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[Effectiveness of physical rehabilitation methods based on the impact of eccentric load in upper limb injuries]. [基于偏心负荷影响的物理康复方法对上肢损伤的疗效]。
Q4 Medicine Pub Date : 2024-01-01 DOI: 10.17116/kurort202410103113
I S Khadakhanov, D A Stepanenko, V I Pavlov, N M Kozlova, A Yu Shishonin, A A Vecher

The rehabilitation of patients after upper limb injuries is becoming increasingly relevant in current medical practice considering that this pathology is often occurred in professional athletes, elderly people, people with active lifestyle.

Objective: To study the effectiveness of isolated therapeutic exercises (TE) with eccentric muscle loads when using rubber cable compared to traditional TE to restore functional capabilities of patients after upper limb injuries.

Material and methods: The study included 38 patients with upper limb injuries diagnosed by orthopedic surgeon. Patients were randomly enrolled into group of isolated TE with eccentric muscle loads (group A, 20 patients, mean age 40.2±10.8 years) and group of traditional exercises (group B, 18 patients, mean age 38.6±12.3 years). The study consisted of anamnesis taking, clinical examination, functional tests applying (isometric dynamometry, joint mobility tests, functional scales and questionnaires). The rehabilitation effectiveness was assessed by comparing the indicators before and after treatment course.

Results: There has been a significant improvement in muscle strength, movement amplitude and decrease of pain syndrome in patients rehabilitated by eccentric muscle loads. A comparison with a control group using traditional TE methods confirmed the superiority of eccentric exercises in reducing recovery time and improving functional performance.

Conclusion: The study confirmed the high effectiveness of eccentric muscular loads in the rehabilitation of patients after upper limb injuries. The method has shown significant improvement in clinical and functional indices, which allows to recommend it for inclusion in standard rehabilitation protocols. Further researches may extend application of this approach and reveal the TE effectiveness in other types of traumas and orthopedic injuries.

考虑到上肢损伤通常发生在专业运动员、老年人和生活方式活跃的人群中,上肢损伤后患者的康复在当前的医疗实践中正变得越来越重要:研究使用橡皮索进行偏心肌肉负荷的孤立治疗运动(TE)与传统治疗运动相比,对恢复上肢损伤后患者功能的有效性:研究对象包括 38 名经骨科医生诊断为上肢损伤的患者。将患者随机分为带偏心肌肉负荷的孤立 TE 组(A 组,20 名患者,平均年龄(40.2±10.8)岁)和传统锻炼组(B 组,18 名患者,平均年龄(38.6±12.3)岁)。研究包括病史采集、临床检查、功能测试(等距测力、关节活动度测试、功能量表和问卷调查)。通过比较治疗前后的各项指标来评估康复效果:结果:接受偏心肌肉负荷康复治疗的患者在肌肉力量、运动幅度和疼痛综合征方面都有明显改善。通过与使用传统 TE 方法的对照组进行比较,证实了偏心运动在缩短恢复时间和改善功能表现方面的优越性:研究证实,偏心肌肉负荷对上肢损伤后患者的康复非常有效。该方法显著改善了临床和功能指标,因此建议将其纳入标准康复方案。进一步的研究可能会扩大这种方法的应用范围,并揭示 TE 在其他类型的创伤和骨科损伤中的有效性。
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引用次数: 0
[Rehabilitation of patients after spinal surgery: effectiveness of nonthermal techniques of peloidotherapy]. [脊柱手术后患者的康复:非热效应骨盆疗法的有效性]。
Q4 Medicine Pub Date : 2024-01-01 DOI: 10.17116/kurort202410104123
A G Kulikov, T Yu Gaydukova, N V Lvova, D V Baymuratova

The problem of patients' rehabilitation after spinal surgery remains relevant. The use of therapeutic physical factors, both preformed and natural, including pelotherapy, is very important. The application of the latter requires to develop new techniques in this pathology, one of which is low temperature exposure.

Objective: To study the possibility and to assess the effectiveness of resource-saving nonthermal pelotherapy techniques in patients' rehabilitation, who underwent surgeries for intervertebral discs' herniation.

