Pub Date : 2023-01-16DOI: 10.18051/univmed.2023.v42.6-11
S. H. Respati, Risang Bhaskoro, Eric Edwin Yuliantara, Uki Retno Budihastuti, Debree Septiawan
BackgroundPostpartum depression occurs in women after cesarean section, due to increased cortisol and decreased prolactin levels, leading to delayed breast milk production. Hypnotherapy is one of the most effective and efficient complementary therapy options for reducing postpartum depression. Hypnotherapy increases oxytocin secretion from the paraventricular nucleus of the anterior pituitary gland, decreases cortisol levels, and increases prolactin, thereby increasing breast milk production. This study evaluates hypnotherapy’s effect on prolactin levels after a cesarean section. MethodsThis study was an experimental non-blinded randomized controlled trial with a post-test-only control group design conducted at Dr. Moewardi General Hospital and UNS hospital. A total of 20 post-cesarean -section women were included in the study. They were randomized into two groups, a group I: given hypnotherapy, and group 2: the control group (without hypnotherapy). Both groups were tested for prolactin levels. Group I received hypnotherapy 6 to 12 hours post-cesarean section, and study participants were confirmed to be unaffected by the anesthetic. Data analysis used the independent t-test and p<0.05. ResultsAt baseline, there was no significant difference in age, parity, and indication for cesarean section between the hypnotherapy and the control groups (p>0.05). After intervention, the mean prolactin level was higher in the hypnotherapy group (247.6 ± 81.1 ng/mL) compared to the control group (120.1 ± 55.4 ng/mL) (p<0.001). ConclusionHypnotherapy increases post-cesarean prolactin levels compared to the controls. Our findings open up a wide range of potential hypnotic applications among women with postpartum depression.
{"title":"Effect of hypnotherapy on prolactin level in women after cesarean section","authors":"S. H. Respati, Risang Bhaskoro, Eric Edwin Yuliantara, Uki Retno Budihastuti, Debree Septiawan","doi":"10.18051/univmed.2023.v42.6-11","DOIUrl":"https://doi.org/10.18051/univmed.2023.v42.6-11","url":null,"abstract":"BackgroundPostpartum depression occurs in women after cesarean section, due to increased cortisol and decreased prolactin levels, leading to delayed breast milk production. Hypnotherapy is one of the most effective and efficient complementary therapy options for reducing postpartum depression. Hypnotherapy increases oxytocin secretion from the paraventricular nucleus of the anterior pituitary gland, decreases cortisol levels, and increases prolactin, thereby increasing breast milk production. This study evaluates hypnotherapy’s effect on prolactin levels after a cesarean section.\u0000MethodsThis study was an experimental non-blinded randomized controlled trial with a post-test-only control group design conducted at Dr. Moewardi General Hospital and UNS hospital. A total of 20 post-cesarean -section women were included in the study. They were randomized into two groups, a group I: given hypnotherapy, and group 2: the control group (without hypnotherapy). Both groups were tested for prolactin levels. Group I received hypnotherapy 6 to 12 hours post-cesarean section, and study participants were confirmed to be unaffected by the anesthetic. Data analysis used the independent t-test and p<0.05.\u0000ResultsAt baseline, there was no significant difference in age, parity, and indication for cesarean section between the hypnotherapy and the control groups (p>0.05). After intervention, the mean prolactin level was higher in the hypnotherapy group (247.6 ± 81.1 ng/mL) compared to the control group (120.1 ± 55.4 ng/mL) (p<0.001).\u0000ConclusionHypnotherapy increases post-cesarean prolactin levels compared to the controls. Our findings open up a wide range of potential hypnotic applications among women with postpartum depression.","PeriodicalId":42578,"journal":{"name":"Universa Medicina","volume":" ","pages":""},"PeriodicalIF":0.3,"publicationDate":"2023-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46129438","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
BACKGROUNDThe increasing trend of working from home (WFH) among workers may lead to prolonged sitting time, which is associated with increased complaints of low back pain (LBP). The lumbosacral angle (LSA) is one of the clinically important radiographic angles related to the curves commonly measured to evaluate the biomechanical factors linked with LBP. The purpose of this study was to determine the yield of radiographic LSA for diagnosing LBP among workers aged 20-70 years. METHODS An analytic cross-sectional study involving 119 participants was carried out in Trisakti University. Lumbosacral angle was measured using Ferguson’s method. Data regarding LBP symptoms, sitting duration, and sitting position were collected using a questionnaire. Sensitivity and specificity was used to describe the characteristics of LSA as a screening test of LBP. RESULTSThe subjects consisted of 66 women (55.5%) and 53 men (44.5 %). Their ages ranged from 20 to 64 years with a median age of 40.0 years. Mean LSA was 37.4 ± 7.3º, while the prevalence of LBP was 75 (63.0%). The optimal cut-off value of LSA for the prediction of LBP was 49.5% (95% CI: 0.385-0.606). The sensitivity, specificity, positive predictive value and negative predictive value of LSA in detecting LBP were 58.7%, 45.5%, 68.8%, and 43.6%. CONCLUSIONSThe radiographic lumbosacral angle has a low yield for the diagnosis of LBP among workers aged 20-70 years. Further studies are needed to confirm our results and to test the application of this measurement.
