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Workplace violence in a tertiary health-care institute in Manipur: A cross-sectional study 曼尼普尔一家三级保健机构的工作场所暴力:一项横断面研究
Q4 Medicine Pub Date : 2020-05-01 DOI: 10.4103/jms.jms_30_20
B. Rajkumari, Joymati Oinam, Tamphasana Thounaojam
Background: Workplace violence is much prevalent across the globe in almost all institutions dealing directly with the general public and hospitals are no exception to it. Therefore, the objective of this study is to determine the prevalence of workplace violence among doctors and nurses in a tertiary health-care institute in Manipur and to discuss the contributing factors and preventive measures against workplace violence. Materials and Methods: A cross-sectional study was conducted from March to April 2019 among a sample of 438 among doctors and nurses of clinical departments of a tertiary health-care institute, Manipur. A predesigned self-administered questionnaire which was modified and adopted from the “Workplace Violence in the Health Sector Country Case Study-Questionnaire” was used for data collection. Data were analyzed using SPSS IBM Statistics version 21. Statistical analyses such as mean, standard deviation (SD), proportion, and Chi-squared (χ2) test were performed taking P < 0.05 as statistically significant. Results: The mean (±SD) age was 31.02 (±7.1) years. About 32.8% had experienced at least one form of violence. Verbal abuses were the most common form (72.8%). Staff nurses (45.7%) faced the maximum number of incidents. Significantly male staff faced more workplace violence than females. Conclusion: The prevalence of workplace violence was a little more than 1 out of 4. Verbal abuse was the most common workplace violence. The communication gap (123, 49.8%) was cited as the main cause of workplace violence. Increasing security measures and limiting numbers of patient's attendants are required to deal with workplace violence.
背景:工作场所暴力在全球几乎所有直接与公众打交道的机构中都很普遍,医院也不例外。因此,本研究的目的是确定曼尼普尔一所三级医疗机构医生和护士中工作场所暴力的流行率,并讨论影响工作场所暴力行为的因素和预防措施。材料和方法:2019年3月至4月,在曼尼普尔一家三级医疗机构临床科室的438名医生和护士中进行了一项横断面研究。数据收集使用了一份预先设计的自我管理问卷,该问卷是从“卫生部门工作场所暴力国家案例研究问卷”中修改和采用的。使用SPSS IBM Statistics version 21对数据进行分析。进行统计学分析,如平均值、标准差(SD)、比例和卡方检验(χ2),P<0.05为统计学显著性。结果:平均(±SD)年龄为31.02(±7.1)岁。约32.8%的人至少经历过一种形式的暴力。言语虐待是最常见的形式(72.8%)。护士(45.7%)面临的事件最多。值得注意的是,男性员工比女性员工面临更多的工作场所暴力。结论:工作场所暴力的发生率略高于四分之一。言语虐待是最常见的职场暴力。沟通差距(12349.8%)被认为是工作场所暴力的主要原因。应对工作场所暴力需要加强安全措施并限制患者护理人员的数量。
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引用次数: 0
A prospective study on the role of removal of pretarsal tissue in Asian blepharoplasty 额前组织切除术在亚洲眼睑整形术中作用的前瞻性研究
Q4 Medicine Pub Date : 2020-05-01 DOI: 10.4103/jms.jms_123_20
Suiyibangbe, A. Singh, A. Choudhary, Saugat Das, L. Singh, N. Singh
Background: Surgical creation of a superior palpebral fold, known as the double-eyelid operation (Blepharoplasty), has become the most popular cosmetic surgery in Asia. One of the distinguishing features between an individual of Asian descent and western descent is the absence or presence of an upper eyelid crease. An eye with a double-eyelid looks fresh, youthful, and attractive. Several techniques to create a unique esthetic kind of double eyelid in the Asian population has been reported. Aims: Keeping up with the recent evolving techniques, our study is designed to study the role of removal of pretarsal tissue in Asian Blepharoplasty and to analyze the esthetic outcome. Materials and Methods: Study Variables used were age, sex, address, maximum crease height, height of eyebrow, intercanthal distance, and interpupillary distance. Outcome Measures were symmetry of both the eyelid crease and subjective aesthetic appearance. Settings and Design: An interventional prospective study was a tertiary hospital setup in Manipur, India, or a period of 2 years. Double-eyelid operation (Blepharoplasty) was performed on a total of 91 cases, with removal of pretarsal tissues along with a strip of pretarsal orbicularis oculi. Statistical Analysis: The data analyzed with IBM SPSS Statistics 21 developer. Descriptive statistics mean were used for statistical analysis and paired t-test for quantitative data. Results: A total of 91 operated cases were analyzed, taking variables - age, sex, address, maximum crease height, height of eyebrow, intercanthal distance, and interpupillary distance. Outcome measures were symmetry of both the eyelid crease and subjective esthetic appearance. It was found out that majority of the crease height remain unchanged from the intraoperative marking level. Making the preoperative planning a reliable representation of final outcome, and 76 cases (83.5%) were in Grade I subjective esthetic outcome and only 1 case was in Grade III (unsatisfied). Conclusion: Remove the pretarsal connective tissue and part of orbicularis muscle allowed for better fixation, smooth skin surface and leaving less tissue to become postoperatively edematous. Along with minimal fat excision helps to avoid a sunken sulcus. This technique gives good esthetic outcome. The procedure makes the newly created double-eyelid appear natural and more beautiful after complete recovery.
