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INTRAMUSCULAR PHENYLEPHRINE DOSE COMPARISON FOR PREVENTION OF SPINAL ANESTHESIA INDUCED HYPOTENSION DURING CESAREAN SECTION: A PROSPECTIVE RANDOMIZED DOUBLE BLIND STUDY 剖宫产术中肌注苯肾上腺素预防腰麻低血压的剂量比较:一项前瞻性随机双盲研究
IF 0.3 Q4 MEDICINE, GENERAL & INTERNAL Pub Date : 2022-12-31 DOI: 10.35845/10.35845/kmuj.2022.22784
M. Shafiq, R. Ullah, Shahan Raza, Farrah Ashraf, Salma Jan, M. Shahid
OBJECTIVE: To determine the more effective dose of intramuscular (IM) Phenylephrine in preventing hypotension due to spinal anesthesia (SA) administered for cesarean section. METHODS: The study was conducted from January 1, 2020 to July 31, 2020, at Rehman Medical Institute, Peshawar, Pakistan. Sixty participants of American Society of Anesthesiologists (ASA) physical status 1 and 2, scheduled for elective cesarean section (CS) under SA were enrolled in this prospective double-blind study and randomized into two equal groups, P4-group and P8-group. P4-group received IM Phenylephrine 04 mg and P8-group received IM Phenylephrine 08 mg before SA. The incidence and intensity of hypotension, rescue doses of Phenylephrine and any adverse event, were recorded. Data collected was analyzed using Epi lnfo ™ version 7.2.5. RESULTS: Mean age of patients from P4-Group and P8-Group was 28.10±4.39 years and 28.33±4.95 years respectively. There were no statistically significant differences in the two groups with respect to demographic and clinical characteristics. Hypotension occurred in 33.3% (n=20/60) of participants. The incidence of hypotension in P4-group and P8-group were 46.7% (n=14/30) and 20% (n=6/30) respectively. In P8-group, risk of hypotension was 1.5 times less common compared with P4-group with 95% confidence interval of 1.02–2.19 (p=0.02). There was also no statistically significant difference between the onset of hypotension in the two groups. Those who developed hypotension had consumed a lesser amount of rescue Phenylephrine in P8-group compared with P4-group (p-value <0.01). CONCLUSION: Phenylephrine 08 mg IM preemptively controlled SA induced hypotension in a sustained way in the fit parturients.
目的:探讨肌注苯肾上腺素(IM)预防剖宫产术后腰麻低血压的更有效剂量。方法:研究于2020年1月1日至2020年7月31日在巴基斯坦白沙瓦Rehman医学研究所进行。选择美国麻醉医师学会(ASA)生理状态为1和2的60名在SA下计划择期剖宫产术(CS)的患者进行前瞻性双盲研究,随机分为p4组和p8组。p4组注射苯肾上腺素04 mg, p8组注射苯肾上腺素08 mg。记录低血压的发生率和强度、苯肾上腺素的抢救剂量及任何不良事件。使用Epi info™版本7.2.5分析收集的数据。结果:p4组和p8组患者的平均年龄分别为28.10±4.39岁和28.33±4.95岁。两组在人口学和临床特征方面无统计学差异。33.3% (n=20/60)的参与者出现低血压。p4组和p8组低血压发生率分别为46.7% (n=14/30)和20% (n=6/30)。p8组低血压发生率为p4组的1.5倍,95%可信区间为1.02 ~ 2.19 (p=0.02)。两组的低血压发生率也无统计学差异。与p4组相比,p8组出现低血压的患者消耗的抢救用苯肾上腺素较少(p值<0.01)。结论:苯肾上腺素08 mg IM对SA致低血压有持续的预防作用。
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引用次数: 0
DIAGNOSTIC ACCURACY OF ULTRASOUND IN EARLY DETECTION OF MOLAR PREGNANCY 超声早期诊断磨牙妊娠的准确性
IF 0.3 Q4 MEDICINE, GENERAL & INTERNAL Pub Date : 2022-12-31 DOI: 10.35845/kmuj.2022.21651
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引用次数: 0
TRUE LEFT SIDED GALL BLADDER: A SURGICAL SURPRISE 真正的左侧胆囊:外科手术的惊喜
IF 0.3 Q4 MEDICINE, GENERAL & INTERNAL Pub Date : 2022-12-31 DOI: 10.35845/kmuj.2022.23122
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引用次数: 0
USING HEALTH INSURANCE DATABASES FOR EPIDEMIOLOGICAL RESEARCH: A SCOPING REVIEW 使用健康保险数据库进行流行病学研究:范围审查
IF 0.3 Q4 MEDICINE, GENERAL & INTERNAL Pub Date : 2022-12-31 DOI: 10.35845/kmuj.2022.21480
Sheraz Ahmad, Khan Raheel Shahab, A. Khan, Jamil