{"title":"Radiographic lumbosacral angle has a low yield for diagnosing low back pain in workers 20-70 years of age","authors":"Partogi Napitupulu, Gupita Nareswari, Mulia Rahmansyah, Tandy Chintya Tanaji","doi":"10.18051/univmed.2022.v41.263-270","DOIUrl":"https://doi.org/10.18051/univmed.2022.v41.263-270","url":null,"abstract":"BACKGROUNDThe increasing trend of working from home (WFH) among workers may lead to prolonged sitting time, which is associated with increased complaints of low back pain (LBP). The lumbosacral angle (LSA) is one of the clinically important radiographic angles related to the curves commonly measured to evaluate the biomechanical factors linked with LBP. The purpose of this study was to determine the yield of radiographic LSA for diagnosing LBP among workers aged 20-70 years.\u0000METHODS An analytic cross-sectional study involving 119 participants was carried out in Trisakti University. Lumbosacral angle was measured using Ferguson’s method. Data regarding LBP symptoms, sitting duration, and sitting position were collected using a questionnaire. Sensitivity and specificity was used to describe the characteristics of LSA as a screening test of LBP.\u0000RESULTSThe subjects consisted of 66 women (55.5%) and 53 men (44.5 %). Their ages ranged from 20 to 64 years with a median age of 40.0 years. Mean LSA was 37.4 ± 7.3º, while the prevalence of LBP was 75 (63.0%). The optimal cut-off value of LSA for the prediction of LBP was 49.5% (95% CI: 0.385-0.606). The sensitivity, specificity, positive predictive value and negative predictive value of LSA in detecting LBP were 58.7%, 45.5%, 68.8%, and 43.6%.\u0000CONCLUSIONSThe radiographic lumbosacral angle has a low yield for the diagnosis of LBP among workers aged 20-70 years. Further studies are needed to confirm our results and to test the application of this measurement.","PeriodicalId":42578,"journal":{"name":"Universa Medicina","volume":" ","pages":""},"PeriodicalIF":0.3,"publicationDate":"2022-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44159161","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-12-19DOI: 10.18051/univmed.2022.v41.302-314
A. Majnooni, S. A. Jamedar, A. Azimian, K. Ghazvini
BackgroundChlamydia trachomatis (CT) and Neisseria gonorrhoeae (NG) are commonly diagnosed sexually transmitted infections that have been associated with serious reproductive health outcomes for women. The association of CT and NG infection with female fertility is not completely established yet. This review aimed to determine the association of CT and NG with female infertility. MethodsThis systematic review and meta-analysis was conducted according to the PRISMA statement. We searched a range of electronic databases, including PubMed, Web of Science, Embase, and Scopus, from Sept 25, 2017 until February 1, 2021. From the 851 studies screened, 552 that failed to meet our eligibility criteria were excluded. Subsequently, we removed 290 studies for not having a possible correlation of CT and NG infections with female infertility. Nine studies comprising 1827 infertile patients met our inclusion criteria. Two investigators independently extracted a range of data. All analyses were performed using STATA (version 13.1, Stata Corp, College Station, TX, USA). ResultsCT infection potentiates female infertility, as 76.47% of the included studies found a positive correlation between them. However, due to the limited number of reported data, we were not able to compare NG infection prevalence in fertile and non-fertile patients. Overall prevalences of CT and NG infections among infertile patients were 12 % and 3%, respectively, while CT infection prevalence among the fertile group was 7%. Conclusion The prevalences of CT and NG infections were high in infertile women. Screening and treatment of C. trachomatis and gonococcal infections during infertility treatment might increase the pregnancy rate.
