Pub Date : 2022-12-01DOI: 10.4274/jus.galenos.2022.2022.0002
Günal Özgür, M. Çetin, T. Telli, D. Filinte, I. Tinay
We report on a patient, who was diagnosed with renal cell carcinoma (RCC) and presented with testicular metastasis at 5 years after the initial diagnosis, surgical interventions and systemic treatments. Although there are reports of testicular metastasis of RCC, to the best of our knowledge, our case is first who presented late recurrence in the testicular tissue despite previous tyrosine kinase inhibitor and PD1 inhibitor treatments.
{"title":"Testicular Metastasis in Renal Cell Carcinoma","authors":"Günal Özgür, M. Çetin, T. Telli, D. Filinte, I. Tinay","doi":"10.4274/jus.galenos.2022.2022.0002","DOIUrl":"https://doi.org/10.4274/jus.galenos.2022.2022.0002","url":null,"abstract":"We report on a patient, who was diagnosed with renal cell carcinoma (RCC) and presented with testicular metastasis at 5 years after the initial diagnosis, surgical interventions and systemic treatments. Although there are reports of testicular metastasis of RCC, to the best of our knowledge, our case is first who presented late recurrence in the testicular tissue despite previous tyrosine kinase inhibitor and PD1 inhibitor treatments.","PeriodicalId":42050,"journal":{"name":"Journal of Urological Surgery","volume":" ","pages":""},"PeriodicalIF":0.3,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43951311","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-12-01DOI: 10.4274/jus.galenos.2022.2022.0014
K. Mehra, Neeraj Agarwal, R. Manikandan
In developing countries, where the availability of expensive instruments like flexible cystoscopes may not be available everywhere, the semirigid ureteroscopes can be as comfortable as flexible cystoscopes for both patients and surgeons. The study findings can lead to
{"title":"Outcomes of Ureteral Stent Removal by Flexible Cystoscope Versus Semirigid Ureteroscope: A Prospective Randomized Clinical Trial","authors":"K. Mehra, Neeraj Agarwal, R. Manikandan","doi":"10.4274/jus.galenos.2022.2022.0014","DOIUrl":"https://doi.org/10.4274/jus.galenos.2022.2022.0014","url":null,"abstract":"In developing countries, where the availability of expensive instruments like flexible cystoscopes may not be available everywhere, the semirigid ureteroscopes can be as comfortable as flexible cystoscopes for both patients and surgeons. The study findings can lead to","PeriodicalId":42050,"journal":{"name":"Journal of Urological Surgery","volume":" ","pages":""},"PeriodicalIF":0.3,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44563733","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-12-01DOI: 10.4274/jus.galenos.2022.2022.0012
K. Gasimov, R. Jafarov, V. Tatanis, A. Bozacı, E. Ceyhan, Turan Mammadaliyev, H. Doğan, S. Tekgül
Despite having different etiologies
尽管病因不同
{"title":"Children with Non-Neurogenic Lower Urinary Tract Dysfunction Require Less Frequent and Number of Botulinum Toxin Injections Than Neurogenic Ones","authors":"K. Gasimov, R. Jafarov, V. Tatanis, A. Bozacı, E. Ceyhan, Turan Mammadaliyev, H. Doğan, S. Tekgül","doi":"10.4274/jus.galenos.2022.2022.0012","DOIUrl":"https://doi.org/10.4274/jus.galenos.2022.2022.0012","url":null,"abstract":"Despite having different etiologies","PeriodicalId":42050,"journal":{"name":"Journal of Urological Surgery","volume":" ","pages":""},"PeriodicalIF":0.3,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48686591","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-12-01DOI: 10.4274/jus.galenos.2022.2021.0126
Mert Hamza Özbilen, Erdem Kısa, A. Çapar, Y. Ilbey
was performed
已执行
{"title":"Life-threatening Arterioureteral Fistula Between Iliac Vessel and Ureteral Stump: A Case Report","authors":"Mert Hamza Özbilen, Erdem Kısa, A. Çapar, Y. Ilbey","doi":"10.4274/jus.galenos.2022.2021.0126","DOIUrl":"https://doi.org/10.4274/jus.galenos.2022.2021.0126","url":null,"abstract":"was performed","PeriodicalId":42050,"journal":{"name":"Journal of Urological Surgery","volume":" ","pages":""},"PeriodicalIF":0.3,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48932220","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-09-14DOI: 10.4274/jus.galenos.2022.2021.0099
O. Üçer, G. Temeltaş, T. Müezzinoğlu, Z. Arı, F. Kosova
