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Antimicrobial susceptibility pattern and multidrug resistance ındex in Pseudomonas aeruginosa among clinical isolates in Denizli, Turkey 土耳其Denizli临床分离株中铜绿假单胞菌的耐药性模式和多药耐药性
Q4 Medicine Pub Date : 2018-07-31 DOI: 10.4314/thrb.v20i3.6
Selma Kırac, Dilek Keskin, Muradiye Yarar
Background: Pseudomonas aeruginosa is an important hospital infection agent causing morbidity and mortality with the ability to gain resistance to many antimicrobials. The objective of this study was to determine the sensitivity profiles of nosocomial P.aeruginosa isolates in Denizli, Turkey.Methods: A total 120 P. aeruginosa strains which were isolated from specimens sent to the microbiology laboratory between January 2015 and December 2015 were investigated. Antimicrobial resistance was determined by agar disc diffusion method using Mueller-Hinton agar according to Clinical and Laboratory Standards Institute recommendations.Results: With respect to sensitivity pattern, the most sensitive antimicrobials were  Amikacin, colistin, tobramisin, netilmicin and gentamicin  and the resistance rates were detected as 97%, 96%, 92%, 90%, 83%, respectively over 120 P. aeruginosa strains. The sensitivity rates for the other antimicrobials were 56% for Piperacilin and 54% for Tazobactam. P. aeruginosa strains 62 (52%) isolates showed multiple antimicrobial resistance to 13 antimicrobialsConclusion: To prevent the spread of the resistant bacteria, it is critically important to have strict antimicrobial policies while surveillance programmes for multidrug resistant organisms and infection control procedures need to be implemented. In the meantime, it is desirable that the antimicrobial susceptibility pattern of bacterial pathogens like P. aeruginosa in specialized clinical units to be continuously monitored and the results readily made available to clinicians so as to minimize the development of resistance.
背景:铜绿假单胞菌是一种重要的医院感染源,可引起发病率和死亡率,并对多种抗菌药物产生耐药性。本研究的目的是确定土耳其德尼兹利医院分离的铜绿假单胞菌的敏感性特征。方法:对2015年1月至2015年12月期间从送往微生物实验室的标本中分离的120株铜绿假单胞杆菌进行调查。根据临床和实验室标准研究所的建议,使用Mueller-Hinton琼脂通过琼脂盘扩散法测定抗菌药物耐药性。结果:从敏感性模式来看,敏感度最高的抗菌药物为阿米卡星、粘菌素、托巴霉素、奈替米星和庆大霉素,对120株铜绿假单胞菌的耐药率分别为97%、96%、92%、90%、83%。其他抗菌药物对哌拉西林和他唑巴坦的敏感率分别为56%和54%。铜绿假单胞菌62株(52%)对13种抗菌药物表现出多重耐药性结论:为了防止耐药细菌的传播,制定严格的抗菌政策至关重要,同时需要实施多药耐药生物的监测计划和感染控制程序。同时,希望对专业临床单位中细菌病原体(如铜绿假单胞菌)的抗微生物易感性模式进行持续监测,并将结果随时提供给临床医生,以最大限度地减少耐药性的发展。
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引用次数: 0
Diagnostic utility of abdominal ultrasound in the evaluation of abdomino-pelvic lesions at Bugando Medical Centre in Mwanza, Tanzania 在坦桑尼亚姆万扎的布甘多医疗中心,腹部超声在评估腹部-盆腔病变中的诊断效用
Q4 Medicine Pub Date : 2018-07-23 DOI: 10.4314/thrb.v20i3.5
Mohamed S. Binde, Godrey Kasanga, P. Chalya, W. Mahalu
Background: Despite the fact that abdominal ultrasound has been widely used in many centres in Tanzania as a primary diagnostic imaging for patients with abdomino-pelvic lesions, its diagnostic utility has not yet been assessed in Tanzania, and therefore its use as an alternative diagnostic tool in patients with abdomino-pelvic lesions is not justified. This study aimed to determine the utility of abdominal ultrasound in the diagnosis of abdomino-pelvic lesions in our local setting.Methods: This was a cross sectional study to evaluate the diagnostic utility of abdominal ultrasound in patients presenting with abdomino-pelvic lesions at Bugando Medical Centre between January 2017 and July 