Material and methods: The number of patients equal 88, including 39 males and 49 females, after lumbar microdiscectomy, was examined in this study. The patients were divided into 3 groups. Control group (28 patients) received a basic rehabilitation complex (therapeutic gymnastics, massage, low-frequency magnetotherapy); the 1st study group (30 patients) - basic complex and procedures of thin layer applications with peat muds preparation (Tomed-applikat) at 20-24 °C; the 2nd study group (30 patients) - basic complex and procedures of fluctuoresis of 2% solution of peat mud Tomed-aqua preparation.

Results: There was a significant reduction of pain syndrome, recovery of sensitivity and motor activity, decrease of Oswestry index, characterizing the degree of vital activity disturbance, in patients of the study group compared to the control group after treatment.

Conclusion: The inclusion of nonthermal resource-saving techniques of pelotherapy in rehabilitation complex of patients who underwent spinal surgery is effective and pathogenetically justified.

脊柱手术后患者的康复问题仍然十分重要。使用预制的和天然的物理治疗因子(包括骨盆疗法)非常重要。后者的应用需要在这一病理学领域开发新技术,低温照射就是其中之一:研究节省资源的非热疗技术在因椎间盘突出而接受手术的患者康复中的可能性,并评估其有效性:研究对象为腰椎间盘显微切除术后的 88 名患者,包括 39 名男性和 49 名女性。患者分为 3 组。对照组(28 名患者)接受基本康复综合疗法(治疗体操、按摩、低频磁疗);第一研究组(30 名患者)--基本综合疗法和泥炭泥制剂(Tomed-applikat)薄层涂抹疗法,温度为 20-24 °C;第二研究组(30 名患者)--基本综合疗法和 2% 泥炭泥 Tomed-aqua 溶液波动疗法:结果:与对照组相比,研究组患者在治疗后疼痛综合征明显减轻,敏感性和运动活动得到恢复,表征生命活动障碍程度的Oswestry指数下降:结论:在脊柱手术患者的康复综合治疗中纳入非热资源节约型骨盆疗法技术是有效的,在病理学上也是合理的。
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引用次数: 0
[Method of manual-physical correction in the treatment of hypertensive disease and normalization of psychoneurological status in patients with degenerative-dystrophic processes of the musculoskeletal system]. [肌肉骨骼系统退行性萎缩过程患者高血压疾病治疗和精神神经状态正常化的手动物理矫正方法]。
Q4 Medicine Pub Date : 2024-01-01 DOI: 10.17116/kurort202410104116
E V Yakovleva, K V Zhukov, A A Vetcher, B A Gasparyan, A Yu Shishonin, V I Pavlov

There are some non-communicable diseases (NCD) associated with arterial hypertension (AHT) that are cured after recovery from AHT. Recently confirmed the theory of centralized aerobic-anaerobic energy balance compensation (TCAAEBC) originated some NCDs with the obstructions of arterial blood flow access to the rhomboid fossa. For some sergeants, this has already been demonstrated. Since neurological NCDs are similarly considered by TCAAEBC, it is logical to analyze dynamics of such musculoskeletal neurological problem as isolated musculoskeletal chest pain (IMCP) in connection with the therapy based on TCAAEBC. We retrospectively evaluated the medical records of adult patients with AHT, simultaneously suffering from IMCP. All these patients underwent complex treatment including manual techniques that restore arterial blood flow to the rhomboid fossa, followed by therapy that strengthens the muscular corset primarily of the cervical region. This, in addition to the normalization of AHT, led to a decrease in the musculoskeletal pain syndrome. The dynamic of pain was recorded according to four questionaries - Oswestry Disability Index (ODI) Hospital Anxiety and Depression Scale (HADS), Numerical Rating Scale (NRS), and the Quality-of-life assessment questionnaire (SF-12). The collected data were analyzed with the Wilcoxon signed-rank test, which confirms the recovery of the patients from both AHT and IMCP.

