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Cortical wave patterns in giant Dictyostelium cells 巨盘基骨细胞的皮质波型
Pub Date : 2016-05-24 DOI: 10.4108/EAI.3-12-2015.2262493
C. Beta
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引用次数: 0
A Dynamic Step-size Adaptation Roach Infestation Algorithm for Constrained Engineering Optimization Problems 约束工程优化问题的动态步长自适应蟑螂入侵算法
Pub Date : 2016-05-24 DOI: 10.4108/EAI.3-12-2015.2262602
I. Obagbuwa, M. Maharaj
Engineering problems belong to a large and complex category of optimization problems with non-linear and nonconvex functions; conventional methods are no longer sufficient to handle such problems. Meta-heuristic optimization algorithms have been proved in literature for being able to tackle complex problems. A new meta-heuristic algorithm called dynamic step-size roach infestation optimization algorithm based on searching behaviour of cockroaches was published recently. A Simple Euler method was introduced into a roach infestation optimization algorithm for the enhancement of swarm stability and to allow a balance of exploitation and exploration. The results of the experiments, show its superiority over the existing algorithms. In this work the same method was applied; and modified to solve a constrained engineering problem. The results obtained from simulation processes are close to those obtained by other meta-heuristic methods.
工程问题属于一类庞大而复杂的非线性非凸函数优化问题;传统的方法已不足以处理这类问题。元启发式优化算法已经在文献中被证明能够解决复杂问题。基于蟑螂的搜索行为,提出了一种新的元启发式算法——动态步长蟑螂入侵优化算法。在蟑螂侵害优化算法中引入了简单的欧拉法,增强了蚁群的稳定性,实现了开发与探索的平衡。实验结果表明,该算法优于现有算法。在这项工作中,采用了相同的方法;并修改以解决一个受限的工程问题。模拟过程得到的结果与其他元启发式方法得到的结果接近。
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引用次数: 1
Quantitative comparison of plasmodial networks of different slime molds 不同黏菌的质网定量比较
Pub Date : 2016-05-24 DOI: 10.4108/EAI.3-12-2015.2262420
Christian Westendorf, C. Gruber, M. Grube
We have compared Physarum polycephalum to other plasmodial slime molds, based on several properties of their respective phaneroplasmodia, as well as their chemotactic responses. This work was presented at PhysNet 2015.
我们比较了多头绒泡菌和其他疟原虫黏菌,基于它们各自的原疟原虫的几个特性,以及它们的趋化反应。这项工作在2015年的PhysNet上进行了展示。
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引用次数: 5
Metabolic Network Construction Using Ensemble Algorithms 基于集成算法的代谢网络构建
Pub Date : 2016-05-24 DOI: 10.4108/EAI.3-12-2015.2262392
S. Kim, Joohyoung Lee, H. Jang, Xiang Zhang
One of the most important and challenging "knowledge extraction" tasks in bioinformatics is the reverse engineering of genes, proteins, and metabolites networks from biological data. Gaussian graphical models (GGMs) have been proven to be a very powerful formalism to infer biological networks. Standard GGM selection techniques can unfortunately not be used in the "small N, large P" data setting. Various methods to overcome this issue have been developed based on regularized estimation, partial least squares method, and limited-order partial correlation graphs. Several studies compared the performances among several network construction algorithms, such as PLSR, SCE, and ES, ICR and PCR, Ridge regression, Lasso and adaptive Lasso, to see which method is the best for biological network constructions. Each comparison analysis resulted in that each construction method has its own advantages as well as disadvantages according to different circumstances, such as the network complexity. However, it is almost impossible to recognize the complexity of the network before estimation. Thus, we develop an Ensemble method which is model averaging to construct a metabolic network. Our simulation studies show that the ensemble averaging based network construction has F1 score larger than these of other methods except only for Adaptive Lasso, reflecting its ability to account for uncertainty of network complexity.
生物信息学中最重要和最具挑战性的“知识提取”任务之一是从生物数据中对基因、蛋白质和代谢物网络进行逆向工程。高斯图形模型(GGMs)已被证明是一种非常强大的形式来推断生物网络。不幸的是,标准的GGM选择技术不能用于“小N,大P”的数据集。基于正则化估计、偏最小二乘法和有限阶偏相关图,已经开发了各种方法来克服这个问题。一些研究比较了几种网络构建算法的性能,如PLSR、SCE和ES、ICR和PCR、Ridge回归、Lasso和adaptive Lasso,以了解哪种方法最适合生物网络构建。每一种对比分析的结果是,根据网络复杂程度等不同的情况,每种构建方法都有各自的优点和缺点。然而,在估计之前几乎不可能识别出网络的复杂性。因此,我们开发了一种模型平均的集成方法来构建一个代谢网络。我们的仿真研究表明,除了自适应Lasso之外,基于集合平均的网络构建的F1得分高于其他方法,反映了其考虑网络复杂性不确定性的能力。
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引用次数: 0
An Open Agent-Based Model to Simulate the Effect of WOM Marketing Campaigns 一个基于开放代理的模型来模拟口碑营销活动的效果
Pub Date : 2016-05-24 DOI: 10.4108/EAI.3-12-2015.2262533
Paul Leger, Manuela López, Carmen Hidalgo-Alcázar, Hiroaki Fukuda
Word-Of-Mouth (WOM) is the opinion of consumers about a product. There is currently a clear trend in the use of WOM to diffuse information about a new product, known as WOM marketing campaigns. Marketing researchers are studying the impact of the different types of these campaigns has. The difficulty in getting data and isolating the effect that is analyzed limits the research of marketers in this topic. Lastly, some simulation models based on agents have overcome previous difficulty. However, these models are ad-hoc and specific solutions for every study. This poster proposes an open implementation of an agent-based model to simulate different scenarios of WOM marketing campaigns. Through customizations, this proposal will allow marketing researchers to test WOM marketing campaigns in different scenarios.
