Pub Date : 2020-12-19DOI: 10.32448/entupdates.839113
M. Kar, M. Altıntaş
Objective: In this study, we aimed to investigate the effectiveness of the Epley maneuver performed without any additional medical treatment on symptoms and quality of life in patients diagnosed with canalithiasis type posterior canal BPPV with the Dix- Hallpike (DH) test in two District Hospitals of Antalya -Turkey. Methods: A total of 55 patients who were admitted to the ENT Departments Kumluca and Serik State Hospitals, Antalya between November 2019 and June 2020 with complaining of positional vertigo who were diagnosed as posterior canal BPPV with the Dix Hallpike (DH) test was included in this study. Results: Fifty-five cases with dizziness and vertigo complaints enrolled in our study. Thirty-four of the patients were male (%43.6), and 21 cases were female (%56.4). The ages of the patients were between 32 and 81with an average of 52.4±13.3 years. Statistically significant improvement was obtained at Vertigo Symptom Scale, Vertigo Dizziness Imbalance Symptom Scale, and Vertigo, Dizziness Imbalance health-related quality of life scale after the application of Epley maneuver Conclusion: In our study, Epley maneuver efficacy without any additional medical treatment was found to be very high in BPPV patients. As a result of this study, we wanted to emphasize that medical treatment to every patient presenting with dizziness and vertigo complaints is not a correct approach.
{"title":"Effects the Epley Maneuver on the Symptoms and Quality of Life Levels in Posterior Canal Benign Paroxysmal Positional Vertigo: Two Antalya District Hospitals Experience","authors":"M. Kar, M. Altıntaş","doi":"10.32448/entupdates.839113","DOIUrl":"https://doi.org/10.32448/entupdates.839113","url":null,"abstract":"Objective: In this study, we aimed to investigate the effectiveness of the Epley maneuver performed without any additional medical treatment on symptoms and quality of life in patients diagnosed with canalithiasis type posterior canal BPPV with the Dix- Hallpike (DH) test in two District Hospitals of Antalya -Turkey. Methods: A total of 55 patients who were admitted to the ENT Departments Kumluca and Serik State Hospitals, Antalya between November 2019 and June 2020 with complaining of positional vertigo who were diagnosed as posterior canal BPPV with the Dix Hallpike (DH) test was included in this study. Results: Fifty-five cases with dizziness and vertigo complaints enrolled in our study. Thirty-four of the patients were male (%43.6), and 21 cases were female (%56.4). The ages of the patients were between 32 and 81with an average of 52.4±13.3 years. Statistically significant improvement was obtained at Vertigo Symptom Scale, Vertigo Dizziness Imbalance Symptom Scale, and Vertigo, Dizziness Imbalance health-related quality of life scale after the application of Epley maneuver Conclusion: In our study, Epley maneuver efficacy without any additional medical treatment was found to be very high in BPPV patients. As a result of this study, we wanted to emphasize that medical treatment to every patient presenting with dizziness and vertigo complaints is not a correct approach.","PeriodicalId":41744,"journal":{"name":"ENT Updates","volume":null,"pages":null},"PeriodicalIF":0.1,"publicationDate":"2020-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48847820","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-12-17DOI: 10.32448/entupdates.814569
E. Ocak, M. Uyar, Deniz Kocaöz, Emre Mirici, A. Acar
Objective: To investigate the role of vitamin D on the etiology and the prognosis of Bell’s Palsy (BP). Methods: A prospective controlled clinical study was conducted on patients diagnosed as BP and healthy volunteers as control group. Vitamin D levels were measured in all subjects. In a homogenous group, effects of vitamin D on the etiology and prognosis were evaluated according to House-Brackmann (HB) grades of participants. Results: Vitamin D levels were similar in the BP and control groups. In BP group, patients with advanced HB grades had lower vitamin D levels. Moreover poorer outcomes (p=0.01) were achieved in patients who had <10ng/ml vitamin D, regardless the initial HB grade. Conclusion: Our results demonstrated a possible role of vitamin D levels on the prognosis of BP. Lower vitamin D levels may have a negative effect on recovery particularly in patients with advanced grades.