背景:创造上睑褶皱的手术,被称为双眼皮手术(眼睑成形术),已成为亚洲最流行的整容手术。亚洲人和西方人的区别特征之一是上眼睑是否有皱褶。双眼皮的眼睛看起来清新、年轻、迷人。据报道,有几种技术可以在亚洲人群中创造出独特的审美双眼皮。目的:为了跟上最新发展的技术,我们的研究旨在研究睑前组织去除在亚洲睑成形术中的作用,并分析其美学效果。材料与方法:研究变量为年龄、性别、住址、最大折痕高度、眉高、眉间距离、瞳间距离。结果测量眼睑折痕的对称性和主观审美外观。背景和设计:一项前瞻性干预性研究是在印度曼尼普尔的一家三级医院进行的,研究时间为2年。本组共91例患者行眼睑成形术,切除睑前组织及睑前眼轮匝肌条。统计分析:使用IBM SPSS Statistics 21开发人员分析数据。统计分析采用描述性统计均数,定量资料采用配对t检验。结果:以年龄、性别、住址、最大折痕高度、眉高、眉间距离、瞳间距离为变量,对91例手术病例进行分析。结果测量眼睑折痕的对称性和主观审美外观。发现大部分折痕高度与术中标记水平保持不变。术前规划是最终结果的可靠代表,76例(83.5%)主观美学结果为I级,仅1例为III级(不满意)。结论:切除跗骨前结缔组织及部分轮匝肌,使其固定效果更好,皮肤表面光滑,术后水肿组织减少。少量脂肪切除有助于避免凹陷的沟。这种技术具有良好的审美效果。该手术使新造的双眼皮在完全恢复后看起来更自然、更漂亮。
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引用次数: 0
Sigmoid volvulus in a child: An uncommon presentation of Hirschsprung disease 儿童乙状结肠扭转:先天性巨结肠的罕见表现
Q4 Medicine Pub Date : 2020-05-01 DOI: 10.4103/jms.jms_27_20
Akhilesh Kumar, Gaurav Shandilya, A. Pandey, Archika Gupta
Sigmoid volvulus (SV) is a rare cause of intestinal obstruction in childhood, and it is very uncommon below the age of 20 years and above 70 years. In childhood, SV comprises 4% of all intestinal volvulus. Hirschsprung disease (HD) is a developmental disorder of the enteric nervous system, which is characterized by the absence of ganglion cells in the myenteric and Meissner plexus; rarely, SV may complicate HD. We treated one such patient. Being extremely rare, this association is being reported with a review of the relevant literature.
乙状结肠扭转(SV)是儿童肠梗阻的一种罕见原因,在20岁以下和70岁以上的儿童中非常罕见。在儿童时期,SV占所有肠扭转的4%。先天性巨结肠(HD)是一种肠神经系统发育障碍,其特征是肌间和迈斯纳神经丛缺乏神经节细胞;SV很少会使HD复杂化。我们治疗了一个这样的病人。这种关联极为罕见,目前正在对相关文献进行综述。
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引用次数: 0
Compulsory licensing of patents and its effect on competition 专利强制许可及其对竞争的影响
Q4 Medicine Pub Date : 2020-05-01 DOI: 10.4103/jms.jms_45_20
Ruchika Ghosh
Various countries have engaged in serious re-examinations of the legal regimes they use to support innovation in recent times. This is partly due to the establishment of the World Trade Organization and its adoption of the Trade-Related Aspects of Intellectual Property Rights (TRIPS) Agreement. TRIPS made it necessary for revision of most national intellectual property laws. Patentable subject matter is defined in such a manner that protection cannot be granted for “Discoveries”. For eg. Advances such as any abstract principles of science, the fundamental relationship between energy and mass, any living organism, etc. An application for a patent must involve an “invention”. Competition law, on the other hand, aims at promoting competition as a means of market response and consumer preference so as to ensure effective and efficient allocation of resources and to create an incentive for the economy for innovation. The cost and availability of patented drugs is a key development issue, directly impacted by various government policies that affect the degree of competition. A compulsory license provides that the owner of a patent licenses the use of their rights against payment either set by law or determined through some form of adjudication or arbitration. This might be a solution to balance the two competing interests between intellectual property rights and competition law. This article will be especially useful to legal practitioners as well as pharmaceutical companies. These companies need to be aware of the laws of the land while manufacturing and marketing their drugs. They also need to be mindful of the exceptions existing in the law relating to pharmaceutical patents. This article will also be useful to Competition Lawyers in various jurisdictions.
