strategy for raising the β-rhythm of the brain during muscle relaxation, implemented under conditions of visual and auditory biofeedback. The characteristics of attention were studied using the Schulte method.

Results: The initial values of the studied characteristics of attention in the comparison group (CG) did not have reliably significant differences with similar indicators in the studied groups of athletes with different training orientations. Analysis of the dynamics of attention indicators in the GS showed a tendency, without significant changes, to improve the efficiency of attention (EA) and the total time of work in the test. A course of neurofeedback based on the β-rhythm of the brain contributed to the improvement of attention characteristics in athletes, depending on the direction of the training process. EA increased to a high level in young men of cyclic, game, complex-coordination sports and among martial artists, and in athletes of speed-strength sports - to a level above average. Athletes of all studied groups who completed the course of β-training increased the speed of development with consistently high values in representatives of cyclic sports, in almost all groups the stability of attention increased to a high level (p≤0.05), with the best values in the coordination sports, among team sports athletes the indicator reached an average level.

Conclusion: Optimization of attention characteristics when using neurofeedback according to the β-rhythm of the brain in athletes is specific depending on the direction of the training process, and in total leads to a significant improvement in the studied indicators.

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引用次数: 0
[The long-term observation period of pregnant women after acute gestational pyelonephritis].
Q4 Medicine Pub Date : 2024-01-01 DOI: 10.17116/kurort202410106233
A A Fedorov, M R Gaitova, M A Franc, E V Telegina, E V Dzyubinskaya, N V Efimenko, E N Chalaya, E N Zhumanova, V V Moiseev

Urinary tract infections, in particular acute gestational pyelonephritis (AGP) determine a high risk of developing various complications of pregnancy and childbirth. The development of new medical technologies for the treatment of AGP remains relevant. It has not only high direct effectiveness, but also shows a distinct impact of secondary prevention of pyelonephritis exacerbations and a fetoprotective effect. An objective evidence for these effects is the study of long-term treatment outcomes.

Objective: To evaluate the general condition of pregnant women in a randomized controlled study of the long-term observation period who underwent acute gestational pyelonephritis, birth results, quality of life of the patients and vitality of the newborns.

Material and methods: The study included 93 women at the age of 16 to 40 years old who underwent AGP. They were divided into two groups by simple randomization: the main/MG (46 people) and the control/CG (47 people). The control group of the patients was prescribed the drug standard; the main one had intravenous ozone therapy (OT) in addition to it.

Results: In the MG the patients had significant differences (p<0.05-0.001) with women of the CG in such indicators as: repeated relapses of gestational pyelonephritis (4.5 times), late gestational toxicosis (2.6 times), the number of newborns with normal growth and weight parameters (1.9 times), bacteriuria (3.0 times), leukocytouria (4.0 times), medical care for the main disease (5.0 times), outpatient treatment (8.0 times) and quality of life indicators - physical and social activity as well as general health.

Conclusion: An additional prescription in the standard of care for patients with AGP based on intravenous administration of an ozone-oxygen mixture significantly improves the long-term results of the therapy and the quality of life of patients who have undergone AGP, and also has a distinct fetoprotective effect. The absence of adverse reactions with all the patients including in the long-term follow-up period indicates the safety of a new complex of restorative treatment for AGP.