沙眼衣原体(CT)和淋病奈瑟菌(NG)是常见的性传播感染，与妇女严重的生殖健康后果有关。CT和NG感染与女性生育能力的关系尚未完全确定。本综述旨在确定CT和NG与女性不孕症的关系。方法按照PRISMA标准进行系统评价和meta分析。从2017年9月25日至2021年2月1日，我们检索了一系列电子数据库，包括PubMed、Web of Science、Embase和Scopus。从筛选的851项研究中，552项不符合我们的资格标准被排除。随后，我们删除了290项未发现CT和NG感染与女性不孕症可能相关的研究。包括1827名不孕症患者的9项研究符合我们的纳入标准。两名调查人员独立提取了一系列数据。所有分析均使用STATA(版本13.1,STATA Corp, College Station, TX, USA)进行。结果sct感染增强了女性不孕症，76.47%的纳入研究发现两者呈正相关。然而，由于报道的数据数量有限，我们无法比较生殖力患者和非生殖力患者的NG感染患病率。不孕症患者的CT和NG感染的总体患病率分别为12%和3%，而可育组的CT感染患病率为7%。结论不孕症妇女CT和NG感染率较高。在不孕症治疗期间筛查和治疗沙眼衣原体和淋球菌感染可能会增加妊娠率。
{"title":"Association of Chlamydia trachomatis and Neisseria gonorrhoeae with female infertility: a systematic review and meta-analysis","authors":"A. Majnooni, S. A. Jamedar, A. Azimian, K. Ghazvini","doi":"10.18051/univmed.2022.v41.302-314","DOIUrl":"https://doi.org/10.18051/univmed.2022.v41.302-314","url":null,"abstract":"BackgroundChlamydia trachomatis (CT) and Neisseria gonorrhoeae (NG) are commonly diagnosed sexually transmitted infections that have been associated with serious reproductive health outcomes for women. The association of CT and NG infection with female fertility is not completely established yet. This review aimed to determine the association of CT and NG with female infertility.\u0000MethodsThis systematic review and meta-analysis was conducted according to the PRISMA statement. We searched a range of electronic databases, including PubMed, Web of Science, Embase, and Scopus, from Sept 25, 2017 until February 1, 2021. From the 851 studies screened, 552 that failed to meet our eligibility criteria were excluded. Subsequently, we removed 290 studies for not having a possible correlation of CT and NG infections with female infertility. Nine studies comprising 1827 infertile patients met our inclusion criteria. Two investigators independently extracted a range of data. All analyses were performed using STATA (version 13.1, Stata Corp, College Station, TX, USA).\u0000ResultsCT infection potentiates female infertility, as 76.47% of the included studies found a positive correlation between them. However, due to the limited number of reported data, we were not able to compare NG infection prevalence in fertile and non-fertile patients. Overall prevalences of CT and NG infections among infertile patients were 12 % and 3%, respectively, while CT infection prevalence among the fertile group was 7%.\u0000Conclusion The prevalences of CT and NG infections were high in infertile women. Screening and treatment of C. trachomatis and gonococcal infections during infertility treatment might increase the pregnancy rate.","PeriodicalId":42578,"journal":{"name":"Universa Medicina","volume":" ","pages":""},"PeriodicalIF":0.3,"publicationDate":"2022-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44078504","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-12-14DOI: 10.18051/univmed.2022.v41.254-262
F. Ozdemir, Seda Karaçay Yıkar, E. Nazik
BackgroundBreastfeeding is critical for infant health and development globally. Current knowledge and attitude of future parents will significantly influence breastfeeding practices. The study was conducted to determine the levels and determinants of breastfeeding self-efficacy among primiparous and secundigravid adolescents. MethodsA cross-sectional study was performed involving 54 primiparous and secundigravid adolescents in antenatal clinics of hospitals affiliated to the Ministry of Health in Adana, Turkey. They were aged between 16 and 19 years, had a single living fetus, did not have pregnancy complications, were in their third trimester of pregnancy, attended an antenatal clinic, and agreed to participate in the study. Data were collected using a Personal Information Form and the Antenatal Breastfeeding Self-Efficacy Short Form Scale (BSES-SF). Kruskal-Wallis variance analysis, Mann Whitney U and multiple linear regression analysis test were used to analyze the data. ResultsMean age of the pregnant adolescents was 18.28 ± 0.79 years, and 31.5% had primary education, 96.3% were not working, 55.6% lived in a nuclear family, and 51.9% had not received breastfeeding education. The total BSES-SF mean score was 55.37 ± 12.84. Breastfeeding education has a statistically significant effect on breastfeeding self-efficacy of pregnant adolescents (p<0.05). Regular antenatal care, breastfeeding training status, breastfeeding education source variables and breastfeeding self-efficacy variable of women significantly predicted negatively (p<0.05). ConclusionsBreastfeeding education source was the most influential predictor variable of BSES. There is a need for nursing initiatives to enhance the adolescents’ antenatal breastfeeding self-efficacy levels.
