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2008 International Seminar on Future BioMedical Information Engineering最新文献

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Research on Self-Tuning Observer-Compensator Control Scheme and Its Application 自整定观测器-补偿器控制方案及其应用研究
Pub Date : 2008-12-18 DOI: 10.1109/FBIE.2008.93
Linhui Liu, Jie Chen, Lixin Xu
The control strategy of self-tuning observer-compensator for time lag systems is discussed, makes it applied to ammonia plant synthesizing section's hydrogen-nitrogen ratio control, which makes a great successes. The qualified rate of hydrogen-nitrogen ratio increased to about 90% from the original 50% or so.
讨论了时滞系统自整定观测器-补偿器的控制策略,并将其应用于氨装置合成环节的氢氮比控制,取得了很大的成功。氢氮比合格率由原来的50%左右提高到90%左右。
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引用次数: 0
Medical Image Segmentation Based on Modified Ant Colony Algorithm with GVF Snake Model 基于GVF Snake模型的改进蚁群算法医学图像分割
Pub Date : 2008-12-18 DOI: 10.1109/FBIE.2008.110
Lei Li, Yuemei Ren, Xiangpu Gong
In order to distinguish normal tissues and abnormal pathological changes in the clinic diagnose and pathology, it is required to segment the medical images. The snake model is an important method of getting the contour of the object in the image segmentation. However, it has many defects in some fields such as concavity processing, local optimization, convergence speed and segmentation precision. Aiming at the problem existing in the snake model about falling into its local optimization, a new method of medical image segmentation based on modified ant colony algorithm with GVF snake model is proposed. With adding crowded degree function to ant colony algorithm, the overall traversal ability is increased and the capacity of finding optimal solution is enhanced. The contrast experiments proved that the method in this paper is superior to the segmentation using snake model only in convergence speed, global search performance, and the precision of finding global optimal solution.
为了在临床诊断和病理中区分正常组织和异常病理变化,需要对医学图像进行分割。蛇形模型是图像分割中获取目标轮廓的重要方法。然而,它在凹性处理、局部优化、收敛速度和分割精度等方面存在许多缺陷。针对蛇形模型陷入局部最优的问题,提出了一种基于改进蚁群算法的GVF蛇形模型医学图像分割新方法。在蚁群算法中加入拥挤度函数,提高了蚁群算法的整体遍历能力,增强了算法寻找最优解的能力。对比实验证明,本文方法仅在收敛速度、全局搜索性能和寻找全局最优解的精度上优于使用snake模型的分割方法。
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引用次数: 11
Electrical Load Forecasting Based on Fuzzy Wavelet Neural Networks 基于模糊小波神经网络的电力负荷预测
Pub Date : 2008-12-18 DOI: 10.1109/FBIE.2008.67
Xiaoxia Li, Yanli Zhang, Liya Cai
In view of the defects of the prediction model based on neural network, such as when doing prediction of nonlinear sequence, it is likely to fall into local hypo-strong point, and the rate of training is very slow, based on the traditional prediction model using neural network, a novel short-term electrical load prediction model based on fuzzy wavelet neural networks (FWN) is presented in this paper. The prediction effect of wavelet neural network prediction model is proved in Matlab7.0 simulation environment. A better prediction result is gained, and the defect of falling into local hypo-strongpoint is overcome, at the same time, the rate of training is raised compared with the prediction model based on neural network. The calculation result shows that the presented model is effective.
针对基于神经网络的预测模型在对非线性序列进行预测时容易陷入局部次强点、训练速度慢等缺陷,在传统神经网络预测模型的基础上,提出了一种基于模糊小波神经网络(FWN)的短期电力负荷预测模型。在Matlab7.0仿真环境下验证了小波神经网络预测模型的预测效果。得到了较好的预测结果,克服了局部陷入次强点的缺陷,同时与基于神经网络的预测模型相比,提高了训练率。计算结果表明,该模型是有效的。
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引用次数: 1
Experimental Study of Human Bone Marrow Mesenchymal Stem Cells Transfected with Vascular Endothelial Growth Factor Gene in Vitro 人骨髓间充质干细胞体外转染血管内皮生长因子基因的实验研究
Pub Date : 2008-12-18 DOI: 10.1109/FBIE.2008.19
Dewu Liu, Xiangrong Zhang, Guanghua Guo, Yan Peng
Vascular endothelial growth factor 165 (VEGF165) is one of the most prominent vascular growth factors that has the potential to accelerate wound healing by promoting the regeneration of capillary vasculature. However, the short biological half-live of growth factors may impose severe restraints on their clinical applications. Here, we investigate the feasibility and safety of human bone marrow derived mesenchymal stem cells (MSCs) transfected with VEGF165 gene so as to provide a new method for clinical skin repair in the future. The MSCs were harvested, isolated and purified by combining density gradient centrifugation with adhering method. The pShuttle-CMV/VEGF165 was introduced into cultured MSCs through liposome-mediated transfection. The VEGF165 gene and protein expression in transfected MSCs and untransfected MSCs were determined by reverse transcription-polymerase chain reaction (RT-PCR), Enzyme-linked Immunoadsorbent Assay (ELISA) and western blot analysis respectively. We found that the expression of VEGF165 mRNA and protein in transfected MSCs were much higher than those in the untransfected MSCs. These results suggest that human bone marrow derived mesenchymal stem cells can be successfully transfected with vascular endothelial growth factor 165 gene mediated by liposome in vitro. The present study has laid a foundation for potential use of VEGF165 gene transfection to accelerate the vascularization of tissue engineered skins grafting.
