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Three-dimensional evaluation of condylar position in skeletal Class I and Class II malocclusions along with vertical facial morphology 骨骼I类和II类错颌的髁突位置与垂直面部形态的三维评价
IF 0.4 Q4 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2022-11-29 DOI: 10.25259/apos_124_2022
Aditi Sharma, V. Pai, M. Hegde, Shreyas Rajaram
This study aimed to three-dimensionally evaluate and compare anatomic condylar position to glenoid fossa in skeletal Classes I and II malocclusions along with vertical facial morphology (VFM).Full skull 50 cone-beam computed tomographies (CBCTs) were taken with teeth in maximum intercuspation of patients aged 18–45 years who were grouped as skeletal Classes I and II, 25 each based on ANB angle and the patient’s right condyle was analyzed on CareStream-3D viewing software. The VFM was categorized based on the Jarabak ratio. Statistical analysis was performed using Mann–Whitney and Chi-square test.In skeletal Class II when compared to Class I, the condyle in the glenoid fossa was anteriorly positioned with reduced anterior (P = 0.006) and increased posterior (P = 0.04) distance showing eccentric position. The condyle was also positioned lower suggesting an increased distance in the upper joint space (P = 0.04). The reduced height of the articular eminence indicated the condylar path and its position. The angle of articular eminence (P = 0.44) was decreased. Statistically, significant difference was not found between the various vertical facial morphologies.CBCT provides precise diagnostic values of joint spaces in skeletal Classes I and II to differentiate ideal condylar position from non-ideal according to different skeletal patterns, VFM, and also to notice minor discrepancies in joint spaces quantitatively. Depending on increased or decreased distances in the joint spaces, one can identify any temporomandibular joint-related discrepancies.
本研究旨在三维评估和比较I类和II类骨骼错咬合患者的髁突与关节窝的解剖位置以及垂直面部形态(VFM)。对18-45岁的患者进行全颅骨锥束ct (cbct)扫描,其中50例患者的牙齿在最大间隙处,根据ANB角度分为骨骼I类和II类,每类25例,使用CareStream-3D查看软件对患者的右髁进行分析。VFM是根据贾拉巴克比率分类的。统计学分析采用Mann-Whitney检验和卡方检验。在骨骼II类中,与I类相比,肩关节窝的髁突位于前位,前位减少(P = 0.006),后位增加(P = 0.04),显示偏心位置。髁突位置也较低,表明上关节间隙距离增加(P = 0.04)。关节隆起高度的降低表明了髁突路径及其位置。关节隆起角度减小(P = 0.44)。在统计学上,不同的垂直面部形态之间没有显著差异。CBCT提供了骨骼I类和II类关节间隙的精确诊断价值,可以根据不同的骨骼模式、VFM区分理想的髁突位置和非理想的髁突位置,也可以定量地注意到关节间隙的微小差异。根据关节间隙距离的增加或减少,可以确定任何与颞下颌关节相关的差异。
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引用次数: 0
Comparison of retraction efficacy of titanium-molybdenum and titanium-niobium alloy wires – A prospective split-mouth study 钛钼金属丝与钛铌合金丝收放效果的比较-一项前瞻性裂口研究
IF 0.4 Q4 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2022-09-28 DOI: 10.25259/apos_133_2022
Nikhil Jain, Gauri S. Vichare, Veera I Bhosale
The study aimed to compare the efficacy of Titanium-Molybdenum (Ti-Mo) and Titanium-Niobium (Ti-Nb) alloy wires as retraction springs, by comparing: The amount and rate of canine retraction, the degree of canine rotation, the change in axial inclination of canines, and the associated anchorage loss.All 17 participants (age: 18–25 years) to be treated with the first premolar extraction approach by canine retraction were assigned Ti-Mo and Ti-Nb alloy T-loop springs to either of the upper quadrants randomly. Digital intraoral 3-D scans and panoramic radiographs orthopantomagram (OPG) were taken before (T0) and after (T1) the study period (4 months). 3-D superimposition was performed and using the digital models and OPG, changes in canine position, angulation, and anchorage loss were compared between the two groups.There was no significant difference between the two treatment groups for all the parameters pertaining to maxillary canine retraction, that is, canine retraction (P = 0.72), change in axial inclination of canines (P = 0.71), rotation of canines (P = 0.74), and anchorage loss (P = 0.13) as well as extraction space closure (P = 0.74).Ti-Nb and Ti-Mo alloy wires show a similar potency for use in retraction mechanics for orthodontic space closure.
