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An Event-Related Study for Dynamic Analysis of Corticomuscular Connectivity 皮质肌连通性动态分析的事件相关研究
IF 2.8 Pub Date : 2010-01-01 DOI: 10.4137/BECB.S5546
O. Bai, Dandan Huang, P. Lin, Jinglong Wu, Xuedong Chen, D. Fei
Corticomuscular coupling estimated by EEG-EMG coherence may reveal functional cortical driving of peripheral muscular activity. EEG-EMG coherence in the beta band (15–30 Hz) has been extensively studied under isometric muscle contraction tasks. We attempted to study the time-course of corticomuscular connectivity under a dynamic target tracking task. A new device was developed for the real-time measurement of dynamic force created by pinching thumb and index fingers. Four healthy subjects who participated in this study were asked to track visual targets with the feedback forces. Spectral parameters using FFT and complex wavelet were explored for reliable estimation of event-related coherence and EEG-EMG correlogram for representing corticomuscular connectivity. Clearly distinguishable FFT-based coherence and cross-correlogram during the visual target tracking were observed with appropriate hyper-parameters for spectral estimation. The system design and the exploration of signal processing methods in this study supports further exploration of corticomuscular connectivity associated with human motor control.
通过脑电图-肌电图相干性估计的皮质-肌肉耦合可能揭示外周肌肉活动的功能性皮质驱动。在等长肌肉收缩任务下,脑电图-肌电图在β波段(15-30 Hz)的相干性已被广泛研究。我们试图研究动态目标跟踪任务下皮质肌连通性的时间过程。研制了一种新的装置,用于实时测量由拇指和食指挤压产生的动态力。4名健康受试者被要求用反馈力跟踪视觉目标。利用FFT和复小波的频谱参数来可靠地估计事件相关相干性和代表皮质肌连通性的EEG-EMG相关图。利用适当的超参数进行光谱估计,观察到视觉目标跟踪过程中基于fft的相干性和互相关图有明显区别。本研究的系统设计和信号处理方法的探索为进一步探索与人类运动控制相关的皮质肌肉连接提供了支持。
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引用次数: 2
On Robust State Estimation of Gene Networks 基因网络的鲁棒状态估计
IF 2.8 Pub Date : 2010-01-01 DOI: 10.1177/117959721000200001
Chia-Hua Chuang, Chun‐Liang Lin
Gene networks in biological systems are not only nonlinear but also stochastic due to noise corruption. How to accurately estimate the internal states of the noisy gene networks is an attractive issue to researchers. However, the internal states of biological systems are mostly inaccessible by direct measurement. This paper intends to develop a robust extended Kalman filter for state and parameter estimation of a class of gene network systems with uncertain process noises. Quantitative analysis of the estimation performance is conducted and some representative examples are provided for demonstration.
由于噪声的破坏,生物系统中的基因网络不仅是非线性的,而且是随机的。如何准确估计噪声基因网络的内部状态一直是研究人员关注的问题。然而,生物系统的内部状态大多无法通过直接测量获得。针对一类具有不确定过程噪声的基因网络系统的状态和参数估计问题,提出了一种鲁棒扩展卡尔曼滤波器。对估计性能进行了定量分析,并给出了一些有代表性的实例进行论证。
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引用次数: 6
Biomedical Engineering and Computational Biology 生物医学工程与计算生物学
IF 2.8 Pub Date : 2009-01-01 DOI: 10.1177/117959720900100001
K. Najarian
This is an open access article distributed under the terms of the Creative Commons Attribution License (http://www.creativecommons.org/licenses/by/2.0) which permits unrestricted use, distribution and reproduction provided the original work is properly cited. Open Access Full open access to this and thousands of other papers at http://www.la-press.com. Biomedical Engineering and Computational Biology
这是一篇在知识共享署名许可(http://www.creativecommons.org/licenses/by/2.0)条款下发布的开放获取文章,该许可允许不受限制的使用、分发和复制,前提是正确引用原始作品。在http://www.la-press.com上完全开放获取这篇论文和其他数千篇论文。生物医学工程与计算生物学
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引用次数: 9
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Biomedical Engineering and Computational Biology
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