{"title":"[The long-term observation period of pregnant women after acute gestational pyelonephritis].","authors":"A A Fedorov, M R Gaitova, M A Franc, E V Telegina, E V Dzyubinskaya, N V Efimenko, E N Chalaya, E N Zhumanova, V V Moiseev","doi":"10.17116/kurort202410106233","DOIUrl":"https://doi.org/10.17116/kurort202410106233","url":null,"abstract":"<p><p>Urinary tract infections, in particular acute gestational pyelonephritis (AGP) determine a high risk of developing various complications of pregnancy and childbirth. The development of new medical technologies for the treatment of AGP remains relevant. It has not only high direct effectiveness, but also shows a distinct impact of secondary prevention of pyelonephritis exacerbations and a fetoprotective effect. An objective evidence for these effects is the study of long-term treatment outcomes.</p><p><strong>Objective: </strong>To evaluate the general condition of pregnant women in a randomized controlled study of the long-term observation period who underwent acute gestational pyelonephritis, birth results, quality of life of the patients and vitality of the newborns.</p><p><strong>Material and methods: </strong>The study included 93 women at the age of 16 to 40 years old who underwent AGP. They were divided into two groups by simple randomization: the main/MG (46 people) and the control/CG (47 people). The control group of the patients was prescribed the drug standard; the main one had intravenous ozone therapy (OT) in addition to it.</p><p><strong>Results: </strong>In the MG the patients had significant differences (<i>p</i><0.05-0.001) with women of the CG in such indicators as: repeated relapses of gestational pyelonephritis (4.5 times), late gestational toxicosis (2.6 times), the number of newborns with normal growth and weight parameters (1.9 times), bacteriuria (3.0 times), leukocytouria (4.0 times), medical care for the main disease (5.0 times), outpatient treatment (8.0 times) and quality of life indicators - physical and social activity as well as general health.</p><p><strong>Conclusion: </strong>An additional prescription in the standard of care for patients with AGP based on intravenous administration of an ozone-oxygen mixture significantly improves the long-term results of the therapy and the quality of life of patients who have undergone AGP, and also has a distinct fetoprotective effect. The absence of adverse reactions with all the patients including in the long-term follow-up period indicates the safety of a new complex of restorative treatment for AGP.</p>","PeriodicalId":39492,"journal":{"name":"Voprosy kurortologii, fizioterapii, i lechebnoi fizicheskoi kultury","volume":"101 6. Vyp. 2","pages":"33-39"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143068441","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Electromagnetic stimulation in diaphragm dysfunction: repetitive peripheral magnetic stimulation as a method of choice during the rehabilitation period after stroke. (Literature review)]. [电磁刺激治疗膈肌功能障碍:重复性外周磁刺激是中风后康复期的首选方法。(文献综述)]。
Q4 Medicine Pub Date : 2024-01-01 DOI: 10.17116/kurort202410105157
E Yu Starkova, N N Vladimirova, E M Tsvetkova, V Yu Litau, E A Melnikova
<p><p>Diaphragm dysfunction develops in central nervous system damage, chest injuries, complications of cardiac surgery, long-term artificial lung ventilation, respiratory diseases. Anatomical morphological features of phrenic nerves allow to effectively use electromagnetic stimulation methods for functional recovery of the diaphragm in different pathological conditions. Invasive and non-invasive, electric and magnetic methods of stimulation are used depending on the severity of manifestations of the diaphragm dysfunction and its genesis.</p><p><strong>Objective: </strong>To perform a review and comparison of modern methods of electromagnetic stimulation of the diaphragm; to determine the role of repetitive peripheral magnetic stimulation (rPMS) in the diaphragm dysfunction as a result of stroke.</p><p><strong>Material and methods: </strong>An analysis of publications from the Pubmed and Elibrary databases for 2008-2024 years was conducted. The search was done by the following keywords: diaphragm dysfunction, repetitive peripheral magnetic stimulation of phrenic nerve, stroke, hemiparesis.</p><p><strong>Results: </strong>There is a real possibility of effective diaphragm stimulation for recovery of its function due to the innervation of the diaphragm strictly by the phrenic nerves, their large diameter, presence of myelinated fibers as well as anatomical location of the phrenic nerves. Direct electric stimulation of the phrenic nerve is usually applied in the case of long-term continuous support of respiratory function. Non-invasive techniques of electric or magnetic stimulation of the phrenic nerve or directly of the diaphragmatic muscle are used in the case of temporary respiratory support or recovery of diaphragm function. The motor neurons of the brain and peripheral nerves are activated, thus a peak strength of the variable magnetic field usually reachs 1-2 T in rPMS. Application of rPMS affects the efferent nerve fibers, causing muscle contractions, and activates sensory afferent fibers, creating a stimulating effect on the superjacent nervous structures. It is advisable to use rPMS of the phrenic nerve in the cervical segment or rPMS of one of the segments of the diaphragmatic muscle in the case of unilateral diaphragm lesion during the recovery period after stroke. It is important to consider the frequency of exposure in the 10-30 Hz range, the closest location of the coil to the stimulation area, the choice of the coil shape depending on the localization when adjusting parameters of rPMS.</p><p><strong>Conclusion: </strong>The use of rPMS of the phrenic nerve and diaphragm allows to preserve and recover motor and contractile functions of the diaphragm in different pathological conditions, including its unilateral lesion as a result of stroke. The method of rPMS of the phrenic nerves has a number of advantages over electric stimulation and repetitive transcranial magnetic stimulation, since it allows to achieve an effective motor response