{"title":"Role of Vitamin D Deficiency on The Onset and Prognosis of Bell’s Palsy","authors":"E. Ocak, M. Uyar, Deniz Kocaöz, Emre Mirici, A. Acar","doi":"10.32448/entupdates.814569","DOIUrl":"https://doi.org/10.32448/entupdates.814569","url":null,"abstract":"Objective: To investigate the role of vitamin D on the etiology and the prognosis of Bell’s Palsy (BP). Methods: A prospective controlled clinical study was conducted on patients diagnosed as BP and healthy volunteers as control group. Vitamin D levels were measured in all subjects. In a homogenous group, effects of vitamin D on the etiology and prognosis were evaluated according to House-Brackmann (HB) grades of participants. Results: Vitamin D levels were similar in the BP and control groups. In BP group, patients with advanced HB grades had lower vitamin D levels. Moreover poorer outcomes (p=0.01) were achieved in patients who had <10ng/ml vitamin D, regardless the initial HB grade. Conclusion: Our results demonstrated a possible role of vitamin D levels on the prognosis of BP. Lower vitamin D levels may have a negative effect on recovery particularly in patients with advanced grades.","PeriodicalId":41744,"journal":{"name":"ENT Updates","volume":null,"pages":null},"PeriodicalIF":0.1,"publicationDate":"2020-12-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46108103","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-12-17DOI: 10.32448/entupdates.828992
Abdulvahap Akyiğit, E. Keleş, T. Karlıdağ, Į. Kaygusuz, Mehmet Sali̇h Yağmahan, Ş. Yalçın
{"title":"ANALYSIS OF PATIENTS WITH SEPTAL ABSCESS CAUSED BY ELECTROCAUTERISATION OF THE NASAL SEPTUM","authors":"Abdulvahap Akyiğit, E. Keleş, T. Karlıdağ, Į. Kaygusuz, Mehmet Sali̇h Yağmahan, Ş. Yalçın","doi":"10.32448/entupdates.828992","DOIUrl":"https://doi.org/10.32448/entupdates.828992","url":null,"abstract":"","PeriodicalId":41744,"journal":{"name":"ENT Updates","volume":null,"pages":null},"PeriodicalIF":0.1,"publicationDate":"2020-12-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44725532","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-12-09DOI: 10.32448/entupdates.827544
E. Özgür, Börte Gürbüz Özgür
Objective: Stuttering is a communication disorder that can affect an individual’s life in many ways. This study aimed to evaluate the effects of stuttering on children and adolescents’ health-related quality of life (HRQoL). Methods: This is a cross-sectional type of case-control study. Thirty-six children and adolescents diagnosed with stuttering according to DSM-5 and 37 age- and gen-der-matched healthy children and adolescents were included in the study. The child and adolescent’s HRQoL in both groups was evaluated using the KIDSCREEN-52 self and proxy reports. Results: No significant difference was observed in the physical well-being, psychological well-being, moods and emotions, self-perception, autonomy, parental relationships and home life, financial resources, social support and peers, school environment, social acceptance-bul-lying dimensions in the KIDSCREEN-52 questionnaire between-group comparison of both report and proxy results. The parental score reports were found to be statistically significantly lower than the children with stuttering in social acceptance-bullying dimension. In con-trast, the children’s scores in the dimensions of physical well-being, self-perception, parental relationships and home life, social support and peers and school environment were found to be statistically significantly lower than their parents. Conclusion: According to the study results, it was observed that the HRQoL of children between the ages of 8-18 who stutter was not different from healthy children. Since factors affecting the HRQoL of children may be affected by developmental processes, the necessity of longitudinal assessment of the HRQoL of stuttering children should be considered.
