Hip fractures in the elderly pose a significant clinical challenge, with high short-term mortality rates. The Nottingham Hip Fracture Score (NHFS) has proven useful in predicting 30-day mortality in European and Asian populations, but its validity in the Mexican population has not been widely assessed.
General objective
To validate the NHFS in predicting 30-day mortality following hip fracture in a Mexican population.
Methodology
An observational, longitudinal, and prospective study was conducted with 143 patients over 60 years of age with hip fractures treated surgically at Hospital General de Zona No. 16 of IMSS. NHFS was applied upon admission, and health status was verified 30 days post-surgery. The area under the ROC curve (AUC), sensitivity, specificity, and model calibration were calculated.
Results
The 30-day mortality rate was 14.7%. The NHFS had an AUC of 0.72, indicating moderate predictive capacity. A cutoff score of 3.5 yielded 85.7% sensitivity and 24% specificity. A higher cutoff of 4.5 improved specificity (45%) but reduced sensitivity (81%).
Conclusions
The NHFS is a useful tool for predicting 30-day mortality in the Mexican population with hip fractures, though its discriminative ability is moderate. A 3.5 cutoff is recommended when prioritizing sensitivity in clinical settings.
{"title":"Validation of the Nottingham Hip Fracture Score (NHFS) to predict 30-day mortality following hip fracture in a Mexican population","authors":"Mayra Arely Serrano-Lugo , Iván Luján-Hernández , Ma. Elena Ledesma-González , Quitzia Libertad Torres-Salazar","doi":"10.1016/j.regg.2024.101610","DOIUrl":"10.1016/j.regg.2024.101610","url":null,"abstract":"<div><h3>Introduction</h3><div>Hip fractures in the elderly pose a significant clinical challenge, with high short-term mortality rates. The <em>Nottingham Hip Fracture Score</em> (NHFS) has proven useful in predicting 30-day mortality in European and Asian populations, but its validity in the Mexican population has not been widely assessed.</div></div><div><h3>General objective</h3><div>To validate the NHFS in predicting 30-day mortality following hip fracture in a Mexican population.</div></div><div><h3>Methodology</h3><div>An observational, longitudinal, and prospective study was conducted with 143 patients over 60 years of age with hip fractures treated surgically at Hospital General de Zona No. 16 of IMSS. NHFS was applied upon admission, and health status was verified 30 days post-surgery. The area under the ROC curve (AUC), sensitivity, specificity, and model calibration were calculated.</div></div><div><h3>Results</h3><div>The 30-day mortality rate was 14.7%. The NHFS had an AUC of 0.72, indicating moderate predictive capacity. A cutoff score of 3.5 yielded 85.7% sensitivity and 24% specificity. A higher cutoff of 4.5 improved specificity (45%) but reduced sensitivity (81%).</div></div><div><h3>Conclusions</h3><div>The NHFS is a useful tool for predicting 30-day mortality in the Mexican population with hip fractures, though its discriminative ability is moderate. A 3.5 cutoff is recommended when prioritizing sensitivity in clinical settings.</div></div>","PeriodicalId":39958,"journal":{"name":"Revista Espanola de Geriatria y Gerontologia","volume":"60 3","pages":"Article 101610"},"PeriodicalIF":0.0,"publicationDate":"2024-12-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142899088","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-12-24DOI: 10.1016/j.regg.2024.101609
María Villajos-Guijarro , Raquel Ramírez-Martín , Coro Mauleón-Ladrero , Victoria Déniz González , Alexander Forero Torres , Francisca Garcia-Moreno Nisa , Juan Ignacio González-Montalvo
Purpose
Analyse the influence of the nutritional status of older patients undergoing emergency abdominal surgery on postoperative complications, mortality and mean length of hospital stay.
Methods
We performed a longitudinal observational study including patients older than 80 years who underwent emergency surgery by the general surgery service for abdominal pathology, who were followed by the geriatrics service between September 2018 and May 2021. Malnutrition was diagnosed using Global Leadership Initiative on Malnutrition (GLIM) criteria, classifying patients as malnourished and normonourished. A comprehensive geriatric assessment was performed on patients, and postoperative complications, mean length of hospital stay and mortality in-hospital were recorded.