血管内皮生长因子165 (VEGF165)是最重要的血管生长因子之一,具有通过促进毛细血管再生来加速伤口愈合的潜力。然而,生长因子的生物半衰期短,严重制约了其临床应用。本研究旨在探讨转染VEGF165基因的人骨髓间充质干细胞(MSCs)的可行性和安全性,以期为今后临床皮肤修复提供一种新的方法。采用密度梯度离心和黏附相结合的方法分离纯化MSCs。通过脂质体介导转染将pShuttle-CMV/VEGF165引入培养的MSCs。分别采用逆转录聚合酶链反应(RT-PCR)、酶联免疫吸附试验(ELISA)和western blot检测转染MSCs和未转染MSCs中VEGF165基因和蛋白的表达。我们发现转染的MSCs中VEGF165 mRNA和蛋白的表达量远高于未转染的MSCs。结果表明,脂质体介导的血管内皮生长因子165基因可以成功转染人骨髓间充质干细胞。本研究为利用VEGF165基因转染加速组织工程皮肤移植血管化奠定了基础。
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引用次数: 1
Research on the Matching Algorithm of Semantic Web Service in Pervasive Environments 普适环境下语义Web服务匹配算法研究
Pub Date : 2008-12-18 DOI: 10.1109/FBIE.2008.88
Cuncun Wei
With the dramatic increasing number of available Web services, how to locate the right services is becoming a big challenge in pervasive environments. The Web services discovery mechanism of UDDI based on keywords and simple classification can not meet the current needs. A semantic distance between ontology concepts is defined to calculate the similarity between ontology concepts. Based on the similarity, a new semantic Web service matching algorithm is proposed. The evaluations of the experimental results have indicated that the results correlate well with this algorithm under the pervasive environment.
随着可用Web服务数量的急剧增加,如何在普及环境中定位正确的服务正成为一个巨大的挑战。UDDI基于关键字和简单分类的Web服务发现机制已不能满足当前的需求。定义本体概念之间的语义距离,计算本体概念之间的相似度。基于相似度,提出了一种新的语义Web服务匹配算法。实验结果表明,在普适环境下,该算法与实验结果具有良好的相关性。
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引用次数: 0
Simple and Robust Digital Holography Used for Phase Imaging 用于相位成像的简单鲁棒数字全息
Pub Date : 2008-12-18 DOI: 10.1109/FBIE.2008.117
Jingbo Liu, Xiufa Song, Min Huang, Huaying Wang
Digital holography is a digitized holography, which is very suitable for phase imaging of microscopic object. An off-axis lensless Fourier transform digital holographic system is built. The recording and numerical reconstruction of digital hologram is analyzed. The model of phase aberration in numerical reconstruction is presented. Experimental investigations have been performed for a USAF test target. The accurate phase image is obtained by an automatic phase aberration compensation procedure. The lateral resolution of 2.76 mum and the axial resolution of no larger than 10 nm have been achieved experimentally. The results are coincident with the theoretical predictions. Also, the height profiles of the test target is obtained and given.
数字全息术是一种数字化全息术,非常适合于显微物体的相位成像。建立了离轴无透镜傅里叶变换数字全息系统。分析了数字全息图的记录和数字重建。提出了数值重建中相位像差的模型。对美国空军试验靶进行了实验研究。通过相位像差自动补偿程序获得精确的相位图像。实验得到了2.76 nm的横向分辨率和不大于10 nm的轴向分辨率。结果与理论预测一致。并给出了试验目标的高度分布图。
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引用次数: 2
A Trusted Affective Model Approach to Proactive Health Monitoring System 基于可信情感模型的主动健康监测系统
Pub Date : 2008-12-18 DOI: 10.1109/FBIE.2008.52
Xu Chao, Feng Zhiyong
How to intensify real-time health monitoring to patients effectively and correctly is a crucial and acknowledged precondition for the adoption of new intelligent technologies such as affective and proactive computing. This paper proposed an overview of the approaches to build a reliable affective model on the basis of affective trust theory for high accurate health monitoring systems. Proactive environment was applied for health monitor to provide ideal environments and achieve monitor tasks by sensor or machine vision so as to minimize mistakes for patients in advance. A central design for trusted monitor report was how to capture patient's affective expressions. In general, a person-independent affective model based on swift trust was proposed for specific patient's facial expressions and biomedical signals were caught by sensor for swift trusted comparison with emotions. Based on cognitive analysis, the model could help analyze and void the crucial mistaken reports for real-time health monitoring systems.