{"title":"Health-related quality of life based on KIDSCREEN-52 in stuttering children and adolescents","authors":"E. Özgür, Börte Gürbüz Özgür","doi":"10.32448/entupdates.827544","DOIUrl":"https://doi.org/10.32448/entupdates.827544","url":null,"abstract":"Objective: Stuttering is a communication disorder that can affect an individual’s life in many ways. This study aimed to evaluate the effects of stuttering on children and adolescents’ health-related quality of life (HRQoL). Methods: This is a cross-sectional type of case-control study. Thirty-six children and adolescents diagnosed with stuttering according to DSM-5 and 37 age- and gen-der-matched healthy children and adolescents were included in the study. The child and adolescent’s HRQoL in both groups was evaluated using the KIDSCREEN-52 self and proxy reports. Results: No significant difference was observed in the physical well-being, psychological well-being, moods and emotions, self-perception, autonomy, parental relationships and home life, financial resources, social support and peers, school environment, social acceptance-bul-lying dimensions in the KIDSCREEN-52 questionnaire between-group comparison of both report and proxy results. The parental score reports were found to be statistically significantly lower than the children with stuttering in social acceptance-bullying dimension. In con-trast, the children’s scores in the dimensions of physical well-being, self-perception, parental relationships and home life, social support and peers and school environment were found to be statistically significantly lower than their parents. Conclusion: According to the study results, it was observed that the HRQoL of children between the ages of 8-18 who stutter was not different from healthy children. Since factors affecting the HRQoL of children may be affected by developmental processes, the necessity of longitudinal assessment of the HRQoL of stuttering children should be considered.","PeriodicalId":41744,"journal":{"name":"ENT Updates","volume":null,"pages":null},"PeriodicalIF":0.1,"publicationDate":"2020-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48172959","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-12-09DOI: 10.32448/entupdates.825640
Muge Ozcelik Korkmaz, B. Sevimli Dikicier, N. Ilhan, Mehmet Güven
{"title":"Dermographic Properties And Correlation of Oral Mucosa Lesions with Dermatological Preliminary Diagnosis","authors":"Muge Ozcelik Korkmaz, B. Sevimli Dikicier, N. Ilhan, Mehmet Güven","doi":"10.32448/entupdates.825640","DOIUrl":"https://doi.org/10.32448/entupdates.825640","url":null,"abstract":"","PeriodicalId":41744,"journal":{"name":"ENT Updates","volume":null,"pages":null},"PeriodicalIF":0.1,"publicationDate":"2020-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69672094","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-11-28DOI: 10.32448/entupdates.798459
Sami Engin Muz, Mahmut Huntürk Atilla
Objective: The purpose of this study was to observe and evaluate the possible complications of Transoral Endona-sal-Controlled Combined Endoscopic Adenoidectomy (TECCA) as a subtype of power-assisted endoscopic adenoidectomy (PAEA) in pediatric patients. Methods: Sixty-seven children aged between 2 and 12 years who had been diagnosed with adenoid hypertrophy and underwent TECCA from April 2013 to December 2016 as a single procedure (without myringotomy or any kind of tonsil surgery at the same time) were included. Preoperative risk assessment results and intraoperative and post-operative complications were evaluated. Results: Intraoperative and early post-operative bleeding was observed in four (5.97%) patients. There was no post-operative complication except for bleeding and no patients were found to have residual adenoid tissue during the six-month post-operative follow-up period. Conclusion: Endonasal endoscopic control during adenoidectomy helps to identify vascular structures that would normally be at risk of being injured with blind resection. Endoscopic viewing also enables complete removal of intranasal adenoid tissue without significant prolongation in operation time.