有一些与动脉高血压(AHT)相关的非传染性疾病(NCD)在动脉高血压康复后可以治愈。最近证实的集中式有氧-无氧能量平衡补偿(TCAAEBC)理论起源于菱形窝动脉血流通道受阻的一些非传染性疾病。对于一些军士来说,这一点已经得到证实。既然神经性非传染性疾病也同样被 TCAAEBC 考虑在内,那么分析此类肌肉骨骼神经性问题(如孤立性肌肉骨骼胸痛 (IMCP))与基于 TCAAEBC 的治疗之间的动态关系也就顺理成章了。我们回顾性评估了同时患有孤立性肌肉骨骼胸痛(IMCP)的 AHT 成年患者的病历。所有这些患者都接受了复杂的治疗,包括恢复斜方肌窝动脉血流的手动技术,以及主要加强颈部肌肉束带的治疗。这样,除了 AHT 恢复正常外,肌肉骨骼疼痛综合征也有所减轻。疼痛的动态变化根据四种问卷进行记录--奥斯韦特里残疾指数(ODI)、医院焦虑抑郁量表(HADS)、数值评定量表(NRS)和生活质量评估问卷(SF-12)。收集到的数据通过 Wilcoxon 符号秩检验进行了分析,结果表明,AHT 和 IMCP 患者均已康复。
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引用次数: 0
[Rehabilitation potential of patients with ischemic heart disease who underwent autovenous coronary artery bypass surgery in the evaluation of rehabilitation treatment effectiveness]. [接受自体静脉冠状动脉搭桥手术的缺血性心脏病患者的康复潜力在康复治疗效果评估中的应用]。
Q4 Medicine Pub Date : 2024-01-01 DOI: 10.17116/kurort202410105129
S G Abramovich, O O Knyazyuk, I M Mikhalevich, V A Drobyshev, E A Shchedreeva

The search for methods to assess the rehabilitation potential (RP) of patients with ischemic heart disease (IHD) who underwent coronary artery bypass surgery (CABS), which will allow to personalize approaches to the administration of necessary for the certain patient treatment complexes, increasing their effectiveness and reducing the probability of complications, remains relevant.

Objective: To develop a method for RP evaluation in patients with IHD who underwent CABS and to assess its role in predicting the effectiveness of therapeutic activities in the early rehabilitation period.

Material and methods: The study consisted of two parts. A method for RP assessment in 118 patients with IHD aged 36-85 years (mean age 62.3±2.0 years) who underwent CABS was developed in the 1st part based on the analysis of hospital discharge reports using mathematical modeling methods. The results of rehabilitation activities were analyzed in the 2nd part of the study in patients who were transferred to the cardiovascular department of the Angara Clinical Resort after the cardiovascular surgery department for the second stage of rehabilitation. The multidisciplinary team evaluated the effectiveness of patients' treatment after the rehabilitation completion using integral indicators characterizing clinical condition of the patient who underwent CABS.

Results: A methodological algorithm was created in the 1st part of the study, namely a formalized patient chart was formed, the evidence base was represented by 99 indicators. The values of linear classification functions' coefficients were assigned to certain indicators, according to which the patient was classified into one of four groups: the 1st group - without RP; the 2nd group - with medium RP; the 3rd group - with high RP and the 4th group - with low RP. The values of RP were determined in the second part of the study for predicting the effectiveness of therapeutic measures in the early rehabilitation period (the second stage of medical rehabilitation). It has been found that the greatest effect was observed in subjects of the 3rd group with high RP in the patients' testing after treatment at the health resort. The lesser effect has been noted in patients of the 2nd group and especially of the 4th group.

Conclusions: The use of RP assessment method based on mathematical modeling in patients who underwent CABS allows to predict the results of patients' medical rehabilitation at the second stage in the health resort conditions.

寻找对接受冠状动脉搭桥手术(CABS)的缺血性心脏病(IHD)患者的康复潜力(RP)进行评估的方法仍具有现实意义,这将使针对特定患者的必要治疗综合方案的个性化管理方法成为可能,从而提高其有效性并降低并发症的发生概率:开发一种方法,用于对接受 CABS 的 IHD 患者进行 RP 评估,并评估其在预测早期康复期治疗活动有效性方面的作用:研究由两部分组成。第一部分是在使用数学建模方法分析出院报告的基础上,对 118 名年龄在 36-85 岁(平均年龄为 62.3±2.0 岁)接受 CABS 的 IHD 患者进行 RP 评估。在研究的第二部分,对心血管外科手术后转入安加拉临床度假村心血管科进行第二阶段康复治疗的患者的康复活动结果进行了分析。多学科小组在患者康复结束后,利用表征接受心血管外科手术患者临床状况的综合指标对患者的治疗效果进行了评估:研究的第一部分创建了一个方法算法,即形成了一个正式的病人图表,证据基础由 99 个指标表示。将线性分类函数的系数值分配给某些指标,根据这些指标将患者分为四组:第一组--无RP;第二组--中等RP;第三组--高RP;第四组--低RP。研究的第二部分确定了 RP 值,以预测早期康复期(医疗康复的第二阶段)治疗措施的效果。研究发现,在疗养院治疗后的患者测试中,RP 值较高的第三组受试者的效果最好。第二组,尤其是第四组患者的效果较差:在接受 CABS 的患者中使用基于数学建模的 RP 评估方法,可以预测患者在疗养院条件下第二阶段医疗康复的结果。
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引用次数: 0
[Comprehensive approach to rehabilitation of patients with COVID-19. (A literature review)]. [COVID-19患者康复的综合方法。(文献综述)]。
Q4 Medicine Pub Date : 2024-01-01 DOI: 10.17116/kurort202410103148
M S Petrova