OBJECTIVES: This scoping review aimed to appraise the existing literature on using the claims databases for epidemiological studies and to draw inferences for using data from Pakistan's health insurance databases. METHODS: We conducted a scoping review of literature focusing on health insurance databases, querying MEDLINE, EMBASE and Google Scholar. We used the frameworks proposed by the Joanna Briggs Institute and Arksy and O'Malley for mapping our results. RESULTS: There was a considerable chronological increase in studies published using data from health insurance databases. Most of the studies in our search were from economically developed countries. Most of the studies (n=84) focussed on chronic non-communicable diseases, while a limited number (n=09) focussed on communicable (infectious) diseases. Our findings suggest that insurance databases could be utilised to study rare diseases, prospects of prolonged follow-up, and minimal research costs. This is especially important for countries like Pakistan, having limited resources to conduct regular, population-level epidemiological studies. Several methodological approaches (for instance, disease, pharmacy or intervention classification codes) were presented in these studies to extract epidemiological data from the insurance database. CONCLUSION: Health insurance databases are utilised as sources for epidemiological studies, predominantly for chronic illnesses, in economically developed countries. Methodological approaches described in these papers could be used to extract data for epidemiological research from health insurance databases in Pakistan. This could be especially useful for following the patterns of infectious disease in the country.
目标:本范围审查旨在评估使用索赔数据库进行流行病学研究的现有文献,并对使用巴基斯坦健康保险数据库的数据进行推断。方法:我们对健康保险数据库、MEDLINE、EMBASE和Google Scholar的文献进行了范围审查。我们使用乔安娜·布里格斯研究所和Arksy和O'Malley提出的框架来绘制我们的结果。结果:使用健康保险数据库数据发表的研究在时间上有相当大的增长。我们搜索的大多数研究都来自经济发达国家。大多数研究(n=84)侧重于慢性非传染性疾病,而少数研究(n=09)侧重于传染性疾病。我们的研究结果表明,保险数据库可以用于研究罕见病、长期随访的前景和最低的研究成本。这对巴基斯坦这样的国家来说尤其重要,因为它们进行定期人口流行病学研究的资源有限。这些研究中提出了几种方法论方法(例如,疾病、药学或干预分类代码),以从保险数据库中提取流行病学数据。结论:在经济发达国家,健康保险数据库被用作流行病学研究的来源,主要用于慢性病。这些论文中描述的方法论方法可用于从巴基斯坦的医疗保险数据库中提取流行病学研究数据。这对于追踪该国的传染病模式尤其有用。
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引用次数: 0
CYBERCHONDRIA: ROLE OF POTENTIAL RISK FACTORS 网络疑病:潜在危险因素的作用
IF 0.3 Q4 MEDICINE, GENERAL & INTERNAL Pub Date : 2022-12-31 DOI: 10.35845/kmuj.2022.22920
Iram Batool, Huma Batool
,
,
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引用次数: 0
DYNAMIC SMILE EVALUATION IN ALL THREE SKELETAL PATTERNS 三种骨骼模式的动态微笑评估
IF 0.3 Q4 MEDICINE, GENERAL & INTERNAL Pub Date : 2022-12-31 DOI: 10.35845/kmuj.2022.22108
Zainab Ahmed, Z. H. Awaisi, Zubair Ahmed
OBJECTIVES: To compare the different smile variables amongst patients with varying vertical skeletal patterns, and to find whether there is a correlation between the dynamic contributing factors and the vertical smile parameters. METHODS: This cross-sectional study was conducted at department of Orthodontics, Nishtar Institute of Dentistry, Multan, Pakistan from 01-10-2020 to 01-04-2021. The posed smiles of 120 participants, aging 15-25 years, having well-aligned dental arches were videotaped for objective measurements and comparisons with their underlying vertical skeletal growth patterns. RESULTS: The evaluation of smile parameters showed a significantly decreased inter-labial gap in patients with skeletal low angle in males (8.92±3.6mm) and females (9.44±2.58 mm) [p<0.004]. Upper lip length was significantly decreased in low angle (16.23±1.59 mm) cases for males as compared to vertically high (18.57±1.47 mm) and normal angle (18.24±2.08 mm) cases. Inter commissural width was increased significantly in the low angle cases (63.39±8.14 mm) when compared with the high angle cases (58.24±5.44 mm) in females. Maximal Incisal Display was significantly increased in high angle cases (9.03±1.31 mm) p<0.001 as compared to the low angle cases (7.64±1.98 mm). A 65.8% (n=79) of the sample showed a flat smile arc with 26.7% (n=32) having consonant smiles while 7.5% (n=9) showed a reverse smile arc. CONCLUSION: Smile dynamics are influenced by underlying skeletal patterns. Individuals with skeletally high angles showed an increased incisal display and an increased upper lip elevation upon smiling. While the low angle patterns displayed a decreased inter-labial gap and majority showed a flat smile arc.
