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Analysis and Knowledge of Blood Groups and Attitudes Toward Blood Donation in Jordan 约旦血型及献血态度的分析与认识
Q4 Medicine Pub Date : 2022-07-31 DOI: 10.35516/jmj.v56i1.223
Ahmad Alkhataybeh, Banan Alkhataybeh
Background: This study aimed to determine the distribution of blood groups among Jordanian university students, investigate the Knowledge and attitudes toward blood donation among the study population. Also, it aimed at assessing any correlation between blood groups and achievement, geographical distribution, and gender. As well as, it aimed to investigate the personal Knowledge of blood group, the blood donations throughout life, matching of blood group compared to those registered in the governmental departments, ability to form a database of people who can donate blood.Methods: To attain the study's objective, a random sample of 830 Jordanian university students from different regions were selected. The researcher adopted an analytical and descriptive study.Results: The study revealed that the most prominent blood group among Jordanian university students is A group according to the ABO system and group O+ according to ABO and RH system. Also, it revealed that 93.6% had not donated blood.Conclusions: Blood group A was found to be the highest among the study population. 81.2% of the students were found to be RH+. Recording blood groups correctly and encouraging blood donation in the Jordanian community is critical for life-saving.
背景:本研究旨在确定约旦大学生的血型分布,调查研究人群对献血的知识和态度。此外,它还旨在评估血型与成就、地理分布和性别之间的相关性。此外,它还旨在调查个人对血型的了解情况,一生的献血情况,与政府部门登记的血型的匹配情况,以及形成献血者数据库的能力。方法:为达到研究目的,随机抽取来自不同地区的约旦大学生830名。研究者采用了分析性和描述性的研究方法。结果:研究显示,约旦大学生中最突出的血型是ABO系统的A血型和ABO和RH系统的O+血型。此外,调查还显示,93.6%的人没有献血。结论:A型血在研究人群中发病率最高。81.2%的学生RH+。在约旦社区正确记录血型并鼓励献血对挽救生命至关重要。
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引用次数: 0
Nitrous Oxide Inhalation Sedation in Pediatric Dentistry: An overview of the available guidelines 儿童牙科中的一氧化二氮吸入镇静:现有指南综述
Q4 Medicine Pub Date : 2022-07-31 DOI: 10.35516/jmj.v56i2.239
D. Ibrahim
Children with behavioral issues are usually inadequately treated using non-pharmacological behavior management techniques, making dental treatment a real clinical challenge for the practitioner. This leads to the indispensable need for advanced pharmacological techniques, such as inhalation sedation (IS). In pediatric dentistry, nitrous oxide sedation is considered the safest tool for a dental practitioner to use on uncooperative children, thus reducing the need for dental treatment under general anesthesia. To date, several sets of high-ranking evidence-based inhalation sedation guidelines are available,developed in the United States, United Kingdom, Europe, Australia, and New Zealand. This review summarizes the indications, contraindications, advantages, and disadvantages of using nitrous oxide sedation in children, and compares these in terms of inhalation sedation procedure and documentation. This review will assist the dental practitioner in developing appropriate practice regulations for safe and effective practice.