2017. Abdominal ultrasonographic findings were cross-tabulated against operative findings (the gold standard). Then, the sensitivity, specificity, accuracy, Positive Predictive Value (PPV), Negative Predictive Value (NPV) and accuracy were calculated to determine the diagnostic utility of abdominal ultrasound.Results: A total of 146 patients (M: F ratio = 1: 2.2) were studied. The mean age at diagnosis was 39.3 years. The diagnostic utility of abdominal ultrasound in terms of sensitivity, specificity, PPV, NPV and accuracy were 39.4-100%, 0-100%, 64.7-100%, 0-100% and 40.8-100% respectively.  The kappa statistic (қ) showed good to excellent agreement with the operative findings, the gold standard (қ = 0.75-1.00).Conclusion: The diagnostic utility of abdominal ultrasound in detecting abdomino-pelvic lesions is much lower than that seen in developed countries, hence, abdominal ultrasound is not a reliable tool in detecting abdomino-pelvic lesions at Bugando Medical Centre and therefore its use should be supplemented with abdominal CT scan in selected cases.
背景:尽管腹部超声已在坦桑尼亚的许多中心被广泛用作腹盆腔病变患者的主要诊断成像,但其诊断效用尚未在坦桑尼亚得到评估,因此将其用作腹盆腔损伤患者的替代诊断工具是不合理的。本研究旨在确定腹部超声在我们的局部环境中诊断腹盆腔病变的实用性。方法:这是一项横断面研究,旨在评估腹部超声在布甘多医疗中心2017年1月至2017年7月期间对腹盆腔病变患者的诊断效用。腹部超声检查结果与手术结果对照(金标准)。然后,计算腹部超声的敏感性、特异性、准确性、阳性预测值(PPV)、阴性预测值(NPV)和准确性,以确定腹部超声的诊断效用。结果:共对146例患者进行了研究(男:女比例=1:2.2)。诊断时的平均年龄为39.3岁。腹部超声诊断的敏感性、特异性、PPV、NPV和准确性分别为39.4-100%、0-100%、64.7-100%、0-100%和40.8-100%。kappa统计量(=0.75-1.00)与手术结果、金标准(=0.75-100)显示出良好的一致性。结论:腹部超声在检测腹盆腔病变中的诊断实用性远低于发达国家,因此,在布甘多医疗中心,腹部超声不是检测腹盆腔病变的可靠工具,因此在选定的病例中,应辅以腹部CT扫描。
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引用次数: 1
Seroprevalence of hepatitis E among restaurant food handlers in Ibadan, Nigeria 尼日利亚伊巴丹市餐馆食品处理人员戊型肝炎血清流行率
Q4 Medicine Pub Date : 2018-07-23 DOI: 10.4314/thrb.v20i3.2
A. Fowotade, Akande Oluseyi, A. Gbaja, V. O. Ogunleye, A. Ajayi, A. Kehinde
 Background: Hepatitis E virus (HEV) is one of the causative agent of acute viral hepatitis in humans. HEV is an important public health disease in many parts of the world because it is transmitted faeco-orally.  Majority of the documented studies on hepatitis E virus in Nigeria have focused on pregnant women and animal handlers with limited data among food handlers. Thus the current study aimed at investigating the prevalence of HEV infection among food handlers operating within the premises of a tertiary care facility.Methods: One hundred and seventy seven (177) food handlers were screened using commercial Enzyme-Linked Immuno-Sorbent Assay (ELISA) to detect IgM antibodies to Hepatitis E. A semi-structured questionnaire was used to assess risk factors for HEV infection.Results: HEV IgM antibodies were detected in 16 (9.0%) of the participants. Age-specific HEV IgM seroprevalence appeared to decrease with age, however there were no significant differences in HEV IgM seropositivity regarding age (P=0.251), gender (P = 0.231), marital status (P=0.735) and religion (P = 0.906). Significant risk factors for HEV IgM seropositivity included source of water for drinking (P=0.03) and the use of soap for hand washing (P=0.02).Conclusion: Our findings suggest that HEV remains a public health problem, as the virus circulates at low but considerable levels especially among food handlers; thus posing a threat to potential contacts. Proper hand washing practices as well as provision of portable water are important factors for the control of Hepatitis E.