The COVID-19 epidemic has made significant changes in the organization of treatment process both at the inpatient and outpatient stages.

Objective: To analyze the work results of the rehabilitation units dealing with patients who have suffered from COVID-19, in order to summarize the used approaches to medical rehabilitation and improve the effectiveness of care delivery in the recovery phase.

Results and conclusion: Currently, the rehabilitation system has been effectively rebuilt to meet new challenges of the COVID-19 pandemic. Recovery of patients with pronounced neurotic disorders has become a showing good results direction in rehabilitation. It is necessary to implement a tight integration of physical exercises and telerehabilitation facilities in order to effectively settle the main issues directly related to the treatment and recovery of patients with COVID-19 and other pathologies. The control, prevention, treatment and rehabilitation of other infectious diseases will have great prospects regarding the possibility of remote follow-up of patients and correction of their functional state of the body in the nearest future.

COVID-19 的流行使住院和门诊阶段的治疗过程组织发生了重大变化:目的:分析处理 COVID-19 患者的康复部门的工作成果,以总结所采用的医疗康复方法,提高康复阶段的护理效果:目前,康复系统已得到有效重建,以应对 COVID-19 大流行带来的新挑战。有明显神经障碍的患者的康复已成为康复工作中一个显示良好效果的方向。有必要将体育锻炼和远程康复设施紧密结合起来,以有效解决与 COVID-19 和其他病症患者的治疗和康复直接相关的主要问题。在不久的将来,其他传染病的控制、预防、治疗和康复将在远程跟踪病人和纠正其身体功能状态的可能性方面具有广阔的前景。
{"title":"[Comprehensive approach to rehabilitation of patients with COVID-19. (A literature review)].","authors":"M S Petrova","doi":"10.17116/kurort202410103148","DOIUrl":"https://doi.org/10.17116/kurort202410103148","url":null,"abstract":"<p><p>The COVID-19 epidemic has made significant changes in the organization of treatment process both at the inpatient and outpatient stages.</p><p><strong>Objective: </strong>To analyze the work results of the rehabilitation units dealing with patients who have suffered from COVID-19, in order to summarize the used approaches to medical rehabilitation and improve the effectiveness of care delivery in the recovery phase.</p><p><strong>Results and conclusion: </strong>Currently, the rehabilitation system has been effectively rebuilt to meet new challenges of the COVID-19 pandemic. Recovery of patients with pronounced neurotic disorders has become a showing good results direction in rehabilitation. It is necessary to implement a tight integration of physical exercises and telerehabilitation facilities in order to effectively settle the main issues directly related to the treatment and recovery of patients with COVID-19 and other pathologies. The control, prevention, treatment and rehabilitation of other infectious diseases will have great prospects regarding the possibility of remote follow-up of patients and correction of their functional state of the body in the nearest future.</p>","PeriodicalId":39492,"journal":{"name":"Voprosy kurortologii, fizioterapii, i lechebnoi fizicheskoi kultury","volume":"101 3","pages":"48-55"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141459800","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Effect of low-intensity laser-therapy in the correction of encephalopathy in obstructive jaundice]. 低强度激光治疗梗阻性黄疸脑病的疗效观察。
Q4 Medicine Pub Date : 2024-01-01 DOI: 10.17116/kurort202410106119
I A Chigakova, I A Minenko, O A Strokova, E R Nazarova

Hepatic encephalopathy is an early and severe complication of obstructive jaundice and is characterized by occurrence of non-focal and focal neurological manifestations. Different methods of therapy are applied for disorder correction. Low-intensity laser blood irradiation has a pronounced antioxidant and vasoactive effect.