有行为问题的儿童通常没有充分使用非药物行为管理技术进行治疗,这使得牙科治疗对医生来说是一个真正的临床挑战。这导致了对先进药理学技术的必要需求,如吸入镇静(IS)。在儿科牙科中,一氧化二氮镇静被认为是牙科医生对不合作儿童使用的最安全的工具,从而减少了在全身麻醉下进行牙科治疗的需要。到目前为止,美国、英国、欧洲、澳大利亚和新西兰已经制定了几套高级循证吸入镇静指南。这篇综述总结了在儿童中使用一氧化二氮镇静的适应症、禁忌症、优点和缺点,并从吸入镇静程序和文献方面进行了比较。这项审查将帮助牙科医生制定适当的执业法规,以确保安全有效的执业。
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引用次数: 0
Prevalence and Predictors of Irritable Bowel Syndrome among Medical Students 医学生肠易激综合征的患病率及预测因素
Q4 Medicine Pub Date : 2022-07-31 DOI: 10.35516/jmj.v56i1.231
Randa I. Farah, Nadia Khamis, Awni T. Abu Sneineh, Aseil Khatib, Sophia Haddadin, M. Darwish, Y. Rayyan
Irritable bowel syndrome (IBS) is one of the most common functional gastrointestinal disorders, and medical students are at a higher risk for this disorder, given their stressful lives. This study aims to identify the prevalence of IBS and the associated risk factors among MS. A cross-sectional study was conducted among medical students at all academic levels. Data were collected from January to September 2018 using a validated, self-administered, and anonymous questionnaire. Five hundred eighty-five students were included, and an IBS diagnosis was made in 37 students. Older students and those in higher clinical years are at greater risk for developing IBS (P <.02 and.001, respectively). The factors associated with IBS (adjusting for known confounders) included a family history of IBS [adjusted odds ratio (AOR): 7.06 (95% CI: 2.923 - 17.069)], rare use of over-the-counter pain medications, [AOR: 2.806; 95% CI: 0.004-0.431; P <.003] and students experiencing high levels ofanxiety [AOR : 3.33 (95% CI: 1.392 -7.981); P<.002]. In this study, the risk of IBS among medical students was 6.6%.
肠易激综合征(IBS)是最常见的功能性胃肠道疾病之一,鉴于医学生的生活压力很大,他们患这种疾病的风险更高。本研究旨在确定多发性硬化症中IBS的患病率和相关风险因素。在所有学术水平的医学生中进行了一项横断面研究。数据收集于2018年1月至9月,使用经过验证的、自我管理的匿名问卷。五百八十五名学生被纳入研究,37名学生被诊断为肠易激综合征。年龄较大的学生和临床年龄较高的学生患IBS的风险更大(分别为P<.02和.001)。与IBS相关的因素(对已知的混杂因素进行调整)包括IBS家族史[调整后的比值比(AOR):7.06(95%CI:2.923-17.069)]、罕见使用非处方止痛药[AOR:2.806;95%CI:0.004-0.431;P<.003]和经历高水平焦虑的学生[AOR:3.33(95%CI:1.392-7.981);P<.001 2]。在本研究中,医学生发生IBS的风险为6.6%。
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引用次数: 1
An Ultrastructural Perspective on Cell Death. 细胞死亡的超微结构视角
Q4 Medicine Pub Date : 2022-01-01 Epub Date: 2022-07-31 DOI: 10.35516/jmj.v56i1.232
Zaid R Najdawi, Mones S Abu-Asab

In the field of cell death, there is still a wide gap between the molecular models and their ultrastructural phenotypes. Because only very few published works included electron microscopy (EM) images, many ultrastructural features have not yet been incorporated into the descriptions of death modes. Some of the EM features that appear in dying cells have not been incorporated in describing death modes. It includes the accumulation of lipid droplets and glycogen, the appearance of extranuclear chromatin in the cytoplasm, and the various ways mitochondria become damaged. We argue that electron microscopy should be routinely included in these studies because it exposes some new features that molecular studies do not. It has successfully recognized new modes of cell death, such as entosis, methuosis, and paraptosis. Elucidating the precise sequence of events in death modes could be the cornerstone for offering the proper therapy of many diseases by slowing down or stopping the progression of degeneration. This review presents our own experience applying ultrastructural interpretations to death modes and explaining their biochemical implications. We complement the molecular and biochemical data and point out missing features that should be considered and studied.