本研究旨在比较钛钼(Ti-Mo)和钛铌(Ti-Nb)合金钢丝作为回缩弹簧的效果,通过比较:犬齿回缩的量和速度、犬齿旋转的程度、犬齿轴向倾角的变化以及相关的锚固损失。所有17名参与者(年龄:18-25岁)采用第一前磨牙拔牙方法,通过犬牙内收将Ti-Mo和Ti-Nb合金t型弹簧随机分配到上象限的任何一个象限。在研究期(4个月)前(T0)和研究期(T1)后(4个月)分别拍摄数字口内三维扫描和全景x线片(OPG)。利用数字模型和OPG进行三维叠加,比较两组犬位、成角和支抗损失的变化。两治疗组在上颌尖牙后缩(P = 0.72)、尖牙轴向倾斜度变化(P = 0.71)、尖牙旋转(P = 0.74)、支抗损失(P = 0.13)和拔牙间隙关闭(P = 0.74)等参数上均无显著差异。Ti-Nb和Ti-Mo合金丝在正畸间隙闭合的回缩力学中显示出相似的效力。
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引用次数: 0
Success rate of mini-implants based on side of insertion and type of jaw in adult patients undergoing orthodontic treatment – A systematic review and meta-analysis 基于插入侧位和颌骨类型的微型种植体在成人正畸治疗中的成功率-系统回顾和荟萃分析
IF 0.4 Q4 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2022-09-28 DOI: 10.25259/apos_156_2021
Rutuja Sheshnarayan Devadkar, Sheetal S. Potnis, N. Toshniwal, Shilpa Pharande, Vineet Vinay
To find out success rate of mini-implants based on side of insertion and type of jaw. The aim of orthodontic treatment is to maintain sufficient anchorage control to create appropriate force systems that provide the desired treatment effects. Implants have been used as skeletal anchorage devices for orthodontic purposes.The following study is a systematic review of mini-screws as an intervention to evaluate the stability and different related clinical parameters to define the success rate (outcome) depending on the side of insertion (i.e., right side and left side) and type of jaw (i.e., maxilla and mandible following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses).A total of 52 articles were extracted for qualitative synthesis among which 24 articles were reviewed for meta-analysis and the results showed that the maxilla is a better placement site for insertion of mini-implant (MI) than mandible with the odds ratio of 0.58, that is, the MI placement in the maxillary region is 58% more successful than mandibular region. The other parameter showed that the insertion of MI on the right side was more successful with the odds ratio of 0.50, that is, the insertion of MI on the right side of the jaw is 50% more successful than on the left side of the jaw.
目的:探讨基于植入侧位和下颌类型的微型种植体的成功率。正畸治疗的目的是保持足够的支抗控制,以创造适当的力系统,提供所需的治疗效果。种植体已被用作正畸目的的骨骼锚定装置。下面的研究是一项系统综述,将微型螺钉作为一种干预手段,评估其稳定性和不同的相关临床参数,以确定成功率(结果),这取决于插入的侧面(即右侧和左侧)和颌骨类型(即上颌和下颌骨,遵循系统综述和meta分析的首选报告项目)。共提取52篇文献进行定性综合,其中对24篇文献进行荟萃分析,结果显示上颌比下颌骨更适合植入微型种植体(MI),优势比为0.58,即上颌区植入微型种植体的成功率比下颌骨高58%。另一项参数显示右侧植入MI更成功,比值比为0.50,即右侧下颌植入MI比左侧下颌植入成功率高50%。
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引用次数: 0
Bibliometric analysis of research publications in three major orthodontic journals during 2012–2021 2012-2021年三大正畸期刊研究论文计量分析
IF 0.4 Q4 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2022-09-28 DOI: 10.25259/apos_137_2022
Jiachen Li, Kimberlee Onsiong, Elok Yi Lok Cheung, Yifan Lin
This study conducted a comprehensive bibliometric analysis of articles published from 2012 to 2021 in three orthodontic journals: The American Journal of Orthodontics and Dentofacial Orthopedics (AJODO), The Angle Orthodontist (AO), and European Journal of Orthodontics (EJO).Eligible articles published from 2012 to 2021 in AJODO, AO, and EJO were retrieved from the Web of Science Core Collection database and subsequently processed using CiteSpace software to generate their characteristics, including authorship, institution, geographic origin, keywords, and citation profiles.The three orthodontic journals published 4001 articles from 370 institutions in 95 countries from 2012 to 2021. The AJODO published the most articles (45.5%) followed by AO (31.3%) and EJO (23.2%). The most prolific country was the United States (US), followed by Brazil, South Korea, China, and Turkey. The authors from the US were heavily engaged in international collaborations, especially with South Korea and Brazil. The country and institutions with the highest citation counts per publication were Italy and the University of Bern (Switzerland), respectively. Pandis N was the most prolific author, and Proffit W was the most-cited author in the 4001 publications. The keywords that emerged most frequently were “children” followed by “orthodontic treatment” and “malocclusion.” Four of the 10 most-cited articles were related to digital dental technology.This bibliometric analysis provides a complete picture of the research published in three major orthodontic journals over the past decade. It comprehensively analyzes the authorship, country of origin, institutions, keywords, and citation profiles of the articles.