{"title":"COMPLICATIONS OF TRANSORAL ENDONASAL-CONTROLLED COMBINED ENDOSCOPIC ADENOIDECTOMY","authors":"Sami Engin Muz, Mahmut Huntürk Atilla","doi":"10.32448/entupdates.798459","DOIUrl":"https://doi.org/10.32448/entupdates.798459","url":null,"abstract":"Objective: The purpose of this study was to observe and evaluate the possible complications of Transoral Endona-sal-Controlled Combined Endoscopic Adenoidectomy (TECCA) as a subtype of power-assisted endoscopic adenoidectomy (PAEA) in pediatric patients. Methods: Sixty-seven children aged between 2 and 12 years who had been diagnosed with adenoid hypertrophy and underwent TECCA from April 2013 to December 2016 as a single procedure (without myringotomy or any kind of tonsil surgery at the same time) were included. Preoperative risk assessment results and intraoperative and post-operative complications were evaluated. Results: Intraoperative and early post-operative bleeding was observed in four (5.97%) patients. There was no post-operative complication except for bleeding and no patients were found to have residual adenoid tissue during the six-month post-operative follow-up period. Conclusion: Endonasal endoscopic control during adenoidectomy helps to identify vascular structures that would normally be at risk of being injured with blind resection. Endoscopic viewing also enables complete removal of intranasal adenoid tissue without significant prolongation in operation time.","PeriodicalId":41744,"journal":{"name":"ENT Updates","volume":null,"pages":null},"PeriodicalIF":0.1,"publicationDate":"2020-11-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46837848","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-11-28DOI: 10.22541/au.160659191.19443051/v1
Sinan Eroğlu, E. Şahin, S. Yoluc, Y. Eroğlu, İ. Aydoğdu
Objective: Novel Coronavirus disease is a new infectious agent of the respiratory tract characterized by a severe acute respiratory syndrome. For this disease, there are limited data with regard to the clinical characteristics of the patients and prognostic factors. Study Design: Retrospective Cohort Setting: Secondary Referral Center Methods: We collected data from 213 patients who were hospitalized into COVID-19 isolation with positive PCR test results. We recorded various patient values, including blood test results. We also noted age, gender, additional diseases, duration of discharge, whether they live or die, whether they smoke, and their radiological staging. Results: In CT imaging with a staging of maximum 4 points and minimum 0 points, the mean value resulted in 1.95. The average radiological stage of the dead patients group was reported as 2.56. There was a correlation between the radiological predictor and the outcome status (p-value: 0.002). The number of smokers was 14 (6.5%). Of the 26 patients who died, 3 were smokers and 23 were non-smokers. Conclusion: 14 of the patients in the study were smokers (6.5%). One in four people in Turkey is a smoker, while in COVID-19 isolation service only a 6.5% rate of smoking was observed. That supports the theory that smoking hasn’t negative impact on COVID-19 development. The average radiological stage was reported as 2.56 in the dead patients’s group. There was a correlation between the radiological predictor and the outcome status (p-value: 0.002). It seems that an elevated radiological stage is a predictor of death. Keywords: Covid-19, SARS-CoV-2, smoking, computed tomography, predictor factors. Key points: to learn relations between smoking and covid-19, effect of Ct stages on the disease severity, effect of blood analysis on Covid-19, the parameters in deaths of Covid-19, ratio of smoking in Covid-19 inpatients
{"title":"Chest image staging and prevalence of current smoking among hospitalized COVID-19 patients in Turkey","authors":"Sinan Eroğlu, E. Şahin, S. Yoluc, Y. Eroğlu, İ. Aydoğdu","doi":"10.22541/au.160659191.19443051/v1","DOIUrl":"https://doi.org/10.22541/au.160659191.19443051/v1","url":null,"abstract":"Objective: Novel Coronavirus disease is a new infectious agent of the\u0000respiratory tract characterized by a severe acute respiratory syndrome.