中枢神经系统损伤、胸部损伤、心脏手术并发症、长期人工肺通气、呼吸系统疾病都会导致膈肌功能障碍。膈神经的解剖形态特征允许在不同病理条件下有效使用电磁刺激方法恢复膈肌功能。根据膈肌功能障碍表现的严重程度及其成因,可使用有创和无创、电刺激和磁刺激方法:对膈肌电磁刺激的现代方法进行回顾和比较;确定重复性外周磁刺激(rPMS)在中风导致的膈肌功能障碍中的作用:对 Pubmed 和 Elibrary 数据库中 2008-2024 年的出版物进行了分析。搜索关键词如下:膈肌功能障碍、膈神经重复外周磁刺激、中风、偏瘫:由于膈神经严格支配膈肌、膈神经直径大、有髓鞘纤维的存在以及膈神经的解剖位置,因此确实存在有效刺激膈肌以恢复其功能的可能性。对膈神经的直接电刺激通常用于长期持续支持呼吸功能的情况。对膈神经或直接对膈肌进行电刺激或磁刺激的非侵入性技术则用于暂时支持呼吸或恢复膈肌功能。大脑和外周神经的运动神经元被激活,因此在 rPMS 中,可变磁场的峰值强度通常达到 1-2 T。应用 rPMS 会影响传出神经纤维,引起肌肉收缩,并激活感觉传入纤维,对上邻神经结构产生刺激作用。建议在脑卒中后的恢复期使用颈段膈神经的 rPMS 或在单侧膈肌病变的情况下使用膈肌一个节段的 rPMS。在调整 rPMS 的参数时,必须考虑 10-30 Hz 范围内的暴露频率、线圈与刺激区域的最近位置以及根据定位情况选择线圈形状:结论:对膈神经和膈肌进行 rPMS 可在不同病理情况下保护和恢复膈肌的运动和收缩功能,包括中风导致的膈肌单侧病变。与电刺激和重复经颅磁刺激相比,膈神经 rPMS 方法有许多优点,因为它可以在较小的暴露强度下实现有效的运动反应,而且无痛、非接触,患者的耐受性更好。
{"title":"[Electromagnetic stimulation in diaphragm dysfunction: repetitive peripheral magnetic stimulation as a method of choice during the rehabilitation period after stroke. (Literature review)].","authors":"E Yu Starkova, N N Vladimirova, E M Tsvetkova, V Yu Litau, E A Melnikova","doi":"10.17116/kurort202410105157","DOIUrl":"https://doi.org/10.17116/kurort202410105157","url":null,"abstract":"&lt;p&gt;&lt;p&gt;Diaphragm dysfunction develops in central nervous system damage, chest injuries, complications of cardiac surgery, long-term artificial lung ventilation, respiratory diseases. Anatomical morphological features of phrenic nerves allow to effectively use electromagnetic stimulation methods for functional recovery of the diaphragm in different pathological conditions. Invasive and non-invasive, electric and magnetic methods of stimulation are used depending on the severity of manifestations of the diaphragm dysfunction and its genesis.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Objective: &lt;/strong&gt;To perform a review and comparison of modern methods of electromagnetic stimulation of the diaphragm; to determine the role of repetitive peripheral magnetic stimulation (rPMS) in the diaphragm dysfunction as a result of stroke.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Material and methods: &lt;/strong&gt;An analysis of publications from the Pubmed and Elibrary databases for 2008-2024 years was conducted. The search was done by the following keywords: diaphragm dysfunction, repetitive peripheral magnetic stimulation of phrenic nerve, stroke, hemiparesis.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;There is a real possibility of effective diaphragm stimulation for recovery of its function due to the innervation of the diaphragm strictly by the phrenic nerves, their large diameter, presence of myelinated fibers as well as anatomical location of the phrenic nerves. Direct electric stimulation of the phrenic nerve is usually applied in the case of long-term continuous support of respiratory function. Non-invasive techniques of electric or magnetic stimulation of the phrenic nerve or directly of the diaphragmatic muscle are used in the case of temporary respiratory support or recovery of diaphragm function. The motor neurons of the brain and peripheral nerves are activated, thus a peak strength of the variable magnetic field usually reachs 1-2 T in rPMS. Application of rPMS affects the efferent nerve fibers, causing muscle contractions, and activates sensory afferent fibers, creating a stimulating effect on the superjacent nervous structures. It is advisable to use rPMS of the phrenic nerve in the cervical segment or rPMS of one of the segments of the diaphragmatic muscle in the case of unilateral diaphragm lesion during the recovery period after stroke. It is important to consider the frequency of exposure in the 10-30 Hz range, the closest location of the coil to the stimulation area, the choice of the coil shape depending on the localization when adjusting parameters of rPMS.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusion: &lt;/strong&gt;The use of rPMS of the phrenic nerve and diaphragm allows to preserve and recover motor and contractile functions of the diaphragm in different pathological conditions, including its unilateral lesion as a result of stroke. The method of rPMS of the phrenic nerves has a number of advantages over electric stimulation and repetitive transcranial magnetic stimulation, since it allows to achieve an effective motor response","PeriodicalId":39492,"journal":{"name":"Voprosy kurortologii, fizioterapii, i lechebnoi fizicheskoi kultury","volume":"101 5","pages":"57-65"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142565185","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Influence of the method of manual-physical correction on autonomic regulation in patients with essential arterial hypertension]. [人工物理矫正方法对基本动脉高血压患者自律神经调节的影响]。
Q4 Medicine Pub Date : 2024-01-01 DOI: 10.17116/kurort202410105123
A Yu Shishonin, A A Vetcher, V I Pavlov

