{"title":"Kanserin Rengi Nedir","authors":"Volkan Tatli, Oktay Üçer, T. Müezzinoğlu","doi":"10.4274/uob.795","DOIUrl":"https://doi.org/10.4274/uob.795","url":null,"abstract":"","PeriodicalId":40816,"journal":{"name":"Uroonkoloji Bulteni-Bulletin of Urooncology","volume":"16 1","pages":"8-11"},"PeriodicalIF":0.2,"publicationDate":"2017-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70978252","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Doğan Değer, Öner Deniz Aslan, Kaan Çömez, Feyzullah Eren, Sedik Adırbelli, Güven Aslan
{"title":"Mesane Kanseri Erken Tanı ve Tedavisinde Toplumsal Farkındalık: Yaş ve Eğitim Düzeyinin Önemi","authors":"Doğan Değer, Öner Deniz Aslan, Kaan Çömez, Feyzullah Eren, Sedik Adırbelli, Güven Aslan","doi":"10.4274/UOB.767","DOIUrl":"https://doi.org/10.4274/UOB.767","url":null,"abstract":"","PeriodicalId":40816,"journal":{"name":"Uroonkoloji Bulteni-Bulletin of Urooncology","volume":"16 1","pages":"12-16"},"PeriodicalIF":0.2,"publicationDate":"2017-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70978343","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Relationship between Bladder Cancer and Epigenetic Alterations","authors":"A. Ozen, A. Ülgen, C. Can","doi":"10.4274/uob.566","DOIUrl":"https://doi.org/10.4274/uob.566","url":null,"abstract":"","PeriodicalId":40816,"journal":{"name":"Uroonkoloji Bulteni-Bulletin of Urooncology","volume":"16 1","pages":"17-21"},"PeriodicalIF":0.2,"publicationDate":"2017-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47100684","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Risk Factors for Urothelial Cancers","authors":"U. Gul, Barış Kuzgunbay","doi":"10.4274/uob.554","DOIUrl":"https://doi.org/10.4274/uob.554","url":null,"abstract":"","PeriodicalId":40816,"journal":{"name":"Uroonkoloji Bulteni-Bulletin of Urooncology","volume":"15 1","pages":"154-158"},"PeriodicalIF":0.2,"publicationDate":"2016-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70976708","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
O. Cakmak, Sevgi Vermisli, O. Yalbuzdağ, D. Kahraman, S. Abdullazade
Benign mezenkimal tümörler tüm mesane tümörlerinin %1-5’ini oluşturur. Mesane leiomyomu mezenkimal kaynaklı nadir görülen benign tümördür (1,2). Semptomlar tümörün bulunduğu yer ve büyüklüğüne bağlı olarak değişiklik gösterebilir. Depolama semptomları, boşaltım semptomları ya da hematüri görülebilmektedir. Asemptomatik hastalarda radyolojik incelemeler sırasında insidental olarak da mesane leiomyomu saptanabilmektedir (1,3). Mesane leiomyomunun radyolojik değerlendirilmesi ultrasonografi (USG), bilgisayarlı tomografi (BT) veya manyetik rezonans inceleme (MRİ) ile yapılabilir (4). Tedavi modalitesi ise tümör lokalizasyonu ve boyutuna göre değişkenlik gösterebilir (2).
{"title":"Bladder Leiomyoma in Men: Report of Two Cases and Review of the Literatüre","authors":"O. Cakmak, Sevgi Vermisli, O. Yalbuzdağ, D. Kahraman, S. Abdullazade","doi":"10.4274/UOB.658","DOIUrl":"https://doi.org/10.4274/UOB.658","url":null,"abstract":"Benign mezenkimal tümörler tüm mesane tümörlerinin %1-5’ini oluşturur. Mesane leiomyomu mezenkimal kaynaklı nadir görülen benign tümördür (1,2). Semptomlar tümörün bulunduğu yer ve büyüklüğüne bağlı olarak değişiklik gösterebilir. Depolama semptomları, boşaltım semptomları ya da hematüri görülebilmektedir. Asemptomatik hastalarda radyolojik incelemeler sırasında insidental olarak da mesane leiomyomu saptanabilmektedir (1,3). Mesane leiomyomunun radyolojik değerlendirilmesi ultrasonografi (USG), bilgisayarlı tomografi (BT) veya manyetik rezonans inceleme (MRİ) ile yapılabilir (4). Tedavi modalitesi ise tümör lokalizasyonu ve boyutuna göre değişkenlik gösterebilir (2).","PeriodicalId":40816,"journal":{"name":"Uroonkoloji Bulteni-Bulletin of Urooncology","volume":"15 1","pages":"167-169"},"PeriodicalIF":0.2,"publicationDate":"2016-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70977251","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
E. Bagir, A. Açıkalın, V. Izol, G. Seydaoglu, S. Erdoğan
Objective: Prostate carcinoma (PC) is one of the most commonly diagnosed cancer types with significant rates of mortality and morbidity. The etiology of PC is not clear. Cytokine and mediators at the inflammatory pathway plays role at the various steps of the relation between chronic inflammation and cancer. The objective of this study is to determine if there is relationship between cyclooxygenase-2 (COX) apoptosis and angiogenesis in patients with PC. Materials and Methods: Sample of 49 cases who were at pathologic stage pT2 and underwent radical prostatectomy, were selected retrospectively between 2005-2010, from the archives of Pathology Department of Çukurova University Faculty of Medicine. Histologic slides of each case were reviewed for the diagnostic reassessment and graded by the Gleason scoring system. COX-2, vascular endothelial growth factor (VEGF), monoclonal antibody (M30) and bcl-2 were immunohistochemically applied to the cases and they were evaluated. Results: The mean age of the patients were 63.8. Twenty-one cases had their Gleason score ≤6 and 28 had their Gleason score ≥7. COX-2 expression was detected in 81.6% of cases. While COX-2 expression was significantly correlated with bcl-2 expression, there was no correlation between VEGF and COX-2 expression. Gleason score was negatively correlated with M30. It was detected that as COX-2 expression increased mean survival time significantly decreased. Conclusion: This study makes us think that in the PC carcinogenesis COX2 inhibits apoptosis rather than promoting angiogenesis. These results may offer new insights for the treatment strategies, also they may be useful for the prediction of clinical outcomes.