背景:戊型肝炎病毒(HEV)是人类急性病毒性肝炎的病原之一。戊型肝炎在世界许多地区是一种重要的公共卫生疾病,因为它是经粪口传播的。尼日利亚关于戊型肝炎病毒的大多数文献研究集中在孕妇和动物处理者身上,食品处理者的数据有限。因此,目前的研究旨在调查在三级保健机构内操作的食品处理人员中戊肝病毒感染的流行情况。方法:采用商用酶联免疫吸附试验(ELISA)对177名食品加工人员进行筛查,检测戊型肝炎IgM抗体。采用半结构化问卷法评估HEV感染的危险因素。结果:16人(9.0%)检测出HEV IgM抗体。年龄特异性HEV IgM血清阳性率随着年龄的增长而下降,但HEV IgM血清阳性率在年龄(P=0.251)、性别(P= 0.231)、婚姻状况(P=0.735)和宗教(P= 0.906)之间无显著差异。HEV IgM血清阳性的显著危险因素包括饮用水源(P=0.03)和使用肥皂洗手(P=0.02)。结论:我们的研究结果表明,HEV仍然是一个公共卫生问题,因为该病毒的传播水平虽低,但相当可观,特别是在食品处理人员中;因此对潜在接触者构成威胁。正确的洗手方法和提供饮用水是控制戊型肝炎的重要因素。
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引用次数: 5
Demographic data of patients with β-thalassemia major recorded in the electronic system in the north of Iran, 2016 2016年伊朗北部电子系统中记录的主要β地中海贫血患者的人口统计数据
Q4 Medicine Pub Date : 2018-07-12 DOI: 10.4314/thrb.v20i3.3
M. Kosaryan, H. Karami, Hadi Darvishi-Khezri, Rozita Akbarzadeh, Aily Aliasgharian, Khadijeh Bromand
Background: Major thalassemia prevention project in Iran began in 1997. Mazandaran Province in northern Iran took effective steps in preventing the birth of patients with thalassemia major in the country. We report on the demographic status of patients with thalassemia major registered in the electronic system of Mazandaran Province in Iran.Methods: The web-based application of the Mazandaran Thalassemia Registry (THRegistry) was designed based on the Net Framework platform in VB.Net and the 2014Sql Server database. The information source included clinical records in 14 thalassemic wards of the Mazandaran province hospitals. Epidemiological data of patients and date of transfusion, blood group, educational status, employment, marital status and having children were recorded.Results: The study population was 1,725 patients including 889 (51.5%) women and 836 (48.5%) men with a mean age of 30±9.6 years. A total of 188 patients born have been identified after the launch of the country's disease prevention plan in 1997. Prenatal diagnosis (PND) services were not used in 99 cases, PND result was mistaken in 6 other cases and in the remaining 5 cases PND was performed. A total of 1,314 patients (76.2%) were blood transfusion dependent thalassemia (TDT). Mean haemoglobin level in male and female patients was 9.4±6.3 and 9.01±5.1/100 g/dl, respectively. The mean age of onset of transfusion was 4±6.3 years. A total of 382 cases (22.1%) of married patients had a child of their own.Conclusions: The system is a good resource to design descriptive and cohort studies, survival studies, therapeutic planning, and observation of the success of the major thalassemia prevention project.