Results
131 patients were included, 84 of them were malnourished and 47 normonourished. Mean age was 86 ± 4.7 years. Malnourished patients had higher incidence of new-onset atrial fibrillation (odds ratio [OR]: 6.1, 95% confidence interval [CI]: 1.33–27.6, p < 0.05), urinary tract infection (OR 4.72, 95% CI: 1.02–21.95, p < 0.05) and bacteraemia (OR 3.51, 95% CI: 1.14–11.1, p < 0.05), compared with normonourished patients. Surgical complications were more frequent in malnourished patients (OR 3.34, 95% CI: 1.5–7.44, p < 0.05). Mean length of hospital stay in malnourished patients was longer (22.6 (±14.1)) compared with normonourished patients (15.3 (±11.9)) (p < 0.005).
Conclusion
Malnutrition in older patients (mean age 86 years old) undergoing emergency abdominal surgery is associated with a poorer clinical course; thus, it must be considered in the evaluation and follow-up of these patients.
{"title":"Impact of malnutrition on the clinical evolution in a cohort of older patients undergoing emergency surgery for abdominal pathology","authors":"María Villajos-Guijarro , Raquel Ramírez-Martín , Coro Mauleón-Ladrero , Victoria Déniz González , Alexander Forero Torres , Francisca Garcia-Moreno Nisa , Juan Ignacio González-Montalvo","doi":"10.1016/j.regg.2024.101609","DOIUrl":"10.1016/j.regg.2024.101609","url":null,"abstract":"<div><h3>Purpose</h3><div>Analyse the influence of the nutritional status of older patients undergoing emergency abdominal surgery on postoperative complications, mortality and mean length of hospital stay.</div></div><div><h3>Methods</h3><div>We performed a longitudinal observational study including patients older than 80 years who underwent emergency surgery by the general surgery service for abdominal pathology, who were followed by the geriatrics service between September 2018 and May 2021. Malnutrition was diagnosed using Global Leadership Initiative on Malnutrition (GLIM) criteria, classifying patients as malnourished and normonourished. A comprehensive geriatric assessment was performed on patients, and postoperative complications, mean length of hospital stay and mortality in-hospital were recorded.</div></div><div><h3>Results</h3><div>131 patients were included, 84 of them were malnourished and 47 normonourished. Mean age was 86<!--> <!-->±<!--> <!-->4.7 years. Malnourished patients had higher incidence of new-onset atrial fibrillation (odds ratio [OR]: 6.1, 95% confidence interval [CI]: 1.33–27.6, <em>p</em> <!--><<!--> <!-->0.05), urinary tract infection (OR 4.72, 95% CI: 1.02–21.95, <em>p</em> <!--><<!--> <!-->0.05) and bacteraemia (OR 3.51, 95% CI: 1.14–11.1, <em>p</em> <!--><<!--> <!-->0.05), compared with normonourished patients. Surgical complications were more frequent in malnourished patients (OR 3.34, 95% CI: 1.5–7.44, <em>p</em> <!--><<!--> <!-->0.05). Mean length of hospital stay in malnourished patients was longer (22.6 (±14.1)) compared with normonourished patients (15.3 (±11.9)) (<em>p</em> <!--><<!--> <!-->0.005).</div></div><div><h3>Conclusion</h3><div>Malnutrition in older patients (mean age 86 years old) undergoing emergency abdominal surgery is associated with a poorer clinical course; thus, it must be considered in the evaluation and follow-up of these patients.</div></div>","PeriodicalId":39958,"journal":{"name":"Revista Espanola de Geriatria y Gerontologia","volume":"60 2","pages":"Article 101609"},"PeriodicalIF":0.0,"publicationDate":"2024-12-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142898955","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-12-24DOI: 10.1016/j.regg.2024.101613
Nieves Fernández Letamendi , Miguel Sanz Sainz , Alberto Aso Vizán , Javier Domingo Cebollada
{"title":"Beneficio del manejo en la Unidad de Ortogeriatría en una paciente centenaria con fractura pertrocantérea bilateral simultánea de fémur proximal. A propósito de un caso","authors":"Nieves Fernández Letamendi , Miguel Sanz Sainz , Alberto Aso Vizán , Javier Domingo Cebollada","doi":"10.1016/j.regg.2024.101613","DOIUrl":"10.1016/j.regg.2024.101613","url":null,"abstract":"","PeriodicalId":39958,"journal":{"name":"Revista Espanola de Geriatria y Gerontologia","volume":"60 3","pages":"Article 101613"},"PeriodicalIF":0.0,"publicationDate":"2024-12-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142898963","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-12-23DOI: 10.1016/j.regg.2024.101607
Valentina Velasco-Muñoz , Mateo Uribe-Gaviria , Santiago Andrés Suárez-Gómez , Antonio Villamizar-Romero , Andrés Ricaurte-Fajardo , Isabel Cristina Vásquez-Vélez , Carlos A. Cano-Gutiérrez
The jellyfish Turritopsis dohrnii (T. Nutricala) is a cnidarian of the Oceaniidae family that lives in the Mediterranean Sea. It is known as the immortal jellyfish since, through a process of cell development called transdifferentiation, it manages to return to a polyp state. The role of regeneration processes and their impact on aging have been studied in recent years for their potential applications in the development of more efficient pharmacology to address disorders related to aging. Reviewing the terms related to transdifferentiation in jellyfish and understanding the underlying mechanisms can help comprehend diverse processes such as aging, regeneration, and the molecular bases of diseases like cancer. This paper's purpose is to provide a description of the regenerative characteristics of the jellyfish T. dohrnii, investigate how its regenerative processes allow it to rejuvenate, and determine if these tissue restoration processes are also found in humans.