In this study, we found that in non-muscle invasive bladder cancer cases, transurethral resection of bladder tumor decreased the tumor weight and accordingly, cytokine levels decreased. Abstract Objective: The present study investigated the effect of treatment on interleukin (IL)-1, IL-6, IL-8, and neopterin levels in patients with non-muscle invasive bladder cancer (NMIBC). Materials and Methods: Thirty patients with NMIBC and 30 age-matched controls were included in the study. Preoperative, postoperative first control [at two weeks after second transurethral resection of bladder tumor (TURBT)] and the second control (at the end of intravesical immunotherapy) blood samples were analyzed using ELISA to determine IL-1, IL-6, IL-8, and neopterin levels. The mean cytokine levels of the patients were statistically compared and comparing the patients’ and controls’ levels. Results: There were no statistically significant differences between the mean IL-1, IL-6, IL-8, and neopterin levels of the patient and control groups before initial TURBT. In the patient group, there were no statistically significant differences in the IL-6 and IL-8 levels after both TURBT and intravesical Bacillus Calmette-Guérin (BCG) therapy. The mean of preoperative IL-1 and neopterin levels significantly decreased after TURBT (p<0.05). However, this reduction does not continue after intravesical BCG instillation. Conclusion: The findings of this study showed that the IL-1, IL-6, IL-8, and neopterin levels of the patients with NMIBC were similar to the levels of healthy controls. IL-1 and neopterin levels significantly decreased after TURBT. But these reduction did not continue after intravesical BCG instillation. These findings demonstrate that IL-1 and neopterin levels decrease after TURBT due to the reduction in tumor weight or tumor removal.
{"title":"The Effect of Transurethral Resection and BCG Therapy on Cytokine Levels in Non-Muscle Invasive Bladder Cancer","authors":"O. Üçer, G. Temeltaş, T. Müezzinoğlu, Z. Arı, F. Kosova","doi":"10.4274/jus.galenos.2022.2021.0099","DOIUrl":"https://doi.org/10.4274/jus.galenos.2022.2021.0099","url":null,"abstract":"In this study, we found that in non-muscle invasive bladder cancer cases, transurethral resection of bladder tumor decreased the tumor weight and accordingly, cytokine levels decreased. Abstract Objective: The present study investigated the effect of treatment on interleukin (IL)-1, IL-6, IL-8, and neopterin levels in patients with non-muscle invasive bladder cancer (NMIBC). Materials and Methods: Thirty patients with NMIBC and 30 age-matched controls were included in the study. Preoperative, postoperative first control [at two weeks after second transurethral resection of bladder tumor (TURBT)] and the second control (at the end of intravesical immunotherapy) blood samples were analyzed using ELISA to determine IL-1, IL-6, IL-8, and neopterin levels. The mean cytokine levels of the patients were statistically compared and comparing the patients’ and controls’ levels. Results: There were no statistically significant differences between the mean IL-1, IL-6, IL-8, and neopterin levels of the patient and control groups before initial TURBT. In the patient group, there were no statistically significant differences in the IL-6 and IL-8 levels after both TURBT and intravesical Bacillus Calmette-Guérin (BCG) therapy. The mean of preoperative IL-1 and neopterin levels significantly decreased after TURBT (p<0.05). However, this reduction does not continue after intravesical BCG instillation. Conclusion: The findings of this study showed that the IL-1, IL-6, IL-8, and neopterin levels of the patients with NMIBC were similar to the levels of healthy controls. IL-1 and neopterin levels significantly decreased after TURBT. But these reduction did not continue after intravesical BCG instillation. These findings demonstrate that IL-1 and neopterin levels decrease after TURBT due to the reduction in tumor weight or tumor removal.","PeriodicalId":42050,"journal":{"name":"Journal of Urological Surgery","volume":" ","pages":""},"PeriodicalIF":0.3,"publicationDate":"2022-09-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42898688","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-09-14DOI: 10.4274/jus.galenos.2021.2021.0098
S. Madendere, Görkem Türkkan, E. Arda, Vuslat Yürüt Çaloğlu, U. Kuyumcuoglu
According to previous studies, preoperative and postoperative prostate specific antigen level measurements, pathological stage, Gleason score, extraprostatic extension, positive surgical margins and seminal vesicle invasion could be the predictors of biochemical progression and biochemical progression-free survival in prostate cancer patients undergoing radical prostatectomy. In our study, we showed that postoperative prostate specific antigen level higher than ≥0.2 ng/dL is the most important predictor of biochemical progression and biochemical progression-free survival in prostate cancer patients undergoing radical prostatectomy. Abstract Objective: The aim of this study was to investigate the potential relationship between biochemical progression and prognostic risk factors in patients with prostate cancer (PCa) patients undergoing radical prostatectomy (RP). Materials and Methods: After inclusion/exclusion criteria were applied, 216 patients who underwent RP were included in this study. Follow-up protocol included prostate specific antigen (PSA) measurements; every 3 months for the first year, every 6 months for the second year, and an annual check after 2 years. Preoperative and postoperative PSA measurements, pathological stage, Gleason score (GS), extraprostatic