背景:1997年,伊朗开始实施重大地中海贫血预防项目。伊朗北部的马赞达兰省采取了有效步骤,在该国预防重度地中海贫血患者的出生。我们报告了在伊朗马赞达兰省电子系统中登记的地中海贫血患者的人口统计状况。方法:基于。Net Framework平台,在VB中设计基于web的Mazandaran Thalassemia Registry (THRegistry)应用程序。Net和2014Sql Server数据库。资料来源包括马赞达兰省医院14个地中海贫血病房的临床记录。记录患者流行病学资料及输血日期、血型、学历、就业、婚姻状况、有无子女等。结果:研究人群为1725例患者,其中女性889例(51.5%),男性836例(48.5%),平均年龄30±9.6岁。自1997年启动国家疾病预防计划以来,共确定了188名出生的患者。未进行产前诊断(PND)者99例,错误诊断者6例,行产前诊断者5例。输血依赖型地中海贫血(TDT) 1,314例(76.2%)。男性和女性患者的平均血红蛋白水平分别为9.4±6.3和9.01±5.1/100 g/dl。输血的平均发病年龄为4±6.3岁。已婚患者中有子女的382例(22.1%)。结论:该系统是设计描述性和队列研究、生存研究、治疗计划和观察重大地中海贫血预防项目成功的良好资源。
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引用次数: 2
Utilisation of voluntary counselling and testing services among bar waitresses in Kinondoni District, Dar es Salaam, Tanzania 坦桑尼亚达累斯萨拉姆Kinondoni区酒吧服务员利用自愿咨询和检测服务
Q4 Medicine Pub Date : 2018-07-01 DOI: 10.4314/thrb.v20i3.1
A. Tengia–Kessy, Dominica E. Lyamuya
 Background: Tanzania is among sub-Saharan countries severely affected by the HIV and AIDS epidemic, with an increased burden among high-risk populations, such as bar waitresses. Voluntary counselling and testing (VCT) is among effective approaches to slow down the spread of HIV infection and minimize its impact. However, little information is available on the extent of utilisation of VCT services among bar waitresses. The study examined utilisation of VCT services and its influencing factors among bar waitresses in Kinondoni district, Dar es Salaam, Tanzania.Methods: We used an interview schedule to gather information on VCT utilisation from 378 bar waitresses, identified using a multi-stage sampling technique. Data were analysed using the Statistical Package for Social Science (Version 15.0). A p-value less than 0.05 was used as a cut-off value for availability of a statistical association between VCT utilisation and related independent factors. Logistic regression models were employed to assess independent correlates of VCT use.Results: The mean (standard deviation) age of the respondents was 26.1 (5.0) years. About 60% had never been married and about 70% had at least one child at the time of the survey. Majority of the bar waitresses (89.7%) affirmed to have ever utilized VCT services at some point in their lifetime. Despite the high level of knowledge on VCT (71.4%), the services were irregularly utilized with less than half (45.5%) of the respondents utilizing them within six months prior to the survey. Independent predictors for service utilisation included having a child, having higher knowledge on VCT, using a condom in the most recent sexual act as well as lack of fear of positive HIV results or stigmatization.Conclusions: Utilisation of VCT services is high among bar waitresses in Kinondoni district. However, the services are not utilised regularly as recommended for high-risk populations. Findings call for comprehensive strategies to enhance effective service utilisation and further studies based on a broader and more inclusive sample size. 