\u0000For this disease, there are limited data with regard to the clinical\u0000characteristics of the patients and prognostic factors. Study Design:\u0000Retrospective Cohort Setting: Secondary Referral Center Methods: We\u0000collected data from 213 patients who were hospitalized into COVID-19\u0000isolation with positive PCR test results. We recorded various patient\u0000values, including blood test results. We also noted age, gender,\u0000additional diseases, duration of discharge, whether they live or die,\u0000whether they smoke, and their radiological staging. Results: In CT\u0000imaging with a staging of maximum 4 points and minimum 0 points, the\u0000mean value resulted in 1.95. The average radiological stage of the dead\u0000patients group was reported as 2.56. There was a correlation between the\u0000radiological predictor and the outcome status (p-value: 0.002). The\u0000number of smokers was 14 (6.5%). Of the 26 patients who died, 3 were\u0000smokers and 23 were non-smokers. Conclusion: 14 of the patients in the\u0000study were smokers (6.5%). One in four people in Turkey is a smoker,\u0000while in COVID-19 isolation service only a 6.5% rate of smoking was\u0000observed. That supports the theory that smoking hasn’t negative impact\u0000on COVID-19 development. The average radiological stage was reported as\u00002.56 in the dead patients’s group. There was a correlation between the\u0000radiological predictor and the outcome status (p-value: 0.002). It seems\u0000that an elevated radiological stage is a predictor of death. Keywords:\u0000Covid-19, SARS-CoV-2, smoking, computed tomography, predictor factors.\u0000Key points: to learn relations between smoking and covid-19, effect of\u0000Ct stages on the disease severity, effect of blood analysis on Covid-19,\u0000the parameters in deaths of Covid-19, ratio of smoking in Covid-19\u0000inpatients","PeriodicalId":41744,"journal":{"name":"ENT Updates","volume":null,"pages":null},"PeriodicalIF":0.1,"publicationDate":"2020-11-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46405920","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-08-25DOI: 10.32448/entupdates.729178
Ayla Uzun Çiçek, Adem Bora, E. Altuntaş
Objective: Adenoid hypertrophy and nocturnal enuresis, comorbidities that are quite prevalent among children, are both associated with sleep problems. However, limited research has specifically focused on sleep domains and their parameters. In the present study we thus aimed to investigate the impact of adenoid hypertrophy and nocturnal enuresis on sleep, both when the two disorders coexist and when they do not coexist. Methods: We investigated 178 children (mean age: 7.24±1.02 years, range=6-9 years), 50 (28.1%) of whom had only adenoid hypertrophy, 39 (21.9%) of whom had only nocturnal enuresis, 35 (19.7%) of whom had coexistence of adenoid hypertrophy and nocturnal enuresis, and 54 (30.3%) of whom were healthy-control children. Psychiatric disorders were diagnosed by a semi-structured diagnosis interview and the diagnosis of adenoid hypertrophy was confirmed by flexible fiberoptic nasopharyngoscopy. Sleep habits and disturbances were assessed via the Children’s Sleep Habits Questionnaire and Modified Epworth Sleepiness Scale. Results: Our results showed that the comorbid condition was the most severe form in terms of both adenoid hypertrophy and enuresis. Regarding sleep difficulties, the "Sleep-Disordered Breathing", "Night Wakings", "Sleep Onset Delay" and "Sleep Duration" parameters were closely associated with adenoid hypertrophy and its severity, while "Bedtime Resistance", "Parasomnias" and "Sleep Anxiety" domains of sleep were strongly related to nocturnal enuresis. Conclusion: Otorhinolaryngologists, child psychiatrists and pediatricians should be aware of the relationship between enuresis and adenoid hypertrophy, that both diseases are associated with impaired sleep patterns, and that children affected by the comorbidity of the two disorders experience more sleep disturbances.
{"title":"Adenoid hypertrophy and nocturnal enuresis are associated with sleep disturbances","authors":"Ayla Uzun Çiçek, Adem Bora, E. Altuntaş","doi":"10.32448/entupdates.729178","DOIUrl":"https://doi.org/10.32448/entupdates.729178","url":null,"abstract":"Objective: Adenoid hypertrophy and nocturnal enuresis, comorbidities that are quite prevalent among children, are both associated with sleep problems. However, limited research has specifically focused on sleep domains and their parameters. In the present study we thus aimed to investigate the impact of adenoid hypertrophy and nocturnal enuresis on sleep, both when the two disorders coexist and when they do not coexist. Methods: We investigated 178 children (mean age: 7.24±1.02 years, range=6-9 years), 50 (28.1%) of whom had only adenoid hypertrophy, 39 (21.9%) of whom had only nocturnal enuresis, 35 (19.7%) of whom had coexistence of adenoid hypertrophy and nocturnal enuresis, and 54 (30.3%) of