Objective: To analyze the results of pharmaceutical treatment and low-intensity laser therapy use in encephalopathy correction in obstructive jaundice of non-neoplastic origin.

Material and methods: The study was performed at the surgery department in the S.V. Katkov Republican Clinical Hospital (Saransk). The trial included 54 patients with moderate obstructive jaundice of non-neoplastic origin with latent encephalopathy, who were divided into 2 groups: the 1st group (control) consisted of 27 patients receiving standard pharmaceutical treatment; the 2nd group (study) - 27 patients receiving standard treatment and laser therapy (low-intensity laser irradiation in red emission at the cubital vein projection for 15 minutes). A comparative group (norm) included 20 healthy volunteers. All patients underwent biochemical studies (alanine aminotransferase and total bilirubin levels in the blood were assessed) after treatment. Registration of microcirculatory disorders and psychometric testing were conducted to reveal latent hepatic encephalopathy along with the evaluation of liver functional condition.

Results: Correlation analysis showed the association of psychoneurological status improvement with liver functional condition (indicators of microcirculation and biochemical blood analysis were considered) in patients receiving a comprehensive therapy with laser irradiation. Correlation coefficient amounted to 0.87-0.96 (p<0.05).

Conclusion: The use of above vascular laser blood irradiation in a comprehensive treatment of moderate obstructive jaundice leads to improvement of liver functional condition (the first barrier organ on the toxin pathway) and to a significant reduction of latent encephalopathy's manifestations. The conducted treatment resulted in a reduction of initially elevated levels of alanine aminotransferase and total bilirubin. Laser therapy has an ability to restore microcirculation that leads to the improvement of psychoneurological status in patients with moderate obstructive jaundice.

肝性脑病是梗阻性黄疸的早期严重并发症,其特点是出现非局灶性和局灶性神经系统表现。不同的治疗方法被用于矫正障碍。低强度激光血液照射具有明显的抗氧化和血管活性作用。目的:分析药物治疗与低强度激光治疗在非肿瘤性梗阻性黄疸脑病矫正中的应用效果。材料和方法:研究在S.V. Katkov共和国临床医院(Saransk)的外科进行。试验纳入54例伴有潜伏性脑病的非肿瘤性中度梗阻性黄疸患者,分为2组:第一组(对照组)27例患者接受标准药物治疗;第二组(研究):27例患者接受标准治疗和激光治疗(低强度激光红光照射肘静脉投影15分钟)。对照组为20名健康志愿者。治疗后,所有患者进行生化检查(评估血液中丙氨酸转氨酶和总胆红素水平)。通过微循环疾病登记和心理测试来发现潜在的肝性脑病,同时评估肝功能状况。结果:相关分析显示,在接受激光综合治疗的患者中,心理神经状态的改善与肝功能状况(考虑微循环指标和血液生化分析)相关。结论:应用上述血管激光血液照射综合治疗中度梗阻性黄疸,可改善肝功能(毒素通路第一屏障器官),显著减少潜伏性脑病的表现。所进行的治疗导致最初升高的丙氨酸转氨酶和总胆红素水平降低。激光治疗能够恢复微循环,从而改善中度梗阻性黄疸患者的神经心理状态。
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引用次数: 0
[Efficacy of manual correction of cervical spine osteochondrosis in the treatment of arterial hypertension syndrome and prediabetes]. [人工矫正颈椎骨软骨病对治疗动脉高血压综合征和糖尿病前期的疗效]。
Q4 Medicine Pub Date : 2024-01-01 DOI: 10.17116/kurort202410102112
A Yu Shishonin, E V Yakovleva, K V Zhukov, A A Vecher, B A Gasparyan, V I Pavlov

Cardiovascular diseases and diabetes mellitus, debuting as arterial hypertension (AH) syndrome and prediabetes, are common types of chronic non-communicable processes, that are the leading cause of death in the world. The main treatment method for above mentioned disorders, according to the current guidelines, is pharmacotherapy. However, it is possible to effectively apply non-pharmacological correction methods, aimed at the probable etiological factor and inversive mechanism involved in AH maintenance, in the early stages when no permanent changes are maintaining a high level of blood hypertension (BH) and glycemia. Frequently, this mechanism is hypoxia in the vertebral arteries system due to cervical spine osteochondrosis.