{"title":"Immunohistochemical Study of Cyclooxygenase-2 Expression in Prostate Carcinoma: It’s Relation with Apoptosis and Angiogenesis","authors":"E. Bagir, A. Açıkalın, V. Izol, G. Seydaoglu, S. Erdoğan","doi":"10.4274/UOB.708","DOIUrl":"https://doi.org/10.4274/UOB.708","url":null,"abstract":"Objective: Prostate carcinoma (PC) is one of the most commonly diagnosed cancer types with significant rates of mortality and morbidity. The etiology of PC is not clear. Cytokine and mediators at the inflammatory pathway plays role at the various steps of the relation between chronic inflammation and cancer. The objective of this study is to determine if there is relationship between cyclooxygenase-2 (COX) apoptosis and angiogenesis in patients with PC. Materials and Methods: Sample of 49 cases who were at pathologic stage pT2 and underwent radical prostatectomy, were selected retrospectively between 2005-2010, from the archives of Pathology Department of Çukurova University Faculty of Medicine. Histologic slides of each case were reviewed for the diagnostic reassessment and graded by the Gleason scoring system. COX-2, vascular endothelial growth factor (VEGF), monoclonal antibody (M30) and bcl-2 were immunohistochemically applied to the cases and they were evaluated. Results: The mean age of the patients were 63.8. Twenty-one cases had their Gleason score ≤6 and 28 had their Gleason score ≥7. COX-2 expression was detected in 81.6% of cases. While COX-2 expression was significantly correlated with bcl-2 expression, there was no correlation between VEGF and COX-2 expression. Gleason score was negatively correlated with M30. It was detected that as COX-2 expression increased mean survival time significantly decreased. Conclusion: This study makes us think that in the PC carcinogenesis COX2 inhibits apoptosis rather than promoting angiogenesis. These results may offer new insights for the treatment strategies, also they may be useful for the prediction of clinical outcomes.","PeriodicalId":40816,"journal":{"name":"Uroonkoloji Bulteni-Bulletin of Urooncology","volume":"15 1","pages":"144-147"},"PeriodicalIF":0.2,"publicationDate":"2016-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70977542","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. Çelik, Ozan Bozkurt, O. Demir, B. Tuna, K. Yorukoglu, G. Aslan
{"title":"Preoperative Factors Related to Stage and Grade Increase in D’Amico Low-Risk and Intermediate-Risk Group Patients","authors":"S. Çelik, Ozan Bozkurt, O. Demir, B. Tuna, K. Yorukoglu, G. Aslan","doi":"10.4274/UOB.738","DOIUrl":"https://doi.org/10.4274/UOB.738","url":null,"abstract":"","PeriodicalId":40816,"journal":{"name":"Uroonkoloji Bulteni-Bulletin of Urooncology","volume":"15 1","pages":"148-153"},"PeriodicalIF":0.2,"publicationDate":"2016-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70977880","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
G. Aslan, A. Cihan, O. Cinar, O. Demir, A. Kefi, I. Celebi
{"title":"Use of a Polytetrafluoroethylene Teflon Felt During Partial Nephrectomy","authors":"G. Aslan, A. Cihan, O. Cinar, O. Demir, A. Kefi, I. Celebi","doi":"10.4274/uob.743","DOIUrl":"https://doi.org/10.4274/uob.743","url":null,"abstract":"","PeriodicalId":40816,"journal":{"name":"Uroonkoloji Bulteni-Bulletin of Urooncology","volume":"15 1","pages":"140-143"},"PeriodicalIF":0.2,"publicationDate":"2016-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70978321","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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