如何有效、正确地加强对患者的实时健康监测是采用情感、主动计算等新型智能技术的关键和公认的前提。本文综述了基于情感信任理论构建高精度健康监测系统可靠情感模型的方法。将主动环境应用于健康监测,提供理想的环境,通过传感器或机器视觉实现监测任务,提前减少患者的失误。可信监护报告的核心设计是如何捕捉患者的情感表达。总的来说,针对特定患者的面部表情,提出了一种基于快速信任的独立于人的情感模型,通过传感器捕捉生物医学信号与情绪进行快速信任比较。基于认知分析,该模型可以帮助实时健康监测系统分析和消除关键错误报告。
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引用次数: 4
A Novel Simple Distributed Algorithm for Cluster Organization of Wireless Sensor Networks 一种新的简单分布式无线传感器网络聚类组织算法
Pub Date : 2008-12-18 DOI: 10.1109/FBIE.2008.100
Nan Hua, Yi Guo
This paper proposes an innovative distributed algorithm for cluster organization of wireless sensor networks (WSN), named DSCO. Simple logic, connectionless information exchange and asynchronism are prominent features of the algorithm. DSCO involves three correlative processes: cluster organization, cluster reorganization and cluster self-healing. The process of cluster organization is the basic process of DSCO, which adopts random backoff strategy; the cluster reorganization and cluster self-healing processes are recursion of the former, which effectively simplifies the design of the algorithm. Furthermore, DSCO furthest isolates nodes and clusters, and reduces the reliance of global information to minimum, which is useful to reduce the pressure of data storage and processing in nodes, lessen the network traffic and enhance the anti-destroy ability of WSN. The algorithm simulation illustrates that DSCO can get fast clustering speed and uniform distribution of cluster nodes, proves its good performance on clustering rate and topology control, and shows good adaptability to large-scale WSN.
本文提出了一种新颖的用于无线传感器网络(WSN)集群组织的分布式算法DSCO。简单的逻辑、无连接的信息交换和异步性是该算法的突出特点。DSCO涉及三个相互关联的过程:集群组织、集群重组和集群自愈。集群组织过程是DSCO的基本过程,采用随机后退策略;聚类重组和聚类自愈过程是前者的递归,有效地简化了算法的设计。此外,DSCO最大程度地隔离了节点和集群,将全局信息的依赖降到最低,有助于降低节点数据存储和处理的压力,减少网络流量,增强WSN的抗破坏能力。算法仿真结果表明,DSCO能获得较快的聚类速度和均匀的聚类节点分布,在聚类速率和拓扑控制方面具有良好的性能,对大规模WSN具有良好的适应性。
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引用次数: 0
Strategies for Implementing SSL on Embedded System 嵌入式系统中SSL的实现策略
Pub Date : 2008-12-18 DOI: 10.1109/FBIE.2008.81
Qianqian Ge, Feng Chen
With the hackers' attacks changing from the desktop to embedded applications, hardware and software security decision leads the whole design of the embedded systems. This paper describes from the characteristics of SSL protocol, concludes two aspects from external hardware cooperation and internal structure optimizations. It presents the strategies of implementing SSL protocol on both software and hardware design.
随着黑客的攻击从桌面转向嵌入式应用,硬件和软件的安全决策主导着嵌入式系统的整体设计。本文从SSL协议的特点出发,从外部硬件协作和内部结构优化两个方面进行了阐述。从软件设计和硬件设计两方面介绍了SSL协议的实现策略。
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引用次数: 2
EPR Management System Development Based on B/S Architecture 基于B/S架构的EPR管理系统开发
Pub Date : 2008-12-18 DOI: 10.1109/FBIE.2008.78
Yan Cao, Lina Yang, Yanli Yang
As electronic patient record (EPR) is the basis of clinical information and the core of a hospital information system (HIS), the research on EPR is an important element of HIS and digital hospital construction. Based on B/S architecture, a three-layer EPR management system is presented. Its expandable, maintainable and secure B/S system architecture is cost-effective and is developed with Eclipse platform. The dataflow and activities at a hospital are analyzed. Based on the function and operation analysis of the clinical department in a hospital, the database structure for the EPR management system is designed using E-R charts. The functioning process of the server in the B/S architecture is discussed. The server is developed with the components registered in Struts-config.xml file. At the client, JSP pages are created with dreamweaver. The prototype system is tested by test run and its correctness is validated.
电子病历是临床信息的基础,是医院信息系统的核心,对电子病历的研究是医院信息系统和数字化医院建设的重要内容。提出了一个基于B/S架构的三层EPR管理系统。其可扩展、可维护和安全的B/S系统架构具有成本效益,并在Eclipse平台上开发。分析了医院的数据流和活动。在分析某医院临床科室功能和运行情况的基础上,采用E-R图设计了EPR管理系统的数据库结构。讨论了B/S架构下服务器的工作过程。服务器是使用在Struts-config.xml文件中注册的组件开发的。在客户端,JSP页面是用dreamweaver创建的。通过试运行对原型系统进行了验证,验证了其正确性。
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引用次数: 2
期刊
2008 International Seminar on Future BioMedical Information Engineering
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