本研究对2012年至2021年发表在《American Journal of Orthodontics and Dentofacial Orthopedics》(AJODO)、《The Angle Orthodontist》(AO)和《European Journal of Orthodontics》(EJO)三家正畸期刊上的文章进行了全面的文献计量分析。从Web of Science Core Collection数据库中检索2012 - 2021年在AJODO、AO和EJO上发表的符合条件的文章,随后使用CiteSpace软件进行处理,生成其特征,包括作者、机构、地理来源、关键词和引文资料。2012年至2021年,这三家正畸期刊发表了来自95个国家370家机构的4001篇文章。AJODO发表的文章最多(45.5%),其次是AO(31.3%)和EJO(23.2%)。最多产的国家是美国,其次是巴西、韩国、中国和土耳其。来自美国的作者积极参与国际合作,特别是与韩国和巴西的合作。每份出版物引用数最高的国家和机构分别是意大利和伯尔尼大学(瑞士)。在4001个出版物中,Pandis N是最多产的作者,profit W是被引用最多的作者。出现频率最高的关键词是“儿童”,其次是“正畸治疗”和“错牙合”。被引用最多的10篇文章中有4篇与数字牙科技术有关。这个文献计量学分析提供了在过去十年中发表在三个主要正畸期刊上的研究的完整图景。它全面分析了文章的作者、原产国、机构、关键词和引用概况。
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引用次数: 1
Public perception of Invisalign® clear aligner treatment: A cross-sectional survey-based study 公众对Invisalign®透明矫正器治疗的看法:一项基于横断面调查的研究
IF 0.4 Q4 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2022-09-14 DOI: 10.25259/apos_127_2022
N. Almotairy
The demand for clear aligner treatment has increased in recent years. Thus, this study investigated public knowledge regarding Invisalign clear aligner treatment.A web-based survey was administered through different social media platforms covering different aspects of Invisalign treatment, namely: Treatment efficiency, patient discomfort, appliance esthetic attractiveness, oral hygiene maintenance, and treatment aesthetic results. Participants were also asked to outline their perception of Invisalign treatment cost. A Likert-type scale was used to rank the participant responses. Data were analyzed with the Chi-square test and Bonferroni correction for multiple comparisons.Out of 934 eligible adult participants, 19.6% were aware of Invisalign. Most of the Invisalign-familiar respondents were unaware of its cost (27.9%) but agree it is generally better (49.7%), requires fewer visits (38.2%), results in shorter treatment duration (39.4%) and reduced teeth discomfort (35%), more esthetically attractive (64%), yields easier oral hygiene maintenance (55.2%), and produces superior esthetic results (43.7%) than traditional braces. In addition, males and average-income participants were more likely to believe that Invisalign treatment produces superior esthetic results than traditional braces (P = 0.0002 and P = 0.002, respectively). Average-income participants also believed that Invisalign treatment was generally better (P < 0.0001). While participants in the age-range 55–64 years strongly believe, it is cheaper (P < 0.0001) than traditional braces.This study highlighted the lack of public knowledge about Invisalign treatment. The results also indicated the importance of ensuring public access to reliable information backed up by high-quality evidence.