One of the methods of non-drug treatment of essential arterial hypertension, is manual, osteopathic effects on the spine, primarily the cervical spine. Despite the absence of these methods in clinical guidelines for essential arterial hypertension, they continue to develop and improve. One of the promising areas is manual-physical correction with an effect on the cervical spine and subsequent strengthening of the muscle corset with the help of physical exercises (method of A.Yu. Shishonin). One of the supposed mechanisms for reducing blood pressure (BP) in this case is the effect on the autonomic nervous system (ANS). In the course of the study, which was based on the study of heart rate variability (HRV), the presence of pronounced signs of a decrease in sympathetic influences and activation of the parasympathetic nervous system was shown. The parameters of statistical linear analysis (standard deviation of NN intervals; stress index, etc.) and the wave spectrum shifted towards sympathicotonia during therapy using the method of A.Yu. Shishonin. The HRV data were obtained against the background of a decrease in blood pressure and a decrease in heart rate (HR), which suggests the impact of manual physical correction on the ANS as one of the key mechanisms mediating its effect.

非药物治疗本质性动脉高血压的方法之一是对脊柱(主要是颈椎)进行人工整骨治疗。尽管在治疗本质性动脉高血压的临床指南中没有提及这些方法,但它们仍在不断发展和完善。其中一个很有前景的领域是对颈椎进行人工物理矫正,然后通过体育锻炼加强肌肉束带(A.Yu. Shishonin 的方法)。在这种情况下,降低血压(BP)的假定机制之一是对自律神经系统(ANS)的影响。在以心率变异性(HRV)为基础的研究过程中,出现了明显的交感神经影响减弱和副交感神经系统激活的迹象。在使用 A.Yu. Shishonin 方法进行治疗期间,统计线性分析参数(NN 间期标准偏差、压力指数等)和波谱向交感神经转移。Shishonin.心率变异数据是在血压下降和心率(HR)降低的背景下获得的,这表明人工物理矫正对自律神经系统的影响是其作用的关键机制之一。
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引用次数: 0
[Spinal manipulation techniques in the treatment of arterial hypertension. (A literature review)]. [脊柱手法技术在动脉高血压治疗中的应用。(文献综述)]。
Q4 Medicine Pub Date : 2024-01-01 DOI: 10.17116/kurort202410104152
A Yu Shishonin, I Bekkushe, A A Vetcher, V I Pavlov