extension, positive surgical margins and seminal vesicle invasion were evaluated. Uni- and multivariable analyses were used to detect the relationship between biochemical progression, biochemical progression-free survival (BPFS) and prognostic risk factors. Results: Median follow-up was 29 months. Biochemical progression was observed in 39 (18.1%) patients, in 18 (9.7%) of 185 patients with first postoperative PSA level of <0.2 ng/dL, and 21 (67.7%) of 31 patients with first postoperative PSA level of ≥0.2 ng/dL. Patients with first postoperative PSA level of ≥0.2 ng/dL had a statistically significant higher risk of biochemical progression and shorter BPFS (odds ratio: 2.41; 95% confidence interval: 1.84-3.10; p<0.001), in univariate and multivariate analyses. Patients with GS ≥8 or T3-4 or positive surgical margins had a statistically significant higher risk of biochemical progression (p<0.001, p=0.003, p<0.001). Conclusion: Postoperative PSA level higher than ≥0.2 ng/dL was the most important predictor of biochemical progression and BPFS after RP. GS ≥8, T3-4 stages, and positive surgical margins are also related to biochemical progression.
{"title":"Evaluation of Risk Groups for the Prediction of Biochemical Progression in Patients Undergoing Radical Prostatectomy","authors":"S. Madendere, Görkem Türkkan, E. Arda, Vuslat Yürüt Çaloğlu, U. Kuyumcuoglu","doi":"10.4274/jus.galenos.2021.2021.0098","DOIUrl":"https://doi.org/10.4274/jus.galenos.2021.2021.0098","url":null,"abstract":"According to previous studies, preoperative and postoperative prostate specific antigen level measurements, pathological stage, Gleason score, extraprostatic extension, positive surgical margins and seminal vesicle invasion could be the predictors of biochemical progression and biochemical progression-free survival in prostate cancer patients undergoing radical prostatectomy. In our study, we showed that postoperative prostate specific antigen level higher than ≥0.2 ng/dL is the most important predictor of biochemical progression and biochemical progression-free survival in prostate cancer patients undergoing radical prostatectomy. Abstract Objective: The aim of this study was to investigate the potential relationship between biochemical progression and prognostic risk factors in patients with prostate cancer (PCa) patients undergoing radical prostatectomy (RP). Materials and Methods: After inclusion/exclusion criteria were applied, 216 patients who underwent RP were included in this study. Follow-up protocol included prostate specific antigen (PSA) measurements; every 3 months for the first year, every 6 months for the second year, and an annual check after 2 years. Preoperative and postoperative PSA measurements, pathological stage, Gleason score (GS), extraprostatic extension, positive surgical margins and seminal vesicle invasion were evaluated. Uni- and multivariable analyses were used to detect the relationship between biochemical progression, biochemical progression-free survival (BPFS) and prognostic risk factors. Results: Median follow-up was 29 months. Biochemical progression was observed in 39 (18.1%) patients, in 18 (9.7%) of 185 patients with first postoperative PSA level of <0.2 ng/dL, and 21 (67.7%) of 31 patients with first postoperative PSA level of ≥0.2 ng/dL. Patients with first postoperative PSA level of ≥0.2 ng/dL had a statistically significant higher risk of biochemical progression and shorter BPFS (odds ratio: 2.41; 95% confidence interval: 1.84-3.10; p<0.001), in univariate and multivariate analyses. Patients with GS ≥8 or T3-4 or positive surgical margins had a statistically significant higher risk of biochemical progression (p<0.001, p=0.003, p<0.001). Conclusion: Postoperative PSA level higher than ≥0.2 ng/dL was the most important predictor of biochemical progression and BPFS after RP. GS ≥8, T3-4 stages, and positive surgical margins are also related to biochemical progression.","PeriodicalId":42050,"journal":{"name":"Journal of Urological Surgery","volume":" ","pages":""},"PeriodicalIF":0.3,"publicationDate":"2022-09-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46592128","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-09-14DOI: 10.4274/jus.galenos.2022.2021.0106
Farajollah Parhoudeh, Niloofar Hemati, T. Najafi, A. Ahmadi, R. Mohammadi
Numerous reports have indicated a foreign body in the bladder. Various objects, or more precisely, everything in the human environment, have been found in the urinary bladder. In the current case study, the patient was a single 38-year-old woman who was referred to the emergency department with the complaints of lower urinary tract symptoms. The patient’s history and radiological examination confirmed the presence of a foreign body (mobile phone charger cable) in the bladder. Since the patient was not mentally retarded and had no history of substance abuse, investigating other mental disorders and sexual abuse for her was recommended.