近年来,对清洁矫正器治疗的需求有所增加。因此,本研究调查了公众对Invisalign透明矫正器治疗的认识。通过不同的社交媒体平台进行一项基于网络的调查,涵盖了Invisalign治疗的不同方面,即:治疗效率、患者不适、器械美观性、口腔卫生维护和治疗美学效果。参与者还被要求概述他们对隐形眼镜治疗费用的看法。李克特量表用于对参与者的回答进行排序。数据分析采用卡方检验和Bonferroni校正进行多重比较。在934名符合条件的成年参与者中,19.6%的人知道Invisalign。大多数熟悉隐形牙套的受访者不知道它的成本(27.9%),但认为它总体上更好(49.7%),就诊次数更少(38.2%),治疗时间更短(39.4%),牙齿不适减少(35%),更美观(64%),口腔卫生维护更容易(55.2%),美观效果优于传统牙套(43.7%)。此外,男性和平均收入的参与者更有可能相信Invisalign治疗比传统牙套产生更好的美学效果(P = 0.0002和P = 0.002分别)。平均收入的参与者也认为Invisalign治疗通常更好(P < 0.0001)。而年龄在55-64岁的参与者强烈认为,它比传统牙套更便宜(P < 0.0001)。这项研究强调了公众对隐形眼镜治疗知识的缺乏。调查结果还表明,确保公众获得有高质量证据支持的可靠信息的重要性。
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引用次数: 2
Interdisciplinary treatment in the digital era 数字时代的跨学科治疗
IF 0.4 Q4 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2022-08-03 DOI: 10.25259/apos_126_2022
K. W. Chang
In the digital era today, there are various new technologies could be applied to improve our collaboration and achieve a satisfied treatment outcome. While taking advantage of CAD/CAM technology, the traditional workflow can be simplified, altered, or reversed. Interdisciplinary treatment in the digital era is full of imagination and creativity!
在数码时代的今天,我们可以应用各种新技术来改善我们的合作,并取得令人满意的治疗结果。在利用CAD/CAM技术的同时,传统的工作流程可以被简化、改变或逆转。数字时代的跨学科治疗充满了想象力和创造力!
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引用次数: 0
Digital orthodontics and the future of our specialization 数字正畸和我们专业的未来
IF 0.4 Q4 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2022-07-25 DOI: 10.25259/apos_92_2022
F. Ciuffolo
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引用次数: 1
Comparison of the frictional resistance and optical properties of aluminum oxide and zinc oxide coated nickel titanium archwires – An in vitro study 氧化铝和氧化锌包覆镍钛弓丝的摩擦阻力和光学性能的比较-体外研究
IF 0.4 Q4 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2022-07-07 DOI: 10.25259/apos_24_2022
Jeyaram Palanivel, D. Srinivasan, N. C. S. Chakravathy
The friction that appears during sliding mechanics poses a clinical challenge to the orthodontist. The primary focus of an ideal tooth movement is to reduce the friction created at the archwire-bracket interface. Various variables (both biological and mechanical) affect the role of friction during orthodontic tooth movement. One among the variables which play a critical role is the archwire used in fixed mechanotherapy. Nickel-titanium (NiTi) archwires are widely used in clinical conditions due to their properties such as low force delivery and wider elastic working range. Innovations in the field of material science have led to the evolution of nickel titanium archwires with coating and surface modification to enhance the esthetics and decrease friction. Esthetics is of major concern in patients undergoing orthodontic treatment. As the esthetic demand keeps rising, the need for developing an esthetically acceptable material is required and it should not compromise on the clinical performance. The study aimed to evaluate and compare the frictional resistance and optical properties of ALUMINIUM oxide and zinc oxide-coated Ni-Ti archwires.The archwires were divided into three groups (n = 10), respectively: Group 1 – control group of uncoated NiTi archwires, GROUP 2 – zinc oxide coated NiTi archwires, and Group 3 – ALUMINIUM oxide coated NiTi archwires. The frictional resistance test was done using a universal testing machine, Instron, and optical properties were assessed using a colorimeter. The analysis of variance was used to determine whether a significant difference existed between the groups and a further post hoc Tukey test was used to determine the significant difference in the mean (P < 0.05).The two coated archwire groups – zinc oxide and ALUMINIUM oxide archwires showed a significant decrease in frictional resistance. Of the three groups, zinc oxide showed the least frictional resistance compared to the ALUMINIUM oxide-coated group and the uncoated group. Optical properties were calculated using the formula ΔE*ab for the three groups. Of which zinc oxide coated archwires were closest to VA1 indicating that it matches the shade of the natural tooth while the other two groups did not match the tooth color implying that it is not much esthetic as that of zinc oxide coated archwires.The zinc oxide-coated archwire resembles tooth color as well as has less frictional resistance compared to the other archwires.