近年来,许多国家都在认真地重新审查它们用来支持创新的法律制度。这在一定程度上是由于世界贸易组织的成立及其通过了《与贸易有关的知识产权协定》。与贸易有关的知识产权使大多数国家必须修订知识产权法。可授予专利的主题是这样定义的,即不能对“发现”给予保护。如。诸如任何抽象的科学原理、能量和质量之间的基本关系、任何活的有机体等方面的进步。一项专利申请必须包含一项“发明”。另一方面,竞争法的目的是促进竞争,作为市场反应和消费者偏好的手段,以确保有效和高效地分配资源,并为经济创新创造动力。专利药物的成本和可得性是一个关键的发展问题,直接受到影响竞争程度的各种政府政策的影响。强制许可规定专利所有人许可使用其权利,而不支付法律规定的或通过某种形式的裁决或仲裁确定的费用。这可能是平衡知识产权和竞争法之间两种相互竞争的利益的解决方案。本文对法律从业人员和制药公司特别有用。这些公司在生产和销售药品时需要了解当地的法律。他们还需要注意与药品专利有关的法律中存在的例外情况。本文对不同司法管辖区的竞争法律师亦有帮助。
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引用次数: 0
Serum lipase amylase ratio in predicting the etiology of acute pancreatitis 血清脂肪酶-淀粉酶比值预测急性胰腺炎病因
Q4 Medicine Pub Date : 2020-05-01 DOI: 10.4103/jms.jms_121_20
H. Singh, L. Singh, Priyadarshini Shougrakpam
Background: Acute pancreatitis remains a major cause of significant morbidity and mortality. Alcoholism and biliary tract stone disease are the main causes in up to 80% of cases. The diagnosis of acute pancreatitis is based on the correlation of clinical, biochemical, and radiological criteria. Serum lipase and amylase have been used to diagnose acute pancreatitis with values greater than three times the upper limit of normal being diagnostic. Objective: The aim is to study the value of serum lipase: amylase ratio in predicting the etiology of acute pancreatitis. Materials and Methods: This prospective study was conducted in a tertiary care hospital in North-East India during a 2-year period. The serum lipase/amylase ratio has been evaluated in 52 patients (31 acute alcoholic pancreatitis, 19 acute gallstone pancreatitis, 2 idiopathic). Results: Analysis of data showed that patients with acute alcoholic pancreatitis had higher serum lipase levels (2722.5 ± 285.7, mean ± standard deviation) compared to acute gallstone pancreatitis (1565.21 ± 198.2). On the other hand, acute gallstone pancreatitis patients had higher serum amylase (862.3 ± 105.5) compared to acute alcoholic pancreatitis patients (683.03 ± 618.31). Determination of lipase: amylase ratio showed that out of 31 patients of acute alcoholic pancreatitis 22 patients (71%) had lipase: amylase ratio ≥3. Out of 19 patients of acute gallstone pancreatitis, 17 patients (89.5%) had lipase: amylase ratio <3, which was found to be statistically significant. Conclusion: Serum lipase: amylase ratio fixed at 3.0 can assist in differentiating acute biliary pancreatitis from acute alcoholic pancreatitis. The lipase: amylase ratio ≥3 is observed in alcoholic acute pancreatitis while biliary pancreatitis has ratio <3.