Objective: To evaluate the therapeutic effect of non-pharmacological methods of restoring brainstem blood supply in patients with AH and prediabetes.

Material and methods: The number of patients equal 125 (57 men and 68 women, mean age 63.3±11.5 and 65.4±11.8 y.o., respectively) with prediabetes and 1st degree of AH without target organs damage, among whom 102 patients with prehypertension or 1st degree of hypertension and 24 ones with 2nd degree of hypertension, were examined. The original method of manually restoring brainstem blood supply developed in the Shishonin's Clinic was applied to all patients. The control group included patients with the same disorder, who did not receive manipulations. Blood pressure (BP) measurement, ultrasound and triplex ultrasonography of vertebral arteries, biochemical blood test, and estimation of glycemia and glycated hemoglobin were performed.

Results: All patients of the study group had decreased levels of systolic BP (by 23.8±10.7 mm Hg for men and 32.8±11.9 mm Hg for women), an increase of flow velocity in vertebral arteries (by 20.6±7.5 and 21.5±7.2 cm/s, respectively), a decrease of glycated hemoglobin concentration (by 0.32±0.51 and 0.34±0.41%, respectively). In the comparison group, there were no patients with improvement in these indicators.

Conclusion: The effectiveness of the author's manual method of cervical spine osteochondrosis correction in the reduction of BP and glycemia levels in the early stages of the disease is shown.

心血管疾病和糖尿病,最初表现为动脉高血压(AH)综合征和糖尿病前期,是常见的慢性非传染性疾病,也是世界上最主要的死亡原因。根据现行指南,上述疾病的主要治疗方法是药物疗法。然而,在高血压(BH)和高血糖没有永久性改变的早期阶段,可以有效地采用非药物矫正方法,针对可能的致病因素和 AH 维持的逆转机制进行治疗。这种机制通常是颈椎骨软骨病导致的椎动脉系统缺氧:评估非药物方法恢复 AH 和糖尿病前期患者脑干供血的治疗效果:研究对象: 125例(男57例,女68例,平均年龄(63.3±11.5)岁和(65.4±11.8)岁)糖尿病前期合并1度AH且无靶器官损害的患者,其中高血压前期或1度高血压患者102例,2度高血压患者24例。所有患者均采用了 Shishonin 诊所独创的人工恢复脑干供血的方法。对照组包括患有相同疾病但未接受治疗的患者。对所有患者进行了血压测量、椎动脉超声波和三倍超声波检查、血液生化检查、血糖和糖化血红蛋白测定:研究组所有患者的收缩压均有所下降(男性为 23.8±10.7 mm Hg,女性为 32.8±11.9 mm Hg),椎动脉流速有所上升(分别为 20.6±7.5 cm/s 和 21.5±7.2 cm/s),糖化血红蛋白浓度有所下降(分别为 0.32±0.51% 和 0.34±0.41%)。对比组中,没有患者在这些指标上有所改善:作者的颈椎骨软骨病手工矫正方法在疾病早期降低血压和血糖水平的效果显著。
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引用次数: 0
[Pelotherapy and pelotherapy combined with intravenous laser blood irradiation at the sanatorium-resort stage of treatment of patients with psoriasis vulgaris]. [在治疗寻常型银屑病患者的疗养院阶段,颗粒疗法和颗粒疗法结合静脉激光血液照射]。
Q4 Medicine Pub Date : 2024-01-01 DOI: 10.17116/kurort202410102124
L N Gumenyuk, M Yu Kuznetsova, M B Ispiryan, U I Basnaev, N E Karakursakov

Search of new rational ways to increase the effectiveness of treatment and rehabilitation measures for patients with psoriasis vulgaris continues to be one of the urgent problems in modern clinical dermatology.

Objective: To carry out a comparative analysis of the impact of different variants of sanatorium-resort treatment (SRT) - pelotherapy and pelotherapy in combination with intravenous laser blood irradiation (ILBI) - on the level of IL-17 and TNF-a, dermatological status, psychoemotional state and quality of life (QL) assessment of patients with psoriasis vulgaris.

Material and methods: A naturalistic comparative study included 120 patients with psoriasis vulgaris, who were undergoing SRT: 57 patients in the pelotherapy group and 63 in the group of pelotherapy in combination with ILBI. The SRT effectiveness was assessed using the PASI index, the HARS and HDRS scales and the DLQI questionnaire. The dynamics of IL-17 and TNF-a plasma levels in blood plasma was studied. The study duration was 6 months 14 days.