在滑动力学过程中出现的摩擦对正畸医生提出了临床挑战。一个理想的牙齿运动的主要焦点是减少在弓线-托架界面产生的摩擦。在正畸牙齿移动过程中,各种变量(生物和机械)都会影响摩擦的作用。其中一个起关键作用的变量是在固定机械治疗中使用的弓丝。镍钛(NiTi)弓丝具有力传递小、弹性工作范围宽等特点,广泛应用于临床。在材料科学领域的创新导致镍钛拱丝的发展与涂层和表面改性,以提高美观性和减少摩擦。在接受正畸治疗的患者中,美学是主要关注的问题。随着审美需求的不断提高,需要开发一种美学上可接受的材料,而不应损害临床性能。本研究旨在评价和比较氧化铝和氧化锌包覆镍钛拱线的摩擦阻力和光学性能。将弓丝分为3组(n = 10),分别为:第1组-未涂覆NiTi弓丝对照组,第2组-氧化锌涂覆NiTi弓丝,第3组-氧化铝涂覆NiTi弓丝。摩擦阻力测试使用万能试验机Instron进行,光学性能使用色度计进行评估。采用方差分析确定两组间是否存在显著性差异,并进一步采用事后Tukey检验确定平均值的显著性差异(P < 0.05)。两种包覆的氧化锌和氧化铝弓丝的摩擦阻力显著降低。在这三组中,氧化锌与氧化铝涂层组和未涂层组相比显示出最小的摩擦阻力。使用公式ΔE*ab计算三种基团的光学性质。其中氧化锌包覆的弓线最接近VA1,表明它与天然牙齿的颜色相匹配,而另外两组与牙齿的颜色不匹配,这意味着它没有氧化锌包覆的弓线那么美观。氧化锌包覆的弓丝类似于牙齿的颜色,并且与其他弓丝相比具有更小的摩擦阻力。
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引用次数: 1
The antimicrobial effect of doxycycline and doped ZnO in TiO2 nanotubes synthesized on the surface of orthodontic mini-implants 正畸微型种植体表面合成的TiO2纳米管中强力霉素和掺杂ZnO的抗菌效果
IF 0.4 Q4 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2022-06-23 DOI: 10.25259/apos_14_2022
Saeed Noorollahian, Marzie Kachuie, Zahra Hatamzade, Majid Moghadam, T. Narimani
Anchorage preservation is crucial in orthodontic treatment success. Mini-implants make a revolution in this domain. The failure of orthodontic mini-implants due to inflammation and infection is one of the reasons for anchorage loss. The purpose of this study was to evaluate the effect of a novel mini-implant surface modification to improve resistance against microbial contamination and surrounding tissue inflammation.Twenty-four orthodontic mini-implants (Jeil Medical Corporation, Korea) with 1.6 mm diameter and 8 mm length were randomly divided into three groups: Group 1: Control group, Group 2: Nanotubes were made on the surface with anodisation, and Group 3: Zinc Oxide (ZnO) doped into nanotubes, and then doxycycline is added to them. The anti-bacterial efficacy against Porphyromonas gingivalis was evaluated using the disk diffusion method. To analyze data, Kruskal–Wallis, Friedman, and Wilcoxon tests were done. The significance level was set at 0.05.No zone of the inhibition was formed in Groups 1 and 2. In Group 3, the mean (SD) diameter of the inhibition zone in the first 5-day to sixth 5-day were 38.7(8.2), 25(4.8), 17.8(5.6), 7.63(5.37), 1.5(2.83), and 0 millimeters, respectively.Nanotubes containing doped ZnO and Doxycycline are capable of preventing bacterial growth around the mini implant surfaces for at least up to 30 days. To manage inflammation of surrounding tissues of mini-implants, nanotubes are not effective alone. Therefore, the presence of diffusible materials in addition to nanotubes on the surface of mini-implants is necessary.