背景:坦桑尼亚是受艾滋病毒和艾滋病严重影响的撒哈拉以南国家之一,酒吧女招待等高危人群的负担日益加重。自愿咨询和检测(VCT)是减缓艾滋病毒感染传播和尽量减少其影响的有效方法之一。然而,关于酒吧女招待使用VCT服务的程度的信息很少。该研究调查了坦桑尼亚达累斯萨拉姆Kinondoni区酒吧女招待中VCT服务的使用情况及其影响因素。方法:我们使用访谈时间表收集378名酒吧女招待的VCT使用信息,使用多阶段抽样技术确定。使用社会科学统计软件包(15.0版)分析数据。使用小于0.05的p值作为VCT使用与相关独立因素之间存在统计学关联的截断值。采用Logistic回归模型评估VCT使用的独立相关因素。结果:被调查者的平均(标准差)年龄为26.1(5.0)岁。约60%的人在调查时从未结过婚,约70%的人至少有一个孩子。大多数酒吧女招待(89.7%)肯定曾在其一生中的某个时候使用过VCT服务。尽管受访者对VCT有很高的认识(71.4%),但他们并不经常使用这些服务,只有不到一半(45.5%)的受访者在调查前六个月内使用过这些服务。服务利用的独立预测因素包括有孩子,对VCT有更高的了解,在最近的性行为中使用避孕套,以及不害怕艾滋病毒阳性结果或污名化。结论:基隆多尼区酒吧女招待对VCT服务的使用率较高。然而,高危人群并没有按照建议定期使用这些服务。调查结果要求制定全面战略,以提高服务的有效利用,并在更广泛和更具包容性的样本量基础上进行进一步研究。
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引用次数: 0
Seroprevalence of hepatitis E among restaurant food handlers in Ibadan, Nigeria 尼日利亚伊巴丹餐馆食品从业人员中戊型肝炎的血清流行率
Q4 Medicine Pub Date : 2018-07-01 DOI: 10.4314/THRB.V20I3
M. Kosaryan, H. Karami, Hadi Darvishi-Khezri, Rozita Akbarzadeh, Aily Aliasgharian, Khadijeh Bromand
Background: Hepatitis E virus (HEV) is one of the causative agent of acute viral hepatitis in humans. HEV is an important public health disease in many parts of the world because it is transmitted faeco-orally.  Majority of the documented studies on hepatitis E virus in Nigeria have focused on pregnant women and animal handlers with limited data among food handlers. Thus the current study aimed at investigating the prevalence of HEV infection among food handlers operating within the premises of a tertiary care facility. Methods: One hundred and seventy seven (177) food handlers were screened using commercial Enzyme-Linked Immuno-Sorbent Assay (ELISA) to detect IgM antibodies to Hepatitis E. A semi-structured questionnaire was used to assess risk factors for HEV infection. Results : HEV IgM antibodies were detected in 16 (9.0%) of the participants. Age-specific HEV IgM seroprevalence appeared to decrease with age, however there were no significant differences in HEV IgM seropositivity regarding age (P=0.251), gender (P = 0.231), marital status (P=0.735) and religion (P = 0.906). Significant risk factors for HEV IgM seropositivity included source of water for drinking (P=0.03) and the use of soap for hand washing (P=0.02). Conclusion : Our findings suggest that HEV remains a public health problem, as the virus circulates at low but considerable levels especially among food handlers; thus posing a threat to potential contacts. Proper hand washing practices as well as provision of portable water are important factors for the control of Hepatitis E.
背景:戊型肝炎病毒是人类急性病毒性肝炎的病原体之一。HEV是世界许多地区的一种重要公共卫生疾病,因为它是通过粪便经口传播的。尼日利亚大多数关于戊型肝炎病毒的文献研究都集中在孕妇和动物饲养者身上,食品饲养者的数据有限。因此,目前的研究旨在调查在三级护理机构内操作的食品处理人员中HEV感染的流行率。方法:采用商业酶联免疫吸附试验(ELISA)对177名食品加工人员进行筛查,检测戊型肝炎IgM抗体。采用半结构调查表评估戊型肝炎感染的危险因素。结果:16例(9.0%)受试者检测到HEV IgM抗体。年龄特异性HEV IgM血清阳性率似乎随着年龄的增长而下降,但HEV IgM阳性率在年龄(P=0.251)、性别(P=0.231)、,婚姻状况(P=0.735)和宗教信仰(P=0.906)。HEV IgM血清阳性的重要风险因素包括饮用水源(P=0.03)和洗手用肥皂(P=0.02)。结论:我们的研究结果表明,HEV仍然是一个公共卫生问题,因为病毒的传播水平很低,但相当高,尤其是在食品处理者中;从而对潜在的接触构成威胁。正确的洗手习惯以及提供饮用水是控制戊型肝炎的重要因素。
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引用次数: 8
Breastfeeding information seeking behaviour among parents in Mbeya City, Tanzania 坦桑尼亚姆贝亚市父母寻求母乳喂养信息的行为
Q4 Medicine Pub Date : 2018-06-26 DOI: 10.4314/thrb.v20i3.8
Neema Mwaisela, Kelefa Mwantimwa
