Didem Ayyıldız, N. Perdahlı Fiş, Funda Gümüştaş, D. Seckin
Objective: The aim of this study was to examine comorbid psychiatric disorders, family functioning, and parental psychiatric symptoms in children and adolescents with chronic dermatological diseases and compare them with those of healthy controls. Materials and Methods: The research sample consisted of patients between the age of 9 and 18 years (n = 45) with alopecia areata, vitiligo, or psoriasis and a control group (CG) of healthy children and adolescents of the same age (n = 42). The psychiatric diagnoses of cases were established using Schedule for Affective Disorders and Schizophrenia for School Aged Children Present-Lifetime Version. Family assessment device (FAD) was used to evaluate family functioning levels. Parental psychiatric symptom levels were obtained by the Symptom Checklist-90-R. Results: Children and adolescents with chronic dermatological diseases had significantly higher rates of any anxiety disorders and any axis I comorbid psychiatric disorders than healthy controls after adjusting for socioeconomic status (P < 0.05). There were no significant differences in parental psychiatric symptom levels and family functioning levels between two groups; however, families of patients with comorbid psychiatric disorders had significantly higher scores in problem-solving and communication subscales of the FAD when compared to those of patients without psychiatric disorders and CG. Conclusions: Our findings suggest that children and adolescents with chronic dermatological diseases have higher risk for anxiety disorders. When psychiatric disorders co-occur with the dermatological disease in children and adolescents, they may adversely affect the family functioning, in the domains of problem-solving and communication skills.
{"title":"Psychiatric disorders, family functions, and parent psychiatric symptoms in children and adolescents with chronic dermatological diseases treated with phototherapy","authors":"Didem Ayyıldız, N. Perdahlı Fiş, Funda Gümüştaş, D. Seckin","doi":"10.4103/tjd.tjd_124_20","DOIUrl":"https://doi.org/10.4103/tjd.tjd_124_20","url":null,"abstract":"Objective: The aim of this study was to examine comorbid psychiatric disorders, family functioning, and parental psychiatric symptoms in children and adolescents with chronic dermatological diseases and compare them with those of healthy controls. Materials and Methods: The research sample consisted of patients between the age of 9 and 18 years (n = 45) with alopecia areata, vitiligo, or psoriasis and a control group (CG) of healthy children and adolescents of the same age (n = 42). The psychiatric diagnoses of cases were established using Schedule for Affective Disorders and Schizophrenia for School Aged Children Present-Lifetime Version. Family assessment device (FAD) was used to evaluate family functioning levels. Parental psychiatric symptom levels were obtained by the Symptom Checklist-90-R. Results: Children and adolescents with chronic dermatological diseases had significantly higher rates of any anxiety disorders and any axis I comorbid psychiatric disorders than healthy controls after adjusting for socioeconomic status (P < 0.05). There were no significant differences in parental psychiatric symptom levels and family functioning levels between two groups; however, families of patients with comorbid psychiatric disorders had significantly higher scores in problem-solving and communication subscales of the FAD when compared to those of patients without psychiatric disorders and CG. Conclusions: Our findings suggest that children and adolescents with chronic dermatological diseases have higher risk for anxiety disorders. When psychiatric disorders co-occur with the dermatological disease in children and adolescents, they may adversely affect the family functioning, in the domains of problem-solving and communication skills.","PeriodicalId":42454,"journal":{"name":"Turk Dermatoloji Dergisi-Turkish Journal of Dermatology","volume":"22 1","pages":"28 - 33"},"PeriodicalIF":0.1,"publicationDate":"2021-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76987186","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Skin cancer is the most common type of cancer. Nonmelanoma skin cancers (NMSCs) are more common than malignant melanoma. It is expected that the incidence of skin cancer will increase in the future. Although the mortality rate is low, cancer wording can be frightening for patients. Because skin cancers are most commonly located in the head and neck, unwanted cosmetic consequences can occur as a result of treatments. Therefore, the quality of life (QOL) of patients could be affected negatively. Today, there are various scales that assess the QOL of patients. These can be grouped as general, disease-specific, and cancer-specific questionnaires. Studies have been carried out and are still in progress to develop scales of QOL specific to skin cancers. In this paper, the questionnaires used in malignant melanoma and/or NMSCs and studies on this subject are reviewed.