{"title":"Predictors of breastfeeding self-efficacy in pregnant adolescents","authors":"F. Ozdemir, Seda Karaçay Yıkar, E. Nazik","doi":"10.18051/univmed.2022.v41.254-262","DOIUrl":"https://doi.org/10.18051/univmed.2022.v41.254-262","url":null,"abstract":"BackgroundBreastfeeding is critical for infant health and development globally. Current knowledge and attitude of future parents will significantly influence breastfeeding practices. The study was conducted to determine the levels and determinants of breastfeeding self-efficacy among primiparous and secundigravid adolescents.\u0000MethodsA cross-sectional study was performed involving 54 primiparous and secundigravid adolescents in antenatal clinics of hospitals affiliated to the Ministry of Health in Adana, Turkey. They were aged between 16 and 19 years, had a single living fetus, did not have pregnancy complications, were in their third trimester of pregnancy, attended an antenatal clinic, and agreed to participate in the study. Data were collected using a Personal Information Form and the Antenatal Breastfeeding Self-Efficacy Short Form Scale (BSES-SF). Kruskal-Wallis variance analysis, Mann Whitney U and multiple linear regression analysis test were used to analyze the data.\u0000ResultsMean age of the pregnant adolescents was 18.28 ± 0.79 years, and 31.5% had primary education, 96.3% were not working, 55.6% lived in a nuclear family, and 51.9% had not received breastfeeding education. The total BSES-SF mean score was 55.37 ± 12.84. Breastfeeding education has a statistically significant effect on breastfeeding self-efficacy of pregnant adolescents (p<0.05). Regular antenatal care, breastfeeding training status, breastfeeding education source variables and breastfeeding self-efficacy variable of women significantly predicted negatively (p<0.05).\u0000ConclusionsBreastfeeding education source was the most influential predictor variable of BSES. There is a need for nursing initiatives to enhance the adolescents’ antenatal breastfeeding self-efficacy levels.","PeriodicalId":42578,"journal":{"name":"Universa Medicina","volume":"1 1","pages":""},"PeriodicalIF":0.3,"publicationDate":"2022-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41351216","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-12-13DOI: 10.18051/univmed.2022.v41.246-253
I. Somia, T. Merati, D. Sukmawati, N. Winarti, I. E. Indira, Ida Bagus Dwija Putra, Made Yogi Oktavian Prasetia
BACKGROUND Anal human papillomavirus (HPV) is associated with the severity of anal cytologic abnormalities that are precancerous lesions. Knowledge of HPV type distribution in populations at risk for anal cancer is needed. This study investigated anal HPV infections and cytological abnormalities among men who have sex with men (MSM). METHODS A cross-sectional study was conducted involving 90 men aged >30 years with a history of anal sexual intercourse with men. Demographic characteristics and sexual behaviors were collected by using a self-completed questionnaire. Anal cytological results were examined, and HPV genotyping was performed by the Linear Array HPV genotyping test. Descriptive analyses of subject characteristics, prevalence, and 95% confidence intervals (CI) were performed. A chi-square test was used to determine their associations with high-risk HPV infection and cytological abnormalities. RESULTS The overall prevalence of abnormal cytology was 32% (24/75), atypical squamous cells of undetermined significance (ASCUS) 17.33 % (13/75), 14.66% (11/75) were classified as low-grade SIL (LSIL) and no participant had high-grade SIL (HSIL). Prevalence of HPV infection with normal cytology was 86.27% (44/51), ASCUS 92.30% (12/13), and LSIL 100% (11/11). The most common types of anal HPV in participants with cytological abnormalities are HPV 16, HPV 18 for high-risk HPV, and HPV 11, HPV 6 for low-risk HPV. There were no associations between the predictor variables and the abnormal cytology (p>0.05). CONCLUSION There was a high prevalence of HPV infection in MSM with abnormal anal cytology. A routine anal Pap smear program and vaccination are needed to prevent HPV infection and anal dysplasia in MSM.