whom were healthy-control children. Psychiatric disorders were diagnosed by a semi-structured diagnosis interview and the diagnosis of adenoid hypertrophy was confirmed by flexible fiberoptic nasopharyngoscopy. Sleep habits and disturbances were assessed via the Children’s Sleep Habits Questionnaire and Modified Epworth Sleepiness Scale. Results: Our results showed that the comorbid condition was the most severe form in terms of both adenoid hypertrophy and enuresis. Regarding sleep difficulties, the \"Sleep-Disordered Breathing\", \"Night Wakings\", \"Sleep Onset Delay\" and \"Sleep Duration\" parameters were closely associated with adenoid hypertrophy and its severity, while \"Bedtime Resistance\", \"Parasomnias\" and \"Sleep Anxiety\" domains of sleep were strongly related to nocturnal enuresis. Conclusion: Otorhinolaryngologists, child psychiatrists and pediatricians should be aware of the relationship between enuresis and adenoid hypertrophy, that both diseases are associated with impaired sleep patterns, and that children affected by the comorbidity of the two disorders experience more sleep disturbances.","PeriodicalId":41744,"journal":{"name":"ENT Updates","volume":null,"pages":null},"PeriodicalIF":0.1,"publicationDate":"2020-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46287939","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-04-25DOI: 10.32448/entupdates.696940
E. Erdiş, B. Yücel
Introduction: In the present study, we aimed to evaluate the relationship between neutrophil/lymphocyte ratio (NLR), platelet/lymphocyte ratio (PLR) and systemic immune inflammation index (SII) values and overall survival (OS) and disease-free survival (DFS) in patients undergoing radiotherapy with a diagnosis of oral cavity cancer (OCC). Methods: 58 patients were included who were treated with a diagnosis of OCC who applied to Cumhuriyet University Faculty of Medicine Radiation Oncology Clinic between January 2009 and December 2018. Kaplan-Meier analysis was used to determine OS and DFS. Multivariate Cox regression analysis was also performed to detect independent prognostic factors. Results: All patients had a squamous cell carcinoma (SCC) of the oral cavity composed of 50 tongue SCC and 8 buccal SCC. Cut-off values in ROC analysis: 954 [Area=0.665 (0.511-0.800), p=0.06] for SII, 174 [Area=0.659 (0.608-0.795), p<.001] for PLR and 3.2 [Area=0.699 (0.556-0.841), p=0.016] for NLR. Prognostic factors affecting OS were SII, PLR, NLR and age. SII, NLR, PLR and grade were statistically significant prognostic factors for DFS. However, SII was an independent prognostic factor. Conclusion: In this study, high SII value was found to be an indicator of shorter OS and DFS in patients with OCC.
{"title":"Prognostic Significance of Inflammatory Markers in Patients with Oral Cavity Tumors","authors":"E. Erdiş, B. Yücel","doi":"10.32448/entupdates.696940","DOIUrl":"https://doi.org/10.32448/entupdates.696940","url":null,"abstract":"Introduction: In the present study, we aimed to evaluate the relationship between neutrophil/lymphocyte ratio (NLR), platelet/lymphocyte ratio (PLR) and systemic immune inflammation index (SII) values and overall survival (OS) and disease-free survival (DFS) in patients undergoing radiotherapy with a diagnosis of oral cavity cancer (OCC). Methods: 58 patients were included who were treated with a diagnosis of OCC who applied to Cumhuriyet University Faculty of Medicine Radiation Oncology Clinic between January 2009 and December 2018. Kaplan-Meier analysis was used to determine OS and DFS. Multivariate Cox regression analysis was also performed to detect independent prognostic factors. Results: All patients had a squamous cell carcinoma (SCC) of the oral cavity composed of 50 tongue SCC and 8 buccal SCC. Cut-off values in ROC analysis: 954 [Area=0.665 (0.511-0.800), p=0.06] for SII, 174 [Area=0.659 (0.608-0.795), p<.001] for PLR and 3.2 [Area=0.699 (0.556-0.841), p=0.016] for NLR. Prognostic factors affecting OS were SII, PLR, NLR and age. SII, NLR, PLR and grade were statistically significant prognostic factors for DFS. However, SII was an independent prognostic factor. Conclusion: In this study, high SII value was found to be an indicator of shorter OS and DFS in patients with OCC.","PeriodicalId":41744,"journal":{"name":"ENT Updates","volume":null,"pages":null},"PeriodicalIF":0.1,"publicationDate":"2020-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42613408","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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