Results: After 14 days of SRT, a decrease in IL-17 and TNF-a levels in blood plasma was statistically significant both in the pelotherapy group and in the group of pelotherapy in combination with ILBI, no statistically significant differences between the groups were found. Furthermore, the comprehensive use of pelotherapy in combination with ILBI has contributed to a more pronounced statistically significant decrease in the PASI index, the HARS and HDRS scales' total scores and an increase in the level of QL. The number of patients with clinical remission was statistically higher in the group of pelotherapy combined with ILBI compared to the pelotherapy group (87.3% versus 42.1%) six months after SRT.

Conclusion: The advantage of comprehensive application of pelotherapy and ILBI in comparison with pelotherapy in patients with psoriasis vulgaris in SRT has been shown. The comprehensive application of pelotherapy and ILBI reduces the level of inflammatory biomarkers, improves dermatological and psychoemotional status, improves QL and is well tolerated by patients.

寻找新的合理方法来提高寻常型银屑病患者治疗和康复措施的有效性,仍然是现代临床皮肤病学亟待解决的问题之一:目的:比较分析不同疗养治疗(SRT)变体--颗粒疗法和颗粒疗法联合静脉激光血液照射(ILBI)--对寻常型银屑病患者IL-17和TNF-a水平、皮肤状况、心理情绪状态和生活质量(QL)评估的影响:一项自然比较研究纳入了120名正在接受SRT治疗的寻常型银屑病患者:57名患者属于颗粒疗法组,63名患者属于颗粒疗法联合ILBI组。SRT的有效性通过PASI指数、HARS和HDRS量表以及DLQI问卷进行评估。同时还研究了血浆中IL-17和TNF-a血浆水平的动态变化。研究持续时间为 6 个月 14 天:结果:经过 14 天的 SRT 治疗后,颗粒疗法组和颗粒疗法联合 ILBI 组血浆中 IL-17 和 TNF-a 水平的下降均有统计学意义,组间差异无统计学意义。此外,颗粒疗法联合 ILBI 的综合应用还促使 PASI 指数、HARS 和 HDRS 量表总分有了更明显的统计学意义上的显著下降,并提高了 QL 水平。与颗粒疗法组相比,颗粒疗法联合 ILBI 组在 SRT 6 个月后临床缓解的患者人数在统计学上更高(87.3% 对 42.1%):结论:在SRT治疗寻常型银屑病患者时,综合应用颗粒疗法和ILBI与颗粒疗法相比具有优势。综合应用骨盆疗法和 ILBI 降低了炎症生物标志物的水平,改善了皮肤和心理情绪状况,提高了患者的生活质量,而且患者的耐受性良好。
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引用次数: 0
[Development of adaptive reactions when applying drinking mineral water and electromagnetic radiation against the background of a high-calorie diet on the model of experimental metabolic syndrome]. [在实验性代谢综合征模型上,以高热量饮食为背景,应用饮用矿泉水和电磁辐射时适应性反应的发展]。
Q4 Medicine Pub Date : 2024-01-01 DOI: 10.17116/kurort202410101142
Yu N Korolev, L A Nikulina, L V Mikhailik

Objective: To identify features of development of adaptive protective reactions when applying drinking sulfate mineral water (MW) and low-intensity electromagnetic radiation of extremely high frequency (EMR EHF) against the background of a high-calorie diet and after its elimination at an early stage of development of experimental metabolic syndrome.

Material and methods: Experiments were conducted on 40 non-linear male rats with 200-220 g. weight. The model of metabolic syndrome was reproduced for 60 days. All animals were divided into 5 groups: 2 study groups, 2 control groups and 1 intact one. Rats of the 1st study group were given sulfate MW in combination with EMR EHF against the background of a high-calorie diet, controlled by rats receiving only a high-energy diet. Rats of the 2nd study group also received sulfate MW in combination with EMR EHF but when the metabolic syndrome simulation was finished and the high-calorie diet was eliminated, control was done by rats that were given standard food after eliminating the high-energy diet. Liver, testes and blood were objects of the study. Light-optical, morphometric methods of examination and electron microscopy were used.