{"title":"Anal human papillomavirus genotype distribution and its associations with abnormal anal cytology among men who have sex with men","authors":"I. Somia, T. Merati, D. Sukmawati, N. Winarti, I. E. Indira, Ida Bagus Dwija Putra, Made Yogi Oktavian Prasetia","doi":"10.18051/univmed.2022.v41.246-253","DOIUrl":"https://doi.org/10.18051/univmed.2022.v41.246-253","url":null,"abstract":"BACKGROUND Anal human papillomavirus (HPV) is associated with the severity of anal cytologic abnormalities that are precancerous lesions. Knowledge of HPV type distribution in populations at risk for anal cancer is needed. This study investigated anal HPV infections and cytological abnormalities among men who have sex with men (MSM).\u0000METHODS A cross-sectional study was conducted involving 90 men aged >30 years with a history of anal sexual intercourse with men. Demographic characteristics and sexual behaviors were collected by using a self-completed questionnaire. Anal cytological results were examined, and HPV genotyping was performed by the Linear Array HPV genotyping test. Descriptive analyses of subject characteristics, prevalence, and 95% confidence intervals (CI) were performed. A chi-square test was used to determine their associations with high-risk HPV infection and cytological abnormalities.\u0000RESULTS The overall prevalence of abnormal cytology was 32% (24/75), atypical squamous cells of undetermined significance (ASCUS) 17.33 % (13/75), 14.66% (11/75) were classified as low-grade SIL (LSIL) and no participant had high-grade SIL (HSIL). Prevalence of HPV infection with normal cytology was 86.27% (44/51), ASCUS 92.30% (12/13), and LSIL 100% (11/11). The most common types of anal HPV in participants with cytological abnormalities are HPV 16, HPV 18 for high-risk HPV, and HPV 11, HPV 6 for low-risk HPV. There were no associations between the predictor variables and the abnormal cytology (p>0.05).\u0000CONCLUSION There was a high prevalence of HPV infection in MSM with abnormal anal cytology. A routine anal Pap smear program and vaccination are needed to prevent HPV infection and anal dysplasia in MSM.","PeriodicalId":42578,"journal":{"name":"Universa Medicina","volume":" ","pages":""},"PeriodicalIF":0.3,"publicationDate":"2022-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46599982","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-10-28DOI: 10.18051/univmed.2022.v41.236-245
Sulistyowati Tuminah Darjoko, S. Ronoatmodjo, Srilaning Driyah, Dewi Kristanti, D. H. Tjandrarini
BACKGROUNDDyslipidemia is of global occurrence, with a prevalence 30% or higher in several countries, including Indonesia. One risk factor of dyslipidemia is physical or mental stress, that is more frequent in women. This study aimed at investigating the association between psychological distress and dyslipidemia in adult women. METHODSThis observational longitudinal study involved 1850 women aged 25 years and older at baseline. Dyslipidemia was determined from the ratio of low- density lipoprotein to high-density lipoprotein. Psychological distress was determined using the 20-item self-reporting questionnaire. Data analysis was by Cox regression for calculating the hazard ratio of the incidence of dyslipidemia as predicted by the psychological distress. RESULTSAmong the 1474 participants without dyslipidemia at baseline, 545 (36.9%) developed dyslipidemia during 6 years of monitoring, while 93 (6.3%) had a history of psychological distress. There was a significant association between psychological distress and dyslipidemia (HR = 3.08; 95% CI: 2.33- 4.07). Cox regression revealed that the association was still found to be significant after a further adjustment for the variables of age, BMI, menopause, smoking status, physical activity, and carbohydrate and fat intakes (HR=2.8; 95% CI: 2.10 - 3.77). CONCLUSIONSDyslipidemia incidence was high among adult women in Bogor. Women with psychological distress had higher incidence rates of dyslipidemia than women without psychological distress. Psychological distress in women was statistically significantly associated with incidence rate of dyslipidemia. This finding highlights the importance of the need for a dyslipidemia- reduction program in women through prevention and control of psychological distress.