固支体的保存是正畸治疗成功的关键。微型植入物在这个领域掀起了一场革命。正畸微型种植体因炎症和感染而失败是导致支抗丢失的原因之一。本研究的目的是评估一种新型微型种植体表面修饰的效果,以提高对微生物污染和周围组织炎症的抵抗力。将直径1.6 mm、长度8 mm的24颗正畸微型种植体(Jeil Medical Corporation, Korea)随机分为3组:第1组:对照组;第2组:表面阳极氧化制备纳米管;第3组:纳米管中掺杂氧化锌(ZnO),然后加入强力霉素。采用纸片扩散法评价其对牙龈卟啉单胞菌的抗菌效果。为了分析数据,进行了Kruskal-Wallis、Friedman和Wilcoxon测试。显著性水平设为0.05。1、2组未形成抑制区。第3组前5天至第6天的平均抑制区直径(SD)分别为38.7(8.2)、25(4.8)、17.8(5.6)、7.63(5.37)、1.5(2.83)和0 mm。含有掺杂氧化锌和强力霉素的纳米管能够阻止细菌在微型植入物表面生长至少30天。为了控制微型植入物周围组织的炎症,纳米管不是单独有效的。因此,除了纳米管外,微型植入物表面的扩散材料是必要的。
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引用次数: 1
Platelet-rich derivatives for accelerating the rate of orthodontic tooth movement - a systematic review and meta-analysis 血小板丰富的衍生物加速正畸牙齿移动的速度-系统回顾和荟萃分析
IF 0.4 Q4 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2022-06-21 DOI: 10.25259/apos_6_2022
Deepika Katyal, A. George, R. Jain, A. Balasubramaniam, M. Srirengalakshmi, Nikhilesh R Vaid
The aim of this systematic review and meta-analysis was to report on the effects of using platelet-rich derivatives on the rate of tooth movement.Both electronic and manual searches were performed with specific eligibility criteria based on population, intervention, comparison, outcome, and study design. Risk of bias (RoB) assessment was done using the Cochrane RoB tool 2, the data were pooled and analyzed using review manager 4.5, and certainty of the evidence was assessed using the Grading of Recommendations Assessment, Development, and Evaluation approach. Two independent reviewers performed the study selection, data extraction, and analysis. Nine studies were included for qualitative analysis and two of them were subjected to meta-analysis.The standard mean difference for the rate of canine distal movement with platelet-rich derivatives was not significantly higher than controls at any of the time intervals (P > 0.0001). Rotation of canines, molar mesialization, and pain scores were not affected by the administration of platelet-rich derivatives for accelerating tooth movement. A moderate to high RoB was noted in the included studies and the certainty of the available evidence as assessed by the GRADE approach was moderate.The included studies presented with high heterogeneity and more high-quality studies with strict protocols are needed. Even though individual studies report significant acceleration of tooth movement following administration of PR derivatives, moderate certainty of evidence suggests no acceleratory effect on tooth movement.
本系统综述和荟萃分析的目的是报告使用富血小板衍生物对牙齿移动速度的影响。电子和人工检索均采用基于人群、干预、比较、结果和研究设计的特定资格标准进行。使用Cochrane RoB工具2进行偏倚风险(RoB)评估,使用review manager 4.5对数据进行汇总和分析,并使用分级推荐评估、发展和评估方法评估证据的确定性。两名独立的审稿人进行了研究选择、数据提取和分析。纳入9项研究进行定性分析,其中2项进行meta分析。在任何时间间隔内,具有血小板丰富衍生物的犬远端运动率的标准均差均不显著高于对照组(P > 0.0001)。犬齿旋转、磨牙靠近和疼痛评分不受富血小板衍生物加速牙齿运动的影响。在纳入的研究中注意到中度至高的RoB,并且通过GRADE方法评估的现有证据的确定性为中等。纳入的研究具有较高的异质性,需要更多具有严格方案的高质量研究。尽管个别研究报告了服用PR衍生物后牙齿运动明显加速,但中等确定性的证据表明对牙齿运动没有加速作用。
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引用次数: 1
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APOS Trends in Orthodontics
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