Background: Majority of mothers in Tanzania fail to practice effective breastfeeding for various reasons. The objective of this study was to determine breastfeeding- related information seeking behaviour among parents in Mbeya City of Tanzania.Methods: A descriptive cross-sectional survey design was used. Parents of infants and children aged between 0-2 years and health care workers were interviewed. Secondary data was collected by using documentary review. Information sought was related to the perceptions of parents towards the usefulness of breastfeeding and breastfeeding practices. The observation method was used to identify and verify the actual available, accessible, and usable breastfeeding information.Results: The key findings suggest that information needs of parents and sources and channels used vary and depended on the time intended to breastfed the child. Mainly, the parents’ needs information on nutritious food, introduction of complimentary food, breast care, and care techniques for when away from babies, frequency and implications of breastfeeding. Friends, relatives, neighbours, health professional were the most commonly sources of breastfeeding information. The majority of parents perceived that access to and usage of breastfeeding information improve breastfeeding rate, decision making, increase awareness and knowledge, and breastfeeding practices.Conclusion: Information seeking behaviour varies from one parent to another hence the varying preferences in informal and formal sources. Increasing accessibility and usability of breastfeeding information is necessary in ensuring that one of the basic human rights is safeguarded
背景:坦桑尼亚的大多数母亲由于各种原因未能实行有效的母乳喂养。本研究的目的是确定坦桑尼亚姆贝亚市父母与母乳喂养相关的信息寻求行为。方法:采用描述性横断面调查设计。采访了0-2岁婴幼儿的父母和医护人员。二次数据是通过文献综述收集的。所寻求的信息与父母对母乳喂养和母乳喂养做法有用性的看法有关。观察方法用于识别和验证实际可用、可访问和可用的母乳喂养信息。结果:关键发现表明,父母的信息需求、使用的来源和渠道各不相同,并取决于母乳喂养孩子的时间。主要是父母对营养食品的需求信息、免费食品的介绍、乳房护理、远离婴儿时的护理技术、母乳喂养的频率和影响。朋友、亲戚、邻居、卫生专业人员是母乳喂养信息的最常见来源。大多数父母认为,获得和使用母乳喂养信息可以提高母乳喂养率、决策、提高认识和知识以及母乳喂养做法。结论:寻求信息的行为因父母而异,因此在非正式和正式来源中的偏好也各不相同。提高母乳喂养信息的可及性和可用性对于确保一项基本人权得到保障是必要的
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引用次数: 5
Bilateral congenital choanal atresia in a 16-year old girl at Muhimbili National Hospital, Tanzania 坦桑尼亚Muhimbili国家医院一名16岁女孩双侧先天性后鼻孔闭锁
Q4 Medicine Pub Date : 2018-06-25 DOI: 10.4314/thrb.v20i3.9
Zephania Saitabau, Martin Elimath, N. Moshi, E. Richard, D. Ntunaguzi
Background: Bilateral choanal atresia refers to a congenital anomaly whereby a child is born with bilateral imperforate posterior nares. In most cases the diagnosis is established soon after birth. Establishment of the diagnosis requires a high index of suspicion by clinicians. The objective was thus to report an unusual case which went undiagnosed for many years and review the few available literatures.Case presentation: A 16-year old girl presented to the otorhinolaryngology clinic of Muhimbili National Hospital in Tanzania with a long standing history of bilateral nasal obstruction. The condition was reported to be present since birth and this was accompanied by mouth breathing and persistent bilateral nasal discharge. The patient also reported a history suggestive of respiratory distress after birth which necessitated oxygen therapy and difficulty in breastfeeding where she was kept on expressed breast milk during the first few weeks of life. Nasal endoscopy was done clinic and the diagnosis of bilateral congenital choanal atresia was made. Computerized tomography scan of the nose and paranasal sinuses revealed bilateral choanal atresia of mixed type. Surgical perforation of the atretic choanae without stenting was done endoscopically under general anaesthesia.Conclusion: Bilateral congenital choanal atresia is an otorhinolaryngological emergency and should be established promptly both in resource limited settings and in areas where advanced tools are in situ to prevent its morbidity and mortality if it goes unestablished.