{"title":"Regenerative characteristics of the immortal jellyfish, Turritopsis dohrnii, and their potential implications for human aging","authors":"Valentina Velasco-Muñoz , Mateo Uribe-Gaviria , Santiago Andrés Suárez-Gómez , Antonio Villamizar-Romero , Andrés Ricaurte-Fajardo , Isabel Cristina Vásquez-Vélez , Carlos A. Cano-Gutiérrez","doi":"10.1016/j.regg.2024.101607","DOIUrl":"10.1016/j.regg.2024.101607","url":null,"abstract":"<div><div>The jellyfish <em>Turritopsis dohrnii</em> (<em>T. Nutricala</em>) is a cnidarian of the Oceaniidae family that lives in the Mediterranean Sea. It is known as the immortal jellyfish since, through a process of cell development called transdifferentiation, it manages to return to a polyp state. The role of regeneration processes and their impact on aging have been studied in recent years for their potential applications in the development of more efficient pharmacology to address disorders related to aging. Reviewing the terms related to transdifferentiation in jellyfish and understanding the underlying mechanisms can help comprehend diverse processes such as aging, regeneration, and the molecular bases of diseases like cancer. This paper's purpose is to provide a description of the regenerative characteristics of the jellyfish <em>T. dohrnii</em>, investigate how its regenerative processes allow it to rejuvenate, and determine if these tissue restoration processes are also found in humans.</div></div>","PeriodicalId":39958,"journal":{"name":"Revista Espanola de Geriatria y Gerontologia","volume":"60 3","pages":"Article 101607"},"PeriodicalIF":0.0,"publicationDate":"2024-12-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142886222","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-12-23DOI: 10.1016/j.regg.2024.101615
Sergio García-González, Sara Pilar Martínez-Cisneros, José González-Fernández, Victoria Lezcano-Biosca
{"title":"Manicura gualda, lo que esconden las uñas","authors":"Sergio García-González, Sara Pilar Martínez-Cisneros, José González-Fernández, Victoria Lezcano-Biosca","doi":"10.1016/j.regg.2024.101615","DOIUrl":"10.1016/j.regg.2024.101615","url":null,"abstract":"","PeriodicalId":39958,"journal":{"name":"Revista Espanola de Geriatria y Gerontologia","volume":"60 3","pages":"Article 101615"},"PeriodicalIF":0.0,"publicationDate":"2024-12-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142886219","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-12-17DOI: 10.1016/j.regg.2024.101585
Dafne Lastra Landa , Oscar Flores-Flores , José F. Parodi
{"title":"El envejecimiento en poblaciones indígenas de la Amazonía peruana: una agenda pendiente de investigación","authors":"Dafne Lastra Landa , Oscar Flores-Flores , José F. Parodi","doi":"10.1016/j.regg.2024.101585","DOIUrl":"10.1016/j.regg.2024.101585","url":null,"abstract":"","PeriodicalId":39958,"journal":{"name":"Revista Espanola de Geriatria y Gerontologia","volume":"60 3","pages":"Article 101585"},"PeriodicalIF":0.0,"publicationDate":"2024-12-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142855936","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-12-17DOI: 10.1016/j.regg.2024.101578
José María Ortega Morente, Leopoldo Bárcena Goitiandia, Salvador Cuevas Durón, José Luter Llanque Callata, Juliana Zuluaga Gómez, Johanna Pamela Vázquez Grande
{"title":"Neumovejiga y Neumaturia secundarios a Infecciones Enfisematosas del Tracto Urinario, signos poco comunes","authors":"José María Ortega Morente, Leopoldo Bárcena Goitiandia, Salvador Cuevas Durón, José Luter Llanque Callata, Juliana Zuluaga Gómez, Johanna Pamela Vázquez Grande","doi":"10.1016/j.regg.2024.101578","DOIUrl":"10.1016/j.regg.2024.101578","url":null,"abstract":"","PeriodicalId":39958,"journal":{"name":"Revista Espanola de Geriatria y Gerontologia","volume":"60 2","pages":"Article 101578"},"PeriodicalIF":0.0,"publicationDate":"2024-12-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142855876","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-12-17DOI: 10.1016/j.regg.2024.101582
Leonor Cuadra-Llopart , Teresa Pareja Sierra , Pilar Sáez-López , Iñigo Etxebarria-Foronda , José R. Caeiro Rey
Osteoporosis is a systemic skeletal disease characterized by low bone mass and deterioration of the microarchitecture, resulting in bone fragility and risk of fractures.