{"title":"An update on quality of life in malignant melanoma and nonmelanoma skin cancers","authors":"T. Çetinarslan, M. Evrenos, A. Ermertcan","doi":"10.4103/tjd.tjd_16_21","DOIUrl":"https://doi.org/10.4103/tjd.tjd_16_21","url":null,"abstract":"Skin cancer is the most common type of cancer. Nonmelanoma skin cancers (NMSCs) are more common than malignant melanoma. It is expected that the incidence of skin cancer will increase in the future. Although the mortality rate is low, cancer wording can be frightening for patients. Because skin cancers are most commonly located in the head and neck, unwanted cosmetic consequences can occur as a result of treatments. Therefore, the quality of life (QOL) of patients could be affected negatively. Today, there are various scales that assess the QOL of patients. These can be grouped as general, disease-specific, and cancer-specific questionnaires. Studies have been carried out and are still in progress to develop scales of QOL specific to skin cancers. In this paper, the questionnaires used in malignant melanoma and/or NMSCs and studies on this subject are reviewed.","PeriodicalId":42454,"journal":{"name":"Turk Dermatoloji Dergisi-Turkish Journal of Dermatology","volume":"51 1","pages":"17 - 27"},"PeriodicalIF":0.1,"publicationDate":"2021-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78228206","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: Acne vulgaris is a common cutaneous condition seen globally and has a considerable psychosocial impact. Many patients with acne try various forms of self-medication, alternative therapies, and prescription medicines for the treatment of acne. Methods: We studied various patterns of acne treatments used in a cross-sectional study among patients presenting in a tertiary care hospital. A 2-part questionnaire was used to evaluate the socio-epidemiologic factors and responses to treatments used by acne patients presenting at our center for the first time. The patients used self-medication, alternative therapies (e.g., Ayurveda), treatments from general practitioners, and also specialists. Results: Most of the patients reported either no treatment response or even deterioration. Several patients even used topical steroids and suffered adverse effects (corticosteroid-induced rosacea-like facial dermatitis). Conclusion: The findings of our study stress the role of appropriate counseling of acne patients in management. Improvement in the doctor-patient relationship is also essential to enhance the treatment efficacy in acne.
{"title":"The pattern of medication used by acne patients: Study from a tertiary care center of North India","authors":"N. Kansal, N. Hazarika","doi":"10.4103/tjd.tjd_35_21","DOIUrl":"https://doi.org/10.4103/tjd.tjd_35_21","url":null,"abstract":"Background: Acne vulgaris is a common cutaneous condition seen globally and has a considerable psychosocial impact. Many patients with acne try various forms of self-medication, alternative therapies, and prescription medicines for the treatment of acne. Methods: We studied various patterns of acne treatments used in a cross-sectional study among patients presenting in a tertiary care hospital. A 2-part questionnaire was used to evaluate the socio-epidemiologic factors and responses to treatments used by acne patients presenting at our center for the first time. The patients used self-medication, alternative therapies (e.g., Ayurveda), treatments from general practitioners, and also specialists. Results: Most of the patients reported either no treatment response or even deterioration. Several patients even used topical steroids and suffered adverse effects (corticosteroid-induced rosacea-like facial dermatitis). Conclusion: The findings of our study stress the role of appropriate counseling of acne patients in management. Improvement in the doctor-patient relationship is also essential to enhance the treatment efficacy in acne.","PeriodicalId":42454,"journal":{"name":"Turk Dermatoloji Dergisi-Turkish Journal of Dermatology","volume":"93 1","pages":"40 - 43"},"PeriodicalIF":0.1,"publicationDate":"2021-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79437973","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objectives: To investigate the behavioral characteristics of infants with diaper dermatitis as well as the habits of their caregivers and the effects of those habits on infants with diaper dermatitis. Methods: The participants' demographic features, the infants' behavior, and the caregivers' habits were evaluated using a questionnaire. The severity of diaper dermatitis was scored using the Cincinnati Children's Hospital Diaper Dermatitis Grading Scale. Results: A statistically significant difference in terms of the infants' behavioral changes was found in relation to the different maternal education level groups (P < 0.001). Three well-known discomfort behaviors, namely easy crying, changes in eating habits, and changes in sleeping patterns, were observed in infants with diaper dermatitis who were being raised by uneducated caregivers. Conclusions: The growth and development of babies with recurrent diaper dermatitis may be affected over time if adequate protection methods are not applied to prevent diaper dermatitis. Both diaper dermatitis and recurrent attacks can be prevented by adequate training of the caregivers of babies prone to diaper dermatitis. Babies who are not restless and whose sleeping and eating patterns are not disturbed may develop healthier growth.