{"title":"Mobile Charger Cable in Urinary Bladder of a Patient with No History of Mental Disorder","authors":"Farajollah Parhoudeh, Niloofar Hemati, T. Najafi, A. Ahmadi, R. Mohammadi","doi":"10.4274/jus.galenos.2022.2021.0106","DOIUrl":"https://doi.org/10.4274/jus.galenos.2022.2021.0106","url":null,"abstract":"Numerous reports have indicated a foreign body in the bladder. Various objects, or more precisely, everything in the human environment, have been found in the urinary bladder. In the current case study, the patient was a single 38-year-old woman who was referred to the emergency department with the complaints of lower urinary tract symptoms. The patient’s history and radiological examination confirmed the presence of a foreign body (mobile phone charger cable) in the bladder. Since the patient was not mentally retarded and had no history of substance abuse, investigating other mental disorders and sexual abuse for her was recommended.","PeriodicalId":42050,"journal":{"name":"Journal of Urological Surgery","volume":" ","pages":""},"PeriodicalIF":0.3,"publicationDate":"2022-09-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46349518","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-09-14DOI: 10.4274/jus.galenos.2022.2021.0109
Tunkut Doğanca, M. Tuna, Y. Sağlıcan, A. Kural
Signet-ring cell carcinoma of the bladder is very rare pathology and can be seen as a primary disease or a metastatic manifestation. In this case report, we present the metastasis of gastric signet-ring cell carcinoma to the bladder, which was detected incidentally during follow-up of a 45-years-old male patient who had previous Ta low-grade urothelial cell carcinoma diagnosis.
{"title":"Metastasis of Gastric Signet-Ring Cell Carcinoma to the Bladder: An Incidental Finding During Cystoscopy","authors":"Tunkut Doğanca, M. Tuna, Y. Sağlıcan, A. Kural","doi":"10.4274/jus.galenos.2022.2021.0109","DOIUrl":"https://doi.org/10.4274/jus.galenos.2022.2021.0109","url":null,"abstract":"Signet-ring cell carcinoma of the bladder is very rare pathology and can be seen as a primary disease or a metastatic manifestation. In this case report, we present the metastasis of gastric signet-ring cell carcinoma to the bladder, which was detected incidentally during follow-up of a 45-years-old male patient who had previous Ta low-grade urothelial cell carcinoma diagnosis.","PeriodicalId":42050,"journal":{"name":"Journal of Urological Surgery","volume":" ","pages":""},"PeriodicalIF":0.3,"publicationDate":"2022-09-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49623439","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-09-14DOI: 10.4274/jus.galenos.2022.2021.0124
I. Seo, T. H. Oh
We present a rare case of the clip migration after laparoscopic partial nephrectomy in which the clips were misdiagnosed as urinary stones. A 57-years-old female presented with right flank pain 3 months after the surgery. A computed tomography scan showed a 4 mm stone in the left upper ureter and hydronephrosis. Another 3 mm stone was also detected in the left upper calyx. Rigid ureteroscopy and flexible ureterorenoscopy revealed two LAPRA-TY clips, which were embedded in the upper ureter and calyx. The clips were fragmented by holmium laser lithotripsy and removed with stone basket. Pain and hydronephrosis are resolved at follow-up.