There is a long-observed relationship between the pathology of the spine and arterial hypertension. There are a number of explanations for this, including one based on reflex effects and obstruction of blood flow to the cerebral vasodilatory centre localized in the rhomboid fossa projection. Obstruction can be absolute and relative, preventing the increase of blood flow during stress, when the brain turns on additional energy demand (phenomenon of «selfish brain»). In conditions of insufficient blood supply anaerobic metabolism is included, requiring in the future, the addition of anaerobic glycolysis products. This leads to the persistence of an elevated level of AD and is part of the theory of centralized compensation of aerobic-anaerobic balance (theoretical aerobic-anaerobic energy concept, TAAEBC). The existing methods of manual manipulation and physical action on the spine, mainly the atlantoacral section of the cervical spine, have, according to existing publications, varying degrees of effectiveness. The modern approach to treatment of arterial hypertension and correction of metabolic disorders by A. Shishonin is promising. It is based on the TAAEBC concept and assumes a system approach and long-term effect through a consistent three-step manual and physical interventions aimed at restoring, retaining and long-term support of the vertebral blood flow.

脊椎病变与动脉高血压之间的关系由来已久。对此有多种解释,其中一种是基于反射效应和位于斜方肌窝投影处的脑血管舒张中心的血流受阻。阻塞可能是绝对的,也可能是相对的,当大脑开启额外的能量需求("自私的大脑 "现象)时,压力会阻止血流量的增加。在供血不足的情况下,无氧新陈代谢也会出现,这就需要在未来增加无氧糖酵解产物。这导致 AD 水平持续升高,是有氧-无氧平衡集中补偿理论(理论有氧-无氧能量概念,TAAEBC)的一部分。根据现有出版物,对脊柱(主要是颈椎的寰椎部分)进行人工操作和物理作用的现有方法具有不同程度的有效性。A. Shishonin 提出的治疗动脉高血压和纠正代谢紊乱的现代方法很有前途。该方法以 TAAEBC 概念为基础,通过一致的三步人工和物理干预,旨在恢复、保持和长期支持椎体血流,从而实现系统方法和长期效果。
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引用次数: 0
[Historical aspects of the formation and development of children's health resort medicine in the Samara region]. [萨马拉地区儿童疗养院医学形成和发展的历史方面]。
Q4 Medicine Pub Date : 2024-01-01 DOI: 10.17116/kurort202410101162
E D Mokin, E E Achkasov, M V Nikitin, N A Mokina, A V Yashkov, L T Gil'mutdinova

Archive documents and sources in scientific electronic databases were analyzed in order to study the historical origins of the health resort business in terms of children's health resort medicine in the Samara government. It has been established that the period of origin and intensive development of balneology for children in the Samara region occurred at the beginning of the 20th century and the first children's sanatoriums began to function thanks to the initiative of the Society of Governmental Physicians for charitable funds of the Samara nobility and merchantry in territories with natural and climatic therapeutic factors, namely Sernovodsky resort, Barboshina glade and Postnikov ravine. A comparative analysis of the dynamics of morbidity structure of children admitted for sanatorium treatment, as well as general education institutions, from which information on the health of school pupils is received, has been conducted over a period of 120 years. Despite the change of years and generations, there is a general concept of sanatorium health improvement of school pupils as a future social and economic pillar of society, with the formation of a healthy generation for both the region and the country in general.

对科学电子数据库中的档案文件和资料来源进行了分析,以研究萨马拉政府儿童疗养院医学方面的疗养院业务的历史起源。在萨马拉贵族和商人的慈善基金政府医生协会的倡议下,第一批儿童疗养院开始在具有自然和气候治疗因素的地区(即谢尔诺沃茨基度假村、巴尔博希纳峡谷和波斯特尼科夫峡谷)运行。在 120 年间,对疗养院和普通教育机构中接受治疗的儿童的发病率结构动态进行了比较分析。尽管经历了岁月和时代的变迁,但人们仍然普遍认为,改善学生的疗养健康状况是未来社会和经济的支柱,为地区和国家培养健康的一代。
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引用次数: 0
[Sacral magnetic stimulation in overactive bladder syndrome: comparative analysis of protocols with a frequency of 1 and 5 Hz]. [骶磁刺激治疗膀胱过度活动综合征:频率为 1 赫兹和 5 赫兹的方案比较分析]。
Q4 Medicine Pub Date : 2024-01-01 DOI: 10.17116/kurort202410101122
I V Borodulina, G V Kovalev, I A Labetov, O V Volkova, D D Shkarupa, N G Badalov

Peripheral magnetic stimulation (pMS) has shown its effectiveness in the treatment of lower urinary tract symptoms, such as symptoms of an overactive bladder (OAB). The perineal region (pelvic floor) and the sacral roots area (projection S3 of the root) are used as the locus of stimulation. The published literature presents protocols with different parameters of stimulation, while each of them reliably demonstrates clinical efficacy, however, no comparative studies have been found to select priority stimulation modes when analyzing available sources.