{"title":"The severity of diaper dermatitis and the effects of caregivers' habits on infants' behaviors","authors":"Vildan Manav","doi":"10.4103/tjd.tjd_17_21","DOIUrl":"https://doi.org/10.4103/tjd.tjd_17_21","url":null,"abstract":"Objectives: To investigate the behavioral characteristics of infants with diaper dermatitis as well as the habits of their caregivers and the effects of those habits on infants with diaper dermatitis. Methods: The participants' demographic features, the infants' behavior, and the caregivers' habits were evaluated using a questionnaire. The severity of diaper dermatitis was scored using the Cincinnati Children's Hospital Diaper Dermatitis Grading Scale. Results: A statistically significant difference in terms of the infants' behavioral changes was found in relation to the different maternal education level groups (P < 0.001). Three well-known discomfort behaviors, namely easy crying, changes in eating habits, and changes in sleeping patterns, were observed in infants with diaper dermatitis who were being raised by uneducated caregivers. Conclusions: The growth and development of babies with recurrent diaper dermatitis may be affected over time if adequate protection methods are not applied to prevent diaper dermatitis. Both diaper dermatitis and recurrent attacks can be prevented by adequate training of the caregivers of babies prone to diaper dermatitis. Babies who are not restless and whose sleeping and eating patterns are not disturbed may develop healthier growth.","PeriodicalId":42454,"journal":{"name":"Turk Dermatoloji Dergisi-Turkish Journal of Dermatology","volume":"15 1","pages":"34 - 39"},"PeriodicalIF":0.1,"publicationDate":"2021-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72717748","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: Striae distensae (SD) are visible linear scars in areas of dermal damage due to excessive stretching of the skin. Striae can cause cosmetic morbidity and psychological distress, particularly in women. In spite of several advances, no definitive treatment has emerged. Aim: The aim of this study was to evaluate the efficacy of microneedling versus cryoroller liquid nitrogen therapy in the management of striae distensae both clinically and histopathologically. Methodology: Striae of all 27 patients were treated with needling and cryoroller liquid nitrogen therapy on two different sides of each patient. Digital photography and skin biopsy were done to assess clinical and histopathological improvement. Results: On the evaluation of clinical response, poor clinical response (≤2%) was seen in 92.6% (n = 25) of patients on the dermaroller side, followed by moderate clinical response and on the cryoroller side, poor clinical response was seen in all 27 patients. Comparing the two sides, on the dermaroller side, 77.8% (n = 21) were satisfied and on the cryoroller side, 55.6% (n = 15) of the patients were slightly satisfied and 29.6% (n = 8) were satisfied. The histopathological improvement was almost similar on both dermaroller and cryoroller sides. Conclusion: Both microneedling with dermaroller and liquid nitrogen cryoroller were found to be safe and partially effective methods to treat striae. Patients were more satisfied with microneedling than cryoroller.