目的:比较不同垂直骨骼类型患者的不同微笑变量,并探讨动态影响因素与垂直微笑参数之间是否存在相关性。方法:本横断面研究于2020年1月10日至2021年1月4日在巴基斯坦木尔坦Nishtar牙科研究所正畸科进行。120名年龄在15-25岁之间、牙弓排列整齐的参与者摆出的微笑被录了下来,用于客观测量,并与他们潜在的垂直骨骼生长模式进行比较。结果:微笑参数评估结果显示,骨角低患者的唇间间隙男性(8.92±3.6mm)和女性(9.44±2.58 mm)明显减小[p<0.004]。男性低角度上唇长度(16.23±1.59 mm)明显低于垂直角度上唇长度(18.57±1.47 mm)和正常角度上唇长度(18.24±2.08 mm)。低角度患者的关节间宽度(63.39±8.14 mm)明显高于高角度患者(58.24±5.44 mm)。高角度组最大切牙显示(9.03±1.31 mm)较低角度组(7.64±1.98 mm)显著增加(p<0.001)。65.8% (n=79)的人表现出平坦的微笑弧线,26.7% (n=32)的人表现出辅音微笑弧线,7.5% (n=9)的人表现出相反的微笑弧线。结论:微笑动态受到潜在骨骼模式的影响。骨骼角度高的个体在微笑时显示出更大的切面和更高的上唇。而低角度图案则显示唇间间隙减小,大多数人的微笑弧度是平坦的。
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引用次数: 0
CORRELATION BETWEEN MOLARS ANGULATION, OVERBITE AND VERTICAL SKELETAL PATTERN 磨牙成角、覆咬合与垂直骨型的关系
IF 0.3 Q4 MEDICINE, GENERAL & INTERNAL Pub Date : 2022-12-31 DOI: 10.35845/kmuj.2022.21297
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引用次数: 0
COMPARATIVE EVALUATION OF INTRAVITREAL DICLOFENAC PLUS BEVACIZUMAB VERSUS BEVACIZUMAB ALONE IN THE TREATMENT OF NAÏVE DIABETIC MACULAR EDEMA: A RANDOMIZED CONTROLLED TRIAL 玻璃体内双氯芬酸联合贝伐单抗与贝伐单抗单独治疗naÏve糖尿病性黄斑水肿的比较评价:一项随机对照试验
IF 0.3 Q4 MEDICINE, GENERAL & INTERNAL Pub Date : 2022-12-31 DOI: 10.35845/kmuj.2022.22708
Adnan Ahmad Mubashir
.
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引用次数: 0
SELF-REGULATION AS MEDIATOR IN PEER RELATIONSHIP, REJECTION SENSITIVITY WITH POSITIVE DEVELOPMENT AMONG ADOLESCENTS 自我调节作为同伴关系的中介青少年排斥敏感性与积极发展
IF 0.3 Q4 MEDICINE, GENERAL & INTERNAL Pub Date : 2022-12-31 DOI: 10.35845/kmuj.2022.20889
Sidra Batool, S. Shafiq
OBJECTIVE: To explore the mediating role of self-regulation in peer relationship, rejection sensitivity and positive development among adolescents. METHODS: This cross-sectional research was conducted at Department of Psychology from October, 2018 to September, 2019, comprised of two phases. In first phase, Self-Regulation Questionnaire (SRQ), Adolescent Peer Relations Instrument (APRI), Rejection Sensitivity Questionnaire (RSQ), and Positive Youth Development Inventory (PYDI), were translated into Urdu by forward-backward translation method. For pilot-testing, these scales were administered on 130 students and scales were found to be reliable. In second phase, Urdu versions of four instruments were st administered to a sample of 608 (males=330, females=278) college students of 1 nd and 2 years studying in various colleges of Sara-i-Alamgir by stratified proportionate random sampling technique.