{"title":"Migration of LAPRA-TY Clips in Ureter and Collecting System Mimicking Urinary Stones Following Laparoscopic Partial Nephrectomy","authors":"I. Seo, T. H. Oh","doi":"10.4274/jus.galenos.2022.2021.0124","DOIUrl":"https://doi.org/10.4274/jus.galenos.2022.2021.0124","url":null,"abstract":"We present a rare case of the clip migration after laparoscopic partial nephrectomy in which the clips were misdiagnosed as urinary stones. A 57-years-old female presented with right flank pain 3 months after the surgery. A computed tomography scan showed a 4 mm stone in the left upper ureter and hydronephrosis. Another 3 mm stone was also detected in the left upper calyx. Rigid ureteroscopy and flexible ureterorenoscopy revealed two LAPRA-TY clips, which were embedded in the upper ureter and calyx. The clips were fragmented by holmium laser lithotripsy and removed with stone basket. Pain and hydronephrosis are resolved at follow-up.","PeriodicalId":42050,"journal":{"name":"Journal of Urological Surgery","volume":" ","pages":""},"PeriodicalIF":0.3,"publicationDate":"2022-09-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42391328","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-09-14DOI: 10.4274/jus.galenos.2022.2021.0131
Abdullah Gürel, B. Baylan, I. Keles, A. Demirbaş, Mustafa Karalar, O. Gerçek, Ünal Öztekin, A. Özen, I. Ulus, Salih Zeki Sönmez, E. Erşekerci, A. Çift, A. Doğan, Berk Yasin Ekenci, C. Bayraktar, M. Karadağ
Objective: The coronavirus disease-2019 (COVID-19) pandemic effect diagnosis and treatment of certain conditions, including bladder cancer (BC). This study aimed to evaluate the effects of the COVID-19 pandemic on BC diagnosis and treatment. Materials and Methods: Following the approval of the ethics committee for the study, data of 869 patients who underwent surgery for BC in the 2-year period between March 1, 2019 and February 28, 2021 were analyzed retrospectively. The number of surgeries performed for BC, the time elapsed between symptoms and diagnosis, the treatments performed, and the operative pathologies were compared before and during the COVID-19 pandemic. Results: During the COVID-19 period, there was a decrease in the total number of BC surgeries compared to the pre-COVID-19 period (p=0.004). It was observed that this decrease was due to a decrease in patients newly diagnosed with BC (p=0.001) as well as the decrease in the number of primary transurethral resection for bladder tumor procedures performed. There was no difference in the tumor stages of the patients at diagnosis (p=0.9). Intracavitary Bacillus Calmette-Guérin therapy use in high-risk non-muscle invasive bladder cancers (NMIBC) patients also decreased (p=0.008) during the pandemic period. It was observed that the time between symptom and diagnosis was longer in MIBC than in NIMBC during both periods (p<0.001). Conclusion: Diagnosis and treatment of BC have been adversely affected by the ongoing COVID-19 pandemic. The decrease in the number of new diagnoses may not reflect a true decrease in BC incidence, meaning that BC cases that arose during the pandemic are likely to be diagnosed at a more advanced stage.
{"title":"Effects of the COVID-19 Pandemic on Bladder Cancer Diagnosis and Treatment Processes; A Turkish Multicenter Study","authors":"Abdullah Gürel, B. Baylan, I. Keles, A. Demirbaş, Mustafa Karalar, O. Gerçek, Ünal Öztekin, A. Özen, I. Ulus, Salih Zeki Sönmez, E. Erşekerci, A. Çift, A. Doğan, Berk Yasin Ekenci, C. Bayraktar, M. Karadağ","doi":"10.4274/jus.galenos.2022.2021.0131","DOIUrl":"https://doi.org/10.4274/jus.galenos.2022.2021.0131","url":null,"abstract":"Objective: The coronavirus disease-2019 (COVID-19) pandemic effect diagnosis and treatment of certain conditions, including bladder cancer (BC). This study aimed to evaluate the effects of the COVID-19 pandemic on BC diagnosis and treatment. Materials and Methods: Following the approval of the ethics committee for the study, data of 869 patients who underwent surgery for BC in the 2-year period between March 1, 2019 and February 28, 2021 were analyzed retrospectively. The number of surgeries performed for BC, the time elapsed between symptoms and diagnosis, the treatments performed, and the operative pathologies were compared before and during the COVID-19 pandemic. Results: During the COVID-19 period, there was a decrease in the total number of BC surgeries compared to the pre-COVID-19 period (p=0.004). It was observed that this decrease was due to a decrease in patients newly diagnosed with BC (p=0.001) as well as the decrease in the number of primary transurethral resection for bladder tumor procedures performed. There was no difference in the tumor stages of the patients at diagnosis (p=0.9). Intracavitary Bacillus Calmette-Guérin therapy use in high-risk non-muscle invasive bladder cancers (NMIBC) patients also decreased (p=0.008) during the pandemic period. It was observed that the time between symptom and diagnosis was longer in MIBC than in NIMBC during both periods (p<0.001). Conclusion: Diagnosis and treatment of BC have been adversely affected by the ongoing COVID-19 pandemic. The decrease in the number of new diagnoses may not reflect a true decrease in BC incidence, meaning that BC cases that arose during the pandemic are likely to be diagnosed at a more advanced stage.","PeriodicalId":42050,"journal":{"name":"Journal of Urological Surgery","volume":" ","pages":""},"PeriodicalIF":0.3,"publicationDate":"2022-09-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49008025","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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