As the life expectancy of the population increases, fragility fractures are expected to become more common. Indeed, the incidence rate for major fracture (hip, vertebra, pelvis, etc.) is highest among the population of adults aged 80 and over. Despite this, in Spain, three out of four patients who have experienced a fragility fracture do not receive drug treatment for the secondary prevention of new fractures. Therefore, it is crucial to raise awareness among healthcare professionals of the need to assess imminent fracture risk in older patients who have already sustained a fragility fracture and to initiate a rapid, appropriate, effective, and safe secondary fracture prevention strategy.
The various clinical guidelines on secondary prevention of fragility fractures published to date do not reflect the heterogeneity of older adults.
The aim of this paper is to provide a brief description of the available scientific evidence on the efficacy and safety of pharmacological treatments for osteoporosis in older adults and to submit a position paper proposed by the Spanish Society of Osteoporotic Fractures (SEFRAOS), which places greater emphasis on the specifics of the approach to and treatment of older adults who have sustained a fragility fracture.
{"title":"Efficacy and safety of osteoporosis treatment in older adults. Approach for the secondary prevention of fractures in older populations. A proposal by SEFRAOS","authors":"Leonor Cuadra-Llopart , Teresa Pareja Sierra , Pilar Sáez-López , Iñigo Etxebarria-Foronda , José R. Caeiro Rey","doi":"10.1016/j.regg.2024.101582","DOIUrl":"10.1016/j.regg.2024.101582","url":null,"abstract":"<div><div>Osteoporosis is a systemic skeletal disease characterized by low bone mass and deterioration of the microarchitecture, resulting in bone fragility and risk of fractures.</div><div>As the life expectancy of the population increases, fragility fractures are expected to become more common. Indeed, the incidence rate for major fracture (hip, vertebra, pelvis, etc.) is highest among the population of adults aged 80 and over. Despite this, in Spain, three out of four patients who have experienced a fragility fracture do not receive drug treatment for the secondary prevention of new fractures. Therefore, it is crucial to raise awareness among healthcare professionals of the need to assess imminent fracture risk in older patients who have already sustained a fragility fracture and to initiate a rapid, appropriate, effective, and safe secondary fracture prevention strategy.</div><div>The various clinical guidelines on secondary prevention of fragility fractures published to date do not reflect the heterogeneity of older adults.</div><div>The aim of this paper is to provide a brief description of the available scientific evidence on the efficacy and safety of pharmacological treatments for osteoporosis in older adults and to submit a position paper proposed by the Spanish Society of Osteoporotic Fractures (SEFRAOS), which places greater emphasis on the specifics of the approach to and treatment of older adults who have sustained a fragility fracture.</div></div>","PeriodicalId":39958,"journal":{"name":"Revista Espanola de Geriatria y Gerontologia","volume":"60 3","pages":"Article 101582"},"PeriodicalIF":0.0,"publicationDate":"2024-12-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142855945","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Colitis colágena en una paciente octogenaria: a propósito de un caso","authors":"Constanza Sepúlveda Gallardo , Carlota Toapanta Gaibor , Emilio Sacanella Meseguer , Marta Arroyo-Huidobro","doi":"10.1016/j.regg.2024.101581","DOIUrl":"10.1016/j.regg.2024.101581","url":null,"abstract":"","PeriodicalId":39958,"journal":{"name":"Revista Espanola de Geriatria y Gerontologia","volume":"60 3","pages":"Article 101581"},"PeriodicalIF":0.0,"publicationDate":"2024-12-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142855939","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
扫码关注我们
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号