{"title":"A clinical and histopathological study comparing efficacy of microneedling versus cryoroller liquid nitrogen therapy in the treatment of striae distensae","authors":"Vrushali Salve, H. Pathave, C. Nayak","doi":"10.4103/tjd.tjd_12_21","DOIUrl":"https://doi.org/10.4103/tjd.tjd_12_21","url":null,"abstract":"Background: Striae distensae (SD) are visible linear scars in areas of dermal damage due to excessive stretching of the skin. Striae can cause cosmetic morbidity and psychological distress, particularly in women. In spite of several advances, no definitive treatment has emerged. Aim: The aim of this study was to evaluate the efficacy of microneedling versus cryoroller liquid nitrogen therapy in the management of striae distensae both clinically and histopathologically. Methodology: Striae of all 27 patients were treated with needling and cryoroller liquid nitrogen therapy on two different sides of each patient. Digital photography and skin biopsy were done to assess clinical and histopathological improvement. Results: On the evaluation of clinical response, poor clinical response (≤2%) was seen in 92.6% (n = 25) of patients on the dermaroller side, followed by moderate clinical response and on the cryoroller side, poor clinical response was seen in all 27 patients. Comparing the two sides, on the dermaroller side, 77.8% (n = 21) were satisfied and on the cryoroller side, 55.6% (n = 15) of the patients were slightly satisfied and 29.6% (n = 8) were satisfied. The histopathological improvement was almost similar on both dermaroller and cryoroller sides. Conclusion: Both microneedling with dermaroller and liquid nitrogen cryoroller were found to be safe and partially effective methods to treat striae. Patients were more satisfied with microneedling than cryoroller.","PeriodicalId":42454,"journal":{"name":"Turk Dermatoloji Dergisi-Turkish Journal of Dermatology","volume":"113 1","pages":"11 - 15"},"PeriodicalIF":0.1,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82479307","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ö. Bilaç, C. Bilaç, A. Tahıllıoğlu, A. Uzun, Merve Dilcan, A. Önder, Canem Kavurma, Gülçin Uzunoğlu
Background: Acne vulgaris (AV) is a very common dermatological problem during adolescence. It is reported that it has a multifactorial etiology and nutritional attitudes, insufficient and poor-quality sleep may cause increased severity of AV. Aim: We aimed to investigate the sleep, eating attitudes and personality traits, and their effects on acne severity in adolescents with acne. Methods: The study sample was formed of 37 adolescent girls aged 12–18 years who presented at the University Dermatology Clinic and were diagnosed with AV and 37 adolescents without AV-matched age and gender. Eating attitude test, Diagnostic and Statistical Manual of Mental Disorders-5 (DSM-5) Personality Inventory Child Form, and child and parent forms of DSM-5 Level 2 Sleep Disorders were applied to in both groups. The AV severity assessed by using the Global Acne Grading Scale (GAGS). Psychiatric diagnosis was excluded with clinical interview according to the Schedule for Affective Disorders and Schizophrenia for school-aged children: Present and Lifetime Version (K-SADS-PL-DSM-5-T). Results: The mean age of adolescents with and without AV was 15.3 (standard deviation [SD] = 1.7), 15.4 (SD = 1.8), respectively. The mean disease duration of adolescents with AV was 20.4 (SD = 15.2) months, and the mean GAGS score was 23.24 (SD = 9.4). It was determined that eating attitudes, sleep, and personality characteristics of adolescents were similar in both groups. Eating attitudes, sleep, and personality characteristics had no direct effect on acne severity. Conclusion: Although this study demonstrates that eating attitudes, sleep, and personality characteristics were similar in adolescents with and without AV and these variables had no effect on acne severity, these results may have been obtained because of the severity scores of adolescents with AV were “moderate.” There is a need for researches examining these variables in adolescents with “severe” AV.