背景:急性胰腺炎仍然是造成严重发病率和死亡率的主要原因。酒精中毒和胆道结石是高达80%的病例的主要原因。急性胰腺炎的诊断是基于临床、生化和放射学标准的相关性。血清脂肪酶和淀粉酶已被用于诊断急性胰腺炎,其值是正常诊断上限的三倍以上。目的:探讨血清脂肪酶与淀粉酶比值在预测急性胰腺炎病因中的价值。材料和方法:这项前瞻性研究在印度东北部的一家三级护理医院进行,为期2年。对52例患者(31例急性酒精性胰腺炎,19例急性胆结石性胰腺炎,2例特发性胰腺炎)的血清脂肪酶/淀粉酶比值进行了评估。结果:急性酒精性胰腺炎患者血清脂肪酶水平(2722.5±285.7,平均值±标准差)高于急性胆源性胰腺炎(1565.21±198.2),急性胆源性胰腺炎患者血清淀粉酶(862.3±105.5)高于急性酒精性胰腺炎患者(683.03±618.31)。脂肪酶:淀粉酶比值测定显示,31例急性酒精性肝炎患者中,22例(71%)脂肪酶:淀粉酶≥3。在19例急性胆源性胰腺炎患者中,17例(89.5%)患者的脂肪酶:淀粉酶比率<3,这一结果具有统计学意义。结论:血清脂肪酶与淀粉酶比值固定在3.0有助于鉴别急性胆源性胰腺炎和急性酒精性胰腺炎。酒精性急性胰腺炎的脂肪酶与淀粉酶比值≥3,胆源性胰腺炎的比值<3。
{"title":"Serum lipase amylase ratio in predicting the etiology of acute pancreatitis","authors":"H. Singh, L. Singh, Priyadarshini Shougrakpam","doi":"10.4103/jms.jms_121_20","DOIUrl":"https://doi.org/10.4103/jms.jms_121_20","url":null,"abstract":"Background: Acute pancreatitis remains a major cause of significant morbidity and mortality. Alcoholism and biliary tract stone disease are the main causes in up to 80% of cases. The diagnosis of acute pancreatitis is based on the correlation of clinical, biochemical, and radiological criteria. Serum lipase and amylase have been used to diagnose acute pancreatitis with values greater than three times the upper limit of normal being diagnostic. Objective: The aim is to study the value of serum lipase: amylase ratio in predicting the etiology of acute pancreatitis. Materials and Methods: This prospective study was conducted in a tertiary care hospital in North-East India during a 2-year period. The serum lipase/amylase ratio has been evaluated in 52 patients (31 acute alcoholic pancreatitis, 19 acute gallstone pancreatitis, 2 idiopathic). Results: Analysis of data showed that patients with acute alcoholic pancreatitis had higher serum lipase levels (2722.5 ± 285.7, mean ± standard deviation) compared to acute gallstone pancreatitis (1565.21 ± 198.2). On the other hand, acute gallstone pancreatitis patients had higher serum amylase (862.3 ± 105.5) compared to acute alcoholic pancreatitis patients (683.03 ± 618.31). Determination of lipase: amylase ratio showed that out of 31 patients of acute alcoholic pancreatitis 22 patients (71%) had lipase: amylase ratio ≥3. Out of 19 patients of acute gallstone pancreatitis, 17 patients (89.5%) had lipase: amylase ratio <3, which was found to be statistically significant. Conclusion: Serum lipase: amylase ratio fixed at 3.0 can assist in differentiating acute biliary pancreatitis from acute alcoholic pancreatitis. The lipase: amylase ratio ≥3 is observed in alcoholic acute pancreatitis while biliary pancreatitis has ratio <3.","PeriodicalId":39636,"journal":{"name":"JMS - Journal of Medical Society","volume":"34 1","pages":"96 - 100"},"PeriodicalIF":0.0,"publicationDate":"2020-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43407561","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Determination of hepatitis C viral load and human immunodeficiency virus 1 RNA viral load and their correlation with CD4 cell count in human immunodeficiency virus and hepatitis C virus coinfected patients attending a tertiary care hospital in Northeast India 印度东北部三级医院丙型肝炎病毒和丙型肝炎病毒合并感染患者丙型肝炎病毒载量和人类免疫缺陷病毒1 RNA病毒载量的测定及其与CD4细胞计数的相关性
Q4 Medicine Pub Date : 2020-05-01 DOI: 10.4103/jms.jms_33_20
Krossnunpuii, H. Singh, Kshetrimayum Singh
Background: Human immunodeficiency virus (HIV)–hepatitis C virus (HCV) coinfection is common due to their shared routes of transmission. Coinfected persons have a higher mortality rate. Some investigators reported an inverse correlation between hepatitis C viral load and CD4 cell count, whereas others have found no such correlation. Objectives: The objectives of the study were to determine hepatitis C viral load, HIV1 RNA viral load, and CD4 cell count and to find the correlation between hepatitis C viral load, HIV1 RNA viral load, and CD4 cell count in HIV-HCV coinfected patients. Materials and Methods: A cross-sectional study conducted in RIMS Hospital, Manipur, between September 2016 and August 2018 among 52 HIV and HCV coinfected patients. Hepatitis C viral load and HIV1 RNA viral load were measured using COBAS® TaqMan® HCV Test and COBAS® TaqMan® HIV-1 test, respectively. COBAS® TaqMan® 48 Analyzer was used for automated amplification and detection. BD fluorescent-activated cell sorter count machine was used for CD4 cell count. Results: Majority of the subjects were male and in the age group of 15–49 years. The most common mode of infection was injecting drug use. There was a statistically insignificant weak negative correlation between hepatitis C viral load and HIV1 RNA viral load, hepatitis C viral load and CD4 cell count, and HIV1 RNA viral load and CD4 cell count. Conclusion: This study found no correlation between hepatitis C viral load and CD4 cell count, HIV1 RNA viral load and hepatitis C viral load, and HIV1 RNA viral load and CD4 cell count. Along with the free antiretroviral therapy treatment made available, there is a need for strategies to rapidly diagnose HCV infection in HIV-HCV coinfected patients and enhance HCV treatment uptake so as to prevent HCV-related morbidity and mortality in these patients.