{"title":"Psychological distress and dyslipidemia in adult women: A 6-years follow up study in Bogor City, Indonesia","authors":"Sulistyowati Tuminah Darjoko, S. Ronoatmodjo, Srilaning Driyah, Dewi Kristanti, D. H. Tjandrarini","doi":"10.18051/univmed.2022.v41.236-245","DOIUrl":"https://doi.org/10.18051/univmed.2022.v41.236-245","url":null,"abstract":"BACKGROUNDDyslipidemia is of global occurrence, with a prevalence 30% or higher in several countries, including Indonesia. One risk factor of dyslipidemia is physical or mental stress, that is more frequent in women. This study aimed at investigating the association between psychological distress and dyslipidemia in adult women.\u0000METHODSThis observational longitudinal study involved 1850 women aged 25 years and older at baseline. Dyslipidemia was determined from the ratio of low- density lipoprotein to high-density lipoprotein. Psychological distress was determined using the 20-item self-reporting questionnaire. Data analysis was by Cox regression for calculating the hazard ratio of the incidence of dyslipidemia as predicted by the psychological distress.\u0000RESULTSAmong the 1474 participants without dyslipidemia at baseline, 545 (36.9%) developed dyslipidemia during 6 years of monitoring, while 93 (6.3%) had a history of psychological distress. There was a significant association between psychological distress and dyslipidemia (HR = 3.08; 95% CI: 2.33- 4.07). Cox regression revealed that the association was still found to be significant after a further adjustment for the variables of age, BMI, menopause, smoking status, physical activity, and carbohydrate and fat intakes (HR=2.8; 95% CI: 2.10 - 3.77).\u0000CONCLUSIONSDyslipidemia incidence was high among adult women in Bogor. Women with psychological distress had higher incidence rates of dyslipidemia than women without psychological distress. Psychological distress in women was statistically significantly associated with incidence rate of dyslipidemia. This finding highlights the importance of the need for a dyslipidemia- reduction program in women through prevention and control of psychological distress.","PeriodicalId":42578,"journal":{"name":"Universa Medicina","volume":" ","pages":""},"PeriodicalIF":0.3,"publicationDate":"2022-10-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43608464","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-10-13DOI: 10.18051/UnivMed.2022.v41.228-235
G. Yılmazel, Emre Keles, Ayşe Çalmaz, Burcu DAYSAL GULER
BackgroundHerd immunity is necessary to control the coronavirus disease 2019 (COVID-19) pandemic. Unfortunately, attaining herd immunity is a significant challenge for current healthcare systems worldwide, and the prevalence of hesitancy toward COVID-19 remains high. The aim of this study was to determine pandemic vaccine hesitancy, attitudes towards COVID-19 vaccine and COVID-19 vaccine literacy level in vaccination period among unvaccinated young adults. MethodsThis cross-sectional study was carried out in the province of Çorum in Turkey. Unvaccinated young adults (n=860) between the ages of 18-30 studying medicine and non-medical sciences of a university were included in the study. Socio-demographic form, and the scales on Pandemic Vaccine Hesitancy, Attitudes towards the COVID-19 vaccine, COVID-19 vaccine literacy were used to collect the research data. The data were analyzed using percentages, median values, regression analysis. Results The study was completed with 860 participants. In the group, 73.8% were 18-24 years 67.7% were women and 68.0% were infected with the virus. The median scores from the pandemic vaccine hesitancy scale, vaccine literacy and vaccine attitudes were 33, 27 and 30 respectively. Use of social media in daily, vaccine literacy and COVID-19 vaccine attitude were effective factors on pandemic vaccine hesitancy (p<0.05). Negative attitude to vaccines was the most influenced risk factor of vaccine hesitancy (Beta = 0.248). ConclusionPandemic vaccine hesitancy is a phenomenon that coincides with low vaccine literacy and negative attitudes towards vaccines. COVID-19 vaccination information campaigns should promote group strategies, focusing on emphasising the safety of the vaccine and offer reassurance.