在细胞死亡领域,分子模型与其超微结构表型之间仍有很大的差距。由于只有极少数已发表的作品包含电子显微镜(EM)图像,许多超微结构特征尚未纳入死亡模式的描述。在死亡细胞中出现的一些EM特征尚未被纳入描述死亡模式。它包括脂滴和糖原的积累,细胞质中核外染色质的出现,以及线粒体受损的各种方式。我们认为,电子显微镜应该常规纳入这些研究,因为它揭示了一些新的特征,分子研究没有。它已经成功地识别了新的细胞死亡模式,如内吞、细胞凋亡和细胞凋亡。阐明死亡模式中事件的精确顺序,可能是通过减缓或阻止退化进程,为许多疾病提供适当治疗的基石。这篇综述介绍了我们自己应用超微结构解释死亡模式和解释其生化意义的经验。我们补充了分子和生化数据,并指出了应该考虑和研究的缺失特征。
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引用次数: 3
The possible effect of Brexit on the pharmaceutical industry: Pharmacovigilance 英国脱欧对制药行业可能产生的影响:药物警戒
Q4 Medicine Pub Date : 2018-07-13 DOI: 10.4172/2329-6887-C1-032
A. Barzey
Aim: The aim of this study was to assess levels of depressive symptoms present in patients with diabetic foot. Methods: A convenience sampling method was used to recruit 108 patients with diabetic foot. After having completed the Centre for Epidemiologic Studies Depression Scale CES-D scale, the patients' demographic data and medical history were collected using pre-structured forms. Results: Of the entire sample, 38.9% have CES-D score ≥27, which indicates risk of major depression. Logistic regression analysis showed that retinopathy was significantly associated with increased depressive symptoms among diabetic foot patients (odds ratio 3.41(p=0.017)). Taking supplement therapy and not taking a combination of oral hypoglycemic agent and insulin treatment were significantly associated with higher depressive symptoms (odds ratio 3.38 (p=0.022), 2.83 (p=0.030)), respectively. Patients with primary education level have the highest odds ratio among all factors associated with risk of major depression (OR, 4.07; p=0.003). Conclusions: The risk of major deression among patients with diabetic foot in Jordan is high compared to general diabetic population. This was associated with low educational level, retinopathy, taking supplemt therapy, but not taking a combination of oral hypoglycemic agent and insulin. There is a need for routine screening for depressive symptoms in patients with diabetic foot to help in the prevention, early detection of depression and even referral to a psychiatrist.
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引用次数: 10
Shear Bond Strength of Repaired Composite Using Single Bond Adhesive 单粘结剂修复复合材料剪切粘接强度的研究
Q4 Medicine Pub Date : 2017-12-04 DOI: 10.19080/adoh.2017.06.555695
A. A. Al-Asmar, A. Sabra, F. Sawair, A. Khraisat
Objectives: The aim of this study was to evaluate the shear bond strength of repaired composite resin restorations using one-step Single Bond Universal adhesive. Materials and Methods: Sixty cylindrical composite samples (8 x 9 mm each) were prepared from Filtek Z350 XT, light-cured and stored for 6 weeks. The surface of each sample was bur-roughened and acid-etched with 37% phosphoric acid. Samples (N = 60) were randomly assigned into 2 groups. For group 1 (the control group), silane coupling agent and bonding agent were applied in two separate steps. For group 2 (the test group), Single Bond Universal adhesive containing both silane and bonding agents was applied to the surface of the samples. Fresh composite resin was bonded to treated surfaces, and samples were cured and stored for another 6 weeks. The shear bond strength (SBS) was measured and analyzed using an independent samples t-test and descriptive statistics. Stereomicroscope examination of the samples was done to assess the mode of failure between the original and the repaired composite layers for the control and test groups. Results: The mean initial failure SBS for the test group was significantly higher than that of the control group (p < 0.001). Of the control group samples, 80% failed adhesively, while 100% of the test group samples showed cohesive failure and a mixed mode of failure when observed under the stereomicroscope. Conclusion: Single Bond Universal adhesive provides more reliable bond strength for repaired composite resin restorations compared with two-step silane and bonding agent application.