{"title":"The eating attitudes, sleep and personality characteristics, and effects of on acne severity in adolescents with acne vulgaris","authors":"Ö. Bilaç, C. Bilaç, A. Tahıllıoğlu, A. Uzun, Merve Dilcan, A. Önder, Canem Kavurma, Gülçin Uzunoğlu","doi":"10.4103/tjd.tjd_6_21","DOIUrl":"https://doi.org/10.4103/tjd.tjd_6_21","url":null,"abstract":"Background: Acne vulgaris (AV) is a very common dermatological problem during adolescence. It is reported that it has a multifactorial etiology and nutritional attitudes, insufficient and poor-quality sleep may cause increased severity of AV. Aim: We aimed to investigate the sleep, eating attitudes and personality traits, and their effects on acne severity in adolescents with acne. Methods: The study sample was formed of 37 adolescent girls aged 12–18 years who presented at the University Dermatology Clinic and were diagnosed with AV and 37 adolescents without AV-matched age and gender. Eating attitude test, Diagnostic and Statistical Manual of Mental Disorders-5 (DSM-5) Personality Inventory Child Form, and child and parent forms of DSM-5 Level 2 Sleep Disorders were applied to in both groups. The AV severity assessed by using the Global Acne Grading Scale (GAGS). Psychiatric diagnosis was excluded with clinical interview according to the Schedule for Affective Disorders and Schizophrenia for school-aged children: Present and Lifetime Version (K-SADS-PL-DSM-5-T). Results: The mean age of adolescents with and without AV was 15.3 (standard deviation [SD] = 1.7), 15.4 (SD = 1.8), respectively. The mean disease duration of adolescents with AV was 20.4 (SD = 15.2) months, and the mean GAGS score was 23.24 (SD = 9.4). It was determined that eating attitudes, sleep, and personality characteristics of adolescents were similar in both groups. Eating attitudes, sleep, and personality characteristics had no direct effect on acne severity. Conclusion: Although this study demonstrates that eating attitudes, sleep, and personality characteristics were similar in adolescents with and without AV and these variables had no effect on acne severity, these results may have been obtained because of the severity scores of adolescents with AV were “moderate.” There is a need for researches examining these variables in adolescents with “severe” AV.","PeriodicalId":42454,"journal":{"name":"Turk Dermatoloji Dergisi-Turkish Journal of Dermatology","volume":"17 1","pages":"5 - 10"},"PeriodicalIF":0.1,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79324188","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: Oral isotretinoin is a highly effective and widely used therapeutic agent for acne; however, it requires close follow-up due to its potential to produce various side effects. Slightly increased levels of serum creatine kinase (CK) that are either associated or not associated with musculoskeletal symptoms have been commonly reported and are typically considered innocuous. Objectives: The aims of the study are to investigate the frequency of our acne vulgaris patients with elevated serum CK levels during isotretinoin treatment, to analyze their course, and to determine the potential risk factors. Materials and Methods: Data of the patients in an outpatient clinic who were treated with isotretinoin due to acne vulgaris were retrospectively analyzed. Results: A total of 154 patients with at least 3 months of follow-up were included in the study. Elevated serum CK levels were found in 31 patients, and two patients had elevated levels over 1000 IU/l. While male sex was found to be a significant risk factor of CK elevation (P < 0.001), the mean age during the therapy was not found to be significantly different between the two groups. Of the patients with elevated serum CK levels, 16.2% were symptomatic and 29% had a recent history of physical exercise. Conclusions: Although mild elevation of serum CK has a benign course and is not uncommon among acne vulgaris patients who are treated with isotretinoin, remarkable elevations and symptomatic cases are relatively rare. Even CK elevations of more than 1000 IU/l may occur without symptomatic rhabdomyolysis if they are triggered by strenuous physical exercise or other causes during isotretinoin treatment. Further investigation of whether an agreed upon and not currently recommended upper limit for CK level that is tolerable can ensure safer follow-up during isotretinoin treatment is needed.