口碑(Word-Of-Mouth)是消费者对产品的看法。目前有一个明显的趋势是利用口碑传播新产品的信息,称为口碑营销活动。市场研究人员正在研究这些活动的不同类型所产生的影响。难以获得数据和隔离分析的效果限制了营销人员在这一主题的研究。最后,一些基于智能体的仿真模型克服了以往的困难。然而,这些模型对于每个研究都是特别的和特定的解决方案。这张海报提出了一个基于代理的模型的开放实现,以模拟不同场景的口碑营销活动。通过定制,该提案将允许营销研究人员在不同的场景中测试口碑营销活动。
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引用次数: 0
Clustering of Functional Data by Band Depth 基于频带深度的功能数据聚类
Pub Date : 2016-05-24 DOI: 10.4108/EAI.3-12-2015.2262364
A. M. Kwon, Ouyang Ming
The notion of data depth is a generalization of order statistics, ranks, and medians in one-dimensional space to multi-dimensional space. Band depth is a depth measure of functional data. A few articles in the literature emerged in recent years that used band depth to analyze functional data. The present work is the first attempt to develop a non-parametric clustering method based on band depth. Three definitions of band depth are compared, a few combinations of clustering strategies are employed, and band depth clustering is applied to DNA microarray data of yeast cell cycle. The results show that band depth clustering is efficient and robust.
数据深度的概念是将一维空间中的顺序统计量、秩和中位数推广到多维空间。波段深度是功能数据的深度度量。近年来,文献中出现了一些使用波段深度分析功能数据的文章。本文首次尝试了基于频带深度的非参数聚类方法。比较了三种波段深度的定义,采用了几种不同的聚类策略组合,并将波段深度聚类应用于酵母细胞周期的DNA芯片数据。结果表明,该算法具有较好的鲁棒性和有效性。
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引用次数: 4
A Low-Cost Bio-Imaging and Incubation System 低成本生物成像和孵化系统
Pub Date : 2016-05-24 DOI: 10.4108/EAI.3-12-2015.2262490
E. Bernitt, Christina Oettmeier, Daniel Henrichs, H. Döbereiner
Here we describe an integrated system for biological experiments on dynamic processes on the millimeter length scale. The system permits live imaging under controlled environmental conditions using low-cost technology that is easy to implement. This work was presented at PhysNet 2015.
在这里,我们描述了一个集成系统的动态过程的生物实验在毫米长度尺度。该系统允许在受控环境条件下使用低成本技术进行实时成像,易于实现。这项工作在2015年的PhysNet上进行了展示。
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引用次数: 1
Towards a mesoscopic-level canonical circuit definition for visual cortical processing 视觉皮层加工的中观水平规范电路定义
Pub Date : 2016-05-24 DOI: 10.4108/EAI.3-12-2015.2262448
Georg Layher, T. Brosch, H. Neumann
The mammalian cortex is organized into different layers which are characterized by different cell clusterings and prominent lateral fiber connections. As a primary organizational principle driving signal inputs enter mainly at layer IV, feedforward output activations leave at superficial, while modulating feedback signals leave at deep layers. Likewise, modulatory input signals from other areas mainly enter in superficial layers. Based on such compartmental structure we suggest an abstract formulation of composite structural elements which form building blocks to define canonical elements for columnar computation in cortex. There is evidence that the brain makes use of an operational set of canonical computations, like, e.g., sensory signal filtering, reentrant response gain enhancement, noise suppression, and normalization. As a further abstraction, we define a dynamical three-stage model of processing in a cortical column for processing that allows to investigate their dynamic response properties. Some examples of the analysis of the dynamics are presented together with some simulation results that highlight properties of visual processing in model cortices. Finally, we demonstrate how learning mechanisms that adapt the connection weights can be incorporated in such a scheme capable to form feature representations and functional sub-networks in an adaptive fashion.
哺乳动物皮层被组织成不同的层,其特征是不同的细胞簇和突出的侧纤维连接。作为驱动信号输入主要在第四层进入的主要组织原理,前馈输出激活留在表层,而调制反馈信号留在深层。同样,来自其他区域的调制输入信号也主要从表层进入。基于这种隔室结构,我们提出了一种抽象的复合结构元素公式,这些元素构成了构建块,以定义皮层柱状计算的规范元素。有证据表明,大脑利用了一套可操作的规范计算,例如,感觉信号滤波、可重入响应增益增强、噪声抑制和归一化。作为进一步的抽象,我们定义了一个动态的皮层柱处理的三阶段模型,允许研究它们的动态响应特性。给出了一些动力学分析的例子,并给出了一些仿真结果,这些结果突出了模型皮层中视觉处理的特性。最后,我们演示了如何将适应连接权重的学习机制整合到能够以自适应方式形成特征表示和功能子网络的方案中。
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引用次数: 3
Analysis on the exploratory behavior of the Physarum plasmodium in an open space 开放空间绒泡菌的探索行为分析
Pub Date : 2016-05-24 DOI: 10.4108/EAI.3-12-2015.2262478
T. Shirakawa, Hiroshi Sato, Ryota Ohno
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引用次数: 0
Growth pattern of Physarum polycephalum during starvation 饥饿期间多头绒泡菌的生长模式
Pub Date : 2016-05-24 DOI: 10.4108/EAI.3-12-2015.2262481
Jonghyun Lee, Christina Oettmeier, H. Döbereiner
We describe a new growth pattern where globular moving fragments are formed instead of networks.
我们描述了一种新的增长模式,其中球状移动碎片形成,而不是网络。
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引用次数: 1
期刊
International Conference on Bio-inspired Information and Communications Technologies
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