背景:人类免疫缺陷病毒(HIV)-丙型肝炎病毒(HCV)的共同感染是常见的,因为它们有共同的传播途径。共感染者的死亡率较高。一些研究人员报告了丙型肝炎病毒载量和CD4细胞计数之间的负相关,而其他人则没有发现这种相关性。目的:本研究的目的是确定丙型肝炎病毒载量、HIV-1RNA病毒载量和CD4细胞计数,并找出HIV-HCV共感染患者的丙型肝炎病毒负载量、HIV1RNA病毒载量与CD4细胞数之间的相关性。材料和方法:2016年9月至2018年8月在曼尼普尔RIMS医院对52名HIV和HCV共感染患者进行的横断面研究。丙型肝炎病毒载量和HIV1 RNA病毒载量分别使用COBAS®TaqMan®HCV测试和COBAS®TaqMan™HIV-1测试进行测量。COBAS®TaqMan®48分析仪用于自动扩增和检测。BD荧光活化细胞分选机用于CD4细胞计数。结果:大多数受试者为男性,年龄在15-49岁之间。最常见的感染方式是注射吸毒。丙型肝炎病毒载量与HIV1核糖核酸病毒载量、丙型肝炎病毒负载量与CD4细胞计数、HIV1核糖核糖核酸病毒负载量和CD4细胞数之间存在统计学上不显著的弱负相关。结论:本研究未发现丙型肝炎病毒载量与CD4细胞计数、HIV1 RNA病毒载量和丙型肝炎病毒载荷、HIV1核糖核酸病毒载量及CD4细胞数之间存在相关性。除了提供免费的抗逆转录病毒治疗外,还需要制定策略来快速诊断HIV-HCV共感染患者的HCV感染,并提高HCV治疗的接受率,以预防这些患者中与HCV相关的发病率和死亡率。
{"title":"Determination of hepatitis C viral load and human immunodeficiency virus 1 RNA viral load and their correlation with CD4 cell count in human immunodeficiency virus and hepatitis C virus coinfected patients attending a tertiary care hospital in Northeast India","authors":"Krossnunpuii, H. Singh, Kshetrimayum Singh","doi":"10.4103/jms.jms_33_20","DOIUrl":"https://doi.org/10.4103/jms.jms_33_20","url":null,"abstract":"Background: Human immunodeficiency virus (HIV)–hepatitis C virus (HCV) coinfection is common due to their shared routes of transmission. Coinfected persons have a higher mortality rate. Some investigators reported an inverse correlation between hepatitis C viral load and CD4 cell count, whereas others have found no such correlation. Objectives: The objectives of the study were to determine hepatitis C viral load, HIV1 RNA viral load, and CD4 cell count and to find the correlation between hepatitis C viral load, HIV1 RNA viral load, and CD4 cell count in HIV-HCV coinfected patients. Materials and Methods: A cross-sectional study conducted in RIMS Hospital, Manipur, between September 2016 and August 2018 among 52 HIV and HCV coinfected patients. Hepatitis C viral load and HIV1 RNA viral load were measured using COBAS® TaqMan® HCV Test and COBAS® TaqMan® HIV-1 test, respectively. COBAS® TaqMan® 48 Analyzer was used for automated amplification and detection. BD fluorescent-activated cell sorter count machine was used for CD4 cell count. Results: Majority of the subjects were male and in the age group of 15–49 years. The most common mode of infection was injecting drug use. There was a statistically insignificant weak negative correlation between hepatitis C viral load and HIV1 RNA viral load, hepatitis C viral load and CD4 cell count, and HIV1 RNA viral load and CD4 cell count. Conclusion: This study found no correlation between hepatitis C viral load and CD4 cell count, HIV1 RNA viral load and hepatitis C viral load, and HIV1 RNA viral load and CD4 cell count. Along with the free antiretroviral therapy treatment made available, there is a need for strategies to rapidly diagnose HCV infection in HIV-HCV coinfected patients and enhance HCV treatment uptake so as to prevent HCV-related morbidity and mortality in these patients.","PeriodicalId":39636,"journal":{"name":"JMS - Journal of Medical Society","volume":"34 1","pages":"81 - 85"},"PeriodicalIF":0.0,"publicationDate":"2020-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43945888","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Measures to contain the coronavirus disease 2019 pandemic in workplace settings: Public health perspective 在工作场所遏制2019冠状病毒病大流行的措施:公共卫生视角
Q4 Medicine Pub Date : 2020-05-01 DOI: 10.4103/jms.jms_22_20
S. Shrivastava, P. Shrivastava
The ongoing global coronavirus disease-2019 (COVID-19) outbreak has been declared as a pandemic, a public health emergency of international concern, and also as a disease which has shown a very high risk of global transmission. The available evidence suggests that the disease is being transmitted through close contacts or through droplets and thus the probability of acquiring the infection at workplace becomes very high, wherein a group of people work in constrained settings. This calls for the need to implement specific measures to minimize the probability of acquisition of infection. In order to prevent the spread of COVID-19 in the workplace, it is a must that it should be kept clean and hygienic and practices to promote better respiratory hygiene and hand hygiene should be envisaged. Further, specific interventions should be taken to improve the mental health of the employees by supporting them to alleviate their fear and anxiety associated with the disease. In conclusion, the effective containment of the COVID-19 pandemic requires a multisectoral approach and thus, we have to get our workplace ready and ensure the safety of the employees and be together in our battle against the novel infection.