目的:本研究的目的是评估使用一步单粘结通用粘合剂修复的复合树脂修复体的剪切粘结强度。材料和方法:从Filtek Z350 XT制备60个圆柱形复合材料样品(每个8 x 9mm),光固化并储存6周。对每个样品的表面进行毛刺粗糙化,并用37%的磷酸进行酸蚀刻。将样本(N=60)随机分为2组。对于第1组(对照组),在两个单独的步骤中施用硅烷偶联剂和粘合剂。对于第2组(测试组),将含有硅烷和粘合剂的Single Bond Universal粘合剂应用于样品表面。将新鲜的复合树脂粘合到处理过的表面上,并将样品固化并再储存6周。剪切结合强度(SBS)采用独立样本t检验和描述性统计进行测量和分析。对样品进行立体显微镜检查,以评估对照组和试验组原始复合层和修复复合层之间的失效模式。结果:试验组的平均初始失效SBS显著高于对照组(p<0.001)。在对照组样品中,80%的样品粘附失效,而在立体显微镜下观察时,试验组样品100%显示内聚失效和混合失效模式。结论:与两步硅烷和粘结剂的应用相比,单键通用粘结剂为复合树脂修复体提供了更可靠的粘结强度。
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引用次数: 1
Clinicopathological study of 55 cases of immunobullous diseases in Jordan 约旦55例免疫大疱性疾病的临床病理研究
Q4 Medicine Pub Date : 2017-08-01 DOI: 10.12816/0039751
A. Al-Tarawneh
Background: Immunobullous skin diseases are a serious group of skin disorders with variable presentations that need to be diagnosed early for better prognosis. A proper clinical and histopathological evaluation is needed for correct diagnosis, so it is an important issue to share experience and to highlight this hot spot in dermatology. Objective: To have a clinical and histopathological insight into the immunobullous skin diseases as a group to show their distribution in our region and to share experience for proper early diagnosis. Material and Methods: All cases of immunobullous skin diseases that had been diagnosed clinically and histopathologically at referral centers in Jordan, Amman (King Hussein Medical Center, Jordan University hospital) and in private practice from Jan. 2000 to Jan. 2012 were included in this retrospective study. All cases were analyzed clinically and histopathologically. Hematoxylin and Eosin stained sections were used for histopathological analysis. Immunoflourscence study was done on 16 cases only and Tzanck smear examination after staining with Giemsa stain was done on 5 cases. Results: From Jan. 2000 to Jan. 2012 a total number 55 cases of different immunobullous skin diseases had been diagnosed clinically and histopathologically from a total number of 2156 skin biopsies that had been performed for different reasons and examined during that period of time. There were 21 male patient and 34 female patients with M:F ratio 1.2: 2. Age range of the patients is 4-85 yr. The distribution of different immunobullous diseases in decreasing frequency was; bullous pemphigoid 24 patients (44%), Pemphigus vulgaris 14 patients (25%), Pemphigus folaceous 5 cases (9%), Pemphigoid gesatationis 4 patients (7%), dermatitis herpetiformes 3 patients (5%) chronic bullous dermatosis of childhood 2 patients (8%), pemphigus erythematosus, one patient (4%), linear IgA dermatosis, one patient (4%), and lichen planus Pemphigoides one patient (4%). Histopathological features were conclusive in most of the cases. Tazanck smear test was a helpful test in cases of pemphigus group. The study reveals a rare form of pemphigus vulgaris as pemphigus with scalp lesions only. Rare histopathological features of bullous pemphigoid including cell poor blister and festooning were also seen. Conclusion: Immunobullous skin diseases are serious skin diseases that affect all age groups. Proper clinical and histopathological examination is essentially conclusive for diagnosis. In some cases immunoflourscence study is needed for diagnosis. Simple bedside test like Tzanck smear test is helpful in some cases
背景:免疫大疱性皮肤病是一组严重的皮肤病,表现各异,需要早期诊断才能获得更好的预后。为了正确诊断,需要进行适当的临床和组织病理学评估,因此分享经验并突出这一皮肤病学热点是一个重要问题。目的:对免疫大疱性皮肤病的临床和组织病理学进行深入了解,以了解其在我们地区的分布,并分享正确早期诊断的经验。材料和方法:本回顾性研究包括2000年1月至2012年1月在约旦、安曼(约旦大学医院侯赛因国王医疗中心)转诊中心和私人诊所临床和组织病理学诊断的所有免疫大疱性皮肤病病例。对所有病例进行临床和组织病理学分析。苏木精和曙红染色切片用于组织病理学分析。仅对16例患者进行免疫荧光染色,对5例患者进行Giemsa染色后的Tzanck涂片检查。结果:从2000年1月到2012年1月,从2156例因不同原因进行的皮肤活检中,共诊断出55例不同的免疫大疱性皮肤病,并在这段时间内进行了检查。男21例,女34例,男女比例为1.2∶2。患者年龄范围为4-85岁,不同类型免疫大疱性疾病的分布频率呈下降趋势;大疱性类天疱疮24例(44%),寻常型天疱疮14例(25%。大多数病例的组织病理学特征是决定性的。Tazanck涂片检查对天疱疮组的病例有帮助。这项研究揭示了一种罕见的寻常型天疱疮,即只有头皮病变的天疱疮。大疱性类天疱疮罕见的组织病理学特征,包括细胞贫乏的水疱和花饰。结论:免疫性大疱性皮肤病是影响所有年龄组的严重皮肤病。正确的临床和组织病理学检查基本上是诊断的结论。在某些情况下,需要进行免疫荧光研究来进行诊断。在某些情况下,像Tzanck涂片检查这样的简单床边检查是有帮助的