背景:双侧后鼻孔闭锁是指先天性畸形,出生时患有双侧后鼻孔无孔。在大多数情况下,诊断是在出生后不久确定的。诊断的确定需要临床医生的高度怀疑指数。因此,目的是报告一例多年未确诊的异常病例,并回顾为数不多的可用文献。病例介绍:一名16岁女孩在坦桑尼亚Muhimbili国立医院耳鼻喉科诊所就诊,有长期双侧鼻阻塞病史。据报道,这种情况自出生以来就存在,并伴有口呼吸和持续的双侧鼻腔分泌物。该患者还报告了出生后呼吸窘迫的病史,这需要氧气治疗,并且在出生的头几周,她一直使用母乳喂养。临床应用鼻内镜对双侧先天性后鼻孔闭锁进行诊断。鼻腔和鼻窦的计算机断层扫描显示双侧后鼻孔闭锁为混合型。闭锁性choanae的手术穿孔在全身麻醉下进行,无需支架植入。结论:双侧先天性后鼻孔闭锁是一种耳鼻喉科急诊,无论是在资源有限的环境中还是在有先进工具的地区,都应及时建立,以防止其发病率和死亡率。
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引用次数: 0
High rate of drinking water contamination due to poor storage in squatter settlements in Mwanza, Tanzania 在坦桑尼亚姆万扎,由于棚户区储存不良,饮用水污染率很高
Q4 Medicine Pub Date : 2018-06-21 DOI: 10.4314/thrb.v20i3.7
M. Mushi, Oswald E. Mpelasoka, H. Mazigo, L. McLeod, N. Moremi, M. Mirambo, S. Mshana
Background: Drinking water of acceptable quality is supposed to be free from faecal coliform and chemical substances that may be hazardous to human health. Water treatment and safe storage at the household level has been advocated as effective means of ensuring safe drinking water. This study was undertaken to determine the microbiological quality of the drinking water at household level in the squatter settlements in the city of Mwanza, Tanzania.Methods: A cross-sectional study was conducted between June 2014 and September 2014.  A total of 15 randomly selected water sources (tap) and 207 households’ drinking water samples from these sources were studied to ascertain level of water contamination using Membrane Filtration Method. Pre-tested questionnaire was used to collect demographic and other data regarding water treatment and storage.  Data were entered, cleaned and analysed using STATA Version 11.Results:  All 15 samples from tap used as water sources were found to be free of indicator organism (Escherichia coli) while 109 (52.66%) of drinking water samples from 207 households were found to be contaminated with E. coli.  All contaminated drinking water samples were from containers with no cover and spigot. Conclusions: There is a significant level of deterioration of water quality from the source to the drinking cup. Efforts to ensure quality storage methods for drinking water should be addressed at household level.