正在进行的2019冠状病毒病(COVID-19)全球疫情已被宣布为大流行,是国际关注的突发公共卫生事件,也是一种显示出极高全球传播风险的疾病。现有证据表明,该疾病是通过密切接触或飞沫传播的,因此在工作场所感染的可能性非常高,其中一群人在受限的环境中工作。这就要求采取具体措施,尽量减少感染的可能性。为了防止COVID-19在工作场所传播,必须保持工作场所的清洁和卫生,并应设想促进更好的呼吸卫生和手卫生的做法。此外,应采取具体的干预措施,通过支持员工减轻与该疾病有关的恐惧和焦虑,改善员工的心理健康。总之,有效遏制COVID-19大流行需要采取多部门方法,因此,我们必须做好工作场所的准备,确保员工的安全,并共同抗击新型感染。
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引用次数: 0
Seroprevalence and seroconversion rates of human immunodeficiency virus discordant couples attending a tertiary care center: A prospective cohort study 参加三级保健中心的人类免疫缺陷病毒不一致夫妇的血清阳性率和血清转化率:一项前瞻性队列研究
Q4 Medicine Pub Date : 2020-05-01 DOI: 10.4103/jms.jms_52_20
K. Arjun Bal, L. Singh, S. Singh, Manna Bhattacharjee, N. Singh, S. Rai, Namanandi Ashwini, Phillip Laishram
Background: Serodiscordant couples are an important population group that needs to be addressed in human immunodeficiency virus (HIV) prevention. However, the exact magnitude of the problem is often underestimated even among health care workers. Methods: This prospective cohort study was conducted in the Regional Institute of Medical Sciences, Imphal for a period of 2 years, to estimate the prevalence and seroconversion rates of HIV discordant couples in this population. Results: Among the 90 discordant couples under follow-up, 2 HIV-negative partners seroconverted with a seroconversion rate of 1.14 hundred person-years. The average age of the study population was 36.99 years. Eighty percent of the HIV positive partners were males Seventy-six out of 90 patients were educated at primary school level and above. Intravenous drug use was the main risk factor.
背景:血清不和谐夫妇是人类免疫缺陷病毒(HIV)预防中需要关注的重要人群。然而,即使在卫生保健工作者中,问题的确切程度也常常被低估。方法:这项前瞻性队列研究在英帕尔地区医学科学研究所进行了为期2年的研究,以估计该人群中HIV不一致夫妇的患病率和血清转化率。结果:在随访的90对不一致夫妇中,有2对hiv阴性伴侣血清转化,血清转化率为1.14万人年。研究人群的平均年龄为36.99岁。80%的艾滋病毒阳性伴侣是男性,90名患者中有76人受过小学及以上教育。静脉吸毒是主要的危险因素。
{"title":"Seroprevalence and seroconversion rates of human immunodeficiency virus discordant couples attending a tertiary care center: A prospective cohort study","authors":"K. Arjun Bal, L. Singh, S. Singh, Manna Bhattacharjee, N. Singh, S. Rai, Namanandi Ashwini, Phillip Laishram","doi":"10.4103/jms.jms_52_20","DOIUrl":"https://doi.org/10.4103/jms.jms_52_20","url":null,"abstract":"Background: Serodiscordant couples are an important population group that needs to be addressed in human immunodeficiency virus (HIV) prevention. However, the exact magnitude of the problem is often underestimated even among health care workers. Methods: This prospective cohort study was conducted in the Regional Institute of Medical Sciences, Imphal for a period of 2 years, to estimate the prevalence and seroconversion rates of HIV discordant couples in this population. Results: Among the 90 discordant couples under follow-up, 2 HIV-negative partners seroconverted with a seroconversion rate of 1.14 hundred person-years. The average age of the study population was 36.99 years. Eighty percent of the HIV positive partners were males Seventy-six out of 90 patients were educated at primary school level and above. Intravenous drug use was the main risk factor.","PeriodicalId":39636,"journal":{"name":"JMS - Journal of Medical Society","volume":"9 1","pages":"91 - 95"},"PeriodicalIF":0.0,"publicationDate":"2020-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70807332","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparison of 3% saline versus normal saline as a diluent for nebulization in hospitalized children with acute bronchiolitis: A randomized clinical trial 3%生理盐水与生理盐水雾化吸入治疗急性毛细支气管炎住院儿童的比较:一项随机临床试验