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引用次数: 0
Mixed Epithelial Stromal Tumor of the Kidney (MESTK): A Case Report 肾脏混合性上皮间质瘤(MESTK) 1例报告
Q4 Medicine Pub Date : 2017-05-01 DOI: 10.12816/0039755
B. Ammari, M. Muheilan, Hassan A Khatatbeh, Malik Ayyad, Tareq Qsus, F. Obeidat
Mixed epithelial stromal tumor of the kidney (MESTK) is a newly introduced and rare kidney tumor subtype; approximately 100 cases have been reported. We report a case of MESTK with detailed clinicopathological findings, presented to emergency department with gross hematuria and clot retention managed by radical nephrectomy. Although MESTK are benign tumors, they cannot be distinguished from other malignant neoplasms until after nephrectomy due to lack of typical radiological features. They can cause serious sequelae; including gross hematuria and serious drop in hemoglobin as the case we present here shows. This is why it is important to early diagnose and treat this condition. This case highlights the importance of early introduction of imaging in patients presenting with gross hematuria. Failure to diagnose this lesion as the underlying cause of hematuria may lead to recurrence and malignant transformation.
肾混合上皮间质瘤(mesk)是一种新发现的罕见肾肿瘤亚型;已经报告了大约100例病例。我们报告一例MESTK与详细的临床病理发现,提出了急诊科肉眼血尿和血块潴留管理根治性肾切除术。虽然MESTK是良性肿瘤,但由于缺乏典型的影像学特征,需要在肾切除术后才能与其他恶性肿瘤区分。它们会引起严重的后遗症;包括肉眼血尿和严重的血红蛋白下降,正如我们在这里所展示的病例。这就是为什么早期诊断和治疗这种疾病很重要。本病例强调了在出现肉眼血尿的患者中早期引入影像学检查的重要性。如果诊断不出该病变是血尿的根本原因,则可能导致复发和恶性转化。
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引用次数: 1
THE RELATIONSHIP BETWEEN EXPERIMENTAL ALIMENTARY OBESITY AND HARD TOOTH TISSUES MINERALIZATION 实验性消化性肥胖与硬齿组织矿化的关系
Q4 Medicine Pub Date : 2017-03-01 DOI: 10.12816/0039753
M. Marushchak, I. Krynytska, L. Mazur, I. Klishch, G. Gabor, I. Antonyshyn
Objective: Obesity has become a pan-European epidemic. More knowledge about the molecular and cellular mechanisms governing adipose tissue accumulation is needed to develop more effective preventative and therapeutic approaches to obesity. We aimed to evaluate the influence of dental micro- and macroelements contents on structural changes of hard tooth tissues in rats with diet-induced obesity. Material and Method: Experimental obesity was modelled by including sodium glutamate to the feed mixture of male, non-liner, white rats of around 3 months of age, in a ratio of 0.6:100.0 and using a high-calorie diet. The atomic absorption spectrophotometer with flame and graphite furnace was used to quantify micro- and macroelement content. To evaluate structural changes of hard tooth tissues we analysed histological specimens prepared from central incisors of upper and lower jaws. Results: Overall, during the experiment period, the concentrations of minerals in hard tooth tissues decreased as follows: calcium, by 1.5 times; magnesium, by 11.8 times; zinc, by 3.6 times; and copper to practically negligible levels (p<0.05). Histological investigations showed significantly enlarged enamel areas with disrupted structure due to the destruction of enamel prisms. Dentine injury was characterized by dentine channels destruction. Their amount significantly decreased in the cement-enamel junction area and near pulpa area as well, and that results in trophic disorders and hard tooth tissues destruction. Conclusion: These data provide evidence that mineralization process of hard tooth tissues was negatively affected in rats with diet-induced obesity.