背景:质量合格的饮用水应该不含粪便大肠菌群和可能危害人类健康的化学物质。提倡在家庭一级进行水处理和安全储存,以此作为确保安全饮用水的有效手段。本研究旨在确定坦桑尼亚姆万扎市棚户区家庭饮用水的微生物质量。方法:2014年6月至2014年9月进行了一项横断面研究。共对15个随机选择的水源(水龙头)和207户家庭的饮用水样本进行了研究,以使用膜过滤法确定水污染水平。预测试问卷用于收集有关水处理和储存的人口统计和其他数据。使用STATA第11版输入、清洁和分析数据。结果:所有15个用作水源的水龙头样本均不含指示生物(大肠杆菌),而207户家庭的109个饮用水样本(52.66%)被发现受大肠杆菌污染。所有受污染的饮用水样本都来自没有盖子和龙头的容器。结论:从水源到饮用杯的水质都有显著的恶化。应在家庭一级努力确保饮用水的优质储存方法。
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引用次数: 5
Malnutrition and associated factors among adults starting on antiretroviral therapy at PASADA Hospital in Temeke District Tanzania. 坦桑尼亚Temeke区PASADA医院开始接受抗逆转录病毒治疗的成年人营养不良及相关因素。
Q4 Medicine Pub Date : 2018-04-01 DOI: 10.4314/THRB.V20I2.5
T. Kabalimu, E. Sungwa, Warles C. Lwabukuna
Background: Malnutrition is known to play a significant role in HIV/AIDS progression. Severe malnutrition has been previously found to be associated with early mortality among people living with HIV/AIDS (PLHIV) undergoing anti-retroviral therapy (ART) in Sub-Saharan Africa. The objective of this study was to determine the prevalence and factors associated with malnutrition among adult PLHIV attending care and treatment centre (CTC) in Temeke District, Tanzania. Methods: The cross-sectional descriptive study involved consecutive eligible patients attending the CTC for initiating in ART, between January and April, 2014. All participants who agreed to sign a consent form were enrolled. The participants had undergone baseline workup for ART initiation (by CTC), which included blood tests for liver and renal function tests, and CD4+ cell count, using calibrated instruments and standard techniques. In all patients the weight and height were measured to calculate the body mass index (BMI), denoting the nutritional status. This parameter was recorded in the study instrument together with the CD4+ count for each patient. A structured questionnaire was used to obtain more information, namely demographic and lifestyle data. Results:  A total of 125 patients were included in this study . The prevalence of malnutrition among participants was 19.4%.  Those with severe malnutrition comprised of 9%. Significant association was noted between malnutrition and irregular income (OR= 3.8, CI: 1.2-11.5) and also inability to get at least two meals a day (OR= 3.4, CI: 1.2-9.2).  Severe malnutrition was significantly associated with the CD4+ counts of <200 cells/mm (OR =7.6; CI: 1.7-34.6). Conclusion : About 19% of participants were malnourished at the time of initiation of ART and among them 9% were severely malnourished. The most important risks for malnutrition were found to be irregular income and inability to get adequate feeding. This calls for routine nutritional assessment at CTCs prior to initiation of ART so as to identify those who need immediate intervention, including those with severe malnutrition.
背景:众所周知,营养不良在艾滋病毒/艾滋病的发展中起着重要作用。在撒哈拉以南非洲接受抗逆转录病毒治疗的艾滋病毒/艾滋病患者中,严重营养不良与早期死亡率有关。本研究的目的是确定坦桑尼亚Temeke区成人PLHIV护理和治疗中心(CTC)中营养不良的患病率和相关因素。方法:横断面描述性研究涉及2014年1月至4月期间参加CTC启动ART的连续合格患者。所有同意签署同意书的参与者都被纳入了研究。参与者接受了ART启动的基线检查(通过CTC),其中包括肝和肾功能测试的血液测试,以及使用校准仪器和标准技术的CD4+细胞计数。在所有患者中,测量体重和身高以计算身体质量指数(BMI),表示营养状况。该参数与每个患者的CD4+计数一起记录在研究仪器中。使用结构化问卷来获得更多信息,即人口统计和生活方式数据。结果:本研究共纳入125例患者。参与者中营养不良的患病率为19.4%,严重营养不良者占9%。营养不良与收入不规律(OR=3.8,CI:1.2-11.5)和一天至少不能吃两顿饭(OR=3.4,CI:1.2-9.2)之间存在显著相关性。严重营养不良与CD4+计数<200细胞/mm显著相关(OR=7.6;CI:1.7-34.6)。结论:约19%的参与者在开始ART时营养不良,其中9%严重营养不良。营养不良最重要的风险是收入不规律和无法获得足够的食物。这就要求在开始抗逆转录病毒疗法之前对CTC进行常规营养评估,以确定那些需要立即干预的人,包括那些严重营养不良的人。
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引用次数: 21
期刊
Tanzania Journal of Health Research
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