Results and discussion: The use of sulfate MW in combination with EMR EHF against the background of the high-calorie diet was the most cause of increased activity of the antioxidant system and the plastic processes were weaker; the activation of natural adaptive reactions was noted after the elimination of the diet that in combination with actions of MW and EMR EHF led to the further intensification of protein synthesis (RNA, DNA, total protein), intensification of cellular and intracellular regeneration processes. The identified adaptive shifts during the action of the studied factors were caused by their antioxidant, membrane stabilizing and detoxifying actions.

Conclusion: The results of the study can be used to develop the problem of regulating adaptive reactions with the application of therapeutic physical factors and to create new highly effective methods of preventing and treating metabolic syndrome.

研究目的在实验性代谢综合征的早期阶段,确定在高热量饮食背景下饮用硫酸盐矿泉水(MW)和低强度极高频率电磁辐射(EMR EHF),以及在消除硫酸盐矿泉水和低强度极高频率电磁辐射后,适应性保护反应的发展特征:实验对象为 40 只体重为 200-220 克的非线性雄性大鼠。代谢综合征模型重现时间为 60 天。所有动物分为 5 组:2 个研究组、2 个对照组和 1 个完整组。第一研究组的大鼠在高热量饮食的背景下服用硫酸盐 MW 和 EMR EHF,对照组的大鼠只服用高能量饮食。第 2 研究组的大鼠也接受了硫酸盐 MW 与 EMR EHF 联合治疗,但在代谢综合征模拟治疗结束后,取消了高热量饮食,由取消高能量饮食后食用标准食物的大鼠进行对照。研究对象包括肝脏、睾丸和血液。使用了光学、形态计量学和电子显微镜检查方法:在高热量饮食的背景下,硫酸盐 MW 与 EMR EHF 的结合使用是导致抗氧化系统活性增强和塑性过程减弱的最主要原因;消除饮食后,自然适应反应被激活,与 MW 和 EMR EHF 的作用相结合,导致蛋白质合成(RNA、DNA、总蛋白)进一步增强,细胞和细胞内再生过程增强。在所研究因子的作用过程中发现的适应性转变是由它们的抗氧化、膜稳定和解毒作用引起的:研究结果可用于解决应用治疗性物理因子调节适应性反应的问题,并创造出预防和治疗代谢综合征的高效新方法。
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引用次数: 0
[On the Draft Regulations on Districts of Sanitary (Mountain Sanitary) Protection of Natural Medicinal Resources: Comments, Suggestions]. [关于《天然药材资源卫生(山区卫生)保护区条例(草案)》:意见、建议]。
Q4 Medicine Pub Date : 2024-01-01 DOI: 10.17116/kurort202410101148
A N Razumov, V B Adilov, N V Lvova, A G Kulikov, Yu A Pakhomova, D N Kuklin, I P Piskovtseva, A A Shershakov

The purpose of the article is to attract the attention of specialists in the resort business in the document being developed - the Decree of the Government of the Russian Federation «On Approval of the Regulations on the Districts of Sanitary (Mining and Sanitary) Protection of Natural Medicinal Resources», the draft of which is proposed for discussion. The article presents all the comments on the discussed draft Regulation and proposals for making appropriate changes with their reasoned justification. The proposals put forward to change the wording of specific paragraphs of the Regulation are aimed at protecting and preserving the wealth of our country - natural healing factors that form the basis of sanatorium treatment. The proposals made to edit the paragraphs of the Regulation will undoubtedly guarantee the preservation of Russia's natural healing resources in order to use them for the prevention, treatment and rehabilitation of the population of our country and the successful development of the resort industry.

本文旨在吸引度假区专家关注正在制定的文件--"关于批准天然药用资源卫生(采矿和卫生)保护区条例 "的俄罗斯联邦政府令,该文件草案已提交讨论。文章介绍了对已讨论的《条例》草案的所有评论意见以及进行适当修改的建议,并说明了理由。修改《条例》具体段落措辞的建议旨在保护和保存我国的财富--构成疗养治疗基础的自然疗法因素。对《条例》段落进行修改的建议无疑将确保俄罗斯的自然疗法资源得到保护,以用于我国居民的 预防、治疗和康复以及度假产业的成功发展。
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引用次数: 0
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Voprosy kurortologii, fizioterapii, i lechebnoi fizicheskoi kultury
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