Q4 Medicine Pub Date : 2020-05-01 DOI: 10.4103/jms.jms_43_20
Lalrammuana Hmar, Sarita Brahmacharimayum, Namganglung Golmei, M. Moirangthem, Shyamsunder Chongtham
Context: Bronchiolitis, the most common lower respiratory tract infection among infants and young children, is managed with a few clinically beneficial interventions. Hypertonic saline (HS) nebulization is suggested in the treatment of bronchiolitis, resulting in clinical improvement. Aim: The aim of the study was to compare the efficacy 3% HS versus 0.9% normal saline (NS) as nebulization diluent in children between 3 months and 2 years with acute bronchiolitis. Materials and Methods: In this prospective randomized controlled study, 158 admitted children between 3 months and 2 years with acute bronchiolitis were assigned into two groups – 3% HS and NS. Outcome variables were improvement in clinical severity (CS) score and length of hospital stay (LOS). Descriptive statistics such as mean, median, standard deviation, and percentages were used. Chi-square and t-tests were used to determine associations. Data analysis was performed using SPSS IBM version 21. Results: Baseline CS scores were similar – 3.98 ± 1.20 and 3.75 ± 1.06 for HS and NS groups (P = 0.209), respectively, but from the 2nd day of treatment, it decreased to 2.21 ± 1.10 for HS and 3.05 ± 1.17 for NS group (P ≤ 0.001), further reducing to 1.46 ± 0.63 for HS group and 2.01 ± 0.99 for NS group (P ≤ 0.001). Length of stay was also reduced: 4.98 ± 1.35 for the HS group compared to 5.84 ± 1.18 for the NS group (P ≤ 0.001). Conclusion: Using 3% HS instead of NS as a diluent for nebulization decreases clinical symptoms acute bronchiolitis besides the length of hospital stay.
背景:毛细支气管炎是婴幼儿中最常见的下呼吸道感染,通过一些临床有益的干预措施进行治疗。高渗生理盐水(HS)雾化治疗细支气管炎,疗效显著。目的:本研究的目的是比较3% HS与0.9%生理盐水(NS)作为雾化器稀释剂对3个月至2岁急性毛细支气管炎患儿的疗效。材料和方法:在这项前瞻性随机对照研究中,158名3个月至2岁的急性细支气管炎患儿被分为两组:3% HS组和3% NS组。结果变量为临床严重程度(CS)评分和住院时间(LOS)的改善。使用了描述性统计,如平均值、中位数、标准差和百分比。采用卡方检验和t检验确定相关性。使用SPSS IBM version 21进行数据分析。结果:HS组和NS组的CS基线评分相似,分别为3.98±1.20和3.75±1.06 (P = 0.209),但从治疗第2天开始,HS组CS基线评分分别降至2.21±1.10和3.05±1.17 (P≤0.001),HS组CS基线评分进一步降至1.46±0.63和2.01±0.99 (P≤0.001)。HS组的住院时间为4.98±1.35,NS组为5.84±1.18 (P≤0.001)。结论:用3% HS代替NS作为稀释剂雾化治疗急性毛细支气管炎,可减少临床症状,缩短住院时间。
{"title":"Comparison of 3% saline versus normal saline as a diluent for nebulization in hospitalized children with acute bronchiolitis: A randomized clinical trial","authors":"Lalrammuana Hmar, Sarita Brahmacharimayum, Namganglung Golmei, M. Moirangthem, Shyamsunder Chongtham","doi":"10.4103/jms.jms_43_20","DOIUrl":"https://doi.org/10.4103/jms.jms_43_20","url":null,"abstract":"Context: Bronchiolitis, the most common lower respiratory tract infection among infants and young children, is managed with a few clinically beneficial interventions. Hypertonic saline (HS) nebulization is suggested in the treatment of bronchiolitis, resulting in clinical improvement. Aim: The aim of the study was to compare the efficacy 3% HS versus 0.9% normal saline (NS) as nebulization diluent in children between 3 months and 2 years with acute bronchiolitis. Materials and Methods: In this prospective randomized controlled study, 158 admitted children between 3 months and 2 years with acute bronchiolitis were assigned into two groups – 3% HS and NS. Outcome variables were improvement in clinical severity (CS) score and length of hospital stay (LOS). Descriptive statistics such as mean, median, standard deviation, and percentages were used. Chi-square and