{"title":"Elevated serum creatine kinase levels in acne vulgaris patients treated with isotretinoin: A retrospective single-center study","authors":"S. Sayar","doi":"10.4103/tjd.tjd_2_21","DOIUrl":"https://doi.org/10.4103/tjd.tjd_2_21","url":null,"abstract":"Background: Oral isotretinoin is a highly effective and widely used therapeutic agent for acne; however, it requires close follow-up due to its potential to produce various side effects. Slightly increased levels of serum creatine kinase (CK) that are either associated or not associated with musculoskeletal symptoms have been commonly reported and are typically considered innocuous. Objectives: The aims of the study are to investigate the frequency of our acne vulgaris patients with elevated serum CK levels during isotretinoin treatment, to analyze their course, and to determine the potential risk factors. Materials and Methods: Data of the patients in an outpatient clinic who were treated with isotretinoin due to acne vulgaris were retrospectively analyzed. Results: A total of 154 patients with at least 3 months of follow-up were included in the study. Elevated serum CK levels were found in 31 patients, and two patients had elevated levels over 1000 IU/l. While male sex was found to be a significant risk factor of CK elevation (P < 0.001), the mean age during the therapy was not found to be significantly different between the two groups. Of the patients with elevated serum CK levels, 16.2% were symptomatic and 29% had a recent history of physical exercise. Conclusions: Although mild elevation of serum CK has a benign course and is not uncommon among acne vulgaris patients who are treated with isotretinoin, remarkable elevations and symptomatic cases are relatively rare. Even CK elevations of more than 1000 IU/l may occur without symptomatic rhabdomyolysis if they are triggered by strenuous physical exercise or other causes during isotretinoin treatment. Further investigation of whether an agreed upon and not currently recommended upper limit for CK level that is tolerable can ensure safer follow-up during isotretinoin treatment is needed.","PeriodicalId":42454,"journal":{"name":"Turk Dermatoloji Dergisi-Turkish Journal of Dermatology","volume":"2016 1","pages":"1 - 4"},"PeriodicalIF":0.1,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86360400","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. Solak, Haydar Yöndem, Y. Urun, Mert Cezik, N. Can
Background: The characteristics of cutaneous squamous cell carcinoma (cSCC) may show differences according to the geographic distribution and ethnicity. Although most cSCCs are treated with surgical excision or other local interventions, high-risk cSCCs may have poor outcome. In the present study, we aimed to evaluate the clinicopathological characteristics and determine the high-risk features of cSCCs in the Thrace region of Turkey where the information on cSCCs is scarce. Methods: We retrospectively investigated the biopsy-proven cSCCs diagnosed between the years 2014 and 2018, in a tertiary university hospital and evaluated the high-risk features. Results: A total of 211 cSCCs were included. Men with cSCC were significantly younger than women with cSCC (P <.001). Almost one-half of the tumors (n = 103) were located on the lower lip. Patients with a cSCC on the lower lip were younger than those with a cSCC on the other sites. All patients with a cSCC on the ears were men. Twenty-eight percent of patients had tumor size more than 20 mm and 28% had tumor thickness more than 6 mm. Immunosuppression was present in 7.6% of patients. A total of 177 (83.9%) patients had high-risk cSCC. The local recurrence rate was 6.2%, and the metastasis rate was 5.2%. Conclusions: The Thrace region has significant number of cSCC, and high-risk features are very frequent. Clinicians should carefully evaluate the cSCCs in terms of high-risk features.
{"title":"High prevalence of high-risk cutaneous squamous cell carcinoma in the thrace region of Turkey","authors":"S. Solak, Haydar Yöndem, Y. Urun, Mert Cezik, N. Can","doi":"10.4103/tjd.tjd_103_20","DOIUrl":"https://doi.org/10.4103/tjd.tjd_103_20","url":null,"abstract":"Background: The characteristics of cutaneous squamous cell carcinoma (cSCC) may show differences according to the geographic distribution and ethnicity. Although most cSCCs are treated with surgical excision or other local interventions, high-risk cSCCs may have poor outcome. In the present study, we aimed to evaluate the clinicopathological characteristics and determine the high-risk features of cSCCs in the Thrace region of Turkey where the information on cSCCs is scarce. Methods: We retrospectively investigated the biopsy-proven cSCCs diagnosed between the years 2014 and 2018, in a tertiary university hospital and evaluated the high-risk features. Results: A total of 211 cSCCs were included. Men with cSCC were significantly younger than women with cSCC (P <.001). Almost one-half of the tumors (n = 103) were located on the lower lip. Patients with a cSCC on the lower lip were younger than those with a cSCC on the other sites. All patients with a cSCC on the ears were men. Twenty-eight percent of patients had tumor size more than 20 mm and 28% had tumor thickness more than 6 mm. Immunosuppression was present in 7.6% of patients. A total of 177 (83.9%) patients had high-risk cSCC. The local recurrence rate was 6.2%, and the metastasis rate was 5.2%. Conclusions: The Thrace region has significant number of cSCC, and high-risk features are very frequent. Clinicians should carefully evaluate the cSCCs in terms of high-risk features.","PeriodicalId":42454,"journal":{"name":"Turk Dermatoloji Dergisi-Turkish Journal of Dermatology","volume":"46 1","pages":"83 - 89"},"PeriodicalIF":0.1,"publicationDate":"2020-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79687400","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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