目的:肥胖已成为泛欧的流行病。需要更多关于控制脂肪组织积聚的分子和细胞机制的知识,以开发更有效的肥胖预防和治疗方法。我们旨在评估饮食诱导肥胖大鼠牙齿微量元素和常量元素含量对硬牙组织结构变化的影响。材料和方法:通过将谷氨酸钠以0.6:100.00的比例加入约3个月大的雄性、非线性、白色大鼠的饲料混合物中,并使用高热量饮食,来模拟实验性肥胖。采用火焰石墨炉原子吸收分光光度计对微量元素和常量元素含量进行了测定。为了评估硬牙组织的结构变化,我们分析了上下颌中切牙的组织学标本。结果:总的来说,在实验期间,硬齿组织中的矿物质浓度下降如下:钙,下降1.5倍;镁含量提高11.8倍;锌提高3.6倍;组织学研究显示,由于釉质棱柱的破坏,釉质区域明显增大,结构紊乱。牙本质损伤以牙本质通道破坏为特征。它们的数量在水泥-釉质结合区和牙髓附近也显著减少,这导致营养紊乱和硬牙组织破坏。结论:这些数据表明,饮食诱导的肥胖大鼠的硬齿组织矿化过程受到了负面影响。
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引用次数: 12
The Correlation between Academic and Practical Achievements of a Group of Jordanian Dental Students 一组约旦牙科学生学术成就与实践成就的相关性
Q4 Medicine Pub Date : 2017-03-01 DOI: 10.12816/0039752
A. A. Al-Asmar, A. Sabra, F. Sawair, Z. Baqain
Objectives: In a country where admission to dental schools is based on academic achievement of students, the aim of the study is to investigate the correlation between the practical achievements and the academic performance of dental students. In addition to determining if a correlation exists between dental students’ grades in the preclinical courses and their clinical performance. Methods: Academic and preclinical/clinical grades were collected for third, fourth and fifth year students who graduated from the School of Dentistry at The University of Jordan, in 2014, and 2015. Two courses (operative dentistry and fixed prosthodontics) were selected. Corre-lations comparing academic and practical grades and correlations comparing preclinical and clinical grades were done for the total samples of third, fourth, and fifth year students for each course. Results: Statistically significant weak to moderate positive correlations were found between academic and practical courses in each year and between the practical courses in preclinical and clinical years (P < 0.01). Conclusion: The correlations and its degree indicate that achievement of students in practical dental courses could be partly influenced by their grades in theoretical courses and that their achievement in clinical courses could be partly predicted by their grades in preclinical practical courses. However, other confounding factors such as genuine artistic skills of students, factors related to supervisors of clinical sessions, patients' factors, and tolerability of student to cope with stress of practical or clinical sessions are additional factors that should be considered.
目的:在一个以学生的学业成绩为入学标准的国家,本研究的目的是调查牙科学生的实际成就与学业成绩之间的相关性。除了确定牙科学生在临床预科课程中的成绩与他们的临床表现之间是否存在相关性之外。方法:收集2014年和2015年约旦大学牙科学院毕业的三年级、四年级和五年级学生的学业成绩和临床前/临床成绩。选择牙外科和固定修复两个疗程。对每门课程的三、四、五年级学生的总样本进行了学术和实践成绩的相关性比较以及临床前和临床成绩的相关性比较。结果:各学年的学术课程与实践课程、临床前学年的实践课程与临床学年的实践课程之间存在有统计学意义的弱至中度正相关(P < 0.01)。结论:相关关系及其程度表明,牙科实践课程学生的成绩可受理论课程成绩的部分影响,临床课程学生的成绩可受临床前实践课程成绩的部分预测。然而,其他混杂因素,如学生真正的艺术技能,与临床课程导师有关的因素,患者因素,以及学生应对实践或临床课程压力的耐受性,都是应该考虑的额外因素。
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引用次数: 3
期刊
Jordan Medical Journal
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