目的:探讨自我调节在青少年同伴关系、拒绝敏感性和积极发展中的中介作用。方法:本横断面研究于2018年10月至2019年9月在心理学系进行,分为两个阶段。第一阶段采用正向倒译法将自我调节问卷(SRQ)、青少年同伴关系量表(APRI)、拒绝敏感性问卷(RSQ)和青少年积极发展量表(PYDI)翻译成乌尔都语。在初步测试中,对130名学生实施了这些量表,发现量表是可靠的。在第二阶段,采用分层比例随机抽样技术,对萨拉-阿拉姆吉尔不同学院的608名1年级和2年级的大学生(男330人,女278人)使用四种仪器的乌尔都语版本。
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引用次数: 0
POST-COVID COGNITIVE IMPAIRMENT AMONG GENERAL POPULATION OF KHYBER PAKHTUNKHWA: PAKISTAN 巴基斯坦开伯尔-普赫图赫瓦普通人群新冠肺炎后认知障碍
IF 0.3 Q4 MEDICINE, GENERAL & INTERNAL Pub Date : 2022-12-31 DOI: 10.35845/kmuj.2022.22179
S. Naveeda, Abid Saima, A. Zafar, Gul Sanam
OBJECTIVE: To assess and compare the cognitive functioning of post-Covid patient with non-Covid person among the general population of Khyber Pakhtunkhwa province of Pakistan. METHODS: This descriptive cross-sectional study was conducted from January to May 2021. Sample of 500 community members, including both post-Covid and non-Covid, from population of Khyber Pakhtunkhwa, Pakistan. Male and female with age of 18-64 years were included, age less than 18 years, having any nervous system or psychiatric illness or previous known cognitive impairment were excluded from the study. Validated Cognitive Functioning Self Reporting Scale (CFSS) questionnaire was used. Data was analyzed through SPSS V.25. RESULTS: Out of 600 approached, 500 (83.3%) participants responded to online questionnaire. Mean age of participants was 45+or-22 years, Majority (n=174: 34.7%) of participants were from 31- 40 years' age group. Hypertension (n=33;6.6%) and Diabetes Mellitus (n=30;6%) were the most common comorbid conditions;while 378 (75.6%) had no comorbidities. Mean CFSS values was 38.4+or-11.5 and 42.2+or-12.04 for male (n=230) and female (n=270) participants respectively. Based on standard cut off values of CFSS, mild, moderate and severe cognitive impairment was observed in 46 (24.8%), 127 (68.6%) and 12 (6.4%) cases of post-COVID and 19 (20.4%), 73 (78.4%) and 1 (1.0%) cases of non-COVID participants having no comorbidities. CONCLUSION: Cognitive performance was moderately affected among post COVID patients as compared to non-Covid population, compromising daily executive functioning as well as other elements of mental health such as attention, memory, spatial functioning & inhibition.
目的:评估和比较巴基斯坦开伯尔-普赫图赫瓦省普通人群中新冠肺炎后患者和非新冠肺炎患者的认知功能。方法:本描述性横断面研究于2021年1月至5月进行。来自巴基斯坦开伯尔-普赫图赫瓦人口的500名社区成员样本,包括新冠肺炎后和非新冠肺炎。年龄在18-64岁的男性和女性被纳入研究,年龄在18岁以下,有任何神经系统或精神疾病或以前已知的认知障碍被排除在研究之外。使用经验证的认知功能自我报告量表(CFSS)问卷。数据通过SPSS V.25进行分析。结果:在600名参与者中,500名(83.3%)参与者对在线问卷做出了回应。参与者的平均年龄为45+或22岁,大多数(n=174:34.7%)参与者来自31-40岁年龄组。高血压(n=33;6.6%)和糖尿病(n=30;6%)是最常见的合并症;378例(75.6%)无合并症。男性(n=230)和女性(n=270)参与者的平均CFSS值分别为38.4±11.5和42.2±12.04。根据CFSS的标准截断值,在46例(24.8%)、127例(68.6%)和12例(6.4%)新冠肺炎后病例以及19例(20.4%)、73例(78.4%)和1例(1.0%)无合并症的非新冠肺炎参与者中观察到轻度、中度和重度认知障碍。结论:与非新冠人群相比,新冠肺炎后患者的认知表现受到中度影响,影响了日常执行功能以及其他心理健康因素,如注意力、记忆、空间功能和抑制。
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引用次数: 0
期刊
Khyber Medical University Journal-KMUJ
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