{"title":"Attitudes towards COVID-19 vaccination, vaccine hesitancy and vaccine literacy among unvaccinated young adults","authors":"G. Yılmazel, Emre Keles, Ayşe Çalmaz, Burcu DAYSAL GULER","doi":"10.18051/UnivMed.2022.v41.228-235","DOIUrl":"https://doi.org/10.18051/UnivMed.2022.v41.228-235","url":null,"abstract":"BackgroundHerd immunity is necessary to control the coronavirus disease 2019 (COVID-19) pandemic. Unfortunately, attaining herd immunity is a significant challenge for current healthcare systems worldwide, and the prevalence of hesitancy toward COVID-19 remains high. The aim of this study was to determine pandemic vaccine hesitancy, attitudes towards COVID-19 vaccine and COVID-19 vaccine literacy level in vaccination period among unvaccinated young adults.\u0000MethodsThis cross-sectional study was carried out in the province of Çorum in Turkey. Unvaccinated young adults (n=860) between the ages of 18-30 studying medicine and non-medical sciences of a university were included in the study. Socio-demographic form, and the scales on Pandemic Vaccine Hesitancy, Attitudes towards the COVID-19 vaccine, COVID-19 vaccine literacy were used to collect the research data. The data were analyzed using percentages, median values, regression analysis.\u0000Results The study was completed with 860 participants. In the group, 73.8% were 18-24 years 67.7% were women and 68.0% were infected with the virus. The median scores from the pandemic vaccine hesitancy scale, vaccine literacy and vaccine attitudes were 33, 27 and 30 respectively. Use of social media in daily, vaccine literacy and COVID-19 vaccine attitude were effective factors on pandemic vaccine hesitancy (p<0.05). Negative attitude to vaccines was the most influenced risk factor of vaccine hesitancy (Beta = 0.248).\u0000ConclusionPandemic vaccine hesitancy is a phenomenon that coincides with low vaccine literacy and negative attitudes towards vaccines. COVID-19 vaccination information campaigns should promote group strategies, focusing on emphasising the safety of the vaccine and offer reassurance.","PeriodicalId":42578,"journal":{"name":"Universa Medicina","volume":" ","pages":""},"PeriodicalIF":0.3,"publicationDate":"2022-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44546084","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-09-19DOI: 10.18051/univmed.2022.v41.289-301
S. Sulfiana, Febriana Catur Iswanti
Asthma is the most frequent noncommunicable disease and one of the leading causes of years lived with disability. Asthma has a severe impact on a patient's life, being able to disturb the activities of both children and adults. The morbidity and mortality of asthma may depend on the severity and progressiveness of the symptoms experienced by the patient. Different and complex pathomechanisms underline the pathology of asthma, in which the regulation of innate and adaptive immune responses plays a role. There is a complex interaction between immune cells including chemokines involved in the pathogenesis of asthma. Immune cell trafficking is orchestrated by a family of small proteins called chemokines. Leukocytes express cell-surface receptors that bind to chemokines and trigger transendothelial migration. This review article outlines the main role of chemokines in inflammatory reactions that occur in allergic asthma, based on the latest literature studies that have been published previously. The allergic reaction in asthma expresses various chemokines and their receptors. Chemokines including eotaxins (CCL11, CCL24, and CCL26), CCL2, CCL5, CCL17, and CCL22 regulate immune cells that under pathological conditions travel to the inflammatory site, mainly in the lung, to protect the body from pathogen invasion. Chemokines are released by a number of immune cells such as monocytes, dendritic cells, mast cells, and epithelial cells in the airway. The biological effects of chemokine production are enhanced by secreted cytokines when an allergic reaction occurs in asthma, such as IL-4, IL-5, and IL-13. Chemokines cause an accumulation of different inflammatory cells at the site of inflammation, which ultimately results in tissue damage to the airway. The inhibition of the reactions evoked by the interaction between chemokines and their receptors is considered a candidate for the development of potent therapeutic drugs for asthma in the future.
{"title":"Chemokines in allergic asthma inflammation","authors":"S. Sulfiana, Febriana Catur Iswanti","doi":"10.18051/univmed.2022.v41.289-301","DOIUrl":"https://doi.org/10.18051/univmed.2022.v41.289-301","url":null,"abstract":"Asthma is the most frequent noncommunicable disease and one of the leading causes of years lived with disability. Asthma has a severe impact on a patient's life, being able to disturb the activities of both children and adults. The morbidity and mortality of asthma may depend on the severity and progressiveness of the symptoms experienced by the patient. Different and complex pathomechanisms underline the pathology of asthma, in which the regulation of innate and adaptive immune responses plays a role. There is a complex interaction between immune cells including chemokines involved in the pathogenesis of asthma. Immune cell trafficking is orchestrated by a family of small proteins called chemokines. Leukocytes express cell-surface receptors that bind to chemokines and trigger transendothelial migration. This review article outlines the main role of chemokines in inflammatory reactions that occur in allergic asthma, based on the latest literature studies that have been published previously. The allergic reaction in asthma expresses various chemokines and their receptors. Chemokines including eotaxins (CCL11, CCL24, and