Objective: To compare the efficacy and safety of different frequency - 1 and 5 Hz - modes of sacral MS in patients with symptoms of OAB.

Material and methods: A single blind prospective randomized comparative clinical study included 59 patients with OAB symptoms. The patients were divided by simple randomization into the group 1 (n=30), which received MS 3 times a week for 5 weeks with a frequency of 1 Hz per sacral root area (S2-S4), and the group 2 (n=29), in which stimulation was performed at a frequency of 5 Hz, while the remaining parameters and duration of therapy were identical to group 1.

Results: Sacral pMS with different frequency modes (1 and 5 Hz) is reliably equally effective against the clinical symptoms of OAB, which is confirmed by the absence of significant intergroup differences. In patients receiving MS with a frequency of 5 Hz, there was a more pronounced increase in maximum cystometric capacity, normalization of the maximum and average urine flow velocity and regression of the residual urine volume (p<0.001, p=0.007, p=0.011 and p=0.012 compared with group 1). The greatest difference in indicators was observed in the increase in the maximum cystometric capacity - +31±25 ml at MS with a frequency of 1 Hz and +109±96 ml at MS with a frequency of 5 Hz (p<0.001). MS is a safe procedure and is well tolerated by patients.

Conclusion: pMS when exposed to the area of S2-S4 roots for 20 minutes 3 times a week with a course for 5 weeks is reliably effective against the clinical symptoms of OAB at different frequency modes (1 and 5 Hz). At the same time, MS with a frequency of 5 Hz may have an advantage over stimulation of 1 Hz in terms of its effect on urodynamic parameters (maximum cystometric capacity, peak and average urine flow velocity and residual urine volume), which may be associated with a large inhibitory effect on detrusor.

外周磁刺激(pMS)在治疗下尿路症状(如膀胱过度活动症(OAB)症状)方面已显示出其有效性。会阴区域(骨盆底)和骶骨根部区域(骶骨根部 S3 投射)被用作刺激部位。已发表的文献介绍了具有不同刺激参数的方案,虽然每种方案都可靠地证明了临床疗效,但在分析现有资料来源时,尚未发现有比较研究可选择优先刺激模式:比较不同频率(1 赫兹和 5 赫兹)的骶管 MS 模式对有 OAB 症状患者的疗效和安全性:这是一项单盲前瞻性随机比较临床研究,共纳入 59 名有 OAB 症状的患者。这些患者被简单随机分为第1组(30人)和第2组(29人),前者每周3次、每次骶根区(S2-S4)的刺激频率为1赫兹,持续5周;后者的刺激频率为5赫兹,其余参数和疗程与第1组相同:结果:不同频率模式(1 赫兹和 5 赫兹)的骶管刺激对 OAB 临床症状同样有效,组间无明显差异证实了这一点。在接受频率为 5 赫兹的 MS 的患者中,最大膀胱容量、最大和平均尿流速度的正常化以及残余尿量的减少都有更明显的提高(与第 1 组相比,pp=0.007、p=0.011 和 p=0.012)。指标差异最大的是最大膀胱容量的增加--频率为 1 赫兹的 MS 增加了 +31±25 毫升,频率为 5 赫兹的 MS 增加了 +109±96 毫升(p 结论:在不同频率模式(1 赫兹和 5 赫兹)下,将 pMS 暴露于 S2-S4 根部区域,每周 3 次,每次 20 分钟,疗程 5 周,对 OAB 的临床症状有可靠的疗效。同时,在对尿动力参数(最大膀胱容量、峰值和平均尿流速度以及残余尿量)的影响方面,频率为 5 Hz 的 MS 可能比 1 Hz 的刺激更有优势,这可能与对排尿肌的巨大抑制作用有关。
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Voprosy kurortologii, fizioterapii, i lechebnoi fizicheskoi kultury
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