t-tests were used to determine associations. Data analysis was performed using SPSS IBM version 21. Results: Baseline CS scores were similar – 3.98 ± 1.20 and 3.75 ± 1.06 for HS and NS groups (P = 0.209), respectively, but from the 2nd day of treatment, it decreased to 2.21 ± 1.10 for HS and 3.05 ± 1.17 for NS group (P ≤ 0.001), further reducing to 1.46 ± 0.63 for HS group and 2.01 ± 0.99 for NS group (P ≤ 0.001). Length of stay was also reduced: 4.98 ± 1.35 for the HS group compared to 5.84 ± 1.18 for the NS group (P ≤ 0.001). Conclusion: Using 3% HS instead of NS as a diluent for nebulization decreases clinical symptoms acute bronchiolitis besides the length of hospital stay.","PeriodicalId":39636,"journal":{"name":"JMS - Journal of Medical Society","volume":"34 1","pages":"86 - 90"},"PeriodicalIF":0.0,"publicationDate":"2020-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47207552","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
A study of relationship between maternal serum vitamin D levels during pregnancy and risk of preterm births 孕妇孕期血清维生素D水平与早产风险关系的研究
Q4 Medicine Pub Date : 2020-01-01 DOI: 10.4103/jms.jms_50_20
G. Dhillon, Suneeta Singh, H. Dhillon, S. Sasidharan
Background: Preterm birth is the leading cause of death among neonates and children under 5 years of age with long-term adverse sequelae in the survivors. Vitamin D is being increasingly researched for its protective effect against the risk for preterm births due to its role in immunomodulatory and anti-inflammatory processes. An observational study was undertaken to study the relationship between maternal serum Vitamin D levels during peripartum period and the risk for preterm birth. Materials and Methods: This study employed a cross sectional design in a tertiary care center on 569 patients to study the relationship between maternal serum Vitamin D levels and risk of preterm births. Results: A total of 569 samples of maternal and neonatal serum were analyzed for serum 25-hydroxyvitamin D (25[OH]D) levels. Four hundred and sixty-four (81.54%) mothers had Vitamin D sufficient (VDS) levels ≥30 ng/ml and 105 (18.45%) had Vitamin D deficient (VDD) levels <30 ng/ml. Out of the total 569 deliveries, 501 (88.04%) occurred at term (≥37 weeks' period of gestation) and 68 (11.95%) were preterm (<37 weeks' period of gestation). The incidence of preterm births was 10.77% in the VDS group as compared to 17.14% in the VDD group (P = 0.038). The mean cord blood 25(OH) D level of preterm neonates was 12.68 ng/ml (standard deviation [SD] 3.85, range 7.9–22) and term neonates was 13.63 ng/ml (SD 3.76, range 8.2–27) (P = 0.035). Conclusion: The rate of preterm delivery was 1.59 times higher in mothers with Vitamin D deficiency. Furthermore, the mean cord blood Vitamin D levels were higher in term newborns.
背景:早产是新生儿和5岁以下儿童死亡的主要原因,幸存者有长期不良后遗症。由于维生素D在免疫调节和抗炎过程中的作用,人们越来越多地研究它对早产风险的保护作用。进行了一项观察性研究,以研究产妇围产期血清维生素D水平与早产风险之间的关系。材料和方法:本研究在一家三级护理中心对569名患者进行了横断面设计,以研究母体血清维生素D水平与早产风险之间的关系。结果:对569份孕产妇和新生儿血清样本进行了血清25-羟基维生素D(25[OH]D)水平分析。4664名(81.54%)母亲的维生素D充足(VDS)水平≥30 ng/ml,105名(18.45%)母亲维生素D缺乏(VDD)水平<30 ng/ml。在总共569次分娩中,501次(88.04%)发生在足月(妊娠期≥37周),68次(11.95%)早产(妊娠期<37周)。VDS组的早产发生率为10.77%,而VDD组为17.14%(P=0.038)。早产儿的平均脐血25(OH)D水平为12.68 ng/ml(标准差[SD]3.85,范围7.9-22),足月新生儿为13.63 ng/ml(SD 3.76,范围8.2-27)(P=0.035)缺乏此外,足月新生儿的平均脐血维生素D水平较高。
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引用次数: 0
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JMS - Journal of Medical Society
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