CCL26), CCL2, CCL5, CCL17, and CCL22 regulate immune cells that under pathological conditions travel to the inflammatory site, mainly in the lung, to protect the body from pathogen invasion. Chemokines are released by a number of immune cells such as monocytes, dendritic cells, mast cells, and epithelial cells in the airway. The biological effects of chemokine production are enhanced by secreted cytokines when an allergic reaction occurs in asthma, such as IL-4, IL-5, and IL-13. Chemokines cause an accumulation of different inflammatory cells at the site of inflammation, which ultimately results in tissue damage to the airway. The inhibition of the reactions evoked by the interaction between chemokines and their receptors is considered a candidate for the development of potent therapeutic drugs for asthma in the future.","PeriodicalId":42578,"journal":{"name":"Universa Medicina","volume":" ","pages":""},"PeriodicalIF":0.3,"publicationDate":"2022-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46946559","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-09-06DOI: 10.18051/univmed.2022.v41.207-209
J. Aggarwal, Niharika Singh, J. Batra
There are multiple peripheral clocks located in various tissues and organs of the body, which cause variations in biological activities and are involved in the generation of circadian rhythms. In mammals
{"title":"Genetics of circadian rhythm in disease and aging process","authors":"J. Aggarwal, Niharika Singh, J. Batra","doi":"10.18051/univmed.2022.v41.207-209","DOIUrl":"https://doi.org/10.18051/univmed.2022.v41.207-209","url":null,"abstract":"There are multiple peripheral clocks located in various tissues and organs of the body, which cause variations in biological activities and are involved in the generation of circadian rhythms. In mammals","PeriodicalId":42578,"journal":{"name":"Universa Medicina","volume":" ","pages":""},"PeriodicalIF":0.3,"publicationDate":"2022-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43810989","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-09-02DOI: 10.18051/univmed.2022.v41.219-227
Selen Ozakar Akca, A. P. Turan, Dilek KALKAN YALCIN
BACKGROUNDFetal rights are violated due to acts such as negligence, ignorance, false beliefs and substance addiction. Pediatric nurses, as defenders of the fetus, should inform pregnant women and the family about the rights of the fetus and assist the family in the decision-making process. This study aims to determine the knowledge levels of pediatric nurses on fetal rights. METHODSThis cross-sectional study involved 121 nurses working in the pediatric clinic of a training and research hospital. Data about characteristics of pediatric nurses and knowledge levels about fetal rights were collected. Statistical analyses were made with SPSS package program. Mann Whitney U test and Kruskal Wallis test was used to analyse the data. RESULTSIn this study, it was found that 76.9% of the pediatric nurses participating in the study did not have prior knowledge about fetal rights. There was a statistically significant difference between the participants’ mean scores of knowledge levels about fetal rights and their age, educational status, status of prior knowledge about fetal rights and where this knowledge was gained (p<0.05). CONCLUSIONAs a result, it was found that most of the pediatric nurses did not have prior knowledge about fetal rights, and that their knowledge about fetal rights was lacking. Considering that pediatric nurses, as the defenders of the fetus, have a duty to inform the family about fetal rights, it is recommended to plan trainings on fetal rights for pediatric nurses.
{"title":"Knowledge levels of fetal rights in Turkish pediatric nurses","authors":"Selen Ozakar Akca, A. P. Turan, Dilek KALKAN YALCIN","doi":"10.18051/univmed.2022.v41.219-227","DOIUrl":"https://doi.org/10.18051/univmed.2022.v41.219-227","url":null,"abstract":"BACKGROUNDFetal rights are violated due to acts such as negligence, ignorance, false beliefs and substance addiction. Pediatric nurses, as defenders of the fetus, should inform pregnant women and the family about the rights of the fetus and assist the family in the decision-making process. This study aims to determine the knowledge levels of pediatric nurses on fetal rights.\u0000METHODSThis cross-sectional study involved 121 nurses working in the pediatric clinic of a training and research hospital. Data about characteristics of pediatric nurses and knowledge levels about fetal rights were collected. Statistical analyses were made with SPSS package program. Mann Whitney U test and Kruskal Wallis test was used to analyse the data.\u0000RESULTSIn this study, it was found that 76.9% of the pediatric nurses participating in the study did not have prior knowledge about fetal rights. There was a statistically significant difference between the participants’ mean scores of knowledge levels about fetal rights and their age, educational status, status of prior knowledge about fetal rights and where this knowledge was gained (p<0.05).\u0000CONCLUSIONAs a result, it was found that most of the pediatric nurses did not have prior knowledge about fetal rights, and that their knowledge about fetal rights was lacking. Considering that pediatric nurses, as the defenders of the fetus, have a duty to inform the family about fetal rights, it is recommended to plan trainings on fetal rights for pediatric nurses.","PeriodicalId":42578,"journal":{"name":"Universa Medicina","volume":" ","pages":""},"PeriodicalIF":0.3,"publicationDate":"2022-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47346208","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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